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APOE Genotype Disclosure Influences Decisions About Future Planning but not Adoption of Healthy Lifestyle Changes in Cognitively Unimpaired Individuals J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2024-03-09 Dominique L. Popescu, Athene K. Lee, Edmund Arthur, Louisa I. Thompson, Jessica Alber
BackgroundStudies have shown apolipoprotein E (APOE) genotype disclosure to be safe and well-tolerated in cognitively unimpaired (CU) older adults. This study aimed to examine the effect of the disclosure process on decisions about future directives and health behaviors in community-dwelling CU older adults from the Butler Alzheimer’s Prevention Registry (BAPR).MethodsCU APOE E4 non-carriers (n = 106)
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Physical Exercise for Treating the Anxiety and Depression Symptoms of Parkinson’s Disease: Systematic Review and Meta-Analysis J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2024-03-06 Valton Costa, José Mario Prati, Alice de Oliveira Barreto Suassuna, Thanielle Souza Silva Brito, Thalita Frigo da Rocha, Anna Carolyna Gianlorenço
BackgroundDepression and anxiety are non-motor symptoms of Parkinson’s disease (PD). Physical exercise is a promising approach to reducing neuropsychological burden. We aimed to comprehensively synthesize evidence regarding the use of exercise for treating depression and anxiety symptoms in PD.MethodsSystematic review and meta-analysis following PRISMA recommendations. Searches on PubMed, Cochrane
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Forecasted Dementia Prevalence in Portugal (2020-2080) J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2024-03-04 Sara Alves, Natália Duarte, Barbara Gomes
Dementia is a global public health challenge, and its impact on Portugal is yet unclear. This study forecasts dementia prevalence in Portugal until 2080. Using the Gonçalves-Pereira et al (2021) method, we estimated dementia cases among older adults (≥65 years) in the community. Applying age-sex specific prevalence rates of the Gonçalves-Pereira study to population projections for Portugal between
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A Systematic Review of Dementia Research Priorities J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2024-02-10 Manonita Ghosh, Pelden Chejor, Melanie Baker, Davina Porock
IntroductionPatient involvement is a critical component of dementia research priority-setting exercises to ensure that research benefits are relevant and acceptable to those who need the most. This systematic review synthesises research priorities and preferences identified by people living with dementia and their caregivers.MethodsGuided by Joanna Briggs Institute methodology, and Preferred Reporting
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Multiple Early Biomarkers to Predict Cognitive Decline in Dementia-Free Older Adults J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2024-02-09 Juan Li, Zhiying Jiang, Shengjie Duan, Xingxing Zhu
IntroductionBaseline olfactory impairment, poor performance on cognitive test, and medial temporal lobe atrophy are considered biomarkers for predicting future cognitive decline in dementia-free older adults. However, the combined effect of these predictors has not been fully investigated.MethodsA group of 110 participants without dementia were continuously recruited into this study, and underwent
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The Starkstein Apathy Scale-Italian Version: An Update J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2024-01-18 Ciro R. Ilardi, Maria Sannino, Giovanni Federico, Mara A. Cirillo, Carlo Cavaliere, Alessandro Iavarone, Elisabetta Garofalo
Apathy can manifest in various neuropsychiatric conditions, as well as in individuals who experience significant stressful life events or suffer from underlying internal medical conditions. The Starkstein Apathy Scale (SAS) is recognized as a reliable screening tool, besides being endorsed by the International Parkinson and Movement Disorder Society to assess apathy in patients with Parkinson’s disease
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The Care Needs of Patients With Cognitive Impairment in Late-Stage Parkinson’s Disease J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2024-01-17 Jennifer S. Pigott, Bastiaan R. Bloem, Stefan Lorenzl, Wassilios G. Meissner, Per Odin, Joaquim J. Ferreira, Richard Dodel, Anette Schrag
BackgroundCognitive impairment is common in Parkinson’s disease (PD), but care needs and resource use for those with significant cognitive impairment are not well established.Methods675 participants with PD from the international Care of Late-Stage Parkinsonism (CLaSP) study were grouped into those without (n = 333, 49%) and with cognitive impairment (MMSE < 24/30 or diagnosis of dementia or Mild Cognitive
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Quantitative EEG in the Differential Diagnosis of Dementia Subtypes J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2024-01-13 Yeşim Olğun, Cana Aksoy Poyraz, Melda Bozluolçay, Burç Çağrı Poyraz
ObjectiveMost neurodegenerative dementias present with substantial overlap in clinical features. Therefore, differential diagnosis is often a challenging task necessitating costly and sometimes invasive diagnostic procedures. A promising, non-invasive and cost-effective method is the widely available electroencephalography (EEG).MethodsTwenty-three subjects with Alzheimer’s disease (AD), 28 subjects
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Association of Higher Mediterranean Diet Adherence With Lower Prevalence of Disability and Symptom Severity, Depression, Anxiety, Stress, Sleep Quality, Cognitive Impairment, and Physical Inactivity in Older Adults With Multiple Sclerosis. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-11-29 Christina Tryfonos,Eleni Pavlidou,Theofanis Vorvolakos,Olga Alexatou,Konstantinos Vadikolias,Maria Mentzelou,Gerasimos Tsourouflis,Aspasia Serdari,Georgios Antasouras,Sousana K Papadopoulou,Exakousti-Petroula Aggelakou,Constantinos Giaginis
A good nutritional status and healthy diets may decelerate disease disability and symptom severity and quality of life of peoples with multiple sclerosis (MS). Mediterranean diet (MD) can prevent several chronic diseases, including neurodegenerative disease. This is an observational, cross-sectional study on 279 older adults with MS, aiming to investigate the effects of MD against several aspects of
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Association Between Mid-arm Muscle Circumference and Cognitive Function: A Longitudinal Study of Chinese Adults. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-11-22 Hillary B Spangler,David H Lynch,Annie Green Howard,Hsiao-Chuan Tien,Shufa Du,Bing Zhang,Huijun Wang,Penny Gordon Larsen,John A Batsis
BACKGROUND Dementia affects 55 million people worldwide and low muscle mass may be associated with cognitive decline. Mid-arm muscle circumference (MAMC) correlates with dual-energy Xray absorptiometry and bioelectrical impedance analyses, yet are not routinely available. Therefore, we examined the association between MAMC and cognitive performance in older adults. METHODS We included community-dwelling
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Impact of Care-Recipient Relationship Type on Quality of Life in Community-Dwelling Older Adults With Dementia Over Time. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-11-11 Aiping Lai,Lauren E Griffith,Ayse Kuspinar,Jenna-Smith Turchyn,Julie Richardson
INTRODUCTION Maintaining quality of life (QoL) has been identified as the primary goal of care services for person living with dementia (PLWD). METHODS A secondary analysis was conducted on five rounds of the National Health and Aging Trends Study (NHATS) over 4 years. A generalized estimating equation (GEE) was used to examine the prediction of relationship type on older adults' QoL through four domains:
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Depressive Symptoms are Associated With C-Reactive Protein in Older Adults With Obesity. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-11-11 Henry D Heisey,Clifford Qualls,Dennis T Villareal,Martha Belen Segoviano-Escobar,Maria Liza Duremdes Nava,Jennifer R Gatchel,Mark E Kunik
OBJECTIVES To test the hypothesis that depressive symptoms vary with high-sensitivity C-reactive protein (hs-CRP), among older adults with obesity. METHODS This was a cross-sectional, secondary analysis of baseline data from two related lifestyle intervention trials. The study sample comprises 148 consecutively recruited, community-dwelling older adults (age >=65 years) without severe psychiatric illness
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A First Exploration: Can Eye Movement Desensitization and Reprocessing Improve Cognition in Older Adults With Posttraumatic Stress Disorder? J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-10-23 Ellen M J Gielkens,Gina Rossi,Sebastiaan P J van Alphen,Sjacko Sobczak
OBJECTIVES In older adults, PTSD is associated with decreased verbal learning and executive dysfunction. Therefore, feasibility of EMDR-treatment to improve cognitive performance in older adults with PTSD was examined. Additionally, we investigated pre-treatment correlation with often co-occurring risk factors for cognitive decline (sleep problems, depressive disorder, physical inactivity, childhood
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The Relationship Between Apathy and Cognitive Impairment Among Hispanic/Latin Americans: A Preferred Reporting Items for Systematic Reviews and Meta-Analyses Systematic Review. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-10-19 Joshua M Garcia,Jai Sehgal,Jennifer L Thompson,Steven Paul Woods,Luis D Medina
OBJECTIVES The primary aim was to evaluate apathy assessment measures in relation to cognitive impairment among Hispanic/Latin Americans. METHODS A systematic review on the relationship between apathy and cognitive impairment among Hispanic/Latin Americans across normal aging and neurocognitive disorders was conducted according to preferred reporting items for systematic reviews and meta-analyses (PRISMA)
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A Novel Approach to Monitoring Cognitive Adverse Events for Interventional Studies Involving Advanced Dementia Patients: Insights From the Electroconvulsive Therapy for Agitation in Dementia Study. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-10-17 Soohyun Park,Brent P Forester,Maria I Lapid,David G Harper,Adriana P Hermida,Sharon K Inouye,Shawn M McClintock,Louis Nykamp,Georgios Petrides,Eva M Schmitt,Stephen J Seiner,Martina Mueller,Regan E Patrick
OBJECTIVE To develop an individualized method for detecting cognitive adverse events (CAEs) in the context of an ongoing trial of electroconvulsive therapy for refractory agitation and aggression for advanced dementia (ECT-AD study). METHODS Literature search aimed at identifying (a) cognitive measures appropriate for patients with advanced dementia, (b) functional scales to use as a proxy for cognitive
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The Relationship Between Autonomic Dysfunction and Mood Symptoms in De Novo Parkinson's Disease Patients Over Time. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-10-13 Adrianna M Ratajska,Connor B Etheridge,Francesca V Lopez,Lauren E Kenney,Katie Rodriguez,Rachel N Schade,Joshua Gertler,Dawn Bowers
BACKGROUND Autonomic dysfunction is prevalent in Parkinson's disease (PD) and can worsen quality of life. We examined: (a) whether specific autonomic symptoms were more strongly associated with anxiety or depression in PD and (b) whether overall autonomic dysfunction predicted mood trajectories over a 5-year period. METHODS Newly diagnosed individuals with PD (N = 414) from the Parkinson's Progression
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Depressive Symptoms Moderate the Association Between Functional Level at Admission to Intensive Post-Stroke Rehabilitation and Effectiveness of the Intervention. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-10-12 Salvatore Mazzeo,Silvia Pancani,Alessandro Sodero,Chiara Castagnoli,Angela Maria Politi,Monica Barnabè,Francesca Ciullini,Marco Baccini,Antonello Grippo,Bahia Hakiki,Claudio Macchi,Francesca Cecchi
INTRODUCTION Previous studies showed that depression acts as an independent factor in functional recovery after stroke. In a prospective cohort of patients admitted to intensive inpatient rehabilitation after a stroke, we aimed to test depression as a moderator of the relationship between the functional level at admission and the effectiveness of rehabilitation at discharge. METHODS All patients admitted
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Antidementia Medication Use in Nursing Home Residents. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-09-16 Brian R Ott,Carl Hollins,Jennifer Tjia,Jonggyu Baek,Qiaoxi Chen,Kate L Lapane,Matthew Alcusky
BACKGROUND Antidementia medication can provide symptomatic improvements in patients with Alzheimer's disease, but there is a lack of consensus guidance on when to start and stop treatment in the nursing home setting. METHODS We describe utilization patterns of cholinesterase inhibitors (ChEI) and memantine for 3,50,197 newly admitted NH residents with dementia between 2011 and 2018. RESULTS Overall
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Effects of Sport Stacking on Cognition in Patients With Mild Alzheimer's Disease and MCI: Preliminary Findings of Randomized Controlled Trial. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-09-05 Ziying Yang,Jun Yang,Doris S F Yu,Dunxiu Liu,Fu Ding
OBJECTIVE This mixed-method pilot study aims to investigate the feasibility and preliminary effects of sport stacking on cognitive function in individuals with mild Alzheimer's disease (AD) and those with mild cognitive impairment (MCI). METHODS Twenty-four community-dwelling subjects with confirmed mild AD or MCI were evenly randomly assigned to either the 12-week sport stacking intervention group
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Does the Etiology, Phenomenology and Motor Subtype of Delirium Differ When It Occurs in Patients With An Underlying Dementia?: A Multi-Site, International Study. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-08-11 Kevin Glynn,Frank McKenna,Kevin Lally,Sandeep Grover,Subho Chakrabarti,Surendra K Mattoo,Ajita Avasthi,Akhilesh Sharma,Dimitrios Adamis,Fahad Awan,Colum P Dunne,John McFarland,Faiza Jabbar,Henry O'Connell,Maeve Leonard,David J Meagher
OBJECTIVES To compare the etiology, phenomenology and motor subtype of delirium in patients with and without an underlying dementia. METHODS A combined dataset (n = 992) was collated from two databases of older adults (>65 years) from liaison psychiatry and palliative care populations in Ireland and India. Phenomenology and severity of delirium were analysed using the Delirium Symptom Rating Scale
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Burden and Depression among Empirically-Derived Subgroups of Family Caregivers for Individuals With Dementia. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-08-08 Nina Ahmad,Zachary J Kunicki,Ellen Tambor,Gary Epstein-Lubow,Geoffrey Tremont
Dementia caregiving experiences are not universal and different factors may influence the risk for burden and depression. This study examined factors such as the relationship with the care recipient, severity of dementia, and relationship satisfaction to uncover different types of caregiver burden profiles using baseline assessment for a telephone-based intervention study for dementia caregivers. Participants
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Caregiver Burden in Parkinson Disease: A Scoping Review of the Literature from 2017-2022. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-08-08 Whitley W Aamodt,Benzi M Kluger,Miray Mirham,Anna Job,Samantha E Lettenberger,Philip E Mosley,Sandhya Seshadri
Caregiver burden is a term that refers to the adverse effect of caregiving on the physical, emotional, social, spiritual, and financial well-being of the caregiver. Caregiver burden is associated with providing care to an individual with a chronic illness or disability, and the unique symptoms of Parkinson disease (PD) can amplify a patient's needs and reliance on others, leading to adverse outcomes
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Language Impairment in Vascular Dementia: A Clinical Review. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-08-08 Joël Macoir
Vascular cognitive impairment (VCI) encompasses a wide range of conditions, including cognitive impairment associated with stroke or vascular brain injury, mild vascular cognitive impairment, and vascular dementia (VD). Knowledge of language impairment associated with VD is far less extensive than that of Alzheimer's disease. Although not prevalent in VD, impairment in language skills has been reported
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Atypical Neuropsychiatric Presentation of FTD-ALS Caused by a Pathogenic Repeat Expansion in C9orf72: A Case Report. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-08-07 Marissa A LeBlanc,Amy Gough,Andrea L Rideout,Sarah Dyack,Kathleen Singh,Meagan MacNeil
The case report describes the presentation of a 42-year-old male ultimately diagnosed with FTD-ALS caused by a genetic mutation, who initially presented with atypical psychiatric symptoms. Given that the initial clinical manifestations of FTD-ALS can be quite variable, the diagnosis is often challenging; the case report aims to highlight several key considerations in the diagnostic assessment, including
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Behavioral Impairments and Increased Risk of Cortical Atrophy Risk Scores Among World Trade Center Responders. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-08-05 Allen P F Chen,Zahinoor Ismail,Frank D Mann,Evelyn J Bromet,Sean A P Clouston,Benjamin J Luft
Objective: World Trade Center (WTC) responders are susceptible to both cognitive and neuropsychiatric impairments, particularly chronic posttraumatic stress disorder. The present study examined self-reported behavioral impairments in a sample of 732 WTC responders, 199 of whom were determined to have high risk of WTC-related cortical atrophy by an artificial neural network. Results: We found that responders
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Minor Phenomena in Parkinson's Disease-Prevalence, Associations, and Risk of Developing Psychosis. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-08-05 Ruth B Schneider,Peggy Auinger,Roseanne D Dobkin,Kelly A Mills,Catherine V Kulick-Soper,Taylor L Myers,Monica Korell,Gregory M Pontone,Melissa J Nirenberg
BACKGROUND Minor phenomena, including passage phenomena, feeling of presence, and illusions, are common and may represent a prodromal form of psychosis in Parkinson's disease (PD). We examined the prevalence and clinical correlates of minor phenomena, and their potential role as a risk factor for PD psychosis. METHODS A novel questionnaire, the Psychosis and Mild Perceptual Disturbances Questionnaire
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Predicting Caregiver Communications in a Geriatric Clinic. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-08-04 John T Martin,Jason R Anderson,Kimberly R Chapman,Natalie Kayani,Jennifer Drost,Mary Beth Spitznagel
The current study evaluated the use of a machine learning model to determine benefit of medical record variables in predicting geriatric clinic communication requirements. Patient behavioral symptoms and global cognition, medical information, and caregiver intake assessments were extracted from 557 patient records. Two independent raters reviewed the subsequent 12 months for documented (1) incoming
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Emotion Regulation in Dementia Caregiving: The Role of Neuropsychiatric Symptoms and Attachment Orientation. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-08-04 Tânia Brandão,Rute Brites,João Hipólito,Odete Nunes,Catarina Tomé Pires
Family caregivers are usually the main source of support for persons living with dementia, being exposed to a loved one's suffering, which can lead to experiencing strong and negative emotions. This study aimed to identify factors capable of explaining individual differences in the way caregivers regulate their emotions. This cross-sectional study included 78 informal caregivers (M = 64.84 years; SD
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Late-Life High Blood Pressure and Enlarged Perivascular Spaces in the Putaminal Regions of Community-Dwelling Japanese Older Persons. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-08-03 Ayumi Tachibana,Jun-Ichi Iga,Yasuko Tatewaki,Benjamin Thyreau,Hongkun Chen,Tomoki Ozaki,Taku Yoshida,Yuta Yoshino,Hideaki Shimizu,Takaaki Mori,Yoshihiko Furuta,Mao Shibata,Tomoyuki Ohara,Jun Hata,Yasuyuki Taki,Shigeyuki Nakaji,Tetsuya Maeda,Kenjiro Ono,Masaru Mimura,Kenji Nakashima,Minoru Takebayashi,Toshiharu Ninomiya,Shu-Ichi Ueno,
BACKGROUND Enlarged perivascular spaces (EPVS) of the brain may be involved in dementia, such as Alzheimer's disease and cerebral small vessel disease (CSVD). Hypertension has been reported to be a risk factor for dementia and CSVD, but the association between blood pressure (BP) and perivascular spaces is still unclear. The aim of this study was to determine the association between BP and EPVS volumes
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Virtual Group Music Therapy for Apathy in Parkinson's Disease: A Pilot Study. J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-05-18 Deepal Shah-Zamora,Sharlet Anderson,Brandon Barton,Jori E Fleisher
OBJECTIVE To evaluate the effect of virtual group music therapy on apathy in people with Parkinson's disease (PD). INTRODUCTION Apathy affects 40% of people with PD, lacks effective therapies, and independently predicts poorer quality of life and greater caregiver burden. Music therapy is the clinical application of music to address a person's physical or emotional needs and is effective in treating
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Assessment of Personality Disorders in Older Adults. A Practice Guide J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-05-12 Sebastiaan PJ van Alphen, Sanne van der Werff, Erlene Rosowsky, Daniel L Segal, Gina Rossi
Assessment of personality disorders (PDs) in older adults is a nuanced trade of its own. The aim of this practice guide is to illustrate gerontological assessment challenges using 3 case vignettes....
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Geriatric Psychiatrists’ Perspectives on Palliative Care: Results From A National Survey J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-05-09 Hana Elhassan, Gregg A. Robbins-Welty, Jerad Moxley, M. Carrington Reid, Daniel Shalev
ObjectivesOlder adults with psychiatric illnesses often have medical comorbidities that require symptom management and impact prognosis. Geriatric psychiatrists are uniquely positioned to meet the ...
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Facial Expression Recognition of Emotional Situations in Mild and Moderate Alzheimer’s Disease J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-05-09 Michelle Brandt, Felipe de Oliveira Silva, José Pedro Simões Neto, Maria Alice Tourinho Baptista, Tatiana Belfort, Isabel Barbeito Lacerda, Marcia Cristina Nascimento Dourado
Background: Recognizing emotional situations may be impaired in people with Alzheimer’s disease (AD). Purpose: We examined differences in the comprehension of an emotional situation in healthy olde...
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Baseline Differences in Driving Frequency as a Predictor of Cognitive Decline and Alzheimer’s Disease J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-05-06 Luke R. Miller, Christopher Reed, Ross Divers, Matthew Calamia
ObjectiveTo extend prior research by examining daily driving frequency as a predictor of cognitive decline and later diagnosis of Alzheimer’s disease.Methods1,426 older adults completed batteries o...
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Support Needs in Carers of People With Parkinson’s From Early to Later Stages: A Qualitative Study With 36 Carers in 11 European Countries J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-04-20 Rowena K. Merritt, Sarah Hotham, Anette Schrag
BackgroundParkinson’s Disease (PD) is associated with considerable carer burden, but there has been little qualitative research on the support needs of carers of People with Parkinson’s (PwP).Metho...
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Advances in the Diagnosis and Management of Psychotic Symptoms in Neurodegenerative Diseases: A Narrative Review J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-03-20 Andreea L. Seritan
Background: Approximately 15% of older adults may experience psychotic phenomena. Primary psychiatric disorders that manifest with psychosis (delusions, hallucinations, and disorganized thought or ...
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A Prescription for Wellness in Early PD: Just What the Doctor Ordered J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-03-13 Bradley McDaniels, Gregory M. Pontone, Adrienne M. Keener, Indu Subramanian
BackgroundBeing diagnosed with a neurodegenerative disease is a life-changing event and a critical time to help patients cope and move forward in a proactive way. Historically, the main focus of Pa...
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Pharmacological and Behavioral Interventions for Fatigue in Parkinson's Disease: A Meta-Analysis of Randomized Controlled Trials J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-03-14 Chenke Jiang, Yijun Luo, Yiqian Qu, Che Wang, Zhan Li, Jia Zhou, Zhenghao Xu
ObjectiveThis study aims to evaluate pharmacological and behavioral interventions for the treatment of fatigue in Parkinson's disease (PD) patients.MethodsWe systematically searched PubMed, PsycINF...
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Subjective Complaints are Similar in Subjective Cognitive Decline and Early-Stage Alzheimer’s Disease when Assessed in a Memory Clinic Setting J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-03-09 Anna E. Bruus, Gunhild Waldemar, Asmus Vogel
BackgroundSubjective cognitive complaints are generally poorly associated with objective memory functioning in older persons. Subjective cognitive decline (SCD) is a key feature in SCD and amnestic...
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Vitamin D Insufficiency is Associated with Higher Incidence of Dementia, a Large Community-Based Retrospective Cohort Study J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-03-08 David Kiderman, Niv Ben-Shabat, Avishai M. Tsur, Saar Anis, Abdulla Watad, Arnon D. Cohen, Ziv Paz, Howard Amital
IntroductionActive metabolite of vitamin D has neuro-immunomodulatory and neuroprotective properties. However, there is still a debate about the potential association between low serum levels of hy...
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Anxiety in Parkinson’s Patients: What’s Timing Got to Do with It? J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-03-09 Elisabeth C. DeMarco, Zidong Zhang, Hunter Robinson, Leslie Hinyard
Background: Parkinson’s Disease (PD) affects over 10 million people worldwide. Many PD patients experience comorbid anxiety disorders, which have been correlated with reduced quality of life and ca...
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Towards a better Comprehension and Management of Pain and Psychological Distress in Parkinson’s: The Role of Catastrophizing J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-02-05 Sylvia Zimmers, Léonore Robieux, Catherine Bungener
ObjectivesPain is very prevalent in Parkinson’s and challenging to manage. As many people with Parkinson’s (PwP) with pain suffer from anxious and depressive symptoms, we examined the role of catas...
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Comparative Efficacy, Safety, and Acceptability of Pimavanserin and Other Atypical Antipsychotics for Parkinson’s Disease Psychosis: Systematic Review and Network Meta-Analysis J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-01-31 Ismaeel Yunusa, Nazia Rashid, Roxanna Seyedin, Deepika Paratane, Krithika Rajagopalan
BackgroundThe current comparative efficacy, safety, and acceptability of atypical antipsychotics (AAPs) in treating Parkinson's Disease Psychosis (PDP) are not entirely understood.ObjectiveTo evalu...
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Regional Vulnerability of the Corpus Callosum in the Context of Cardiovascular Risk J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-01-29 Anna M. VandeBunte, Corrina Fonseca, Emily W. Paolillo, Eva Gontrum, Shannon Y. Lee, Joel H. Kramer, Kaitlin B. Casaletto
Many factors outside of cardiovascular health can impact the structure of white matter. Identification of reliable and clinically meaningful biomarkers of the neural effects of systemic and cardiov...
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Visuoconstructional Abilities of Patients With Subjective Cognitive Decline, Mild Cognitive Impairment and Alzheimer’s Disease J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-01-11 Paula Knechtl, Johann Lehrner
BackgroundVia the Vienna Visuoconstructional Test 3.0 (VVT 3.0) delayed recall we combined the assessment of visuoconstructive abilities and memory and investigated the test’s potential to support ...
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Understanding Barriers and Facilitators to Online and App Activities for People Living With Dementia and Their Supporters J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-01-04 Abigail R. Lee, Orii McDermott, Martin Orrell
BackgroundStigma often surrounds people with dementia when it comes to use of computer technology, although evidence does not always support this. More understanding is needed to investigate attitu...
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Assessment of a Suicide Prevention Gatekeeper Training Program for Nursing Home Staff J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-01-03 Alice Demesmaeker, Nicolas Baelde, Ali Amad, Jean Roche, Marie Playe, Guillaume Vaiva, Alina Amariei, Wanda Blervaque, Marguerite Marie Defebvre, Brigitte Caron, Francois Puisieux, Laurent Plancke
IntroductionOlder adults have one of the highest age‐specific suicide rates in France, and the risk of suicide is higher for those living in nursing homes. The aim of our study was to assess the ef...
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Drug Safety Profiles of Geriatric Patients Referred to Consultation Psychiatry in the Emergency Department—A Retrospective Cohort Study J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-01-02 Martin Schulze Westhoff, Sebastian Schröder, Johannes Heck, Torben Brod, Marcel Winkelmann, Stefan Bleich, Helge Frieling, Kirsten Jahn, Felix Wedegärtner, Adrian Groh
ObjectiveGeriatric patients account for a significant proportion of the collective treated by psychiatric consultation service in hospitals. In the Emergency Department (ED), psychotropic drugs are...
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Impact of PTSD and Obstructive Sleep Apnea on Cognition in Older Adult Veterans J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2023-01-02 Madeline D.W. Noland, Emily W. Paolillo, Art Noda, Laura C. Lazzeroni, Jon-Erik C. Holty, Ware G. Kuschner, Jerome Yesavage, Lisa M. Kinoshita
Background: Posttraumatic stress disorder (PTSD) and obstructive sleep apnea (OSA) are highly prevalent and comorbid among older adult male veterans. Both PTSD and OSA are independently associated ...
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Does Multicomponent Physical Exercise Training Work for Dementia? Exploring the Effects on Cognition, Neuropsychiatric Symptoms, and Quality of Life J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2022-12-27 Flávia Borges-Machado, Laetitia Teixeira, Joana Carvalho, Oscar Ribeiro
ObjectiveTo explore the effects of a multicomponent training (MT) physical exercise intervention in the cognitive function, neuropsychiatric symptoms, and quality of life of older adults with major...
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Understanding Clinician's Experiences with Implementation of a Younger Onset Dementia Telehealth Service J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2022-11-25 Aimee D. Brown, Wendy Kelso, Dennis Velakoulis, Sarah Farrand, Renerus J Stolwyk
The successful implementation of telehealth services depends largely on clinician acceptance of telehealth as a viable healthcare option and their adoption of telehealth methods into their clinical...
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Blood Biomarkers for the Diagnosis of Neurodegenerative Dementia: A Systematic Review J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2022-11-24 Filipa Santos, Verónica Cabreira, Sara Rocha, João Massano
ImportanceAccurately diagnosing neurodegenerative dementia is often challenging due to overlapping clinical features. Disease specific biomarkers could enhance diagnostic accuracy. However, CSF ana...
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Dance-Specific Activity in People Living With Dementia: A Conceptual Framework and Systematic Review of Its Effects on Neuropsychiatric Symptoms J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2022-11-22 Henning Schroeder, Peter Haussermann, Tim Fleiner
ObjectivesDance as a non-pharmacological therapy is commonly used in dementia care, although the evidence of its effects remains unclear. This study systematically reviewed the effects of dance int...
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Caregiver Experiences Navigating the Diagnostic Journey in a Rapidly Progressing Dementia J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2022-11-22 Alissa Bernstein Sideman, Joni Gilissen, Krista L Harrison, Sarah B Garrett, Michael J Terranova, Christine S Ritchie, Michael D Geschwind
IntroductionPeople with suspected Alzheimer’s disease and related dementias (ADRD) and their families experience a burdensome process while seeking a diagnosis. These challenges are problematic in ...
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Demographic and Symptom Correlates of Initial Idiopathic Psychiatric Diagnosis in Frontotemporal Dementia J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2022-11-07 Corinne Sejourne, Jordan D Dworkin, Megan S Barker, Masood Manoochehri, Reena T Gottesman, Eric M Wassermann, Michael C Tierney, Edward D Huey, Jordan Grafman
IntroductionThis study aims to measure frequency and correlates of initial idiopathic psychiatric diagnosis in a cohort of 147 patients with Frontotemporal Dementia (FTD)-spectrum disorders.Methods...
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High frequency of Depressive Disorders and Suicidal Phenomena in Late-Stage Parkinson´s Disease – A Cross-Sectional Study J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2022-10-22 Inês Chendo, Margherita Fabbri, Catarina Godinho, Rita Moiron Simões, Catarina Severiano Sousa, Miguel Coelho, Valerie Voon, Joaquim J. Ferreira
BackgroundDepressive disorders (DD) are widely recognized as one of the most frequent neuropsychiatric disorders in Parkinson´s disease. Patients with late-stage Parkinson´s disease (LSPD) continue...
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The Impact of the COVID-19 Pandemic on Informal Caregivers of People With Parkinson’s Disease Residing in the UK: A Qualitative Study J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2022-10-21 Daniel Rippon, Annette Hand, Lorelle Dismore, Roberta Caiazza
Informal caregivers can experience various demands when providing care and support for People with Parkinson’s disease (PwP) in their own homes. The outbreak of SARS-CoV-2 and public health strateg...
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Breakfast Skipping and Declines in Cognitive Score Among Community-Dwelling Older Adults: A Longitudinal Study of the HEIJO-KYO Cohort J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2022-10-20 Rika Ishizuka, Naoto Otaki, Yoshiaki Tai, Yuki Yamagami, Kunihiko Tanaka, Masayuki Morikawa, Masayuki Iki, Norio Kurumatani, Keigo Saeki, Kenji Obayashi
Previous studies outlined the correlation of adverse effects of breakfast skipping with cognitive function. However, the majority of these studies have focused on the short-term effects; to date, t...
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The Validity of Health-Related Quality of Life Instruments in Patients With Late-Stage Parkinson’s Disease J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2022-10-20 Mouhammed Ramadhan, Anette Schrag, and the CLaSP Consortium
ObjectiveTo examine the validity of health-related quality of life (Hr-QoL) measures in patients with late-stage Parkinson’s disease (PD).MethodsWe analysed data from patients with late-stage PD an...
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Family Carers of People with Dementia in Japan, Spain, and the UK: A Cross-Cultural Comparison of the Relationships between Experiential Avoidance, Cognitive Fusion, and Carer Depression J. Geriatr. Psychiatry Neurol. (IF 2.6) Pub Date : 2022-10-19 Naoko Kishita, Hiroshi Morimoto, María Márquez-González, Samara Barrera-Caballero, Carlos Vara-García, Elien Van Hout, Milena Contreras, Andrés Losada-Baltar
Objective and research design This study investigated whether the relationship between experiential avoidance and carer depression is mediated by cognitive fusion using path analysis and whether th...