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Gender‐related variation expressions of neuroplastin TRAF6, GluA1, GABA(A) receptor, and PMCA in cortex, hippocampus, and brainstem in an experimental epilepsy model Synapse (IF 2.3) Pub Date : 2024-03-04 Züleyha Doğanyiğit, Aslı Okan, Seher Yılmaz, A. Cihangir Uğuz, Enes Akyüz
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Role of M4‐receptor cholinergic signaling in direct pathway striatal projection neurons during dopamine depletion Synapse (IF 2.3) Pub Date : 2024-03-01 Avilés‐Rosas VH, Rendón‐Ochoa EA, Hernández‐Flores T, Flores‐León M, Arias C, Galarraga E, Bargas J
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Liproxstatin-1 alleviates ferroptosis in sevoflurane anesthesia-induced cognitive deficits of aged mice: The role oxidative stress Synapse (IF 2.3) Pub Date : 2024-01-15 Shunyuan Li, Yingle Chen, Yingmei Wang, Xianmei Zhong, Xiaoquan Yu, Zhenming Kang, Yangyi Li
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α7 nicotinic acetylcholine receptors induce long-term synaptic enhancement in the dorsal but not ventral hippocampus Synapse (IF 2.3) Pub Date : 2024-01-08 Giota Tsotsokou, Vasiliki Kouri, Costas Papatheodoropoulos
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Corticotropin-releasing factor-dopamine interactions in male and female macaque: Beyond the classic VTA Synapse (IF 2.3) Pub Date : 2023-11-23 E. A. Kelly, T. M. Love, J. L. Fudge
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Gating small conductance calcium-activated potassium channels in the thalamic reticular nucleus Synapse (IF 2.3) Pub Date : 2023-10-14 Ágata Silván, Kristi Anne Kohlmeier, Kjartan Frisch Herrik, Charlotte Hougaard
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Learning induces EPO/EPOr expression in memory relevant brain areas, whereas exogenously applied EPO promotes remote memory consolidation Synapse (IF 2.3) Pub Date : 2023-10-04 William Almaguer-Melian, Daymara Mercerón-Martinez, Esteban Alberti-Amador, Laura Alacán-Ricardo, Javier Curi de Bardet, Norma Orama-Rojo, Arturo Ernesto Vergara-Piña, Idalia Herrera-Estrada, Jorge A. Bergado
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Quantal size increase induced by the endocannabinoid 2-arachidonoylglycerol requires activation of CGRP receptors in mouse motor synapses Synapse (IF 2.3) Pub Date : 2023-09-11 Ekaterina Tarasova, Polina Bogacheva, Kirill Chernyshev, Olga Balezina
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Autoradiographic characterization of [18F]PSMA-1007 binding in rat brain Synapse (IF 2.3) Pub Date : 2023-07-03 Majken B. Thomsen, Anne M. Landau, Dirk Bender, Paul Cumming
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Relationships of in vivo brain norepinephrine transporter and age, BMI, and gender Synapse (IF 2.3) Pub Date : 2023-06-29 Sheida Koohsari, Faranak Ebrahimian Sadabad, Brian Pittman, Jean-Dominque Gallezot, Richard E. Carson, Christopher H. van Dyck, Chiang-shan R. Li, Marc N. Potenza, David Matuskey
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Date palm spathe extract reverses chronic stress-induced changes in dendritic arborization in the amygdala and impairment of hippocampal long-term potentiation Synapse (IF 2.3) Pub Date : 2023-06-14 Mohammadmehdi Hadipour, Gholam Hossein Meftahi, Gila Pirzad Jahromi
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A systematic review of the local field potential adaptations during conditioned place preference task in preclinical studies Synapse (IF 2.3) Pub Date : 2023-06-06 Mojdeh Fattahi, Shaghayegh Modaberi, Kiarash Eskandari, Abbas Haghparast
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Mechanism of cognitive impairment induced by d-galactose and l-glutamate through gut–brain interaction in tree shrews Synapse (IF 2.3) Pub Date : 2023-05-21 Limei Wang, Jingli Lu, Yi Yang, Yulan Zhao, Peijin Wang, Jianlin Jiao, Hong Zheng
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Synaptic dysfunction in schizophrenia Synapse (IF 2.3) Pub Date : 2023-05-21 Emre Mısır, Güvem Gümüş Akay
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Chronic resveratrol administration reduces oxidative stress and brain cell loss and improves memory of recognition in old rats Synapse (IF 2.3) Pub Date : 2023-05-02 Daniel Juarez, Ivan Arteaga, Haisha Cortes, Ruben Vazquez-Roque, Gustavo Lopez-Lopez, Gonzalo Flores, Samuel Treviño, Jorge Guevara, Alfonso Diaz
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Neonatal olfactory bulbectomy induces anxiety-related behavior and modifies dopaminergic receptor expression in post-pubertal rats Synapse (IF 2.3) Pub Date : 2023-05-02 Gonzalo Flores, María de Jesús Gómez-Villalobos, Tommaso Iannitti, Julio César Morales-Medina
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The role of NMDA glutamate receptors in the lateral habenula on morphine-induced conditioned place preference in rats Synapse (IF 2.3) Pub Date : 2023-04-30 Elahe Amohashemi, Parham Reisi, Hojjatallah Alaei
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The increase of Nrf2 m6A modification induced by FTO downregulation promotes hippocampal neuron injury and aggravates the progression of epilepsy in a rat model Synapse (IF 2.3) Pub Date : 2023-04-30 Mao-Qiang Tian, Juan Li, Xiao-Mei Shu, Chang-Hui Lang, Jing Chen, Long-Ying Peng, Wen-Ting Lei, Chang-Jian Yang
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[11C]PBB3 binding in Aβ(–) or Aβ(+) corticobasal syndrome Synapse (IF 2.3) Pub Date : 2023-03-23 Zsolt Cselényi, Johan Wallin, Jonathan Tjerkoski, Björn Bloth, Samuel Svensson, Inger Nennesmo, Dan Sunnemark, Vesna Jelic, Lars Farde, Per Svenningsson
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Neuroprotective mechanism of human umbilical cord mesenchymal stem cell-derived extracellular vesicles improving the phenotype polarization of microglia via the PI3K/AKT/Nrf2 pathway in vascular dementia Synapse (IF 2.3) Pub Date : 2023-03-20 Pengwei Wang, Tingting Yi, Senlin Mao, Mingjie Li
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Upregulation of SLITRK5 in patients with epilepsy and in a rat model Synapse (IF 2.3) Pub Date : 2023-02-22 Yan Liu, Linming Zhang, Mingda Ai, Di Xia, Hongyu Chen, Ruijing Pang, Rong Mei, Lianmei Zhong, Ling Chen
SLIT and NTRK-like protein-5 (SLITRK5) is one of the six members of SLITRK protein family, which is widely expressed in central nervous system (CNS). In brain, SLITRK5 plays important roles in neurite outgrowth, dendritic branching, neuron differentiation, synaptogenesis, and signal transmission of neurons. Epilepsy is a common, chronic neurological disorder characterized by recurrent spontaneous seizures
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Abnormal [18F]NIFENE binding in transgenic 5xFAD mouse model of Alzheimer's disease: In vivo PET/CT imaging studies of α4β2* nicotinic acetylcholinergic receptors and in vitro correlations with Aβ plaques Synapse (IF 2.3) Pub Date : 2023-02-07 Christopher Liang, Grace A. Nguyen, Tram B. Danh, Anoopraj K. Sandhu, Lusine L. Melkonyan, Amina U. Syed, Jogeshwar Mukherjee
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Spinophilin-dependent regulation of GluN2B-containing NMDAR-dependent calcium influx, GluN2B surface expression, and cleaved caspase expression Synapse (IF 2.3) Pub Date : 2023-02-04 Asma B. Salek, Emily T. Claeboe, Ruchi Bansal, Nicolas F. Berbari, Anthony J. Baucum
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Insulin decreases epileptiform activity in rat layer 5/6 prefrontal cortex in vitro Synapse (IF 2.3) Pub Date : 2023-02-02 N. Villalobos, E. Ramírez-Sánchez, A. Mondragón-García, J. Garduño, D. Castillo-Rolón, S. Trujeque-Ramos, S. Hernández-López
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Adolescence as a critical period for nandrolone-induced muscular strength in relation to abuse liability, alone and in conjunction with morphine, using accumbal dopamine efflux in freely moving rats Synapse (IF 2.3) Pub Date : 2023-01-13 Hiroki Kawashima, Yuri Aono, Shigeki Shimba, John L. Waddington, Tadashi Saigusa
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Triptolide injection reduces Alzheimer's disease-like pathology in mice Synapse (IF 2.3) Pub Date : 2023-01-12 Rui Mao, Shihao Xu, Guangwen Sun, Yingying Yu, Zhiyi Zuo, Yuanyuan Wang, Kun Yang, Zhen Zhang, Wenqiong Yang
Triptolide is an epoxidized diterpene lactone isolated from Tripterygium wilfordii. Studies have shown that triptolide exerts organ-protective effects. However, it remains unknown whether triptolide improves Alzheimer's disease (AD)-like presentations. Thirty healthy 8-week-old male C57BL/6J mice were randomly divided into control (n = 10), model (n = 10), and triptolide (n = 10) groups. Amyloid-β
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Calorie restriction, but not Roux-en-Y gastric bypass surgery, increases [3H] PK11195 binding in a rat model of obesity Synapse (IF 2.3) Pub Date : 2022-11-09 John Hamilton, Cynthia Nguyen, Margaret McAvoy, Nicole Roeder, Brittany Richardson, Teresa Quattrin, Andras Hajnal, Panayotis K. Thanos
Roux-en-Y gastric bypass surgery (RYGB) remains an effective weight-loss method used to treat obesity. While it is successful in combating obesity, there are many lingering questions related to the changes in the brain following RYGB surgery, one of them being its effects on neuroinflammation. While it is known that chronic high-fat diet (HFD) contributes to obesity and neuroinflammation, it remains
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In the parvocellular part of paraventricular nucleus, glutamatergic and GABAergic neurons mediate cardiovascular responses to AngII Synapse (IF 2.3) Pub Date : 2022-10-22 Ali Rastegarmanesh, Bahar Rostami, Ali Nasimi, Masoumeh Hatam
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Tactile stimulation improves cognition, motor, and anxiety-like behaviors and attenuates the Alzheimer's disease pathology in adult APPNL-G-F/NL-G-F mice Synapse (IF 2.3) Pub Date : 2022-10-18 Shakhawat R. Hossain, Hadil Karem, Zahra Jafari, Bryan E. Kolb, Majid H. Mohajerani
Alzheimer's disease (AD) is one of the largest health crises in the world. There are limited pharmaceutical interventions to treat AD, however, and most of the treatment options are not for cure or prevention, but rather to slow down the progression of the disease. The aim of this study was to examine the effect of tactile stimulation (TS) on AD-like symptoms and pathology in APPNL-G-F/NL-G-F mice
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Effects of treadmill exercise and chronic stress on anxiety-like behavior, neuronal activity, and oxidative stress in basolateral amygdala in morphine-treated rats Synapse (IF 2.3) Pub Date : 2022-10-06 Somayeh Shahidani, Zahra Jokar, Hojjatallah Alaei, Parham Reisi
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Kainate receptors GluK1 and GluK2 differentially regulate synapse morphology Synapse (IF 2.3) Pub Date : 2022-09-19 Gui-Fang Duan, Xiao-Hui Tang, Min Jia, Dan Wu, Yun Stone Shi
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Individual differences in the positive outcome from adolescent ketamine treatment in a female mouse model of anorexia nervosa involve drebrin A at excitatory synapses of the medial prefrontal cortex Synapse (IF 2.3) Pub Date : 2022-09-19 Rose Temizer, Yi-Wen Chen, Chiye Aoki
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Dopamine receptor and dopamine transporter in obesity: A meta-analysis Synapse (IF 2.3) Pub Date : 2022-09-13 Kyoungjune Pak, Ju Won Seok, Myung Jun Lee, Keunyoung Kim, In Joo Kim
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Pharmacological characterization and differential expression of NMDA receptor subunits in the chicken vestibular system during development Synapse (IF 2.3) Pub Date : 2022-09-13 Ana Ramírez, Eduardo Monjaraz, Elías Manjarrez, Alejandro Moyaho, Jorge Cebada, Amira Flores
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Developmental light deprivation transiently reduces the expression of vGluT2 and GluN2B in the rat ventral suprachiasmatic nucleus Synapse (IF 2.3) Pub Date : 2022-09-09 Miriam E. Reyes-Méndez, J. Manuel Herrera-Zamora, Fernando Osuna-Lopez, Irving S. Aguilar-Martínez, José L. Góngora-Alfaro, Ricardo A. Navarro-Polanco, Enrique Sánchez-Pastor, Eloy G. Moreno-Galindo, Javier Alamilla
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Acute MPTP treatment decreases dendritic spine density of striatal medium spiny neurons via SNK-SPAR pathway in C57BL/6 mice Synapse (IF 2.3) Pub Date : 2022-08-25 Yebo Su, Miao Jia, Sifan Yuan, Cong Wang, Jiahui Feng, Yumei Zhang
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Role of Bin-Amphiphysin-Rvs (BAR) domain proteins in mediating neuronal signaling and disease Synapse (IF 2.3) Pub Date : 2022-07-23 Bhagaban Mallik, Sajad Bhat, Vimlesh Kumar
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Association between abnormal brain oscillations and cognitive performance in patients with bipolar disorder: Molecular mechanisms and clinical evidence Synapse (IF 2.3) Pub Date : 2022-07-18 Zhou Lu, Huixiao Wang, Jiajie Gu, Feng Gao
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Presynaptic nigral GPR55 receptors stimulate [3H]-GABA release through [3H]-cAMP production and PKA activation and promote motor behavior Synapse (IF 2.3) Pub Date : 2022-07-13 Rodolfo Sánchez-Zavaleta, José Arturo Ávalos-Fuentes, Antonio Valentín González-Hernández, Sergio Recillas-Morales, Francisco Javier Paz-Bermúdez, Gerardo Leyva-Gómez, Hernán Cortés, Benjamín Florán
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Dopamine-transporter heterozygous rats carrying maternal wild-type allele are more vulnerable to the development of compulsive behavior Synapse (IF 2.3) Pub Date : 2022-06-30 Fabiana Festucci, Eugenia Annunzi, Martina Pepe, Giuseppe Curcio, Claudio D'Addario, Walter Adriani
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Abstinence following intermittent methylphenidate exposure dose-dependently modifies brain glucose metabolism in the rat brain Synapse (IF 2.3) Pub Date : 2022-06-21 Eliz Arnavut, John Hamilton, Rutao Yao, Munawwar Sajjad, Michael Hadjiargyrou, David Komatsu, Panayotis K. Thanos
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Effect of cadmium administration on the antioxidant system and neuronal death in the hippocampus of rats Synapse (IF 2.3) Pub Date : 2022-06-16 Samuel Treviño, Guadalupe Pulido, Estefania Fuentes, Anabella Handal-Silva, Albino Moreno-Rodríguez, Berenice Venegas, Gonzalo Flores, Jorge Guevara, Alfonso Díaz
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Decreased 5-HT1A binding in mild Alzheimer's disease-A positron emission tomography study. Synapse (IF 2.3) Pub Date : 2022-05-28 Patrik Mattsson,Zsolt Cselényi,Bengt Andrée,Jacqueline Borg,Sangram Nag,Christer Halldin,Lars Farde
Decreased 5-HT1A receptor binding has been associated with Alzheimer's disease (AD) and interpreted as a consequence of neuron loss. The purpose of the present study was to compare [11 C]WAY100635 binding to the 5-HT1A receptor in the hippocampus, entorhinal cortex, amygdala and pericalcarine cortex in mild AD patients and elderly controls. AD patients (n = 7) and elderly control subjects (n = 8) were
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Decreased 5-HT1A binding in mild Alzheimer's disease—A positron emission tomography study Synapse (IF 2.3) Pub Date : 2022-05-19 Patrik Mattsson, Zsolt Cselényi, Bengt Andrée, Jacqueline Borg, Sangram Nag, Christer Halldin, Lars Farde
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Functions of potassium channels blocked by low micromolar 4-aminopyridine in the crayfish nervous system. Synapse (IF 2.3) Pub Date : 2022-05-01 Nicole Goldfeder,Riley McDonald,Sarah Gaston,Amarri Harrison,Dong-Ho Kim,Clara MacIntosh,Mauricio Moel Miranda,Emma Odom,Simmi Nishad,William Siwik,Liangzhu Zhang,Jen-Wei Lin
4-aminopyridine (4-AP) is a potassium channel blocker that has been used to treat patients with multiple sclerosis and Lambert-Eaton disease. The concentration of this drug in the blood of patients was estimated to be in low or submicromolar range. Animal studies have shown that 4-AP at such low concentration selectively blocks a subset of channels in Kv1 or Kv3 families. The crayfish opener neuromuscular
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Functions of potassium channels blocked by low micromolar 4-aminopyridine in the crayfish nervous system Synapse (IF 2.3) Pub Date : 2022-04-23 Nicole Goldfeder, Riley McDonald, Sarah Gaston, Amarri Harrison, Dong-Ho Kim, Clara MacIntosh, Mauricio Moel Miranda, Emma Odom, Simmi Nishad, William Siwik, Liangzhu Zhang, Jen-Wei Lin
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Effects of selective orexin receptor-2 and cannabinoid receptor-1 antagonists on the response of medial prefrontal cortex neurons to tramadol. Synapse (IF 2.3) Pub Date : 2022-03-29 Neda Hasanpour Razmanjani,Parham Reisi
Tramadol is widely used to control pain in various diseases, but the relevant mechanisms are less known despite the severe risks of abuse. The medial prefrontal cortex (mPFC) is one of the critical centers of the reward system. Studies have shown that orexins and endocannabinoids are likely to play an important role in addiction. In this study, the effect of orexin receptor-2 (OX2R) and endocannabinoid
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Effects of selective orexin receptor-2 and cannabinoid receptor-1 antagonists on the response of medial prefrontal cortex neurons to tramadol Synapse (IF 2.3) Pub Date : 2022-03-21 Neda Hasanpour Razmanjani, Parham Reisi
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Comparative analysis of striatal [18F]FDOPA uptake in a partial lesion model of Parkinson's disease in rats: Ratio method versus graphical model Synapse (IF 2.3) Pub Date : 2022-03-06 Arturo Avendaño-Estrada, Leticia Verdugo-Díaz, Miguel A. Ávila-Rodríguez
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Glutamate potentiates heterologously expressed homomeric acid-sensing ion channel 1a Synapse (IF 2.3) Pub Date : 2022-02-14 Vasilii Shteinikov, Konstantin Evlanenkov, Konstantin Bolshakov, Denis Tikhonov
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Role of Stat3 in NLRP3/caspase-1-mediated hippocampal neuronal pyroptosis in epileptic mice Synapse (IF 2.3) Pub Date : 2021-12-27 Qian Jiang, Guo Tang, Xue-Min Zhong, Dan-Rui Ding, Hui Wang, Jia-Ni Li
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Does astrocyte gap junction protein expression differ during development in absence epileptic rats? Synapse (IF 2.3) Pub Date : 2022-02-08 Büşra Köse, Mazhar Özkan, İlknur Sur-Erdem, Safiye Çavdar
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Limited power of dopamine transporter mRNA mapping for predicting dopamine transporter availability Synapse (IF 2.3) Pub Date : 2022-02-01 Kyoungjune Pak, Seongho Seo, Myung Jun Lee, Hyung-Jun Im, Keunyoung Kim, In Joo Kim
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SLC6A3 gene polymorphisms are associated with striatal dopamine transporter changes after glucose loading Synapse (IF 2.3) Pub Date : 2022-01-31 Kyoungjune Pak, Seongho Seo, Keunyoung Kim, Myung Jun Lee, In Joo Kim
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Endosomal recycling and dopamine neurotransmission: Exploring the links between the retromer and Parkinson's disease Synapse (IF 2.3) Pub Date : 2022-01-26 Nathan Gock, Jordan Follett, Gordon L Rintoul, Timothy V Beischlag, Frank J.S. Lee
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Asymmetrical organization of oral structures in the primary and secondary somatosensory cortices in rats: An optical imaging study Synapse (IF 2.3) Pub Date : 2022-01-16 Yuki Kirihara, Manabu Zama, Satoshi Fujita, Shouhei Ogisawa, Shuichi Nishikubo, Morio Tonogi, Masayuki Kobayashi
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Sensitivity of subcellular components of neuromuscular junctions to decreased neuromuscular activity Synapse (IF 2.3) Pub Date : 2021-07-28 Michael R. Deschenes, Audrey M. Trebelhorn, Madeline C. High, Hannah L. Tufts, Jeongeun Oh
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Acute Delta 9-tetrahydrocannabinol administration differentially alters the hippocampal opioid system in adult female and male rats Synapse (IF 2.3) Pub Date : 2021-07-13 Kyle A. Windisch, Sanoara Mazid, Megan A. Johnson, Elina Ashirova, Yan Zhou, Lennox Gergoire, Sydney Warwick, Bruce S. McEwen, Mary Jeanne Kreek, Teresa A. Milner