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COMPLIMENTS TO SHAIDA ET AL. IN DESCRIBING SWELLING OVER COCHLEAR IMPLANT RECEIVER-STIMULATOR PACKAGE: MOREL-LAVALLÉE IS LIKELY AN ETIOLOGIC MECHANISM. Otol. Neurotol. (IF 2.1) Pub Date : 2023-12-01 Melissa S Oh,Nandini Govil,Kristan Alfonso,Norman Wendell Todd
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Exoscope-Assisted Stapedotomy: Evaluation of Safety and Efficacy. Otol. Neurotol. (IF 2.1) Pub Date : 2023-12-01 Robert M Conway,Caleb J Fan,Jonathan S Choi,Kavan Babu,Hugh P Mallany,Seilesh C Babu
OBJECTIVE Evaluate the safety and efficacy of exoscope-assisted stapedotomy. STUDY DESIGN Retrospective chart review. SETTING Tertiary care neurotology clinic. PATIENTS Adult patients with otosclerosis undergoing stapedotomy. INTERVENTIONS Primary stapedotomy. MAIN OUTCOME MEASURES Evaluation of audiologic outcomes, including pure-tone average, bone-conduction thresholds, word recognition score, and
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Comparison of Speech Recognition and Hearing Preservation Outcomes Between the Mid-Scala and Lateral Wall Electrode Arrays. Otol. Neurotol. (IF 2.1) Pub Date : 2023-11-27 Ankita Patro,Nathan R Lindquist,Natalie Schauwecker,Jourdan T Holder,Elizabeth L Perkins,David S Haynes,Kareem O Tawfik
OBJECTIVE To assess speech recognition and hearing preservation (HP) outcomes with the Advanced Bionics Mid-Scala and SlimJ electrodes. STUDY DESIGN Retrospective cohort. SETTING Tertiary referral center. PATIENTS A total of 237 adult patients implanted between 2013 and 2020 (Mid-Scala, n = 136; SlimJ, n = 101). MAIN OUTCOME MEASURES Consonant-nucleus-consonant (CNC) and AzBio (Arizona Biomedical)
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Quantification of Mastoid Air Cells and Opacification of the Middle Ear in Primary Ciliary Dyskinesia. Otol. Neurotol. (IF 2.1) Pub Date : 2023-11-17 Eri Nishida,Hiroshi Sakaida,Masako Kitano,Kazuhiko Takeuchi
OBJECTIVE To evaluate pneumatization and opacification of the temporal bone on computed tomography (CT) images in patients with primary ciliary dyskinesia (PCD). STUDY DESIGN Retrospective case-control study. SETTING Tertiary referral center. PATIENTS Fifteen patients with PCD (30 ears) and 45 age-matched individuals without PCD (90 ears) as controls. INTERVENTION Diagnostic only. MAIN OUTCOME MEASURES
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Investigating Deferral Rates in Cochlear Implantation: How Often Do Candidates Defer and Why? Otol. Neurotol. (IF 2.1) Pub Date : 2023-11-17 Vivian F Kaul,Bryce P G Dzubara,Vikas Munjal,Juhi Katta,Oliver F Adunka,Yin Ren
OBJECTIVE Evaluate the rate at which cochlear implant (CI) candidates decline surgery and identify associated factors. STUDY DESIGN Retrospective cohort study. SETTING Tertiary referral center. PATIENTS Four hundred ninety-three CI candidates from July 1989 to December 2020 with complete demographic and socioeconomic data. INTERVENTIONS Diagnostic. MAIN OUTCOME MEASURES Age, sex, race, marital and
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Posterior Canal Fibrosis: A Case Series. Otol. Neurotol. (IF 2.1) Pub Date : 2023-11-17 Abel P David,Camilo Bolds,Xin Wu,Jeffrey D Sharon
OBJECTIVE To establish a case series where loss of magnetic resonance fluid signal intensity in the posterior semicircular canal (SCC) corresponded with a functional deficit on clinical and video head impulse testing, and most likely a result of canal fibrosis or obstruction. PATIENTS Three patients with an magnetic resonance imaging (MRI) showing loss of T2-weighted signal intensity in their posterior
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Characterization of Vestibular Perception in Patients with Persistent Postural-Perceptual Dizziness. Otol. Neurotol. (IF 2.1) Pub Date : 2023-11-17 Megan J Kobel,Andrew R Wagner,John G Oas,Daniel M Merfeld
OBJECTIVE To assess vestibular (i.e., passive self-motion) perception in patients diagnosed with persistent postural-perceptual dizziness (PPPD). STUDY DESIGN Case-controlled, cross-sectional, observational investigation. SETTING Single-center laboratory-based study. PATIENTS Thirteen patients with PPPD, 13 age-matched healthy control volunteers. Of those with PPPD, eight had co-occurring vestibular
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Systematic Review of Intracochlear Measurements and Effect on Postoperative Auditory Outcomes after Cochlear Implant Surgery. Otol. Neurotol. (IF 2.1) Pub Date : 2023-11-10 Zubair Hasan,Seraphina Key,Michael Lee,Melville Da Cruz
OBJECTIVE Quality and adequacy of the electrode neuron interface (ENI) is postulated to be a determining factor in affecting auditory outcomes after cochlear implantation. This study aims to review radiological parameters affecting ENI, including angular insertion (AngI), wrapping factor (WF), scalar translocation (ScaT), and electrode-modiolar distance (EMD) and their effect on auditory outcomes.
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High-Frequency Gain and Maximum Output Effects on Speech Recognition in Bone-Conduction Hearing Devices: Blinded Study. Otol. Neurotol. (IF 2.1) Pub Date : 2023-11-02 Tyuana Sandim da Silveira Sassi,Erika Cristina Bucuvic,Eliane Aparecida Techi Castiquini,Juliana Nogueira Chaves,Marcia Kimura,Byanka Cagnacci Buzo,Luiz Fernando Manzoni Lourençone
INTRODUCTION Bone-conduction hearing device (BCHD) uses natural sound transmission through bone and soft tissue, directly to the cochlea, via an external processor that captures and processes sound, which is converted into mechanical vibrations. Key parameters, as maximum power output (MPO) and broader frequency range (FR), must be considered when indicating a BCHD because they can be decisive for
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A Multicenter Comparison of 1-yr Functional Outcomes and Programming Differences Between the Advanced Bionics Mid-Scala and SlimJ Electrode Arrays. Otol. Neurotol. (IF 2.1) Pub Date : 2023-10-27 Susan T Eitutis,Deborah A Vickers,Karen Tebbutt,Tisa Thomas,Dan Jiang,Anel de Klerk,Jennifer Clemesha,Mark Chung,Manohar L Bance
OBJECTIVE To determine if there is a difference in hearing outcomes or stimulation levels between Advanced Bionics straight and precurved arrays. STUDY DESIGN Retrospective chart review across three implant centers. SETTING Tertiary centers for cochlear and auditory brainstem implantation. PATIENTS One hundred fifteen pediatric and 205 adult cochlear implants (CIs) were reviewed. All patients were
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Perceptions Surrounding Cochlear Implants Among At-Risk and Qualifying Older Adults in the United States. Otol. Neurotol. (IF 2.1) Pub Date : 2023-10-25 Matthew L Carlson,Christine M Lohse,John P Marinelli,Sarah A Sydlowski,Hearing Health Collaborative
OBJECTIVE Limited evidence to date has examined public perceptions of cochlear implants among adult hearing aid users with moderate to profound hearing loss. The current work was conceived with the chief objective of characterizing the perceptions surrounding cochlear implants among the prospective candidate pool. STUDY DESIGN National cross-sectional survey study. SETTING United States. PATIENTS Adults
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Rationale for the Development of a Novel Clinical Grading Scale for Postoperative Facial Nerve Function: Results of a Multidisciplinary International Working Group. Otol. Neurotol. (IF 2.1) Pub Date : 2023-10-25 Matthew L Carlson,Christine M Lohse,Siviero Agazzi,Seilesh C Babu,Frederick G Barker,Samuel Barnett,Wenya Linda Bi,Nigel Biggs,Kofi D Boahene,Joseph T Breen,Kevin D Brown,Per Cayé-Thomasen,Maura K Cosetti,Nicholas L Deep,Jacob K Dey,James R Dornhoffer,David Forner,Richard K Gurgel,Marlan R Hansen,Jacob B Hunter,Michel Kalamarides,Irene A Kim,Andrew T King,Matthew L Kircher,Luis Lassaletta,Michael J
OBJECTIVE The objective of the current study was to present the results of an international working group survey identifying perceived limitations of existing facial nerve grading scales to inform the development of a novel grading scale for assessing early postoperative facial paralysis that incorporates regional scoring and is anchored in recovery prognosis and risk of associated complications. STUDY
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Comparing Speech Recognition Outcomes Between Cochlear Implants and Auditory Brainstem Implants in Patients With NF2-Related Schwannomatosis. Otol. Neurotol. (IF 2.1) Pub Date : 2023-10-25 James R Dornhoffer,Aaron R Plitt,Christine M Lohse,Colin L W Driscoll,Brian A Neff,Aniket A Saoji,Jamie J Van Gompel,Michael J Link,Matthew L Carlson
OBJECTIVE To compare cochlear implant (CI) and auditory brainstem implant (ABI) performance in patients with NF2-related schwannomatosis (NF2). STUDY DESIGN Historical cohort. SETTING Tertiary academic center. PATIENTS A total of 58 devices among 48 patients were studied, including 27 ABIs implanted from 1997 to 2022 and 31 CIs implanted from 2003 to 2022. Three patients had bilateral ABIs, three had
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Post Cochlear Implantation Vertigo: Ictal Nystagmus and Audiovestibular Test Characteristics. Otol. Neurotol. (IF 2.1) Pub Date : 2023-10-19 Belinda Y C Kwok,Allison S Young,Jonathan H K Kong,Catherine S Birman,Sean Flanagan,Simon L Greenberg,William P Gibson,Emma C Argaet,Luke Fratturo,Jacob M Pogson,Rachael L Taylor,Sally M Rosengren,G Michael Halmagyi,Miriam S Welgampola
OBJECTIVE To investigate ictal nystagmus and audiovestibular characteristics in episodic spontaneous vertigo after cochlear implantation (CI). STUDY DESIGN Retrospective and prospective case series. PATIENTS Twenty-one CI patients with episodic spontaneous vertigo after implantation were recruited. INTERVENTIONS Patient-initiated home video-oculography recordings were performed during one or more attacks
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Association of Smoke and Nicotine Product Consumption With Sensorineural Hearing Loss: A Population-Level Analysis. Otol. Neurotol. (IF 2.1) Pub Date : 2023-10-19 Marwin Li,Natalie M Perlov,Jena Patel,Dev Amin,Ayan Kumar,Zachary D Urdang,Thomas O Willcox,Rebecca C Chiffer
OBJECTIVE To test the hypothesis that use of cigarettes or other products with either cigarette-like smoke profile or high nicotine content by young populations increases the odds of developing sensorineural hearing loss (SNHL). STUDY DESIGN Retrospective cohort study. SETTING TriNetX US Collaborative Network (2003-2022). PATIENTS Approximately 3.6 million patients at least 18 years old. INTERVENTION
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Predictive Factors for Subjective Vertigo Following Cochlear Implantation: A Regional Multicenter Cohort Study of 395 Patients. Otol. Neurotol. (IF 2.1) Pub Date : 2023-10-19 Isabella Ludbrook,Manish Mair,Daniel Phung,Toby Corlette,Johnson Huang,Kelvin Kong Worimi,Robert Eisenberg
INTRODUCTION Cochlear implantation (CI) is generally accepted as having a low rate of postoperative complications, but between 9.3% and 13% of cases experience vertigo postoperatively. This study aimed to examine patient, surgical, and device factors contributing toward the risk of postoperative vertigo. METHODOLOGY A retrospective review was conducted of adult patients who underwent cochlear implant
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Indications of Effective Hyperbaric Oxygen Therapy Combined With Steroid Therapy for Sudden Hearing Loss. Otol. Neurotol. (IF 2.1) Pub Date : 2023-10-19 Shinya Ohira,Manabu Komori,Yukari Tsuna,Mitsuto Nakamura,Yusei Yamaguchi,Kentaro Matsuura,Hiroshi Osafune,Kota Wada
OBJECTIVE This study evaluated the therapeutic effect of hyperbaric oxygen therapy (HBOT) combined with steroid therapy to treat sudden hearing loss and examined the index associated with excellent therapeutic effect. METHODS We included 109 patients with sudden hearing loss. Patients were divided into the HBOT combination group (59 sides) treated with HBOT and steroid therapy and HBOT noncombination
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Determinants of Cochlear Implant Satisfaction and Decisional Regret in Adult Cochlear Implant Users. Otol. Neurotol. (IF 2.1) Pub Date : 2023-10-19 Christian M Shannon,Kara C Schvartz-Leyzac,Judy R Dubno,Theodore R McRackan
OBJECTIVE Determine associations expected and actual cochlear implant (CI) outcomes, decisional regret, and satisfaction in experienced adult CI users. STUDY DESIGN Cross-sectional cohort study. SETTING Tertiary medical center. PATIENTS Thirty-nine adult CI users meeting traditional bilateral hearing loss indications with ≥12 months CI experience. INTERVENTIONS/MAIN OUTCOME MEASURES Patients completed
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Characteristics and Management of Facial Nerve Schwannomas and Hemangiomas. Otol. Neurotol. (IF 2.1) Pub Date : 2023-10-19 Manjunath Dandinarasaiah,Golda Grinblat,Venkatesha Belur Keshavamurthy,Vittoria M Di Rubbo,Russo Alessandra,Lorenzo Lauda,Mario Sanna
OBJECTIVES To characterize facial nerve (FN) schwannomas (FNSs) and FN hemangiomas (FNHs) and their clinical features and management strategies, and to describe the results of cable nerve grafting after FN sectioning during tumor removal. METHODS This retrospective study included 84 FNS cases and 42 FNH cases managed between July 1989 and July 2020 at a quaternary referral center for skull base pathology
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Temporal Trends in Early Pediatric Cochlear Implantations in California from 2018 to 2020. Otol. Neurotol. (IF 2.1) Pub Date : 2023-10-19 Rance J T Fujiwara,Emily C Wong,Gail Ishiyama,Akira Ishiyama
OBJECTIVE To characterize the demographics of children receiving cochlear implantations, identify factors associated with delayed implantations, and trend these factors over time. DESIGN Retrospective cross-sectional study. SETTING Healthcare Cost and Utilization Project California State Ambulatory Surgery Database for calendar years 2018-2020. PATIENTS Children 5 years or younger undergoing cochlear
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Identification of Risk Factors for Mortality and Prolonged Hospitalization in Patients Treated With Surgical Drainage for Otogenic Intracranial Complications: A Nationwide Study Using a Japanese Inpatient Database. Otol. Neurotol. (IF 2.1) Pub Date : 2023-10-19 Hiroshi Hidaka,Kunio Tarasawa,Kenji Fujimori,Taku Obara,Kiyohide Fushimi,Akihiro Shimamura,Hiroshi Iwai
OBJECTIVE Data on risk factors for otogenic intracranial complications including cerebral abscess have been limited. Using a nationwide database, the aim was to identify the factors related to mortality and delayed discharge. STUDY DESIGN Retrospective. SETTING Nationwide database using the Diagnostic Procedure Combination database. MAIN OUTCOME MEASURES Data of 145 patients were extracted from a Japanese
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Initial Response to Combination Therapies for Tinnitus: Lessons Learned From a Retrospective Analysis. Otol. Neurotol. (IF 2.1) Pub Date : 2023-10-19 Seung-Ho Shin,Sung Wan Byun,Ho Yun Lee
OBJECTIVE To investigate the initial reduction of tinnitus effects by combining common therapies applicable in general otology clinics and establishing optimal treatment strategies. STUDY DESIGN Retrospective cohort study. SETTING A tertiary university hospital. PATIENTS Patients with nonpulsatile subjective tinnitus who visited the hospital between January and December 2022. INTERVENTIONS Combination
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Cytokine Profiling of Cyst Fluid and Tumor-Associated Macrophages in Cystic Vestibular Schwannoma. Otol. Neurotol. (IF 2.1) Pub Date : 2023-10-19 Eric Nisenbaum,Matthew Wiefels,Julia Telischi,Mikhail Marasigan,Vivek Kanumuri,Stefanie Pena,Torin Thielhelm,Olena Bracho,Rita Bhatia,Tricia Scaglione,Fred Telischi,Cristina Fernandez-Valle,Xue-Zhong Liu,Evan Luther,Jacques Morcos,Michael Ivan,Christine T Dinh
BACKGROUND The vestibular schwannoma (VS) secretome can initiate monocyte recruitment and macrophage polarization to M1 (proinflammatory) and/or M2 (protumorigenic) phenotypes, which in turn secrete additional cytokines that contribute to the tumor microenvironment. Profiling cyst fluid and cerebrospinal fluid (CSF) in cystic VS provides a unique opportunity to understand mechanisms that may contribute
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The Significance of Bell's Palsy That Presents as Monocranial Versus Polycranial Neuropathy: A Case Series and Systematic Literature Review. Otol. Neurotol. (IF 2.1) Pub Date : 2023-10-13 Oren Ziv,Chen Hazout,Nitzan Goldberg,Alex Tavdi,Ariel Zholkovsky,Sofia Kordeluk,Sabri El-Saied,Anat Bahat Dinur,Joshua Ben-Zion,Nidal Muhanna,Omer J Ungar
PURPOSE To investigate the effect of Bell's palsy (BP) presenting as polycranial neuropathy (PCN) compared with BP caused by isolated facial nerve (CNVII). METHODS We carried out a retrospective cohort study of the medical records of all consecutive patients who were diagnosed with BP at a single tertiary referral center between 2010 and 2017. Included were patients 18 years or older who were clinically
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Correlation Between Quality of Life and Speech Recognition Outcomes Following Cochlear Implantation. Otol. Neurotol. (IF 2.1) Pub Date : 2023-10-10 Christina Dorismond,Ankita Patro,Jourdan T Holder,Elizabeth L Perkins
OBJECTIVE To study the relationship between Cochlear Implant Quality of Life-10 Global (CIQOL-10) scores and speech recognition scores 6 and 12 months after cochlear implantation (CI) and to compare CIQOL-10 scores for patients who met the benchmark speech recognition scores with those who did not. STUDY DESIGN Retrospective review. SETTING Tertiary referral center. PATIENTS One hundred twenty-four
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The Validation of a Simultaneous Ocular and Cervical VEMP Recording Protocol to Unilateral AC Stimuli. Otol. Neurotol. (IF 2.1) Pub Date : 2023-10-10 Luca Verrecchia,Karl-Johan Fredén Jansson,Sabine Reinfeldt,Bo Håkansson
INTRODUCTION A simultaneous recording of cervical and ocular vestibular evoked myogenic potential (sVEMP) to unilateral air-conducted (AC) stimulation reduces the test time and halves the sound load. MATERIALS AND METHODS The sVEMP has been compared with the conventional sequential unilateral AC cervical and ocular VEMP in a consecutive cohort of 120 subjects attending the vestibular laboratory. The
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Longitudinal Patient Outcomes in Chronic Dizziness: A Scoping Review. Otol. Neurotol. (IF 2.1) Pub Date : 2023-10-01 Toros Canturk,Anand K Bery,David Piccoli,Jacob Pyche,Daniel Czikk,Jake Osborne,Alexander Pearson,Chirayu Bhatt,John Shin,Linda Chow,Jayson Lee Azzi,Angelina Tohme,Lisa Caulley,Daniel Lelli,Darren Tse
BACKGROUND Chronic dizziness can cause significant functional impairment. Outcome measures used in this patient population have not been examined systematically. Consequently, providers lack consensus on the ideal outcome measures to assess the impact of their interventions. OBJECTIVE AND METHODS We conducted a scoping review to summarize existing literature on outcomes in chronic dizziness (with a
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Acute and Longer-Term Effects of COVID-19 on Auditory and Vestibular Symptoms. Otol. Neurotol. (IF 2.1) Pub Date : 2023-09-29 Ashley A Berlot,Howard S Moskowitz,Juan Lin,Jianyou Liu,Esha Sehanobish,Elina Jerschow,Thomas J Ow,Elyse S Sussman
OBJECTIVE To evaluate long-term effects of COVID-19 on auditory and vestibular symptoms in a diverse cohort impacted by the initial 2020 COVID-19 infection in the pandemic's epicenter, before vaccine availability. STUDY DESIGN Cohort study of individuals with confirmed COVID-19 infection, diagnosed in the March-May 2020 infection wave. A randomized, retrospective chart review of 1,352 individuals was
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The Impact of Musical Rehabilitation on Complex Sound Perception in Cochlear Implant Users: A Systematic Review. Otol. Neurotol. (IF 2.1) Pub Date : 2023-09-28 Hasan Abdulbaki,Jonathan Mo,Charles J Limb,Nicole T Jiam
OBJECTIVE Musical rehabilitation has been used in clinical and nonclinical contexts to improve postimplantation auditory processing in implanted individuals. This systematic review aimed to evaluate the efficacy of music rehabilitation in controlled experimental and quasi-experimental studies on cochlear implant (CI) user speech and music perception. DATABASES REVIEWED PubMed/MEDLINE, EMBASE, Web of
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Evaluation of Parental Perspectives and Concerns about Pediatric Cochlear Implantation: A Social Media Analysis. Otol. Neurotol. (IF 2.1) Pub Date : 2023-09-28 Emily Y Huang,Tai K Hairston,Jonathan Walsh,Megan E Ballard,Emily F Boss,Carolyn M Jenks
OBJECTIVE Parents often experience uncertainty during decision-making for their child's cochlear implantation (CI) surgery, and online forums provide insight on parental opinions that might not be expressed in clinic. This study aims to evaluate parental perspectives and concerns about pediatric CI using social media analysis. STUDY DESIGN Qualitative study. SETTING Three online forums involving parental
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Incidence of Cochlear Implant Electrode Contacts in the Functional Acoustic Hearing Region and the Influence on Speech Recognition with Electric-Acoustic Stimulation. Otol. Neurotol. (IF 2.1) Pub Date : 2023-09-28 Evan P Nix,Nicholas J Thompson,Kevin D Brown,Matthew M Dedmon,A Morgan Selleck,Andrea B Overton,Michael W Canfarotta,Margaret T Dillon
OBJECTIVES To investigate the incidence of electrode contacts within the functional acoustic hearing region in cochlear implant (CI) recipients and to assess its influence on speech recognition for electric-acoustic stimulation (EAS) users. STUDY DESIGN Retrospective review. SETTING Tertiary referral center. PATIENTS One hundred five CI recipients with functional acoustic hearing preservation (≤80
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National Trends in Cochlear Implantation Across the Department of the Defense: A Case for Inclusion as a General Otolaryngology Core Competency. Otol. Neurotol. (IF 2.1) Pub Date : 2023-09-20 Jason K Adams,John P Marinelli,Russell W DeJong,Samuel A Spear,Isaac D Erbele
OBJECTIVE With ongoing national expansions in cochlear implantation (CI) candidacy criteria, more patients qualify for CI today than ever before. Among US veterans and military service members, the prevalence of qualifying degrees of hearing loss secondary to occupational noise exposure exceeds the general population. The primary aim of the current work was to evaluate CI trends across the military
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Discrepancies Between Expected and Actual Cochlear Implant-Related Functional Outcomes. Otol. Neurotol. (IF 2.1) Pub Date : 2023-09-20 Joshua E Fabie,Christian M Shannon,Kara Schvartz-Leyzac,Judy R Dubno,Theodore R McRackan
OBJECTIVE Previous research has demonstrated that realistic patient expectations are a critical factor in determining cochlear implant (CI) candidacy. The current study uses the validated Cochlear Implant Quality of Life-Expectations (CIQOL-Expectations) instrument to determine expectations of potential CI users and the degree to which their pre-CI expectations are met after implantation. STUDY DESIGN
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Emerging Mechanisms in the Pathogenesis of Menière's Disease: Evidence for the Involvement of Ion Homeostatic or Blood-Labyrinthine Barrier Dysfunction in Human Temporal Bones. Otol. Neurotol. (IF 2.1) Pub Date : 2023-09-20 J Dixon Johns,Rafal Olszewski,Dillon Strepay,Ivan A Lopez,Akira Ishiyama,Michael Hoa
HYPOTHESIS Analysis of human temporal bone specimens of patients with Menière's disease (MD) may demonstrate altered expression of gene products related to barrier formation and ionic homeostasis within cochlear structures compared with control specimens. BACKGROUND MD represents a challenging otologic disorder for investigation. Despite attempts to define the pathogenesis of MD, there remain many
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Middle Ear Mycetoma in a Case of Refractory Chronic Otitis Media. Otol. Neurotol. (IF 2.1) Pub Date : 2023-09-20 De'Andre A Warren,Erica Steele-Bomeisl,Sarah Mowry
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Incidence of Hearing Loss in Corpus Callosum Agenesis. Otol. Neurotol. (IF 2.1) Pub Date : 2023-09-20 Jayoon Kim,Mincheol Jeong,Seungjoon Yang,Jung Ho Han,Seong Hoon Bae
OBJECTIVES Congenital corpus callosum agenesis (CCA) is one of the congenital anomalies in newborns, which usually presents with syndromic features. It can be asymptomatic or have variable neurological deficits. Some studies demonstrated that hearing loss can occur in patients with CCA; however, the exact prevalence remains unclear. Therefore, we aimed to investigate the prevalence of hearing loss
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Two Discrete Types of Tip Fold-Over in Cochlear Implantation Using Slim Modiolar Electrodes: Influence of Cochlear Duct Length on Tip Fold-Over. Otol. Neurotol. (IF 2.1) Pub Date : 2023-09-20 Heonjeong Oh,Yehree Kim,Seung Jae Lee,Marge Carandang,Jae-Jin Song,Byung Yoon Choi
OBJECTIVE Precise electrode positioning is crucial for achieving optimal audiological outcomes in cochlear implantation. The slim modiolar electrode (SME), a thin, flexible, and precurved electrode, exhibits favorable modiolar proximity. However, tip fold-over can affect optimal electrode placement. Herein, we share our experiences with tip fold-over in SMEs and present an analysis of conditions that
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Diagnostic Efficacy of High-Resolution Computed Tomography Densitometry for Diagnosing Otosclerosis. Otol. Neurotol. (IF 2.1) Pub Date : 2023-09-20 Ignacio Viza Puiggrós,Esther Granell Moreno,César Orús Dotu,Miquel Quer I Agustí,Francesc Larrosa Díaz
OBJECTIVES The purpose of this study is to evaluate the reliability of temporal bone density measurements for diagnosing otosclerosis. MATERIALS AND METHODS A retrospective case-control study is presented. Bone density was measured in Hounsfield units (HUs) by using high-resolution computed tomography in eight regions of interest (ROI) where otosclerotic foci are usually localized. The density of 113
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Electrode-Modiolus Distance Affects Speech Perception for Lateral Wall Electrodes. Otol. Neurotol. (IF 2.1) Pub Date : 2023-09-19 Ling Ding,Luguang Zhang,Jing Li,Tao Lin
OBJECTIVES The goal of this study was to use cone-beam computed tomography to locate the electrode-modiolus distance (EMD) and correlate this with speech perception in cochlear implant (CI) recipients of the 31.5-mm lateral wall (LW) electrode arrays. STUDY DESIGN Retrospective review. PATIENTS Forty-five child CI recipients with prelingual profound sensorineural hearing loss of inserted 31.5-mm LW
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Correlating Vestibular Migraine Patient Assessment Tool and Handicap Inventory to Daily Dizziness Symptoms. Otol. Neurotol. (IF 2.1) Pub Date : 2023-09-15 Eric K Kim,Maxwell Hum,Jeffrey D Sharon
OBJECTIVE Investigate the relationship between Vestibular Migraine Patient Assessment Tool and Handicap Inventory (VM-PATHI) scores and daily dizziness symptoms. STUDY DESIGN Prospective cohort analysis of 52 patients with vestibular migraine (VM). SETTING Tertiary referral center. PATIENTS Fifty-two patients diagnosed with VM or probable VM according to Barany Society criteria. INTERVENTIONS Subjects
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Fibroblasts Derived From Vestibular Schwannoma Express Protumorogenic Markers. Otol. Neurotol. (IF 2.1) Pub Date : 2023-09-15 Paramita Baruah,Jennifer Marshall,Philip N Jones,Triin Major,Valentina Pucino,John D O'Neil,Meriam Nefla,Helen McGettrick,Peter Monksfield,Richard Irving,Christopher D Buckley
BACKGROUND AND AIM Vestibular schwannomas (VSs), despite being histologically benign, cause significant morbidity because of their challenging intracranial location and the propensity for growth. The role of the stroma and particularly fibroblasts, in the progression of VS, is not completely understood. This study examines the profile of fibroblasts in VS. METHODS Seventeen patients undergoing surgical
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Factors Affecting Performance in Adults With Cochlear Implants: A Role for Cognition and Residual Cochlear Function. Otol. Neurotol. (IF 2.1) Pub Date : 2023-09-15 Amit Walia,Matthew A Shew,Shannon M Lefler,Amanda J Ortmann,Nedim Durakovic,Cameron C Wick,Jacques A Herzog,Craig A Buchman
OBJECTIVE To evaluate the impact of preoperative and perioperative factors on postlinguistic adult cochlear implant (CI) performance and design a multivariate prediction model. STUDY DESIGN Prospective cohort study. SETTING Tertiary referral center. PATIENTS AND INTERVENTIONS Two hundred thirty-nine postlinguistic adult CI recipients. MAIN OUTCOME MEASURES Speech-perception testing (consonant-nucleus-consonant
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Translabyrinthine Craniotomy Is Associated with Higher Risk of Asymptomatic Dural Venous Sinus Thrombosis in Vestibular Schwannoma Resection. Otol. Neurotol. (IF 2.1) Pub Date : 2023-09-06 Hunter L Elms,David M Straka,Dina K Abouelella,Howard W Francis,David M Kaylie,Calhoun D Cunningham
OBJECTIVE Characterize the incidence, risk factors, and patient outcomes of dural venous sinus thrombosis identified on postoperative imaging after retrosigmoid or translabyrinthine craniotomy for vestibular schwannoma resection. STUDY DESIGN Retrospective cohort study. SETTING Single tertiary academic referral center. PATIENTS Eighty-one patients 19 to 82 years of age with vestibular schwannomas,
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Aphasia as Presenting Symptom of Left Temporal Pneumocephalus After a Restrained Sneeze. Otol. Neurotol. (IF 2.1) Pub Date : 2023-08-29 Oghomwen E Ogbeide-Latario,Judith Kempfle,Farid Hamzei-Sichani,Aaron K Remenschneider
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Metformin Protects Against Noise-Induced Hearing Loss in Male Mice. Otol. Neurotol. (IF 2.1) Pub Date : 2023-08-29 Catherine L Kennedy,Benjamin Shuster,Reza Amanipour,Beatrice Milon,Priya Patel,Ran Elkon,Ronna Hertzano
HYPOTHESIS Metformin treatment will protect mice from noise-induced hearing loss (NIHL). BACKGROUND We recently identified metformin as the top-ranking, Food and Drug Administration-approved drug to counter inner ear molecular changes induced by permanent threshold shift-inducing noise. This study is designed to functionally test metformin as a potential otoprotective drug against NIHL. METHODS Male
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Effects of Early Vestibular Rehabilitation in Patients With Acute Vestibular Disorder: A Systematic Review and Meta-Analysis. Otol. Neurotol. (IF 2.1) Pub Date : 2023-08-29 Tomohiko Kamo,Hirofumi Ogihara,Masato Azami,Ryo Momosaki,Hiroaki Fushiki
OBJECTIVES To investigate the effect of early vestibular rehabilitation on physical function and dizziness in patients with acute vestibular disorders. DATABASES REVIEWED The electronic databases examined included PubMed (MEDLINE), Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE (via Dialog), and PEDro. METHODS The inclusion criteria in terms of the study participants were patients
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Prosthetic Stimulation of the Vestibular Nerve Can Evoke Robust Eye and Head Movements Despite Prior Labyrinthectomy. Otol. Neurotol. (IF 2.1) Pub Date : 2023-08-28 Kantapon Pum Wiboonsaksakul,Charles C Della Santina,Kathleen E Cullen
HYPOTHESIS Prosthetic electrical stimulation can evoke compensatory eye and head movement despite vestibular implant electrode insertion occurring years after prior labyrinthectomy. BACKGROUND Vestibular implants sense head rotation and directly stimulate the vestibular nerve, bypassing damaged end organs. Animal research and current clinical trials have demonstrated the efficacy of this approach.
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Transmastoid Facial Nerve Decompression for Craniometaphyseal Dysplasia. Otol. Neurotol. (IF 2.1) Pub Date : 2023-08-26 Andrew S Lee,Bing M Teh,George Alexiades
OBJECTIVE We document the first successful transmastoid surgical treatment of facial nerve palsy for a patient with craniometaphyseal dysplasia (CMD), a rare genetic disease. PATIENT A 9-month-old girl with bilateral facial nerve palsies and conductive hearing loss. Genetic testing made a diagnosis of CMD, and imaging showed narrowing of the facial nerve canals and ossicular fixation. INTERVENTION
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The Dependency of Cochlear Lateral Wall Measurements on Observer and Imaging Type. Otol. Neurotol. (IF 2.1) Pub Date : 2023-08-26 Daniel Sieber,Max E Timm,Tobias Weller,Marie Suhling,Thomas Lenarz,Daniel Schurzig
HYPOTHESIS Assessment techniques for the cochlear spatial lateral wall are associated with inter-rater variability, but derived clinical recommendations nonetheless offer value for individualized electrode selection. BACKGROUND Anatomical variations influence the location of cochlear implant electrodes inside the cochlea. Preoperative planning allows individualization of the electrode based on characterization
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Metformin Reduces Tumor Growth in a Murine Flank Schwannoma Model. Otol. Neurotol. (IF 2.1) Pub Date : 2023-08-26 Sudhir Manickavel,Yolanda Hartman,Andrew Burns,Manuel A Lora Gonzalez,Jason Warram,Erika Walsh,Jacob B Hunter,Daniel E Killeen
HYPOTHESIS Metformin and aspirin reduce vestibular schwannoma (VS) growth. BACKGROUND There have been reported associations between patients with VS prescribed metformin and decreased tumor volumetric growth. Aspirin has also been associated with decreased VS growth in animal studies. METHODS Rat schwannoma cell lines were grown and implanted into 50 athymic nude mice. Tumors were grown to 5 mm, and
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Development and Chinese Cross-Cultural Adaptation of the Cochlear Implant Quality-of-Life Survey. Otol. Neurotol. (IF 2.1) Pub Date : 2023-08-23 Caleb J Fan,Maria A Mavrommatis,Vivian F Kaul,Theodore R McRackan,George B Wanna,Maura K Cosetti
OBJECTIVE To conduct the Chinese cross-cultural adaptation of the Cochlear Implant Quality of Life-10 Global (CIQOL-10 Global) instrument. PATIENTS Bilingual Chinese American cochlear implant users. INTERVENTION Chinese cross-cultural adaptation of the CIQOL-10 Global. MAIN OUTCOME MEASURE Description of the process of Chinese cross-cultural adaptation of the CIQOL-10 Global and pilot testing of the
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Incomplete Partition Type II Cochlear Malformations: Delineating the Three-Dimensional Structure from Digitized Human Histopathological Specimens. Otol. Neurotol. (IF 2.1) Pub Date : 2023-08-23 Chloe Swords,Alexander Geerardyn,MengYu Zhu,Jennifer T O'Malley,Peizhe Wu,Julie G Arenberg,Archana Podury,Cecilia Brassett,Manohar Bance,Alicia M Quesnel
HYPOTHESIS There are clinically relevant differences in scalae anatomy and spiral ganglion neuron (SGN) quantity between incomplete partition type II (IP-II) and normal cochleae. BACKGROUND IP-II is a commonly implanted cochlear malformation. Detailed knowledge of intracochlear three-dimensional (3D) morphology may assist with cochlear implant (CI) electrode selection/design and enable optimization
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Longitudinal Auditory Benefit for Elderly Patients After Cochlear Implant for Bilateral Hearing Loss, Including Those Meeting Expanded Centers for Medicare & Medicaid Services Criteria. Otol. Neurotol. (IF 2.1) Pub Date : 2023-08-23 Sarek Shen,Zahra Sayyid,Nicholas Andresen,Courtney Carver,Rachel Dunham,Dawn Marsiglia,Jennifer Yeagle,Charley C Della Santina,Steve Bowditch,Daniel Q Sun
OBJECTIVE To examine the effect of patient age on longitudinal speech understanding outcomes after cochlear implantation (CI) in bilateral hearing loss. STUDY DESIGN Retrospective cohort study. SETTING Tertiary academic center. PATIENTS One thousand one hundred five adult patients with bilateral hearing loss receiving a unilateral CI between 1987 and 2022InterventionsNone. MAIN OUTCOME MEASURES Postoperative
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Results of a Novel, Nonsurgical Bone-Conduction Hearing Aid for the Treatment of Conductive Hearing Loss in Australian Children. Otol. Neurotol. (IF 2.1) Pub Date : 2023-08-23 Roberta Marino,Katrise Eager,Jafri Kuthubutheen,Latif Kadhim,Dayse Távora-Vieira
OBJECTIVE To determine and compare the benefits a novel adhesive bone-conduction system and a conventional bone-conduction hearing aid (BCHA) on a softband for children with conductive hearing loss. STUDY DESIGN Prospective, single-subject randomized, crossover trial. SETTING Tertiary referral center in Australia. PARTICIPANTS Eight children aged from 4 to 17 years with conductive hearing loss. INTERVENTION
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Rates of Delayed Postcochlear Implant Pain in the Pediatric Population-Role of Proactive Approach. Otol. Neurotol. (IF 2.1) Pub Date : 2023-08-23 Tomer Rotlevi,Oren Ziv,Itai Hazan,Oded Cohen,Hasan Al Jaar,Mohamad Alkrenawi,Daniel M Kaplan
OBJECTIVE To investigate the rates of delayed postoperative cochlear implantation pain (DPCIP) in the pediatric population, using a "reach-out" proactive approach. Secondary aims included the possible impact of surgery extent or the patient ethnicity on DPCIP rates. MATERIALS AND METHODS A cross-sectional study was conducted at Soroka University Medical Center in Israel. Demographics and data regarding
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Cochlear Implant Upper Stimulation Levels: eSRT vs. Loudness Scaling. Otol. Neurotol. (IF 2.1) Pub Date : 2023-08-23 Jourdan T Holder,Melissa R Henry,Andrina E MacDonald,René H Gifford
OBJECTIVE To assess the difference in speech recognition and sound quality between programming upper stimulation levels using behavioral measures (loudness scaling) and electrically evoked stapedial reflex thresholds (eSRTs). STUDY DESIGN Double-blinded acute comparison study. SETTING Cochlear implant (CI) program at a tertiary medical center. PATIENTS Eighteen adult (mean age = 60 years) CI users
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Cognitive Performance, Sociodemographic Factors, Pure-Tone Audiometry, and their Association with Speech Discrimination: A Prospective Population-Based Study of 1,061 Older Adults. Otol. Neurotol. (IF 2.1) Pub Date : 2023-08-23 John P Marinelli,Nicholas S Reed,Christine M Lohse,Wanda L Fussell,Ronald C Petersen,Mary M Machulda,Maria Vassilaki,Matthew L Carlson
OBJECTIVE Hearing loss is increasingly recognized as a chronic disease state with important health sequelae. Although considered a central component of routine audiometric testing, the degree to which various patient factors influence speech discrimination is poorly characterized to date. The primary objective of the current work was to describe associations of cognitive performance, sociodemographic
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Incidence of Vestibular Schwannoma in Patients with Unilateral Tinnitus: A Systematic Review and Meta-Analysis. Otol. Neurotol. (IF 2.1) Pub Date : 2023-08-23 Azfar Javed,Magnus Okoh,Zahir Mughal,Faisal Javed,Keshav Gupta
OBJECTIVES Vestibular schwannoma (VS) is a tumor of the vestibulocochlear nerve. Current literature indicates that 1.6% of patients undergoing magnetic resonance imaging of the internal auditory meatus (MRI IAM) for audiovestibular symptoms are diagnosed with a VS. However, there is limited research reporting on patients who present with unilateral tinnitus without asymmetrical hearing loss. This study
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Investigating Socioeconomic Barriers to Cochlear Implantation. Otol. Neurotol. (IF 2.1) Pub Date : 2023-08-19 Rachel C Greiner,Jay T Rubinstein,Gavriel D Kohlberg
OBJECTIVE To explore socioeconomic disparities in cochlear implant evaluation (CIE) referrals and cochlear implantation. STUDY DESIGN Retrospective chart review. SETTING Tertiary referral academic center. METHODS Adult patients (n = 271) with an audiogram performed between 2015 and 2019 with a pure-tone average of at least 60 dB and word recognition score of 60% or less in the better-hearing ear or
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Key Genes and Endoscopic Radical Surgery in Primary Middle Ear Oncocytic Papillomas. Otol. Neurotol. (IF 2.1) Pub Date : 2023-08-19 Jihan Lyu,Wei Wang,Binjun Chen,Yanmei Wang,Haojie Sun,Yasheng Yuan,Dongdong Ren
OBJECTIVE Papillomas originating from the Schneiderian epithelium within the middle ear are extremely rare and may be associated with a high rate of recurrence and malignant transformation. Oncocytic papillomas represent the rarest pathological subtype of such tumors. The current investigation aimed to determine whether there exists a distinct mechanism underlying the incidence of oncocytic papillomas