-
Effects of Exercise Training and L-Arginine Loaded Chitosan Nanoparticles on Hippocampus Histopathology, β-Secretase Enzyme Function, APP, Tau, Iba1and APOE-4 mRNA in Aging Rats Neurotox. Res. (IF 3.7) Pub Date : 2024-03-05 Foad Feizolahi, Ehsan Arabzadeh, Amir Sarshin, Farshad Falahi, Zahra Dehghannayeri, Ali Ali Askari, Alexei Wong, Fariba Aghaei, Mehdi Zargani
-
Silica Nanoparticles Decrease Glutamate Uptake in Blood–Brain Barrier Components Neurotox. Res. (IF 3.7) Pub Date : 2024-03-04
Abstract Glutamate is the major excitatory amino acid in the vertebrate brain, playing an important role in most brain functions. It exerts its activity through plasma membrane receptors and transporters, expressed both in neurons and glia cells. Overstimulation of neuronal glutamate receptors is linked to cell death in a process known as excitotoxicity, that is prevented by the efficient removal of
-
Reference Gene Validation in the Embryonic and Postnatal Brain in the Rat Hyperhomocysteinemia Model Neurotox. Res. (IF 3.7) Pub Date : 2024-02-29 Anna A. Kovalenko, Alexander P. Schwarz, Anastasiia D. Shcherbitskaia, Anastasiia V. Mikhel, Dmitrii S. Vasilev, Alexander V. Arutjunyan
-
Interactions Between the Ubiquitin–Proteasome System, Nrf2, and the Cannabinoidome as Protective Strategies to Combat Neurodegeneration: Review on Experimental Evidence Neurotox. Res. (IF 3.7) Pub Date : 2024-02-23
Abstract Neurodegenerative disorders are chronic brain diseases that affect humans worldwide. Although many different factors are thought to be involved in the pathogenesis of these disorders, alterations in several key elements such as the ubiquitin–proteasome system (UPS), the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway, and the endocannabinoid system (ECS or endocannabinoidome)
-
E2F1 Mediates Traumatic Brain Injury and Regulates BDNF-AS to Promote the Progression of Alzheimer’s Disease Neurotox. Res. (IF 3.7) Pub Date : 2024-02-22 Yuting Ding, Wenkang Luan, Xuanlin Shen, Zhe Wang, Yongjun Cao
-
Molecular Docking Analysis at the Human α7-nAChR and Proliferative and Evoked-Calcium Changes in SH-SY5Y Cells by Imidacloprid and Acetamiprid Insecticides Neurotox. Res. (IF 3.7) Pub Date : 2024-02-20 Marcelo S. Guzman-Vallejos, Lenin J. Ramirez-Cando, Luis Aguayo, Santiago J. Ballaz
-
High Concentrations of Cannabidiol Induce Neurotoxicity in Neurosphere Culture System Neurotox. Res. (IF 3.7) Pub Date : 2024-02-13 Simone A. A. Romariz, Viviam Sanabria, Karina Ribeiro da Silva, Miguel L. Quintella, Bruna A. G. de Melo, Marimélia Porcionatto, Danilo Candido de Almeida, Beatriz M. Longo
-
METTL3 Mediates Microglial Activation and Blood–Brain Barrier Permeability in Cerebral Ischemic Stroke by Regulating NLRP3 Inflammasomes Through m6A Methylation Modification Neurotox. Res. (IF 3.7) Pub Date : 2024-02-13 Xue Cheng, Zhetan Ren, Huiyang Jia, Gang Wang
-
Diphenyl Diselenide Attenuates Mitochondrial Damage During Initial Hypoxia and Enhances Resistance to Recurrent Hypoxia Neurotox. Res. (IF 3.7) Pub Date : 2024-02-09 Guilherme S. Rieder, Marcos M. Braga, Ben Hur M. Mussulini, Emerson S. Silva, Gabriela Lazzarotto, Emerson André Casali, Diogo L. Oliveira, Jeferson L. Franco, Diogo O. G. Souza, João Batista T. Rocha
-
ZNF787 and HDAC1 Mediate Blood–Brain Barrier Permeability in an In Vitro Model of Alzheimer’s Disease Microenvironment Neurotox. Res. (IF 3.7) Pub Date : 2024-02-08 Lu Zhang, Baicheng Zhu, Xinxin Zhou, Hao Ning, Fengying Zhang, Bingju Yan, Jiajia Chen, Teng Ma
-
Exploring Caenorhabditis elegans as Parkinson’s Disease Model: Neurotoxins and Genetic Implications Neurotox. Res. (IF 3.7) Pub Date : 2024-02-06 Larissa Pereira Dantas da Silva, Erika da Cruz Guedes, Isabel Cristina Oliveira Fernandes, Lucas Aleixo Leal Pedroza, Gustavo José da Silva Pereira, Priscila Gubert
-
Cisplatin Provokes Peripheral Nociception and Neuronal Features of Therapy-Induced Senescence and Calcium Dysregulation in Rats Neurotox. Res. (IF 3.7) Pub Date : 2024-01-31 Tareq Saleh, Randa Naffa, Noor A. Barakat, Mohammad A. Ismail, Moureq R. Alotaibi, Mohammad Alsalem
-
Transposable Elements: Emerging Therapeutic Targets in Neurodegenerative Diseases Neurotox. Res. (IF 3.7) Pub Date : 2024-01-25 Shrishti Singh, Maheshkumar R. Borkar, Lokesh Kumar Bhatt
-
Monoclonal Antibody Targeting CGRP Relieves Cisplatin-Induced Neuropathic Pain by Attenuating Neuroinflammation Neurotox. Res. (IF 3.7) Pub Date : 2024-01-09 Shun Xie, Zhenfang Gao, Jiale Zhang, Cong Xing, Yanxin Dong, Lanyin Wang, Zhiding Wang, Yuxiang Li, Ge Li, Gencheng Han, Taiqian Gong
-
Divergent Pattern of Development in Rats and Humans Neurotox. Res. (IF 3.7) Pub Date : 2023-12-26 Wanda Campos Eusebi, Tomas Iorii, Antonella Presti, Rafael Grimson, Pablo Vázquez-Borsetti
-
Local Administrations of Iron Oxide Nanoparticles in the Prefrontal Cortex and Caudate Putamen of Rats Do Not Compromise Working Memory and Motor Activity Neurotox. Res. (IF 3.7) Pub Date : 2023-12-22 Ellen Irrsack, Sidar Aydin, Katja Bleckmann, Julia Schuller, Ralf Dringen, Michael Koch
-
Modulation of Neuronal Damage in DRG by Asprosin in a High-Glucose Environment and Its Impact on miRNA181-a Expression in Diabetic DRG Neurotox. Res. (IF 3.7) Pub Date : 2023-12-22 Muhammed Adam, Sibel Ozcan, Semih Dalkilic, Nalan Kaya Tektemur, Suat Tekin, Batuhan Bilgin, Munevver Gizem Hekim, Ferah Bulut, Muhammed Mirac Kelestemur, Sinan Canpolat, Mete Ozcan
-
Gut-Brain Axis Deregulation and Its Possible Contribution to Neurodegenerative Disorders Neurotox. Res. (IF 3.7) Pub Date : 2023-12-16 Francisca Villavicencio-Tejo, Margrethe A. Olesen, Laura Navarro, Nancy Calisto, Cristian Iribarren, Katherine García, Gino Corsini, Rodrigo A. Quintanilla
-
Static Magnetic Field Reduces Intracellular ROS Levels and Protects Cells Against Peroxide-Induced Damage: Suggested Roles for Catalase Neurotox. Res. (IF 3.7) Pub Date : 2023-12-14 Emilli Caroline Garcia Frachini, Jean Bezerra Silva, Barbara Fornaciari, Maurício S. Baptista, Henning Ulrich, Denise Freitas Siqueira Petri
-
Butyrate Protects and Synergizes with Nicotine against Iron- and Manganese-induced Toxicities in Cell Culture Neurotox. Res. (IF 3.7) Pub Date : 2023-12-14 Yousef Tizabi, Bruk Getachew, Michael Aschner
-
Mechanistic Implications of GSK and CREB Crosstalk in Ischemia Injury Neurotox. Res. (IF 3.7) Pub Date : 2023-12-13 Heena Khan, Annu Bangar, Amarjot Kaur Grewal, Thakur Gurjeet Singh
-
(m) RVD-hemopressin (α) Ameliorated Oxidative Stress, Apoptosis and Damage to the BDNF/TrkB/Akt Pathway Induced by Scopolamine in HT22 Cells Neurotox. Res. (IF 3.7) Pub Date : 2023-11-16 Ruisan Zhang, Xinliang He, Jianghong Cheng, Xiaofan Zhang, Chen Han, Yifan Liu, Peng Chen, Yang Wang
-
Metergoline Shares Properties with Atypical Antipsychotic Drugs Identified by Gene Expression Signature Screen Neurotox. Res. (IF 3.7) Pub Date : 2023-11-03 Chiara C Bortolasci, Emily J Jaehne, Damián Hernández, Briana Spolding, Timothy Connor, Bruna Panizzutti, Olivia M Dean, Tamsyn M Crowley, Alison R Yung, Laura Gray, Jee Hyun Kim, Maarten van den Buuse, Michael Berk, Ken Walder
-
Physical Exercise Promotes Beneficial Changes on Neurotrophic Factors in Mesolimbic Brain Areas After AMPH Relapse: Involvement of the Endogenous Opioid System Neurotox. Res. (IF 3.7) Pub Date : 2023-10-31 Rosa H.Z., Segat H.J., Barcelos R.C.S., Roversi Kr., Rossato D. R., Burger M.E.
-
Letter to the Neurotoxicity Research Community. Neurotox. Res. (IF 3.7) Pub Date : 2023-10-28 Gustavo C Ferreira
-
Biological Pathways Associated with Vitamins in Autism Spectrum Disorder Neurotox. Res. (IF 3.7) Pub Date : 2023-10-21 Darlan Gusso, Gustavo Ricardo Krupp Prauchner, Alessandra Schmitt Rieder, Angela T.S. Wyse
-
BIN1 in the Pursuit of Ousting the Alzheimer’s Reign: Impact on Amyloid and Tau Neuropathology Neurotox. Res. (IF 3.7) Pub Date : 2023-10-17 Ishnoor Kaur, Tapan Behl, G. Sundararajan, P. Panneerselvam, A. R. Vijayakumar, G. P. Senthilkumar, T. Venkatachalam, Dharmender Jaglan, Shivam Yadav, Khalid Anwer, Neeraj Kumar Fuloria, Aayush Sehgal, Monica Gulati, Sridevi Chigurupati
-
Pentoxifylline as Add-On Treatment to Donepezil in Copper Sulphate-Induced Alzheimer’s Disease-Like Neurodegeneration in Rats Neurotox. Res. (IF 3.7) Pub Date : 2023-10-12 Mohamed M. Elseweidy, Mohamed Mahrous, Sousou I. Ali, Mohamed A. Shaheen, Nahla N. Younis
-
Effect of Cannabidiol in LPS-Induced Toxicity in Astrocytes: Possible Role for Cannabinoid Type-1 Receptors Neurotox. Res. (IF 3.7) Pub Date : 2023-10-02 Hind Ibork, Sara El Idrissi, Simo Siyanda Zulu, Robert Miller, Lhoussain Hajji, Annabelle Manalo Morgan, Khalid Taghzouti, Oualid Abboussi
-
Correction to: The Effects of Long-term, Low-dose β-N-methylamino-L-alanine (BMAA) Exposures in Adult SODG93R Transgenic Zebrafish. Neurotox. Res. (IF 3.7) Pub Date : 2023-10-01 Ryan D Weeks,Sandra A Banack,Shaunacee Howell,Preethi Thunga,James S Metcalf,Adrian J Green,Paul A Cox,Antonio Planchart
-
RNA-Binding Proteins: A Role in Neurotoxicity? Neurotox. Res. (IF 3.7) Pub Date : 2023-09-30 Andrea Ocharán-Mercado, Jaqueline Loaeza-Loaeza, Yaneth Castro-Coronel, Leonor C. Acosta-Saavedra, Luisa C. Hernández-Kelly, Daniel Hernández-Sotelo, Arturo Ortega
-
Effects of Multiple High-Dose Methamphetamine Administration on Enteric Dopaminergic Neurons and Intestinal Motility in the Rat Model Neurotox. Res. (IF 3.7) Pub Date : 2023-09-27 Li He, Huihui Zheng, Jilong Qiu, Hong Chen, Huan Li, Yuejiao Ma, Yingying Wang, Qianjin Wang, Yuzhu Hao, Yueheng Liu, Qian Yang, Xin Wang, Manyun Li, Huixue Xu, Pu Peng, Zejun Li, Yanan Zhou, Qiuxia Wu, Shubao Chen, Xiaojie Zhang, Tieqiao Liu
-
Neuroprotective Potential of Tannic Acid Against Neurotoxic Outputs of Monosodium Glutamate in Rat Cerebral Cortex Neurotox. Res. (IF 3.7) Pub Date : 2023-09-15 Medine Sibel Karagac, Hamid Ceylan
-
Folic Acid and Folinic Acid Protect Hearts of Aging Triple-transgenic Alzheimer’s Disease mice via IGF1R/PI3K/AKT and SIRT1/AMPK Pathways Neurotox. Res. (IF 3.7) Pub Date : 2023-09-14 Da-Tong Ju, Rwei-Fen S. Huang, Bruce Chi-Kang Tsai, Yi-Chen Su, Ping-Ling Chiu, Yung-Ming Chang, V. Vijaya Padma, Tsung-Jung Ho, Chun-Hsu Yao, Wei-Wen Kuo, Chih-Yang Huang
-
Glial Activation, Mitochondrial Imbalance, and Akt/mTOR Signaling May Be Potential Mechanisms of Cognitive Impairment in Heart Failure Mice Neurotox. Res. (IF 3.7) Pub Date : 2023-09-05 Yanan Wu, Kaiyi Zhou, Baiyang Liu, Jindong Xu, Liming Lei, Jiaqi Hu, Xiao Cheng, Feng Zhong, Sheng Wang
-
Correction to: D‑Ribose‑L‑Cysteine Improves Glutathione Levels, Neuronal and Mitochondrial Ultrastructural Damage, Caspase‑3 and GFAP Expressions Following Manganese‑Induced Neurotoxicity Neurotox. Res. (IF 3.7) Pub Date : 2023-09-05 Grace T. Akingbade, Omamuyovwi M. Ijomone, Aminu Imam, Michael Aschner, Moyosore S. Ajao
-
Dexmedetomidine Promoted HSPB8 Expression via Inhibiting the lncRNA SNHG14/UPF1 Axis to Inhibit Apoptosis of Nerve Cells in AD Neurotox. Res. (IF 3.7) Pub Date : 2023-09-01 QingYun Tan, LiLi Liu, Shuo Wang, QingDong Wang, Yu Sun
-
Potential Key Proteins, Molecular Networks, and Pathways in Perinatal Hypoxia Neurotox. Res. (IF 3.7) Pub Date : 2023-08-31 Johann Gross, Mario Herrera-Marschitz
-
The Effects of Long-term, Low-dose β-N-methylamino-l-alanine (BMAA) Exposures in Adult SODG93R Transgenic Zebrafish Neurotox. Res. (IF 3.7) Pub Date : 2023-08-08 Ryan D. Weeks, Sandra A. Banack, Shaunacee Howell, Preethi Thunga, Adrian J. Green, Paul A. Cox, Antonio Planchart, James S. Metcalf
-
Correction to: Modulatory Role of Curcumin on Cobalt‑Induced Memory Deficit, Hippocampal Oxidative Damage, Astrocytosis, and Nrf2 Expression Neurotox. Res. (IF 3.7) Pub Date : 2023-08-03 Rademene S. Oria, Godson E. Anyanwu, Emmanuel A. Esom, Johnson N. Nto, Amechi U. Katchy, Augustine U. Agu, Omamuyovwi M. Ijomone
-
Effect of Quinolinic Acid on Behavior, Morphology, and Expression of Inflammatory/oxidative Status in Rats’ Striatum: Is Coenzyme Q10 a Good Protector? Neurotox. Res. (IF 3.7) Pub Date : 2023-07-29 Fernanda Silva Ferreira, Osmar Vieira Ramires Junior, Tiago Marcon dos Santos, Josiane Silva Silveira, Bruna Ferrary Deniz, Vinícius Santos Alves, Robson Coutinho-Silva, Luiz Eduardo Baggio Savio, Angela T. S. Wyse
-
Monoacylglycerol Lipase Inhibition Prevents Short-Term Mitochondrial Dysfunction and Oxidative Damage in Rat Brain Synaptosomal/Mitochondrial Fractions and Cortical Slices: Role of Cannabinoid Receptors Neurotox. Res. (IF 3.7) Pub Date : 2023-07-17 Karen Jaqueline Paredes-Ruiz, Karla Chavira-Ramos, Sonia Galvan-Arzate, Edgar Rangel-López, Çimen Karasu, Isaac Túnez, Anatoly V. Skalny, Tao Ke, Michael Aschner, Mario Orozco-Morales, Ana Laura Colín-González, Abel Santamaría
-
The Effects of Carvacrol on Transient Receptor Potential (TRP) Channels in an Animal Model of Parkinson’s Disease Neurotox. Res. (IF 3.7) Pub Date : 2023-07-15 Tülay Akan, Yasemin Aydın, Orhan Tansel Korkmaz, Emel Ulupınar, Faruk Saydam
-
Effect of Hesperidin on Sciatic Nerve Damage in STZ-Induced Diabetic Neuropathy: Modulation of TRPM2 Channel Neurotox. Res. (IF 3.7) Pub Date : 2023-07-13 Mehmet Hafit Bayir, Kenan Yıldızhan, Fikret Altındağ
-
Correction to: The Antiepileptic Drug Levetiracetam Protects Against Quinolinic Acid-Induced Toxicity in the Rat Striatum Neurotox. Res. (IF 3.7) Pub Date : 2023-07-08 Maricela Dircio-Bautista, Ana Laura Colín-González, Gabriela Aguilera, Marisol Maya-López, Juana Villeda Hernández, Sonia Galván-Arzate, Esperanza García, Isaac Túnez, Abel Santamaría
-
Bumetanide Attenuates Cognitive Deficits and Brain Damage in Rats Subjected to Hypoxia–Ischemia at Two Time Points of the Early Postnatal Period Neurotox. Res. (IF 3.7) Pub Date : 2023-06-28 Diorlon Nunes Machado, Luz Elena Durán-Carabali, Felipe Kawa Odorcyk, Andrey Vinicios Soares Carvalho, Ana Paula Rodrigues Martini, Livia Machado Schlemmer, Marcel de Medeiros de Mattos, Gabriel Pereira Bernd, Carla Dalmaz, Carlos Alexandre Netto
-
A Review on the Neurotoxic Effects of Doxorubicin Neurotox. Res. (IF 3.7) Pub Date : 2023-06-23 Katarzyna Kamińska, Agnieszka Cudnoch-Jędrzejewska
-
Exercise Improves Orofacial Pain and Modifies Neuropeptide Expression in a Rat Model of Parkinson’s Disease Neurotox. Res. (IF 3.7) Pub Date : 2023-06-02 Karina Henrique Binda, Marucia Chacur, Daniel Oliveira Martins
-
p-Nrf2/HO-1 Pathway Involved in Methamphetamine-induced Executive Dysfunction through Endoplasmic Reticulum Stress and Apoptosis in the Dorsal Striatum Neurotox. Res. (IF 3.7) Pub Date : 2023-05-18 Tao Wei, Jun-Da Li, Yu-Jing Wang, Wei Zhao, Fan Duan, Yan Wang, Ling-Ling Xia, Zhao-Bin Jiang, Xun Song, Yu-Qiong Zhu, Wen-Yi Shao, Ze Wang, Kang-Sheng Bi, Hui Li, Xiao-Chu Zhang, Dong-Liang Jiao
-
Mitochondrial Dysfunction as a Signaling Target for Therapeutic Intervention in Major Neurodegenerative Disease Neurotox. Res. (IF 3.7) Pub Date : 2023-05-10 Shubhada V. Mangrulkar, Nitu L. Wankhede, Mayur B. Kale, Aman B. Upaganlawar, Brijesh G. Taksande, Milind J. Umekar, Md. Khalid Anwer, Hamad Ghaleb Dailah, Syam Mohan, Tapan Behl
-
Human Placental Mesenchymal Stem Cell-derived Exosomes in Combination with Hyperbaric Oxygen Synergistically Promote Recovery after Spinal Cord Injury in Rats Neurotox. Res. (IF 3.7) Pub Date : 2023-05-08 Hosna Cheshmi, Hossein Mohammadi, Mitra Akbari, Davood Nasiry, Rafat Rezapour-Nasrabad, Mahdi Bagheri, Beheshteh Abouhamzeh, Mahnaz Poorhassan, Mehri Mirhoseini, Hossein Mokhtari, Esmaeil Akbari, Amir Raoofi
-
Posttreatment with Ospemifene Attenuates Hypoxia- and Ischemia-Induced Apoptosis in Primary Neuronal Cells via Selective Modulation of Estrogen Receptors Neurotox. Res. (IF 3.7) Pub Date : 2023-05-02 Bernadeta A. Pietrzak, Agnieszka Wnuk, Karolina Przepiórska, Andrzej Łach, Małgorzata Kajta
-
In Silico Interactions of Natural and Synthetic Compounds with Key Proteins Involved in Alzheimer’s Disease: Prospects for Designing New Therapeutics Compound Neurotox. Res. (IF 3.7) Pub Date : 2023-04-22 Mehran Ebrahimi Shah-abadi, Armin Ariaei, Fatemeh Moradi, Auob Rustamzadeh, Rastegar Rahmani Tanha, Nader Sadigh, Mohsen Marzban, Mahdi Heydari, Vahid Tavakolian Ferdousie
-
Connexin 43 Promotes Neurogenesis via Regulating Aquaporin-4 after Cerebral Ischemia Neurotox. Res. (IF 3.7) Pub Date : 2023-04-19 Heling Chu, Jing Dong, Yuping Tang, Chuyi Huang, Qihao Guo
-
NRF2 Antagonizes HIV-1 Tat and Methamphetamine-Induced BV2 Cell Ferroptosis by Regulating SLC7A11 Neurotox. Res. (IF 3.7) Pub Date : 2023-04-15 Shucheng Lin, Hao Cheng, Genmeng Yang, Chan Wang, Chi-Kwan Leung, Shuwei Zhang, Yi Tan, Huijie Zhang, Haowei Wang, Lin Miao, Yi Li, Yizhen Huang, Juan Li, Ruilin Zhang, Xiaofeng Zeng
-
Microglial Priming in Bilirubin-Induced Neurotoxicity Neurotox. Res. (IF 3.7) Pub Date : 2023-04-14 Hongmei Huang, Siyu Li, Yan Zhang, Chunmei He, Ziyu Hua
-
CNTN1 in the Nucleus Accumbens is Involved in Methamphetamine-Induced Conditioned Place Preference in Mice Neurotox. Res. (IF 3.7) Pub Date : 2023-04-04 Linxuan Zhang, Zehao Zeng, Xiaoyu Lu, Mengqing Li, Jiayu Yao, Guangjing Zou, Zhaorong Chen, Qian Li, Changqi Li, Fang Li
-
Correction to: Baicalin Attenuates Ketamine-Induced Neurotoxicity in the Developing Rats: Involvement of PI3K/Akt and CREB/BDNF/Bcl-2 Pathways Neurotox. Res. (IF 3.7) Pub Date : 2023-03-29 Daiying Zuo, Li Lin, Yumiao Liu, Chengna Wang, Jingwen Xu, Feng Sun, Lin Li, Zengqiang Li, Yingliang Wu
-
Blood–Brain Barrier Rescue by Roflumilast After Transient Global Cerebral Ischemia in Rats Neurotox. Res. (IF 3.7) Pub Date : 2023-03-16 Jéssica Mendes Bonato, Bianca Andretto de Mattos, Daniela Velasquez Oliveira, Humberto Milani, Jos Prickaerts, Rúbia Maria Weffort de Oliveira
-
Pharmacological Inhibition of p-21 Activated Kinase (PAK) Restores Impaired Neurite Outgrowth and Remodeling in a Cellular Model of Down Syndrome Neurotox. Res. (IF 3.7) Pub Date : 2023-03-03 Natalia Barraza-Núñez, Ramón Pérez-Núñez, Belén Gaete-Ramírez, Alejandra Barrios-Garrido, Christian Arriagada, Karen Poksay, Varghese John, Jean-Vianney Barnier, Ana María Cárdenas, Pablo Caviedes