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  • Mechanical thrombectomy for ischaemic stroke in the anterior circulation: off-hours effect
    J. Neurol. (IF 4.204) Pub Date : 2020-05-28
    Olfa Kaaouana, Nicolas Bricout, Barbara Casolla, François Caparros, Lucie Della Schiava, François Mounier-Vehier, Marco Pasi, Nelly Dequatre-Ponchelle, Jean-Pierre Pruvo, Charlotte Cordonnier, Hilde Hénon, Didier Leys

    Background Patients treated at off-hours for acute conditions have increased mortality rates. This effect has been poorly evaluated in patients treated by mechanical thrombectomy (MT). Objective This study aimed at comparing outcomes between patients treated at off-hours and at working hours by MT for acute stroke due to large-vessel occlusion in the anterior circulation, in a well-organised network

    更新日期:2020-05-28
  • BOLD signal within and around white matter lesions distinguishes multiple sclerosis and non-specific white matter disease: a three-dimensional approach
    J. Neurol. (IF 4.204) Pub Date : 2020-05-28
    Dinesh K. Sivakolundu, Kathryn L. West, Mark D. Zuppichini, Andrew Wilson, Tatum M. Moog, Aiden P. Blinn, Braeden D. Newton, Yeqi Wang, Thomas Stanley, Xiaohu Guo, Bart Rypma, Darin T. Okuda

    Multiple sclerosis (MS) diagnostic criteria are based upon clinical presentation and presence of white matter hyperintensities on two-dimensional magnetic resonance imaging (MRI) views. Such criteria, however, are prone to false-positive interpretations due to the presence of similar MRI findings in non-specific white matter disease (NSWMD) states such as migraine and microvascular disease. The coexistence

    更新日期:2020-05-28
  • An update on idiopathic intracranial hypertension in adults: a look at pathophysiology, diagnostic approach and management
    J. Neurol. (IF 4.204) Pub Date : 2020-05-27
    Simona Toscano, Salvatore Lo Fermo, Ester Reggio, Clara Grazia Chisari, Francesco Patti, Mario Zappia

    Idiopathic intracranial hypertension is a neurological syndrome determined by a rise in intracranial pressure without a detectable cause. Course and prognosis may be changeable, requiring a multidisciplinary approach for its diagnosis and management. Although its precise pathogenesis is still unknown, many studies have been carried out to define the possible causal and associated factors, such as retinoids

    更新日期:2020-05-27
  • Different EEG brain activity in right and left handers during visually induced self-motion perception
    J. Neurol. (IF 4.204) Pub Date : 2020-05-27
    Michaela McAssey, James Dowsett, Valerie Kirsch, Thomas Brandt, Marianne Dieterich

    Visually induced self-motion perception (vection) relies on visual–vestibular interaction. Imaging studies using vestibular stimulation have revealed a vestibular thalamo-cortical dominance in the right hemisphere in right handers and the left hemisphere in left handers. We investigated if the behavioural characteristics and neural correlates of vection differ between healthy left and right-handed

    更新日期:2020-05-27
  • Key gait findings for diagnosing three syndromic categories of dynamic instability in patients with balance disorders
    J. Neurol. (IF 4.204) Pub Date : 2020-05-27
    Roman Schniepp, Ken Möhwald, Max Wuehr

    With the emergence of affordable, clinical-orientated gait analysis techniques, clinicians may benefit from a general understanding of quantitative gait analysis procedures and their clinical applications. This article provides an overview of the potential of a quantitative gait analysis for decision support in three clinically relevant scenarios of early stage gait disorders: scenario I: gait ataxia

    更新日期:2020-05-27
  • Sural nerve biopsy: current role and comparison with serum neurofilament light chain levels
    J. Neurol. (IF 4.204) Pub Date : 2020-05-27
    Sara Mariotto, Sara Carta, Silvia Bozzetti, Cecilia Zivelonghi, Daniela Alberti, Serena Zanzoni, Massimiliano Filosto, Simone Fusina, Salvatore Monaco, Francesca Castellani, Alessandro Mantovani, Tiziana Cavallaro, Chiara Briani, Sergio Ferrari

    The diagnosis of peripheral neuropathies can be challenging with consequent difficulties in patients’ management. The aim of this study was to explore the current diagnostic role of sural nerve biopsy and to compare pathological findings with serum neurofilament light chain levels (NfL) as biomarkers of axonal damage. We collected demographic, clinical, and paraclinical data of patients referred over

    更新日期:2020-05-27
  • Risk of acute brain lesions in dizzy patients presenting to the emergency room: who needs imaging and who does not?
    J. Neurol. (IF 4.204) Pub Date : 2020-05-27
    Björn Machner, Jin Hee Choi, Peter Trillenberg, Wolfgang Heide, Christoph Helmchen

    The usefulness of brain imaging studies in dizzy patients presenting to the emergency department (ED) is controversial. We aimed to assess the ‘real-world’ probability of ischemic stroke and other acute brain lesions (ABLs) in these patients to create an algorithm that helps decision-making on whether which and when brain imaging is needed. By reviewing medical records, we identified 610 patients presenting

    更新日期:2020-05-27
  • Neurological manifestations of COVID-19: a review of what we know so far
    J. Neurol. (IF 4.204) Pub Date : 2020-05-26
    Panagiotis Gklinos

    Coronavirus disease 2019 (COVID‐19) has become a pandemic disease globally. While it mostly presents with respiratory symptoms, it has already been found that it could manifest with a series of neurological symptoms as well, either at presentation or during the course of the disease. Symptoms vary from non-specific such as headache or dizziness to more specific such as convulsions and cerebrovascular

    更新日期:2020-05-26
  • A parsimonious score with a free web tool for predicting disability after an ischemic stroke: the Parsifal Score
    J. Neurol. (IF 4.204) Pub Date : 2020-05-26
    E. Muiño, A. Bustamante, A. Rodriguez-Campello, C. Gallego-Fabrega, A. Ois, C. Carrera, N. Cullell, N. Torres-Aguila, J. Cárcel-Márquez, M. Rubiera, C. A. Molina, E. Cuadrado-Godia, E. Giralt-Steinhauer, J. Jiménez-Conde, J. Montaner, I. Fernández-Cadenas, J. Roquer

    Background Most of the models to predict prognosis after an ischemic stroke include complex mathematical equations or too many variables, making them difficult to use in the daily clinic. We want to predict disability 3 months after an ischemic stroke in an independent patient not receiving recanalization treatment within the first 24 h, using a minimum set of variables and an easy tool to facilitate

    更新日期:2020-05-26