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Traumatic Head Injuries from Ceiling Fans at a Pediatric Level I Trauma Center in the United States. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-11-18 Logan Muzyka,Holly Hughes Garza,Diala Merheb,Julie Sanchez,Elizabeth Tyler-Kabara,Karla A Lawson
Background/ Objective Several studies describe traumatic head injuries caused by ceiling fans in Australia, the Middle East, and Malaysia. Some injuries required neurosurgical intervention, especially those caused by metallic ceiling fans. This study describes traumatic head injuries caused by ceiling fans at a single Pediatric Level 1 Trauma Center in the southern United States. Methods Medical records
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Effectiveness and safety of epilepsy surgery for pediatric patients with intractable epilepsy: A clinical retrospective study from a single-center experience. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-11-03 Müge Dolgun,Duygu Dölen,Emek Uyur Yalçın,İlyas Dolaş,Tuğrul Cem Ünal,Nermin Görkem Şirin,Ayfer Sakarya Güneş,Nerses Bebek,Aydın Aydoseli,Candan Gürses,Bülent Kara,Altay Sencer
INTRODUCTION Pediatric epilepsy surgery is an effective treatment modality for patients with drug-resistant epilepsy (DRE). Early pediatric surgery yields favorable results for DRE in terms of seizure control and neurophysiological outcome. In this study, pediatric patients were categorized based on their age (above 3 years old and below 3 years old) to demonstrate the effectiveness and safety of surgical
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Middle Meningeal Artery Embolization in Pediatric Patients. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-10-30 Sima Vazquez,David A Zuckerman,Chirag Gandhi,Fawaz Al-Mufti,Carrie Muh,Justin Santarelli,Jared M Pisapia
BACKGROUND Middle meningeal artery (MMA) embolization has been increasingly applied in adult populations for the treatment of chronic subdural hematomas (cSDH). There is a paucity of literature on the indications, safety, and outcomes of MMA embolization in the pediatric population. SUMMARY A systematic literature review on pediatric patients undergoing MMA embolization was performed. We also report
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Treatment course and outcomes of intracranial teratomas in pediatric patients: a retrospective 15-year case series study. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-10-25 Adela Wu,Michael C Jin,Hannes Vogel,Susan Hiniker,Cynthia Campen,Laura M Prolo,Gerald A Grant
Introduction There is no standard treatment paradigm for intracranial teratomas, a rare subset of primary intracranial nongerminomatous germ cell tumors (NGGCT), which comprise less than 1% of pediatric brain tumors. This case series retrospectively analyzes treatment and outcomes of pediatric intracranial teratomas from a single institution. Methods Authors reviewed a comprehensive pathology database
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Subtemporal Decompression in Resistant Slit Ventricle Syndrome in Children: An Observational Study and Survival Analysis. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-10-17 Mehdi Khan,Claudia Louise Craven,Muhammad Zubair Tahir
Introduction Slit ventricle syndrome (SVS) remains a challenging problem in the early shunted pediatric population. Various surgical and non-surgical treatments have been devised for this condition. However, there currently is no gold standard for its optimal management. Among various treatment modalities, sub-temporal decompression (STD) is often performed as a last resort. We present our experience
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Contemporary Knowledge Update of Pediatric Neuro-Oncology Management: An Overview for Neurosurgeons. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-09-27 Nir Shimony,Lissa Baird,Moise Danielpour,George I Jallo
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The predictors of seizures in patients with Encephalocele; an 11-year experience from a tertiary hospital. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-09-26 Amirhosein Nejat,Samuel Berchi Kankam,Vahid Heidari,Keyvan Tayebi Meybodi,Zohreh Habibi,Sajedeh Karami,Farideh Nejat
INTRODUCTION To investigate and identify the predictors associated with the incidence of seizures in patients with encephalocele (EC). METHOD A retrospective analysis was undertaken of patients treated for EC at a tertiary medical center in Tehran between 2010 and 2021. Data including age at presentation, gender, location, size and contents of EC, ventriculomegaly, hydrocephalus, associated anomalies
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A New Measure of Posterior Morphology in Sagittal Craniosynostosis: The Occipital Bullet Index. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-09-13 Griffin P Bins,Deborah Cull,Ryan G Layton,Samuel Kogan,Larry Zhou,Blake Dunson,Lisa R David,Christopher M Runyan
BACKGROUND Sagittal craniosynostosis (SC) is associated with scaphocephaly, an elongated narrow head shape. Assessment of regional severity in the scaphocephalic head is limited by the use of serial CT imaging or complex computer programing. Three-dimensional measurements of cranial surface morphology provide a radiation-free alternative for assessing cranial shape. This study describes the creation
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Radiotherapy for Primary Pediatric Central Nervous System Malignancies: Current Treatment Paradigms and Future Directions. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-09-13 Kevin X Liu,Daphne A Haas-Kogan,Hesham Elhalawani
BACKGROUND Central nervous system tumors are the most common solid tumors in childhood. Treatment paradigms for pediatric central nervous system malignancies depend on elements including tumor histology, age of patient, and stage of disease. Radiotherapy is an important modality of treatment for many pediatric central nervous system malignancies. SUMMARY While radiation contributes to excellent overall
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Serial Neuroendoscopic Lavage for the Treatment of Elevated Cerebrospinal Fluid Protein Levels in Infants with Gram-negative Rod Ventriculitis. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-09-13 Jasmine L Hect,Roberta K Sefcik,Kamil W Nowicki,Joel Katz,Stephanie Greene
INTRODUCTION Gram-negative rod (GNR) bacterial ventriculitis is a rare complication of shunt-dependent hydrocephalus, often requiring an extended and invasive treatment course. Accumulation of purulent material, as well as empyema and septation formation, limits circulation of antibiotics and infection clearance. Supplementation of standard care with neuroendoscopic-guided intraventricular lavage with
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Comparison between MRI and the combination of 2D and 3D US in the prenatal diagnosis of closed spina bifida. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-09-12 Weiping Zhang,Jingling Wang,Hui Wu,Li Chen
INTRODUCTION Closed spina bifida (CSB) is a rare condition with a challenging prenatal diagnosis. Herein, we assess the conventional two-dimensional (2D) ultrasound (US) combined with three-dimensional (3D) ultrasound (US) and MRI in the prenatal diagnosis of CSB. METHODS In this retrospective study, we included 20 cases of fetal CSB confirmed by postnatal MRI, post-mortem pathological examination
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Advances in Imaging Modalities for Pediatric Brain and Spinal Cord Tumors. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-08-21 Thierry A G M Huisman,Rajan Patel,Stephen Kralik,Nilesh K Desai,Avner Meoded,Karen Chen,Howard L Weiner,Daniel J Curry,Maarten Lequin,Mariette Kranendonk,Gunes Orman,George Jallo
BACKGROUND Neuroimaging has evolved from anatomical imaging toward a multi-modality comprehensive anatomical and functional imaging in the past decades, important functional data like perfusion-weighted imaging, permeability imaging, diffusion-weighted imaging (DWI), and diffusion tensor imaging (DTI), tractography, metabolic imaging, connectomics, event-related functional imaging, resting state functional
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A Molecular Update and Review of Current Trials in Paediatric Low-Grade Gliomas. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-08-21 Sarah Al-Jilaihawi,Stephen Lowis
BACKGROUND Paediatric low-grade gliomas (pLGGs) are the most common primary brain tumour in children. Though considered benign, slow-growing lesions with excellent overall survival, their long-term morbidity can be significant, both from the tumour and secondary to treatment. Vast progress has been made in recent years to better understand the molecular biology underlying pLGGs, with promising implications
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Knowledge Review of Spinal Deformity and the Need for Fusion and Fixation following Treatment for Spinal Tumors among the Pediatric Age Group. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-08-02 Jay I Kumar,George I Jallo,Nir Shimony
BACKGROUND Spinal tumors are rare pathology in the pediatric population. The tumors can be classified as extradural, intradural extramedullary, or intramedullary. Any of the spinal tumors can eventually lead to spinal deformity. The progressive spinal deformity can be part of the initial presentation or evolve on long follow-up, even years after the initial intervention and treatment. SUMMARY Management
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Intracranial Empyemas in the COVID-19 Era: A New Phenomenon? A Paediatric Case Series and Review of the Literature. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-06-30 Benjamin J Hall,John C Duddy,Katerina Apostolopoulou,Raenette David,Arthur Kurzbuch,Abhishek Nadkarni,Sandhya Trichinopoly Krishna,Ben Cooper,Hayley Gouldbourne,Dawn Hennigan,William Dawes,Jonathan Ellenbogen,Christopher Parks,Benedetta Pettorini,Ajay Sinha,Conor Mallucci
INTRODUCTION We present the largest series of paediatric intracranial empyemas occurring after COVID-19 infection to date, and discuss the potential implications of the pandemic on this neurosurgical pathology. METHODS Patients admitted to our centre between January 2016 and December 2021 with a confirmed radiological diagnosis of intracranial empyema were retrospectively reviewed, excluding non-otorhinological
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Letter to the Editor regarding "Behavioral Improvements following Lesion Resection for Pediatric Epilepsy: Pediatric Psychosurgery?" Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-06-30 Fardad T Afshari,Muhammad Zubair Tahir
Not Applicable (Letter to the editor).
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White and Gray Matter Perfusion in Children with Moyamoya Angiopathy after Revascularization Surgery. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-06-28 Elena Filimonova,Azniv Martirosyan,Konstantin Ovsiannikov,Anton Pashkov,Jamil Rzaev
INTRODUCTION Surgical revascularization is very effective in patients with moyamoya angiopathy (MMA) and leads to improvements in cortical perfusion parameters. However, changes in white matter hemodynamics are still underestimated. To date, only a few studies have examined brain perfusion changes within deep white matter after bypass surgery in patients with MMA. METHODS Ten children with MMA were
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Pediatric Primary Intracranial Malignant Melanoma: Case Report and Literature Review. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-06-14 Mervyn J R Lim,Enrica E K Tan,Ru Xin Wong,Kenneth T E Chang,Marielle V Fortier,Tien Meng Cheong,Lee Ping Ng,Sharon Y Y Low
INTRODUCTION Primary intracranial malignant melanoma (PIMM) is an extremely rare primary brain tumor with most cases diagnosed in adults. To date, there are only a few cases reported in the pediatric population. Owing to its infrequency, there are no established guidelines to treat this aggressive neoplasm. Recent insights suggest that PIMM are molecularly different between adults and children, whereby
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Influence of Paraspinal Growth-Friendly Spinal Implants in Children with Spinal Muscular Atrophy on Parasol Deformity, Rib-Vertebral Angles, Thoracic, and Lung Volumes. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-06-14 Julia Austein,Friederike Austein,Katja A Lüders,Lena Braunschweig,Konstantinos Tsaknakis,Heiko M Lorenz,Anna K Hell
INTRODUCTION Children with spinal muscular atrophy (SMA) and progressive neuromuscular scoliosis often require early growth-friendly spinal implant (GFSI) treatment for deformity correction with implant fixation either through pedicle screws or bilateral to the spine using ribto pelvis fixation. It has been proposed that the latter fixation may change the collapsing parasol deformity via changes in
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Lipoblastomatosis Extended into the Lumbar Spinal Canal in a Child: A Case Report. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-06-14 Marina Saga,Akira Yamaura,Tadashi Miyagawa
INTRODUCTION Lipoblastoma and lipoblastomatosis are rare benign mesenchymal adipose tumors that originate from embryonic white adipocytes and occur most commonly in infancy and early childhood. Lipoblastomas occur in the extremities and trunk, including the retroperitoneum and peritoneal cavity. Therefore, infiltration into the spinal canal has rarely been reported. CASE PRESENTATION A 4-year-old girl
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Current Open Trials and Molecular Update for Pediatric Embryonal Tumors. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-05-26 Tom Rosenberg,Tabitha Cooney
BACKGROUND Embryonal tumors are highly malignant cancers of the central nervous system, with a relatively high incidence in infants and young children. Even with intensive multimodal treatment, the prognosis of many types is guarded, and treatment-related toxicity is significant. Recent advances in molecular diagnostics allowed the discovery of novel entities and inter-tumor subgroups, with opportunities
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A Comparison of Clinical Outcomes for Subependymal Giant Cell Astrocytomas Treated with Laser Interstitial Thermal Therapy, Open Surgical Resection, and mTOR Inhibitors. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-05-24 Scott Boop,David Bonda,Stephanie Randle,Sarah Leary,Nicholas Vitanza,Erin Crotty,Edward Novotny,Seth Friedman,Richard G Ellenbogen,Sharon Durfy,Hannah Goldstein,Jeffrey G Ojemann,Jason S Hauptman
INTRODUCTION Subependymal giant cell astrocytoma (SEGA) is the most common CNS tumor in patients with tuberous sclerosis complex (TSC). Although these are benign, their proximity to the foramen of Monroe frequently causes obstructive hydrocephalus, a potentially fatal complication. Open surgical resection has been the mainstay of treatment; however, this can cause significant morbidity. The development
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Extraskeletal Myxoid Chondrosarcoma of the Jugular Foramen in a Pediatric Patient: A Case Report and Comprehensive Review of the Literature. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-05-18 Kadir Oktay,Araz Aliyev,Halil Emre Alcan,Seyda Erdogan,Kerem Mazhar Ozsoy,Nuri Eralp Cetinalp,Tahsin Erman
INTRODUCTION Extraskeletal myxoid chondrosarcoma of the jugular foramen is a rare clinical entity, especially in the pediatric population. Thus, it can be confused with other pathologies. CASE PRESENTATION We report an extremely rare case of a 14-year-old female patient with jugular foramen myxoid chondrosarcoma that was completely removed through microsurgical resection. CONCLUSION The primary purpose
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Use of a Prophylactic Retrograde-Flushing Device in High-Risk Pediatric Patients with Ventriculoperitoneal Shunts: A Technical Note. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-05-05 Michael Vinzani,Mohammed Alshareef,Ramin Eskandari
INTRODUCTION Ventriculoperitoneal shunt (VPS) malfunction rates are as high as 40% in the first year with posthemorrhagic hydrocephalus (PHH) patients having the highest proximal occlusion risk. Debris, protein, and cellular ingrowth most commonly obstruct the proximal ventricular catheter and/or valve. Historically, no preventative methods have demonstrated efficacy. We present a technical note and
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Diagnostic Accuracy of Ocular Ultrasonography in Identifying Raised Intracranial Pressure among Pediatric Population. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-05-05 Vignan Kappagantu,Tej Prakash Sinha,Deepak Agrawal,Nayer Jamshed,Akshay Kumar,Atin Kumar,R M Pandey,Bharath Gopinath,Vidhya Bhushan,Atul Kumar Tiwari,Sanjeev Kumar Bhoi
INTRODUCTION Role of CT scan, MRI, ophthalmoscopy, direct monitoring by a transducer probe in identifying raised intracranial pressure (ICP) in emergency department is limited. There are few studies correlating elevated optic nerve sheath diameter (ONSD) measured by point of care ultrasound (POCUS) with raised ICP in pediatrics emergencies. We studied the diagnostic accuracy of ONSD, crescent sign
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Midline-Sparing Interapophysealaminar Decompression Technique for Management of Lumbar Stenosis in Pediatric Achondroplasia. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-05-02 Stacey Podkovik,Kevin N Martins,Hammad Ghanchi,Brian W Hanak
INTRODUCTION Achondroplasia is the most common form of short-limb dwarfism in humans, with an incidence of 1 in 25,000-40,000 live births. About one-third of achondroplasia patients will require operative intervention for lumbar spinal stenosis, generally presenting with progressive neurogenic claudication. The anatomy of the achondroplastic lumbar spine, with shortened pedicles, hypertrophic zygapophyseal
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Recent Advancements in Ependymoma: Challenges and Therapeutic Opportunities. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-05-02 Kelsey C Bertrand,Paul Klimo
BACKGROUND Ependymoma is one of the most common malignant pediatric brain tumors and can be difficult to treat. Over the last decade, much progress has been made in the understanding of the underlying molecular drivers within this group of tumors, but clinical outcomes remain unchanged. SUMMARY Here, we review the most recent molecular advances in pediatric ependymoma, evaluate results of recent clinical
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Patient and Caregiver Reported Outcome Measures after Single-Level Selective Dorsal Rhizotomy in Pediatric and Young Adult Patients with Spastic Cerebral Palsy Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-04-19 Abeelan Rasadurai, Nicole Alexandra Frank, Ladina Aurea Greuter, Maria Licci, Peter Weber, Stephanie Jünemann, Raphael Guzman, Jehuda Soleman
Introduction: The aim of this cohort study is to assess the outcome of single-level selective dorsal rhizotomy (SDR) in children and young adults with spastic cerebral palsy (CP) treated at our institution, focusing on patient-reported outcome measures (PROMs) and quality of life (QoL) of patients and their caregivers. Methods: We included consecutive patients undergoing SDR from 2018 to 2020 at our
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Double lumbar localization of Myelomeningocele: Case report Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-04-19 Nadjib Belfatmi, Ahmed S Motawei, Ayoub Rezkallah, Nour Djihane Benarous, Adnan Hassan Ahmed, Sherief Ghozy, Mohamed A. Zaazoue, Mohamed Si Saber
Introduction: myelomeningocele (MMC) is a malformation resulting from the neural tube’s failure to close during embryonic development, the majority of the cases of neural tube defects (NTDs) were prevalent as single location lesions along the spine, however multiple neural tube defects (MNTDs) are a very rare condition. Only a few cases of MNTDs were found in the literature. Case Report: we report
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Giant supratentorial brain tumors in children: functional outcome and progression-free survival analysis. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-04-10 Amparo Saenz, yamila basilotta marquez, Emma A Dalton, Romina Argañaraz, Beatriz Mantese
Introduction: This study aimed to identify factors affecting progression-free survival (PFS) in pediatric patients with giant supratentorial brain tumors (GSBT) treated with surgical excision. The secondary aim was to analyze how these same factors affected the functional outcome in the long term. Methods: We performed a retrospective, analytical, single-center cohort study. We included all pediatric
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Carotid artery aneurysm and hypomelanosis of Ito Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-04-03 Zeferino Demartini Jr., Bernardo Corrêa de Almeida Teixeira, Gelson Luis Koppe
Introduction: Hypomelanosis of Ito is a rare neurocutaneous syndrome characterized by hypopigmented skin lesions, abnormalities of the central nervous system, skeletal system, eyes and teeth. Case Presentation: We present a case of a 4-year-old boy with hypomelanosis of Ito and neck pulsatile mass due to a giant left common carotid dissecting aneurysm. Discussion: To our knowledge, this is the first
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Chronic Pleural Effusion in Ventriculoperitoneal Shunt due to Diaphragmatic CSF Fistula. Report of a case treated by Endoscopic Choroid Plexus Coagulation and literature review Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-04-01 Simon Schmid, Andrea Bevot, Felix Neunhoeffer, Jörg Michel, Matthias Kumpf, Matthias Reimold, Michael Hofbeck, Martin Schuhmann
Chronic pleural cerebrospinal fluid (CSF) effusion is a rare complication after ventriculoperitoneal (VP) shunt insertion and only 18 cases in children and adults have been described so far without catheter dislocation to the intrathoracic cavity. We report on a 4-year-old girl with a complex history of underlying neurogenetic disorder, a hypoxic ischemic encephalopathy after influenza A Infection
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Primary Human Herpes Virus-6 causing recalcitrant pyrexia after pilocytic astrocytoma resection Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-03-25
Introduction: Human Herpes Virus-6 (HHV-6) is a ubiquitous virus but can lead to deleterious clinical manifestations due to its predilection for the pediatric central nervous system. Despite significant literature describing its common clinical course, it is rarely considered as a causative agent in CSF pleocytosis in the setting of craniotomy and external ventricular drainage device. Identification
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Approaches to Incidental Intradural Tumors of the Spine in the Pediatric Population Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-03-22 Andrew M. Hersh, Daniel Lubelski, Nicholas Theodore, Daniel M. Sciubba, George Jallo, Nir Shimony
Background: Incidental intradural tumors of the spine in the pediatric population are rare lesions whose management remains unclear. Surgeons must balance the risks of iatrogenic deficits and complications after surgical resection against the risks from progressive growth of the tumor. Moreover, the natural history of an incidental finding can be difficult to predict. Here we review the literature
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International/Resident Traveling Notice 2023 Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-03-15 Moise Danielpour, Timothy M. George, David Frim, Ken R. Winston, David G. McLone, J. Gordon McComb, Donald H. Reigel, David M. Frim, Jogi V. Pattisapu, Nathan R. Selden, Spyros Sgouros, Dianna M.E. Bardo, Anthony M. Avellino, Michael H. Kohrman, Mark Krieger, Rodolfo Hakim, Deepak Kumar Gupta, Martin U. Schuhmann, Marcus Stoodley, George Jallo, Hassan I. El-Shafei, Yasuo Aihara, Shlomo Constantini
Pediatr Neurosurg
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Use of the Posterior Auricular Artery for Indirect Bypass in Moyamoya: A Pediatric Case Series Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-02-21 J Chris Hawkins, Megan V Ryan, Sarah Graber, Ilana Neuberger, Jodi Slade, Michael Young, John A. Maloney, C Corbett Wilkinson
Introduction: Encephaloduroarteriosynangiosis (EDAS) for moyamoya is predominantly performed using a branch of the superficial temporal artery (STA) as the donor artery. At times, other branches of the external carotid artery (ECA) are better suited for EDAS than is the STA. There is little information in the literature concerning using the posterior auricular artery (PAA) for EDAS in the pediatric
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Post Covid-19 MIS-C Related Cerebral Infarction in a Pediatric Patient Managed with Decompressive Craniectomy Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-02-15
Most people who are infected with the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) are asymptomatic or present with mild upper respiratory symptoms. This is especially true in the pediatric population; however, rarely, a massive cytokine storm can develop causing multisystem inflammatory syndrome associated with COVID (MIS-C). Furthermore, children may also suffer from acute ischemic
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Post-COVID-19 Multisystem Inflammatory Syndrome-Related Cerebral Infarction in a Pediatric Patient Managed with Decompressive Craniectomy. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-02-15 Ryan D Morgan,Reagan A Collins,Laszlo Nagy
INTRODUCTION Most people who are infected with the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) are asymptomatic or present with mild upper respiratory symptoms. This is especially true in the pediatric population; however, rarely, a massive cytokine storm can develop, causing multisystem inflammatory syndrome associated with COVID (MIS-C). Furthermore, children may also suffer
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Behavioral Improvements Following Lesion Resection for Pediatric Epilepsy: Pediatric Psychosurgery? Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-02-14 Huy Dang, Abdul Basit Khan, Nisha Gadgil, Himanshu Sharma, Cristina Trandafir, Fatema Malbari, Howard L Weiner
Introduction: Resection of brain lesions associated with refractory epilepsy to achieve seizure control is well-accepted. However, concurrent behavioral effects of these lesions such as changes in mood, personality, and cognition and the effects of surgery on behavior have not been well characterized. We describe 5 such children with epileptogenic lesions and significant behavioral abnormalities which
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Delayed migration of Onyx embolic agent after preoperative embolization of an arteriovenous malformation in a pediatric patient: A case report and review of the literature Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-02-13 Bailey R. Nussbaum, Patrick Graupman, Collin M. Torok, Tiffany A. Yesavage, Eric S. Nussbaum
Introduction: Brain arteriovenous malformations (AVMs) are increasingly being treated with Onyx liquid embolic agent (Onyx, Medtronic, Inc.). The phenomenon of delayed Onyx migration is not well documented in the literature. Moreover, the clinical presentation associated with Onyx migration is not well understood. Case Presentation: A pediatric patient with a history of neonatal seizures was referred
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Acknowledgement to Reviewers Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-02-10
Pediatr Neurosurg 2022;57:447–448
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Endoscopic third ventriculostomy with choroid plexus cauterization in treating infantile hydrocephalus: an experience from Mali. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-02-08 Oumar Diallo, Mahamadou Dama, Landry Konan, Oumar Coulibaly, Daouda Sissoko, Abdoulaye Hima Maiga
ABSTRACT Introduction Pediatric Hydrocephalus is a common disease in sub-Saharan Africa. In Mali, 350-400 new cases are diagnosed in our center yearly. With a total land mass of 1.241.000 km2, patients in remote areas must travel up to 1500km to access neurosurgical care. Hence, treatment and follow-ups of “shunted” patients are difficult. In this context, endoscopic third ventriculostomy with choroid
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Updates in the Management of Central and Peripheral Nervous System Tumors among Patients with Neurofibromatosis Type 1 and Neurofibromatosis Type 2 Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-02-06
Background: Neurofibromatosis type 1 and neurofibromatosis type 2 are unrelated, distinct genetic disorders characterized by the development of central and peripheral nervous system tumors. Summary: Neurofibromatosis type 1 is the most common inherited tumor predisposition syndrome with a lifelong increased risk of benign and malignant tumor development, such as glioma and nerve sheath tumors. Neurofibromatosis
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Practical Algorithm for the management of multisutural craniosynostosis with associated Chiari malformation and/or hydrocephalus Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-01-31 Gelsomina Aruta, Pietro Fiaschi, Marco Ceraudo, Gianluca Piatelli, Valeria Capra, Andrea Bianconi, Andrea Rossi, Francesca Secci, Marco Pavanello
The association between multisutural craniosynostosis with Chiari malformation (CM), venous hypertension and hydrocephalus is widely described in the literature, especially in children with pediatric craniofacial syndromes. Some efforts have been done in the last years to understand the complex pathogenetic mechanisms underlying this association and several theories have been proposed. However, whatever
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Advances and Clinical Trials Update in the Treatment of Diffuse Intrinsic Pontine Gliomas Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-01-13 Cecilia Dalle Ore, Christina Coleman-Abadi, Nalin Gupta, Sabine Mueller
Diffuse intrinsic pontine gliomas (DIPG) are high grade glioma (HGG) that occur primarily in children, and represent a leading cause of death in pediatric patients with brain tumors with a median overall survival of only 8-11 months. While these lesions were previously thought to behave similarly to adult HGG, emerging data have demonstrated that DIPG are a biologically distinct entity from adult HGG
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Peri-Insular hemispherotomy: A systematic review and institutional experience Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-01-13 Charles F Yates, Stephen Malone, Kate Riney, Ubaid Shah, Martin J Wood
Purpose: Peri-insular hemispherotomy (PIH) is a hemispheric separation technique under the broader hemispherotomy group, a surgical treatment for patients with intractable epilepsy. Hemispherotomy techniques such as the PIH, vertical parasagittal hemispherotomy (VPH), and modified-lateral hemispherotomy are commonly assessed together, despite significant differences in anatomical approach and patient
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Comparison of Follow-Up Length-Matched Single-Center Myelomeningocele Postnatal Closure Cohort to the Management of Myelomeningocele Study (MOMS) Trial Results Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-01-10 Stephanie Greene, Jasmine L. Hect, Kristin Weaver, Michael M. McDowell
NA
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Review of the Recent Changes in the WHO Classification for Pediatric Brain and Spinal Cord Tumors Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-01-06
Background: Periodic updates to the World Health Organization (WHO) classification system for central nervous system (CNS) tumors reflect advances in the pathological diagnosis, categorization, and molecular underpinnings of primary brain, spinal cord, and peripheral nerve tumors. The 5th edition of the WHO Classification of CNS Tumors was published in 2021. This review discusses the guiding principles
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Review of Pediatric Extraosseous Chordomas With A Unique, Illustrative Case Pediatr. Neurosurg. (IF 0.7) Pub Date : 2023-01-02 Benjamin J Lee, Audrey Grossen, Helen Shi, Sara Abu Mehsen, Zhongxin Yu, Kar-Ming A Fung, Khairuddin Memon, Joanna E. Gernsback
Introduction: Chordoma is a rare, aggressive tumor that is believed to originate from notochord remnants. It can occur anywhere from the clivus to the sacrum and often recurs even after resection and radiotherapy. We present a unique case that initially suggested a different pathology based on imaging and presentation but was found to be a chordoma on gross and pathological analysis. Case Presentation:
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Immunotherapy for Pediatric Brain and Spine Tumors, Current State and Future Directions. Pediatr. Neurosurg. (IF 0.7) Pub Date : 2022-12-22 Dagoberto Estevez-Ordonez, Sam Gary, Travis J. Atchley, Pedram Maleknia, Jordan George, Nicholas M.B. Laskay, Evan Gross, Rishi Devulapalli, James M. Johnston
Background Brain tumors are the most common solid tumors and the leading cause of cancer-related deaths in children. Incidence in the US has been on the rise for the last 2 decades. While therapeutic advances in diagnosis and treatment have improved survival and quality of life in many children, prognosis remains poor and current treatments have significant long-term sequelae. Summary There is a substantial
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Sex Differences in Comorbidities of Pediatric Craniosynostosis at Presentation Pediatr. Neurosurg. (IF 0.7) Pub Date : 2022-12-21 Peyton Presto, Reagan A Collins, John Garza, Omar Fadi Zeitouni, Laszlo Nagy
Introduction: Craniosynostosis is a common pediatric presentation in which the premature fusion of one or more cranial sutures results in a misshapen skull. This birth defect is often associated with comorbidities due to structural impacts on nearby anatomical features. While there is some evidence for a male-predominance among craniosynostosis patients, little has been investigated regarding sex differences
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Considerations for choice of cranioplasty material for pediatric patients Pediatr. Neurosurg. (IF 0.7) Pub Date : 2022-12-07
Introduction: Optimal material and timing of cranioplasty in the pediatric population continues to be debated. Autologous and alloplastic materials have various indications for use and risk factors for complications. Methods: A single-center retrospective cohort study was undertaken of all pediatric patients who underwent cranioplasty with any material from 1991-2021. Results: 149 cranioplasty implants
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Considerations for choice of cranioplasty material for pediatric patients Pediatr. Neurosurg. (IF 0.7) Pub Date : 2022-12-07
Introduction: Optimal material and timing of cranioplasty in the pediatric population continues to be debated. Autologous and alloplastic materials have various indications for use and risk factors for complications. Methods: A single-center retrospective cohort study was undertaken of all pediatric patients who underwent cranioplasty with any material from 1991-2021. Results: 149 cranioplasty implants
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Occult Intraosseous Dermoid Cyst at the Nasofrontal Junction Pediatr. Neurosurg. (IF 0.7) Pub Date : 2022-11-30 Yusuke S. Hori, John S Albanese, John G Meara, Mark R. Proctor
Introduction: An extension of the dermoid cyst below the nasal bone has been identified in 10% of patients in a large series of nasal dermoid cysts, but these are generally easily identifiable and connected to the tract. To date, no previous reports have documented a case with intraosseous dermoid cyst which was completely hidden in the nasal bone. Case Presentation: An 8 year-old previously healthy
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Occult Intraosseous Dermoid Cyst at the Nasofrontal Junction Pediatr. Neurosurg. (IF 0.7) Pub Date : 2022-11-30
Introduction: An extension of the dermoid cyst below the nasal bone has been identified in 10% of patients in a large series of nasal dermoid cysts, but these are generally easily identifiable and connected to the tract. To date, no previous reports have documented a case with intraosseous dermoid cyst which was completely hidden in the nasal bone. Case Presentation: An 8 year-old previously healthy
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Left ophthalmic segment internal carotid artery aneurysm treated with flow diversion in a child with Apert syndrome: technical note Pediatr. Neurosurg. (IF 0.7) Pub Date : 2022-10-28 Jaims Lim, Justin M. Cappuzzo, Muhammad Waqas, Faisal Almayman, Jeffrey A. Fearon, Elad I. Levy
Introduction: Prevalence of intracranial aneurysms in children with Apert syndrome has not been described, and development of an aneurysm as a complication secondary to craniofacial surgery has never been reported. Case Presentation: We report the rare case of a 10-year-old boy with Apert syndrome who underwent craniofacial reconstruction surgery consisting of subcranial Le Fort III osteotomies, bilateral
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Left Ophthalmic Segment Internal Carotid Artery Aneurysm Treated with Flow Diversion in a Child with Apert Syndrome: Technical Note Pediatr. Neurosurg. (IF 0.7) Pub Date : 2022-10-28
Introduction: Prevalence of intracranial aneurysms in children with Apert syndrome has not been described, and development of an aneurysm as a complication secondary to craniofacial surgery has never been reported. Case Presentation: We report the rare case of a 10-year-old boy with Apert syndrome who underwent craniofacial reconstruction surgery consisting of subcranial Le Fort III osteotomies, bilateral
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Detection and Management of Tethered Cord in Anorectal Malformation: A Survey of Pediatric Neurosurgeons in the United States Pediatr. Neurosurg. (IF 0.7) Pub Date : 2022-10-18 Caitlin A. Smith, Lauren N. Nicassio, Samuel E. Rice-Townsend, Jeffrey R. Avansino, Jason S. Hauptman
Introduction: The reported prevalence of tethered spinal cord in patients with anorectal malformations (ARM) ranges from 9% to 64%. Practice patterns surrounding the diagnosis and management of tethered cord are suspected to vary, with consideration to type of spine imaging, adjunct imaging modalities, what patients are offered surgical intervention, and how patients are followed after detethering
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Detection and Management of Tethered Cord in Anorectal Malformation: A Survey of Pediatric Neurosurgeons in the United States Pediatr. Neurosurg. (IF 0.7) Pub Date : 2022-10-18
Introduction: The reported prevalence of tethered spinal cord in patients with anorectal malformations (ARMs) ranges from 9% to 64%. Practice patterns surrounding the diagnosis and management of tethered cord (TC) are suspected to vary, with consideration to the type of spine imaging, adjunct imaging modalities, what patients are offered surgical intervention, and how patients are followed after detethering