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Association of level of adherence to Mediterranean diet with cognitive and dementia status in subjects with chronic diseases: a cross-sectional study Nutr. Neurosci. (IF 3.6) Pub Date : 2024-03-14 Abeer Al Hatab, Kishore Ganana Sam, Semira Abdi Beshir, Asim Ahmed Elnour, Nadia Al Mazrouei, Khalid Awad Al-Kubaisi, Maisoun Alkaabi, Abdulla Al Amoodi, Vineetha Menon, Abuelnor Mohammed, Sami Fatehi Abdalla
Background: The Mediterranean diet has been linked to brain neuroprotection. Evidence from meta-analyses showed reduced risk of dementia with greater intake of vegetables and fruits, fish, and the ...
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Altered reward processing following sucrose bingeing in male and female mice Nutr. Neurosci. (IF 3.6) Pub Date : 2024-03-15 Gaëlle Awad, Anne-Sophie Aubry, Mary C. Olmstead, Katia Befort
Objectives: Binge eating disorder (BED) is the most prevalent eating disorder associated with multiple adverse health effects, especially mental health issues, including substance use disorders and...
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Natural compounds for oxidative stress and neuroprotection in schizophrenia: composition, mechanisms, and therapeutic potential Nutr. Neurosci. (IF 3.6) Pub Date : 2024-03-11 Anam N. Khan, Rahul D. Jawarkar, Magdi E.A. Zaki, Aamal A. Al Mutairi
An imbalance between the generation of reactive oxygen species (ROS) and the body's antioxidant defense mechanisms is believed to be a critical factor in the development of schizophrenia (SCZ) like...
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Examining the association of breakfast skipping with sleep disturbance, mental health, and health-related quality of life: data from the 2018 Korean community health survey Nutr. Neurosci. (IF 3.6) Pub Date : 2024-03-11 Sung Min Jung, Mee-Ri Lee
Objectives: This study aimed to explore the relationship between breakfast skipping and its effects on sleep disorders, mental health, and health-related quality of life among Korean adults.Methods...
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Calorie restriction protects against acute systemic LPS-induced inflammation Nutr. Neurosci. (IF 3.6) Pub Date : 2024-02-22 Vanessa-Fernanda da Silva, Vitor Gayger-Dias, Rafaela Sampaio da Silva, Thomas Michel Sobottka, Anderson Cigerce, Lílian Juliana Lissner, Krista Minéia Wartchow, Letícia Rodrigues, Caroline Zanotto, Fernanda Carolina Telles da Silva Fróes, Marina Seady, André Quincozes-Santos, Carlos-Alberto Gonçalves
Caloric restriction (CR) has been proposed as a nutritional strategy to combat chronic diseases, including neurodegenerative diseases, as well as to delay aging. However, despite the benefits of CR...
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Nutrition is associated with differences in multisensory integration in healthy older adults Nutr. Neurosci. (IF 3.6) Pub Date : 2024-02-22 Alan O’Dowd, Deirdre M.A. O’Connor, Rebecca J. Hirst, Annalisa Setti, Rose Anne Kenny, Fiona N. Newell
Diet can influence cognitive functioning in older adults and is a modifiable risk factor for cognitive decline. However, it is unknown if an association exists between diet and lower-level processe...
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Maternal usage of varying levels of dietary folate affects the postnatal development of cerebellar folia and cortical layer volumes Nutr. Neurosci. (IF 3.6) Pub Date : 2024-02-17 Philip Maseghe Mwachaka, Peter Gichangi, Adel Abdelmalek, Paul Odula, Julius Ogeng’o
The cerebellum has a long, protracted developmental period; therefore, it is more sensitive to intrauterine and postnatal insults like nutritional deficiencies. Folate is an essential nutrient in f...
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Adjunctive silymarin supplementation and its effects on disease severity, oxidative stress, and inflammation in patients with Alzheimer’s disease Nutr. Neurosci. (IF 3.6) Pub Date : 2024-02-14 Seyed Mohammad Navabi, Daniel Elieh-Ali-Komi, Daryoush Afshari, Farjam Goudarzi, Ehsan Mohammadi-Noori, Kiana Heydari, Fatemeh Heydarpour, Amir Kiani
Brain tissue in Alzheimer's patients is exposed to oxidative stress. Silymarin is an adjunct drug that has anti-inflammatory and antioxidant properties.This study aimed to evaluate the effect of si...
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Causal association between plant foods intake and Alzheimer's disease: a Mendelian randomization study Nutr. Neurosci. (IF 3.6) Pub Date : 2024-02-12 Xinmin Deng, Jingyi Zhu, Jingtao Liang, Wen Chang, Xiaofeng Lv, Rui Lai
Alzheimer's disease (AD) is a degenerative disease of the nervous system. Observational studies have found an association between plant food intake and AD. However, it is unclear whether this assoc...
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Sex- and age-dependent associations of EPA and DHA with very short sleep duration in adults: a cross-sectional analysis Nutr. Neurosci. (IF 3.6) Pub Date : 2024-02-09 Qianning Liu, Qingsong Shan, Zahid Ur Rehman
This study aimed to compare the efficacy of dietary intake of eicosapentaenoic acid (EPA; 20:5 ω-3) and docosahexaenoic acid (DHA; 22:6 ω-3) on very short sleep duration (<5 h/night) in adults.The ...
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Glucose intolerance induces anxiety-like behaviors independent of obesity and insulin resistance in a novel model of nutritional metabolic stress Nutr. Neurosci. (IF 3.6) Pub Date : 2024-02-06 Mohammed Al-Onaizi, Kawthar Braysh, Selma S. Alkafeef, Dana Altarrah, Shorouk Dannoon, Dalal Alasousi, Hawraa Adel, Mariam Al-Ajmi, Anwar Kandari, Rawan Najem, Rasheeba Nizam, Michayla R. Williams, Sumi John, Thangavel Alphonse Thanaraj, Rasheed Ahmad, Heba Al-Hussaini, Fahd Al-Mulla, Fawaz Alzaid
Objectives: Type 2 diabetes (T2D) is a metabolic disease of major public health concern. It impacts peripheral tissues and the central nervous system, leading to systemic dysmetabolism and neurocog...
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Is there a link between the inflammatory potential of a diet and mental health among patients with migraine? Findings from a cross-sectional survey Nutr. Neurosci. (IF 3.6) Pub Date : 2024-02-06 Fatemeh Sadat Navab, Amir Hadi, Ibtesam Jahlan, Gholamreza Askari, Fariborz Khorvash, Arman Arab
In this study, we aimed to evaluate the relationship between the dietary inflammatory index (DII) and mental health outcomes among patients with migraine headaches.In this cross-sectional study, 26...
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Brain energetics and glucose transport in metabolic diseases: role in neurodegeneration Nutr. Neurosci. (IF 3.6) Pub Date : 2024-01-31 Orquídea G. Méndez-Flores, Luisa C. Hernández-Kelly, Tatiana N. Olivares-Bañuelos, Gabriel López-Ramírez, Arturo Ortega
Neurons and glial cells are the main functional and structural elements of the brain, and the former depends on the latter for their nutritional, functional and structural organization, as well as ...
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Potential of dietary polyphenols for protection from age-related decline and neurodegeneration: a role for gut microbiota? Nutr. Neurosci. (IF 3.6) Pub Date : 2024-01-29 F. C. Ross, D. E. Mayer, J. Horn, J. F. Cryan, D. Del Rio, E. Randolph, C. I. R. Gill, A. Gupta, R. P. Ross, C. Stanton, E. A. Mayer
Many epidemiological studies have shown the beneficial effects of a largely plant-based diet, and the strong association between the consumption of a Mediterranean-type diet with healthy aging incl...
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Assessing the pattern electroretinogram as a proxy measure for dopamine in the context of iron deficiency Nutr. Neurosci. (IF 3.6) Pub Date : 2024-01-25 Sarah F. Newbolds, Michael J. Wenger
Animal studies have suggested that dietary iron deficiency (ID) negatively affects dopamine (DA) synthesis and re-uptake, which in turn negatively affects memory and cognition. This study was inten...
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Low-carbohydrate diet as a nutritional intervention in a major depression disorder: focus on relapse prevention Nutr. Neurosci. (IF 3.6) Pub Date : 2024-01-21 Michał Walaszek, Zofia Kachlik, Wiesław Jerzy Cubała
Objectives: Mood disorders are trending to be among the leading causes of years lived with disability. Despite multiple treatment options, around 30% patients with major depressive disorder (MDD) d...
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An extract of Hibiscus sabdariffa improves short-term memory in rats with experimental diabetic hyperglycemia Nutr. Neurosci. (IF 3.6) Pub Date : 2024-01-09 Silvia J. López-Pérez, Mónica E. Ureña-Guerrero, Jacinto Bañuelos-Pineda
Calyxes of Hibiscus sabdariffa (Hs) contain anthocyanins, that normalize blood glucose levels (BGL) in diabetic patients. Diabetes also causes memory alterations, which could hypothetically decreas...
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Refined diet consumption increases neuroinflammatory signalling through bile acid dysmetabolism Nutr. Neurosci. (IF 3.6) Pub Date : 2024-01-03 Emily Connell, Britt Blokker, Lee Kellingray, Gwénaëlle Le Gall, Mark Philo, Matthew G. Pontifex, Arjan Narbad, Michael Müller, David Vauzour
Over recent decades, dietary patterns have changed significantly due to the increasing availability of convenient, ultra-processed refined foods. Refined foods are commonly depleted of key bioactiv...
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Nutritional strategies modulating the gut microbiome as a preventative and therapeutic approach in normal and pathological age-related cognitive decline: a systematic review of preclinical and clinical findings Nutr. Neurosci. (IF 3.6) Pub Date : 2024-01-02 Rieke Sproten, Donatus Nohr, Daria Guseva
The proportion of the elderly population is on the rise across the globe, and with it the prevalence of age-related neurodegenerative diseases. The gut microbiota, whose composition is highly regul...
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The impact of flavonoids and BDNF on neurogenic process in various physiological/pathological conditions including ischemic insults: a narrative review Nutr. Neurosci. (IF 3.6) Pub Date : 2023-12-27 Esen Yılmaz, Saltuk Bugra Baltaci, Rasim Mogulkoc, Abdulkerim Kasım Baltaci
Ischemic stroke is the leading cause of mortality and disability worldwide with more than half of survivors living with serious neurological sequelae thus, it has recently attracted considerable at...
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Does hazelnut consumption affect brain health and function against neurodegenerative diseases? Nutr. Neurosci. (IF 3.6) Pub Date : 2023-12-27 Shadi Talebi, Fariba Khodagholi, Zahra Bahaeddin, Mitra Ansari Dezfouli, Arman Zeinaddini-Meymand, Samuel Berchi Kankam, Forough Foolad, Fatemeh Alijaniha, Fatemeh Fayazi Piranghar
Introduction: A healthy daily diet and consuming certain nutrients, such as polyphenols, vitamins, and unsaturated fatty acids, may help neuronal health maintenance. Polyphenolic chemicals, which h...
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Effects of riboflavin in the treatment of brain damage caused by oxygen deprivation: an integrative systematic review Nutr. Neurosci. (IF 3.6) Pub Date : 2023-12-14 Eulália Rebeca da Silva-Araújo, Raul Manhães-de-Castro, Paula Brielle Pontes, Diego Bulcão Visco, Diego Cabral Lacerda, Henrique José Cavalcanti Bezerra Gouveia, Ana Elisa Toscano
Brain oxygen deprivation causes morphological damage involved in the formation of serious pathological conditions such as stroke and cerebral palsy. Therapeutic methods for post-hypoxia/anoxia inju...
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Effect of perinatal dietary protein deficiency on some neurochemicals and cytoarchitectural balance, in F1 and F2 generations of rats Nutr. Neurosci. (IF 3.6) Pub Date : 2023-11-23 Nosarieme Omoregie Abey, Osaretin Albert Taiwo Ebuehi, Ngozi Awa Imaga
Protein deficiency, characterized by an inadequate intake of protein in the diet that fails to meet the body’s physiological requirements across various stages, can lead to detrimental outcomes. Th...
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High use of non-hydrogenated plant source oils and mayonnaise sauce increase the risk of Parkinson disease Nutr. Neurosci. (IF 3.6) Pub Date : 2023-11-23 Sorayya Kheirouri, Mohammad Alizadeh, Majid Keramati
Objectives: This study aimed to assess the contribution of edible/cooking oils and mayonnaise sauce in the severity, motor and non-motor symptoms, and risk of Parkinson's disease (PD).Methods: In t...
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Mediterranean diet-based intervention to improve depressive symptoms: analysis of the PREDIDEP randomized trial Nutr. Neurosci. (IF 3.6) Pub Date : 2023-11-22 Beatriz M. Cabrera-Suárez, Jose L. Hernández-Fleta, Patricio Molero, Ana González-Pinto, Francisca Lahortiga, Claudio Cabrera, Carlos Chiclana-Actis, Almudena Sánchez-Villegas, PREDI-DEP investigators
The effect of an intervention based on Mediterranean diet on reducing recurrence risk or subsyndromal depressive symptoms in recovered depressed patients has not been explored.The PREDIDEP study wa...
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Energy-adjusted dietary inflammatory index and cognitive function in Chinese older adults: a population-based cross-sectional study Nutr. Neurosci. (IF 3.6) Pub Date : 2023-11-22 Lili Chen, Jinxiu Liu, Xiuli Li, Zhaoyi Hou, Yongbao Wei, Mingfeng Chen, Bixia Wang, Huizhen Cao, Rongyan Qiu, Yuping Zhang, Xinli Ji, Ping Zhang, Mianxiang Xue, Linlin Qiu, Linlin Wang, Hong Li
Diet can regulate systemic inflammation, which may play an important role in the development and progression of cognitive impairment and dementia. To explore the relationship between the dietary in...
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Associations between short-chain fatty acid levels and mood disorder symptoms: a systematic review Nutr. Neurosci. (IF 3.6) Pub Date : 2023-11-17 Caroline Fussing Bruun, Tue Haldor Hansen, Maj Vinberg, Lars Vedel Kessing, Klara Coello
Background: Available evidence points to a possible role of Short Chain Fatty Acids (SCFAs) in mood disorders. This is the first systematic review to map the associations between SCFA levels and mo...
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A systematic review and meta-analysis of chondroitinase ABC promotes functional recovery in rat models of spinal cord injury Nutr. Neurosci. (IF 3.6) Pub Date : 2023-11-11 Ya-yun Zhang, Rui-rui Xue, Min Yao, Zhuo-yao Li, Cai-wei Hu, Yu-xiang Dai, Yi-de Fang, Xing Ding, Jin-hai Xu, Xue-jun Cui, Wen Mo
To comprehensively assess the neurologic recovery potential of chondroitinase ABC (ChABC) in rats after spinal cord injury (SCI).The PubMed, Embase, ScienceDirect, Web of Science, and China Nationa...
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Association between vitamin D, depression, and sleep health in the National Health and Nutrition Examination Surveys: a mediation analysis Nutr. Neurosci. (IF 3.6) Pub Date : 2023-11-14 Jingliang Shuai, Mengqi Gao, Qi Zou, Youming He
This study aimed to assess the association between vitamin D and sleep health and to investigate whether depression could mediate this relationship.A cross-sectional analysis was performed using th...
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Supplementation with Manihot esculenta Crantz (Cassava) leaves’ extract prevents recognition memory deficits and hippocampal antioxidant dysfunction induced by Amyloid-β Nutr. Neurosci. (IF 3.6) Pub Date : 2023-11-10 Guilherme Salgado Carrazoni, Nathália Billig Garces, Caroline Ramires Cadore, Priscila Marques Sosa, Roberta Cattaneo, Pâmela Billig Mello-Carpes
Objective: The Manihot esculenta Crantz (Cassava) is a typical South American plant rich in nutrients and energetic compounds. Lately, our group has shown that non-pharmacological interventions wit...
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Symptomatic idiopathic intracranial hypertension triggered by Ramadan intermittent fasting: a case report Nutr. Neurosci. (IF 3.6) Pub Date : 2023-11-10 Ryan Nelson, S. L. Silliman, K. Zarroli
Idiopathic intracranial hypertension (IIH) is a disorder that primarily affects obese women of reproductive age. The exact pathogenesis of IIH is unknown though multiple etiologies have been propos...
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Pyrus pashia fruit extract and its major phytometabolite chrysin prevent hippocampal apoptosis and memory impairment in PTZ-kindled mice Nutr. Neurosci. (IF 3.6) Pub Date : 2023-11-06 Priyanka Sharma, Amita Kumari, Padmanabh Singh, Sweta Srivas, Mahendra K. Thakur, Siva Hemalatha
Epilepsy is a chronic neurological condition with recurrent seizures. One-third of epilepsy patients experience unacceptable side effects from antiepileptic drugs. Pyrus pashia is a deciduous tree ...
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Fruits and vegetables intake may be associated with a reduced odds of multiple sclerosis: a systematic review and dose–response meta-analysis of observational studies Nutr. Neurosci. (IF 3.6) Pub Date : 2023-10-18 Danial Fotros, Morvarid Noormohammadi, Soodeh Razeghi Jahromi, Mohammadjavad Abdolkarimi
Multiple sclerosis (MS) is an immune-mediated condition of the central nervous system (CNS). Intake of fruits and vegetables high in vitamins, minerals, fiber, and active molecules contributes to t...
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The effect of a low-calorie, high-protein diet on psychometric variables in obese individuals: a Randomized Clinical Trial Nutr. Neurosci. (IF 3.6) Pub Date : 2023-10-19 Fatemeh Sadat Hashemi Javaheri, Alireza Ostadrahimi, Mohsen Nematy, Seyyed Mostafa Arabi, Kazem Rahmani, Mahnaz Amini
The last decade has seen the increased prevalence of obesity as a public health challenge, particularly in low- and middle-income countries. At the same time, studies have shown that there is a two...
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Trehalose consumption ameliorates pathogenesis in an inducible mouse model of the Fragile X-associated tremor/ataxia syndrome Nutr. Neurosci. (IF 3.6) Pub Date : 2023-09-30 Emre Kul, Oliver Stork
Trehalose is a naturally occurring sugar found in various food and pharmaceutical preparations with the ability to enhance cellular proteostasis and reduce the formation of toxic intracellular prot...
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The neuroprotective effect of vitamin D in Parkinson's disease: association or causation Nutr. Neurosci. (IF 3.6) Pub Date : 2023-09-20 Amin A. Hafiz
Parkinson's disease (PD) is a chronic neurodegenerative disease (NDD) due to the degeneration of dopaminergic neurons (DNs) in the substantia nigra (SN). PD is characterized by diverse motor sympto...
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Daily fat intake is associated with basolateral amygdala response to high-calorie food cues and appetite for high-calorie food Nutr. Neurosci. (IF 3.6) Pub Date : 2023-09-20 Yuko Nakamura, Shinsuke Koike
Animal studies have indicated that fat intake mediates amygdala activation, which in turn promotes fat intake, while amygdala activation increases the preference for fat and leads to increased fat ...
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Dietary quality and the gut microbiome in early-stage Parkinson’s disease patients Nutr. Neurosci. (IF 3.6) Pub Date : 2023-09-14 Hyun Jeong Yoon, Woorim Kang, Sungyang Jo, Yun Su Hwang, Je Hee Lee, Sun Ju Chung, Yoo Kyoung Park
ABSTRACT Background The prevalence of Parkinson’s disease (PD) has increased steadily with the increase of the elderly population. PD may influence dietary intake and quality, and the gut microbiome composition. The present study examined differences in dietary intake and quality between PD patients and controls according to sex. In addition, we assessed the gut microbiome composition. Methods This
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Antidepressant-like effects of tomatidine and tomatine, steroidal alkaloids from unripe tomatoes, via activation of mTORC1 in the medial prefrontal cortex in lipopolysaccharide-induced depression model mice Nutr. Neurosci. (IF 3.6) Pub Date : 2023-09-13 Satoshi Deyama, Rinako Sugie, Masaki Tabata, Katsuyuki Kaneda
ABSTRACT Ketamine, an N-methyl-D-aspartate receptor antagonist, produces rapid antidepressant effects in patients with treatment-resistant depression. However, owing to the undesirable adverse effects of ketamine, there is an urgent need for developing safer and more effective prophylactic and therapeutic interventions for depression. Preclinical studies have demonstrated that activation of the mechanistic
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A comprehensive and systematic review of the potential neuroprotective effect of quercetin in rat models of spinal cord injury Nutr. Neurosci. (IF 3.6) Pub Date : 2023-09-10 Ke Zhu, Zhong Zheng, Ya-yun Zhang, Zhuo-yao Li, Ai-fang Zhou, Cai-wei Hu, Bing Shu, Long-yun Zhou, Qi Shi, Yong-jun Wang, Min Yao, Xue-jun Cui
ABSTRACT Context Spinal cord injury (SCI) is a potentially fatal neurological disease with severe complications and a high disability rate. An increasing number of animal experimental studies support the therapeutic effect of quercetin, which is a natural anti-inflammatory and antioxidant bioflavonoid. Objective This paper reviewed the therapeutic effect of quercetin on a rat SCI model and summarized
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Glutamine stimulates the S6K/4E-BP branch of insulin signalling pathway to mitigate human poly(Q) disorders in Drosophila disease models Nutr. Neurosci. (IF 3.6) Pub Date : 2023-09-02 Shweta Tandon, Surajit Sarkar
ABSTRACT Human polyglutamine [poly(Q)] disorders such as Huntington's disease, different types of ataxias, etc. are devastating brain illnesses which are characterised by the presence of neurotoxic protein aggregates in the affected neurons. We have recently reported that S6K/4E-BP mediated growth promoting branch of insulin signalling pathway alleviates human poly(Q) induced neurotoxicity in Drosophila
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Ameliorating effect of Citrus trifoliata L. fruits extract on motor incoordination, neurodegeneration and oxidative stress in Parkinson’s disease model Nutr. Neurosci. (IF 3.6) Pub Date : 2023-09-02 Mostafa A. Abdel-Kawy, Basma Emad Aboulhoda, Camilia G. Michel, Mohamed S. Sedeek, Farid N. Kirollos, Marwa A. Masoud
ABSTRACT Background Citrus trifoliate fruit (also known as Trifoliate orange) is one of the commercially-cultivated Citrus genus of plants belonging to the Rutaceae family. It has been traditionally-utilized in treatment of neurodegenerative disorders. However, the scientific evidence verifying this utilization needs further elucidation. Aim of the study Characterization of the bioactive constituents
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Neonatal overnutritional programming impairs the hypophagia and neuron activation induced by acute lipopolysaccharide in adult male rats Nutr. Neurosci. (IF 3.6) Pub Date : 2023-08-31 Ana Luiza Wunderlich, Larissa Stopa, Andressa Busetti Martins, Camila Franciele de Souza, Érica Monteiro, Danielly Aguiar, Rhauany Guergolette, Polyana Shishido, Cassia Thais Zaia, Ernane Uchoa
ABSTRACT Nutritional status during critical windows in early development can challenge metabolic functions and physiological responses to immune stress in adulthood, such as the systemic inflammation induced by lipopolysaccharide (LPS). The aim of this study was to investigate the long-term effects of post-natal over- and undernutrition on the anorexigenic effect of LPS and its association with neuronal
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Blueberry extracts antagonize Aβ25–35 neurotoxicity and exert a neuroprotective effect through MEK-ERK-BDNF/UCH-L1 signaling pathway in rat and mouse hippocampus Nutr. Neurosci. (IF 3.6) Pub Date : 2023-08-30 Long Tan, Han Zhang, Haiqiang Li, Shoudan Sun, Quanjun Lyu, Yugang Jiang
ABSTRACT Background: The neuroprotective potential of blueberry (BB) extracts against Alzheimer's disease (AD) has been previously hinted at, while its exact mechanism has remained largely enigmatic. Objective: Our study endeavored to unravel the impacts and mechanisms by which BB extracts ameliorated the learning and memory prowess of AD-afflicted mice, with a specific focus on the MEK-ERK pathway
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The relationship between adherence to the Mediterranean dietary pattern during early pregnancy and behavioral, mood and cognitive development in children under 1 year of age: a prospective cohort study Nutr. Neurosci. (IF 3.6) Pub Date : 2023-08-25 Bahareh Jabbarzadeh Ganjeh, Amin Mirrafiei, Ahmad Jayedi, Majid Mirmohammadkhani, Alireza Emadi, Farzaneh Ehsani, Sakineh Shab-Bidar
ABSTRACT Purpose To investigate the potential relationship between diet quality, represented by the Mediterranean diet score, during early pregnancy and behavioral, mood, and cognitive development in children under 1 year of age in a prospective cohort study in Iran. Methods 658 Iranian pregnant women and their infants participated in this prospective birth cohort study. The Mediterranean diet score
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Contrasting frontal cortical responses to food versus money rewards across BMI groups Nutr. Neurosci. (IF 3.6) Pub Date : 2023-08-21 Rachel Ginieis, Fu Yan, Elizabeth A. Franz, Mei Peng
ABSTRACT Previous research has linked obesity with an altered perception of rewards. This study aimed to contrast frontal cortical activities across body mass index (BMI) groups, in responding to differential rewards (monetary versus food). A total of 60 male participants (27.43 ± 6.07 years of age; 21 normal weight [BMI: 18.5–24.9 kg·m−2]; 20 overweight [BMI: 25.0–29.9 kg·m−2]; and 19 individuals
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A systematic review and meta-analysis of the omega-3 fatty acids effects on brain-derived neurotrophic factor (BDNF) Nutr. Neurosci. (IF 3.6) Pub Date : 2023-08-17 Somayeh Ziaei, Shooka Mohammadi, Motahareh Hasani, Mehrnaz Morvaridi, Andrej Belančić, Elnaz Daneshzad, Saleh A. K. Saleh, Heba M. Adly, Javad Heshmati
ABSTRACT Background Omega-3 fatty acids (omega-3 FAs) have attracted the attention of researchers because of their influence on circulatory levels of brain-derived neurotrophic factor (BDNF). Our objective was to review systematically and Meta-analyze randomized controlled trials (RCTs) to assess the effects of omega-3 FAs supplementation on serum BDNF concentration. Methods Scopus, PubMed, Web of
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Nutrition and schizophrenia: associations worthy of continued revaluation Nutr. Neurosci. (IF 3.6) Pub Date : 2023-08-11 Mimi Tang, Tingyu Zhao, Ting Liu, Ruili Dang, Hualin Cai, Ying Wang
ABSTRACT Background Accumulating evidence have shown that diet and nutrition play significant roles in mental illness, such as depression, anxiety and bipolar disorder. However, comprehensive evaluation of the relationship between nutrition and schizophrenia is lacking. Objective The present review aims to synthetic elaborate the associations between nutrition and schizophrenia. Relevant studies on
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Iron and n-3 fatty acid depletion, alone and in combination, during early development provoke neurochemical changes, anhedonia, anxiety and social dysfunction in rats Nutr. Neurosci. (IF 3.6) Pub Date : 2023-08-10 Erna T. Kemp, Lizelle Zandberg, Brian H. Harvey, Cornelius M. Smuts, Jeannine Baumgartner
ABSTRACT Objectives: Both iron and omega-3 (n-3) fatty acids (FA) play important roles in the development and functioning of the brain. We investigated the effects of n-3 FA and iron deficiencies, alone and in combination, during early development on behaviour and brain monoamines in rats. Methods: Using a 2-factorial design, female Wistar rats were randomly allocated to one of four diet groups: Control
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Naringenin: its chemistry and roles in neuroprotection Nutr. Neurosci. (IF 3.6) Pub Date : 2023-08-10 Ayomide Victor Atoki, Patrick Maduabuchi Aja, Tijjani Salihu Shinkafi, Erick Nyakundi Ondari, Chinaza Godswill Awuchi
ABSTRACT According to epidemiological research, as the population ages, neurological illnesses are becoming a bigger issue. Despite improvements in the treatment of these diseases, there are still widespread worries about how to find a long-lasting remedy. Several neurological diseases can be successfully treated with natural substances. As a result, current research has been concentrated on finding
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Associations between diet quality and migraine headaches: a cross-sectional study Nutr. Neurosci. (IF 3.6) Pub Date : 2023-08-05 Arghavan Balali, Elham Karimi, Maryam Kazemi, Amir Hadi, Gholamreza Askari, Fariborz Khorvash, Arman Arab
ABSTRACT Aims We evaluated associations between diet quality and migraine outcomes. Methods The current work represented a cross-sectional study on 262 patients with migraine (20–50 y). Diet quality was assessed using the standard healthy eating index 2015 (HEI-2015) and alternative healthy eating index 2010 (AHEI-2010). A validated 168-item food frequency questionnaire was used to assess dietary intake
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Dietary zinc intake in relation to migraine among adults: a cross sectional study of NHANES 1999–2004 Nutr. Neurosci. (IF 3.6) Pub Date : 2023-08-04 Heqing Zheng, Sheng Tian, Lanxiang Wu, Xianhui Zhong, Mingxu Liu, Xinping Yu, Yonggang Xie, Wei Wu
ABSTRACT Background Previous studies have revealed that an antioxidant diet is a protective factor against migraine. However, the association between zinc, an important antioxidant obtained from the diet, and migraine has received little attention. The purpose of this study was to explore the association between zinc intake with migraine. Methods The present study used cross-sectional data from individuals
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The gut microbial signatures of patients with lacunar cerebral infarction Nutr. Neurosci. (IF 3.6) Pub Date : 2023-08-04 Jiaying Ma, Huijia Xie, Chengxiang Yuan, Jie Shen, Jiaxin Chen, Qionglei Chen, Jiaming Liu, Qiuling Tong, Jing Sun
ABSTRACT Background Emerging evidence revealed that gut microbial dysbiosis is involved in the pathogenesis of multiple neurological diseases, but there is little available data on the relationship between gut microbiota and lacunar cerebral infarction (LCI). Methods Fecal samples from acute LCI patients (n = 65) and matched healthy controls (n = 65) were collected. The compositions and potential functions
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Independent and combined effects of astaxanthin and omega-3 on behavioral deficits and molecular changes in a prenatal valproic acid model of autism in rats Nutr. Neurosci. (IF 3.6) Pub Date : 2023-08-03 Emre Adiguzel, Nuh Mehmet Bozkurt, Gokhan Unal
ABSTRACT Objectives: Autism is a devastating neurodevelopmental disorder and recent studies showed that omega-3 or astaxanthin might reduce autistic symptoms due to their anti-inflammatory properties. Therefore, we investigated the effects of omega-3 and astaxanthin on the VPA-induced autism model of rats. Material and Methods: Female Wistar albino pups (n = 40) were grouped as control, autistic, astaxanthin
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Effect of a probiotic fermented milk supplementation on behavior and sleep Nutr. Neurosci. (IF 3.6) Pub Date : 2023-07-26 Samara M. Freitas, Beatriz Franco, Giulio Saragiotto, Milca A. Morais, Fernando M. Simabuco, Diogo T. Cunha, Andrea M. Esteves, Adriane E. C. Antunes
ABSTRACT This study attempted to analyze the effect of supplementing Wistar-Kyoto rats with fermented milk containing the probiotic Bifidobacterium animalis BB-12 and pomegranate juice on the microbiota-gut-brain axis of rats, with special focus on their behavior, sleep patterns, and response to stress. This study was divided into two experiments: (1) For the behavioral analysis the animals were divided
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The effect of vitamin D supplementation on the brain mapping and behavioral performance of children with ADHD: a double-blinded randomized controlled trials Nutr. Neurosci. (IF 3.6) Pub Date : 2023-07-25 Hamid Mirhosseini, Najmeh Maayeshi, Hadis Hooshmandi, Shadi Moradkhani, Mahdieh Hosseinzadeh
ABSTRACT Background Attention deficit hyperactivity disorder (ADHD) is one of the common neurodevelopmental diseases that are accompanied with EEG pattern changes and Low levels of 25-hydroxyvitamin D [25(OH)D]. Neurofeedback provides a feedback signal to alleviate brain wave abnormalities and offers an alternative therapy for ADHD. This study aimed to investigate the concomitant effects of Vitamin
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Effect of time restricted feeding on anthropometric measures, eating behavior, stress, serum levels of BDNF and LBP in overweight/obese women with food addiction: a randomized clinical trial Nutr. Neurosci. (IF 3.6) Pub Date : 2023-07-12 Hanieh Irani, Behnaz Abiri, Banafsheh Khodami, Zahra Yari, Maryam Lafzi Ghazi, Nima Hosseinzadeh, Atoosa Saidpour
ABSTRACT Background & aim Food addiction (FA) as a specific food-related behavior may play an essential role in the pathogenesis of obesity. Brain-derived neurotrophic factor (BDNF) and gut microbiota (GM) alterations probably through fasting are closely related to brain function, affecting eating behaviors and body weight management. This study aimed to evaluate the effect of time-restricted feeding
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A comprehensive examination of the evidence for whole of diet patterns in Parkinson's disease: a scoping review Nutr. Neurosci. (IF 3.6) Pub Date : 2023-07-10 Joanna Rees, Jillian Ryan, Manja Laws, Amanda Devine
ABSTRACT Both motor and non-motor symptoms of Parkinson’s disease (PD), a progressive neurological condition, have broad-ranging impacts on nutritional intake and dietary behaviour. Historically studies focused on individual dietary components, but evidence demonstrating ameliorative outcomes with whole-of-diet patterns such as Mediterranean and Mediterranean-DASH Intervention for Neurodegenerative
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Anthropometric indices, nutrient intakes and health-related characteristics of patients with multiple sclerosis: a cross-sectional study Nutr. Neurosci. (IF 3.6) Pub Date : 2023-07-10 Mahsa Moazen, Zahra Mousavi-Shirazi-Fard, Zohreh Mazloom, Sadegh Izadi, Maryam Ghaseminasab-Parizi
ABSTRACT Background Multiple sclerosis (MS) is accompanied by many health-related issues. This study aimed to evaluate the anthropometric indices, nutrient intakes and health-related characteristics of MS patients as well as their possible correlations. Methods This cross-sectional study was performed on 283 MS patients in Shiraz, Iran, during 2018–2019. Body mass index (BMI) and body composition were
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Effects of virgin coconut oil consumption on serum brain-derived neurotrophic factor levels and oxidative stress biomarkers in adults with metabolic syndrome: a randomized clinical trial Nutr. Neurosci. (IF 3.6) Pub Date : 2023-07-06 Elahe Mansouri, Somayyeh Asghari, Parinaz Nikooei, Mehdi Yaseri, Ali Vasheghani-Farahani, Mohammad Javad Hosseinzadeh-Attar
ABSTRACT Background and aim Metabolic syndrome is associated with health conditions and neurological disorders. Brain-derived neurotrophic factor (BDNF) plays a protective role on the nervous system. Decreased levels of BDNF have been shown in MetS and neurodegenerative diseases. There is promising evidence regarding the anti-inflammatory antioxidant, and neuroprotective properties of virgin coconut