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The Potential of Targeting Autophagy-Related Non-coding RNAs in the Treatment of Alzheimer’s and Parkinson’s Diseases Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2024-03-10 Abdolkarim Talebi Taheri, Zakieh Golshadi, Hamidreza Zare, Azam Alinaghipour, Zahra Faghihi, Ehsan Dadgostar, Zeinab Tamtaji, Michael Aschner, Hamed Mirzaei, Omid Reza Tamtaji, Fatemeh Nabavizadeh
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Unraveling the Neural Circuits: Techniques, Opportunities and Challenges in Epilepsy Research Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2024-03-06
Abstract Epilepsy, a prevalent neurological disorder characterized by high morbidity, frequent recurrence, and potential drug resistance, profoundly affects millions of people globally. Understanding the microscopic mechanisms underlying seizures is crucial for effective epilepsy treatment, and a thorough understanding of the intricate neural circuits underlying epilepsy is vital for the development
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Progress of Ferroptosis in Ischemic Stroke and Therapeutic Targets Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2024-02-23 Xinjuan Tian, Xiang Li, Mengtian Pan, Lele Zixin Yang, Yunman Li, Weirong Fang
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Iron Deposition in Parkinson’s Disease: A Mini-Review Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2024-02-23
Abstract Iron deposition is crucial pathological changes observed in patients with Parkinson's disease (PD). Recently, scientists have actively explored therapeutic approaches targeting iron deposition in PD. However, several clinical studies have failed to yield consistent results. In this review, we provide an overview of iron deposition in PD, from both basic research and clinical perspectives.
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A New Strategy for the Regulation of Neuroinflammation: Exosomes Derived from Mesenchymal Stem Cells Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2024-02-19 Ying Ge, Jingjing Wu, Li Zhang, Nanqu Huang, Yong Luo
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Roles of HOTAIR Long Non-coding RNA in Gliomas and Other CNS Disorders Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2024-02-16
Abstract HOX transcript antisense intergenic RNA (HOTAIR) is a long non-coding RNA (lncRNA) which is increasingly being perceived as a tremendous molecular mediator of brain pathophysiology at multiple levels. Epigenetic regulation of target gene expression carried out by HOTAIR is thorough modulation of chromatin modifiers; histone methyltransferase polycomb repressive complex 2 (PRC2) and histone
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Expression of CGRP in the Trigeminal Ganglion and Its Effect on the Polarization of Macrophages in Rats with Temporomandibular Arthritis Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2024-02-16 Junli Tao, Xiaohui Wang, Jie Xu
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Frequency and Focus of in Vitro Studies of Microglia-Expressed Cytokines in Response to Viral Infection: A Systematic Review Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2024-02-13 Diego A. Barrios-González, Santiago Philibert-Rosas, Iris E. Martínez-Juárez, Fernando Sotelo-Díaz, Verónica Rivas-Alonso, Julio Sotelo, Mario A. Sebastián-Díaz
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Disease-Associated Neurotoxic Astrocyte Markers in Alzheimer Disease Based on Integrative Single-Nucleus RNA Sequencing Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2024-02-12
Abstract Alzheimer disease (AD) is an irreversible neurodegenerative disease, and astrocytes play a key role in its onset and progression. The aim of this study is to analyze the characteristics of neurotoxic astrocytes and identify novel molecular targets for slowing down the progression of AD. Single-nucleus RNA sequencing (snRNA-seq) data were analyzed from various AD cohorts comprising about 210
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Neonatal IL-4 Over-Exposure is Accompanied by Macrophage Accumulation in Dura Mater After Instant Anti-inflammatory Cytokine Response in CSF Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2024-02-05 Ling Wang, Haoran Sha, Xiaoyi He, Yinyin Xie, Jiapeng Deng, Jiexuan Chen, Guoying Li, Junhua Yang
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Characterization of Retinal VIP-Amacrine Cell Development During the Critical Period Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2024-02-05 Xuhong Zhang, Xiaoyu Wang, Yanqing Li, Yingying Zhang, Hong Zhu, Chen Xie, Yudong Zhou, Ye Shen, Jianping Tong
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Treadmill Running Regulates Adult Neurogenesis, Spatial and Non-spatial Learning, Parvalbumin Neuron Activity by ErbB4 Signaling Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2024-01-29 Yandong Yi, Yuejin Zhang, Yuanlong Song, Yisheng Lu
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CircSKA3 is Associated With the Risk of Extracranial Artery Stenosis and Plaque Instability Among Ischemic Stroke Patients Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2024-01-10
Abstract Circular RNA circSKA3 (spindle and kinetochore-related complex subunit 3) has been identified as a prognostic factor in ischemic stroke. The objective of this study was to investigate the association of circSKA3 with the risk of extracranial artery stenosis (ECAS) and plaque instability in patients with ischemic stroke. We constructed a competing endogenous RNA (ceRNA) network regulated by
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Analysis and Regulatory Mechanisms of Platelet-Related Genes in Patients with Ischemic Stroke Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2024-01-04
Abstract It was found that ischemic stroke (IS) was associated with abnormal platelet activity and thrombosis. However, the potential significance of platelet-related genes (PRGs) in IS still needs to be more thorough. This study extracted IS-related transcriptome datasets from the Gene Expression Omnibus (GEO) database. The target genes were obtained by intersecting the differentially expressed genes
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Enlarged Perivascular Space and Index for Diffusivity Along the Perivascular Space as Emerging Neuroimaging Biomarkers of Neurological Diseases Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-12-29 Jun Zhang, Shengwen Liu, Yaqi Wu, Zhijian Tang, Yasong Wu, Yiwei Qi, Fangyong Dong, Yu Wang
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Discovery and Characterization of Ephrin B2 and EphB4 Dysregulation and Novel Mutations in Cerebral Cavernous Malformations: In Vitro and Patient-Derived Evidence of Ephrin-Mediated Endothelial Cell Pathophysiology Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-12-27 Julie Sesen, Aram Ghalali, Jessica Driscoll, Tyra Martinez, Adrien Lupieri, David Zurakowski, Sanda Alexandrescu, Edward R. Smith, Katie P. Fehnel
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Genetic Discrimination of Grade 3 and Grade 4 Gliomas by Artificial Neural Network Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-12-27 Aleksei A. Mekler, Dmitry R. Schwartz, Olga E. Savelieva
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Roles of Macrophages and Their Interactions with Schwann Cells After Peripheral Nerve Injury Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-12-27 Guanggeng Wu, Xiaoyue Wen, Rui Kuang, KoonHei Winson Lui, Bo He, Ge Li, Zhaowei Zhu
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Liposome-Mediated Anti-Viral Drug Delivery Across Blood–Brain Barrier: Can Lipid Droplet Target Be Game Changers? Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-12-20 Sourav Mondal, Sourish Ghosh
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Zika Virus Infection Alters the Circadian Clock Expression in Human Neuronal Monolayer and Neurosphere Cultures Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-12-23 Thaíse Yasmine Vasconcelos de Lima Cavalcanti, Morganna Costa Lima, Paula Bargi-Souza, Rafael Freitas Oliveira Franca, Rodrigo Antonio Peliciari-Garcia
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Patch-seq: Advances and Biological Applications Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-12-20 Mingting Shao, Wei Zhang, Ye Li, Lei Tang, Zhao-Zhe Hao, Sheng Liu
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Potential of Nano-Engineered Stem Cells in the Treatment of Multiple Sclerosis: A Comprehensive Review Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-12-17 Sushruta Ghosh, Gurjit Kaur Bhatti, Pushpender Kumar Sharma, Ramesh Kandimalla, Sarabjit Singh Mastana, Jasvinder Singh Bhatti
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Mutation in the TRKB Cholesterol Recognition Site that blocks Antidepressant Binding does not Influence the Basal or BDNF-Stimulated Activation of TRKB Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-12-17 Caroline Biojone, Cecilia Cannarozzo, Nina Seiffert, Cassiano R. A. F. Diniz, Cecilia A. Brunello, Eero Castrén, Plinio Casarotto
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Drivers of Chronic Pathology Following Ischemic Stroke: A Descriptive Review Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-12-19 Grant W. Goodman, Trang H. Do, Chunfeng Tan, Rodney M. Ritzel
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Elucidation of Site-Specific Ubiquitination on Chaperones in Response to Mutant Huntingtin Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-12-15 Prajnadipta Panda, Vivek Sarohi, Trayambak Basak, Prasad Kasturi
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Overexpress miR-132 in the Brain Parenchyma by a Non-invasive Way Improves Tissue Repairment and Releases Memory Impairment After Traumatic Brain Injury Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-12-17 Meng Jia, Xi Guo, Ru Liu, Lei Sun, Qun Wang, Jianping Wu
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Microglial Inflammatory Responses to SARS‐CoV‐2 Infection: A Comprehensive Review Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-12-15 Rajen Dey, Biswadev Bishayi
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Methyl-CpG-Binding Protein 2 Emerges as a Central Player in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-11-13 Arshad Mehmood, Suleman Shah, Ruo-Yi Guo, Arsalan Haider, Mengya Shi, Hamid Ali, Ijaz Ali, Riaz Ullah, Bin Li
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Neuromodulation Through Magnetic Fields Irradiation with AT-04 Improves Hyperalgesia in a Rat Model of Neuropathic Pain via Descending Pain Modulatory Systems and Opioid Analgesia Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-11-07 Tatsuro Kohno, Kaori Takaki, Kaori Kishita, Kazunori Mitsutake, Nozomu Tofuku, Iwao Kishita
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Genetic Features of Young and Aged Animals After Peripheral Nerve Injury: Implications for Diminished Regeneration Capacity Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-11-03 Weixiao Huang, Sheng Yi, Lili Zhao
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Research Progress on the Immune-Inflammatory Mechanisms of Posttraumatic Epilepsy Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-10-27 Yangbin Dang, Tiancheng Wang
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Screening Plasma Proteins for the Putative Drug Targets for Carpal Tunnel Syndrome Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-10-25 Bai-Xue Han, Tian-Ye Huang, Qi-Gang Zhao, Shan-Shan Yan, Qian Xu, Xin-Ling Ma, Yuan Luo, Yu-Fang Pei
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BDNF and Lactate as Modulators of Hippocampal CA3 Network Physiology Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-10-24 Ernesto Griego, Emilio J. Galván
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Antioxidant System and Endoplasmic Reticulum Stress in Cataracts Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-10-24 Xi Zhang, Bingqing Liu, Kevin Lal, Haihua Liu, Myhoa Tran, Manyu Zhou, Chimdindu Ezugwu, Xin Gao, Terry Dang, My-Lien Au, Erica Brown, Hongli Wu, Yan Liao
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Astroglial Connexin 43-Mediated Gap Junctions and Hemichannels: Potential Antidepressant Mechanisms and the Link to Neuroinflammation Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-10-24 Lan Lei, Ya-Ting Wang, Die Hu, Cong Gai, Yi Zhang
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In Vitro Models of Amyotrophic Lateral Sclerosis Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-10-23 Lijun Zhou, Wenzhi Chen, Shishi Jiang, Renshi Xu
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Quantitative Proteomics Characterization of the Effect and Mechanism of Trichostatin A on the Hippocampus of Type II Diabetic Mice Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-10-21 Wandi Wei, Qingning Zhang, Tingting Jin, Lin Zhu, Jialing Zhao, Fan Li, Song Zhao, Dezhi Kong, Jun Hao
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Decrease of Cellular Communication Network Factor 1 (CCN1) Attenuates PTZ-Kindled Epilepsy in Mice Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-10-21 Yiwei Liao, Sha Huang, Yuhu Zhang, Honghai Zhang, Haiting Zhao
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AQP4 is an Emerging Regulator of Pathological Pain: A Narrative Review Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-10-21 Binbin Zhu, Weijian Zhou, Chunqu Chen, Angyang Cao, Wenjun Luo, Changshun Huang, Jianhua Wang
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Animal Welfare Aspects in Planning and Conducting Experiments on Rodent Models of Subarachnoid Hemorrhage Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-10-20 Katrin Becker
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High Intensity Interval Training can Ameliorate Hypothalamic Appetite Regulation in Male Rats with Type 2 Diabetes: The Role of Leptin Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-10-12 Kayvan Khoramipour, Maryam Hossein Rezaei, Elham Madadizadeh, Mahdieh Sadat Hosseini, Zahra Soltani, Janis Schierbauer, Othmar Moser
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Retinal Changes in Parkinson’s Disease: A Non-invasive Biomarker for Early Diagnosis Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-10-13 Mohana Devi Subramaniam, P. Aishwarya Janaki, B. Abishek Kumar, Janani Gopalarethinam, Aswathy P. Nair, I. Mahalaxmi, Balachandar Vellingiri
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The Role of Oxidative Stress in Trisomy 21 Phenotype Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-10-11 Angelika Buczyńska, Iwona Sidorkiewicz, Adam Jacek Krętowski, Monika Zbucka-Krętowska
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The Combination of Citicoline and Nicotinamide Mononucleotide Induces Neurite Outgrowth and Mitigates Vascular Cognitive Impairment via SIRT1/CREB Pathway Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-10-09 Ning Zhao, Xiaofeng Zhu, Luyang Xie, Xin Guan, Leilei Tang, Guojun Jiang, Tao Pang
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Accelerated Extracellular Nucleotide Metabolism in Brain Microvascular Endothelial Cells in Experimental Hypercholesterolemia Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-10-06 Ewelina Czuba-Pakuła, Iwona Pelikant-Małecka, Grażyna Lietzau, Sławomir Wójcik, Ryszard T. Smoleński, Przemysław Kowiański
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Navigating the Landscape of MANF Research: A Scientometric Journey with CiteSpace Analysis Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-09-26 Caixia Zhang, Mi Zhang, Xueqin Cao, Bo Jiao, Wencui Zhang, Shangchen Yu, Xianwei Zhang
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Function of Long Noncoding RNAs in Glioma Progression and Treatment Based on the Wnt/β-Catenin and PI3K/AKT Signaling Pathways Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-09-25 Hanyun Li, Jilan Liu, Xianyun Qin, Jikui Sun, Yan Liu, Feng Jin
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The Neuroprotective Effects and Probable Mechanisms of Everolimus in a Rat Model of Intracerebral Hemorrhage Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-09-25 Shima Shirzad, Farzaneh Vafaee, Fatemeh Forouzanfar
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The Impact of Cerebral Ischemia on Antioxidant Enzymes Activity and Neuronal Damage in the Hippocampus Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-09-22 Jafar Sadeghzadeh, Leila Hosseini, Ahmad Mobed, Hamid Soltani Zangbar, Jaber Jafarzadeh, Jamshid Pasban, Parviz Shahabi
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N-Formyl-Methionyl-Leucyl-Phenylalanine Plays a Neuroprotective and Anticonvulsant Role in Status Epilepticus Model Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-09-24 Igor Santana de Melo, Robinson Sabino-Silva, Maisa Araújo Costa, Emília Rezende Vaz, Cassius Iury Anselmo-e-Silva, Thainá de Paula Soares Mendonça, Kellysson Bruno Oliveira, Fernanda Maria Araújo de Souza, Yngrid Mickaelli Oliveira dos Santos, Amanda Larissa Dias Pacheco, Jucilene Freitas-Santos, Douglas Carvalho Caixeta, Luiz Ricardo Goulart, Olagide Wagner de Castro
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Candidate Key Proteins in Tinnitus: A Bioinformatic Study of Synaptic Transmission in Spiral Ganglion Neurons Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-09-22 Johann Gross, Marlies Knipper, Birgit Mazurek
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Nrf2 and Ferroptosis: A New Research Direction for Ischemic Stroke Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-09-20 Xiaoman Deng, Wenming Chu, Hanrui Zhang, Yongjun Peng
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Pathophysiological Aspects and Therapeutic Armamentarium of Alzheimer’s Disease: Recent Trends and Future Development Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-09-19 Bhavarth P. Dave, Yesha B. Shah, Kunal G. Maheshwari, Kaif A. Mansuri, Bhadrawati S. Prajapati, Humzah I. Postwala, Mehul R. Chorawala
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Ultrastructural Changes in Hippocampal Region CA1 Neurons After Exposure to Permissive Hypercapnia and/or Normobaric Hypoxia Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-09-16 Pavel Tregub, Yuri Motin, Vladimir Kulikov, Pavel Kovzelev, Aleksandra Chaykovskaya, Irada Ibrahimli
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A Perfused In Vitro Human iPSC-Derived Blood–Brain Barrier Faithfully Mimics Transferrin Receptor-Mediated Transcytosis of Therapeutic Antibodies Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-09-12 Floriana Burgio, Carine Gaiser, Kevin Brady, Viviana Gatta, Reiner Class, Ramona Schrage, Laura Suter-Dick
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Liquid Biopsy in Low-Grade Glioma: A Systematic Review and a Proposal for a Clinical Utility Score Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-09-13 Luca Zanin, Alexandra Sachkova, Pier Paolo Panciani, Veit Rohde, Marco Maria Fontanella, Bawarjan Schatlo
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Activation of TRPV1 Channels Inhibits the Release of Acetylcholine and Improves Muscle Contractility in Mice Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-09-09 Arsenii Y. Arkhipov, Nikita S. Fedorov, Leniz F. Nurullin, Aydar N. Khabibrakhmanov, Marat A. Mukhamedyarov, Dmitry V. Samigullin, Artem I. Malomouzh
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Association of mTOR Pathway and Conformational Alterations in C-Reactive Protein in Neurodegenerative Diseases and Infections Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-09-04 Nitesh Kumar Poddar, Arshma Khan, Falak Fatima, Anshulika Saxena, Garima Ghaley, Shahanavaj Khan
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Effects of Ischemic Stroke on Interstitial Fluid Clearance in Mouse Brain: a Bead Study Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-08-27 Tuo Yang, Yang Sun, Qianqian Li, Nour Alraqmany, Feng Zhang
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Heterozygous FOXJ1 Mutations Cause Incomplete Ependymal Cell Differentiation and Communicating Hydrocephalus Cell. Mol. Neurobiol. (IF 4.0) Pub Date : 2023-08-24 Connie C. Hou, Danielle Li, Bethany C. Berry, Shaokuan Zheng, Rona S. Carroll, Mark D. Johnson, Hong Wei Yang