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Sequential Multilocus Repetitive Transcranial Magnetic Stimulation for Treatment of Tinnitus With and Without Comorbid Major Depressive Disorder Neuromodulation (IF 2.8) Pub Date : 2024-02-21 Zoe R. Berman, Cole Citrenbaum, Juliana Corlier, Andrew F. Leuchter, Robert L. Folmer, Michael K. Leuchter
Repetitive transcranial magnetic stimulation (rTMS) is a promising treatment for tinnitus, although outcomes are highly variable. We previously described a multilocus sequential rTMS treatment protocol for tinnitus involving stimulation of both prefrontal and auditory targets. In this study, we report results using this approach in an open-label treatment study of tinnitus with and without comorbid
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Electrical Diuretics: Dorsal Root Ganglion Stimulation to Increase Diuresis Neuromodulation (IF 2.8) Pub Date : 2024-02-15 Pawel Chodakowski, Adam Sokal, Agnieszka Manka, Bartlomiej Szwarc, Piotr Bogus, Richard Cornelussen, Michael Eggen, Lilian Kornet
Stimulation of diuresis is an essential component of heart failure treatment to reduce fluid overload. Over time, increasing doses of loop diuretics are required to achieve adequate urine output, and approximately 30% to 45% of patients develop diuretic resistance. We investigated the feasibility of affecting renal afferent sensory nerves by dorsal root ganglion neurostimulation as an alternative to
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Combination of Acute and Maintenance Esketamine Treatment With Adjunctive Long-Term Vagus Nerve Stimulation in Difficult-to-Treat Depression Neuromodulation (IF 2.8) Pub Date : 2024-02-10 Erhan Kavakbasi, Bernhard T. Baune
The antidepressant effect of N-methyl-D-aspartate antagonists is often short lasting, raising the question of the best maintenance strategy, which has remained unanswered. Vagus nerve stimulation (VNS) as a treatment option for refractory and chronic major depression was shown to reduce the need for maintenance treatment sessions in patients receiving electroconvulsive therapy. To our knowledge, there
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A Review of the Factors and Outcomes of Institutional Interdisciplinary Neuromodulation Committees: A Multicenter Experience Neuromodulation (IF 2.8) Pub Date : 2024-02-07 Scott G. Pritzlaff, Michael Jung, Naileshni Singh, Juliann Cho, Matthew Skoblar, Manoj Jagtiani, Ravi Prasad, Michael S. Leong, Vafi Salmasi
Neuromodulation represents one of the more advanced tools in the armamentarium of pain physicians. To optimize neuromodulation patient selection and management, an institutional interdisciplinary neuromodulation committee was created at each of two academic medical centers (University of California Davis [UCD] and Stanford University). The committee aims to collaboratively optimize neuromodulation
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Letter to the Editor Regarding: “Multiphase Spinal Cord Stimulation in Participants With Chronic Back or Leg Pain: Results of the BENEFIT-02 Randomized Clinical Trial” Neuromodulation (IF 2.8) Pub Date : 2024-02-05 Peng-Bo Zhou, Hong-Tao Sun
Abstract not available
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Letter to the Editor Regarding: “Long-Term Evaluation of Spinal Cord Stimulation in Patients With Painful Diabetic Polyneuropathy: An Eight-to-Ten-Year Prospective Cohort Study” Neuromodulation (IF 2.8) Pub Date : 2024-02-05 Peng-Bo Zhou, Hong-Tao Sun
Abstract not available
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Letter to the Editor Regarding: “Comparison of Spinal Cord Stimulation Trial Reporting Protocols and Long-Term Pain Relief Outcomes Following Implantation” Neuromodulation (IF 2.8) Pub Date : 2024-02-05 Peng-Bo Zhou, Hong-Tao Sun
Abstract not available
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Letter to the Editor Regarding: “A Novel, Paresthesia-Free Spinal Cord Stimulation Waveform for Chronic Neuropathic Low Back Pain: Six-Month Results of a Prospective, Single-Arm, Dose-Response Study” Neuromodulation (IF 2.8) Pub Date : 2024-02-05 Peng-Bo Zhou, Hong-Tao Sun
Abstract not available
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Response to: “Letter to the Editor Regarding: ‘A Novel, Paresthesia-Free Spinal Cord Stimulation Waveform for Chronic Neuropathic Low Back Pain: Six-Month Results of a Prospective, Single-Arm, Dose-Response Study’“ Neuromodulation (IF 2.8) Pub Date : 2024-02-05 Marc A. Russo
Abstract not available
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2024 Calendar of Events - February Neuromodulation (IF 2.8) Pub Date : 2024-02-05
Abstract not available
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Physicochemical Stability Study of the Morphine-Bupivacaine-Ziconotide Association Neuromodulation (IF 2.8) Pub Date : 2024-02-01 Jeremy Sorrieul, Julien Robert, Auriane Blanchet, Julien Gouju, Florent Bienfait, Sabrina Jubier Hamon, Denis Dupoiron, Catherine Devys
The aim of this study was to investigate the physicochemical stability of morphine-bupivacaine-ziconotide mixtures used in intrathecal analgesia in polypropylene syringes and intrathecal pumps. The stability study method was conceived according to International Council for Harmonisation guidelines. For propylene syringes, six different mixtures of morphine-bupivacaine and ziconotide were assessed over
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Current Waveforms in Spinal Cord Stimulation and Their Impact on the Future of Neuromodulation: A Scoping Review Neuromodulation (IF 2.8) Pub Date : 2024-01-04 Sayed E. Wahezi, Moorice A. Caparo, Ria Malhotra, Lakshman Sundaram, Kevin Batti, Prince Ejindu, Ratnakar Veeramachaneni, Magdalena Anitescu, Corey W. Hunter, Tahereh Naeimi, Fadi Farah, Lynn Kohan
Background Neuromodulation is a standard and well-accepted treatment for chronic refractory neuropathic pain. There has been progressive innovation in the field over the last decade, particularly in areas of spinal cord stimulation (SCS) and dorsal root ganglion stimulation. Improved outcomes using proprietary waveforms have become customary in the field, leading to an unprecedented expansion of these
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Factors Predicting Clinically Relevant Pain Relief After Spinal Cord Stimulation for Patients With Chronic Low Back and/or Leg Pain: A Systematic Review With Meta-Analysis and Meta-Regression Neuromodulation (IF 2.8) Pub Date : 2024-01-04 Ferdinand Bastiaens, Ilse H. van de Wijgert, Ewald M. Bronkhorst, Bert-Kristian W.P. van Roosendaal, Esther P.Z. van Heteren, Christopher Gilligan, Peter Staats, Jessica T. Wegener, Miranda L. van Hooff, Kris C.P. Vissers
Rationale To optimize results with spinal cord stimulation (SCS) for chronic low back pain (CLBP) and/or leg pain, including persistent spinal pain syndrome (PSPS), careful patient selection based on proved predictive factors is essential. Unfortunately, the necessary selection process required to optimize outcomes of SCS remains challenging. Objective This review aimed to evaluate predictive factors
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Efficacy of High-Voltage Pulsed Radiofrequency in Chronic Lumbosacral Radicular Pain: An Improved Tool? Neuromodulation (IF 2.8) Pub Date : 2024-01-04 Simone Vigneri, Gianfranco Sindaco
Abstract not available
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Efficacy of High-Voltage Pulsed Radiofrequency in Chronic Lumbosacral Radicular Pain: A Response Neuromodulation (IF 2.8) Pub Date : 2024-01-04 Burak Erken, Ipek S. Edipoglu
Abstract not available
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2024 Calendar of Events - January Neuromodulation (IF 2.8) Pub Date : 2024-01-04
Abstract not available
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Spinal Neuromodulation for Peripheral Arterial Disease of Lower Extremities: A Ten-Year Retrospective Analysis Neuromodulation (IF 2.8) Pub Date : 2024-01-01 Michael Kretzschmar, Udoka Okaro, Marcus Schwarz, Marco Reining, Thomas Lesser
Objective This long-term retrospective study evaluated the survival and amputation outcome of subjects who received neuromodulation therapy for the management of peripheral arterial disease (PAD). Materials and Methods The study reviews the health data of a single cohort of 51 patients who received spinal neuromodulation (spinal cord stimulation [SCS] or dorsal root ganglion stimulation [DRG-S]) for
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Disparities in Access to Deep Brain Stimulation and Responsive Neurostimulation Approaches to Drug-Resistant Epilepsy Neuromodulation (IF 2.8) Pub Date : 2023-12-28 Vishal Venkatraman, Brittany G. Futch, Alyssa Bartlett, Lexie Z. Yang, Hui-Jie Lee, Ben Shofty, Beth A. Parente, Shivanand P. Lad, Theresa L. Williamson, Shervin Rahimpour
Background Epilepsy affects 1% to 2% of the global population, and those who are resistant to medical treatment may be candidates for neuromodulation. In select populations, brain stimulation approaches including deep brain stimulation (DBS) and responsive neurostimulation (RNS) are used. Although studies have shown that patients from Black, Hispanic, lower income, and rural communities have less access
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The Effects of Transcranial Direct Current Stimulation and Exercise on Salivary S100B Protein Indicated Blood-Brain Barrier Permeability: A Pilot Study Neuromodulation (IF 2.8) Pub Date : 2023-12-27 Aidan Lewis, Constantino Toufexis, Chloe Goldsmith, Rebecca Robinson, Grace Howie, Ben Rattray, Andrew Flood
Objective This study aimed to assess the effect of transcranial direct current stimulation (tDCS) and exercise on blood-brain barrier (BBB) permeability in humans as assessed through the quantification of the salivary protein biomarker S100B. It was hypothesized that active tDCS would induce a significant increase in salivary S100B concentration when compared with sham stimulation and no stimulation
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Discrepancy Between Reported and Calculated Pain Reduction in Patients With Spinal Cord Stimulation Therapy and Lack of Agreement Between Patient Satisfaction and Degree of Pain Relief Neuromodulation (IF 2.8) Pub Date : 2023-12-27 Warren Southerland, Nasir Hussain, Ruan Qing, Puja Shankar, Sindhuja Surapaneni, James Burns, Syed Mahmood, Cyrus Yazdi, Mahmoud Abdel-Rasoul, Thomas T. Simopoulos, Jatinder S. Gill
Objectives This study aimed to determine agreement between reported percentage pain reduction (RPPR) and calculated percentage pain reduction (CPPR) in patients with percutaneous spinal cord stimulation (SCS) implants, and to correlate RPPR and CPPR with patient satisfaction. We also sought to determine which patient-reported outcome measures are most improved in patients with SCS. Materials and Methods
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Transcutaneous Electrical Acustimulation Improves Constipation Symptoms and Accelerates Colonic Transit in Patients With Slow Transit Constipation Through Autonomic Mechanism Neuromodulation (IF 2.8) Pub Date : 2023-12-21 Jingze Yang, Jinlu Guo, Ying Ba, Minxia Qiu, Fan Du, Jiande D.Z. Chen, Shi Liu
Objectives Nearly half of patients with slow transit constipation (STC) are not completely satisfied with their traditional remedies. We aimed to evaluate the therapeutic value and possible involved mechanism of transcutaneous electrical acustimulation (TEA) at ST36 in patients with STC. Materials and Methods Seventy patients with STC were randomly divided into TEA (n = 35) and sham-TEA (n = 35) to
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The Predicted Outcome of Spinal Cord Stimulation in Patients With a Psychopathological Disorder and Persistent Spinal Pain Syndrome Type 2: A Systematic Review From 2009 to 2021 Neuromodulation (IF 2.8) Pub Date : 2023-12-19 Tanja E. Hamm-Faber, Kris C.P. Vissers, Joke S. Kalkman, Frank G.A.M. van Haren, Hans J.A. Aukes, Yvonne Engels, Dylan J.H.A. Henssen
Objectives Psychologic screening is often included as a mandatory component of evaluation of the impact of psychopathology disorders on the predicted outcome of spinal cord stimulation (SCS) for patients with chronic pain due to persistent spinal pain syndrome type 2 (PSPS type 2). The conclusion of such screenings can influence the decision to offer SCS therapy to a patient. However, evidence on the
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Defining the Boundaries of Patient Perception in Spinal Cord Stimulation Programming Neuromodulation (IF 2.8) Pub Date : 2023-12-16 John Hatheway, Michael Yang, Michael Fishman, Michael Verdolin, Tory McJunkin, Steven Rosen, Sean Slee, Andrew Kibler, Kasra Amirdelfan
Objectives Recent developments in spinal cord stimulation (SCS) programming have initiated new modalities of imperceptible stimulation. However, the boundaries of sensory perception are not well defined. The BEnchtop NEuromodulation Following endIng of Trial study aimed to create a map of perceptual threshold responses across a broad range of SCS parameters and programming to inform subperception therapy
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Short-Term Effects of Gamma Stimulation on Neuroinflammation at the Tissue-Electrode Interface in Motor Cortex Neuromodulation (IF 2.8) Pub Date : 2023-12-13 Emily Boltcreed, Alpaslan Ersöz, Martin Han, George C. McConnell
Objectives The reliability of long-term neural recordings as therapeutic interventions for motor and sensory disorders is hampered by the brain tissue response. Previous work showed that flickering light at gamma frequencies (ie, 20–50 Hz) causes enhanced microglial recruitment in the visual cortex. The effects of gamma stimulation on glial cells surrounding implanted neural electrodes are not well
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Changes in Anticholinergic Burden in Parkinson’s Disease After Deep Brain Stimulation Neuromodulation (IF 2.8) Pub Date : 2023-12-12 Jocelyn Jiao, Barbara H. Brumbach, Nathan Hantke, Morgan Wilhelmi, Christian Bonilla, Delaram Safarpour
Objective This study aimed to evaluate the effect of deep brain stimulation (DBS) on anticholinergic burden in Parkinson’s disease (PD) and the association of anticholinergic burden with cognition. Materials and Methods A retrospective chart review in patients with PD who underwent bilateral subthalamic nucleus (STN) or globus pallidus internus (GPi) DBS from 2010 to 2020 reviewed medications with
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2023 Calendar of Events - December Neuromodulation (IF 2.8) Pub Date : 2023-12-05
Abstract not available
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Baclofen Stability up to One Year in In Vivo Intrathecal Infusion Pumps Neuromodulation (IF 2.8) Pub Date : 2023-12-03 Tommi K. Korhonen, Pauline Koopmans, Daan J. Touw, Sami Tetri
Objectives Commercial intrathecal baclofen treatment (ITBT) infusion pumps are recommended to be refilled within a maximum of 180 days, thus necessitating at least twice-yearly outpatient visits and refill injections. In particular, pumps with 40-mL reservoir volumes would allow much longer refill intervals. We investigated baclofen stability in active implanted ITBT infusion pumps in vivo with refill
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The Untold Story of Occipital Nerve Stimulation in Patients With Cluster Headache: Surgical Technique in Relation to Clinical Efficacy Neuromodulation (IF 2.8) Pub Date : 2023-11-30 Erkan Kurt, Linda Kollenburg, Robert van Dongen, Ruben Volkers, Wim Mulleners, Saman Vinke
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Deep Brain Stimulation for Guanine Nucleotide-Binding Protein Alpha-Activating Activity Polypeptide O-associated Dystonia: A Systematic Review and Meta-Analysis Neuromodulation (IF 2.8) Pub Date : 2023-11-24 Brecht Decraene, Sara Smeets, Daan Remans, Els Ortibus, Wim Vandenberghe, Bart Nuttin, Tom Theys, Philippe De Vloo
Objectives Guanine nucleotide-binding protein alpha-activating activity polypeptide O (GNAO1) syndrome, a rare congenital monogenetic disorder, is characterized by a neurodevelopmental syndrome and the presence of dystonia. Dystonia can be very pronounced and even lead to a life-threatening status dystonicus. In a small number of pharmaco-refractory cases, deep brain stimulation (DBS) has been attempted
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Ninety-Hz Spinal Cord Stimulation–Induced Analgesia Is Dependent on Active Charge Balance and Is Nonlinearly Related to Amplitude: A Sham-Controlled Behavioral Study in a Rodent Model of Chronic Neuropathic Pain Neuromodulation (IF 2.8) Pub Date : 2023-11-18 Lonne Heijmans, Tianhe C. Zhang, Rosana Esteller, Elbert A. Joosten
Background Ninety-Hz active-recharge spinal cord stimulation (SCS) applied at below sensory-threshold intensity, as used with fast-acting subperception therapy spinal cord stimulation, has been shown clinically to produce significant analgesia, but additional characterization is required to better understand the therapy. This preclinical study investigates the behavioral effect of multiple 90-Hz SCS
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Invasive Brain Computer Interface for Motor Restoration in Spinal Cord Injury: A Systematic Review Neuromodulation (IF 2.8) Pub Date : 2023-11-10 Jordan J. Levett, Lior M. Elkaim, Farbod Niazi, Michael H. Weber, Christian Iorio-Morin, Marco Bonizzato, Alexander G. Weil
Study design Systematic review of the literature. Objectives In recent years, brain-computer interface (BCI) has emerged as a potential treatment for patients with spinal cord injury (SCI). This is the first systematic review of the literature on invasive closed-loop BCI technologies for the treatment of SCI in humans. Materials and Methods A comprehensive search of PubMed MEDLINE, Web of Science,
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Is Response to a Pre-implant Diagnostic Peripheral Nerve Block Associated With Efficacy After Peripheral Nerve Stimulation Implantation? A Ten-Year Enterprise-Wide Analysis Neuromodulation (IF 2.8) Pub Date : 2023-11-10 Chelsey M. Hoffmann, Casey S. Butler, Matthew J. Pingree, Susan M. Moeschler, William D. Mauck, Ryan S. D’Souza
Objectives This study aimed to assess whether patient response to targeted diagnostic peripheral nerve block before peripheral nerve stimulator (PNS) device implantation is associated with efficacy after PNS implantation. Materials and Methods The electronic medical records from the Mayo Clinic Enterprise (three quarternary care medical centers and additional satellite medical centers) were reviewed
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Theta Burst Stimulation of the Human Motor Cortex Modulates Secondary Hyperalgesia to Punctate Mechanical Stimuli Neuromodulation (IF 2.8) Pub Date : 2023-11-10 Duncan J. Hodkinson, Marianne M. Drabek, JeYoung Jung, Sudheer T. Lankappa, Dorothee P. Auer
Objectives Many chronic pain conditions show evidence of dysregulated synaptic plasticity, including the development and maintenance of central sensitization. This provides a strong rationale for neuromodulation therapies for the relief of chronic pain. However, variability in responses and low fidelity across studies remain an issue for both clinical trials and pain management, demonstrating insufficient
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A Definition of Neuromodulation and Classification of Implantable Electrical Modulation for Chronic Pain Neuromodulation (IF 2.8) Pub Date : 2023-11-11 Eellan Sivanesan, Richard B. North, Marc A. Russo, Robert M. Levy, Bengt Linderoth, Salim M. Hayek, Sam Eldabe, Scott F. Lempka
Objectives Neuromodulation therapies use a variety of treatment modalities (eg, electrical stimulation) to treat chronic pain. These therapies have experienced rapid growth that has coincided with escalating confusion regarding the nomenclature surrounding these neuromodulation technologies. Furthermore, studies are often published without a complete description of the effective stimulation dose, making
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Donlin M. Long, MD, PhD (1934–2023) Neuromodulation (IF 2.8) Pub Date : 2023-11-07 Richard B. North
Abstract not available
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Seeing Is Believing: Photon Counting Computed Tomography Clearly Images Directional Deep Brain Stimulation Lead Segments and Markers After Implantation Neuromodulation (IF 2.8) Pub Date : 2023-11-03 James Manfield, Sheena Thomas, Marko Bogdanovic, Nagaraja Sarangmat, Charalambos Antoniades, Alexander L. Green, James J. FitzGerald
Background and Objectives Directional deep brain stimulation (DBS) electrodes are increasingly used, but conventional computed tomography (CT) is unable to directly image segmented contacts owing to physics-based resolution constraints. Postoperative electrode segment orientation assessment is necessary because of the possibility of significant deviation during or immediately after insertion. Photon-counting
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Chronic Sacral Nerve Stimulation Inhibits Visceral Hypersensitivity in Diarrhea–Predominant Irritable Bowel Syndrome Rats Model Neuromodulation (IF 2.8) Pub Date : 2023-11-04 Xiaojuan Guo, Changsheng Lei, Hanwei Liang, Jiaxu An, Yanbin Fang, Xiaolu Zhang, Zhiyan Wang, Chunhua Hu, Xuan Jiang
Objective Sacral nerve stimulation (SNS) is emerging as a novel treatment for irritable bowel syndrome (IBS). However, its effects are limited, and the underlying mechanisms remain largely unknown. Materials and Methods In this study, rats were divided into three groups (n = 12 rats per group): 1) the SNS group; 2) the sham SNS group (the sham group for short); and 3) the control group. The SNS and
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Intestinal Electrical Stimulation Synchronized With Intestinal Slow Wave Ameliorates Glucagon-Induced Hyperglycemia in Rats Neuromodulation (IF 2.8) Pub Date : 2023-10-27 Shiying Li, Hongbing Zhu, Jiande D.Z. Chen
Background Synchronized intestinal electrical stimulation (SIES), in which intestinal electrical stimulation (IES) is delivered in synchronization with the intrinsic slow wave of small intestine, was previously reported to be more potent in accelerating small intestine transit than IES delivered at fixed frequency and phase. We hypothesized that SIES is more potent in suppressing postprandial blood
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Transcutaneous Cervical Vagus Nerve Magnetic Stimulation in Patients With Traumatic Brain Injury: A Feasibility Study Neuromodulation (IF 2.8) Pub Date : 2023-10-20 Han Zhang, Yu Zhao, Yun Qu, Juan Du, Yi Peng
Objectives Transcutaneous vagus nerve stimulation has shown promising results in improving cognitive and motor function after stroke. However, to our knowledge, there have been no studies in the modulation of the cervical vagus nerve using repetitive transcranial magnetic stimulation (rTMS) in patients with traumatic brain injury (TBI) with cognitive dysfunction. Thus, we conducted a single-arm feasibility
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What Is in the Pipeline on Investigational Neuromodulation Techniques for Lower Urinary Tract Dysfunction: A Narrative Review Neuromodulation (IF 2.8) Pub Date : 2023-10-21 Stefano Parodi, Harry J. Kendall, Carlo Terrone, John P.F.A. Heesakkers
Objectives Overactive bladder (OAB) affects millions of patients worldwide. Its treatment is challenging but improves the patient’s quality of life. Besides standard techniques for neuromodulation (sacral and pudendal neuromodulation and posterior tibial nerve stimulation), several new techniques have been investigated to treat symptoms of refractory OAB. The purpose of the present review is to outline
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Incidence of Infections, Explantations, and Displacements/Mechanical Complications of Spinal Cord Stimulation During the Past Eight Years Neuromodulation (IF 2.8) Pub Date : 2023-10-19 Lisa Goudman, Maarten Moens, Sophie Kelly, Christopher Young, Julie G. Pilitsis
Objectives The overall awareness and potential of real-world data have drastically increased in the medical field, with potential implications for postmarket medical device surveillance. The goal of this study was to evaluate real-world data on incidence of infections, explantations, and displacements/mechanical complications of spinal cord stimulation (SCS) during the past eight years and to forecast
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Efficacy and Safety of Theta Burst vs Repetitive Transcranial Magnetic Stimulation for the Treatment of Depression: A Meta-Analysis of Randomized Controlled Trials Neuromodulation (IF 2.8) Pub Date : 2023-10-12 Chaomeng Liu, Li Li, Bing Li, Zhi Liu, Wenlong Xing, Kemeng Zhu, Wenqing Jin, Shuo Lin, Weihao Tan, Li Ren, Qinge Zhang
Objectives Theta burst stimulation (TBS) is more energy- and time-efficient than is standard repetitive transcranial magnetic stimulation (rTMS). However, further studies are needed to analyze TBS therapy for its efficacy and safety compared with standard rTMS in treating depression. The aim of this meta-analysis was to compare TBS therapy with standard rTMS treatment regarding their safety and therapeutic
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Patient-Centered Frameworks for Pain Neuromodulation Therapy: Overcoming Commercial and Regulatory Constraints to Optimize Therapy for Neural Interfaces Neuromodulation (IF 2.8) Pub Date : 2023-10-16 Shriya S. Srinivasan, Arun Venkatasubramanian, Richard North, Peter Konrad
Abstract not available
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Neuronavigation-Guided Implantation of a Surgical Spinal Cord Stimulation Lead in a Patient With Chronic Pain With Scoliosis and Severe Spinal Cord Rotation: A Technical Note Neuromodulation (IF 2.8) Pub Date : 2023-10-11 Abdulhamid Ciçek, Lisa Goudman
Abstract not available
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Update to “Efficacy and Safety of Cervical and High-Thoracic Dorsal Root Ganglion Stimulation Therapy for Complex Regional Pain Syndrome of the Upper Extremities” Neuromodulation (IF 2.8) Pub Date : 2023-10-05 Mateusz J. Graca, Timothy R. Lubenow
Abstract not available
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Does Temporary Externalization of Electrodes After Deep Brain Stimulation Surgery Result in a Higher Risk of Infection? Neuromodulation (IF 2.8) Pub Date : 2023-10-05 Joachim Runge, Johanna M. Nagel, Christian Blahak, Thomas M. Kinfe, Hans E. Heissler, Christoph Schrader, Marc E. Wolf, Assel Saryyeva, Joachim K. Krauss
Objectives Deep brain stimulation (DBS) is a well-established surgical therapy for movement disorders that comprises implantation of stimulation electrodes and a pacemaker. These procedures can be performed separately, leaving the possibility of externalizing the electrodes for local field potential recording or testing multiple targets for therapeutic efficacy. It is still debated whether the temporary
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Intraoperative Neurophysiological Monitoring During Spinal Cord Stimulation Surgery: A Systematic Review Neuromodulation (IF 2.8) Pub Date : 2023-10-04 Janine-Ai Schlaeppi, Raphael Schreen, Kathleen Seidel, Claudio Pollo
Objectives This study aims to describe the state of literature regarding the use of intraoperative neurophysiological monitoring (IONM) during spinal cord stimulator surgery. Materials and Methods A systematic review of the use of IONM during spinal cord stimulation (SCS) surgery was performed using the following three data bases: PubMed, Ovid MEDLINE, and Embase. Research techniques included systematic