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Quality Indicators of Endoscopic Retrograde Cholangiopancreatography in Korea. Gut Liver (IF 3.4) Pub Date : 2024-03-11 Hyung Ku Chon, Ki-Hyun Kim, Tae Jun Song, Dong-Won Ahn, Eaum Seok Lee, Yun Nah Lee, Yoon Suk Lee, Tae Joo Jeon, Chang Hwan Park, Kwang Bum Cho, Dong Wook Lee, Jin-Seok Park, Seung Bae Yoon, Kwang Hyun Chung, Jin Lee, Miyoung Choi
Endoscopic retrograde cholangiopancreatography (ERCP) is a procedure that requires significant experiences and skills and has various procedure-related complications, some of which can be severe and even result in the death of patients. Expanding ERCP availability has the advantage of increasing accessibility for patients. However, ERCP poses a substantial risk if performed without proper quality management
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Usefulness of Direct Peroral Cholangioscopy Using a Multibending Ultraslim Endoscope for the Management of Intrahepatic Bile Duct Lesions (with Videos). Gut Liver (IF 3.4) Pub Date : 2024-02-27 Won Myung Lee, Jong Ho Moon, Yun Nah Lee, Chang Wook Min, Il Sang Shin, Jun Ho Myeong, Hee Kyung Kim, Jae Kook Yang, Tae Hoon Lee
: Peroral cholangioscopy (POC) has been used to assess intrahepatic duct (IHD) lesions but with a limited role. A new multibending (MB) ultraslim endoscope has been designed to improve POC performance. We evaluated the usefulness of POC using the MB ultraslim endoscope for the management of IHD lesions.
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Daily Diet and Nutrition Risk Factors for Gastric Cancer Incidence in a Japanese Population. Gut Liver (IF 3.4) Pub Date : 2024-02-23 Ayaka Takasu, Takuji Gotoda, Sho Suzuki, Chika Kusano, Chiho Goto, Hideki Ishikawa, Hirofumi Kogure
: Nutritional factors associated with gastric cancer (GC) are not completely understood. We aimed to determine the effect of nutrient intake on the incidence of GC.
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Influence of Cytokine Genetic Polymorphisms in Helicobacter pylori-Associated Gastric Inflammation According to Sex in South Korea. Gut Liver (IF 3.4) Pub Date : 2024-02-23 Hee Jin Kim, Nayoung Kim, Jae Young Jang, Sihyun Kim, Jongchan Lee, Hyeon Jeong Oh
: The relationship between genetic polymorphisms and gastric inflammation remains unclear. This study aimed to evaluate the impact of genetic polymorphisms on Helicobacter pylori (HP)-associated gastritis according to sex.
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Molecular Activity of Inflammation and Epithelial-Mesenchymal Transition in the Microenvironment of Ulcerative Colitis. Gut Liver (IF 3.4) Pub Date : 2024-02-22 Yu Kyung Jun, Nayoung Kim, Hyuk Yoon, Ji Hyun Park, Hyung Kyung Kim, Yonghoon Choi, Ji Ae Lee, Cheol Min Shin, Young Soo Park, Dong Ho Lee
: The genetic expression in the active inflammatory regions is increased in ulcerative colitis (UC) with endoscopic activity. The aim of this study was to investigate the molecular activity of inflammation and tissue remodeling markers in endoscopically inflamed and uninflamed regions of UC.
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The Effect of Tegoprazan on the Treatment of Endoscopic Resection-Induced Artificial Ulcers: A Multicenter, Randomized, Active-Controlled Study. Gut Liver (IF 3.4) Pub Date : 2024-02-22 Byung-Wook Kim, Jong Jae Park, Hee Seok Moon, Wan Sik Lee, Ki-Nam Shim, Gwang Ho Baik, Yun Jeong Lim, Hang Lak Lee, Young Hoon Youn, Jun Chul Park, In-Kyung Sung, Hyunsoo Chung, Jeong Seop Moon, Gwang Ha Kim, Su Jin Hong, Hyuk Soon Choi
: Tegoprazan is a novel potassium-competitive acid blocker that has beneficial effects on acid-related disorders such as gastroesophageal reflux and peptic ulcer diseases. This study aimed to validate the effect of tegoprazan on endoscopic submucosal dissection (ESD)-induced artificial ulcers.
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Tumor-Derived Exosomal Circular RNA Pinin Induces FGF13 Expression to Promote Colorectal Cancer Progression through miR-1225-5p. Gut Liver (IF 3.4) Pub Date : 2024-02-22 Xianghui Liao, Tuhua Li, Li Yang, Haiwen Li, Weiru Li, Yuting Liu, Zhong Xie
: Colorectal cancer (CRC) is a common malignant tumor, and circular RNAs (circRNAs) are abnormally expressed in CRC. However, the function and underlying mechanism of circRNA pinin (circ-PNN; hsa_circ_0101802) in CRC remain unclear.
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The Association between Educational Attainment and the Risk of Nonalcoholic Fatty Liver Disease among Chinese Adults: Findings from the REACTION Study. Gut Liver (IF 3.4) Pub Date : 2024-02-22 Yuanyue Zhu, Long Wang, Lin Lin, Yanan Huo, Qin Wan, Yingfen Qin, Ruying Hu, Lixin Shi, Qing Su, Xuefeng Yu, Li Yan, Guijun Qin, Xulei Tang, Gang Chen, Shuangyuan Wang, Hong Lin, Xueyan Wu, Chunyan Hu, Mian Li, Min Xu, Yu Xu, Tiange Wang, Zhiyun Zhao, Zhengnan Gao, Guixia Wang, Feixia Shen, Xuejiang Gu, Zuojie Luo, Li Chen, Qiang Li, Zhen Ye, Yinfei Zhang, Chao Liu, Youmin Wang, Shengli Wu, Tao Yang
: Low educational attainment is a well-established risk factor for nonalcoholic fatty liver disease (NAFLD) in developed areas. However, the association between educational attainment and the risk of NAFLD is less clear in China.
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Real-World Risk of Gastrointestinal Bleeding for Direct Oral Anticoagulants and Warfarin Users: A Distributed Network Analysis Using a Common Data Model. Gut Liver (IF 3.4) Pub Date : 2024-02-22 Jae Myung Cha, Myoungsuk Kim, Hyeong Ho Jo, Won-Woo Seo, Sang Youl Rhee, Ji Hyun Kim, Gwang Ha Kim, Junseok Park
: Early studies on direct oral anticoagulants (DOACs) reported a higher risk of gastrointestinal bleeding (GIB) compared with warfarin; however, recent studies have reported a reduced risk. Therefore, this study was designed to evaluate the risk of GIB in users of DOAC and warfarin.
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Development of a Nomogram to Predict the Risk for Acute Necrotizing Pancreatitis. Gut Liver (IF 3.4) Pub Date : 2024-02-22 Junchao Zhang, Xiaxia Weng
: Necrotizing pancreatitis (NP) presents a more severe clinical trajectory and increased mortality compared to edematous pancreatitis. Prompt identification of NP is vital for patient prognosis. A risk prediction model for NP among Chinese patients has been developed and validated to aid in early detection.
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Immune-Enhancing Treatment among Acute Necrotizing Pancreatitis Patients with Metabolic Abnormalities: A Post Hoc Analysis of a Randomized Clinical Trial. Gut Liver (IF 3.4) Pub Date : 2024-02-15 Xiaofei Huang, Wenjian Mao, Xingxing Hu, Fengxia Qin, Hui Zhao, Aiping Zhang, Xinyu Wang, Christian Stoppe, Dandan Zhou, Lu Ke, Haibin Ni
: Metabolic syndrome is common in patients with acute pancreatitis and its components have been reported to be associated with infectious complications. In this post hoc analysis, we aimed to evaluate whether metabolic abnormalities impact the effect of immune-enhancing thymosin alpha-1 (Tα1) therapy in acute necrotizing pancreatitis (ANP) patients.
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Noninferiority Outcomes of Besifovir Compared to Tenofovir Alafenamide in Treatment-Naïve Patients with Chronic Hepatitis B. Gut Liver (IF 3.4) Pub Date : 2024-01-12 Tae Hyung Kim, Ji Hoon Kim, Hyung Joon Yim, Yeon Seok Seo, Sun Young Yim, Young-Sun Lee, Young Kul Jung, Jong Eun Yeon, Soon Ho Um, Kwan Soo Byun
: Besifovir dipivoxil maleate (BSV) and tenofovir alafenamide fumarate (TAF) have been recently approved in Korea as the initial antiviral agents for chronic hepatitis B (CHB). However, the real-world outcome data for these drugs remain limited. Therefore, we conducted a noninferiority analysis using real-world data to compare the clinical outcomes of the two nucleotide analogs in treatment-naïve patients
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Analysis of Recent Improvement of Survival Outcomes in Patients with Pancreatic Cancer Who Underwent Upfront Surgery. Gut Liver (IF 3.4) Pub Date : 2023-12-26 Jae Hyup Jung, Seung Hyun Won, Kwangrok Jung, Jun Suh Lee, Jong-Chan Lee, Jin Won Kim, Yoo-Seok Yoon, Jin-Hyeok Hwang, Ho-Seong Han, Jaihwan Kim
: Recently, patients with pancreatic cancer (PC) who underwent resection have exhibited improved survival outcomes, but comprehensive analysis is limited. We analyzed the trends of contributing factors.
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Outcomes of Palliative Chemotherapy for Ampulla of Vater Adenocarcinoma: A Multicenter Cohort Study. Gut Liver (IF 3.4) Pub Date : 2023-12-22 Dong Kee Jang, So Jeong Kim, Hwe Hoon Chung, Jae Min Lee, Seung Bae Yoon, Jong-Chan Lee, Dong Woo Shin, Jin-Hyeok Hwang, Min Kyu Jung, Yoon Suk Lee, Hee Seung Lee, Joo Kyung Park
: Palliative chemotherapy (PC) is not standardized for patients with advanced ampulla of Vater adenocarcinoma (AA). This multicenter, retrospective study evaluated first-line PC outcomes in patients with AA.
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The Possible Preventative Role of Lactate- and Butyrate-Producing Bacteria in Colorectal Carcinogenesis. Gut Liver (IF 3.4) Pub Date : 2023-11-30 Chin-Hee Song, Nayoung Kim, Ryoung Hee Nam, Soo In Choi, Jae Young Jang, Eun Hye Kim, Jina Choi, Yonghoon Choi, Hyuk Yoon, Sun Min Lee
: The gut microbiome has emerged as a key player that mechanistically links various risk factors to colorectal cancer (CRC) etiology. However, the role of the gut microbiome in CRC pathogenesis remains unclear. This study aimed to characterize the gut microbiota in healthy controls (HCs) and patients with colorectal adenoma (AD) and CRC in subgroups based on sex and age.
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Associations among the Duodenal Ecosystem, Gut Microbiota, and Nutrient Intake in Functional Dyspepsia. Gut Liver (IF 3.4) Pub Date : 2023-11-30 Sang Hoon Kim, Yura Choi, Jihong Oh, Eui Yeon Lim, Jung Eun Lee, Eun-Ji Song, Young-Do Nam, Hojun Kim
: Functional dyspepsia (FD) has long been regarded as a syndrome because its pathophysiology is multifactorial. However, recent reports have provided evidence that changes in the duodenal ecosystem may be the key. This study aimed to identify several gastrointestinal factors and biomarkers associated with FD, specifically changes in the duodenal ecosystem that may be key to understanding its pathophysiology
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Helicobacter pylori Infection Status and Gastric Tumor Incidence According to the Year of Birth. Gut Liver (IF 3.4) Pub Date : 2023-11-29 Jong Hwa Na,Sun-Young Lee,Jeong Hwan Kim,In-Kyung Sung,Hyung Seok Park
Background/Aims : The prevalence of Helicobacter pylori-naive status is increasing. Nonetheless, biennial gastroscopy is recommended for all Koreans aged 40 to 75 years. This study aimed to determine whether gastric cancer screening guidelines could be changed according to H. pylori infection status and year of birth. Methods : Koreans who underwent serum assays and gastroscopy for gastric cancer screening
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A Multicenter Survey of Percutaneous Endoscopic Gastrostomy in 2019 at Korean Medical Institutions. Gut Liver (IF 3.4) Pub Date : 2023-11-28 Jun Woo Park,Tae Gyun Kim,Kwang Bum Cho,Jeong Seok Kim,Jin Woong Cho,Jung Won Jeon,Sun Gyo Lim,Chan Gyoo Kim,Hong Jun Park,Tae Jun Kim,Eun Sun Kim,Su Jin Jeong,Yong Hwan Kwon,
Background/Aims : This study aimed to review the indications, methods, cooperation, complications, and outcomes of percutaneous endoscopic gastrostomy (PEG). Methods : Questionnaires were sent to 200 hospitals, of which 62 returned their questionnaires, with a response rate of approximately 30%. Descriptive statistics were calculated to analyze the responses to the questionnaires. Results : In 2019
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Appendicular Skeletal Muscle Mass to Visceral Fat Area Ratio Predicts Hepatic Morbidities. Gut Liver (IF 3.4) Pub Date : 2023-11-28 Eugene Han,Yong-Ho Lee,Sang Hoon Ahn,Bong-Soo Cha,Seung Up Kim,Byung-Wan Lee
Background/Aims : Reports on the association between sarcopenic visceral obesity and non-alcoholic fatty liver disease (NAFLD)-associated morbidities remain scarce. We investigated the association between sarcopenia and visceral obesity, and the influence of this association on hepatic and coronary comorbidities. Methods : The appendicular skeletal muscle mass to visceral fat area ratio (SV ratio)
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Differential Diagnosis of Thickened Gastric Wall between Hypertrophic Gastritis and Borrmann Type 4 Advanced Gastric Cancer. Gut Liver (IF 3.4) Pub Date : 2023-11-28 Jun-Young Seo,Do Hoon Kim,Ji Yong Ahn,Kee Don Choi,Hwa Jung Kim,Hee Kyong Na,Jeong Hoon Lee,Kee Wook Jung,Ho June Song,Gin Hyug Lee,Hwoon-Yong Jung
Background/Aims : Accurately diagnosing diffuse gastric wall thickening is challenging. Hypertrophic gastritis (HG), while benign, mimics the morphology of Borrmann type 4 advanced gastric cancer (AGC B-4). We compared the features of endoscopy and endoscopic ultrasonography (EUS) between them. Methods : We retrospectively reviewed patients who underwent EUS for gastric wall thickening between 2000
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Fecal Calprotectin at Postinduction Is Capable of Predicting Persistent Remission and Endoscopic Healing after 1 Year of Treatment with Infliximab in Pediatric Patients with Crohn's Disease. Gut Liver (IF 3.4) Pub Date : 2023-11-28 Yoo Min Lee,Eun Sil Kim,Sujin Choi,Hyo-Jeong Jang,Yu Bin Kim,So Yoon Choi,Byung-Ho Choe,Ben Kang
Background/Aims : The recent update on Selecting Therapeutic Targets in Inflammatory Bowel Disease initiative has added a decrease in fecal calprotectin (FC) to an acceptable range as an intermediate target for Crohn's disease (CD). We aimed to investigate whether postinduction FC could predict future persistent remission (PR) and endoscopic healing (EH) after 1 year of treatment with infliximab (IFX)
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Protecting Gastroenterologists through Rehabilitation Training: An Overlooked Area of Concern. Gut Liver (IF 3.4) Pub Date : 2023-11-15 Sun-Hye Ko,Myong Ki Baeg
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Challenges in and Opportunities for Electronic Health Record-Based Data Analysis and Interpretation. Gut Liver (IF 3.4) Pub Date : 2023-10-31 Michelle Kang Kim,Carol Rouphael,John McMichael,Nicole Welch,Srinivasan Dasarathy
Electronic health records (EHRs) have been increasingly adopted in clinical practices across the United States, providing a primary source of data for clinical research, particularly observational cohort studies. EHRs are a high-yield, low-maintenance source of longitudinal real-world data for large patient populations and provide a wealth of information and clinical contexts that are useful for clinical
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Risk Factors of Pneumocystis jirovecii Pneumonia in Patients with Inflammatory Bowel Disease: A Nationwide Population-Based Study. Gut Liver (IF 3.4) Pub Date : 2023-10-23 Jiyoung Yoon,Seung Wook Hong,Kyung-Do Han,Seung-Woo Lee,Cheol Min Shin,Young Soo Park,Nayoung Kim,Dong Ho Lee,Joo Sung Kim,Hyuk Yoon
Background/Aims : Pneumocystis jirovecii pneumonia (PJP) is a rare but potentially fatal infection. This study was conducted to investigate the risk factors for PJP in inflammatory bowel disease (IBD) patients. Methods : This nationwide, population-based study was conducted in Korea using claims data. Cases of PJP were identified in patients diagnosed with ulcerative colitis (UC) or Crohn's disease
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Endoscopic Features of Undifferentiated-Type Early Gastric Cancer in Patients with Helicobacter pylori-Uninfected or -Eradicated Stomachs: A Comprehensive Review. Gut Liver (IF 3.4) Pub Date : 2023-10-19 Yusuke Horiuchi, Toshiaki Hirasawa, Junko Fujisaki
Since the indications for endoscopic submucosal dissection have been expanded to include undifferentiated-type early gastric cancers, improvements in preoperative diagnostic ability have been an area of research. There are also concerns about the impact on the diagnosis of Helicobacter pylori infection. Based on our previous studies, in undifferentiated-type early gastric cancers, magnifying endoscopy
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Endoscopic Features of Undifferentiated-Type Early Gastric Cancer in Patients with Helicobacter pylori-Uninfected or -Eradicated Stomachs: A Comprehensive Review. Gut Liver (IF 3.4) Pub Date : 2023-10-19 Yusuke Horiuchi, Toshiaki Hirasawa, Junko Fujisaki
Since the indications for endoscopic submucosal dissection have been expanded to include undifferentiated-type early gastric cancers, improvements in preoperative diagnostic ability have been an area of research. There are also concerns about the impact on the diagnosis of Helicobacter pylori infection. Based on our previous studies, in undifferentiated-type early gastric cancers, magnifying endoscopy
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Clinical Practice Guideline for Percutaneous Endoscopic Gastrostomy. Gut Liver (IF 3.4) Pub Date : 2023-10-18 Chung Hyun Tae, Ju Yup Lee, Moon Kyung Joo, Chan Hyuk Park, Eun Jeong Gong, Cheol Min Shin, Hyun Lim, Hyuk Soon Choi, Miyoung Choi, Sang Hoon Kim, Chul-Hyun Lim, Jeong-Sik Byeon, Ki-Nam Shim, Geun Am Song, Moon Sung Lee, Jong-Jae Park, Oh Young Lee
With an aging population, the number of patients with difficulty swallowing due to medical conditions is gradually increasing. In such cases, enteral nutrition is administered through a temporary nasogastric tube. Long-term use of a nasogastric tube leads to various complications and a decreased quality of life. Percutaneous endoscopic gastrostomy (PEG) is the percutaneous placement of a tube into
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Challenges in Implementing Endoscopic Resection for T2 Colorectal Cancer. Gut Liver (IF 3.4) Pub Date : 2023-10-16 Katsuro Ichimasa,Shin-Ei Kudo,Ker-Kan Tan,Jonathan Wei Jie Lee,Khay Guan Yeoh
The current standard treatment for muscularis propria-invasive (T2) colorectal cancer is surgical colectomy with lymph node dissection. With the advent of new endoscopic resection techniques, such as endoscopic full-thickness resection or endoscopic intermuscular dissection, T2 colorectal cancer, with metastasis to 20%-25% of the dissected lymph nodes, may be the next candidate for endoscopic resection
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Progress and Clinical Applications of Crohn's Disease Exclusion Diet in Crohn's Disease. Gut Liver (IF 3.4) Pub Date : 2023-10-16 Duo Xu,Ziheng Peng,Yong Li,Qian Hou,Yu Peng,Xiaowei Liu
Crohn's disease is a chronic intestinal inflammatory disorder of unknown etiology. Although the pharmacotherapies for Crohn's disease are constantly updating, nutritional support and adjuvant therapies have recently gained more attention. Due to advancements in clinical nutrition, various clinical nutritional therapies are used to treat Crohn's disease. Doctors treating inflammatory bowel disease can
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Recent Advances in the Pathogenesis and Clinical Evaluation of Portal Hypertension in Chronic Liver Disease. Gut Liver (IF 3.4) Pub Date : 2023-10-16 Kohei Kotani,Norifumi Kawada
In chronic liver disease, hepatic stellate cell activation and degeneration of liver sinusoidal endothelial cells lead to structural changes, which are secondary to fibrosis and the presence of regenerative nodules in the sinusoids, and to functional changes, which are related to vasoconstriction. The combination of such changes increases intrahepatic vascular resistance and causes portal hypertension
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Optimal Follow-up of Incidental Pancreatic Cystic Lesions without Worrisome Features: Clinical Outcome after Long-term Follow-up. Gut Liver (IF 3.4) Pub Date : 2023-10-10 Dong-Won Ahn,Sang Hyub Lee,Jin Ho Choi,In Rae Cho,Dong Kee Jang,Woo Hyun Paik,Ji Bong Jeong,Ji Kon Ryu,Yong-Tae Kim
Background/Aims : The optimal duration and interval of follow-up for cystic lesions of the pancreas (CLPs) is not well established. This study was performed to investigate the optimal duration and interval of follow-up for CLPs in clinical practice. Methods : Patients with CLPs without worrisome features or high-risk stigmata underwent follow-up with computed tomography at 6, 12, 18, and 24 months
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Environmental and Microbial Factors in Inflammatory Bowel Disease Model Establishment: A Review Partly through Mendelian Randomization. Gut Liver (IF 3.4) Pub Date : 2023-10-10 Zesheng Lin, Wenjing Luo, Kaijun Zhang, Shixue Dai
Inflammatory bowel disease (IBD) is a complex condition resulting from environmental, microbial, immunologic, and genetic factors. With the advancement of Mendelian randomization research in IBD, we have gained new insights into the relationship between these factors and IBD. Many animal models of IBD have been developed using different methods, but few studies have attempted to model IBD by combining
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The Diagnostic Performance of Linked Color Imaging Compared to White Light Imaging in Endoscopic Diagnosis of Helicobacter pylori Infection: A Systematic Review and Meta-Analysis. Gut Liver (IF 3.4) Pub Date : 2023-10-06 Jae Gon Lee, In Kyung Yoo, Abdullah Ozgur Yeniova, Sang Pyo Lee
Recognizing Helicobacter pylori infection during endoscopy is important because it can lead to the performance of confirmatory testing. Linked color imaging (LCI) is an image enhancement technique that can improve the detection of gastrointestinal lesions. The purpose of this study was to compare LCI to conventional white light imaging (WLI) in the endoscopic diagnosis of H. pylori infection.
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Efficacy and Safety of Argon Plasma Coagulation for the Ablation of Barrett's Esophagus: A Systemic Review and Meta-Analysis. Gut Liver (IF 3.4) Pub Date : 2023-10-06 Marko Kozyk, Lohith Kumar, Kateryna Strubchevska, Manan Trivedi, Margaret Wasvary, Suprabhat Giri
Argon plasma coagulation (APC) is an alternate ablative method to radiofrequency ablation for the treatment of Barrett's esophagus (BE), and it is preferred due to its lower cost and widespread availability. The present meta-analysis aimed to analyze the safety and efficacy of APC for the management of BE.
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A Silent Outbreak of Hepatitis E Virus (HEV) Infection or False-Positive Reaction of Anti-HEV IgM after COVID-19 Vaccination? Epidemiological Investigation of an Outbreak in a Korean Factory Complex in 2022. Gut Liver (IF 3.4) Pub Date : 2023-10-06 Jeonghyeon Oh, Gwang Hyeon Choi, Yeonhwa Chang, Jina Kim, Kunhee Park, Hansol Yeom, Soonryu Seo, Jin Gwack, Sook-Hyang Jeong
To investigate a reported outbreak of presumed hepatitis E virus (HEV) infection in a Korean food manufacturing facility and to explore the association between anti-HEV immunoglobulin M (IgM) positivity and coronavirus disease 2019 (COVID-19) infection or vaccination.
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Mortality Risk Scoring System in Patients after Bleeding from Cancers in the Upper Gastrointestinal Tract. Gut Liver (IF 3.4) Pub Date : 2023-09-19 Hyun Min Kim, Donghoon Kang, Jun Young Park, Yu Kyung Cho, Myung-Gyu Choi, Jae Myung Park
: Risk scoring systems for upper gastrointestinal (UGI) bleeding have not been well validated for tumor bleeding. This study aimed to identify risk factors for mortality in patients with UGI cancer bleeding and to develop a predictive model.
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Utilization of an Automated Latex Agglutination Turbidity Assay for Assessing Gastric Mucosal Alteration during Helicobacter pylori Infection. Gut Liver (IF 3.4) Pub Date : 2023-09-18 Ayush Khangai,Junko Akada,Batsaikhan Saruuljavkhlan,Boldbaatar Gantuya,Dashdorj Azzaya,Khasag Oyuntsetseg,Duger Davaadorj,Tomohisa Uchida,Takashi Matsumoto,Yoshio Yamaoka
Background/Aims : A latex agglutination turbidity (LA) assay to test for serum antibodies has been approved in Japan and Korea for mass screening of Helicobacter pylori infection. In this study, we evaluated the LA assay for diagnosing H. pylori infection and predicting gastric mucosal changes in a Mongolian population. Methods : In total, 484 individuals were classified into H. pylori-positive (n=356)
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Is Tegoprazan-Based Triple Therapy Effective in Regions with High Rates of Clarithromycin Resistance? Gut Liver (IF 3.4) Pub Date : 2023-09-15 Hyun Ho Choi
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Should All Undifferentiated Early Gastric Cancer Patients Undergoing Noncurative Endoscopic Resection Be Sent to the Operating Room? Gut Liver (IF 3.4) Pub Date : 2023-09-15 Jung-Wook Kim,Albert C Kim
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Pretransplant Frailty on Postoperative Morbidity and Mortality after Liver Transplantation: Bystander or Upstander? Gut Liver (IF 3.4) Pub Date : 2023-09-15 Won-Mook Choi
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Evaluating the Self-Expandable Metal Stents Placement in Malignant Biliary Obstruction: A Deeper Dive. Gut Liver (IF 3.4) Pub Date : 2023-09-15 Kyong Joo Lee,Se Woo Park
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Factors Associated with Reaching Mid-Parental Height in Patients Diagnosed with Inflammatory Bowel Disease in Childhood and Adolescent Period. Gut Liver (IF 3.4) Pub Date : 2023-08-28 So Yoon Choi,Sujin Choi,Byung-Ho Choe,Jae Hong Park,Kwang-Hae Choi,Hae Jeong Lee,Ji Sook Park,Ji-Hyun Seo,Jae Young Kim,Hyo-Jeong Jang,Suk Jin Hong,Eun Young Kim,Yeoun Joo Lee,Ben Kang
Background/Aims The recent update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease initiative has added normal growth in children as an intermediate target in Crohn's disease and ulcerative colitis. We aimed to investigate factors associated with reaching mid-parental height (MPH) in patients diagnosed with inflammatory bowel disease in childhood and the adolescent period. Methods
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Chemoembolization versus Radiotherapy for Single Hepatocellular Carcinomas of ≤3 cm Unsuitable for Image-Guided Tumor Ablation. Gut Liver (IF 3.4) Pub Date : 2023-08-22 Jihye Lim, Euichang Kim, Sehee Kim, So Yeon Kim, Jin Hyoung Kim, Sang Min Yoon, Ju Hyun Shim
Local ablation therapy (LAT) is primarily recommended for solitary inoperable hepatocellular carcinomas (HCCs) of ≤3 cm in diameter. However, only two-thirds of uninodular small HCCs are suitable for LAT, and the second-best treatment option for managing these nodules is unclear. We aimed to compare the therapeutic outcomes of chemoembolization and radiotherapy in small HCCs unsuitable for LAT.
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Proposal of a Novel Serological Algorithm Combining FIB-4 and Serum M2BPGi for Advanced Fibrosis in Nonalcoholic Fatty Liver Disease. Gut Liver (IF 3.4) Pub Date : 2023-08-14 Sang Yi Moon,Yang Hyun Baek,Se Young Jang,Dae Won Jun,Ki Tae Yoon,Young Youn Cho,Hoon Gil Jo,Ae Jeong Jo
Background/Aims Noninvasive methods have become increasingly critical in the diagnosis of fibrosis in chronic liver diseases. Herein, we compared the diagnostic performance of serum Mac2 binding protein glycosylation isomer (M2BPGi) and other serological panels for fibrosis in patients with nonalcoholic fatty liver disease (NAFLD) and proposed an improved two-step diagnostic algorithm for advanced
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Clinical Outcome of Endoscopic Submucosal Dissection for Papillary Type Early Gastric Cancer: A Multicenter Study. Gut Liver (IF 3.4) Pub Date : 2023-08-14 Hyun-Deok Shin,Ki Bae Bang,Sun Hyung Kang,Hee Seok Moon,Jae Kyu Sung,Hyun Yong Jeong,Dong Kyu Lee,Ki Bae Kim,Sun Moon Kim,Seung Woo Lee,Dong Soo Lee,Young Sin Cho,Il-Kwun Chung,Ju Seok Kim
Background/Aims Papillary adenocarcinoma is classified to differentiated-type gastric cancer and is indicated for endoscopic submucosal dissection. However, due to its rare nature, there are limited studies on it. The purpose of this study was to determine the outcome of endoscopic submucosal dissection in patients with papillary-type early gastric cancer and to find the risk factors of lymph node
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Nonalcoholic Fatty Liver Disease as a Systemic Disease and the Need for Multidisciplinary Care. Gut Liver (IF 3.4) Pub Date : 2023-08-10 Masato Yoneda,Takashi Kobayashi,Michihiro Iwaki,Asako Nogami,Satoru Saito,Atsushi Nakajima
Nonalcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease, and there has been a rapid increase in cases worldwide. NAFLD is rapidly becoming the leading cause of hepatocellular carcinoma and is also associated with an increased risk of cardiovascular disease or exacerbation of other organ diseases, thus posing a significant health problem from both a medical and a
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Genetic and Metabolic Characteristics of Lean Nonalcoholic Fatty Liver Disease in a Korean Health Examinee Cohort. Gut Liver (IF 3.4) Pub Date : 2023-08-10 Huiyul Park,Eileen L Yoon,Goh Eun Chung,Eun Kyung Choe,Jung Ho Bae,Seung Ho Choi,Mimi Kim,Woochang Hwang,Hye-Lin Kim,Sun Young Yang,Dae Won Jun
Background/Aims The pathophysiology of lean nonalcoholic fatty liver disease (NAFLD) is unclear but has been shown to be associated with more diverse pathogenic mechanisms than that of obese NAFLD. We investigated the characteristics of genetic or metabolic lean NAFLD in a health checkup cohort. Methods This retrospective cross-sectional study analyzed single nucleotide polymorphism data for 6,939
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Cost-Utility Analysis of Non-Contrast Abbreviated Magnetic Resonance Imaging for Hepatocellular Carcinoma Surveillance in Cirrhosis. Gut Liver (IF 3.4) Pub Date : 2023-08-10 Pakanat Decharatanachart,Wirichada Pan-Ngum,Thoetchai Peeraphatdit,Natthaporn Tanpowpong,Pisit Tangkijvanich,Sombat Treeprasertsuk,Rungsun Rerknimitr,Roongruedee Chaiteerakij
Background/Aims Ultrasonography has a low sensitivity for detecting early-stage hepatocellular carcinoma (HCC) in cirrhotic patients. Non-contrast abbreviated magnetic resonance imaging (aMRI) demonstrated a comparable performance to that of magnetic resonance imaging without the risk of contrast media exposure and at a lower cost than that of full diagnostic MRI. We aimed to investigate the cost-effectiveness
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Research Progress of Central and Peripheral Corticotropin-Releasing Hormone in Irritable Bowel Syndrome with Comorbid Dysthymic Disorders. Gut Liver (IF 3.4) Pub Date : 2023-08-08 Yi Feng Liang,Xiao Qi Chen,Meng Ting Zhang,He Yong Tang,Guo Ming Shen
Irritable bowel syndrome (IBS) is considered a stress disorder characterized by psychological and gastrointestinal dysfunction. IBS patients not only suffer from intestinal symptoms such as abdominal pain, diarrhea, or constipation but also, experience dysthymic disorders such as anxiety and depression. Studies have found that corticotropin-releasing hormone plays a key role in IBS with comorbid dysthymic
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Perceptions of and Practices for the Management of Constipation: Results of a Korean National Survey. Gut Liver (IF 3.4) Pub Date : 2023-07-17 Young Sin Cho,Seon-Young Park,Jeong Eun Shin,Kyung Sik Park,Jung-Wook Kim,Tae Hee Lee,Seong-Eun Kim,Yoo Jin Lee,Han Seung Ryu,
Background/Aims Although guidelines exist regarding the evaluation and management of patients with chronic constipation (CC), little is known about real-world clinical practice patterns. This study aimed to evaluate the various practices used to manage CC patients in various clinical settings in South Korea. Methods A nationwide web-based survey was conducted, randomly selecting gastroenterologists
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Activin and Hepatocyte Growth Factor Promotes Colorectal Cancer Stemness and Metastasis through FOXM1/SOX2/CXCR4 Signaling. Gut Liver (IF 3.4) Pub Date : 2023-07-17 Hong Peng,Ting Ye,Lei Deng,Xiaofang Yang,Qingling Li,Jin Tong,Jinjun Guo
Background/Aims Cancer stem cells (CSCs) are believed to drive tumor development and metastasis. Activin and hepatocyte growth factor (HGF) are important cytokines with the ability to induce cancer stemness. However, the effect of activin and HGF combination treatment on CSCs is still unclear. Methods In this study, we sequentially treated colorectal cancer cells with activin and HGF and examined CSC
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Endoscopic Gallbladder Drainage Conversion versus Conservative Treatment Following Percutaneous Gallbladder Drainage in High-Risk Surgical Patients. Gut Liver (IF 3.4) Pub Date : 2023-07-17 Hyung Ku Chon,Seong-Hun Kim,Tae Hyeon Kim
Background/Aims There are no consensus guidelines for patients with acute cholecystitis undergoing percutaneous cholecystostomy who are unfit for interval cholecystectomy. The current study aimed to compare the clinical outcomes of endoscopic gallbladder drainage, i.e. conversion from percutaneous cholecystostomy (including endoscopic transpapillary gallbladder stenting and endoscopic ultrasound-guided
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Aerobic and Resistance Exercise: Synergistic Influence for Nonalcoholic Fatty Liver Disease. Gut Liver (IF 3.4) Pub Date : 2023-07-15 Ho Soo Chun
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Predictors of Severity of Acute Pancreatitis. Gut Liver (IF 3.4) Pub Date : 2023-07-15 Kyewhon Kim,Sung Bum Kim
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Unraveling Metabolic Dysfunction-Associated Fatty Liver Disease: Refining Sub-Phenotypes for Resolving Its Heterogeneity. Gut Liver (IF 3.4) Pub Date : 2023-07-15 Jung Gil Park
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The Efficacy and Safety of Endoscopic Resection for Early Gastric Cancer in Very Elderly Patients. Gut Liver (IF 3.4) Pub Date : 2023-07-15 Jin Lee
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Synergistic Preventive Effect of Aerobic and Resistance Exercises on Nonalcoholic Fatty Liver Disease. Gut Liver (IF 3.4) Pub Date : 2023-07-15 Ju-Yeon Cho,Won Sohn
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Sorafenib for 9,923 Patients with Hepatocellular Carcinoma: An Analysis from National Health Insurance Claim Data in South Korea. Gut Liver (IF 3.4) Pub Date : 2023-06-19 Sojung Han,Do Young Kim,Ho Yeong Lim,Jung-Hwan Yoon,Baek-Yeol Ryoo,Yujeong Kim,Kookhee Kim,Bo Yeon Kim,So Young Yi,Dong-Sook Kim,Do-Yeon Cho,Jina Yu,Suhyun Kim,Joong-Won Park
Background/Aims Sorafenib is the standard of care in the management of advanced hepatocellular carcinoma (HCC). The purpose of this study was to investigate the characteristics, treatment patterns and outcomes of sorafenib among HCC patients in South Korea. Methods This population-based retrospective, single-arm, observational study used the Korean National Health Insurance database to identify patients
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Factors Influencing the Diagnostic Performance of Repeat Endoscopic Ultrasound-Guided Fine-Needle Aspiration/Biopsy after the First Inconclusive Diagnosis of Pancreatic Solid Lesions. Gut Liver (IF 3.4) Pub Date : 2023-06-15 Jae Hee Cho,Jaihwan Kim,Hee Seung Lee,Su Jeong Ryu,Sung Ill Jang,Eui Joo Kim,Huapyong Kang,Sang Soo Lee,Tae Jun Song,Seungmin Bang
Background/Aims Endoscopic ultrasound-guided fine-needle aspiration/biopsy (EUS-FNA/B) is essential in diagnosing solid pancreatic lesions (SPLs), but without rapid on-site evaluation (ROSE), a repeat EUS-FNA/B is crucial for clarifying an inconclusive diagnosis. We aimed to evaluate factors associated with improved diagnostic performance of repeat EUS-FNA/B for initially inconclusive SPL diagnoses
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Enhancing Mural Nodules in the Main Pancreatic Duct of Main and Mixed Types of Intraductal Papillary Mucinous Neoplasms: Does Size Matter in Malignancy Risk? Gut Liver (IF 3.4) Pub Date : 2023-06-15 Hyung Ku Chon,Tae Jun Song,Kyoung-Hoon Yoo,Jun Seong Hwang,Myung-Hwan Kim,Eun Kwang Choi,Tae Hyeon Kim
Background/Aims Most guidelines recommend surgical resection of all main duct (MD) and mixed-type (MT) intraductal papillary mucinous neoplasms (IPMNs) in suitable patients. However, there is little evidence regarding the malignancy risk of enhancing mural nodules (EMNs) that are present only in the main pancreatic duct (MPD) in patients with MD- and MT-IPMNs. Therefore, this study aimed to identify