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Bleeding after endoscopic papillectomy and its risk factors: A single center experience of 196 cases Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2024-02-20 Jin Ho Choi, Won Chul Kim, Joo Kyung Park, Jong Kyun Lee, Kyu Taek Lee, Kwang Hyuck Lee
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Mirizzi syndrome: Problems and strategies Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2024-01-30 Jun Wu, Shuang-Yong Cai, Xu-Liang Chen, Zhi-Tao Chen, Shao-Hua Shi
Mirizzi syndrome is a serious complication of gallstone disease. It is caused by the impacted stones in the gallbladder neck or cystic duct. One of the features of Mirizzi syndrome is severe inflammation or dense fibrosis at the Calot's triangle. In our clinical practice, bile duct, branches of right hepatic artery and right portal vein clinging to gallbladder infundibulum are often observed due to
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Impact of nonalcoholic fatty liver disease on the risk of gallbladder polyps in lean and non-obese individuals: A cohort study Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2024-01-30 Nam Hee Kim, Ji Hun Kang, Hong Joo Kim
Background The association between non-obese or lean nonalcoholic fatty liver disease (NAFLD) and gallbladder polyps (GBPs) has not yet been evaluated. We aimed to determine whether NAFLD is an independent risk factor for the development of GBPs, even in non-obese and lean individuals. Methods We analyzed a cohort of 331 208 asymptomatic adults who underwent abdominal ultrasonography (US). The risk
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Tri-modal death distribution towards personalized management of intraductal papillary neoplasm of the bile duct patients: Every story has its own conclusion Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2024-01-20 Vor Luvira
Abstract not available
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Liver transplantation as an alternative for the treatment of perihilar cholangiocarcinoma: A critical review Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2024-01-20 Wellington Andraus, Francisco Tustumi, Alexandre Chagas Santana, Rafael Soares Nunes Pinheiro, Daniel Reis Waisberg, Liliana Ducatti Lopes, Rubens Macedo Arantes, Vinicius Rocha Santos, Rodrigo Bronze de Martino, Luiz Augusto Carneiro D'Albuquerque
Perihilar cholangiocarcinoma (phCCC) is a dismal malignancy. There is no consensus regarding the best treatment for patients with unresectable phCCC. The present review aimed to gather the current pieces of evidence for liver transplantation and liver resection as a treatment for phCCC and to build better guidance for clinical practice. The search was conducted in PubMed, Embase, Cochrane, and LILACS
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Timing of hepatectomy following the Omicron variant infection for vaccinated-patients: A retrospective cohort study Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2024-01-15 Wu-Gui Yang, Yu-Fu Peng, Yu-Bo Yang, Bo Li, Yong-Gang Wei, Fei Liu
Abstract not available
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Hepatic vein reconstruction during hepatectomy: A feasible and underused technique Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2024-01-15 Manish Ahuja, Kunal Joshi, Chris Coldham, Paulo Muiesan, Bobby Dasari, Manuel Abradelo, Ravi Marudanayagam, Darius Mirza, John Isaac, Dartlett Bartlett, Nikolaos A Chatzizacharias, Robert P Sutcliffe, Keith J Roberts
Abstract not available
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Meetings and Courses Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2024-01-04
Abstract not available
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A rare case of thymic carcinoma metastasize to liver Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-12-31 YF Jiang, J Wu, DY Chen
Abstract not available
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Comparison between models for detecting hepatocellular carcinoma in patients with chronic liver diseases of various etiologies: ASAP score versus GALAD score Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-12-30 Li-Yang Sun, Nan-Ya Wang, Yong-Kang Diao, Cun-Lin Yan, Zhu-Ping Fan, Lian-Hua Wei, Hui-Jun Li, Ming-Cheng Guan, Ming-Da Wang, Timothy M Pawlik, Wan-Yee Lau, Feng Shen, Guo-Yue Lv, Tian Yang
Background Diagnostic panels based on multiple biomarkers and clinical characteristics are considered more favorable than individual biomarker to diagnose hepatocellular carcinoma (HCC). Based on age, sex, alpha-fetoprotein (AFP), and protein induced by vitamin K absence II (PIVKA-II) with/without AFP-L3, ASAP and GALAD models are potential diagnostic panels. The diagnostic performances of these two
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Inadvertent perioperative hypothermia and surgical site infections after liver resection Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-12-30 Yi-De Zhou, Wen-Yuan Zhang, Guo-Hao Xie, Hui Ye, Li-Hua Chu, Yu-Qian Guo, Yi Lou, Xiang-Ming Fang
Background In the overall surgical population, inadvertent perioperative hypothermia has been associated with an increased incidence of surgical site infection (SSI). However, recent clinical trials did not validate this notion. This study aimed to investigate the potential correlation between inadvertent perioperative hypothermia and SSIs following liver resection. Methods This retrospective cohort
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Early-life exposure to gestational diabetes mellitus predisposes offspring to pediatric nonalcoholic fatty liver disease Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-12-30 Qian-Ren Zhang, Yan Dong, Jian-Gao Fan
Nonalcoholic fatty liver disease (NAFLD) has emerged as the prevailing chronic liver disease in the pediatric population due to the global obesity pandemic. Evidence shows that prenatal and postnatal exposure to maternal abnormalities leads to a higher risk of pediatric NAFLD through persistent alterations in developmental programming. Gestational diabetes mellitus (GDM) is a hyperglycemic syndrome
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Mitochondrial dysfunction in the pathogenesis of acute pancreatitis Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-12-30 Xia Chen, Rui Zhong, Bing Hu
The mechanism of cell damage during acute pancreatitis (AP) has not been fully elucidated, and there is still a lack of specific or effective treatments. Increasing evidence has implicated mitochondrial dysfunction as a key event in the pathophysiology of AP. Mitochondrial dysfunction is closely related to calcium (Ca2+) overload, intracellular adenosine triphosphate depletion, mitochondrial permeability
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Laparoscopic anatomic segmentectomy S8: Indocyanine green fluorescence approach and Glissonean approach (with videos) Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-12-30 Feng Gao, Jun-Jun Jia, Jun-Fang Deng, Zhou Shao, Shu-Sen Zheng
Abstract not available
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Liver transplantation and liver resection as alternative treatments for primary hepatobiliary and secondary liver tumors: Competitors or allies? Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-12-30 J, a, n, , L, e, r, u, t
Abstract not available
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Liver transplantation as an alternative for the treatment of non-resectable liver colorectal cancer: Advancing the therapeutic algorithm Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-12-30 Badi Rawashdeh, Richard Bell, Abdul Hakeem, Raj Prasad
Colorectal cancer is a leading cause of cancer-related mortality, with nearly half of the affected patients developing liver metastases. For three decades, liver resection (LR) has been the primary curative strategy, yet its applicability is limited to about 20% of cases. Liver transplantation (LT) for unresectable metastases was attempted unsuccessfully in the 1990s, with high rates of perioperative
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Mesenteric adipose tissue B lymphocytes promote intestinal injury in severe acute pancreatitis by mediating enteric pyroptosis Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-11-24 Qing Huang, Jia-Wen Liu, Hai-Bin Dong, Zheng-Jie Wei, Jin-Zhe Liu, Yu-Tang Ren, Xuan Jiang, Bo Jiang
Background Visceral adipose tissue (VAT) has been linked to the severe acute pancreatitis (SAP) prognosis, although the underlying mechanism remains unclear. It has been reported that pyroptosis worsens SAP. The present study aimed to verify whether mesenteric adipose tissue (MAT, a component of VAT) can cause secondary intestinal injury through the pyroptotic pathway. Methods Thirty-six male SD rats
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Efficacy of ginseng-based Renshenguben oral solution for cancer-related fatigue among patients with advanced-stage hepatocellular carcinoma: A prospective multicenter cohort study Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-11-21 Ming-Da Wang, Chen Yuan, Ke-Chun Wang, Nan-Ya Wang, Ying-Jian Liang, Hong Zhu, Xiang-Min Tong, Tian Yang
Background Cancer-related fatigue (CRF) is a common and debilitating symptom experienced by patients with advanced-stage cancer, especially those undergoing antitumor therapy. This study aimed to evaluate the efficacy and safety of Renshenguben (RSGB) oral solution, a ginseng-based traditional Chinese medicine, in alleviating CRF in patients with advanced hepatocellular carcinoma (HCC) receiving antitumor
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Comment on “Robotic surgery and liver transplantation: A single-center experience of 501 robotic donor hepatectomies” Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-11-19 Xiang-Yan Liu, Yun-Yang Xu, Ze Xiang, Shu-Sen Zheng
Abstract not available
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A successful case report of menstrual blood derived-mesenchymal stem cell-based therapy for Wilson's disease Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-11-07 Jia-Jun Wu, Yong Huang, Hai-Nv Gao, Guo-Ping Sheng
Abstract not available
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Retroaortic left renal vein associated to variations of liver vasculature and biliary system in a patient submitted to total pancreatectomy Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-11-07 Alessandro Fancellu, Mario Maiore, Lavinia Grasso, Miriam Ferrara, Alberto Porcu
Abstract not available
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Surgical techniques to prevent delayed gastric emptying after pancreaticoduodenectomy Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-11-07 Peng Duan, Lu Sun, Kai Kou, Xin-Rui Li, Ping Zhang
Background Delayed gastric emptying (DGE) is one of the most common complications after pancreaticoduodenectomy (PD). DGE represents impaired gastric motility without significant mechanical obstruction and is associated with an increased length of hospital stay, increased healthcare costs, and a high readmission rate. We reviewed published studies on various technical modifications to reduce the incidence
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Meetings and Courses Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-11-07
Abstract not available
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Comprehensive review of hepatocellular carcinoma with portal vein tumor thrombus: State of art and future perspectives Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-10-22 Paschalis Gavriilidis, Timothy M Pawlik, Daniel Azoulay
Background Despite advances in the diagnosis of patients with hepatocellular carcinoma (HCC), 70%-80% of patients are diagnosed with advanced stage disease. Portal vein tumor thrombus (PVTT) is among the most ominous signs of advanced stage disease and has been associated with poor survival if untreated. Data sources A systematic search of MEDLINE (PubMed), Embase, Cochrane Library and Database for
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Severe liver injury and clinical characteristics of occupational exposure to 2-amino-5-chloro-N,3-dimethylbenzamide: A case series Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-10-22 Meng-Xiao Feng, Hua Zou, Yuan-Qiang Lu
The 2-amino-5-chloro-N,3-dimethylbenzamide is a key intermediate in the synthesis of pesticides and pharmaceuticals. However, no literature currently exists on 2-amino-5-chloro-N,3-dimethylbenzamide poisoning in humans. This study aimed to reveal the health hazard of this chemical for humans and summarize the clinical characteristics of patients with occupational 2-amino-5-chloro-N,3-dimethylbenzamide
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Indications of pro-inflammatory cytokines in laparoscopic and open liver resection for early-stage hepatocellular carcinoma Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-10-20 Kevin Tak-Pan Ng, Li Pang, Jia-Qi Wang, Wong Hoi She, Simon Hing-Yin Tsang, Chung Mau Lo, Kwan Man, Tan To Cheung
Background : Our clinical practice of laparoscopic liver resection (LLR) had achieved better short-term and long-term benefits for patients with hepatocellular carcinoma (HCC) over open liver resection (OLR), but the underlying mechanisms are not clear. This study was to find out whether systemic inflammation plays an important role. Methods : A total of 103 patients with early-stage HCC under liver
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Ex vivo liver resection and auto-transplantation as an alternative for the treatment of liver malignancies: Progress and challenges Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-10-20 Xin Yang, Lu Lu, Wen-Wei Zhu, Yi-Feng Tao, Cong-Huan Shen, Jin-Hong Chen, Zheng-Xin Wang, Lun-Xiu Qin
Hepatectomy is still the major curative treatment for patients with liver malignancies. However, it is still a big challenge to remove the tumors in the central posterior area, especially if their location involves the retrohepatic inferior vena cava and hepatic veins. liver resection and auto-transplantation (ELRA), a hybrid technique of the traditional liver resection and transplantation, has brought
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Ferritinophagy: A new idea for liver diseases regulated by ferroptosis Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-10-20 Zi-Bing Qian, Jun-Feng Li, Wan-Yuan Xiong, Xiao-Rong Mao
The discovery of regulatory cell death has led to a breakthrough in the therapeutic field. Various forms of cell death, such as necrosis, apoptosis, pyroptosis, autophagy, and ferroptosis, play an important role in the development of liver diseases. In general, more than one form of cell death pathways is responsible for the disease state. Therefore, it is particularly important to study the regulation
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Diagnosis and therapy of tacrolimus toxicity in a liver transplant recipient during COVID-19 treatment Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-10-11 Feng Zhu, Yi-Ming Wang, Ming Ni, Yuan Liang, Jie-Hui Huang, Xue-Hao Wang, Feng Cheng, Ling Lu
Abstract not available
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Liver transplantation and resection in patients with hepatocellular cancer and portal vein tumor thrombosis: Feasible and effective? Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-10-10 P, r, a, s, h, a, n, t, , B, h, a, n, g, u, i
Patients with locally advanced hepatocellular cancer (HCC) and portal vein tumor thrombosis (PVTT) have a dismal prognosis since limited treatment options are available for them. In recent years, effective systemic therapy, and advances in the understanding of technicalities and effectiveness of ablative therapies especially radiotherapy, have given some hope to prolong survival in them. This review
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Animal models of hepatitis E infection: Advances and challenges Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-10-10 Ze Xiang, Xiang-Lin He, Chuan-Wu Zhu, Jia-Jia Yang, Lan Huang, Chun Jiang, Jian Wu, Chinese Consortium for the Study of Hepatitis E (CCSHE), Z Xiang, XL He, CW Zhu, JJ Yang, L Huang, C Jiang, J Wu
Hepatitis E virus (HEV) is one of the leading causes of acute viral hepatitis worldwide. Although most of HEV infections are asymptomatic, some patients will develop the symptoms, especially pregnant women, the elderly, and patients with preexisting liver diseases, who often experience anorexia, nausea, vomiting, malaise, abdominal pain, and jaundice. HEV infection may become chronic in immunosuppressed
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Pre-MASLD: Should it be defined separately? Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-10-10 Hang-Kai Huang, You-Ming Li, Cheng-Fu Xu
Abstract not available
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Meetings and Courses Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-09-29
Abstract not available
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TuBG1 promotes hepatocellular carcinoma via ATR/P53-apoptosis and cycling pathways Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-09-26 Yan Zhang, Zhen-Zhen Wang, An-Qi Han, Ming-Ya Yang, Li-Xin Zhu, Fa-Ming Pan, Yong Wang
As reported, γ-tubulin (TuBG1) is related to the occurrence and development of various types of malignant tumors. However, its role in hepatocellular cancer (HCC) is not clear. The present study was to investigate the relationship between TuBG1 and clinical parameters and survival in HCC patients. The correlation between TuBG1 and clinical parameters and survival in HCC patients was explored by bioinformatics
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The role of the gut microbiome in chronic liver diseases: Present insights and future outlook Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-09-04 Lu Jiang, Jian-Gao Fan
Abstract not available
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A robust genomic-based prognostic model for the assessment of cancer stemness and survival for patients with hepatocellular carcinoma Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-09-04 Cheng-Li Du, Shen-Yu Wei, Yun-Hao Chen, Kang-Jie Chen
Abstract not available
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A new prognostic model for drug-induced liver injury especially suitable for Chinese population Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-09-03 Yan-Fei Chen, Lan-Juan Li
Abstract not available
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Advanced hepatocellular carcinoma in a patient with neurofibromatosis type 1 and malignant peripheral nerve sheath tumor Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-08-23 Ahmad Alhaskawi, Yan-Zhao Dong, Xiao-Di Zou, Sohaib Hasan Abdullah Ezzi, Ze-Wei Wang, Hai-Ying Zhou, Sahar Ahmed Abdalbary, Hui Lu
Abstract not available
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Validation and performance of three scoring systems for predicting primary non-function and early allograft failure after liver transplantation Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-08-23 Yu Nie, Jin-Bo Huang, Shu-Jiao He, Hua-Di Chen, Jun-Jun Jia, Jing-Jing Li, Xiao-Shun He, Qiang Zhao
Background Primary non-function (PNF) and early allograft failure (EAF) after liver transplantation (LT) seriously affect patient outcomes. In clinical practice, effective prognostic tools for early identifying recipients at high risk of PNF and EAF were urgently needed. Recently, the Model for Early Allograft Function (MEAF), PNF score by King's College (King-PNF) and Balance-and-Risk-Lactate (BAR-Lac)
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Pancreatic cancer with gastrointestinal obstruction as an initial symptom Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-08-22 Jia-Ren Xu, Xing-Nan Wu, Yong-Qiang Si, Jin-Pu Yang, Xiao-Sun Liu
Abstract not available
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HSP110 aggravates ischemia-reperfusion injury after liver transplantation by promoting NF-κB pathway Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-08-22 Qing-Zhi Hu, Zhen-Rui Cao, Wei-Xiong Zheng, Min-Jie Zhao, Jun-Hua Gong, Cong Chen, Zhong-Jun Wu, Rui Tao
Background Ischemia-reperfusion injury (IRI) poses a significant challenge to liver transplantation (LT). The underlying mechanism primarily involves overactivation of the immune system. Heat shock protein 110 (HSP110) functions as a molecular chaperone that helps stabilize protein structures. Methods An IRI model was established by performing LT on Sprague-Dawley rats, and HSP110 was silenced using
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Visceral adipose tissue predicts severity and prognosis of acute pancreatitis in obese patients Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-08-22 Yuan Tian, Qing Huang, Yu-Tang Ren, Xuan Jiang, Bo Jiang
Acute pancreatitis is a common systemic inflammatory disease, manifested by a spectrum of severity, ranging from mild in the majority of patients to severe acute pancreatitis. Patients with severe acute pancreatitis suffer from severe local and systemic complications and organ failure, leading to a poor prognosis. The early recognition of the severe condition is important to improve prognosis. Obesity
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Pancreatic panniculitis as the first presentation of pancreatic ductal adenocarcinoma Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-08-22 Wei-Fang Zhu, Shan Fang, Jian-Jun Qiao
Abstract not available
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Clinical application of COVID-19 vaccine in liver transplant recipients Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-08-12 Feng-Chao Liu, Man Xie, Wei Rao
Background Solid organ transplant (SOT) activities, such as liver transplant, have been greatly influenced by the pandemic of coronavirus disease 2019 (COVID-19), a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Immunosuppressed individuals of liver transplant recipients (LTRs) tend to have a high risk of COVID-19 infection and related complications. Therefore, COVID-19
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Fat necrosis of liver in a patient with mixed type liver cirrhosis Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-08-12 Li-Fang Shao, Xiao-Min Shen, Wei Yu
Abstract not available
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Diagnosis and treatment of biliary mucinous cystic neoplasms: A single-center experience Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-08-12 Jun-Jun Jia, Ya-Fen Cheng, Mei-Bao Feng, Li Liu, Ming-Qi Shuai, Xiao-Dong Shen, Xiao-Feng Tang, Shu-Sen Zheng
Background Biliary mucinous cystic neoplasms (BMCNs) are rare hepatobiliary cystic tumors, which can be divided into noninvasive and invasive types. This study aimed to investigate the diagnosis, treatment, and prognosis of BMCNs in a large single center. Methods We analyzed 49 patients with BMCNs confirmed by postoperative pathology at the First Affiliated Hospital, Zhejiang University School of Medicine
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Liver transplantation as an alternative for the treatment of neuroendocrine liver metastasis: Appraisal of the current evidence Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-08-12 Philip C. Müller, Matthias Pfister, Dilmurodjon Eshmuminov, Kuno Lehmann
Liver transplantation (LT) for neuroendocrine liver metastases (NELM) is still in debate. Studies comparing LT with liver resection (LR) for NELM are scarce, as patient selection is heterogeneous and experience is limited. The goal of this review was to provide a critical analysis of the evidence on LT versus LR in the treatment of NELM. A scoping literature search on LT and LR for NELM was performed
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In vivo mouse models to study bile acid synthesis and signaling Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-08-12 Anisha Bhattacharya, Rulaiha E Taylor, Grace L Guo
The synthesis of bile acids (BAs) is carried out by complex pathways characterized by sequential chemical reactions in the liver through various cytochromes P450 (CYP) and other enzymes. Maintaining the integrity of these pathways is crucial for normal physiological function in mammals, encompassing hepatic and neurological processes. Studying on the deficiencies in BA synthesis genes offers valuable
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Propensity score matching analysis for clinical impact of braided-type versus laser-cut-type covered self-expandable metal stents for endoscopic ultrasound-guided hepaticogastrostomy Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-08-12 Mitsuki Tomita, Takeshi Ogura, Akitoshi Hakoda, Saori Ueno, Atsushi Okuda, Nobu Nishioka, Yoshitaro Yamamoto, Hiroki Nishikawa
To prevent stent migration during endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS), intra-scope channel release technique is important, but is unfamiliar to non-expert hands. The self-expandable metal stent (SEMS) is an additional factor to prevent stent migration. However, no comparative studies of laser-cut-type and braided-type during EUS-HGS have been reported. The aim of this study was
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Red cell distribution width-to-albumin ratio is a simple promising prognostic marker in acute cholangitis requiring biliary drainage Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-08-04 Fatih Acehan, Hüseyin Çamlı, Cagdas Kalkan, Mesut Tez, Burak Furkan Demir, Emin Altiparmak, Ihsan Ates
Background It is crucial to assess the severity of acute cholangitis (AC). There are currently several prognostic markers. However, the accuracies of these markers are not satisfied. The present study aimed to investigate the predictive value of the red cell distribution width (RDW)-to-albumin ratio (RAR) for the prognosis of AC. Methods We retrospectively evaluated consecutive patients diagnosed with
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Are outcomes for emergency index-admission laparoscopic cholecystectomy performed by hepatopancreatobiliary surgeons better compared to non-hepatopancreatobiliary surgeons? A 10-year audit using 1:1 propensity score matching Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-08-03 Kai Siang Chan, Samantha Baey, Vishal G Shelat, Sameer P Junnarkar
Background Emergency index-admission cholecystectomy (EIC) is recommended for acute cholecystitis in most cases. General surgeons have less exposure in managing “difficult” cholecystectomies. This study aimed to compare the outcomes of EIC between hepatopancreatobiliary (HPB) versus non-HPB surgeons. Methods This is a 10-year retrospective audit on patients who underwent EIC from December 2011 to March
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Prevalence and risk factors for impaired renal function among Asian patients with nonalcoholic fatty liver disease Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-08-03 Chao Sun, George Boon-Bee Goh, Wan-Cheng Chow, Wah-Kheong Chan, Grace Lai-Hung Wong, Wai-Kay Seto, Yi-Hsiang Huang, Han-Chieh Lin, I-Cheng Lee, Hye Won Lee, Seung Up Kim, Vincent Wai-Sun Wong, Jian-Gao Fan
Background Nonalcoholic fatty liver disease (NAFLD) is associated with impaired renal function, and both diseases often occur alongside other metabolic disorders. However, the prevalence and risk factors for impaired renal function in patients with NAFLD remain unclear. The objective of this study was to identify the prevalence and risk factors for renal impairment in NAFLD patients. Methods All adults
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Split liver transplantation with complicated portal vein variations in graft Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-08-03 Zhao-Xin Shang, Qi-Jian Yu, Fang-Zhou Luo, Li Zhuang, Shu-Sen Zheng, Zhe Yang
Abstract not available
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Recent advances in promising drugs for primary prevention of gastroesophageal variceal bleeding with cirrhotic portal hypertension Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-08-03 Ji-Yao Sheng, Zi-Fan Meng, Qiao Li, Yong-Sheng Yang
Background Gastroesophageal variceal bleeding is one of the most severe complications of patients with cirrhosis. Although primary prevention drugs, including non-selective β-blockers, have effectively reduced the incidence of bleeding, their efficacy is limited due to side effects and related contraindications. With recent advances in precision medicine, precise drug treatment provides better treatment
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Low skeletal muscle mass and high visceral adiposity are associated with recurrence of acute cholecystitis after conservative management: A propensity score-matched cohort study Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-07-25 Yudai Koya, Michihiko Shibata, Yuki Maruno, Yoshitaka Sakamoto, Shinji Oe, Koichiro Miyagawa, Yuichi Honma, Masaru Harada
Background Recurrent acute cholecystitis (RAC) can occur after non-surgical treatment for acute cholecystitis (AC), and can be more severe in comparison to the first episode of AC. Low skeletal muscle mass or adiposity have various effects in several diseases. We aimed to clarify the relationship between RAC and body parameters. Methods Patients with AC who were treated at our hospital between January
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Pancreatic giant malignancy simulating a gastrointestinal stromal tumor Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-07-23 Ben-Jie Liu, Chen-Hui Jin, Yan-Lun Guo, Zhi-Gang Ke, Jun-Jun Huang, Lin-Ping Cao
Abstract not available
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Intraoperative cholangio-ultrasonography (IOCUS) during hepatectomy with resection of the biliary confluence: An effective alternative to intraoperative cholangiography Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-07-23 Daniele Del Fabbro, Fabio Procopio, Jacopo Galvanin, Guido Costa, Simone Famularo, Angela Palmisano, Matteo Donadon, Guido Torzilli
Abstract not available
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Liver transplantation as an alternative for the treatment of intrahepatic cholangiocarcinoma: Past, present, and future directions Hepatob. Pancreat. Dis. Int. (IF 3.3) Pub Date : 2023-07-23 Sudha Kodali, Ashton A Connor, Souhail Thabet, Elizabeth W Brombosz, R Mark Ghobrial
Intrahepatic cholangiocarcinoma (iCCA) is a rare biliary tract cancer with high mortality rate. Complete resection of the iCCA lesion is the first choice of treatment, with good prognosis after margin-negative resection. Unfortunately, only 12%-40% of patients are eligible for resection at presentation due to cirrhosis, portal hypertension, or large tumor size. Liver transplantation (LT) offers margin-negative