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Respiratory adenovirus infections in children: a focus on Africa. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2024-03-01 Marieke M van der Zalm, Nadia A Sam-Agudu, Lilly M Verhagen
Lower respiratory tract infections (LRTIs) are an important cause of child morbidity and mortality globally, especially in children under the age of 5 years in Africa. Respiratory viruses, including human adenoviruses (HAdVs), are common causes of LRTIs in children. This review aims to shed light on the epidemiology, clinical manifestations, sequelae, and treatment options specific to adenovirus respiratory
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Updates on the clinical integration of point-of-care ultrasound in pediatric emergency medicine. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2024-02-26 Michelle Sin Lee, Danielle Sweetnam-Holmes, Gili Palnizky Soffer, Maya Harel-Sterling
There is expanding evidence for point-of-care ultrasound (POCUS) use in pediatric emergency medicine - this review highlights the benefits and challenges in the clinical integration of high-yield POCUS applications. Specifically, it will delve into POCUS applications during resuscitations, controversies of Focused Assessment with Sonography for Trauma (FAST) in pediatric trauma, POCUS-guided procedures
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Precision care in the treatment of pediatric asthma. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2024-02-26 Lina Mahmood, Sevdenur Keskin, Akilah A Jefferson
Precision medicine in pediatric asthma involves identification of asthma phenotypes, genetic markers, biomarkers, and biologics that target specific pathways. This review includes a discussion of the efficacy of currently approved biologics for pediatric asthma and most recent advances in biomarker/phenotype identification and genetic associations that affect asthma care.
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Highly effective cystic fibrosis transmembrane conductance (regulator) modulator therapy: shifting the curve for most while leaving some further behind. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2024-02-16 Stanford W Chun, Maya E Somers, Elizabeth B Burgener
Traditional cystic fibrosis (CF) care had been focused on early intervention and symptom mitigation. With the advent of highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapy (HEMT), in particular, the approval of elexacaftor/tezacaftor/ivacaftor in 2019, there has been a dramatic improvement in outcomes in CF. The purpose of this article is to review the benefits
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Updates on respiratory syncytial virus prophylaxis: the past, present and future. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2024-02-14 Anne Coates, Christy Sadreameli
Human respiratory syncytial virus (RSV) causes acute respiratory infection in individuals of all age groups. It is the most common pathogen identified in infants and young children with acute lower respiratory infection. Although most infants and young children experience mild, cold-like symptoms, some infants develop severe lower respiratory tract disease such as pneumonia and bronchiolitis that may
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Approach to acute agitation in the pediatric emergency department. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2024-02-01 Ashley A Foster, Mohsen Saidinejad, Joyce Li
The complexity of pediatric mental and behavioral health (MBH) complaints presenting to emergency departments (EDs) is increasing at an alarming rate. Children may present with agitation or develop agitation during the ED visit. This causes significant distress and may lead to injury of the child, caregivers, or medical staff. This review will focus on providing safe, patient-centered care to children
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Recent advances in the prevention of respiratory syncytial virus in pediatrics. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2024-01-26 Madeline A Lipp, Kerry M Empey
Respiratory syncytial virus (RSV) is a ubiquitous virus and the leading cause of pediatric hospitalization in the United States. Prevention strategies are key for reducing the burden of RSV. Several new agents aimed at preventing RSV in infants and children were FDA-approved in 2023, and many more are in the development pipeline. This review highlights new developments in RSV prevention in pediatric
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All shook up: how the COVID-19 pandemic rocked pediatric asthma care. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2024-01-23 Carl Kaplan, Alexa H Christophides, Alexandra M Kranidis, Ashley L Saint-Fleur, Catherine Kier
Asthma management is a crucial aspect of public health. The landscape of asthma management underwent significant change in the wake of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. These changes greatly affected existing patients, individuals suffering with undiagnosed illness, providers, and the healthcare system as a whole.
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Malaria prevention in children: an update. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2024-01-23 DeAnna J Friedman-Klabanoff, Dennis Adu-Gyasi, Kwaku Poku Asante
Malaria cases and deaths decreased from 2000 to 2015 but remain increased since 2019. Several new developments and strategies could help reverse this trend. The purpose of this review is to discuss new World Health Organization (WHO) guidelines and recent research on malaria prevention in children.
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Clinical updates in inborn errors of immunity: a focus on the noninfectious clinical manifestations. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2024-01-23 Emily Campbell, Marcus S Shaker, Kelli W Williams
In the last 5 years, several new inborn errors of immunity (IEI) have been described, especially in the areas of immune dysregulation and autoinflammation. As a result, the clinical presentation of IEIs has broadened. We review the heterogeneous presentation of IEIs and detail several of the recently described IEIs with a focus on the noninfectious manifestations commonly seen.
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Cholera outbreaks among children in sub-Saharan Africa. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2024-01-18 Agozie C Ubesie, Chioma L Odimegwu, Echezona Edozie Ezeanolue
We review current knowledge on the burden, impact and prevention of cholera among children who bear the brunt of cholera outbreaks in sub-Saharan Africa.
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Overview of invasive fungal infections in children in South America - the threat of resistant Candida species and the role of climate change in the new geographic distribution of endemic systemic mycosis. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2024-01-16 Silvia Nunes Szente Fonseca
Invasive fungal infection (IFI) in children is a growing problem with crescent morbidity and mortality, well recognized in developed countries, affecting mainly immunocompromised children, including neonates and children in intensive care units. The burden of IFI in South American children is less well comprehended. In addition, the current epidemiology of endemic systemic mycoses in children may have
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Updates in hyponatremia and hypernatremia. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2024-01-05 Leslie Saba, Christian Hanna, Ana L Creo
Hyponatremia and hypernatremia are commonly encountered electrolyte abnormalities that require timely and careful intervention, as they can be associated with significant morbidity and mortality.
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Tick-borne infections in children in North America. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2024-01-04 Emma Taylor-Salmon, Eugene D Shapiro
Because both incidence and awareness of tick-borne infections is increasing, review of major infections and recent advances related to their diagnosis and management is important.
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Community-acquired bacterial pneumonia in children: an update on antibiotic duration and immunization strategies. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2024-01-04 Edward Lyon, Liset Olarte
This review is structured to update clinicians on the epidemiology, antibiotic treatment, and prevention of pediatric bacterial pneumonia. The review provides information regarding the current research on antibiotic management for bacterial pneumonia and the newest immunization recommendations to prevent pneumococcal pneumonia and other respiratory infections.
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Outpatient respiratory syncytial virus infections and novel preventive interventions. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-12-13 Sarah F Hak, Roderick P Venekamp, Joanne G Wildenbeest, Louis J Bont
With interventions to prevent respiratory syncytial virus (RSV) infection within reach, this review aims to provide healthcare professionals with the latest information necessary to inform parents and assess the potential impact of RSV prevention on everyday practice. We address frequently asked questions for parental counseling.
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Delayed sleep wake phase disorder in adolescents: an updated review. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-12-07 Bhavya Narala, Muhammad Ahsan, Mathew Ednick, Catherine Kier
This review examines the most common circadian rhythm disorder in adolescents, delayed sleep phase disorder. It explores the etiology, prevalence, clinical features, diagnostic tools and criteria, and treatment options to identify sleep disorders early in the course. This is important to help improve youths in terms of education and quality of life.
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Management of hyperkalemia in children. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-11-27 Halima Janjua
Hyperkalemia is a potentially fatal electrolyte abnormality with no standardized management. The purpose of this review is to provide the knowledge needed for timely and effective management of hyperkalemia in children. It describes the utility of existing and novel therapies.
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Where a child lives matters: neighborhood deprivation and pediatric obesity. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-11-27 Chijioke Ikomi, Carissa M Baker-Smith
This article outlines what is currently known regarding the relationship between neighborhood deprivation and pediatric obesity. It discusses the intersectionality between neighborhood deprivation, race, ethnicity, and pediatric obesity. We conclude by proposing several potential solutions to disparities in pediatric obesity related to neighborhood deprivation.
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New primary immunodeficiencies 2023 update. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-11-27 Joyce E Yu
Primary immunodeficiency diseases (PIDs), also called inborn errors of immunity (IEI), are genetic disorders characterized by increased susceptibility to infection and/or aberrant regulation of immunological pathways. This review summarizes and highlights the new IEI disorders in the International Union of Immunological Societies (IUIS) 2022 report and current trends among new PIDs.
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Pigmented villonodular synovitis/giant cell tumor in the knee. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-11-24 Danielle E Chipman, Crystal A Perkins, Emilie Lijesen, Daniel W Green
Pigmented villonodular synovitis (PVNS) is a rare diagnosis in pediatric patients and commonly presents with symptoms of swelling and pain. Early diagnosis is important to prevent secondary degeneration into the subchondral bone. This review will analyze the etiology, clinical signs/symptoms, diagnosis, treatment, and recent literature on PVNS in the pediatric population.
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Early-onset scoliosis. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-11-23 Fernando Moreno Mateo, Patawut Bovonratwet, Alejandro Peiró García
The aim of this review is to provide the reader with the most updated available information so that it can be helpful in the approach of patients with early-onset scoliosis (EOS).
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Novel therapies for pediatric acute lymphoblastic leukemia. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-11-23 Zachary Graff, Michael J Burke, Nathan Gossai
This review summarizes the current novel therapy landscape in pediatric acute lymphoblastic leukemia (ALL), with a focus on key clinical trials which will shape the future direction of care for these children.
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School-based health: an area of opportunity to address challenges in management of pediatric obesity and type 2 diabetes. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-11-20 Aurelia C H Wood, Keeley Pratt
Obesity and type 2 diabetes (T2D) are increasingly common, chronic, and complex and disproportionally affect systemically under-resourced communities negatively impacted by social determinants of health. The primary goals of management for both conditions are improvement of medical and psychosocial well being and prevention of secondary complications. The advent of pediatric specific multidisciplinary
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Overview of modern genomic tools for diagnosis and precision therapy of childhood solid cancers. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-11-17 Elaine R Mardis
The application of technology and computational analyses to generate new data types from pediatric solid cancers is transforming diagnostic accuracy. This review provides an overview of such new capabilities in the pursuit of improved treatment for essentially rare and underserved diseases that are the highest cause of mortality in children over one year of age. Sophisticated ways of identifying therapeutic
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The potential role of social care in reducing childhood obesity. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-11-17 Evianna Cruz Herrera, Amanda I Figueroa-Nieves, Jennifer A Woo Baidal
This review evaluates the current evidence for relationships of social factors with childhood obesity and for a role of social care in reduction of childhood obesity.
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Narrative review: food as medicine across the pediatric age continuum. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-11-16 Laura Fischer, Hemen Muleta, Kofi Essel
Poor diet and food insecurity contribute to the dramatic rise in diet-related chronic disease and increasing cost of healthcare. The Food as Medicine (FAM) framework describes food-based interventions designed to prevent, manage, and treat diet-related diseases. However, FAM interventions have not been widely implemented or evaluated in pediatric populations, so critical questions remain about their
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Using the lens of trauma informed care to inform pediatric obesity management. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-11-16 Vanessa P Scott, Kyung E Rhee
Summarize the evolution of the trauma-informed care (TIC) approach in pediatrics, highlight the importance of using this lens in pediatric obesity management and treating the whole patient and family, and suggest recommendations for providers to incorporate TIC into their practice.
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Current status of weight bias and stigma in pediatrics and the need for greater focus on populations at risk. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-11-16 Stephanie W Waldrop, Daisy Wang, Devin Kancherla, Fatima Cody Stanford
Obesity is one of the most common pediatric chronic conditions in the United States, affecting approximately 20% of American youth and is more common amongst Black, Latino, and Indigenous and low socioeconomic populations. The condition places children and adolescents at increased risk of physical and mental health conditions partly mediated by the weight bias and stigmatization experienced during
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Fluid and electrolyte management in the neonate and what can go wrong. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-11-15 Jeffrey L Segar, Jennifer G Jetton
This review highlights recent advances in understanding fluid and electrolyte homeostasis during the newborn period, including heightened recognition of fluid overload and acute kidney injury contributing to poor clinical outcomes. Particular attention is given towards the care of extremely preterm infants.
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Recent advances in the treatment of childhood cancers. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-11-15 Timothy J D Ohlsen, Melissa R Martos, Douglas S Hawkins
Although cancer remains the leading nonaccidental cause of mortality in children, substantial advances in care have led to 5-year overall survival exceeding 85%. However, improvements in outcomes have not been uniform across malignancies or strata of social determinants of health. The current review highlights recent areas of advancement and anticipated directions for future progress.
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Assessing sleep behaviors in Latino children and adolescents: what is known, what are we missing, and how do we move forward? Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-11-08 Estela Blanco,Eric T Hyde,Suzanna M Martinez
PURPOSE OF THE REVIEW Sleep health is a commonly overlooked component of pediatric cardiometabolic risk. Disparities in sleep duration and meeting of pediatric sleep guidelines have been well documented among at-risk populations in the United States, including Latinos. However, sleep research often fails to describe or account for contextual and cultural factors impacting the ability for Latino families
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Hereditary causes of hypertension due to increased sodium transport. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-11-02 Jinwei Zhang
PURPOSE OF REVIEW Hypertension, commonly known as high blood pressure, is a widespread health condition affecting a large number of individuals across the globe. Although lifestyle choices and environmental factors are known to have a significant impact on its development, there is growing recognition of the influence of genetic factors in the pathogenesis of hypertension. This review specifically
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One academic medical center's experience in growing the genetic counseling service. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-11-02 Nathaniel H Robin,Taylor N McClinchey
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My radius is broken - do I need a cast or is a splint enough? Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-10-27 Daniella Ogilvie, Mariel Liebeskind, Shevaun M Doyle, Folorunsho Edobor-Osula
The treatment of many distal radius fractures has shifted from casting to splinting or the application of a soft dressing. This review includes a review of the types of pediatric distal radius fractures and the most recent literature on the management of these injuries.
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Traumatic injuries of the immature hip and pelvis. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-10-18 David Moore, Rose Gnap, Fergal Monsell
The pelvis and hip account for 0.3--4% of fractures of the immature skeleton, and generally result from high energy trauma. These fractures range in severity from apophyseal avulsions to complete disruptions of the pelvic ring. The purpose of this article is to review the presentation, diagnosis, treatment and complications of these injuries in order to inform clinicians involved in their management
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Bone health in children undergoing solid organ transplantation. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-10-10 Bianca Pinto, Radhika Muzumdar, Natalie Hecht Baldauff
Pediatric solid organ transplant recipients are a unique and growing patient population who are at risk for metabolic bone disease both before and after transplantation.
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Acute management of childhood stroke. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-10-07 Melissa G Chung, Lisa Pabst
The purpose of this paper is to review recent updates in the acute management of childhood arterial ischemic stroke, including reperfusion therapies and neuroprotective measures.
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Neuroimaging to guide neuroprognostication in the neonatal intensive care unit. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-10-07 Rhandi Christensen, Linda S de Vries, Mehmet N Cizmeci
Neurological problems are common in infants admitted to the neonatal intensive care unit (NICU). Various neuroimaging modalities are available for neonatal brain imaging and are selected based on presenting problem, timing and patient stability.
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Overgrowth syndromes, diagnosis and management. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-10-05 Steven D Klein, Alex Nisbet, Jennifer M Kalish
This review will focus on the current knowledge of the diagnosis and management of overgrowth syndromes with specific focus on mosaic conditions and treatment strategies.
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A practical approach to caring for atopic dermatitis in children. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-09-29 Diana K Bayer
PURPOSE OF REVIEW Atopic dermatitis is a chronic, systemic disease with primary cutaneous clinical manifestations and is commonly attributed to an exaggerated Th2 inflammatory response. Recent research regarding risk factors, prevention, clinical features, and management of atopic dermatitis will be reviewed. RECENT FINDINGS In the last decade, advances have been made in identifying the factors that
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Epidemiology, causes, and morbidities of stroke in the young. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-09-28 Anna M Janas,Megan Barry,Sarah Lee
PURPOSE OF REVIEW The purpose is to describe the latest research on epidemiology, causes, and morbidities of stroke in neonates and children. RECENT FINDINGS The global incidence of childhood stroke is approximately 2 per 100 000 person-years, which is significantly lower compared to neonates (20-40 per 100 000 live births) and adults (80-90 per 100 000 person-years). Placental abnormalities are a
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Progress in the field of hematopoietic stem cell-based therapies for inborn errors of immunity. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-09-21 Danielle E Arnold,Sung-Yun Pai
PURPOSE OF REVIEW Hematopoietic stem cell-based therapies, including allogeneic hematopoietic cell transplantation (HCT) and autologous gene therapy (GT), have been used as curative therapy for many inborn errors of immunity (IEI). As the number of genetically defined IEI and the use of HCT and GT increase, valuable data on outcomes and approaches for specific disorders are available. We review recent
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Newborn screening for severe combined immunodeficiency and inborn errors of immunity. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-09-14 Atar Lev,Raz Somech,Ido Somekh
PURPOSE OF REVIEW Severe combined immune deficiency (SCID) is the most devastating genetic disease of the immune system with an unfavorable outcome unless diagnosed early in life. Newborn screening (NBS) programs play a crucial role in facilitating early diagnoses and timely interventions for affected infants. RECENT FINDINGS SCID marked the pioneering inborn error of immunity (IEI) to undergo NBS
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Something to consider: rapid palatal expansion for treatment of obstructive sleep apnea in pediatric patients. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-09-08 Muhammad Ahsan, Bhavya Narala, Mathew Ednick, Catherine Kier
This review examines the potential of rapid palatal expansion (RPE) as a treatment for pediatric obstructive sleep apnea (OSA). The focus is on recent findings related to its efficacy, safety, patient selection, timing, appliance options, cost considerations, and long-term outcomes.
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Physical influences on the skin barrier and pathogenesis of allergy. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-09-01 Jessica W Hui-Beckman, Donald Y M Leung
As the incidence of allergic conditions has increased in recent decades, the effects of climate change have been implicated. There is also increased knowledge on the effects of other physical influences, such as scratching and Staphylococcus aureus. The skin barrier is the first line of defense to the external environment, so understanding the ways that these factors influence skin barrier dysfunction
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A new era in cystic fibrosis care: always changing and adapting. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-08-21 Barry L Diener, Fredy Huertero, Teresa Stables-Carney, Maureen Hoelzer, Catherine Kier
This review focuses on sharing the current and changing cystic fibrosis (CF) care model. This includes changes in CF care as a chronic disease with availability of new revolutionary, highly effective therapies as well as incorporation of shared decision-making, coproduction of care, quality improvement, telemedicine, and remote patient monitoring.
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Acute pancreatitis in children: risk factors, management, and outcomes. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-08-21 Megha S Mehta
Pediatric acute pancreatitis is an infrequent but potentially serious condition in children. Most have mild cases with spontaneous resolution, but up to one-third of patients can have moderate or severe disease or progress to recurrent or chronic pancreatitis.
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Unique clinical challenges for the teenager with congenital heart disease. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-08-08 Tony Pastor, Robert W Elder
On top of existing rites of passage, adolescents with congenital heart disease (CHD) face additional challenges as related to their underlying medical condition. These include compliance with medications and appointments, establishing heart-healthy behaviors, navigating potential at-risk situations, and transition to adult-oriented care.
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The common trisomy syndromes, their cardiac implications, and ethical considerations in care. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-08-08 Katherine A Kosiv, Mark R Mercurio, John C Carey
To review the incidence of congenital heart disease in the trisomies, highlight the history of cardiac surgery in trisomy 21 comparing it to the increase in cardiac surgery in trisomies 13 and 18, discuss ethical issues specific to trisomies 13 and 18, and suggest a pathway of shared decision-making in the management of congenital heart disease in trisomy 13 and 18, specifically congenital heart surgery
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Current opinion in pediatrics: what is new with irritable bowel syndrome. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-08-07 Hebat Y Kamal, Kayla Morneault-Gill, Christina B Chadwick
This review aims to summarize the most up-to-date criteria for diagnosis of pediatric irritable bowel syndrome (IBS) and treatment options. It also explores recent research that has been performed evaluating risk factors, pathophysiology, and treatment designed to improve quality of life for those who suffer from IBS. IBS is a common disorder in pediatrics and one of the most common causes of abdominal
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Recent advances in immunomodulators for atopic dermatitis. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-08-01 Hyun J Yim, Tiffany Jean, Peck Y Ong
Conventional treatments of atopic dermatitis have been inadequate, especially in patients with moderate-to-severe disease.
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Bicuspid aortic valve and its ascending aortopathy. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-07-27 Emma C Dunne, Ronald V Lacro, Jonathan N Flyer
To synthesize and critically assess recent clinical and research advancements in pediatric bicuspid aortic valve (BAV) and its associated aortopathy.
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Mechanical ventilation during pediatric extracorporeal life support. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-07-26 Martin C J Kneyber, Ira M Cheifetz
To discuss the role of ventilator induced lung injury (VILI) and patient self-inflicted lung injury in ventilated children supported on extracorporeal membrane oxygenation (ECMO).
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Nutritional and feeding challenges in aerodigestive patients. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-07-25 Charles B Chen
Aerodigestive disorders encompass conditions that affect both the airway and gastrointestinal tract. These include conditions such as acquired and congenital defects of the airway and esophagus as well as neuromuscular disorders. Patients often suffer from dysphagia, aspiration, and respiratory disorders. This article will provide a review of current practices in the management of feeding disorders
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Cardiac problems in the fetus: a review for pediatric providers. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-07-20 Erin A Paul, Jennifer Cohen, Miwa K Geiger
The aim of this study was to provide pediatric providers with a review of the diagnosis and management of fetal cardiac disease in the current era.
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Avoidant restrictive food intake disorder and pediatric feeding disorder: the pediatric gastroenterology perspective. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-07-18 Richard J Noel
Avoidant/restrictive food intake disorder (ARFID) and pediatric feeding disorder (PFD) are the newest evolutions of frameworks for dysfunctional feeding and share overlapping features but maintain notable differences. This review will compare the two frameworks, highlighting some of the latest advances in diagnosis and management.
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Updates in food allergen immunotherapy. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-07-10 Vibha Szafron, Ruchit Rana, Sara Anvari
Food allergies are on the rise. Though allergen avoidance and management of acute reactions have been the backbone of therapy, complete avoidance and timely acute care is often not feasible. Food allergen immunotherapy (FAIT) is a novel and evolving treatment option intended to induce desensitization and potential sustained unresponsiveness (SU) to food allergens. This review addresses the methods
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Advocacy: caring for teens beyond the bedside. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-08-01 Carly E Guss,Sarah Pitts
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Advances in cochlear gene therapies. Curr. Opin. Pediatr. (IF 3.6) Pub Date : 2023-07-07 Miles J Klimara, Richard J H Smith
Hearing loss is the most common sensory deficit and in young children sensorineural hearing loss is most frequently genetic in etiology. Hearing aids and cochlear implant do not restore normal hearing. There is significant research and commercial interest in directly addressing the root cause of hearing loss through gene therapies. This article provides an overview of major barriers to cochlear gene