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Characterisation and validation of lactation information from structured electronic health records for use in pharmacoepidemiological studies Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-03-17 Hibo H. Mohamed, Kirsten Ehresmann, Elisabeth M. Seburg, Gabriela Vazquez-Benitez, Ellen W. Demerath, David A. Fields, Kimberly K. Vesco, Elyse O. Kharbanda, Kristin Palmsten
Breastfeeding information stored within electronic health records (EHR) has recently been used for pharmacoepidemiological research, however the data are primarily collected for clinical care.
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Cardiovascular mortality in the context of hypertensive disorders of pregnancy: Towards an optimisation of case identification strategies Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-03-10 Isabelle Malhamé, Sonia M. Grandi
Cardiovascular conditions have become the leading cause of maternal mortality in high-income settings.1 Hypertensive disorders of pregnancy (HDP), occurring in 10% of pregnancies worldwide, remain major contributors to pregnancy-related cardiovascular morbidity.1, 2 Thus, a better understanding of the contribution of HDP to pregnancy-related cardiovascular complications is critical to reducing the
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Harnessing women's full reproductive history in assessing cardiovascular risk Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-03-08 Rolv Skjaerven, Liv G. Kvalvik
In 1935 Leon Chesley1 initiated a follow-up of a small cohort of women who experienced eclampsia to try to find the answer to the question of whether eclampsia causes vascular damage, eventually culminating in CVD in women. Close to a century later, we are still struggling to understand the link between hypertensive disorders of pregnancy (HDP) and later cardiovascular health. In this special issue
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Cohort profile: The Copenhagen Analgesic Study—The COPANA cohort Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-03-08 Margit Bistrup Fischer, Gylli Mola, Lone Scheel, Katrine Bak Wraae, Ane Lilleøre Rom, Hanne Frederiksen, Trine Holm Johannsen, Kristian Almstrup, Karin Sundberg, Hanne Kristine Hegaard, Anders Juul, Casper P. Hagen
BackgroundDevelopment of the gonads during fetal life is complex and vital for adult reproductive health. Cell and animal studies have shown an alarming effect of mild analgesics on germ cells in both males and females. More than 50% of pregnant women use mild analgesics during pregnancy, which potentially could compromise the reproductive health of the next generation.ObjectivesWe present a research
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Cohort profile: The Assessing Imperial Valley Respiratory Health and the Environment (AIRE) study Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-03-07 Shohreh F. Farzan, Elizabeth Kamai, Dayane Duenas Barahona, Yoshira Van Horne Ornelas, Christopher Zuidema, Michelle Wong, Christian Torres, Esther Bejarano, Edmund Seto, Paul English, Luis Olmedo, Jill Johnston
BackgroundThe Children's Assessing Imperial Valley Respiratory Health and the Environment (AIRE) study is a prospective cohort study of environmental influences on respiratory health in a rural, southeastern region of California (CA), which aims to longitudinally examine the contribution of a drying saline lake to adverse health impacts in children.ObjectivesThis cohort was established through a community–academic
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Common risk factors in the shadow of rare pregnancy complications: Spotlighting the role of cardiovascular health in placental abruption Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-03-07 Natalie A. Cameron, Sadiya S. Khan
Adverse pregnancy outcomes (APOs) are often conceptualised as a window into future cardiovascular disease (CVD) risk. The available evidence for commonly occurring APOs such as hypertensive disorders of pregnancy, gestational diabetes and preterm birth suggest a two-fold higher risk of CVD following these APOs in the birthing adult.1, 2 In addition, APOs are associated with a higher risk of development
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Hypertensive disorders across successive pregnancies and cardiovascular risks: A nuanced picture emerges, but raises questions too Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-03-01 Cande V. Ananth, Justin S. Brandt
The cardiovascular system undergoes dramatic adaptations in pregnancy.1 The heart rate increases in the first trimester. By the third trimester, the heart rate may be 10–15 beats per minute faster, often resulting in a physiologic resting tachycardia. The blood volume nearly doubles, expanding and then plateauing between 28 and 32 weeks' gestation. This expansion is even more dramatic in twins and
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Multiple mediators, causal assumptions and potential caveats Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-02-29 Jeffrey N. Bone, Cande V. Ananth
In recent years there has been rapid advancement in the available methods for effect decomposition through mediation analysis and clarification of the assumptions required for the interpretation of the estimated mediation effects.1 This is largely due to a mathematical formalisation of mediation analysis through the counterfactual framework for causal inference. In this issue of Pediatric and Perinatal
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Studies of recurrent outcomes in perinatal epidemiology: To describe, explain or predict? Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-02-28 Jonathan M. Snowden, Jennifer A. Hutcheon
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Is it time to re‐think how we look for teratogenic effects in exposure cohort studies? Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-02-27 Jan M. Friedman
In this issue of Paediatric and Perinatal Epidemiology, Segovia Chacón and her associates1 used linked data on 1,100,000 live births from the Swedish Birth Defects and Health Registries to ask whether estimates of the prevalence of major congenital anomalies differ by age of the child, a question that colours how we interpret birth defect rates observed in exposure cohort studies. The authors found
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Vascular health after assisted reproduction: A stroke of bad luck? Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-02-27 Natalie Dayan, Jacob A. Udell
Since the first published case report of a successful in vitro fertilisation (IVF) pregnancy in 1978,1 the use of assisted reproductive technologies (ART) has markedly increased, accounting for 1% of births in Canada, and rising.2 These procedures have allowed couples struggling with infertility, single-birthing parents and same-sex couples to realise their dreams of procreation. ART often involves
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Pregnancy, stroke and selection bias Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-02-22 Sarit Kang‐Auger, Émilie Brousseau, Shu Qin Wei
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Heterogeneity in the risk of cardiovascular disease mortality after the hypertensive disorders of pregnancy across mothers' lifetime reproductive history Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-02-21 Sage Wyatt, Liv Grimstvedt Kvalvik, Aditi Singh, Kari Klungsøyr, Truls Østbye, Rolv Skjærven
BackgroundPrior studies on maternal cardiovascular disease (CVD) mortality and hypertensive disorders of pregnancy (HDP) have focused only on a woman's first birth and have not accounted for successive affected pregnancies.ObjectivesThe objective of this study is to identify mothers' risk of CVD mortality considering lifetime reproductive history.MethodsWe used data from the Medical Birth Registry
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Pregnancy‐associated mortality due to cardiovascular disease: Impact of hypertensive disorders of pregnancy Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-02-20 Rachel Lee, Justin S. Brandt, K. S. Joseph, Cande V. Ananth
BackgroundReported rates of maternal mortality in the United States have been staggeringly high and increasing, and cardiovascular disease (CVD) is a chief contributor to such deaths. However, the impact of hypertensive disorders of pregnancy (HDP) on the short‐term risk of cardiovascular death is not well understood.ObjectivesTo evaluate the association between HDP (chronic hypertension, gestational
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Temporal changes in pre-existing health conditions five years prior to pregnancy in British Columbia, Canada, 2000–2019 Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-02-17 Louise Lundborg, K. S. Joseph, Sarka Lisonkova, Wee-Shian Chan, Qi Wen, Cande V. Ananth, Neda Razaz
Pre-existing health conditions increase the risk of obstetric complications during pregnancy and birth. However, the prevalence and recent changes in the frequency of pre-existing health conditions in the childbearing population remain unknown.
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Inequalities in access to prenatal care during the COVID-19 pandemic: Analysis of a population-based cohort Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-02-10 Erin Hetherington, Elizabeth Darling, Sam Harper, Francis Nguyen, Laura Schummers, Wendy V. Norman
Before the COVID-19 pandemic, access to prenatal care was lower among some socio-demographic groups. This pandemic caused disruptions to routine preventative care, which could have increased inequalities.
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Cumulative maternal exposures of inflammation and attention-deficit, hyperactivity disorder risk in children: Does one size fit all? Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-02-08 Neda Razaz, Cande V. Ananth
Attention-Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder involving impaired attention, hyperactivity and impulsive behaviour; the condition affects over 3% of children worldwide.1 ADHD not only poses potential life-threatening risks for individuals but also exerts a significant economic burden on society—estimated to cost $31.6 billion annually in the United States.2 Identifying
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Academic achievement at ages 11 and 16 in children born with congenital anomalies in England: A multi-registry linked cohort study Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-02-06 Svetlana V. Glinianaia, Joachim Tan, Joan K. Morris, Jo Brigden, Hannah E. R. Evans, Maria Loane, Amanda J. Neville, Judith Rankin
Children born with major congenital anomalies (CAs) have lower academic achievement compared with their peers, but the existing evidence is restricted to a number of specific CAs.
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Placental Abruption and Cardiovascular Event Risk (PACER): Design, data linkage, and preliminary findings Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-01-26 Cande V. Ananth, Rachel Lee, Linda Valeri, Zev Ross, Hillary L. Graham, Shama P. Khan, Javier Cabrera, Todd Rosen, William J. Kostis
Obstetrical complications impact the health of mothers and offspring along the life course, resulting in an increased burden of chronic diseases. One specific complication is abruption, a life-threatening condition with consequences for cardiovascular health that remains poorly studied.
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Maternal neighbourhood-level social determinants of health and their association with paediatric hepatitis C screening among children exposed to hepatitis C in pregnancy Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-01-26 Mary K. Foley, Maya Djerboua, Tatyana Kushner, Mia J. Biondi, Jordan J. Feld, Norah A. Terrault, Jennifer A. Flemming
Current guidelines recommend HCV screening by 18 months of age for those exposed to HCV in utero; yet, screening occurs in the minority of children.
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How are socioeconomic inequalities in preterm birth explained by maternal smoking and maternal body mass index: A mediation analysis Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-01-21 Philip McHale, Daniela K. Schlüter, Mark Turner, Angharad Care, Ben Barr, Shantini Paranjothy, David Taylor-Robinson
Preterm birth affects between 7% and 8% of births in the UK and is a leading cause of infant mortality and childhood disability. Prevalence of preterm birth has been shown to have significant and consistent socioeconomic inequalities.
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Assessing cardiovascular disease risk in women with a history of hypertensive disorders of pregnancy: A guidance paper for studies using administrative data Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-01-14 Amy Johnston, Graeme N. Smith, Peter Tanuseputro, Thais Coutinho, Jodi D. Edwards
Hypertensive disorders of pregnancy (HDP) are a major cause of maternal morbidity and mortality, and their association with increased cardiovascular disease (CVD) risk represents a major public health concern. However, assessing CVD risk in women with a history of these conditions presents unique challenges, especially when studies are carried out using routinely collected data.
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Estimating the effect of diuretics and inhaled corticosteroids for evolving bronchopulmonary dysplasia in preterm infants Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-01-08 Jonathan L. Slaughter, Mark A. Klebanoff, Erinn M. Hade
Off-label treatment of extremely preterm infants with diuretics and inhaled corticosteroids (ICS) for evolving bronchopulmonary dysplasia (BPD) is common. Their effectiveness in reducing mortality or BPD severity, and optimal treatment timing, are unclear.
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Better understanding of discharge against medical advice for the improvement of health among Australian Aboriginal children Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-01-10 Judith M. Katzenellenbogen, Melanie Robinson, Ingrid Stacey
Aboriginal and Torres Strait Islander (hereafter, respectfully Aboriginal) people, the First Nations peoples of Australia, comprise 3.8% of the total Australian population.1 Aboriginal Australians live in varying geographical contexts and are culturally, linguistically and socio-economically diverse, contributing richly to Australian life. The health of Aboriginal children is a priority for Aboriginal
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Studying reproductive and gynaecologic health as risk factors for chronic disease development Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-01-07 Leslie V. Farland, Anna Z. Pollack, Karen C. Schliep
CONFLICT OF INTEREST STATEMENT The authors declare that they have no competing interests.
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Spatial–temporal distribution of preterm birth in China, 1990–2020: A systematic review and modelling analysis Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2024-01-02 Wei-Hua Hu, Xin-Yuan Gao, Xiu-Xiu Li, Qing-Mei Lin, Li-Ping He, Ying-Si Lai, Yuan-Tao Hao
Little is known about the long-term trends of preterm birth rates in China and their geographic variation by province.
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Risk of stroke the year following a delivery after using assisted reproductive technologies Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-12-29 Maria C. Magnus, Siri E. Håberg, Kristiina Rönö, Liv Bente Romundstad, Christina Bergh, Anne Lærke Spangmose, Anja Pinborg, Mika Gissler, Ulla-Britt Wennerholm, Signe Opdahl
Studies indicate that individuals who deliver after assisted reproductive technologies (ART) may have an increased risk of cardiovascular disease (CVD). A recent large study from the U.S. showed a higher risk of stroke during the first year after delivery.
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Insights from the epidemiology of cerebral palsy: Navigating the advantages and limitations of registry versus administrative health data Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-12-27 Sandra Julsen Hollung, Joanne Given
Epidemiological research provides insights into risk factors, prevalence and outcomes of cerebral palsy (CP), a lifelong motor disorder. It provides a foundation to monitor trends and evaluate the effectiveness of interventions and public health policy. There are different approaches to gathering these insights, including the use of population-based registries, administrative health databases and insurance
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Maternal body mass index and cerebral palsy in children: A systematic review and dose–response meta-analysis Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-12-26 Guomin Hu, Yang Zhao, Xueru Fu, Dongsheng Hu, Xin Liang
Accumulating studies indicate that maternal obesity is associated with the risk of cerebral palsy (CP); however, their conclusions have been inconsistent.
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Structural racism, nativity and risk of adverse perinatal outcomes among Black women Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-12-20 Safyer McKenzie-Sampson, Rebecca J. Baer, Laura L. Jelliffe-Pawlowski, Deborah Karasek, Corinne A. Riddell, Jacqueline M. Torres, Bridgette E. Blebu
Black women in the United States (US) have the highest risk of preterm birth (PTB) and small for gestational age (SGA) births, compared to women of other racial groups. Among Black women, there are disparities by nativity whereby foreign-born women have a lower risk of PTB and SGA compared to US-born women. Differential exposure to racism may confer nativity-based differences in adverse perinatal outcomes
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Complexities of studying fertility across the reproductive life course Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-12-20 Martha M. Werler
CONFLICT OF INTEREST STATEMENT The author has no conflict of interest.
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Cannabis use in the preconception period: Does it increase the risk of gestational diabetes? Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-12-20 Kartik K. Venkatesh, Sarah A. Keim
Rising preconception and prenatal cannabis use in the United States is a growing public health issue.1 Between 2002 and 2021, cannabis use in pregnancy doubled from 3.4% to 7.2% of pregnant individuals, albeit higher in the first trimester than in later trimesters.2, 3 During the COVID-19 pandemic, nearly 25% of pregnant individuals in some parts of the United States reported cannabis use.1 These changing
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Association of maternal cancer with congenital anomalies in offspring Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-12-19 Nathalie Auger, Amanda Maniraho, Aimina Ayoub, Laura Arbour
Congenital anomalies are common, but the possibility that maternal cancer increases the chance of having a child with a birth defect is not fully understood.
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Bias analyses to investigate the impact of differential participation: Application to a birth defects case-control study Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-12-15 Julie M. Petersen, Jacob C. Kahrs, Nedghie Adrien, Mollie E. Wood, Andrew F. Olshan, Louisa H. Smith, Meredith M. Howley, Elizabeth C. Ailes, Paul A. Romitti, Amy H. Herring, Samantha E. Parker, Gary M. Shaw, Maria D. Politis
Certain associations observed in the National Birth Defects Prevention Study (NBDPS) contrasted with other research or were from areas with mixed findings, including no decrease in odds of spina bifida with periconceptional folic acid supplementation, moderately increased cleft palate odds with ondansetron use and reduced hypospadias odds with maternal smoking.
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Unveiling sex bias and adverse neonatal outcomes in ultrasound estimation of gestational age: A population-based cohort study Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-12-12 Anders Einum, Linn Marie Sørbye, Roy Miodini Nilsen, Cathrine Ebbing, Nils-Halvdan Morken
Gestational age estimation by second-trimester ultrasound biometry introduces systematic errors due to sex differences in early foetal growth, consequently increasing the risk of adverse neonatal outcomes. Ultrasound estimation earlier in pregnancy may reduce this bias.
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Point: Abnormalities of foetal growth—Is it time to move towards a personalised medicine approach to predict adverse neonatal outcomes? Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-12-11 Katherine L. Grantz, Jun Zhang
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest.
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Maternal obesity and childhood asthma risk: Exploring mediating pathways Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-12-06 Natalie A. Rosenquist, Megan Richards, Jeannette R. Ferber, Matthew J. Strickland, So Young Ryu, Heather Burkin, Ann M. Weber, De-Kun Li, Lyndsey A. Darrow
Growing evidence for the effect of maternal obesity on childhood asthma motivates investigation of mediating pathways.
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Using mothers as the denominator Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-12-04 Katherine A. Ahrens
CONFLICT OF INTEREST STATEMENT The author has no conflict of interest.
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Association between cumulative maternal exposures related to inflammation and child attention-deficit/hyperactivity disorder: A cohort study Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-11-27 Timothy C. Nielsen, Natasha Nassar, Antonia W. Shand, Hannah F. Jones, Velda X. Han, Shrujna Patel, Adam J. Guastella, Russell C. Dale, Samantha J. Lain
Preclinical studies suggest synergistic effects of maternal inflammatory exposures on offspring neurodevelopment, but human studies have been limited.
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A comparison of cohorts of children with cerebral palsy from a population register and hospital admission data: A data linkage study Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-11-30 Simon P. Paget, Sarah McIntyre, Samantha Lain, Shona Goldsmith, Natasha Nassar
Administrative health data, such as hospital admission data, are often used in research to identify children/young people with cerebral palsy (CP).
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Counterpoint: Are abnormal fetal growth indices valid predictors of neonatal morbidity and mortality? Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-11-27 Sid John, K. S. Joseph, John Fahey, Shiliang Liu, Michael S. Kramer
Hocquette and Zeitlin1 and Grantz and Zhang2 highlight a few issues with regard to our paper3 on the performance of birthweight-for-gestational age charts and birthweight centiles at term gestation. In this counterpoint, we discuss the points raised, including the choice of outcome for evaluating birthweight-for-gestational age charts, the potential impact of obstetrical intervention(s) on such assessments
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Hospital and emergency department discharge against medical advice in Western Australian Aboriginal children aged 0–4 years from 2002 to 2018: A cohort study Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-11-20 Daniel Christensen, Alison Gibberd, Bridgette McNamara, Sandra Eades, Carrington Shepherd, David B. Preen, Daniel McAullay, Natalie Strobel
Discharge against medical advice (DAMA) is a priority issue for the health system. Little is known about the factors associated with DAMA for Aboriginal and/or Torres Strait Islander (Aboriginal) children in Australia.
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History of multifetal gestation and long-term maternal mortality Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-11-15 Susanna D. Mitro, Rajeshwari Sundaram, Yan Qiao, Jessica L. Gleason, Edwina Yeung, Stefanie N. Hinkle, Pauline Mendola, James L. Mills, Sonia M. Grandi, Sunni L. Mumford, Enrique F. Schisterman, Cuilin Zhang, Katherine L. Grantz
Multifetal gestation could be associated with higher long-term maternal mortality because it increases the risk of pregnancy complications such as preeclampsia and preterm birth, which are in turn linked to postpartum cardiovascular risk.
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A prediction model for classifying maternal pregnancy smoking using California state birth certificate information Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-11-15 Di He, Xiwen Huang, Onyebuchi A. Arah, Douglas I. Walker, Dean P. Jones, Beate Ritz, Julia E. Heck
Systematically recorded smoking data are not always available in vital statistics records, and even when available it can underestimate true smoking rates.
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Point: Setting realistic expectations for the evaluation of intrauterine growth charts Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-11-03 Alice Hocquette, Jennifer Zeitlin
The question of which growth chart should be used for identifying fetuses and newborns at risk because of suboptimal growth was propelled into the scientific arena by the INTERGROWTH 21st and World Health Organization (WHO) projects to develop intrauterine growth standards (i.e. charts developed in low-risk populations with normal growth) in the mid-2010s.1, 2 Previously, despite broad consensus in
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Levothyroxine initiation and the risk of pregnancy loss among pregnant women with subclinical hypothyroidism: An observational study emulating a target trial Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-11-03 Sonia M. Grandi, Ya-Hui Yu, Pauline Reynier, Robert W. Platt, Oriana H. Y. Yu, Kristian B. Filion
While the benefits of levothyroxine are well-established for overt hypothyroidism, they are unclear for subclinical hypothyroidism (SCH) among pregnant women.
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Cohort profile update: The Canadian Maternal–Infant Research on Environmental Chemicals Child Development study (MIREC-CD PLUS) Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-11-03 Mandy Fisher, Gina Muckle, Bruce Lanphear, Tye E. Arbuckle, Joseph M. Braun, Angelika Zidek, Maria P. Vélez, Nicole Lupien, Stephanie Bastien, Jillian Ashley-Martin, Youssef Oulhote, Michael M. Borghese, Mark Walker, Elizabeth Asztalos, Maryse F. Bouchard, Linda Booij, Mark R. Palmert, Katherine M. Morrison, Elizabeth A. Cummings, Karine Khatchadourian, Constadina Panagiotopoulos, Gord Glendon, Robin
The pan-Canadian Maternal–Infant Research on Environmental Chemicals (MIREC) study was established to determine whether maternal environmental chemical exposures were associated with adverse pregnancy outcomes in 2001 pregnant women.
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Prevalence and correlates of very rapid repeat pregnancy: Pregnancy Risk Assessment Monitoring System, United States, 2009–2020 Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-10-23 Amanda Luff, Michelle Menegay, Maria F. Gallo
Most rapid repeat pregnancies, defined as those occurring within 18 months of a previous birth, are unintended. These pregnancies are associated with later initiation of prenatal care and are more common among people with lower socio-economic status and among racially and ethnically minoritised populations.
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Patterns of multiple chronic conditions in pregnancy: Population-based study using latent class analysis Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-10-21 Hilary K. Brown, Kinwah Fung, Eyal Cohen, Cindy-Lee Dennis, Sonia M. Grandi, Laura C. Rosella, Catherine Varner, Simone N. Vigod, Walter P. Wodchis, Joel G. Ray
Adults with multiple chronic conditions (MCC) are a heterogeneous population with elevated risk of future adverse health outcomes. Yet, despite the increasing prevalence of MCC globally, data about MCC in pregnancy are scarce.
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Type of infertility and prevalence of congenital malformations Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-10-20 Olga Basso, Gabriel D. Shapiro, Robert Gagnon, Robyn Tamblyn, Robert W. Platt
Children conceived with assisted reproductive technologies (ART) or after a long waiting time have a higher prevalence of congenital malformations, but few studies have examined the contribution of type of infertility.
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Detection of major congenital malformations depends on length of follow-up in Swedish National Health Register Data: Implications for pharmacoepidemiological research on medication safety in pregnancy Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-10-11 Silvia Segovia Chacón, Pär Karlsson, Carolyn E. Cesta
In observational medication pregnancy safety studies, children are often followed from birth to 1 year of age. However, some major congenital malformations (MCM) may take longer to diagnose.
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Risk factors for mortality in infancy and childhood in children with major congenital anomalies: A European population-based cohort study Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-10-10 Joachim Tan, Svetlana V. Glinianaia, Judith Rankin, Anna Pierini, Michele Santoro, Alessio Coi, Ester Garne, Maria Loane, Joanne E. Given, Joanna Brigden, Elisa Ballardini, Clara Cavero-Carbonell, Hermien E. K. de Walle, Laura García-Villodre, Miriam Gatt, Mika Gissler, Anna Heino, Sue Jordan, Babak Khoshnood, Kari Klungsoyr, Nathalie Lelong, Renée L. Lutke, Amanda J. Neville, David Tucker, Stine K
Preterm birth and young maternal age are known risk factors for infant and childhood mortality. There is limited knowledge of the impact of these risk factors in children born with major congenital anomalies (CAs), who have inherently higher risks of death compared with other children.
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The association between preconception cannabis use and gestational diabetes mellitus: The Preconception Period Analysis of Risks and Exposures Influencing health and Development (PrePARED) consortium Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-09-26 Ke Pan, Anne Marie Jukic, Gita D. Mishra, Sunni L. Mumford, Lauren A. Wise, Enrique F. Schisterman, Sylvia H. Ley, Brittany M. Charlton, Jorge E. Chavarro, Jaime E. Hart, Stephen Sidney, Xu Xiong, Celestina Barbosa-Leiker, Karen C. Schliep, Jeffrey G. Shaffer, Lydia A. Bazzano, Emily W. Harville
The metabolic changes that ultimately lead to gestational diabetes mellitus (GDM) likely begin before pregnancy. Cannabis use might increase the risk of GDM by increasing appetite or promoting fat deposition and adipogenesis.
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Preterm birth: An important risk factor for pulmonary hypertension Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-09-27 Kara N. Goss
CONFLICT OF INTEREST None.
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Validation of parental recall questionnaire to classify preterm delivery subtypes: Spontaneous preterm labour, preterm premature rupture of membranes and clinician-initiated preterm delivery Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-09-28 Janet W. Rich-Edwards, Jennifer J. Stuart, Iris A. Becene, Louise F. Largier, Kathryn M. Rexrode, David E. Cantonwine, Maribel O. Carpenter, Thomas F. McElrath, Kathryn J. Gray
Preterm delivery (PTD) includes three main presenting subtypes: spontaneous preterm labour (sPTL), preterm premature rupture of membranes (pPROM) and clinician-initiated preterm delivery (ciPTD). PTD subtype data are rarely available from birth registries and are onerous to derive from medical records.
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Children's satisfaction with a comprehensive study program—Results from the LIFE Child cohort study Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-09-25 Elisabeth Bier, Mandy Vogel, Nico Grafe, Anne Jurkutat, Juliane Ludwig, Oleg Wagner, Christof Meigen, Wieland Kiess, Tanja Poulain
Research participants' satisfaction is a topic of great interest, especially in the context of longitudinal studies. Evaluation also represents an important component of quality management in the health care system. Adult studies found that personal characteristics, e.g., age, sex, ethnicity, and SES, can influence satisfaction with health care or study participation. Studies on paediatric participants
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Paternal and maternal birthweight and offspring risk of macrosomia at term gestations: A nationwide population study Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-09-02 Svein Rasmussen, Ellen Øen Carlsen, Lorentz Erland Linde, Nils-Halvdan Morken, Siri Eldevik Håberg, Cathrine Ebbing
There is a paucity of data on whether parents' macrosomia (birthweight ≥4500 g) status influences the risk of macrosomia in the offspring. The role of maternal overweight in the generational effect of macrosomia is not known.
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The association between multidimensional sleep health and gestational weight gain Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-08-28 Marquis S. Hawkins, Darya Y. Pokutnaya, Lisa M. Bodnar, Michele D. Levine, Daniel J. Buysse, Esa M. Davis, Meredith L. Wallace, Phyllis C. Zee, William A. Grobman, Kathryn J. Reid, Francesca L. Facco
Although poor sleep health is associated with weight gain and obesity in the non-pregnant population, research on the impact of sleep health on weight change among pregnant people using a multidimensional sleep health framework is needed.
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Accuracy of aspirin prophylaxis for preeclampsia prevention documentation within a large administrative dataset Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-08-16 Lauren S. Tailor, Renee G. Fajardo, Joel G. Ray, Isabelle Malhamé, Sonia M. Grandi
Low-dose aspirin prophylaxis is recommended for women at risk of preeclampsia. Capturing aspirin prophylaxis within administrative databases can be challenging since it is an over-the-counter medication. The Better Outcome Registry and Network (BORN) database, a perinatal health registry in Ontario, Canada, includes a formal variable that captures aspirin prophylaxis for preeclampsia. This variable
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Association between vaginal bleeding in pregnancy that resulted in delivery and risk of cancer: A Danish registry-based cohort study Paediatric Perinat. Epidemiol. (IF 2.8) Pub Date : 2023-08-14 Elena Dudukina, Erzsébet Horváth-Puhó, Henrik Toft Sørensen, Vera Ehrenstein
Vaginal bleeding (VB) before 20 gestational weeks of a viable pregnancy is a manifestation of a threatened miscarriage. VB is associated with increased levels of pro-inflammatory cytokines such as interferon-gamma, tumour necrosis factor-alpha and interleukin-6. Increased levels of these cytokines and oxidative stress are risk factors for cancer. The risk of cancer following a VB-affected pregnancy