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Prospective evaluation of acute neurological events after paediatric cardiac surgery Cardiol. Young (IF 1.0) Pub Date : 2024-03-14 Olivia Frost, Deborah Ridout, Warren Rodrigues, Paul Wellman, Jane Cassidy, Victor T. Tsang, Dan Dorobantu, Serban C. Stoica, Aparna Hoskote, Katherine L. Brown
Objectives: Children with CHD are at heightened risk of neurodevelopmental problems; however, the contribution of acute neurological events specifically linked to the perioperative period is unclear. Aims: This secondary analysis aimed to quantify the incidence of acute neurological events in a UK paediatric cardiac surgery population, identify risk factors, and assess how acute neurological events
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Successful ductal stent implantation for initial palliation in two patients with aortic atresia and interrupted aortic arch Cardiol. Young (IF 1.0) Pub Date : 2024-03-13 Ensar Duras, Hacer Kamali, Selman Gokalp, Aysel Turkvatan, Alper Guzeltas
The coexistence of aortic valve atresia and interrupted aortic arch are an extremely rare condition. In this pathology, blood flow to the ascending aorta and coronary arteries should be provided through the ductus arteriosus or collaterals originating from the descending aorta. In rare cases where bilateral ductus arteriosus is present, they can provide circulation. Here, we report two cases in which
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Effect of Yangxin Huoxue Jiedu recipe on inflammatory factors and oxidative stress on viral myocarditis in children Cardiol. Young (IF 1.0) Pub Date : 2024-03-12 Hengrui Hao, Meixia Ji, Kuilong Zhou, Yunxia Zhang, Gaoyin Zhang, Lianying Ruan
Objective: This observation purposed to investigate the effect of the Yangxin Huoxue Jiedu formula on children with viral myocarditis and its effect on inflammatory factors and oxidative response. Materials and methods: A total of 121 children with viral myocarditis were randomly divided into two groups, namely the control group (N = 60) and the traditional Chinese medicine group (N = 61). The control
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Estimation of the inferior caval vein saturation using high-fidelity non-invasive haemodynamic values and validation of modelled estimates Cardiol. Young (IF 1.0) Pub Date : 2024-03-12 Rohit S. Loomba, Saul Flores, Juan S. Farias, Enrique G. Villarreal, Alex Constas
Objectives: Monitoring venous saturation allows identification of inadequate systemic oxygen delivery. The aim was to develop a model using non-invasive haemodynamic variables to estimate the inferior caval vein saturation and to determine its prognostic utility. Methods: This is a single-centre, retrospective study. A Bayesian Pearson’s correlation was conducted to model the inferior caval vein saturation
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Electrocardiographic proarrhythmic changes in pregnancy of women with CHD Cardiol. Young (IF 1.0) Pub Date : 2024-03-11 Constance G. Weismann, Frida Wedlund, Thuva Lindblad Ryd, Emma von Wowern, Joanna Hlebowicz
Objectives: Pregnancy-related physiological adaptations result in increased heart rate as well as electrocardiographic changes such as a mean QTc prolongation of 27 ms. Pregnant women with CHD are at increased risk for cardiovascular complications. The aim of this study was to identify risk factors for abnormally prolonged QTc interval—a risk factor for ventricular arrhythmias—in pregnant women with
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The role of lncRNAKCNQ1OT1/miR-301b/Tcf7 axis in cardiac hypertrophy Cardiol. Young (IF 1.0) Pub Date : 2024-03-08 Mingyao E, Feifei Ren, Yanhua Yu, Haiyan Li, Chao Shen
Objective: Cardiac hypertrophy, acting as a pathologic process of chronic hypertension and coronary disease, and its underlying mechanisms still need to be explored. Long non-coding RNA (LncRNA) potassium voltage-gated channel subfamily Q member 1 Transcript 1 (KCNQ1OT1) has been implicated in myocardial infarction. However, its role in cardiac hypertrophy remains reported. Method: To explore the regulated
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Sequence variations in GATA4 and CITED2 gene among patients with cardiac septation defects from Xinjiang, China Cardiol. Young (IF 1.0) Pub Date : 2024-03-08 Renati Imam, Maimaitiaili Aizezi, Fei Yan, Tao Zhu, Weimin Zhang
Studies have shown that genetic factors play an important role in CHD’s development. The mutations in GATA4 and CITED2 genes result in the failure of the heart to develop normally, thereby leading to septal defects. The present study investigated the underlying molecular aetiology of patients with cardiac septation defects from Xinjiang. We investigated variants of the GATA4 and CITED2 gene coding
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Analysis of haemodynamics surrounding blood transfusions after the arterial switch operation: a pilot study utilising real-time telemetry high-frequency data capture Cardiol. Young (IF 1.0) Pub Date : 2024-03-07 Matthew F. Mikulski, Antonio Linero, Daniel Stromberg, Jeremy T. Affolter, Charles D. Fraser, Carlos M. Mery, Richard P. Lion
Background: Packed red blood cell transfusions occur frequently after congenital heart surgery to augment haemodynamics, with limited understanding of efficacy. The goal of this study was to analyse the hemodynamic response to packed red blood cell transfusions in a single cohort, as “proof-of-concept” utilising high-frequency data capture of real-time telemetry monitoring. Methods: Retrospective review
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Care burden and support needs of caregivers of infants and children with CHDs and dysphagia Cardiol. Young (IF 1.0) Pub Date : 2024-03-07 Vivienne Norman, Liesl Zühlke, Brenda Morrow
Dysphagia is common in children with CHDs, resulting in multiple stressors for their caregivers including having a child with a serious medical condition and coping with their child’s feeding needs. However, relatively little is known about caregivers’ perceptions and experiences of the burden of care and support needs for their child with a CHD and dysphagia in low-middle income contexts. This qualitative
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Evaluation of handgrip strength in children with pulmonary hypertension Cardiol. Young (IF 1.0) Pub Date : 2024-03-07 Akif Kavgacı, Serdar Kula, Elif Berber Maraşlı, Murat Zinnuroğlu, Bülent Çelik, Semiha Terlemez, Sedef Tunaoğlu, Deniz Oğuz
Background: Handgrip strength is a crucial indicator of upper extremity muscular strength and is vital for monitoring disorders like cardiac diseases that restrict a patient’s physical activity and result in muscle atrophy. The aim of our study was to evaluate whether muscle strength loss is present in patients with pulmonary hypertension and whether this test can be an alternative to 6-minute walk
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Lower bone strength in young patients with Fontan circulation compared to controls Cardiol. Young (IF 1.0) Pub Date : 2024-03-07 Anna Wikner, Karna Johansson, Elin Enocson, Magne Sthen Bergdahl, Lena Hansson, Annika Rydberg, Camilla Sandberg
Objectives: Previous reports indicate bone deficits in patients with Fontan circulation. However, the consequences of these deficits on bone strength and when these changes occur are unclear. Aim: To compare the tibial bone strength-strain index between young patients (6–19 years) with Fontan circulation and age- and sex-matched controls, and to determine strength-strain-index in subgroups of children
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Creating a flow restrictor in ductal stenting: a novel technique Cardiol. Young (IF 1.0) Pub Date : 2024-03-06 Tam T. Doan, Yen T. K. Nguyen, T. C. B. Phung
Ductal stenting has transformed the care of neonates with ductal-dependent critical CHD, especially in low-income countries. In small infants, a 3.5- or 4-mm stent may lead to too much pulmonary blood flow resulting in pulmonary oedema. We herein presented a novel technique to restrict ductal stent flow in a premature neonate with pulmonary atresia and intact ventricular septum following radiofrequency
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Leukotriene B4 levels in CHD-associated paediatric pulmonary hypertension Cardiol. Young (IF 1.0) Pub Date : 2024-03-06 Gamze Vuran, Murat Muhtar Yılmazer, Engin Gerçeker, Cüneyt Zihni, Timur Meşe
Background: The aim of this study is to evaluate the role of leukotriene B4, an inflammatory mediator, in the development of pulmonary hypertension in paediatric patients with CHD with left-right shunt. Methods: The study included forty patients with CHD with left-right shunts. Based on haemodynamic data obtained from cardiac diagnostic catheterisation, 25 patients who met the criteria for pulmonary
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Removal of central venous catheter using Evolution® Rotating Dilator Cardiol. Young (IF 1.0) Pub Date : 2024-03-06 Koichi Takamizawa, Eriko Hasumi, Katsuhito Fujiu, Ryo Inuzuka
We experienced the first case of a difficult-to-extract central venous catheter removed with a pacemaker lead removal system: a 14-year-old boy with Hirschsprung’s disease who had repeated catheter infections that could not be removed by traction. Because the catheter lumen was occluded, a suture was tied around the end of the catheter and the catheter was removed with a rotating dilator.
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Bilateral ductal stenting in an infant with pulmonary atresia and ventricular septal defect, non-confluent pulmonary arteries, and bilateral arterial duct Cardiol. Young (IF 1.0) Pub Date : 2024-03-05 Paul Padovani, Mohamedou Ly, Alban-Elouen Baruteau
Pulmonary atresia with ventricular septal defect, non-confluent pulmonary arteries, and bilateral arterial duct is a rare and complex CHD. Physiologic ductal closure may lead to life-threatening hypoxia. We present a case of successful bilateral ductal stenting as a bridge to further lower-risk surgical repair.
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Impact of obstructive sleep apnoea on cardiovascular outcomes and mortality in young adults with congenital heart anomalies: insights from the national inpatient sample (2019) Cardiol. Young (IF 1.0) Pub Date : 2024-03-05 Ankit Vyas, Rupak Desai, Nitin Ghadge, Prerna Bansal, Harika Varma Chintalapalli Patta, Maharshi Raval, Akhil Jain, Tripti Gupta, Harshil Patel, Ashok Kondur, Carl J. Lavie
Background: Obstructive sleep apnoea is a common sleep disorder, and adult congenital heart disease (CHD) is also a significant burden on the population. Early diagnosis and treatment are important for improving quality of life and reducing the risk of health complications. The limited research on obstructive sleep apnoea and adult CHD highlights the need for further investigation into the relationship
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Organisation of paediatric echocardiography laboratories and governance of echocardiography services and training in Europe: current status, disparities, and potential solutions. A survey from the Association for European Paediatric and Congenital Cardiology (AEPC) imaging working group Cardiol. Young (IF 1.0) Pub Date : 2024-03-05 Massimiliano Cantinotti, Inga Voges, Owen Miller, Francesca Raimondi, Heynric Grotenhuis, Tara Bharucha, Almudena Ortiz Garrido, Emanuela Valsangiacomo, Arno Roest, Jan Sunnegårdh, Thomas Salaets, Henrik Brun, Diala Khraiche, Antonis Jossif, Michiel Schokking, Anna Sebate-Rotes, Jaroslaw Meyer-Szary, Antigoni Deri, Laurens Koopman, Ulrike Herberg, Gideon du Marchie Sarvaas, Markku Leskinen, Bertrand
Background: There is limited data on the organisation of paediatric echocardiography laboratories in Europe. Methods: A structured and approved questionnaire was circulated across all 95 Association for European Paediatric and Congenital Cardiology affiliated centres. The aims were to evaluate: (1) facilities in paediatric echocardiography laboratories across Europe, (2) accredited laboratories, (3)
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Sinus venosus atrial septal defect presenting with platypnea-orthodeoxia syndrome in the setting of COVID-19 infection Cardiol. Young (IF 1.0) Pub Date : 2024-03-05 Courtney H. Thomas, Jeffrey D. Zampi, Michael R. Joynt
Platypnea-orthodeoxia syndrome is characterised by hypoxemia and dyspnoea while upright that resolves when supine, typically associated with an interatrial communication. We present a case of platypnea-orthodeoxia syndrome associated with a sinus venosus atrial septal defect in a patient with multiple possible aetiologies of hypoxemia, including COVID-19 infection. Cardiac catheterisation with provocative
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A case of Carvajal syndrome presenting with dilated cardiomyopathy Cardiol. Young (IF 1.0) Pub Date : 2024-03-04 Sule Arıcı, Figen Akalın, Bilgen Bilge Geckinli
Objectives: Carvajal syndrome is a very rare autosomal recessive cardiocutaneous disorder caused by a desmosomal mutation in exon 24 of the desmoplakin gene. It manifests with woolly hair, epidermolytic palmoplantar keratoderma, and arrhythmogenic right ventricular cardiomyopathy. We herein present a patient with heart failure and dilated cardiomyopathy who was diagnosed with Carvajal syndrome because
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Prevalence and clinical significance of late gadolinium enhancement in children and adolescents with hypertrophic cardiomyopathy: a systematic review and meta-analysis Cardiol. Young (IF 1.0) Pub Date : 2024-03-04 Leong Tung Ong, Si Wei David Fan
Objectives: Hypertrophic cardiomyopathy is the leading cause of sudden cardiac death among the paediatric population. The aim of this study is to investigate the prevalence and clinical significance of late gadolinium enhancement, as assessed by cardiac MRI, in paediatric hypertrophic cardiomyopathy. Methods: A systematic literature search was conducted in PubMed, SCOPUS, and Ovid SP to identify relevant
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Travel insurance: an adult CHD patient’s perspective Cardiol. Young (IF 1.0) Pub Date : 2024-03-04 Aravind Mekala Sai, Omar Mubarak, Lucy Hudsmith, Nada Al-Sakini
Many adult CHD patients encounter difficulties in obtaining affordable travel insurance. We aimed to assess their travel habits and perspectives through a questionnaire. Our results indicate that many adult CHD patients use travel insurance but incur a premium due to their condition. There is an urgent need to provide better guidance to these patients on travel insurance options available to them.
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Fusion imaging for guidance of pulmonary arteriovenous malformation embolisation with minimal radiation and contrast exposure Cardiol. Young (IF 1.0) Pub Date : 2024-03-01 Catalina Vargas-Acevedo, Ernesto Mejia, Jenny E. Zablah, Gareth J. Morgan
Hereditary haemorrhagic telangiectasia is an inherited disorder characterised by vascular dysplasia that leads to the development of arteriovenous malformations. Pulmonary arteriovenous malformations occur in approximately 30% of patients with haemorrhagic telangiectasia. Given the complex characteristics of haemorrhagic telangiectasia lesions, the application of three-dimensional fusion imaging holds
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Rare case of total anomalous pulmonary venous return into the right atrium in situs solitus Cardiol. Young (IF 1.0) Pub Date : 2024-02-27 Elio Caruso, Silvia Farruggio, Norman H. Silverman
We report an uncommon case report of total anomalous pulmonary venous returns into the right atrium at the base of the superior caval vein’s ostium without a sinus venosus defect, in situs solitus, without vertical vein or a posterior pulmonary venous confluence.
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Use of temporary tracheostomy occlusion to reduce the risk of sternal wound infection after sternotomy in congenital cardiac surgery Cardiol. Young (IF 1.0) Pub Date : 2024-02-27 Julien B. Azimzadeh, Douglas R. Sidell, Karthik Balakrishnan, Roshni Mathew, Ritu Asija, Michael J. Rutter, Kara D. Meister
Objective: To describe a method of reducing the risk of sternal wound infection after sternotomy in children with a pre-existing tracheostomy. To report our outcomes using this method from 1 January, 2013 to 31 August, 2023. Methods: We describe a method for temporarily occluding the tracheal stoma with a removable implant with the primary goal of reducing the risk of sternotomy wound infection by
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Days alive and out of hospital for children born with single-ventricle heart disease Cardiol. Young (IF 1.0) Pub Date : 2024-02-27 Cathlyn K. Medina, Neel K. Prabhu, Isaac S. Alderete, Lauren E. Parker, Hoe King Lim, Mary E. Moya-Mendez, Lillian Kang, M. Jay Campbell, Douglas M. Overbey, Joseph W. Turek, Nicholas D. Andersen
Background: This study describes the illness burden in the first year of life for children with single-ventricle heart disease, using the metric of days alive and out of hospital to characterize morbidity and mortality. Methods: This is a retrospective single-centre study of single-ventricle patients born between 2005 and 2021 who had their initial operation performed at our institution. Patient demographics
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Aortic dilation in adults with repaired tetralogy of Fallot: a single-centre study Cardiol. Young (IF 1.0) Pub Date : 2024-02-27 Tahereh Saedi, Rashide Siami, Amir J. Ghaffari, Danial Farmani, Sedigheh Saedi
Background: Tetralogy of Fallot is the most prevalent cyanotic CHD. With the advent of advanced surgical methods, the majority of tetralogy of Fallot patients reach adulthood. However, many need re-intervention for the residual anomalies including residual right ventricular outflow obstruction, pulmonary regurgitation, residual ventricular septal defects, and progressive aortic dilatation. Aortic dilation
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A single-institutional experience with 36 children less than 5 kilograms supported with the Berlin Heart: Comparison of congenital versus acquired heart disease Cardiol. Young (IF 1.0) Pub Date : 2024-02-16 Mark S. Bleiweis, Omar M. Sharaf, Joseph Philip, Giles J. Peek, Yuriy Stukov, Gregory M. Janelle, Andrew D. Pitkin, Kevin J. Sullivan, Connie S. Nixon, Dan Neal, Jeffrey P. Jacobs
Objectives: We reviewed outcomes in all 36 consecutive children <5 kg supported with the Berlin Heart pulsatile ventricular assist device at the University of Florida, comparing those with acquired heart disease (n = 8) to those with congenital heart disease (CHD) (n = 28). Methods: The primary outcome was mortality. The Kaplan-Meier method and log-rank tests were used to assess group differences in
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Bosentan in the treatment of persistent pulmonary hypertension in newborns: a systematic review and meta-analysis Cardiol. Young (IF 1.0) Pub Date : 2024-02-08 Ning Gao, Yuanyuan Lv, Yanbin Cui, Pengchun Wang, Xin He
Background: Persistent pulmonary hypertension of the newborn is a life-threatening condition that affects about 1–2 per 1,000 live births worldwide. Bosentan is an oral dual endothelin receptor antagonist that may have a beneficial effect on persistent pulmonary hypertension of the newborn by reducing pulmonary vascular resistance and improving oxygenation. However, its role in persistent pulmonary
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Percutaneous closure of patent ductus arteriosus versus surgical treatment in low-birth-weight preterms: a systematic review and meta-analysis Cardiol. Young (IF 1.0) Pub Date : 2024-02-08 Camila Dos Santos Melchior, Gabriel Rezende Neves, Bruna Letícia de Oliveira, Ana Carolina Toguchi, Jesana Costa Lopes, Marcos Alves Pavione, Shirley Katherine Tinajero Enríquez
Introduction: The optimal management of a patent ductus arteriosus in a population of preterm infants is controversial. Traditionally, when the patent ductus arteriosus does not close either with conservative treatment or in response to pharmacological therapy, the only option is surgical closure. However, transcatheter occlusion might provide a therapeutic alternative. Methods: We searched PubMed
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A rare variant of scimitar syndrome characterised by right pulmonary vein drainage to portal vein with eventeration of diaphragm Cardiol. Young (IF 1.0) Pub Date : 2024-02-08 Thejaswi Puthiyedath, Pramod Sagar, Kothandam Sivakumar
While infradiaphragmatic total anomalous pulmonary venous drainage to portal vein is well described, hemianomalous drainage of right pulmonary veins to portal vein in Scimitar syndrome has not yet been reported.
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Congenital dual anterior interventricular artery Cardiol. Young (IF 1.0) Pub Date : 2024-02-05 Miao Hao, Qi An, Shuhua Luo
Dual anterior interventricular artery is a rare type of CHD. We reported a fifteen-year-old girl who underwent CT angiography that demonstrated one anterior interventricular artery from aorta and another from pulmonary artery.
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Assessing autonomic activity and prognostic risk factors comparing multisystem inflammatory syndrome and isolated viral myocarditis/myopericarditis Cardiol. Young (IF 1.0) Pub Date : 2024-02-02 Derya Duman, Derya Karpuz, Bahar Taşdelen, Necdet Kuyucu
Introduction and aim: In pediatric multisystem inflammatory syndrome and isolated viral myocarditis/myopericarditis, autonomic nervous system function can be evaluated by a non-invasive method called heart rate variability. This study aims to evaluate heart rate variability in these two groups by comparing them with each other. This is the first study assessing these values in these two groups of patients
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Circulating leptin is associated with adverse vascular changes in young adult survivors of childhood cancer Cardiol. Young (IF 1.0) Pub Date : 2024-02-02 Olof Broberg, Tobias Feldreich, Constance G. Weismann, Ingrid Øra, Thomas Wiebe, Johan Ärnlöv, Petru Liuba
Introduction: Proteomics may help discover novel biomarkers and underlying mechanisms for cardiovascular disease. This could be useful for childhood cancer survivors as they show an increased risk of cardiovascular disease. The aim of this study was to investigate circulating cardiovascular proteins in young adult survivors of childhood cancer and their relationship to previously reported subclinical
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“Quality of life” analysis in the long-term follow-up after “Fontan” palliation for CHDs—a single-centre experience Cardiol. Young (IF 1.0) Pub Date : 2024-01-30 Susann Brosig, Robert Wagner, Rabie Twal, Sabine Meier, Marcel Vollroth, Franziska Markel, Ingo Dähnert, Martin Kostelka, Christian Paech
Background: Complex CHDs are life threatening, and surgical treatment is needed for survival. Fontan palliation led to a significant increase in survival rates during the last decades. Consequently, quality of life became more essential. While a reduced quality of life compared to healthy children has been reported, detailed knowledge about individual quality of life and particular areas is lacking
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Septic pulmonary embolism complicates postoperative tetralogy of fallot: unveiling pulmonary artery pseudoaneurysms Cardiol. Young (IF 1.0) Pub Date : 2024-01-29 Juan Xu, Di Huang, Renhui Cai
A 12-year-old female with pulmonary artery stenosis developed pseudoaneurysms due to septic embolism, requiring close follow-up.
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Impact of early postoperative haemodynamic and laboratory parameters on outcome after the Fontan procedure Cardiol. Young (IF 1.0) Pub Date : 2024-01-29 Chiara Di Padua, Takuya Osawa, Birgit Waschulzik, Gunter Balling, Thibault Schaeffer, Helena Staehler, Nicole Piber, Alfred Hager, Peter Ewert, Jürgen Hörer, Masamichi Ono
Objective: To identify early postoperative haemodynamic and laboratory parameters predicting outcomes following total cavopulmonary connection. Methods: Patients who underwent total cavopulmonary connection between 2012 and 2021 were evaluated. Serial values of mean pulmonary artery pressure, mean arterial pressure, peripheral oxygen saturation, and lactate levels were collected. The influence of these
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Rare cardiac tumour-nodular fasciitis Cardiol. Young (IF 1.0) Pub Date : 2024-01-29 Natraj Ballal, Neehar Haryadi, Karl Reyes
Left ventricular tumour is a rare condition in children. The causes include vegetations, thrombus, and fibroma. 2-year-old asymptomatic female presented with an innocent heart murmur at 6 months of age. Subsequent follow-ups at 18 months of age showed left ventricular mass. Surgical pathology revealed “nodular fasciitis.” This type of tumour has never been described in the heart before.
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A rare case of severe Ebstein’s anomaly and hepatoblastoma in a neonate Cardiol. Young (IF 1.0) Pub Date : 2024-01-25 Julia R. Bendorf, Cecilia A. Albaro, Harma K. Turbendian
Primary liver tumours in neonates with single-ventricle palliation are exceedingly rare. We present the first reported case of neonatal hepatoblastoma with severe Ebstein’s anomaly following Starnes procedure. The patient’s postoperative course highlights the challenges and complications in simultaneous management of these diagnoses. Transition from shunted single-ventricle physiology to bidirectional
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Repair of iatrogenic left pulmonary artery to left atrial appendage fistula using a covered CP stent: a case report Cardiol. Young (IF 1.0) Pub Date : 2024-01-25 Hisako Kakimoto, Takanari Fujii, Hideshi Tomita
We report a case of iatrogenic left pulmonary artery–left atrial appendage fistula following percutaneous transluminal angioplasty for residual pulmonary artery stenosis in an 11-year-old boy. This rare complication could have been predicted by understanding the anatomical relationship of these structures. In this study, simulation using three-dimensional printing greatly contributed to successful
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Spontaneous resolution of an intrapericardial thrombus as a complication of pericardiocentesis in a neonate Cardiol. Young (IF 1.0) Pub Date : 2024-01-25 Joy Crombez, Wendy Dewals, Laura Muiño Mosquera, Thomas Martens, Karlijn Van Damme, Luc Bruyndonckx
We present the case of a premature neonate with pericardial effusion secondary to extravasation of total parenteral nutrition from a mispositioned/migrated umbilical venous catheter. Emergency pericardiocentesis was complicated by an intrapericardial thrombus, which was managed conservatively with spontaneous resolution within 24 hours. This case illustrates that the rare complication of an intrapericardial
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The effects of percutaneous branch pulmonary artery interventions on exercise capacity, lung perfusion, and right ventricular function in biventricular CHD: a systematic review Cardiol. Young (IF 1.0) Pub Date : 2024-01-23 Renée S. Joosen, Jules P. B. Frissen, Agnes van den Hoogen, Gregor J. Krings, Michiel Voskuil, Martijn G. Slieker, Johannes M. P. J. Breur
Background: Branch pulmonary artery stenosis is common after surgical repair in patients with biventricular CHD and often requires reinterventions. However, (long-term) effects of percutaneous branch pulmonary artery interventions on exercise capacity, right ventricular function, and lung perfusion remain unclear. This review describes the (long-term) effects of percutaneous branch pulmonary artery
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Nutritional considerations for people living with a Fontan circulation: a narrative review Cardiol. Young (IF 1.0) Pub Date : 2024-01-23 Melanie Clode, Derek Tran, Avik Majumdar, Julian Ayer, Suzie Ferrie, Rachael Cordina
The population of people living with a Fontan circulation are highly heterogenous, including both children and adults, who have complex health issues and comorbidities associated with their unique physiology throughout life. Research focused on nutritional considerations and interventions in the Fontan population is extremely limited beyond childhood. This review article discusses the current literature
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Paediatric heart transplantation: life-saving but not yet a cure Cardiol. Young (IF 1.0) Pub Date : 2024-01-23 Robert Boucek, Richard Chinnock, Janet Scheel, Shriprasad R. Deshpande, Simon Urschel, James Kirklin
In the 1980s, heart transplantation was the first successful treatment for infants born with hypoplastic left heart syndrome. Infants who have required heart transplantation benefit from immunologic “advantages,” including long-term survival free from cardiac allograft vasculopathy. Currently ∼ 90% of children undergoing a heart transplant are reaching their first-year anniversary and the clinical
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Prevalence of electrocardiographic abnormalities among Iranian children and adolescents and associations with blood pressure and obesity: findings from the SHED LIGHT study Cardiol. Young (IF 1.0) Pub Date : 2024-01-18 Mohammad Rafie Khorgami, Yousef Rezaei, Avisa Tabib, Alireza A. Ghavidel, Gholamreza Omrani, Ahmad Mohebbi, Mohammad Mehdi Peighambari, Zahra Emkanjoo, Mehrdad Oveisi, Ghasem Hajianfar, Bahareh Kazemborji, Saeid Hosseini, Niloufar Samiei
Background: There are few studies for detecting rhythm abnormalities among healthy children and adolescents. The aim of the study was to investigate the prevalence of abnormal electrocardiographic findings in the young Iranian population and its association with blood pressure and obesity. Methods: A total of 15084 children and adolescents were examined in a randomly selected population of Tehran city
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Life-threatening pulmonary haemorrhage treated with coil embolisation followed by lobectomy in a patient with KCNT1 mutation Cardiol. Young (IF 1.0) Pub Date : 2024-01-17 Dhaval Chauhan, Pieter Alexander Verhoeven, Utkarsh Kohli, Jai P. Udassi, Christopher E. Mascio
KCNT1 mutations are associated with childhood epilepsy, developmental delay, and vascular malformations. We report a child with a likely pathogenic KCNT1 mutation (c.1885A>C, p.Lys629Glu) with recurrent pulmonary haemorrhage due to aortopulmonary collaterals successfully managed with coil embolisation followed by right upper lobectomy.
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Effective control of refractory pulmonary hypertension with iloprost inhalation in an infant with congenital absence of the right pulmonary artery: a case report Cardiol. Young (IF 1.0) Pub Date : 2024-01-15 Chu-Yuan Hsiao, Wen-Hsien Lu
Unilateral absence of the pulmonary artery is a rare congenital cardiovascular anomaly that can lead to pulmonary hypertension and poor outcomes. We report the case of a 1-month-old infant with isolated unilateral absence of the pulmonary artery and severe pulmonary hypertension on the right and left sides, respectively. The patient was unresponsive to multiple medications for pulmonary hypertension
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The oxygen uptake efficiency slope in adults with CHD: group validity Cardiol. Young (IF 1.0) Pub Date : 2024-01-15 J. M. Redfern, S. Hawkes, A. Bryan, D. Cullington, R. Ashrafi
The maximal oxygen uptake (V02 max) is a well-validated measure of cardiorespiratory function that is calculated during a maximal cardiopulmonary exercise test. V02 max enables physicians to objectively assess cardiopulmonary function to aid in decision-making for patients with CHD. A significant proportion of these patients however are unable to achieve a maximal exercise test, and as such, there
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Use of a modified microvascular plug to modify fenestration flow in a rapidly failing Fontan Cardiol. Young (IF 1.0) Pub Date : 2024-01-15 Nicola McCay, Philip Roberts, Kevin Walsh
We report a case of an alternative transcatheter use of the modified Medtronic microvascular plug to modify fenestration stent flow in a patient with a rapidly deteriorating clinical condition. This four-year-old boy developed severe cyanosis following fenestration stent insertion, initially placed due to prolonged drainage post-Fontan with extra-cardiac conduit. In April 2023, he underwent urgent
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Utility of simultaneous triple balloon inflation technique through a single 6-French sheath in treating pulmonary vein stenosis Cardiol. Young (IF 1.0) Pub Date : 2024-01-15 Bassel Mohammad Nijres, Osamah Aldoss
Pulmonary vein stenosis continues to pose significant challenges in children, frequently requiring repeated cardiac catheterisation procedures. This report describes a successful application of a “triple kissing balloon” technique to treat complex pulmonary vein stenosis in two patients, all accomplished with the use of a single 6-French sheath.
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The experience of fathers of children hospitalised with advanced heart disease Cardiol. Young (IF 1.0) Pub Date : 2024-01-10 Chase Samsel, Jeffrey R. Reichman, Jessica A. Barreto, David W. Brown, Kevin Hummel, Lynn A. Sleeper, Elizabeth D. Blume
Background: There are little reported data on the perspectives of fathers caring for children with chronic conditions. Although survival of children with advanced heart disease has improved, long-term morbidity remains high. This study describes the experience and prognostic awareness of fathers of hospitalised children with advanced heart disease. Methods: Cross-sectional survey study of parents caring
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Reduced morbidity with early surgical ligation of patent ductus arteriosus in extremely low birth weight infants: a retrospective single-centre study Cardiol. Young (IF 1.0) Pub Date : 2024-01-10 Katherine A. Loeffler, Shashank P. Behere, Patricia K. Williams, Yuki Nakamura, Harold M. Burkhart, Matthew D. Campbell
Introduction: Failure of the patent ductus arteriosus to close is common among extremely low birth weight neonates and has been associated with increased morbidities. The objective of this study was to compare outcomes between early and late surgical ligation in extremely low birth weight patients. Methods: This was a single-centre retrospective cohort study of infants who required surgical closure
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Percutaneous pulmonary valve implantation in a patient with a single pulmonary artery and distal narrowing Cardiol. Young (IF 1.0) Pub Date : 2024-01-08 Judyta Szeliga, Tomasz Moszura, Sebastian Góreczny
Percutaneous pulmonary valve implantation is established as a safe and effective method of treating patients with disfunction of right ventricular outflow tract. Modifications of this method allow for an increasingly wider use of this less invasive treatment. We present a staged percutaneous pulmonary valve implantation into a single-branch pulmonary artery in a paediatric patient with tetralogy of
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Percutaneous pulmonary valve implantation in children and adults with an age and gender-specific analysis Cardiol. Young (IF 1.0) Pub Date : 2024-01-08 Charalampos Kotidis, Neeraj Nirmal, Marinos Kantzis
Background: There are limited studies with medium-term follow-up following percutaneous pulmonary valve implantation and no studies with a gender-specific analysis. Aims: To report clinical outcomes up to five years following percutaneous pulmonary valve implantation using the two most common balloon expandable valves in a mixed population of paediatric and adult patients with an age and gender-specific
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Association of European Paediatric and Congenital Cardiology practical recommendations for surveillance and prevention of cardiac disease in childhood cancer survivors: the importance of physical activity and lifestyle changes From the Association of European Paediatric and Congenital Cardiology Working Group Sports Cardiology, Physical Activity and Prevention, Working Group Adult Congenital Heart Cardiol. Young (IF 1.0) Pub Date : 2024-01-04 Sabine Kesting, Ugo Giordano, Jochen Weil, Colin J. McMahon, Dimpna C. Albert, Claire Berger, Werner Budts, Peter Fritsch, Erzsébet V. Hidvégi, Renate Oberhoffer-Fritz, Giuseppe M. Milano, Annette Wacker-Gußmann, Vesna Herceg-Čavrak
Background: Childhood cancer survivors are at increased risk of developing cardiovascular diseases, presenting as the main causes of morbidity and mortality within this group. Besides the usual primary and secondary prevention in combination with screening during follow-up, the modifiable lifestyle factors of physical activity, nutrition, and body weight have not yet gained enough attention regarding
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Aortic valvar atresia with a normal-sized left ventricle in an adolescent Cardiol. Young (IF 1.0) Pub Date : 2024-01-03 Sourabh Goswami, Rengarajan Rajagopal, Surender Deora
Atresia of the aortic valve is usually associated with hypoplasia of the mitral valve and the left ventricle. In very rare cases, a ventricular septal defect may be associated with aortic atresia, when left ventricle and mitral valve are normal-sized, due to the presence of an outflow for the left ventricle through the ventricular septal defect. We present the multi-modality imaging findings of an
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Word of caution: silent late device embolisation after perimembranous ventricular septal defect closure in a 6-Kg infant Cardiol. Young (IF 1.0) Pub Date : 2024-01-03 Raymond N. Haddad, Zakhia Saliba
We report on a 6-month-old infant (6 Kg/ 64 cm) with perimembranous ventricular septal defect (absent sub-aortic rim, 10 mm left ventricular entry, and 4 and 6 mm right ventricular exists) and successful retrograde closure using an 8x6 mm KONAR-MF™ VSD occluder (Lifetech, China). Immediate and 48 hours post-procedure ultrasounds showed an accurately positioned device and two jets of mild-to-moderate
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Myxomatous degeneration of cardiac valves in a fetus with 6q25.1 (TAB2) deletion Cardiol. Young (IF 1.0) Pub Date : 2024-01-03 Balaganesh Karmegaraj
Myxomatous degeneration of one or more cardiac valves has been reported in trisomy 18, Noonan, Marfan, and Ehlers-Danlos syndromes. 6q25.1 (TAB2) deletion is one of the notable causes for myxomatous degeneration of cardiac valves. Whole exome sequencing must be considered in these subsets of cases for effective prenatal counselling. A 23-week fetus presented with cardiomegaly, redundant myxomatous
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18F-fluorodeoxyglucose positron emission tomography/CT in the diagnosis of right-sided endocarditis in children and adults with infective endocarditis Cardiol. Young (IF 1.0) Pub Date : 2024-01-02 Sezen Ugan Atik, Perver Arslan, Seçkin Bilgiç, Kerim Sonmezoglu, Erman Cilsal, Selman Gokalp, Alper Guzeltas
Objective: Infectious endocarditis poses a diagnostic challenge due to its highly variable clinical presentation. To establish a definitive diagnosis, different imaging modalities are essential. In recent years, positron emission tomography/CT has gained increasing significance in diagnosing infective endocarditis; however, its application in the pediatric age group remains limited. This study encompasses
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Influence of the COVID-19 pandemic on the congenital heart surgery service in Lithuania Cardiol. Young (IF 1.0) Pub Date : 2024-01-02 Dominykas Budrys, Rūta Gegieckienė, Virgilijus Lebetkevičius, Rita Sudikienė, Virgilijus Tarutis, Karolis Jonas
Introduction: CHD is a unique group of medical pathologies. Literature worldwide reports significant decrements in the case volume of patients with these conditions due to the recent global pandemic of coronavirus disease 2019. The only centre providing congenital cardiac care for Lithuanian population is in a hospital which was the main medical institution for the sickest coronavirus disease 2019
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“In-patient echocardiography utilization post repair of congenital heart disease. Analysis of data from the Pediatric Health Information System from 2010 to 2019” Cardiol. Young (IF 1.0) Pub Date : 2024-01-02 Adam M. Skaff, Nishma G. Valikodath, Justin Godown, David A. Parra
Background: Echocardiography is a key diagnostic tool for medical decision-making following congenital heart surgery. Overall utilisation of echocardiography for specific congenital heart lesions following cardiac surgery has not previously been reported. This study aims to assess echocardiogram utilisation following the surgical repair of CHD to describe the variation in use across centres and provide