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What are congenital melanocytic nevi? Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-03-17
Congenital melanocytic nevi (CMN) are special types of moles. CMN happen when extra pigment-making cells (melanocytes) grow in a baby's skin while the baby is forming before birth. They are not caused by anything their parent did or didn’t do during pregnancy. These moles are there when the baby is born, stay on the skin for life, and grow as the child grows.
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¿Qué son nevos melanocíticos congénitos? Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-03-17
Los nevos melanocíticos congénitos (NMC) son un tipo especial de lunares. Los NMC ocurren cuando las células que hacen los pigmentos (melanocitos) crecen en exceso en la piel de un feto en formación antes de nacer. No son causados por nada que la madre haya hecho ni haya dejado de hacer durante el embarazo. Estos lunares ya están allí cuando el bebé nace, se mantienen en su piel de por vida y aumentan
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Distal toxic acral erythema and mucositis secondary to 6‐mercaptopurine in a thiopurine methyltransferase “super shunter” Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-03-14 Sydney Smith, Daniel Grove
Toxic erythema of chemotherapy is a broad but useful diagnosis used to summate the non‐infectious, non‐allergic, and reproducible reaction of certain chemotherapeutics. Due to overlapping chemotherapy side effects and often multiple drug exposures, identification of a singular culprit drug is challenging for dermatologists. Herein, we report a patient with 6‐mercaptopurine (6‐MP) toxic erythema confirmed
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Neonatal nasal necrosis: Case series and brief review Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-03-09 Jamie L. Karch, David Grand, Ariana G. Diaz, Leah Belazarian, Julianne A. Mann
There is limited information available on pressure‐related neonatal nasal injuries. We present three neonates born with erythema and purpura of the nasal tip that subsequently ulcerated, then evolved into a thick eschar. Each healed well with conservative management but left behind significant scarring. The sharp demarcation and location of the lesions were suggestive of hypoxic tissue damage akin
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Diffuse neurofibroma with hypertrichosis in a toddler Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-03-09 Robert P. Bower, Paul Leiphart, Thomas Samson, Klaus F. Helm, Andrea Zaenglein
Diffuse neurofibroma is a rare type of neurofibroma uncommonly reported in infancy. It is a slow growing tumor originating in the peripheral nerve sheath. We present the case of a 17‐month‐old boy with diffuse neurofibroma of the scalp associated with hypertrichosis. His genetic and clinical workup for neurofibromatosis was negative.
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Eye and lid involvement as an uncommon feature of pemphigus foliaceus in a pediatric patient Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-03-09 Valeria F. Garza‐Dávila, Adalberto Santana‐Gutiérrez, Natalia Zapata‐Salazar, Osvaldo Vázquez‐Martínez, Jorge Ocampo‐Candiani, Marissa L. Fernández‐de Luna, Karim Mohamed‐Noriega, Erika Alba‐Rojas
Pemphigus foliaceus (PF) is an autoimmune blistering disorder which affects the superficial layers of the epidermis with rare mucosal involvement. We present the case of a 12‐year‐old girl with PF involving the eyes and eyelids. A literature review of pediatric nonendemic PF revealed another two cases with ocular manifestations. Eyelid involvement is an uncommon feature of PF that should be properly
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Angiolymphoid hyperplasia with eosinophilia and Kimura disease: A case report and literature review Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-03-09 Elizabeth Botto, Paul Rodriguez‐Waitkus, Sharon E. Albers
Angiolymphoid hyperplasia with eosinophilia (ALHE) is a benign vascular proliferative condition, typically presenting as subcutaneous nodules in the head and neck region of middle‐aged women. Kimura disease (KD) is a benign condition that presents with subcutaneous nodules in a similar distribution with lymphadenopathy and eosinophilia, typically in Asian adult males. These diseases are often discussed
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“Our Hair, Our Strength, Our Identity”: Native American reflections and what dermatologists can learn Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-03-09 Dante Rangel, Evan Choate, Yolandra Toya, Anthony Fleg, Aimee C. Smidt
Issues of health equity are rightfully in the national spotlight. Here we present a narrative piece on the sacred importance of hair and its ties to cultural identity among many Native communities in the United States. We introduce unique values ascribed to hair in some Native cultures, and include examples of how hair has played an important role in both abuse and generational trauma for many individuals
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Closing the gap: Enhancing quality pediatric dermatologic care through project Extension for Community Healthcare Outcomes (ECHO) Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-03-08 Travis Jackson, Megan Mosca, Bin Ge, Jonathan Dyer, Kara Braudis, Karen Edison, Mirna Becevic
This study focused on evaluating Extension for Community Healthcare Outcomes (ECHO) participating primary care clinician's (PCC's) diagnostic and treatment accuracy of pediatric dermatologic conditions. To evaluate this, pediatric cases presented to Dermatology ECHO by PCCs with questions regarding diagnosis, treatment regimen, or both were analyzed. After PCC case presentation, the hub team of dermatologists
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Two siblings with uncombable hair syndrome: A new pathogenic variant Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-03-08 Carlos Calvo‐Asín, Sara I. Palencia‐Pérez, Juan F. Quesada‐Espinosa, Jose Puig‐Buendia, Raquel Cavestany‐Rodríguez, Virginia Velasco‐Tamariz
Two siblings presented with straw‐colored, frizzy, and wiry hair. They had no associated abnormalities and no family history of abnormal hair. Trichoscopy showed the longitudinal groove in the hair shafts, characteristic of uncombable hair syndrome. Molecular genetic analysis revealed a new pathogenic variant (c.1374dup; p. Val459ArgfsTer15) in PADI3, not previously described.
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Four‐month‐old with severe PIK3CA‐related overgrowth spectrum disorder successfully treated with alpelisb Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-03-06 María‐Laura Cossio, Josefina Rodríguez, Juan Carlos Flores, Florencia De Barbieri, Álvaro Flores, José Marín, Carla Florin, Francisco Cuevas, Monserrat Gutiérrez
PIK3CA‐related overgrowth spectrum (PROS) encompasses different clinical entities caused by somatic activating mutations in PIK3CA. Among PROS, CLOVES syndrome represents a severe phenotype with poor survival rate. We present the case of a 4‐month‐old girl with CLOVES syndrome successfully treated with alpelisib, a PIKC3A inhibitor.
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Violaceous papules on the limbs of a 10‐year‐old girl Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-03-06 Lauren G. Yi, Anisha P. Valluri, Juanita Duran Rincon, Shyam Raghavan, Barrett J. Zlotoff
CASE PRESENTATION A 10-year-old Caucasian girl presented with a 1-year history of a pruritic, nontender, pustular rash on her legs and several weeks of oral ulcers. Medical history was notable for 6 months of abdominal pain and hematochezia. The rash started on her ankles and progressed to involve her torso, arms, and face. Physical examination revealed violaceous papules, some surmounted by pustules
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Oral sirolimus for the treatment of juvenile xanthogranuloma: Report of two pediatric cases Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-03-06 Michelle Toker, Fatema Esaa Hassonjee, John Amodio, Morris C. Edelman, Kristina I. Emeghebo, Carolyn Fein Levy, Sheila Shaigany
Juvenile xanthogranuloma (JXG) with extensive cutaneous or visceral organ involvement is often associated with high morbidity and treatment commonly involves surgical excision, radiotherapy, systemic steroids, or chemotherapy. Sirolimus, a mammalian target of rapamycin (mTOR) inhibitor, is an oral antitumor and immunosuppressive therapy used to treat various neoplastic disorders, including histiocytic
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Relationship between long‐acting reversible contraception and acne in a cohort of adolescents and young adults Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-03-06 Markus D. Boos, Morgan E. Ryan, Carly Milliren, Sarah Golub, Sofya Maslyanskaya, Michelle Escovedo, Amy DiVasta, Sarah Pitts
BackgroundThe use of progestin‐only long‐acting reversible contraception (LARC) may be a risk factor for acne. Few studies have focused primarily on the effects of hormonal LARC on the development or exacerbation of acne in adolescents and young adults. We sought to understand the incidence and management of acne following hormonal LARC insertion in this adolescent/young adult population.MethodsA secondary
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Transient infantile lingual leukoplakia: An underrecognized cause of white tongues in infancy Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-27 Joseph M. Lam, Agnes Schwieger-Briel, Tram Nguyen, Antonio Torrelo
We have observed a distinct phenomenon of transient oral lingual leukoplakia in infancy and report 22 healthy infants with gray–white plaques on the dorsal tongue with sparing of the tip from four medical centers in three countries. The onset of the eruption ranged from 1 week to 7 months of life and resolved in 19 patients (86%, with 3 patients lost to follow-up). None of the eight patients examined
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A review of hair removal modalities in pediatric patients: Ethical and clinical considerations Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-27 Eric Sanfilippo, Leslie Castelo-Soccio, Anna Yasmine Kirkorian
Unwanted hair is a common concern among patients presenting to pediatric dermatology clinics, and parents and patients alike inquire about the safety of methods employed for elective removal. Various methods of hair removal exist with different levels of invasiveness and permanence, from simple mechanical depilation to light-based therapies. All methods of hair removal appear to be safe and generally
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Neutrophilic dermatosis in a patient with an IKZF1 variant and a review of monogenic autoinflammatory disorders presenting with neutrophilic dermatoses Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-27 Justina Guirguis, Sonia Iosim, Derek Jones, Maryel Likhite, Fei Chen, Chimene Kesserwan, Tatyana Gindin, Philip J. Kahn, David Beck, Vikash S. Oza, Kirsty Hillier
Monogenic diseases of immune dysregulation should be considered in the evaluation of children presenting with recurrent neutrophilic dermatoses in association with systemic signs of inflammation, autoimmune disease, hematologic abnormalities, and opportunistic or recurrent infections. We report the case of a 2-year-old boy presenting with a neutrophilic dermatosis, found to have a novel likely pathogenic
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Unexpected location of a pilonidal sinus Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-27 Carme Grande-Moreillo, Sara Fuentes-Carretero, Francesca Corella-Vicente, Jaume Margarit-Mallol
Pilonidal sinus disease is typically located in the sacrococcygeal area, although it has been described in other locations. We present a rare case of pilonidal sinus on the scalp and its management.
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Bier anemic spots, cyanosis, and urticaria-like eruption (BASCULE) syndrome in a 15-year-old male, responsive to high-dose fexofenadine Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-27 Elizabeth Keeling, Chantal Cotter, Sarah O'Mahony, Madonna Andrawis, Asad Salim
We describe an unusual presentation of Bier anemic spots, cyanosis, and urticaria-like eruption (BASCULE) syndrome in a 15-year-old male, recalcitrant to low-dose anti-histamines, which subsequently responded to high-dose fexofenadine.
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Berdazimer gel for molluscum contagiosum in patients with atopic dermatitis Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-27 Amy S. Paller, Lawrence J. Green, Nanette Silverberg, Stephen Stripling, Martina Cartwright, Carolyn Enloe, Nick Wells, Elaine Kearney Kowalewski, Tomoko Maeda-Chubachi
Controlling molluscum contagiosum (MC) infections is critical in atopic dermatitis (AD) management. This post hoc analysis assessed the efficacy and safety of berdazimer gel, 10.3% (topical, antiviral, nitric oxide–releasing medication) versus vehicle in MC patients with or without AD.
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No seroconversion in a retrospective study analyzing QuantiFERON TB-gold testing in pediatric psoriasis and hidradenitis suppurativa patients taking biologic therapy at an academic center in New York City Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-27 Apostolos Katsiaunis, Jade Conway, Shari R. Lipner
Guidelines are inconsistent regarding annual QuantiFERON® TB Gold (QFT) tests in children taking biologics for dermatological conditions, and there is limited research on seroconversion, especially in regions with high tuberculosis (TB) prevalence. A retrospective review of pediatric patients taking biologic treatment for psoriasis or hidradenitis suppurativa (HS) who had one baseline and at least
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Idiopathic aseptic facial granuloma: A retrospective study of 43 cases Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-27 Lola Kuperman Wilder, Antonela Lamberti, Paula Boggio, María Eugenia Abad, Paula C. Luna, Margarita Larralde
Idiopathic aseptic facial granuloma (IAFG) is an underrecognized pediatric skin disease, currently considered within the spectrum of rosacea. It usually manifests as a solitary, reddish, asymptomatic nodule on the cheek that resolves spontaneously.
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Unresectable infantile myofibroma discovered in utero Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-27 Shannon Gurley, Ben J. Friedman, Tor Shwayder
The authors present a case of a proliferative nodule located beneath an infant's lower lip that was initially discovered on prenatal ultrasound and fetal magnetic resonance imaging (MRI). Biopsy revealed a smooth muscle actin‐positive spindled cell proliferation with hemangiopericytoma‐like vessels consistent with infantile myofibromatosis (IM). Since the location prevented surgical management, the
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Pediatric dermatofibromas: Truncal predominance in younger children Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-27 Brenna G. Kelly, Joel C. Joyce, Melodee A. Liegl, Amy Pan, Karolyn A. Wanat, Leah Lalor
Pediatric dermatofibromas are considered rare in young children and have not been well characterized, often misdiagnosed clinically. We performed a retrospective case series of children younger than 18 years with histopathologically diagnosed dermatofibromas at our institutions and evaluated age at onset and diagnosis, sex, lesion location, and size, associated symptoms, change over time, and pre‐biopsy
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Pediatric hidradenitis suppurativa publication trends: 2012 to 2022 Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-27 Sarah E. Park, Terri Shih, Caitlyn Dagenet, Marcia Hogeling, Meagan Hughes, Justin Gillenwater, Vivian Y. Shi, Jennifer L. Hsiao
There is a paucity of bibliometric data on pediatric‐focused hidradenitis suppurativa (HS) publications. To better characterize research trends in pediatric HS and gaps in literature, we systematically searched PubMed between 2012 and 2022 for publications on pediatric HS and collected data on study design, topic, country, and level of evidence. Of 109 articles that met inclusion criteria, less than
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Amniotic membrane dressings for treatment of aplasia cutis in newborns Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-27 Maliheh Kadivar, Razieh Sangsari, Somayeh Rostamli, Soheila Sotoudeh, Kayvan Mirnia
BackgroundAplasia cutis congenita (ACC) is a rare congenital skin defect characterized by a focal or extensive absence of the epidermis, dermis, and occasionally, subcutaneous tissue. When the wound caused by this defect is wide or deep, various treatments are used, including skin grafting. The amniotic membrane (AM) is a biological dressing that facilitates re‐epithelialization as it contains mesenchymal
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Dermatitis versus nonaccidental trauma: A systematic review of initial pediatric misdiagnoses Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-24 Aliyah King, Elena Pope
Pediatric dermatitis and nonaccidental trauma (NAT) may have overlapping cutaneous presentations, posing a risk of misdiagnosis and subsequent emotional distress and further harm. Through a systematic literature review, we reviewed pediatric (<18 years old) patients investigated for both dermatitis and NAT.
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Treatment of congenital Langerhans cell histiocytosis with cobimetinib Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-22 Ghita Benjelloun, Charlotte Roquet‐Gravy, Liliane Marot, Léo‐Paul Secco, Pierre‐Paul Roquet‐Gravy, Marie Baeck, Audrey Bulinckx
We report a case of congenital multisystem Langerhans cell histiocytosis with cutaneous and hematopoietic involvement. After the failure of first‐line (vinblastine and prednisolone) and second‐line (vincristine and cytarabine) therapies, treatment with cobimetinib, a mitogen‐activated protein kinase (MEK) inhibitor, led to the remission of disease and a sustained response after 11 months of ongoing
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Bilateral accessory axillary breast tissue in a premenarchal female Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-17 Madelyn M. Class, Kelly McCoy, Alyson A. Melin, Farhaan Hafeez, Nadia Abidi, Andrew C. Krakowski
A 9-year-old premenarchal female presented to pediatric dermatology with a 6-month history of periodically tender, bilateral and symmetric axillary masses. Magnetic resonance imaging and subsequent surgical excision confirmed the diagnosis of bilateral accessory axillary breast tissue. Accessory axillary breast tissue is a rare condition seen most in pubertal, pregnant and breastfeeding women. However
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Linear IgA bullous dermatosis of childhood: Retrospective single‐center cohort Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-20 Katherine L. Wang, Julia S. Lehman, Dawn M. R. Davis
Linear IgA bullous dermatosis (LABD) is a rare autoimmune blistering disorder impacting children and adults. In this single‐center retrospective chart review of pediatric patients with LABD at a large tertiary referral center, we report the unifying and unique clinical features of 10 pediatric patients. Patients typically presented with the “cluster of jewels” sign (n = 6; 60%), mucous membrane involvement
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A case of STING‐associated vasculopathy with onset in infancy with novel STING1 variant Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-19 Kelly K. Barry, Julie S. Kranseler, Sarah N. Robinson
STING‐associated vasculopathy with onset in infancy (SAVI) is a rare, monogenic interferonopathy caused by gain‐of‐function variants in STING1 (TMEM173) characterized by systemic inflammation, cutaneous vasculopathy, and interstitial lung disease. We report a case of SAVI attributed to a novel STING1 p.R284T variant who demonstrated characteristic cutaneous features including telangiectasias, livedo
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Posterior reversible encephalopathy syndrome in the setting of IgA vasculitis Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-19 Noah Fanous, Emily Clarke, Moise L. Levy
IgA vasculitis (IgAV), formerly known as Henoch–Scholein purpura, is a small vessel vasculitis, most commonly seen in pediatric patients, that can affect numerous internal organs including the kidneys, lungs, gastrointestinal tract, and the central nervous system (CNS). CNS manifestations of this condition include hypertensive encephalopathy, thrombosis, optic neuropathy, seizures, CNS vasculitis,
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Phototherapy causing a purpuric eruption in a neonate Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-11 Frédéric Pelchat, Maude Lagacé, Sheila Vallée
Neonatal jaundice is a frequent condition in newborns and is commonly treated with phototherapy. We describe the case of a neonate with hemolytic disease of the newborn who developed a rarely described purpuric eruption. Laboratory testing revealed elevated porphyrins.
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Eruptive syringomas associated with milia-like idiopathic calcinosis cutis Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-11 Alvaro March-Rodriguez, Rebeca Alcalá, Ramon M. Pujol
An 11-year-old boy presented generalized eruptive syringomas (ESs) associated with multiple milia-like whitish palmar papules corresponding to dermal calcium deposits. A relationship between calcium deposits distribution to an underlying eccrine duct was noted on pathology. The observation of dermal calcium deposits and its association with generalized ESs may support a possible sweat duct origin of
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Hypopigmented papules in a toddler Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-11 Holly A. FitzGerald, Angela Mei, Janet Kim, Nima Mesbah Ardakani, Rachael S. Foster
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest.
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Penile edema in a child Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-11 Maria J. Etcheverry, Sarah H. Millan, Michael H. Hsieh, Michael A. Cardis
CASE PRESENTATION A 7-year-old male presented for gradually worsening, asymptomatic swelling of the penis over a 6-month period. The review of systems was unremarkable, including systemic, gastrointestinal, urinary, or respiratory symptoms. There were no notable fluctuations in the degree of edema on a day-to-day basis. There were no antecedent infections or trauma, and family history was unremarkable
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The sternoclavicular ganglion cyst, a rare pediatric diagnosis Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-12 Thomas Saliba, Gervais Kogni Fokou, Paolo Simoni
We briefly describe the case of a 4-year-old girl, referred for imaging of a small, firm, round, skin-colored, subcutaneous nodule that suddenly appeared at her right sternoclavicular junction. A plain radiograph was non-contributory, but ultrasonography revealed a small cystic structure, leading to the diagnosis of a sternoclavicular ganglion cyst. Sternoclavicular ganglion cysts are a rare diagnosis
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Anaplastic lymphoma kinase-positive histiocytosis with multisystem involvement: A case report Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-12 Yaojun Tu, Yao Lu
Anaplastic lymphoma kinase (ALK)-positive histiocytosis is a rare disease that usually occurs in infants and young children and is characterized by ALK-positive histiocytes infiltrating organs. We present a case of multisystem involvement of ALK-positive histiocytosis in a female infant with skin nodules as the initial presentation. Despite multiorgan involvement, most tumors had spontaneously regressed
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Bleach suit for atopic dermatitis Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-12 Manish K. Shah, Ajit Barve, Resham Vasani, Rajesh Jadhav, Preeti Sheth, Deepak Parikh
Bleach baths are an important adjunct in the management of atopic dermatitis. However, many homes do not have bath tubs. We tried to overcome this by soaking a cotton pajama suit or Indian kurta pajama in dilute bleach solution and then having the child wear it for ten minutes. This is done two to three times a week, as in standard bleach tub baths. We have tried this technique in eleven patients with
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An analysis of information about infantile hemangiomas on TikTok: A cross-sectional study Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-11 Sonora Yun, Maria C. Garzon, Kimberly D. Morel
The video app TikTok, a controversial platform, has increasingly been utilized for the dissemination of health-related topics. In this study, the quality of information on the top 50 most viewed TikTok videos on infantile hemangiomas (IHs) labeled #hemangioma was analyzed. The results showed that the videos were skewed toward more severe subtypes of IH, and most were directed at raising awareness about
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Management of tinea capitis in infants and children in the United States: A national survey of pediatric dermatologists Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-11 Lily Guo, Jacqueline Tran, Dingyuan Iris Sun, Jazmin Starr Newton, Nina M. D'Amiano, Jonathan Lai, Bernard Cohen
This study aimed to evaluate the current management of tinea capitis in the United States, specifically focusing on patients aged 0–2 months, 2 months to 2 years, and 2 years to 18 years. An online survey, distributed through the Pediatric Dermatology Research Alliance and the Society of Pediatric Dermatology, revealed the following preferences: fluconazole for those under 2 months, griseofulvin for
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Frequency of the prominent transverse nasal root vein in children Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-08 Igor López-Carrera, Joseph M. Lam, Antonio Torrelo
The presence of a vascular, blue linear discoloration on the nasal root of infants and young children is a frequent incidental feature, rarely reported in the medical literature. It is related to the trajectory of the transverse nasal root vein (TNRV).
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Abstracts from the 2023 PeDRA Annual Conference Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-05
1 Impact of bariatric surgery on pediatric hidradenitis suppurativa Grace Okpali, BS1, Colleen Cotton, MD2 1Rush Medical College, 2Childrens National Medical Center Hidradenitis Suppurativa (HS) is a chronic inflammatory skin condition characterized by painful recurrent skin lesions. Intertriginous areas such as the axilla, inguinal, and submammary folds are common locations for HS Inflammatory lesions
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COVID-19 infection and vaccination in 92 pediatric patients with cutaneous mastocytosis: A retrospective, cross-sectional study Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-02 Pablo López Sanz, Claudia Guerrero Ramírez, Silvia Manso Córdoba, María Encarnación Alfaro Martínez, Alicia Bascuñana Mendoza, María Encarnación Gómez Sánchez, María Luisa Martínez Martínez, José Manuel Azaña Defez
Mast cells (MCs) can release a variety of biologically active mediators under different circumstances, such as fever or vaccination. Our aim was to evaluate the incidence and severity of MC activation symptoms induced by SARS-CoV-2 virus (COVID-19) infection and vaccination in a cohort of 92 pediatric patients with cutaneous mastocytosis. Our findings support previous evidence on the safety of COVID-19
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A child with Winchester syndrome responding to oral betamethasone and methotrexate Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-01-30 Gaurav Dash, Swetalina Pradhan, Upasna Sinha, Ruchi Sinha
Winchester syndrome (WS) is a rare genetic disorder with a handful of cases reported to date. We report a 14-year-old male who presented with growth retardation, contracture of left lower limb due to thick indurated skin, hypertrichosis, and bilateral corneal opacity. There was complete improvement in joint contracture with oral betamethasone pulse and weekly oral methotrexate.
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Infantile anogenital digitate keratoses Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-01 Sophie-Anne Savard, Julie Powell, Danielle Marcoux, Jérôme Coulombe
Infantile anogenital digitate keratoses (IADK) represent a distinct and under-recognized pediatric condition of the perianal area of infants, significantly more frequent in males than females. The average age of onset is 3.2 months, and it is self-remitting by 2 years of age. Perianal spiny keratoses resistant to usual topical therapies are the hallmark of IADK. We present a series of three cases of
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Effectiveness of dupilumab in pediatric patients with a nummular phenotype of atopic dermatitis Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-01 Eun Jae Kim, Madeline Hlobik, Tina Ho
The nummular phenotype of atopic dermatitis is clinically characterized by pruritic, coin-shaped plaques that are frequently recalcitrant to treatment. In this study, a retrospective chart review was conducted to evaluate the effectiveness and safety of dupilumab in children with nummular lesions of dermatitis. Twelve out of 14 patients demonstrated significant clinical improvement at a median time
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A case series of live attenuated vaccine administration in dupilumab-treated children with atopic dermatitis Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-02 Elaine C. Siegfried, Lara Wine Lee, Jonathan M. Spergel, Randy Prescilla, Sumeet Uppal, Anna Coleman, Ashish Bansal, Sonya L. Cyr, Brad Shumel
Current regulatory labeling recommends avoiding live vaccine use in dupilumab-treated patients. Clinical data are not available to support more specific guidance for live or live attenuated vaccines administration in dupilumab-treated patients.
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Novel multispectral imaging to predict disease progression in pediatric morphea Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-02-02 Cathal O'Connor, Siobhan McCarthy, Lisa Kiely, Michael A. P. McAuliffe, Mary Bennett
Morphea, or localized scleroderma, is an inflammatory, fibrosing skin disorder that can be progressive and debilitating. Infrared thermography frequently has false positive results. The aim of this study was to assess the ability of multispectral imaging to predict disease progression in children with morphea.
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What are keloids? Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-01-29
Keloids are scars that can grow to become very thick. Keloids can become much bigger than the original cut or injury that caused the scar. They can itch and feel harder than regular scars. Keloids can be pink, red, dark brown, or match your own skin color.
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¿Qué es un queloide? Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-01-29
Los queloides son cicatrices que pueden tornarse muy gruesas. Los queloides pueden hacerse más grandes que el corte o lesión original que causó la cicatriz. Estos pueden causar picazón y sentirse más duras que las cicatrices normales. Los queloides pueden ser rosados, rojos, marrón oscuro o ser del mismo color de tu propia piel.
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Topical trametinib for epidermal and sebaceous nevi in a child with Schimmelpenning-Feuerstein-Mims syndrome Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-01-25 Courtney N. Haller, Maria A. Leszczynska, Lars Brichta, Esther Maier, Ian M. Riddington, Keith A. Choate, Moise L. Levy
We present the case of a 20-month-old girl with Schimmelpenning-Feuerstein-Mims (SFM) syndrome with extensive head, neck, and torso skin involvement successfully managed with topical trametinib. Trametinib interferes downstream of KRAS and HRAS in the MAPK signaling pathway, of which KRAS was implicated in our child's pathogenic variant. Although other dermatologic conditions have shown benefit from
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Sudden onset of pigmented spots on the soles Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-01-22 Geethanjali Sahadevan, Amoolya Manalil Trikkovil, Meriya Zacharia, Ajithkumar Kidangazhiyathmana
CONFLICT OF INTEREST STATEMENT All the authors have declared that they have no conflicts of interest.
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A solitary scalp mass as the presenting feature of clear cell sarcoma of the kidney in a pediatric patient Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-01-20 Micah G. Pascual, Anna L. Bruckner, Carla Torres-Zegarra
Clear cell sarcoma of the kidney is a rare renal malignancy, accounting for 2%–4% of all pediatric renal tumors. In this case report, we describe a 9-year-old boy with an asymptomatic, solitary mass on the scalp, ultimately found to be metastatic clear cell sarcoma of the kidney. This report reviews indications for imaging scalp masses to facilitate making an accurate diagnosis and treatment planning
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An updated review on the safety of N, N-diethyl-meta-toluamide insect repellent use in children and the efficacy of natural alternatives Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-01-19 Helana Ghali, Sharon E. Albers
N, N-diethyl-meta-toluamide (DEET) has been considered the ‘gold standard’ for insect repellent use since the 1950s and constitutes most insect repellents on the market. However, conflicting data in the scientific literature and confusing information in the media are at the core of debates about the safety of DEET insect repellents for the protection of children against arthropod bites. The few fatal
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Rapid recovery in a child with febrile ulceronecrotic Mucha-Habermann disease following intravenous immunoglobulin administration Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-01-17 Arun Somasundaram, Ankan Gupta, Dharshini Sathishkumar, Lydia Mathew, Anju George, Meera Thomas
Febrile ulceronecrotic Mucha-Habermann disease (FUMHD), a lymphocyte-mediated inflammatory skin disorder, is considered a severe variant of pityriasis lichenoides et varioliformis acuta that can lead to a fatal outcome if not managed in a timely fashion. Children with FUMHD can have systemic complications involving various organs. The scarcity of reported cases and the absence of well-designed studies
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Cold urticaria as a complication of cryotherapy in the treatment of viral warts Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-01-17 Mayra A. Reyes-Soto, Alejandra Perales-González, Iván Alejandro Rivera-Alonso, Ana Laura Yee-De León, Jorge Ocampo-Candiani, Fania Zamantta Muñoz-Garza
Cryotherapy with liquid nitrogen has been established as the first-line treatment for pediatric patients with viral warts. Cold-induced urticaria (CU) is a rare skin reaction triggered by cold stimuli. We present the case of a pediatric patient with viral warts who developed CU after receiving cryotherapy.
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Incomplete Kawasaki disease presenting with a cellulitis-like plaque: Lessons from an unusual presentation Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-01-19 Sara Banbury, Kirubel Gebre, David M. Milgraum, Ngan Do, Albert C. Yan
Kawasaki disease (KD) is an acute small to medium-vessel vasculitis that primarily affects children under the age of 5 years. The cause of KD is unknown, but it is hypothesized to be a systemic inflammatory illness triggered by infections in genetically predisposed individuals. Diagnosis of incomplete KD is made in patients with prolonged fever without a source who do not meet diagnostic criteria but
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Pediatric consultative dermatology: A survey of the Society for Pediatric Dermatology workforce reveals shortcomings in existing practice models of pediatric dermatology consult services in the United States Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-01-18 Juliana L. Pineider, Sneha A. Rangu, Katharina S. Shaw, Sarah D. Cipriano, Vikash S. Oza
The rate of pediatric hospitalization for cutaneous pathology has been increasing in recent years, often requiring the expertise of consulting pediatric dermatologists; however, the infrastructure of inpatient pediatric dermatology consultative services remains poorly characterized. We sought to assess the structure, consult volume, physician compensation, and utilization of teledermatology in pediatric
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In-person validation of the Ichthyosis Scoring System Pediatr. Dermatol. (IF 1.5) Pub Date : 2024-01-17 Caroline Echeandia-Francis, Qisi Sun, Sarah Asch, Cheryl Bayart, Latanya Benjamin, Sarah D. Cipriano, Brittany Craiglow, Jonathan Dyer, Moise L. Levy, Evelyn Lilly, Brandon Newell, Jingchen Liang, Geliang Gan, Yanhong Deng, Amy S. Paller, Keith A. Choate
Ichthyoses are a heterogeneous group of skin disorders characterized by scaling and erythema. Recognizing the variability of scale and erythema by region and ichthyosis subtype, we developed the Ichthyosis Scoring System (ISS) to quantify severity. We previously found ISS to have high inter- and intrarater reliability in evaluating photographic images. To confirm ISS clinical utility, we examined its