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Rare Cases of Pseudomonas aeruginosa Meningitis in Children: 10-Year Experience in a Single Center J. Child Neurol. (IF 1.9) Pub Date : 2024-03-15 Lijun Liu, Lvchang Zhu, Chanchan Hu, Shuzhen Zhu, Sheng Ye
ObjectiveThe primary objective was to elucidate the epidemiologic characteristics, risk determinants, and clinical outcomes associated with Pseudomonas aeruginosa–induced meningitis.MethodsAll cases of meningitis caused by Pseudomonas aeruginosa that were treated at the hospital between 2012 and 2022 were retrospectively analyzed and detailed.ResultsDuring a 10-year period, only 10 patients satisfied
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Pediatric Subacute Sclerosing Panencephalitis: A Narrative Review on Measles and the Future of Vaccination J. Child Neurol. (IF 1.9) Pub Date : 2024-03-13 Samia Aziz Sulaiman, Nilofar M. Vora, Kusumita Chhabra, Muhammad Arsalan Bashir, Zainab Awan
Subacute sclerosing panencephalitis is a rare complication due to persistent measles infection, characterized by cognitive and motor deterioration. Because subacute sclerosing panencephalitis is considered a potentially fatal complication of measles and usually presents in young populations, particularly those with measles infection under the age of 2 years, new approaches to implement vaccination
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Opening Pressure and Post–Lumbar Puncture Headache in Children Undergoing Intrathecal Baclofen Trial J. Child Neurol. (IF 1.9) Pub Date : 2024-02-29 Amanda E. Summers, Jenny L. Wilson
Aims: Post–lumbar puncture headache occurs in 5% to 12% of children. The purpose of this study was to determine the frequency and predictors of post–lumbar puncture headache in children with hypertonia undergoing lumbar puncture for intrathecal baclofen trial. Methods: This was a retrospective single-center review of all 43 children (<18 years) with hypertonia and/or dyskinesia undergoing intrathecal
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Stereotactic Awake Basal Ganglia Electrophysiological Recording and Stimulation (SABERS): A Novel Staged Procedure for Personalized Targeting of Deep Brain Stimulation in Pediatric Movement and Neuropsychiatric Disorders J. Child Neurol. (IF 1.9) Pub Date : 2024-02-27 Mark A. Liker, Terence D. Sanger, Jennifer A. MacLean, Jaya Nataraj, Enrique Arguelles, Mark Krieger, Aaron Robison, Joffre Olaya
Selection of targets for deep brain stimulation (DBS) has been based on clinical experience, but inconsistent and unpredictable outcomes have limited its use in patients with heterogeneous or rare disorders. In this large case series, a novel staged procedure for neurophysiological assessment from 8 to 12 temporary depth electrodes is used to select targets for neuromodulation that are tailored to
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The Use of Botulinum Toxin Type A in Medically Refractory Pediatric Patients With Chronic Daily Headaches and Its Impact on the Quality of Life J. Child Neurol. (IF 1.9) Pub Date : 2024-02-14 Asra Akbar, Jenna Ford, Sandeep Tripathi
Background: Chronic migraine in children has been a challenging condition to treat, prompting the investigation of alternative therapies. This retrospective single-center chart review aimed to evaluate the efficacy and safety of Botox injections for managing chronic migraine in children. Methods: The study included children with chronic daily headaches and chronic migraine who were medically refractory
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Ketogenic Diet: Parental Experiences and Expectations J. Child Neurol. (IF 1.9) Pub Date : 2024-02-05 Elizabeth Orr, Robyn Whitney, Nandini Nandeesha, Eric H. Kossoff, Rajesh RamachandranNair
BackgroundThe ketogenic diet may be difficult for some patients and their families to implement and can impact physical, emotional, and social well-being.MethodsThrough principles of fundamental qualitative description, we completed an exploratory study on parents’ experiences and expectations on the use and efficacy of the ketogenic diet for children with medically refractory epilepsy.ResultsSeventeen
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Cow's Milk Anemia in Childhood Manifesting as Severe Cerebral Venous Sinus Thrombosis J. Child Neurol. (IF 1.9) Pub Date : 2024-01-24 Kristin Maher, Catherine Amlie-Lefond
We describe a series of 7 toddler-aged children with iron deficiency anemia from excessive cow's milk consumption who presented with cerebral venous sinus thrombosis and no other identifiable risk factors for thrombosis. The deep venous system was involved in 6 patients, 6 had venous infarcts, and 5 have significant neurocognitive sequelae.
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Audio or Video? Access to Pediatric Neurology Outpatient Services Varies by the Type of Telehealth, Especially for Black Children J. Child Neurol. (IF 1.9) Pub Date : 2023-05-15 Annette Grefe, Shyh-Huei Chen, Edward H. Ip, Eric Kirkendall, Savithri Nageswaran
BackgroundChildren of minority race/ethnicity face barriers to accessing specialty services. During the COVID pandemic, health insurance companies reimbursed telehealth services. Our objective was ...
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Meaningful Improvements in Rett Syndrome: A Qualitative Study of Caregivers J. Child Neurol. (IF 1.9) Pub Date : 2023-05-09 Sarah A. McGraw, Constance Smith-Hicks, James Nutter, Jeffrey C. Henne, Victor Abler
BackgroundRett syndrome is a rare neurodevelopmental disorder primarily affecting females. This syndrome is associated with many comorbidities and impairments related to motor function, breathing, ...
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Adolescent Gender Differences in Tic- and Non-Tic-Related Impairments in Tourette Syndrome J. Child Neurol. (IF 1.9) Pub Date : 2023-05-08 Travis R. Larsh, Steve W. Wu, David A. Huddleston, Sean White, Tara D. Lipps, Donald L. Gilbert
We aimed to compare tic- and non-tic-related impairment experienced by adolescent girls and boys (ages 13 through 17) with Tourette syndrome and associations with age. We extracted from the electro...
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Development and Evaluation of a Child Neurology Resident Curriculum for Communication Around Serious Illness J. Child Neurol. (IF 1.9) Pub Date : 2023-05-08 Jan A. Martin, Fiona Sampey, Alison Feldman, Lori Silveira, Craig A. Press, Ricka Messer, Megan Barry, Paritosh Kaul
Background: Communication around serious illness is a core competency for all residencies. One-fifth of neurology residencies have no curriculum. Published curricula use didactics or role-play to a...
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Exploring the Age-Old Question: What Is the Predictive Value of EEG for Future Epilepsy in Children With Complex Febrile Seizures? J. Child Neurol. (IF 1.9) Pub Date : 2023-05-07 Purva R. Choudhari, Andrea Lowden, Alison Dolce
Children with complex febrile seizures (CFS) have increased risk for the development of epilepsy, but varying prognostic value has been ascribed to abnormal post-CFS electroencephalograms (EEGs). W...
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The Spectrum of Pediatric Infection-Associated Intracranial Arteriopathies and Acute Ischemic Stroke at 2 Eastern Indian Tertiary Care Centres J. Child Neurol. (IF 1.9) Pub Date : 2023-05-03 Suman Das, Biman Kanti Ray, Lopamudra Mishra, Kaushani Chatterjee, Gobinda Mondal, Dilip Kumar Paul
IntroductionMajor and minor pediatric infections may cause intracranial arteriopathies, the long-term outcome of which we investigated and identified the factors influencing the progression/resolut...
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Language and Cognitive Outcomes Following Ischemic Stroke in Children With Monolingual and Bilingual Exposure J. Child Neurol. (IF 1.9) Pub Date : 2023-05-03 Kai Ian Leung, Nomazulu Dlamini, Robyn Westmacott, Monika Molnar
AimAlthough many children who experience ischemic stroke come from bilingual backgrounds, it is unclear whether bilingual exposure affects poststroke development. Our research evaluates bilingual a...
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Use of Thalamus L-Sign to Differentiate Periventricular Leukomalacia From Neurometabolic Disorders J. Child Neurol. (IF 1.9) Pub Date : 2023-05-02 Sabahattin Yuzkan, Merve Emecen Sanli, Merve Balci, Pakize Cennetoglu, Ihsan Kafadar, Burak Kocak
PurposeTo assess the diagnostic value of the thalamus L-sign on magnetic resonance imaging (MRI) in distinguishing between periventricular leukomalacia and neurometabolic disorders in pediatric pat...
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Use of Invasive Brain-Computer Interfaces in Pediatric Neurosurgery: Technical and Ethical Considerations J. Child Neurol. (IF 1.9) Pub Date : 2023-04-28 David Bergeron, Christian Iorio-Morin, Marco Bonizzato, Guillaume Lajoie, Nathalie Orr Gaucher, Éric Racine, Alexander G. Weil
Invasive brain-computer interfaces hold promise to alleviate disabilities in individuals with neurologic injury, with fully implantable brain-computer interface systems expected to reach the clinic...
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Anemia and Poor Iron Indices Are Associated With Susceptibility to Febrile Seizures in Children: A Systematic Review and Meta-analysis J. Child Neurol. (IF 1.9) Pub Date : 2023-04-26 Rini Sulviani, William Kamarullah, Sherly Dermawan, Helen Susanto
IntroductionFebrile seizures are the most common type of seizure in children under the age of 5, and a number of risk factors for this condition have been identified. Several studies have examined ...
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A National, Electronic Health Record–Based Study of Perinatal Hemorrhagic and Ischemic Stroke J. Child Neurol. (IF 1.9) Pub Date : 2023-04-25 Stuart Fraser, Samantha M. Levy, Yashar Talebi, Sean I. Savitz, Alicia Zha, Gen Zhu, Hulin Wu
BackgroundPerinatal stroke occurs in approximately 1 in 1100 live births. Large electronic health record (EHR) data can provide information on exposures associated with perinatal stroke in a larger...
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Sleep Problems After Concussion Are Associated With Poor Balance and Persistent Postconcussion Symptoms J. Child Neurol. (IF 1.9) Pub Date : 2023-04-25 Samantha N. Magliato, Mathew J. Wingerson, Corrine N. Seehusen, Katherine L. Smulligan, Stacey L. Simon, Julie C. Wilson, David R. Howell
We examined the association of self-reported sleep problems with clinical measures of postural stability, memory performance, symptom burden, and symptom duration following youth concussion. Patien...
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Socioeconomic, Clinical, and Laboratory Parameters Differentiating Pediatric Patients With MOG Antibody–Associated Disease and Multiple Sclerosis J. Child Neurol. (IF 1.9) Pub Date : 2023-04-25 Brian Florenzo, J. Nicholas Brenton
Studies indicate differences in the clinical phenotypes and neuroimaging of children with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) compared to multiple sclerosis; how...
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Cognitive Behavioral Therapy for Children With Headaches: Will an App Do the Trick? J. Child Neurol. (IF 1.9) Pub Date : 2023-04-25 Carinna Moyes, Reza Belaghi, Richard J. Webster, Nicole Whitley, Daniela Pohl
Participants were enrolled into a pilot randomized-controlled 4-week trial comparing the efficacy and feasibility of app-based cognitive behavioral therapy (CBT) to a stretching program. Headache-r...
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Neuroimaging Findings in Vitamin B12-Deficient Infants With Neurologic Features J. Child Neurol. (IF 1.9) Pub Date : 2023-04-24 Anjali Yadav, Chandrika Azad, Ravinder Kaur, Vishal Guglani, Seema Gupta, Sukanya Mitra
Background:Vitamin B12 deficiency causes serious neurologic problems among infants. However, its neuroradiologic correlate is still largely obscure. Methodology: This prospective study was conducte...
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Diagnostics Value of Quantitative Magnetic Resonance Imaging (MRI) in Neonatal Acute Bilirubin Encephalopathy J. Child Neurol. (IF 1.9) Pub Date : 2023-04-16 Hua Liu, Ruolin Zhang, Min Zhang, Huanji Zheng, Xiuxiu Li, Jun Chen
Background: This study was designed to investigate the diagnostic value of relative signal intensity of globus pallidus on T1-weighted magnetic resonance imaging (MRI) in neonatal acute bilirubin e...
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Odds of Cardiometabolic Diseases and Medications in Children With Cerebral Palsy J. Child Neurol. (IF 1.9) Pub Date : 2023-04-05 Rachel Dum, Vonn Walter, Neal J. Thomas, Conrad Krawiec
Introduction/ObjectivesIndividuals with cerebral palsy may be at risk of obesity, but outcomes and risk factors are understudied. The study objectives are to evaluate the frequency of body mass ind...
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A Standardized, 3-Tiered, Seizure Burden–Based Protocol for the Treatment of Neonatal Seizures J. Child Neurol. (IF 1.9) Pub Date : 2023-04-04 Ashley A. Moeller, Andrei R. Stefanescu, Beatrice M. Stefanescu, Meredith R. Golomb, Frances A. Boyle, William F. Buss, Rebecca S. Rose, Sarah E. Wing
ObjectiveTo evaluate use of a standardized, 3-tiered, seizure burden-based protocol for treatment of all electroencephalography (EEG)-confirmed seizures in a level IV neonatal intensive care unit (...
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A Multidisciplinary Pediatric Neurology Clinic for Systematic Follow-up of Children with Neurologic Sequelae of COVID-19 J. Child Neurol. (IF 1.9) Pub Date : 2023-03-29 Payal B. Patel, Kristina E. Patrick, Giulia M. Benedetti, Lindsey A. Morgan, Katherine S. Bowen, Jason N. Wright, Mark S. Wainwright
Clinical guidance on outpatient follow-up of children hospitalized with acute neurologic complications of SARS-CoV2 infection is needed. We describe the clinical infrastructure of our pediatric neu...
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Tolerability and Safety of Lacosamide in Neonatal Population J. Child Neurol. (IF 1.9) Pub Date : 2023-03-27 Olajumoke Bamgbose, Frances Boyle, Adam C. Kean, Beatrice M. Stefanescu, Sarah Wing
Lacosamide is a newer antiepileptic medication used in refractory neonatal seizures with limited safety and efficacy data. This case series spans 4 years and includes 38 neonates cared for in the n...
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Characteristics of Children With Cerebral Palsy in the Post–Therapeutic Hypothermia Era J. Child Neurol. (IF 1.9) Pub Date : 2023-03-05 Heather Pekeles, Fatema Al Amrani, Marta Perez-Morgui, Pia Wintermark, Michael Shevell
Objectives: To explore the profile of children with cerebral palsy secondary to intrapartum asphyxia treated with therapeutic hypothermia after birth and to compare characteristics of children trea...
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Approach to New-Onset Psychosis in Pediatrics: A Review of Current Practice and an Interdisciplinary Consensus-Driven Clinical Pathway at a Single-Center Institution J. Child Neurol. (IF 1.9) Pub Date : 2023-02-21 Alexander Jonokuchi, Daniel Fenster, Teresa McCann, Maalobeeka Gangopadhyay, Mirna Giordano, Alexis Maddocks, Mina Ekladios, Colleen Turek, Megan Mroczkowski, Nazreen Jamal, Wendy Vargas
New-onset psychosis in the pediatric population poses many diagnostic challenges. Given the diversity of underlying causes, which fall under the purview of multiple medical specialties, a timely, t...
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The Epilepsy Surgery Experience in Children With Infantile Epileptic Spasms Syndrome at a Tertiary Care Center in Canada J. Child Neurol. (IF 1.9) Pub Date : 2023-02-14 Jennifer V. Gettings, Shatha Shafi, Jennifer Boyd, O. Carter Snead, James Rutka, James Drake, Bláthnaid McCoy, Puneet Jain, Robyn Whitney, Cristina Go
BackgroundInfantile epileptic spasms syndrome is an epileptic encephalopathy, characterized by spasms, hypsarrhythmia, and developmental regression. Appropriately selected patients with infantile e...
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Pelizaeus-Merzbacher Disease: A Caregiver Assessment of Disease Impact J. Child Neurol. (IF 1.9) Pub Date : 2023-02-06 Katrina M Moore, Nicole I. Wolf, Grace Hobson, Kristina Bowyer, Jordan McSherry, Gail Hartin, Claire Wilde, Stacey Shapiro, Jason Frank, David Manley, Candice Junge
Pelizaeus-Merzbacher disease is a rare X-linked leukodystrophy accompanied by central nervous system hypomyelination with a spectrum of clinical phenotypes. This is the first survey of caregivers o...
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Agreement Between House-Brackmann and Sunnybrook Facial Nerve Grading Systems in Bell's Palsy in Children: Secondary Analysis of a Randomized, Placebo-Controlled Multicenter Trial J. Child Neurol. (IF 1.9) Pub Date : 2023-02-05 Amanda Williams, Nitaa Eapen, Amit Kochar, Ben Lawton, Jason Hort, Adam West, Shane George, Robert Berkowitz, Katherine J Lee, Stuart R Dalziel, Stephen Hearps, Franz E Babl, on behalf of the PREDICT (Paediatric Research in Emergency Departments International Collaborative) research network
BackgroundThere is limited evidence on the use of facial nerve function grading scales in acute facial nerve paralysis in children.ObjectiveTo investigate the agreement between and the usability of...
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Leber Mitochondrial Optic Neuropathy in Pediatric Females With Focus on Very Early Onset Cases J. Child Neurol. (IF 1.9) Pub Date : 2023-01-19 Sara Tagliani, Cristina Malaventura, Chiara Ceccato, Francesco Parmeggiani, Agnese Suppiej
The aim of this study was to describe the phenotype of Leber hereditary optic neuropathy occurring in pediatric females. This disease generally affects young adult males, but it can occur also in f...
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Identifying Genetic Susceptibility in Neonates With Hypoxic-Ischemic Encephalopathy: A Retrospective Case Series J. Child Neurol. (IF 1.9) Pub Date : 2023-01-10 Kristine E. Woodward, Prashanth Murthy, Aleksandra Mineyko, Khorshid Mohammad, Michael J. Esser
Neonatal hypoxic-ischemic encephalopathy is a clinical phenomenon that often results from perinatal asphyxia. To mitigate secondary neurologic injury, prompt initial assessment and diagnosis is nee...
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Causes of HyperCKemia in Children: A Retrospective Cohort Study J. Child Neurol. (IF 1.9) Pub Date : 2022-12-25 Damaris Pasca, Matthew Ginsberg
Background and Objectives: Creatine kinase (CK) is a commonly used screening test for neuromuscular disorders (NMDs). However, hyperCKemia can result from several pathologic and physiologic causes....
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Imaging Similarities Between Oral-Facial-Digital Syndrome Type 1 and Aicardi Syndrome: Prenatal and Postnatal Magnetic Resonance Imaging (MRI) Findings in 4 Patients J. Child Neurol. (IF 1.9) Pub Date : 2022-12-25 Charu Venkatesan, Elizabeth Countee, Beatrix Wong, Christine Spaeth, Beth M. Kline-Fath, Usha D. Nagaraj
Prenatal identification by magnetic resonance imaging (MRI) of callosal anomalies, particularly with accompanying intracranial abnormalities, poses a challenge for accurate prognostication and feta...
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Association of NOD1 and NOD2 Polymorphisms With Susceptibility to Subacute Sclerosing Panencephalitis J. Child Neurol. (IF 1.9) Pub Date : 2022-12-21 Ayça Kocaaga, Gunes Cakmak Genc, Sevim Karakas Celik, İbrahim E. Piskin, Mustafa Calik, Ahmet Dursun
Background: Subacute sclerosing panencephalitis is a progressive neurodegenerative disease that is a late complication of measles infection. However, to date, the pathogenesis of subacute sclerosin...
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Disease Burden in Children With Spinal Muscular Atrophy: Results From a Large Cross-Sectional Study J. Child Neurol. (IF 1.9) Pub Date : 2022-12-19 Spencer Rosero, Jennifer Weinstein, Jamison Seabury, Christine Zizzi, Ellen Wagner, Anika Varma, John Heatwole, Danae Alexandrou, Nuran Dilek MS, Brent A. Johnson, Chad Heatwole
Background:To facilitate advances in spinal muscular atrophy therapeutic research, it is important to determine the impact and prevalence of symptoms experienced by children with spinal muscular at...
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Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET)/Computed Tomography Features of Atypical Teratoid/Rhabdoid Tumors: Case Series and Review J. Child Neurol. (IF 1.9) Pub Date : 2022-11-23 Xu Kang, Hongping Xia, Loren Skudder-Hill, Yafu Yin, Xiaoqiang Wang
Purpose: The purpose of this article is to explore the clinical and neuroradiologic properties of atypical teratoid/rhabdoid tumors. Methods: Data from 6 pediatric patients with atypical teratoid/r...
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A Scoping Review of Magnetic Resonance Modalities Used in Detection of Persistent Postconcussion Symptoms in Pediatric Populations J. Child Neurol. (IF 1.9) Pub Date : 2022-11-15 Elena Sheldrake, Brendan Lam, Hiba Al-Hakeem, Anne L. Wheeler, Benjamin I. Goldstein, Benjamin T. Dunkley, Stephanie Ameis, Nick Reed, Shannon E. Scratch
Up to 30% of youth with concussion experience PPCSs (PPCS) lasting 4 weeks or longer, and can significantly impact quality of life. Magnetic resonance imaging (MRI) has the potential to increase un...
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Staring Spells: An Age-based Approach Toward Differential Diagnosis J. Child Neurol. (IF 1.9) Pub Date : 2022-11-13 Ajay Goenka, Irma Reyes, Laura D. Fonseca, Monica C. George, Adrienne Stolfi, Gogi Kumar
Evaluations to rule out epileptic vs nonepileptic staring spells may entail unnecessary evaluations that can be costly and time consuming. Our study aims to identify common etiologies for staring s...
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The Prevalence and Clinical Characteristics of Primary Stabbing Headache J. Child Neurol. (IF 1.9) Pub Date : 2022-10-17 Semra Saygi
ObjectiveThis study aimed to determine the prevalence and characteristics of primary stabbing headache in children and adolescents that presented because of headache. Materials and Methods: The med...
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Why Would a Child Have a Stroke? J. Child Neurol. (IF 1.9) Pub Date : 2022-10-09 Laurel Persa, Dennis WW Shaw, Catherine Amlie-Lefond
Identifying the etiology of childhood arterial ischemic stroke helps prevent stroke recurrence. In addition, stroke may herald a serious underlying condition requiring treatment, such as acquired h...
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Greater Acute Concussion Symptoms Are Associated With Longer Recovery Times in Adolescents J. Child Neurol. (IF 1.9) Pub Date : 2022-10-09 Nathan E. Cook, Charles E. Gaudet, Bruce Maxwell, Ross Zafonte, Paul D. Berkner, Grant L. Iverson
We examined the association between the severity of acute concussion symptoms and time to return to school and to sports in adolescent student athletes. We hypothesized that there would be an assoc...
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Surgically Remediable Secondary Network Epileptic Encephalopathies With Continuous Spike Wave in Sleep: Lesions May Not Be Visible on Brain Magnetic Resonance Imaging (MRI) J. Child Neurol. (IF 1.9) Pub Date : 2022-10-03 Abdulla Alawadhi, Juan Pablo Appendino, Walter Hader, Bernard Rosenblatt, Jeremy T. Moreau, Francois Dubeau, Roy W.R. Dudley, Kenneth A. Myers
BackgroundContinuous spike wave in sleep (CSWS) is an electroencephalogram (EEG) pattern associated with developmental and epileptic encephalopathy with spike-and-wave activation in sleep (DEE-SWAS...
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Role of Electroencephalogram (EEG) and Magnetic Resonance Imaging (MRI) Findings in Early Recognition and Diagnosis of Neuronal Ceroid Lipofuscinosis Type 2 Disease J. Child Neurol. (IF 1.9) Pub Date : 2022-10-03 Mai-Lan Ho, Elaine C. Wirrell, Kalliopi Petropoulou, Ai Sakonju, Dorna Chu, Guillermo Seratti, Susan Palasis
Neuronal ceroid lipofuscinosis type 2 (CLN2) disease is a very rare neurodegenerative lysosomal storage disorder. Progression is rapid and irreversible, making early diagnosis crucial for timely tr...
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Overgrowth of the Amygdala in Children with Single Ventricle Congenital Heart Disease J. Child Neurol. (IF 1.9) Pub Date : 2022-09-28 Rie Sato, Jun Muneuchi, Yuichiro Sugitani, Hirohito Doi, Takashi Furuta, Hiroki Ezaki, Masaru Kobayashi, Eriko Hatai, Mamie Watanabe
AimEarly life stress is associated with overgrowth of the amygdala, which plays a key role in the processing and memory of emotional responses. Herein, we aimed to explore the amygdala volume in ch...
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Risk Factors and Imaging Biomarkers Associated With Perioperative Stroke in Pediatric Moyamoya Arteriopathy J. Child Neurol. (IF 1.9) Pub Date : 2022-09-21 Sarah E. Gardner Yelton, John Gatti, Malik Adil, Melike Guryildirim, Aylin Tekes, Lisa R. Sun
Patients with moyamoya arteriopathy are at high risk for developing ischemic stroke in the perioperative period. We sought to evaluate whether preoperative clinical and neuroimaging biomarkers are ...
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Pediatric Status Epilepticus Severity Score (STEPSS): Predictive Performance of Functional Outcomes: A Prospective Single-Center Study J. Child Neurol. (IF 1.9) Pub Date : 2022-09-21 Ekin Soydan, Ahmet Gonullu, Yigit Aksoy, Yigithan Guzin, Gokhan Ceylan, Sevgi Topal, Mustafa Colak, Pınar Hepduman, Ozlem Sarac Sandal, Gulhan Atakul, Utku Karaarslan, Aycan Unalp, Hurşit Apa, Hasan Agın
Objective: To prospectively investigate the predictive value of the modified Status Epilepticus Severity Score (STESS) for pediatric use (STEPSS) regarding unfavorable outcomes in the short term. M...
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Upper Limb Onabotulinumtoxin A Injections in Children Under 2 Years with Cerebral Palsy: A Retrospective Chart Review J. Child Neurol. (IF 1.9) Pub Date : 2022-09-15 Danni Centorame, Barry Rawicki, Sabine Hennel, Brian Hoare
AimTo report on the safety of using Onabotulinumtoxin A (OnaA) in the upper limb(s) of children <2 years of age with cerebral palsy and to describe a proactive clinical model of care in the managem...
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Differences in Cerebellar Volume as a Diagnostic and Prognostic Biomarker in Children and Adolescents With Epilepsy of Unknown Etiology J. Child Neurol. (IF 1.9) Pub Date : 2022-09-15 Katja Glutig, Luisa Lange, Paul-Christian Krüger, Stephanie Gräger, Heike de Vries, Ulrich Brandl, Christian Gaser, Hans-Joachim Mentzel
Introduction and ObjectiveEpilepsy is one of the most common brain diseases during childhood and adolescence. Atrophy in different brain areas is possible during epilepsy. This study aimed to verif...
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Corrigendum J. Child Neurol. (IF 1.9) Pub Date : 2022-09-09
Corrigendum to: Segal E, Moretz K, Wheless J, et al. PROVE—Phase IV Study of Perampanel in Real-World Clinical Care of Patients with Epilepsy: Interim Analysis in Pediatric Patients. Journal of Child Neurology. 2022;37(4):256-267. doi:10.1177/08830738211047665
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Pilot Study of Associations Among Functional Connectivity and Neurocognition in Survivors of Pediatric Brain Tumor and Healthy Peers J. Child Neurol. (IF 1.9) Pub Date : 2022-09-07 Safiyah Seck, Young Jin (Ginnie) Kim, William A. Cunningham, Randal Olshefski, Keith Owen Yeates, Kathryn Vannatta, Kristen R. Hoskinson
This pilot study examined the associations among functional connectivity in the salience, central executive, and default mode networks, and neurocognition in pediatric brain tumor survivors and hea...
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Thalamic Volume Loss Is Greater in Children Than in Adults Following Middle Cerebral Artery Territory Arterial Ischemic Stroke J. Child Neurol. (IF 1.9) Pub Date : 2022-09-07 Emily J. Mastej, Michelle H. Leppert, Sharon Poisson, Zak Ritchey, Megan Barry, Tatjana Rundek, David S. Liebeskind, David Mirsky, Timothy J. Bernard, Nicholas V. Stence
Background: Younger stroke patients may suffer worse outcomes than older patients; however, the extent to which age at stroke impacts remote areas of the brain remains unclear. The objective of thi...
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Deep Brain Stimulation for Pediatric Dystonia: A Review of the Literature and Suggested Programming Algorithm J. Child Neurol. (IF 1.9) Pub Date : 2022-09-02 Rose Gelineau-Morel, Michael C. Kruer, Jordan F. Garris, Amal Abu Libdeh, Daniel A. N. Barbosa, Keith A. Coffman, David Moon, Christopher Barton, Alonso Zea Vera, Adrienne B. Bruce, Travis Larsh, Steve W. Wu, Donald L. Gilbert, Jennifer A. O’Malley
Deep brain stimulation (DBS) is an established intervention for use in pediatric movement disorders, especially dystonia. Although multiple publications have provided guidelines for deep brain stimulation patient selection and programming in adults, there are no evidence-based or consensus statements published for pediatrics. The result is lack of standardized care and underutilization of this effective
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Pediatric Headache Experience During the COVID-19 Pandemic J. Child Neurol. (IF 1.9) Pub Date : 2022-08-24 Marc DiSabella, Emily Pierce, Emily McCracken, Aarane Ratnaseelan, Lauren Vilardo, Kelsey Borner, Raquel Langdon, Angela A. Fletcher
Objective Headache disorders are exceedingly common in children and adolescents. The association between headaches, emotional stress, and disruptions in daily routines are well established. The goal of this study is to compare the experiences of patients with a preexisting diagnosis of a primary headache disorder in terms of headache frequency and severity, lifestyle techniques for headache prevention
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Letter to the editor response J. Child Neurol. (IF 1.9) Pub Date : 2022-08-18 Conrad Krawiec, Katsiah Cadet, Jessica Boegner, Gary D. Ceneviva, Neal J. Thomas
We thank Finsterer et al for offering their insights and interest in our retrospective study, where we identified 44 pediatric subjects who had a diagnostic code of “simple febrile convulsions” (30 [68.2%]) or “complex febrile convulsions” (14 [31.8%]) and an associated COVID-19 diagnostic code. We understand their concerns, and will attempt to address them below.
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In Memoriam: Folker Hanefeld, MD, PhD, June 28, 1937–May 9, 2022 J. Child Neurol. (IF 1.9) Pub Date : 2022-08-08 Alan K. Percy, Jeffrey L. Neul, Dietz Rating
Folker Hanefeld, a founding member of child neurology in Germany, passed away peacefully on May 9, 2022 (Figure 1). Long regarded as instrumental in the development of child neurology, not only in Germany but also in Europe, Folker together with Bengt Hagberg (Sweden), Jean Aicardi (France), John Wilson (United Kingdom), and Edward Brett (United Kingdom), created the early training programs in Europe
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Targeted Whole Exome Sequencing in Children With Early-Onset Epilepsy: Parent Experiences J. Child Neurol. (IF 1.9) Pub Date : 2022-08-03 Armaghan Alam, Maksim Parfyonov, Camille Y. Huang, Inderpal Gill, Mary B. Connolly, Judy Illes
This study investigated the experiences of 25 caregivers of children with early-onset, treatment-resistant epilepsy who pursued whole exome sequencing to determine the impact of the test results on their child’s treatment. Caregivers who consented to be recontacted were recruited from a previous study investigating the diagnostic yield of whole exome sequencing. A semistructured interview addressed