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MRI and pathology comparisons in Rasmussen’s encephalitis: a multi-institutional examination of hemispherotomy outcomes relative to imaging and histological severity Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-15 Alexander Doherty, Kathleen Knudson, Christine Fuller, James L. Leach, Anthony C. Wang, Neena Marupudi, Rowland H. Han, Stuart Tomko, Jeff Ojemann, Matthew D. Smyth, Francesco Mangano, Jesse Skoch
Purpose Rasmussen encephalitis (RE) is a very rare chronic neurological disorder of unilateral inflammation of the cerebral cortex. Hemispherotomy provides the best chance at achieving seizure freedom in RE patients, but with significant risks and variable long-term outcomes. The goal of this study is to utilize our multicenter pediatric cohort to characterize if differences in pathology and/or imaging
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Atlantoaxial facet fixation using cervical facet cage: technical case report and review of the literature Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-14 Sharath Kumar Anand, Regan M. Shanahan, Ali A. Alattar, H. Westley Phillips, David O. Okonkwo, Michael M. McDowell
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Obituary: Professor Dr. Meral Baka (1955–2024) Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-13 Mehmet Turgut, Yiğit Uyanıkgil
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The diagnostic value of MRI findings in pediatric idiopathic intracranial hypertension: a case-control study Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-13
Abstract Background Idiopathic intracranial hypertension (IIH) is a rare medical condition in children. Based on the different radiological findings reported in various studies in pediatric IIH, this study was conducted to determine the diagnostic value of MRI findings in diagnosing IIH in children. Methods In this retrospective study, the medical records of all children aged 1 to 18 years who visited
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Nimotuzumab-vinorelbine combination therapy versus other regimens in the treatment of pediatric diffuse intrinsic pontine glioma Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-13 Ayşe Özkan, Begül Yağcı Küpeli, Serhan Küpeli, Gülay Sezgin, İbrahim Bayram
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Recurrent primary intracranial sarcoma, DICER1-mutant in a pediatric patient with DICER1 syndrome: the importance of molecular testing Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-13 Alexandre Lachance, Evan Dimentberg, Sidong Huang, Samuel Bergeron-Gravel, Éric Bouffet, Adriana Fonseca, Louis Crevier, Stephan Saikali, Catherine Bourget, Panagiota Giannakouros, Damien Faury, Nada Jabado, William D Foulkes, Valérie Larouche, Samuele Renzi
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Spontaneous regression of an epidermoid cyst in a pediatric patient—Case report and review of the literature Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-12 Irina Stavarache, Cecilia Parazzini, Chiara Doneda, Filippo Arrigoni, Stefania Maria Bova, Andrea Righini
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Distinct patterns of postoperative fever in paediatric neurosurgery patients Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-12
Abstract Purpose Postoperative fever is a common problem following neurosurgery but data on the causes among paediatric patients is sparse. In this report, we determined the incidence, causes, and outcomes of postoperative fever in paediatric neurosurgical patients (< 18 years), and contrasted the findings with an adult cohort published recently from our unit. Methods We recruited 61 patients who underwent
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Neurosurgical intervention for the Meckel-Gruber Syndrome: A systematic review Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-09
Abstract Introduction Meckel-Gruber Syndrome (MKS) is an autosomal recessive genetic disorder, notable for its triad of occipital encephalocele, polycystic renal dysplasia, and postaxial polydactyly. Identified by Johann Friederich Meckel in 1822, MKS is categorized as a ciliopathy due to gene mutations. Diagnosis is confirmed by the presence of at least two key features. The condition is incompatible
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Surgical limits, pitfalls, and potential solutions in kyphectomy in myelomeningocele: three cases and systematic review of the literature Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-09 Raffaele De Marco, Luigi Aurelio Nasto, Antonio Strangio, Gianluca Piatelli, Marco Pavanello
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Intracranial complications of sinogenic and otogenic infections in children: an ESPN survey on their occurrence in the pre-COVID and post-COVID era Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-08 L. Massimi, G. Cinalli, P. Frassanito, V. Arcangeli, C. Auer, V. Baro, A. Bartoli, F. Bianchi, S. Dietvorst, F. Di Rocco, P. Gallo, F. Giordano, J. Hinojosa, S. Iglesias, V. Jecko, G. Kahilogullari, F. Knerlich-Lukoschus, R. Laera, D. Locatelli, D. Luglietto, M. Luzi, M. Messing-Jünger, R. Mura, P. Ragazzi, L. Riffaud, J. Roth, A. Sagarribay, M. Santos Pinheiro, P. Spazzapan, P. Spennato, N. Syrmos
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Pediatric fibromyxoid brachial plexus tumor with YWHAZ::PLAG1 gene fusion: a case report Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-08 Sean Kendrich N. Cua, Eugene G. Odoño, Kevin Ivan P. Chan, Dondiego Eleazar G. Casanova, Aileen Guerzon, Kathleen Joy O. Khu
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Peripheral nerve decompression for pain relief in the setting of previous obstetrical brachial plexus injury: a retrospective case series Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-08
Abstract Purpose In children with previous obstetrical brachial plexus injury (OBPI), upper extremity pain is present in 45 to 66% of patients. Recent literature reports this as musculoskeletal or neuropathic in nature. The purpose of the study is to demonstrate that peripheral nerve decompression, and neurolysis may be an effective treatment for patients with upper extremity pain in the context of
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Pediatric neurosurgery training during residency in Switzerland and the need for dedicated subspecialization training Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-08 Ladina Greuter, Maria Licci, Raphael Guzman, Jehuda Soleman
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Giant brainstem cavernoma in pediatrics: diagnosis and treatment—case report Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-07 María Eugenia Badaloni, Javier Danilo Gonzalez Ramos
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Feasibility and safety of stereoelectroencephalography in young children Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-07
Abstract Purpose Stereoelectroencephalography (SEEG) is a diagnostic surgery that implants electrodes to identify areas of epileptic onset in patients with drug-resistant epilepsy (DRE). SEEG is effective in identifying the epileptic zone; however, placement of electrodes in very young children has been considered contraindicated due to skull thinness. The goal of this study was to evaluate if SEEG
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Conservative management for pediatric craniocervical Pott’s disease: A case study and literature review Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-07 Anne-Sophie Parent, Albert Tu
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An unusual finding of an anaplastic meningioma in NF2-related schwannomatosis Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-07 Siegfried J. Adelhoefer, James Feghali, Sharika Rajan, Charles G. Eberhart, Verena Staedtke, Alan R. Cohen
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Incidence of tethered cord syndrome in neurofibromatosis types 1 and 2 pediatric patients: a population-level analysis Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-07
Abstract Purpose Tethered spinal cord syndrome (TCS) is characterized by cutaneous attachments on the filum terminale that stretch the spinal cord, leading to musculoskeletal and urogenital sequelae. While the neurocutaneous associations with TCS remain undefined, a recent study reports a high incidence of TCS among a pediatric neurofibromatosis (NF) cohort. This present study utilizes a population-level
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Association of spinal cord abnormalities with vertebral anomalies: an embryological perspective Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-05 Olga M. Sergeenko, Dmitry M. Savin, Konstantin A. Diachkov
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Image-guided biopsy of intracranial lesions in children, with a small robotic device: a case series Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-05 Pietro Spennato, Marianna Di Costanzo, Giuseppe Mirone, Domenico Cicala, Lucia De Martino, Nicola Onorini, Claudio Ruggiero, Giuseppe Cinalli
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Comparative study between ventriculosubgaleal shunt and external ventricular drain for management of post infective hydrocephalus among pediatrics Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-05 Abdelaziz Abdelhamid Ismail, Ahmed Nageeb Taha, Hatem Ibraheem Badr, Ahmed Zaher, Samy Abbas Elbaz, Amr Farid Khalil
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Simultaneous spine extradural and intradural teratomas in a pediatric patient: A rare presentation with insights in the flawed migration of germ cells theory Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-02
Abstract Spinal teratomas are infrequent lesions in the pediatric population. These lesions can be extradural, intradural or intramedullary. We present a case of an 8-month-old boy that was assessed for underdevelopment of motor milestones. The neurologic examination revealed hyporeflexia, decreased sensation and flaccid paraplegia. MRI of the spine revealed two simultaneous and independent lesions
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“The blue catheter” - case report Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-01 J.V.F. Lima, M.D.S. da Costa, S. Cavalheiro
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3D printing in pediatric neurosurgery: experimental study of a novel approach using biodegradable materials Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-03-01 Roni Mai, Vladimir Popov, Ekaterina Mishina, Egor Osidak
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The prepontine block and its relevance for the development and treatment of hydrocephalus Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-20 Carla Richetta, Shelly I. Shiran, Shlomi Constantini, Jonathan Roth
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Brain stem tumors in children less than 3 months: Clinical and radiologic findings of a rare disease Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-20 Danai Papangelopoulou, Brigitte Bison, Lars Behrens, Simon Bailey, Marc Ansari, Karoline Ehlert, Ofelia Cruz Martinez, Christof M. Kramm, Andres Morales La Madrid, Andre O. von Bueren
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Neurological outcome following delayed traction and fixation in severe tetraparesis consecutive to posterior decompression for Chiari malformation: a case report Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-19 Eric Vigneul, Nicole Del Gaudio, Loïc de Nijs, Christian Raftopoulos
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Pulsatile giant sacrococcygeal teratoma appearing like 2nd head Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-19 Abhijit Acharya, A. K. Mahapatra, Souvagya Panigrahi, Ram Chandra Deo, Satya Bhusan Senapati
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Successful surgical treatment of oculomotor palsy due to schwannoma of the cavernous sinus in a 7-year-old girl: a case report Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-19 Noboru Ishino, Kenichi Ishibashi, Noritsugu Kunihiro, Kazuhiro Yamanaka, Takeshi Inoue, Takeo Goto
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Predictors of neurocognition outcomes in children and young people with primary brain tumor presenting to tertiary care hospitals of Karachi, Pakistan: a prospective cohort study Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-16
Abstract Introduction Primary brain tumors are a common cause of morbidity and mortality in children and young people (CYP) globally. Impaired neurocognitive function is a potential severe consequence in primary brain tumor (PBT) survivors. There are no in-depth studies from low- and middle-income countries (LMICs) to inform management and follow-up. The research questions of this study were as follows:
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How significant is the BIG score in childhood traumatic brain injury? Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-15 Nazan Ulgen Tekerek, Erdem Cebisli, Mine Erkan, Alper Koker, Oguz Dursun
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Endoscopic callosotomy as a minimally invasive approach to treat paediatric refractory epilepsy: case series Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-14 Islam Abdelsamad, Mohamed Hasan
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Undiagnosed sagittal synostosis as cause of “idiopathic” intracranial hypertension Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-14 Joshua Pepper, Saloni Bhattacharyya, Pasquale Gallo
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Advancing glenohumeral dysplasia treatment in brachial plexus birth injury: the end-to-side spinal accessory to suprascapular nerve transfer technique Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-14 Md Sibat Noor, Nathan Khabyeh-Hasbani, Mandana Behbahani, Steven M. Koehler
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Concurrent spinal meningioma and giant invasive schwannoma without neurofibromatosis in children: A case report and literature review Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-13 Yaxiong Li, Yan Li, Jianfeng Liu, Chao Pang, Conghui Li
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Risk factors associated with intraventricular hemorrhage in very-low-birth-weight premature infants Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-13 Alejandra Guadalupe Puerta-Martínez, Esteban López-Garrido, José Miguel Guerrero-Nava, Rodrigo Vargas-Ruiz, Hadassa Yuef Martínez-Padrón
Purpose To analyze the association between risk factors and severe intraventricular hemorrhage (grade II–IV) in PNB under 1500 g. Methods Multicenter, retrospective, analytical, case–control study in PNB under 34 weeks and under 1500 g admitted to the NICU. Case: PNB with severe intraventricular hemorrhage (grade II–IV). Logistic regression analysis was used to adjust for IVH-associated variables and
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Evaluating the potential role of determinants of health on encephalocele patient outcomes — a combined retrospective study and systematic review Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-12 Victoria A. Pinilla Escobar, W. Austin Wyant, Luca H. Debs, Aria Jamshidi, Erin N. Kiehna, Heather J. McCrea
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Ventriculo-gallbladder shunt: case series and literature review Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-08 Sandrieli Afornali, R. Fedatto Beraldo, A. Keijiro Maeda, C. Alberto Mattozo, R. Nascimento Brito, Anil Ergen, M. Charles Pereira, Bipin Chaurasia
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Secondary metopic craniosynostosis after posterior cranial decompression in cloverleaf skull deformity Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-07
Abstract Cloverleaf skull deformity or Kleeblattschadel syndrome is a severe condition where multiple cranial sutures are absent and prematurely fused, leading to a trilobate head shape. The remaining open sutures or fontanelles compensate for rapid brain expansion, while the constricted fused calvarium restricts brain growth and results in increased intracranial pressure. Recent data show that early
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Intramedullary spinal cord tumors in pediatric patients presenting later with brain lesions: case series and systematic review of the literature Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-07 Bassel Bali, Austin Sellers, Angel Chinea, George I. Jallo, Nir Shimony
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Surgical revascularization as a procedure to prevent neurological complications in children with moyamoya syndrome associated with neurofibromatosis I: a single institution case series Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-06 Alberto Morello, Marcello Scala, Irene Schiavetti, Maria Cristina Diana, Mariasavina Severino, Domenico Tortora, Gianluca Piatelli, Marco Pavanello
Background The optimal timing and surgical approach for surgical revascularization in patients with moyamoya syndrome (MMS) associated with neurofibromatosis type I (NF1) remain so far elusive. We aimed to compare the long-term clinical, radiological, and cognitive effects of different revascularization procedures in a pediatric cohort of NF1-associated MMS. Methods We reviewed the clinical, radiological
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Comparative analysis of linezolid, vancomycin, and hyperbaric oxygen therapies in a rat model of ventriculoperitoneal shunt infection Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-06
Abstract Purpose Staphylococcus epidermidis is the most common causative microorganism of ventriculoperitoneal shunt infections. This study aimed to compare linezolid and vancomycin treatments and to examine the effect of these antibiotics alone and combined with hyperbaric oxygen therapy on the amount of bacterial colonies in the experimental S. epidermidis shunt infection model. Methods A shunt catheter
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Correlation between choroid plexus carcinoma and Li-Fraumeni syndrome: implications of TP53 mutations and management strategies—a case-based narrative review Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-06 Dattatraya Mallik, Swaroop Gopal, Gianluca Scalia, Giuseppe Umana, R T Rajeswarie, Bipin Chaurasia
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Multifocal atypical teratoid/rhabdoid tumour in an infant—a rare case report Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-02 Ashwin Pai, G Lakshmi Prasad, Geetha Vasudevan, Deepak M Nayak
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The epidemiologic associations of food availability with national incidence and mortality rates of pediatric central nervous system tumors Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-02-01 Victor M. Lu, Toba N. Niazi
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Evaluation of neurocognitive and social developments after craniosynostosis surgery Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-01-31
Abstract Objective The study focused on assessing the potential neurocognitive and social developmental issues in children with non-syndromic craniosynostosis (NSC) who received optimal surgical treatment. The primary objective was to determine whether NSC, even after optimal surgical treatment, could have negative effects on brain development. Methods The study included a total of 73 pediatric patients
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Correction: Transcutaneous ultrasound level check for selective dorsal rhizotomy Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-01-30 C. L. Gelder, I. Sataite, R. S. Chave-Cox, J. R. Goodden
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Super-selective Wada test for pre-surgical leg motor function assessment: A case report Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-01-29 Alexander Kuruvilla, Charles J. Sadle, Ian Mutchnick, Samir Karia, Jeetendra Sah, Rebecca Stilp, Shervin Dashti, Cemal Karakas
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Utility of brain imaging in pediatric patients with a suspected accidental spinal injury but no brain injury-related symptoms Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-01-27 Aapo Sirén, Mikko Nyman, Johanna Syvänen, Kimmo Mattila, Jussi Hirvonen
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National multicentered retrospective review of clinical and intraoperative factors associated with the development of cerebellar mutism after pediatric posterior fossa tumor resection Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-01-27
Abstract Background Cerebellar mutism (CM) is characterized by a significant loss of speech in children following posterior fossa (PF) surgery. The biological origin of CM remains unclear and is the subject of ongoing debate. Significant recovery from CM is less likely than previously described despite rigorous multidisciplinary neuro-rehabilitational efforts. Methods A national multi-centered retrospective
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Pediatric sellar teratoma – Case report and review of the literature Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-01-26 Katja Kürner, Ladina Greuter, Michel Roethlisberger, Yves Brand, Stephan Frank, Raphael Guzman, Jehuda Soleman
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Progressive vascular tumor in infant: A case report and literature review of PIK3CA vascular malformation Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-01-24 Allison Medina, Laura Zima, Autumn Atkinson, Neethu M. Menon, Meenakshi Bhattacharjee, Eliana Bonfante, David I. Sandberg, Matthew R. Greives, Manish Shah
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Impact of selective dorsal rhizotomy to cerebral palsy children caregivers’ burden Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-01-22 Bernardo Assumpcao de Monaco, Alessandra Alves Du Rocher Candido, Manoel Jacobsen Teixeira, Eduardo Joaquim Lopes Alho
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Rathke’s cyst with xanthogranulomatous change or chronic cystic craniopharingioma? A rare case Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-01-13 Gabriele Gaggero, Francesca Vitulli, Antonia Ramaglia, Alice Antico, F. Rikki Canevari, Gianluca Piatelli, Diego Criminelli Rossi
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Retroflexed dens in paediatric Chiari 1 patients and implications: Single centre retrospective study Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-01-13 Bobby Sachdev, Vesta S. Najmi, Desiderio Rodrigues, Guirish A. Solanki, Fardad T. Afshari
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Navigating the complexities of encephalocraniocutaneous lipomatosis: a case series and review Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-01-13 Marco Pavanello, Liliana Piro, Arianna Roggero, Andrea Rossi, Matteo Cataldi, Gianluca Piatelli
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Natural history of Chiari I malformation with syrinx and dilatation of the central canal in the pediatric population: the CHEO experience Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-01-12 Maria Fernanda Dien Esquivel, Neetika Gupta, Christian Alfred O’Brien, Vid Bijelić, Nick Barrowman, Nagwa Wilson, Albert Tu
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An unusual presentation of de novo RAC3 variation in prenatal diagnosis Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-01-12 Colombine Meunier, Marie Cassart, Karole Kostyla, Nicolas Simonis, Olivier Monestier, Aude Tessier
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CSF and venous blood flow from childhood to adulthood studied by real-time phase-contrast MRI Childs Nerv. Syst. (IF 1.4) Pub Date : 2024-01-11 Prativa Sahoo, Jost M. Kollmeier, Nora Wenkel, Simon Badura, Jutta Gärtner, Jens Frahm, Steffi Dreha-Kulaczewski