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Prognostic value of left atrial reverse remodelling in heart failure with preserved ejection fraction. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-11-20 Yuxi Sun,Qiang Fu,Gary Tse,Lin Bai,Jiani Liu,Hongyan He,Shuang Zhao,Mimi Tse,Ying Liu
OBJECTIVES Left atrial reverse remodelling (LARR) reflects an improvement in the function or structure. However, it is unclear whether the presence of LARR is associated with better outcomes in patients with heart failure with preserved ejection fraction (HFpEF). METHODS The study was a monocentric retrospective cohort one. Consecutive HFpEF patients admitted to the hospital between 1 January 2018
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Nonpharmacological interventions for 'no-option' refractory angina patients. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-11-09 Yoav Paz,Yair Levy,Liza Grosman-Rimon,Amihay Shinfeld
Refractory angina pectoris (RAP) defined as chronic anginal chest pain because of coronary artery disease (CAD) is a major problem. The increase in the number of patients with RAP in recent years is because of the increasing aging population and improved survival rates among patients with CAD. Management of patients with RAP is often extremely challenging. In this review, we present several interventional
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Edoxaban and/or colchicine in outpatients with COVID-19: rationale and design of the CONVINCE trial. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-11-03 Antonio Landi,Nuccia Morici,Pascal Vranckx,Enrico Frigoli,Luca Bonacchini,Barbara Omazzi,Moreno Tresoldi,Claudio Camponovo,Tiziano Moccetti,Marco Valgimigli
BACKGROUND An excessive inflammatory response and a hypercoagulable state are not infrequent in patients with coronavirus disease-2019 (COVID-19) and are associated with adverse clinical outcomes. However, the optimal treatment strategy for COVID-19 patients managed in the out-of-hospital setting is still uncertain. DESIGN The CONVINCE (NCT04516941) is an investigator-initiated, open-label, blinded-endpoint
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Prognostic value of coronary microvascular dysfunction in patients with aortic stenosis and nonobstructed coronary arteries. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-11-03 Ayman A Mohammed,Hengbin Zhang,Siqi Li,Lu Liu,Redhwan M Mareai,Yawei Xu,Fuad A Abdu,Wenliang Che
BACKGROUND Patients with aortic valve stenosis have been postulated to have coronary microvascular dysfunction (CMD) contributing to the clinical symptoms and adverse outcomes. The coronary angiography (CAG)-derived index of microcirculatory resistance (caIMR) is proposed as a novel, less invasive and pressure-wire-free index to assess CMD. This study aimed to quantify CMD assessed by caIMR and investigate
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Impact of proteinuria on long-term prognosis in patients with coronary artery disease. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-11-03 Hiroshi Funakubo,Akihito Tanaka,Akihiro Tobe,Takeshige Kunieda,Yoshiaki Kubota,Naoki Yoshioka,Satoshi Otsuka,Nobutaka Kudo,Yoshinori Shirai,Kenji Furusawa,Hideki Ishii,Toyoaki Murohara
BACKGROUND This study aimed to investigate the association between proteinuria and long-term prognosis in patients with coronary artery disease. METHODS This was a single-center observational study. A total of 1351 patients were identified who underwent percutaneous coronary intervention, and whose urine data were available. Patients were divided into two groups according to the presence (n = 245)
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SCN5A mutation is associated with a higher Shanghai Score in patients with type 1 Brugada ECG pattern. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-10-30 Laura Tonelli,Cristina Balla,Marianna Farnè,Alice Margutti,Eugenia Tiziana Maniscalchi,Gaetano De Feo,Assunta Di Domenico,Martina De Raffele,Antonio Percesepe,Vera Uliana,Valeria Barili,Walter Serra,Biagio Sassone,Santo Virzì,Elia De Maria,Giulia Parmeggiani,Gabriele Egidy Assenza,Elena Biagini,Vanda Parisi,Mauro Biffi,Valeria Carinci,Enrica Perugini,Paola Imbrici,Alessandra Ferlini,Matteo Bertini
AIMS Brugada syndrome (BrS) is an inherited arrhythmic disease characterized by a coved ST-segment elevation in the right precordial electrocardiogram leads (type 1 ECG pattern) and is associated with a risk of malignant ventricular arrhythmias and sudden cardiac death. In order to assess the predictive value of the Shanghai Score System for the presence of a SCN5A mutation in clinical practice, we
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Timing, positioning and ancillary therapies: the triad for successful Impella RP. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-10-30 Stephanie Bertolin,Giulia Maj,Gioel Gabrio Secco,Alberto Pullara,Riccardo Gherli,Astrid Cardinale,Nicoletta D'Ettore,Corrado Cavozza,Andrea Audo,Federico Pappalardo
Clear clinical guidelines for the assessment and treatment of right ventricular failure (RVF) remain an unmet need. Although high complexity patients are common in this setting, the ideal management remains uncertain, resulting in high mortality rates despite presumably optimal medical therapy. Timely treatment with Impella RP may offer benefits by supplying circulatory support during the acute RVF
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Intravascular ultrasound-guided 'OrbiTripsy' for a severely calcified neo-atherosclerotic coronary in-stent restenosis. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-10-17 Attilio Restivo,Emiliano Bianchini,Michele Bellamoli,Andrea Buono,Luca Bettari,Alessio Stanzione,Benjamin De Ornelas,Diego Maffeo
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Implantable-cardioverter-defibrillator after ST-elevation myocardial infarction: when and how frequently is it implanted and what is the rate of appropriate interventions? Insight from Trieste registry. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-10-16 Andrea Pezzato,Enrico Fabris,Caterina Gregorio,Marco Cittar,Stefano Contessi,Cosimo Carriere,Gerardina Lardieri,Massimo Zecchin,Andrea Perkan,Gianfranco Sinagra
BACKGROUND There are limited data on implantable-cardioverter-defibrillator (ICD) implantation after ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI). Therefore, we evaluated when and how frequently an ICD is implanted after pPCI, the rate of appropriate ICD interventions, and predictors of ICD implantation. METHODS We analyzed STEMI patients
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Prognostic impact of red blood cell distribution width in chronic heart failure patients with left ventricular dysfunction. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-10-01 Ana Isabel Ferreira,João Enes Silva,Nuno Melo,Diana Oliveira,Clara Silva,Maria Lume,Joana Pereira,Jorge Almeida,José Paulo Araújo,Patrícia Lourenço
AIMS Red blood cell (RBC) distribution width (RDW) measures RBC variations in size. Higher RDW values have been associated with poor outcome in acute heart failure (HF). We aimed to assess the prognostic impact of the RDW in chronic HF. METHODS We retrospectively analysed a cohort of chronic HF patients with left ventricular systolic dysfunction followed in our HF clinic between January 2012 and May
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Serum levels of 25-OH vitamin D levels predict cognitive impairments among acute coronary syndrome patients. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-10-01 Mengzhu Fu,Xing Li,Zhenzhen Hu,Caixia Yin,Wenzhuo Dai,Huihui Song
BACKGROUND The cognitive impairment after percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS) has become a crucial clinical concern that cannot be ignored. However, studies on the early warning factors of cognitive impairment after PCI are still insufficient. METHODS This study reviewed the postoperative cognitive function of 284 patients who underwent PCI in our
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Out-of-hospital cardiac arrest and the role of early PCI: will patients with non-ST-segment elevation MI get any benefit from an early invasive approach? J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-10-01 Maddalena Lettino,Pietro Vandoni
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Del Nido cardioplegia for cardiac surgery requiring cardiopulmonary bypass: is the best yet to come? J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-10-01 Wael Saade,Giacomo Frati,Giuseppe Biondi-Zoccai,Carlo Gaudio
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Colchicine added to standard therapy further reduces fibrosis in pigs with myocardial infarction. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-09-29 Alberto Aimo,Daina Martinez-Falguera,Andrea Barison,Veronica Musetti,Silvia Masotti,Paolo Morfino,Claudio Passino,Giulia Martinelli,Angela Pucci,Veronica Crisostomo,Francisco Sanchez-Margallo,Virginia Blanco-Blazquez,Carolina Galvez-Monton,Michele Emdin,Antoni Bayes-Genis
BACKGROUND The anti-inflammatory drug colchicine improves the outcome of patients with myocardial infarction (MI). As an intense inflammatory and fibrotic response after MI may lead to scar expansion and left ventricular (LV) remodeling, the clinical benefit of colchicine could be related to a positive effect on the infarct scar and LV remodeling. METHODS Pigs underwent left anterior descending artery
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Major cardiovascular events increase in long-term proprotein convertase subtilisin/kexin type 9 inhibitors therapy: the Tuscany cost-effective study. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-09-29 Francesco Sbrana,Beatrice Dal Pino,Federico Bigazzi,Andrea Ripoli,Carmen Corciulo,Giuseppa Lo Surdo,Stefania Biagini,Tiziana Sampietro,
BACKGROUND Proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) represent a breakthrough in the treatment of hypercholesterolemia. The aim of this study was to perform a multicentre prospective analysis on the effects of PCSK9i since their distribution in Italy. METHODS During the study period (July 2017 to February 2022) 246 patients (mean age 61 ± 11 years, male 73%) who were evolocumab
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Sodium-dependent glucose transporter 2 inhibition and the atrial antiremodelling effects in HFrEF patients. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-09-29 Paolo N Marino
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The implementation of telemedicine in the follow-up after catheter ablation of arrhythmias: do we still need in-office consultations? J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-09-29 Giacomo Mugnai,Valeria Ferrero,Luca Tomasi,Bruna Bolzan,Francesca Vassanelli,Flavio Luciano Ribichini
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Cardiovascular risk stratification in young women: the pivotal role of pregnancy. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-09-29 Anna Vittoria Mattioli,Francesca Coppi,Valentina Bucciarelli,Sabina Gallina
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The epidemiology and mortality of patients with atrial fibrillation: a complex landscape. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-09-29 Giuseppe Boriani,Niccolò Bonini,Jacopo Francesco Imberti
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Smoking and cardiovascular disease in patients with type 2 diabetes: a prospective observational study. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-09-27 Peder Af Geijerstam,Fredrik Janryd,Fredrik H Nyström
BACKGROUND Cigarette smoking is a major risk factor for cardiovascular disease. In type 2 diabetes mellitus (T2D), medications such as antihypertensives and statins can reduce the increased cardiovascular risk. The aim of this study was to evaluate the impact of cigarette smoking on major adverse cardiovascular event (MACE) and all-cause mortality in patients with T2D in a relatively well treated Swedish
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Coronary computed tomography angiography and optical coherence tomography imaging of an intraplaque hemorrhage. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-09-25 Michele Russo,Micol Coccato,Gerlando Preti,Martino Cinquetti,Franco Macor,Nadir Sitta,Francesca Carchesio,Simone Cattarin,Gianluca Piccoli,Roberto Mantovan
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A novel ECG algorithm to differentiate between ventricular arrhythmia from right versus left ventricular outflow tract. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-09-15 Wei Zhang,Kui Huang,Jun Qu,Guoying Su,Xinyun Li,Qingzan Kong,Hua Jiang
AIM The aim of this study was to evaluate the accuracy of the diagnostic criteria for determining the origin of outflow tract ventricular arrhythmia (OTVA) and develop an ECG algorithm to predict its origin. METHOD We analyzed the ECGs of 100 patients with OTVA who underwent successful ablation. The QRS complex was measured during sinus rhythm and ventricular arrhythmia. After the ECG algorithm was
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An incidental finding of a challenging mitral mass: cardiac surgery or not? J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-09-05 Edoardo Sciatti,Anna Merlo,Aurelia Grosu,Giulio Balestrieri,Umbertina Veritti,Vincenzo Duino,Michele Senni
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Risk of incident pericarditis after coronavirus disease 2019 recovery: a systematic review and meta-analysis. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-09-05 Marco Zuin,Massimo Imazio,Gianluca Rigatelli,Giampaolo Pasquetto,Claudio Bilato
AIMS Data regarding the risk of incident pericarditis in coronavirus disease 2019 (COVID-19) recovered patients are lacking. We determined the risk of incident pericarditis after COVID-19 infection by performing a systematic review and meta-analysis of available data. METHODS Following the PRISMA guidelines, we searched MEDLINE and Scopus to locate all articles published up to 11 February 2023 reporting
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Preoperative angiography-derived fractional flow reserve may predict coronary artery bypass grafting occlusion and disease progression. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-09-01 Saima Mushtaq,Carlo Gigante,Edoardo Conte,Teresa Maria Capovilla,Jeroen Sonck,Alessandra Tanzilli,Emanuele Barbato,Giovanni Monizzi,Marta Belmonte,Bernard De Bruyne,Antonio L Bartorelli,Matteo Schillaci,Davide Marchetti,Maria Ludovica Carerj,Gianluca Pontone,Carlos Collet,Daniele Andreini
BACKGROUND Graft occlusion after coronary artery bypass grafting (CABG) has been associated with competitive flow of native coronary arteries. OBJECTIVES To assess with coronary computed tomography angiography (CCTA) graft occlusion and coronary artery disease (CAD) progression of native vessels after CABG and their relationship with angiography-derived vessel fractional flow reserve (vFFR) performed
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Atrial fibrillation in vascular surgery: a systematic review and meta-analysis on prevalence, incidence and outcome implications. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-09-01 Vincenzo L Malavasi,Federico Muto,Pietro A C M Ceresoli,Matteo Menozzi,Ilaria Righelli,Luigi Gerra,Marco Vitolo,Jacopo F Imberti,Davide A Mei,Niccolò Bonini,Mauro Gargiulo,Giuseppe Boriani
AIMS To know the prevalence of atrial fibrillation (AF), as well as the incidence of postoperative AF (POAF) in vascular surgery for arterial diseases and its outcome implications. METHODS We performed a systematic review and meta-analysis following the PRISMA statement. RESULTS After the selection process, we analyzed 44 records (30 for the prevalence of AF history and 14 for the incidence of POAF)
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Urgent coronary angiography in out-of-hospital cardiac arrest: a retrospective single centre investigation. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-09-01 Falvia Caniato,Chiara Lazzeri,Manuela Bonizzoli,Alessio Mattesini,Stefano Batacchi,Francesco Cappelli,Carlo Di Mario,Adriano Peris
AIMS The role of immediate coronary angiography (CAG) with percutaneous coronary intervention (PCI) in patients who present with ST-segment elevation myocardial infarction (STEMI) and cardiac arrest is well recognized. However, the role of immediate angiography in patients after cardiac arrest without STEMI is less clear. We assessed whether urgent (<6 h) CAG and PCI (whenever needed) was associated
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Overcoming limitations in out-of-hospital cardiac arrest extracorporeal cardiopulmonary resuscitation: optimizing assessment and patient selection for future clinical trials. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-09-01 Edouard Lansiaux,Valentin Playe,Nityanand Jain
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Treatment of aortic stenosis in dialysis: a necessary update in a challenging population. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-09-01 Luca Branca,Marco Metra,Marianna Adamo
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Impact of age on pre-procedural TIMI flow in STEMI patients undergoing primary percutaneous coronary intervention. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-09-01 Monica Verdoia,Rocco Gioscia,Orazio Viola,Marta Francesca Brancati,Pier Luigi Soldà,Andrea Rognoni,Giuseppe De Luca,
BACKGROUND Advanced age is a major determinant of impaired prognosis among patients with ST-segment elevation myocardial infarction (STEMI). However, the mechanisms associated with suboptimal reperfusion and enhanced complications are still largely undefined. The aim of the present study was to assess the impact of age on the angiographic findings and the procedural results of primary percutaneous
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Practical patient care appraisals with use of new potassium binders in heart failure and chronic kidney diseases. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-08-30 Michele Senni,Edoardo Sciatti,Elisabetta Bussalino,Emilia D'Elia,Maura Ravera,Ernesto Paoletti
Hyperkalaemia is a life-threatening condition leading to significant morbidity and mortality. It is common in heart failure and in chronic kidney disease (CKD) patients due to the diseases themselves, which often coexist, the high co-presence of diabetes, the fluctuations in renal function, and the use of some drugs [i.e. renin-angiotensin-aldosterone system (RAAS) inhibitors]. Hyperkalaemia limits
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The relationship between spontaneous coronary artery dissection and COVID-19. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-08-29 Keitaro Akita,Aaqib Malik,Alexandros Briasoulis,Toshiki Kuno
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Effect of sodium-glucose cotransporter 2 inhibitors on left atrial remodeling and prognosis in patients with type 2 diabetes and heart failure with reduced ejection fraction. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-08-24 Songqi Yu,Yuxi Sun,Ning Wang,Xin Lv,Jinping Si,Xinxin Zhang,Yanli Zhang,Ying Liu
AIMS Sodium-glucose cotransporter 2 inhibitors (SGLT2is) have been found to minimize hospitalization for heart failure and cardiovascular death. Cardiac reverse remodeling may be a mechanism responsible for the favorable clinical efficacy of SGLT2is on heart failure. To date, few studies have examined their effects on the left atrium. Therefore, the purpose of this study was to explore whether SGLT2is
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Positive association between alkaline phosphatase and arteriosclerosis: a cross-sectional study. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-08-13 Yaqing Zhou,Chen Chen,Long Bai,Limei Jia,Baojin Lu,Guoqiang Gu,Wei Cui
AIMS Serum alkaline phosphatase (ALP) is known to be associated with cardiovascular events and cerebral arteriosclerosis. However, the link between ALP and early arteriosclerosis remains unclear. This study investigated the relationship between ALP and early arteriosclerosis assessed by brachial-ankle pulse wave velocity (Ba-PWV). METHODS This retrospective analysis included 5011 participants who underwent
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Echocardiographic screening in pediatric asymptomatic or paucisymptomatic coronavirus disease 2019 outpatients: is it a useful test or an excess of zeal? J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-08-09 Paolo Alberto Gasparini,Elisa Lodi,Eleonora Rodighiero,Jonathan Rosero Morales,Giuseppe Fantini,Maria Grazia Modena
INTRODUCTION Data regarding echocardiographic findings during follow-up of asymptomatic or pauci-symptomatic coronavirus disease 2019 (COVID-19) are scarce in pediatric patients. The aim of the present study is to assess post-COVID-19 sequelae through echocardiography in children who have experienced mild SARS-CoV-2. METHODS This single-center, retrospective, observational study enrolled a cohort of
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Estimating the impact of single pill combination therapy for hypertension: projections of patient outcomes in Italy. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-08-07 Claudio Borghi,Denis Granados
INTRODUCTION Hypertension affects almost a third of the Italian population and is a major risk factor for cardiovascular disease. Management of hypertension is often hindered by poor adherence to complex treatment regimens. This analysis aimed to estimate the 10-year clinical outcomes associated with single pill combination (SPC) therapies compared with other treatment pathways for the management of
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Trends in occurrence of takotsubo syndrome and association with SARS-CoV-2 infection and COVID-19 vaccination. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-08-07 Bar Rosh,Ibrahim Naoum,Nili Stein,Ronen Jaffe,Walid Saliba
AIMS Takotsubo syndrome (TTS) is a serious heart disease associated with significant morbidity and mortality. TTS has been related to SARS-CoV-2 infection and COVID-19 vaccine; however, the current data are scarce. We aimed to examine the associations between SARS-CoV-2 infection and its vaccine with TTS. METHODS We conducted a nested case-control study in a cohort of 3 237 909 adults from the largest
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Serum albumin and prognosis in elderly patients with nonischemic dilated cardiomyopathy. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-08-04 Xinyi Li,Xiaonan Zhang,Zhigang Zeng,Wenzhi Mai,Zishan Peng,Binjia Li,Wanzi Hong,Yaoxin Liu,Fen Shu,Jiehua Tang,Lishu Xu,Ning Tan,Jinjin Ma,Lei Jiang
AIMS Hypoalbuminemia was extensively used to diagnose malnutrition in older adults. Malnutrition was associated with mortality in elderly patients with cardiovascular diseases. The relationship between hypoalbuminemia and clinical outcomes in elderly patients with nonischemic dilated cardiomyopathy (NIDCM) remains unknown. METHODS A total of 1058 consecutive patients with NIDCM (age ≥60 years) were
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Mitral valve surgery in acute infective endocarditis: long-term outcomes of mitral valve repair versus replacement. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-08-03 Lorenzo Di Bacco,Michele D'Alonzo,Massimiliano Di Mauro,Rocco Davide Petruccelli,Massimo Baudo,Camila Mayorga Palacios,Stefano Benussi,Claudio Muneretto,Fabrizio Rosati
AIMS Timing and surgical strategies in acute infective endocarditis are still questionable. We sought to investigate clinical outcomes of patients undergoing mitral valve repair (MVR) compared with mitral valve replacement [mitral valve prosthesis (MVP)] for acute infective endocarditis. METHODS From 2004 to 2019, 109 consecutive patients with acute mitral valve infective endocarditis were retrospectively
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The multidisciplinary Heart Team approach for patients with cardiovascular disease: a step towards personalized medicine. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-08-02 Andrea Mazza,Mauro Iafrancesco,Piergiorgio Bruno,Giovanni Alfonso Chiariello,Carlo Trani,Francesco Burzotta,Federico Cammertoni,Annalisa Pasquini,Giovanni Diana,Raphael Rosenhek,Giovanna Liuzzo,Alessia Rabini,Andrea Flex,Abdallah Raweh,Filippo Crea,Massimo Massetti
AIMS Despite general agreement on the benefits of the Heart Team approach for patients with cardiac diseases, few data are available on its real impact on the decision-making process. The aim of the study is to define the evolution over time of the level of agreement with the systematic discussion of patients in the Heart Team and to evaluate the adherence to the Heart Team recommendations and the
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First-in-man parallel implantation of a coronary sinus Reducer and biventricular pacemaker. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-08-02 Dimitris Tsiachris,Francesco Giannini,Christos-Konstantinos Antoniou,Kyriakos Dimitriadis,Christodoulos Stefanadis,Konstantinos Tsioufis
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Cost-effectiveness of empagliflozin in heart failure patients irrespective of ejection fraction in England. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-07-25 Spyros Kolovos,Leana Bellanca,Harinala Groyer,Giuseppe Rosano,Jennifer Gaultney,Stephan Linden
AIMS Heart failure (HF) is a complex syndrome commonly categorized into two main phenotypes [left ventricular ejection fraction (LVEF) below or above 40%], and although empagliflozin is the first approved medication with proven clinical effectiveness for both phenotypes, its cost-effectiveness of treating the entire HF population remains unknown. METHODS The analysis was performed utilizing two preexisting
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The safety of sodium-glucose co-transporter 2 inhibitors in patients with left ventricular assist device - a single center experience. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-07-14 Gassan Moady,Binyamin Ben Avraham,Shaul Aviv,Osnat Itzhaki Ben Zadok,Shaul Atar,Mahmood Abu Akel,Tuvia Ben Gal
AIMS Sodium-glucose co-transporter 2 (SGLT2) inhibitors are used increasingly for patients with heart failure or chronic kidney disease to improve cardiac and renal outcomes. The use of these medications in patients with left ventricular assist devices (LVAD) is still limited and lacks evidence regarding the safety profile. In this study, we aimed to report our experience in treating 20 patients, supported
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Prognostic role of tricuspid annular plane systolic excursion/pulmonary artery systolic pressure ratio in patients hospitalized for acute heart failure. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-08-01 Andrea Bonelli,Matteo Pagnesi,Riccardo Maria Inciardi,Assunta Castiello,Edoardo Sciatti,Valentina Carubelli,Carlo Mario Lombardi,Marco Metra,Enrico Vizzardi
BACKGROUND The role of TAPSE/PASP, a measurement of right ventricular to pulmonary artery coupling, in patients hospitalized for acute heart failure (AHF) is poorly described. OBJECTIVES To evaluate the prognostic impact of TAPSE/PASP in AHF. METHODS This retrospective single-center study included patients hospitalized for AHF between January 2004 and May 2017. TAPSE/PASP was evaluated as a continuous
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Ventriculo-arterial uncoupling in acute heart failure: right heart is the matter. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-08-01 Giulio Savonitto,Gianfranco Sinagra,Davide Stolfo
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Left-to-right ventricular volume ratio and outcome in heart failure with preserved ejection fraction. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-08-01 Alberto Aimo,Albert Teis,Gizem Kasa,Gladys Juncà,Josep Lupón,Mar Domingo,Elena Ferrer,Nuria Vallejo,Germán Cediel,Pau Codina,Jorge López-Ayerbe,Georgios Georgiopoulos,Nicola Martini,Michele Emdin,Antoni Bayes-Genís,Claudio Rapezzi,Victoria Delgado
BACKGROUND Age-specific and gender-specific reference values for left ventricular (LV) and right ventricle volumes are available. The prognostic implications of the ratio between these volumes in heart failure and preserved ejection fraction (HFpEF) have never been evaluated. METHODS We examined all HFpEF outpatients undergoing a cardiac magnetic resonance from 2011 to 2021. The left-to-right ventricular
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Left-to-right ventricular volume ratio predicts prognosis in heart failure with preserved ejection fraction: when simple is better. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-08-01 Gloria Santangelo,Andrea Faggiano,Giuseppe Locatelli,Stefano Carugo
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Cardiovascular imaging updates and future perspectives. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-08-01 Giada Colombo,Matteo Cameli,Marco Metra,Riccardo M Inciardi
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Efficacy of SGLT2-inhibitors across different definitions of heart failure with preserved ejection fraction. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-08-01 Vincenzo De Marzo,Gianluigi Savarese,Italo Porto,Marco Metra,Pietro Ameri
AIMS Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have been evaluated in phase 3 randomized-controlled trials (RCTs) that enrolled individuals with heart failure and preserved ejection fraction (HFpEF) based on detailed clinical, biochemical, and echocardiographic criteria (hereafter HF-RCTs), and in cardiovascular outcomes trials (CVOTs) in diabetic patients, in which the diagnosis of HFpEF
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Effect of coronavirus disease 2019 pandemic on heart failure hospitalization rates and disparities: a National Inpatient Sample study. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-07-06 Ayodeji I Ilelaboye,Ufuk Vardar,Naveen Baskaran,Abdultawab Shaka,Sean DeAngelo,Hafeez Shaka
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Trends in age- and sex-specific atrial fibrillation/flutter mortality in Italy between 2003 and 2017. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-07-05 Marco Zuin,Michele Malagù,Francesco Vitali,Martina De Raffele,Cristina Balla,Matteo Bertini
AIMS We sought to assess the atrial fibrillation/flutter (AF/AFL) mortality rates and relative trends among the Italian population between 2003 and 2017. METHODS Data regarding the cause-specific mortality and population size by sex in 5-year age groups were extracted from the World Health Organization (WHO) global mortality database. Decedents reporting the codes I48 were extracted accordingly to
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Longitudinal analysis of pump parameters over long-term support with the HeartMate 3 left ventricular assist device. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-06-30 Filippo Consolo,Marina Pieri,Vittorio Pazzanese,Anna Mara Scandroglio,Federico Pappalardo
AIMS Recurrence of heart failure emerged as the main cause of long-term mortality in patients implanted with the HeartMate 3 (HM3) left ventricular assist device (LVAD). We aimed at deriving a possible mechanistic rationale of clinical outcomes and analyzed longitudinal changes in pump parameters over prolonged HM3 support to investigate long-term effects of pump settings on left ventricular mechanics
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Effect of acute CORticosteroids on conduction defects after Transcatheter Aortic Valve Implantation: the CORTAVI study. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-06-28 Lucy Barone,Saverio Muscoli,Martina Belli,Marco Di Luozzo,Domenico Sergi,Massimo Marchei,Francesca R Prandi,Giuseppe Uccello,Francesco Romeo,Francesco Barillà
AIMS Conduction abnormalities, requiring a permanent pacemaker (PPM), are the most common electrical complications after transcatheter aortic valve implantation (TAVI). The exact mechanism for conduction system defects is not yet clear. The local inflammatory process and edema are thought to play a role in the development of electrical disorders. Corticosteroids are effective anti-inflammatory and
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Natural history and clinical burden of moderate aortic stenosis: a systematic review and explorative meta-analysis. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-06-26 Martina Morelli,Michele Galasso,Giuseppe Esposito,Francesco Stefano Soriano,Stefano Nava,Caterina Da Pozzo,Irene Bossi,Emanuela Piccaluga,Giuseppe Bruschi,Alessandro Maloberti,Fabrizio Oliva,Jacopo Andrea Oreglia,Cristina Giannattasio,Claudio Montalto
AIMS The mortality risk of patients with moderate aortic stenosis is not well known, but recent studies suggested that it might negatively affect prognosis. We aimed to assess the natural history and clinical burden of moderate aortic stenosis and to investigate the interaction of patients' baseline characteristics with prognosis. METHODS Systematic research was conducted on PubMed. The inclusion criteria
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Telemedicine for the treatment of heart failure: new opportunities after COVID-19. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-06-26 Maria Giulia Bellicini,Francesca Pia D'Altilia,Cristina Gussago,Marianna Adamo,Carlo Mario Lombardi,Daniela Tomasoni,Riccardo Maria Inciardi,Marco Metra,Matteo Pagnesi
During the Coronavirus Disease 2019 (COVID-19) pandemic, the epidemiology of heart failure significantly changed with reduced access to health system resources and a worsening of patients' outcome. Understanding the causes of these phenomena could be important to refine the management of heart failure during and after the pandemic. Telemedicine was associated with an improvement in heart failure outcomes
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Stroke risk in radial versus femoral approach in coronary intervention: an updated systematic review and meta-analysis. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-06-26 Aditya M Desai,Darshi Desai,Arnold Gan,Devanshi Mehta,Kimberly Ding,Frances Gan,Tanawan Riangwiwat,Prabhdeep S Sethi,Ashis Mukherjee,Ramdas G Pai,Narut Prasitlumkum
AIM Peri-cardiac catheterization (CC) stroke is associated with increased morbidity and mortality. Little is known about any potential difference in stroke risk between transradial (TR) and transfemoral (TF) approaches. We explored this question through a systematic review and meta-analysis. METHODS MEDLINE, EMBASE, and PubMed were searched from 1980 to June 2022. Randomized trials and observational
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del Nido versus blood cardioplegia in adult cardiac surgery: a meta-analysis. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-06-26 Pietro Giorgio Malvindi,David H Tian,Olimpia Bifulco,Paolo Berretta,Jacopo Alfonsi,Mariano Cefarelli,Tristan D Yan,Marco Di Eusanio
AIMS Initially developed for myocardial protection in immature cardiomyocytes, del Nido cardioplegia has been increasingly used over the past decade in adult patients. Our aim is to analyse the results from randomized controlled trials and observational studies comparing early mortality and postoperative troponin release in patients who underwent cardiac surgery using del Nido solution and blood cardioplegia
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Albumin use and mortality among intensive care patients with acute heart failure: a retrospective study. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-06-26 Zhenze Yu,Binghua Zhu,Jianxin Ma,Yutin Guan,Yiling Zhou,Hezhi Li,Jinping Zhang
OBJECTIVE Hypoproteinemia is common in patients with acute heart failure, especially in the intensive care unit (ICU). We assessed short-term mortality in patients with acute heart failure for albumin and nonalbumin users. METHODS Our study was a retrospective, observational and single-center study. We included patients with acute heart failure from the Medical Information Mart for Intensive Care-IV
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Cardiovascular prevention in childhood: a consensus document of the Italian Society of Cardiology Working Group on Congenital Heart Disease and Cardiovascular Prevention in Paediatric Age. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-06-26 Francesco Martino,Pier Paolo Bassareo,Eliana Martino,Francesco Romeo,Giuseppe Calcaterra,Pasquale Perrone Filardi,Ciro Indolfi,Savina Nodari,Vincenzo Montemurro,Paolo Guccione,Giovanni Di Salvo,Massimo Chessa,Roberto Pedrinelli,Giuseppe Mercuro,Francesco Barillà,
Cardiovascular diseases (CVD) may be manifested from a very early age. Genetic and environmental (epigenetic) factors interact to affect development and give rise to an abnormal phenotypical expression of genetic information, although not eliciting changes in the nucleotide sequence of DNA. It has been scientifically proven that increased oxidative stress (OS) caused by disease (overweight, obesity
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Porcine bioprostheses for surgical aortic valve replacement: very long-term performance of a third-generation device. J. Cardiovasc. Med. (IF 3.0) Pub Date : 2023-06-26 Amedeo Anselmi,Jacques Tomasi,Marie Aymami,Julien Mancini,Nicolas Nesseler,Thierry Langanay,Erwan Flecher,Jean-Philippe Verhoye
AIMS We aimed at investigating the long-term durability of the Epic bioprosthesis for surgical aortic valve replacement (SAVR) in a single-centre series of 888 implantations (2001-2018), expanding previous evaluations with shorter follow-up. METHODS We retrieved prospectively collected in-hospital data and performed a systematic follow-up focusing on valve-related events (SVD, structural valve deterioration;