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The association between inflammation, arterial stiffness, oxidized LDL and cardiovascular disease in Finnish men with metabolic syndrome – a 15-year follow-up study BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-15 Harri Juhani Saarinen, Jorma Lahtela, Päivi Mähönen, Ari Palomäki
All-cause mortality and cardiovascular disease are increased in subjects with metabolic syndrome (MetS). Risk scores are used to predict individual risk of heart disease. We performed a long-term follow-up study to investigate whether risk scores and cardiovascular risk factors such as arterial stiffness, high-sensitive C-reactive protein (hs-CRP) and oxidized LDL (OxLDL) can be used to predict cardiovascular
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Causal association between helicobacter pylori and atherosclerosis: a two-sample Mendelian randomization BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-15 Xueyi Zhang, Yue Shi, Tielin Li, Ke Chang, Yongyan Gan, Yue Feng, Xianhua Zhou
Helicobacter pylori (H. pylori), according to a number of recent observational studies, is connected to atherosclerosis (AS). However, the link between H. pylori and AS is debatable. In order to calculate the causal relationship between H. pylori and AS, we employed a two-sample Mendelian randomization (MR) analysis. The data for H. pylori were obtained from the IEU GWAS database ( https://gwas.mrcieu
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Apolipoprotein E E3/E4 genotype is associated with an increased risk of type 2 diabetes mellitus complicated with coronary artery disease BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-15 Wenhao Chen, Bin Li, Hao Wang, Guoliang Wei, Kehui Chen, Weihong Wang, Shen Wang, Yuanliang Liu
Dyslipidemia is a co-existing problem in patients with diabetes mellitus (DM) and coronary artery disease (CAD), and apolipoprotein E (APOE) plays an important role in lipid metabolism. However, the relationship between the APOE gene polymorphisms and the risk of developing CAD in type 2 DM (T2DM) patients remains controversial. The aim of this study was to assess this relationship and provide a reference
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Preoperative serum selenium predicts acute kidney injury after adult cardiac surgery BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-14 Guowei Fu, Shuying Bai
The relationship between serum selenium (Se) and acute kidney injury after adult cardiac surgery (CSA-AKI) remains controversial. This study aimed to investigate the association of preoperative Se level with incident CSA-AKI. A retrospective cohort study was conducted on patients who underwent cardiac surgery. The primary outcome was incident CSA-AKI. Multivariable logistic regression models and natural
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Comparing coronary artery cross-sectional area among asymptomatic South Asian, White, and Black participants: the MASALA and CARDIA studies BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-14 R. T. Short, F. Lin, S. Nair, J. G. Terry, J. J. Carr, N. R. Kandula, D. Lloyd-Jones, A. M. Kanaya
South Asian individuals have high risk of atherosclerotic cardiovascular disease (ASCVD). Some investigators suggest smaller coronary artery size may be partially responsible. We compared the left anterior descending (LAD) artery cross-sectional area (CSA) (lumen and arterial wall) among South Asians in the Mediators of Atherosclerosis in South Asians Living in America (MASALA) study with White and
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Voluntary first responders’ experiences of being dispatched to suspected out-of-hospital cardiac arrest in rural areas: an interview study BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-14 Camilla Allert, Bengt Nilsson, Anders Svensson, Ewa K. Andersson
Out-of-hospital cardiac arrest (OHCA) is a leading cause of death, and survival outcomes vary across countries and regions. To improve survival, the European Resuscitation Council Guidelines encourage the implementation of technologies like smartphone applications to alert voluntary first responders (VFRs) who are near a suspected OHCA. VFRs are of great importance in the ´chain of survival´, but there
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Retraction Note: Assessment of fetal intraventricular diastolic fluid dynamics using ultrasound vector flow mapping BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-14 Qinglan Shu, Yi Wang, Xinyi Lin, Shenghua Xie, Zhengyang Wang, Sijia Wang, Lixue Yin
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12872-023-03524-0.
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Predictive value of the serum uric acid to high-density lipoprotein cholesterol ratio for culprit plaques in patients with acute coronary syndrome BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-13 Fuxue Deng, Fang Jia, Yang Sun, Lisha Zhang, Jie Han, Danni Li, Qiang Yang, Rongrong Hou, Wei Jiang
Hyperuricemia and low level of high-density lipoprotein cholesterol (HDL-C) are both risk factors for coronary artery disease (CAD). The uric acid to HDL-C ratio (UHR) has recently been identified as a new inflammatory and metabolic biomarker. However, the relationship between the UHR and coronary culprit plaques has not been fully investigated in patients with acute coronary syndrome (ACS). A total
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Purulent pericarditis caused by methicillin-sensitive Staphylococcus aureus bacteriuria BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-13 Lorraine Mascarenhas, Dzhalal Agakishiev, Morgan Freeman, Scott Hubers
Purulent pericarditis (PP)— a purulent infection involving the pericardial space—requires a high index of suspicion for diagnosis as it often lacks characteristic signs of pericarditis and carries a mortality rate as high as 40% even with treatment. Common risk factors include immunosuppression, diabetes mellitus, thoracic surgery, malignancy, and uremia. Most reported cases of PP occur in individuals
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Effects of staged rehabilitation training on inflammatory factor levels and red blood cell distribution width followingcardiac valve replacement BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-13 Beibei Xing, Pujuan Liu
The current study was conducted aimed atexploring the effects of staged rehabilitation training on the levels of inflammatory factors and red blood cell distribution in patients who underwent cardiac valve replacement. A total of 140 patients who underwent cardiac valve replacement at The First Hospital of Hebei Medical University between April 2021 and November 2022 were included in this study. During
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In emergency hypertension, could biomarkers change the guidelines? BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-13 Mohammad El Tahlawi, Scopus Mohamed Ismail, Ahmed Eldamanhory, Ayman Khorshed, Salem M. Salem
Hypertension may cause target organ damage (TOD). Target blood pressure (BP) management may not be appropriate in some conditions. We aim to assess the impact of targeted BP management in severe hypertension on renal TOD. This is a prospective cohort study involving patients admitted due to severe hypertension (BP > 180/120) associated with any symptoms. The study involved patients referred to the
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GDF-15: a novel biomarker of heart failure predicts short-term and long-term heart-failure rehospitalization and short-term mortality in patients with acute heart failure syndrome BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-12 Paisit Kosum, Noppachai Siranart, Natthinee Mattanapojanat, Somkiat Phutinart, Narisorn Kongruttanachok, Supanee Sinphurmsukskul, Sarawut Siwamogsatham, Sarinya Puwanant, Aekarach Ariyachaipanich
Acute heart failure (AHF) is a potentially life-threatening clinical syndrome, usually requiring hospital admission. Growth Differentiation Factor-15 (GDF-15) is a distant member of the transforming growth factor-β. The increased expression of GDF-15 has been observed during heart failure (HF) and is associated with worse outcomes. However, the relationship between GDF-15 and AHF is not well understood
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Adiposity indices and their higher predictive value for new-onset hypertension in metabolically healthy young women: findings from a population-based prospective cohort study BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-12 Rizki Amalia Gumilang, Yen-Chun Fan, Shang-Hao Wu, Chyi-Huey Bai
The present study aimed to investigate the predictive ability of selected adiposity indices, such as body mass index (BMI), waist-to-hip ratio (WHR), waist circumference (WC), and waist-to-height ratio (WHtR), for new-onset hypertension in metabolically healthy Taiwanese adults. The study also sought to establish sex-specific cutoff points for these indices and to analyze the risk of new-onset hypertension
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Risk stratification by systemic manifestations secondary to hemodynamic disorders of patients with severe tricuspid regurgitation BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-12 Xing-Yu Ji, Lei Zhu, Fei Chen, Fang-Lin Lu, Yuan Feng, Mao Chen, Tian-Yuan Xiong
Tricuspid regurgitation (TR) is a prevalent disease that triggers systemic pathological changes including cardiac, respiratory, hepatic and digestive, hematopoietic, renal and skin issues. The burden of extra-cardiac manifestations has not been well described in TR patients and the clinical impact is unknown. Patients with severe or more-than-severe TR during hospitalization, who did not have any previous
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Unlocking potential biomarkers bridging coronary atherosclerosis and pyrimidine metabolism-associated genes through an integrated bioinformatics and machine learning approach BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-07 Fanli Bu, Xiao Qin, Tiantian Wang, Na Li, Man Zheng, Zixuan Wu, Kai Ma
This study delves into the intricate landscape of atherosclerosis (AS), a chronic inflammatory disorder with significant implications for cardiovascular health. AS poses a considerable burden on global healthcare systems, elevating both mortality and morbidity rates. The pathological underpinnings of AS involve a marked metabolic disequilibrium, particularly within pyrimidine metabolism (PyM), a crucial
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The role of perioperative sedative anesthetics in preventing postoperative delirium: a systematic review and network-meta analysis including 6679 patients BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-06 Jin-Xiang Huang, Shan-Shan Zhang, Shu-Xian Wang, Da-Shuang Xi, Fang-Ru Luo, Cheng-Jiang Liu, Hong Li
Postoperative delirium is a common and debilitating complication that significantly affects patients and their families. The purpose of this study is to investigate whether there is an effective sedative that can prevent postoperative delirium while also examining the safety of using sedatives during the perioperative period. The net-meta analysis was used to compare the incidence of postoperative
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Contrasting the relationship of serum uric acid/albumin ratio on quantitative flow ratio with other multiple composite parameters in patients with suspected coronary artery disease BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-05 Jin Liu, Han Wei, Xuanzhi Zhu, Huangjun Liu, Lijun Jin
The aim of this study was to investigate the association between quantitative coronary flow reserve (CFR) and the blood uric acid/albumin ratio, as well as multiple clinical parameters, in order to assess the severity of coronary artery functional stenosis. This retrospective cross-sectional study included 257 suspected coronary artery disease patients who underwent coronary angiography (CAG) and quantitative
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Transvenous endocardial pacing with SelectSecure™ 3830 lead in pediatric patients: case series of two infants and a literature review BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-05 Chuan Yang, Jing Qi, Mahmood Alam, Deling Zou
The SelectSecure™ 3830 lead is an innovative, lumenless, and thin active fixed lead with a nonretractable screw-in tip and a diameter of 4.1 Fr, making it the thinnest pacing lead available. Its high anti-extrusion properties and durability have shown favorable outcomes in cardiac pacing, especially in pediatric patients. The superfine design and easy implantation of the lead have rendered it a preferred
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Prevalence, clinical features and prognosis of familial hypercholesterolemia in Chinese Han patients with acute coronary syndrome after a coronary event: a retrospective observational study BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-05 Huijuan Kou, Hongtao Wang, Peng Liu, Xin Wang, Wenjing Zhu, Wei Jiang, Xiaojun Hu, Jie Deng
Familial hypercholesterolemia (FH) is an autosomal semi-dominant disease, characterized by markedly elevated levels of low-density lipoprotein cholesterol (LDL-c) from conception and accelerated atherosclerotic cardiovascular disease, often resulting in early death. The aim of this study was to evaluate the prevalence of clinically defined FH in Chinese Han patients with acute coronary syndrome (ACS)
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Effectiveness of a tailored communication intervention to improve physical activity in hypertensive patients: a twelve-month randomized controlled trial BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-05 Roberta Adorni, Francesco Zanatta, Erika Rosa Cappelletti, Andrea Greco, Patrizia Steca, Marco D’Addario
Cardiovascular diseases (CVDs) are a leading cause of morbidity and mortality globally. Arterial hypertension is one of the main cardiovascular risk factors. Despite this, individuals with hypertension often fail to follow medical advice to counteract cardiovascular risks. A physically active lifestyle is one of the most challenging behaviors to adopt. This study aimed to preliminarily investigate
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Bioinformatics analysis of the microRNA genes associated with type 2 cardiorenal syndrome BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-05 Yani Zong, Yuexin Hu, Mengdi Zheng, Zhi Wang
MicroRNAs (miRNAs) are important regulatory factors in the normal developmental stages of the heart and kidney. However, it is currently unclear how miRNA is expressed in type 2 cardiorenal syndrome (CRS). This study aimed to detect the differential expression of miRNAs and to clarify the main enrichment pathways of differentially expressed miRNA target genes in type 2 CRS. Five cases of healthy control
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Global longitudinal strain and plasma biomarkers for prognosis in heart failure complicated by diabetes: a prospective observational study BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-05 Nithin R. Iyer, Siew-Pang Chan, Oi Wah Liew, Jenny P.C. Chong, Jennifer A. Bryant, Thu-Thao Le, Chanchal Chandramouli, Patrick J. Cozzone, Frank Eisenhaber, Roger Foo, A. Mark Richards, Carolyn S.P. Lam, Martin Ugander, Calvin W-L. Chin
Heart failure (HF) and diabetes are associated with increased incidence and worse prognosis of each other. The prognostic value of global longitudinal strain (GLS) measured by cardiovascular magnetic resonance (CMR) has not been established in HF patients with diabetes. In this prospective, observational study, consecutive patients (n = 315) with HF underwent CMR at 3T, including GLS, late gadolinium
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Age and healthy lifestyle behavior’s disparities and similarities on knowledge of myocardial infarction symptoms and risk factors among public and outpatients in a resource-limited setting, cross-sectional study in greater Gaborone, Botswana BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-04 Ookeditse Ookeditse, Kebadiretse K. Ookeditse, Thusego R. Motswakadikgwa, Gosiame Masilo, Yaone Bogatsu, Baleufi C. Lekobe, Mosepele Mosepele, Henrik Schirmer, Stein H. Johnsen
In this cross-sectional study from Botswana, we investigated knowledge of myocardial infarction (MI) symptoms and risk factors among the general public and outpatients with MI risk factors based on age and lifestyle behaviors, in addition to assessing associations with sociodemographic and MI risk factors. Open-ended questionnaires about 8 MI symptoms and 10 risk factors, were administered by research
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Safe and promising outcomes of in-hospital preoperative rehabilitation for coronary artery bypass grafting after an acute coronary syndrome BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-04 Ken Nakamura, Shusuke Arai, Kimihiro Kobayashi, Shingo Nakai, Ri Sho, Ai Ishizawa, Daisuke Watanabe, Shuto Hirooka, Eiichi Ohba, Masahiro Mizumoto, Yoshinori Kuroda, Cholsu Kim, Hideaki Uchino, Takao Shimanuki, Tetsuro Uchida
In patients with stable hemodynamic status after an acute coronary syndrome (ACS), coronary artery bypass grafting (CABG) after preoperative investigations can provide outcomes comparable to those of emergency surgery. However, no established guidelines exist regarding the preparation period before surgery. We report the results of the use of an inpatient cardiac rehabilitation program followed by
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Causality of the gut microbiome and atherosclerosis-related lipids: a bidirectional Mendelian Randomization study BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-02 Da Teng, Wenjuan Jia, Wenlong Wang, Lanlan Liao, Bowen Xu, Lei Gong, Haibin Dong, Lin Zhong, Jun Yang
Recent studies have indicated an association between intestinal flora and lipids. However, observational studies cannot indicate causality. In this study, we aimed to investigate the potentially causal relationships between the intestinal flora and blood lipids. We performed a bidirectional two-sample Mendelian Randomization (MR) analysis to investigate the causal relationship between intestinal flora
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Can prolonged P-R interval predict clinical outcomes in non-ST elevation acute coronary syndrome patients? BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-02 Mohammad Zareei, Hossein Zareiamand, Mahsa Kamali, Nasim Ardalani, Ata Ebrahimi, Maryam Nabati
The present study aimed to respond to clinical question, can prolonged P-R interval predict clinical outcomes in non-ST elevation acute coronary syndrome patients? This descriptive-analytical study was conducted on cardiac patients. All of the non-ST elevation acute coronary syndrome (NSTEACS) including non-ST elevation myocardial infarction (NSTEMI) and unstable angina patients included in the study
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Prognostic value of metabolic syndrome in patients with heart failure and malnutrition BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-02 Xuehe Zhang, Chunfang Shan, Kaixuan Hu, Binbin Fang, Zhiyang Zhang, Qian Xie, Chang Liu, Xin An, Yining Yang, Xiaomei Li
Malnutrition is severely associated with worst prognosis of patients with heart failure (HF). Malnourished patients with the metabolic syndrome (MS) can result in a double burden of malnutrition. We aimed to investigate the impact of the MS on clinical outcomes in malnourished HF patients. We examined 529 HF patients at risk of malnutrition with a mean age of (66 ± 10) years and 78% (415) were male
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Is Takotsubo syndrome induced by patent ductus arteriosus occlusion? BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-02 Shuhao Li, Senyan Yang, Shujing Zhou, Shuang Zhang, Xueying Li, Haibo Zhang, Ping Ren, Yanwu Liu, Ying Liu, Yuanguo Chen
Takotsubo syndrome (TTS), commonly referred to as "broken heart syndrome," is a distinctive form of acute and reversible heart failure that primarily affects young to middle-aged individuals, particularly women. While emotional or physical stressors often trigger TTS, rare cases have been linked to interventional procedures for congenital heart disease (CHD). Despite its recognition, the exact causes
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Correction to: Effect of sacubitril valsartan on heart failure with mid-range or preserved ejection fraction in patients on maintenance hemodialysis: real-world experience in a single-center, prospective study BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-02 Xiao-mei Huang, Jing-jing Li, Wang Yin, Hui-ling Fu, Fen Yu, Lian-qing Gu, Yi Zhang, Min Du, Zheng Ye, Li Xu
Correction to: BMC Cardiovascular Disorders (2024) 24:1 https://doi.org/10.1186/s12872-024-03744-y. Following publication of the original article [1], author Li Xu also should have been denoted as a corresponding author. The original article has been corrected. Huang X, Li J, Yin W, et al. Effect of sacubitril valsartan on heart failure with mid-range or preserved ejection fraction in patients on maintenance
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Association of prognostic nutritional index with peripheral artery disease in US adults: a cross-sectional study BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-03-02 Dikang Pan, Julong Guo, Zhixiang Su, Wenzhuo Meng, Jingyu Wang, Jianming Guo, Yongquan Gu
The objective of this study was to investigate the relationship between the prognostic nutritional index (PNI) and peripheral artery disease (PAD). The present study is a cross-sectional study based on the National Health and Nutrition Survey (1999–2004). The laboratory-calculated PNI was divided into four groups based on quartiles(Q1:PNI ≤ 50.00; Q2: 50.01–53.00; Q3:53.01–56.00; Q4: > 56.00). PAD
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Quality of life in young patients with acute type a aortic dissection in China: comparison with Marfan syndrome and non-Marfan syndrome BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-29 Xin-fan Lin, Lin-feng Xie, Zhao-feng Zhang, Jian He, Yu-ling Xie, Xiao-fu Dai, Liang-wan Chen
There is a paucity of Chinese studies evaluating the quality of life (QoL) in young acute type A aortic dissection (AAAD) patients with Marfan syndrome. Young adult AAAD patients (younger than 45 years old) underwent surgical treatment at our institution from January 2017 to December 2020 were consecutive enrolled. The hospital survivors completed 1 year of follow up. Patients were divided into two
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Catheter ablation versus medical therapy in atrial fibrillation: an umbrella review of meta-analyses of randomized clinical trials BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-29 Anoop Titus, Sakil Syeed, Abiram Baburaj, Karan Bhanushali, Pramod Gaikwad, Mannil Sooraj, Anu Mariam Saji, Wasey Ali Yadullahi Mir, Pramukh Arun Kumar, Mahati Dasari, Mubashir Ayaz Ahmed, Mohammed Omer Khan, Aishwarya Titus, Janamjey Gaur, Dilanthy Annappah, Arjun Raj, Nabeela Noreen, Adrian Hasdianda, Yasar Sattar, Bharat Narasimhan, Nishaki Mehta, Christopher V. Desimone, Abhishek Deshmukh, Sarju
This umbrella review synthesizes data from 17 meta-analyses investigating the comparative outcomes of catheter ablation (CA) and medical treatment (MT) for atrial fibrillation (AF). Outcomes assessed were mortality, risk of hospitalization, AF recurrence, cardiovascular events, pulmonary vein stenosis, major bleeding, and changes in left ventricular ejection fraction (LVEF) and MLHFQ score. The findings
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A rare case of an unexpected trigger of paroxysmal atrial fibrillation in the right atrial appendage diverticulum BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-29 Li Cheng, Jianbo Hu, Yuanping Zhang, Zhaohua Geng, Bo Zhang
We described a rare case of an adolescent girl with paroxysmal atrial fibrillation originating from the right atrial appendage diverticulum and successfully converted to sinus rhythm after surgical intervention. A 19-year-old girl was referred to the hospital for a catheter ablation of paroxysmal atrial fibrillation. conventional radiofrequency ablation using 3-D mapping were ineffective. Activation
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Risk factors for one-year mortality following discharge in patients with acute aortic dissection: development and validation of a predictive model in a cross-sectional study BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-29 Ting Zhou, Jing-Xiao Li, Chao-Yong Zhang, Yu-Gui Li, Jun Peng, Chun-Lou Wei, Meng-Hua Chen, Hua-Fu Zhou
This study was aimed to identify the risk factors that influence the mortality risk in patients with acute aortic dissection (AAD) within one year after discharge, and aimed to construct a predictive model for assessing mortality risk. The study involved 320 adult patients obtained from the Medical Information Mart for Intensive Care (MIMIC) database. Logistic regression analysis was conducted to identify
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Inhibition of valve mesenchymal stromal cell calcium deposition by bFGF through alternative polyadenylation regulation of the CAT gene BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-28 Jiajun Zhang, Jun Wu, Yuan Gao, Xingli Fan, Xiaohong Liu, Guanxin Zhang, Yangfeng Tang, Lin Han
Calcific aortic valve disease (CAVD) is the leading cause of angina, heart failure, and death from aortic stenosis. However, the molecular mechanisms of its progression, especially the complex disease-related transcriptional regulatory mechanisms, remain to be further elucidated. This study used porcine valvular interstitial cells (PVIC) as a model. We used osteogenic induced medium (OIM) to induce
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Social associations and cardiovascular mortality in the United States counties, 2016 to 2020 BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-26 Ashish Kumar, Kinza Iqbal, Mariam Shariff, Monil Majmundar, Ankur Kalra
The positive aspects of social interaction on health have been described often, with considerably less attention to their negative aspect. This study aimed to assess the impact of social associations on cardiovascular mortality in the United States. The Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) data sets from 2016 to 2020 were used to
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Macronutrients quality indices and risk of metabolic syndrome and its components in Iranian adults BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-26 Hossein Farhadnejad, Ebrahim Mokhtari, Farshad Teymoori, Mitra Kazemi Jahromi, Niloufar Saber, Hamid Ahmadirad, Mostafa Norouzzadeh, Parvin Mirmiran, Fereidoun Azizi
Evidence from recent studies suggested that the quality of dietary macronutrients can play a possible role in predicting the risk of metabolic disorders. In the current study, we aimed to assess the association of carbohydrate quality index (CQI) and protein score with the risk of metabolic syndrome (MetS) in Iranian adults. This prospective study was conducted within the framework of the Tehran Lipid
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Angiographic characteristics of coronary artery disease in patients undergoing diagnostic coronary angiography at a tertiary hospital in Tanzania BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-26 John R. Meda, Happiness L. Kusima, Ng’weina F. Magitta
Coronary artery disease (CAD) is an important cause of global burden of disease. There is a paucity of data on the burden and risk factors for CAD in sub-Saharan Africa (SSA), despite the rising trends in the shared risk factors across regions. The recent introduction of cardiac catheterization laboratory services in SSA could shed light on the burden of CAD in the region. We aimed to assess the angiographic
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Clinical comparative analysis of 3D printing-assisted extracorporeal pre-fenestration and Castor integrated branch stent techniques in treating type B aortic dissections with inadequate proximal landing zones BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-26 Rongyi Zheng, Huayuan Xi, Fangtao Zhu, Cunwei Cheng, Weihua Huang, Haojie Zhang, Xin He, KaiLin Shen, Ying Liu, QianQian Lu, Haibin Yu
This study aims to compare the clinical effects of two distinct surgical approaches, namely 3D printing-assisted extracorporeal pre-fenestration and Castor integrated branch stent techniques, in treating patients with Stanford type B aortic dissections (TBAD) characterized by inadequate proximal landing zones. A retrospective analysis was conducted on 84 patients with type B aortic dissection (TBAD)
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Integrated analysis and validation of ferroptosis-related genes and immune infiltration in acute myocardial infarction BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-24 Xinyu Wu, Jingru Li, Shengjie Chai, Chaguo Li, Si Lu, Suli Bao, Shuai Yu, Hao Guo, Jie He, Yunzhu Peng, Huang Sun, Luqiao Wang
Acute myocardial infarction (AMI) is indeed a significant cause of mortality and morbidity in individuals with coronary heart disease. Ferroptosis, an iron-dependent cell death, is characterized by the accumulation of intracellular lipid peroxides, which is implicated in cardiomyocyte injury. This study aims to identify biomarkers that are indicative of ferroptosis in the context of AMI, and to examine
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Semiquantitative 18F-FDG PET/CT in monitoring glucocorticoid response of immunoglobulin G4-related effusive constrictive pericarditis: a case report BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-22 Soo Yeon An, Byung Joo Sun
Immunoglobulin G4 (IgG4)-related effusive constrictive pericarditis (ECP) is a rare manifestation of IgG4-related disease (IgG4-RD). It can lead to persistent pericardial fibrosis, resulting in cardiac tamponade, diastolic dysfunction, and heart failure. Glucocorticoids are the primary treatment for effectively reducing inflammation and preventing fibrosis. However, guidelines for monitoring treatment
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Elucidating the mechanisms of formononetin in modulating atherosclerotic plaque formation in ApoE-/- mice BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-22 Ying He, Youde Cai, Dingling Wei, Liping Cao, Qiansong He, Yazhou Zhang
Atherosclerosis(AS) poses a pressing challenge in contemporary medicine. Formononetin (FMN) plays a crucial role in its prevention and treatment. However, the detailed impact of FMN on the stability of atherosclerotic plaques and its underlying mechanisms remain to be elucidated. An intervention consisting of FMN was given along with a high-fat food regimen in the ApoE-/- mouse model. The investigation
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Chinese Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (5A) Registry protocol: rationale, design and methodology BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-21 Hong Liu, Si-chong Qian, Hai-yang Li, Yong-feng Shao, Hong-jia Zhang
Acute aortic syndrome (AAS) is a life-threatening condition. Inflammation plays a key role in the pathogenesis, development and progression of AAS, and is associated with significant mortality and morbidity. Understanding the inflammatory responses and inflammation resolutions is essential for an appropriate management of AAS. Thirty Chinese cardiovascular centers have collaborated to create a multicenter
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Injectable hydrogel-based combination therapy for myocardial infarction: a systematic review and Meta-analysis of preclinical trials BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-21 Han Gao, Song Liu, Shanshan Qin, Jiali Yang, Tian Yue, Bengui Ye, Yue Tang, Jie Feng, Jun Hou, Dunzhu Danzeng
This study evaluates the effectiveness of a combined regimen involving injectable hydrogels for the treatment of experimental myocardial infarction. Myocardial infarction is an acute illness that negatively affects quality of life and increases mortality rates. Experimental models of myocardial infarction can aid in disease research by allowing for the development of therapies that effectively manage
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Analysis of the success rate of conversion using ibutilide administration in radiofrequency catheter ablation of persistent atrial fibrillation and its effects on postoperative recurrence BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-20 Meijuan Li, Xiping Liu, Yan Zhang, Weibin Huang, Bingbo Hou, Sen Huang, Feng Gao
To assess the efficacy of ibutilide administration during radiofrequency catheter ablation of persistent atrial fibrillation (AF), to explore the success rate of conversion and related influential factors, and to analyze the effects of ibutilide on postoperative recurrence. A total of 192 patients with persistent AF who underwent catheter ablation from January 1, 2019, to December 31, 2021. These patients
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The effect of personalized mobile health (mHealth) in cardiac rehabilitation for discharged elderly patients after acute myocardial infarction on their inner strength and resilience BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-19 Shahin Salarvand, Farzad Farzanpour, Hasan Ahmadi Gharaei
Given the importance of promoting self-care and quality of life for discharged elderly patients after acute Myocardial Infarction(MI), It is necessitated we conduct interventions to promote these items. This study was conducted to determine the effect of mHealth-Cardiac rehabilitation (CR) on the inner Strength and resilience of elderly patients with MI after discharge from the hospital. The present
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[D-Ala2, D-Leu5]-enkephalin (DADLE) provides protection against myocardial ischemia reperfusion injury by inhibiting Wnt/β-Catenin pathway BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-19 Linwen Liu, Yawu Sun, Yang Wang, Jun Xin, Wei Chen
Acute myocardial infarction is one of the leading causes of death worldwide. Myocardial ischemia reperfusion (MI/R) injury occurs immediately after the coronary reperfusion and aggravates myocardial ischemia. Whether the Wnt/β-Catenin pathway is involved in the protection against MI/R injury by DADLE has not been evaluated. Therefore, the present study aimed to investigate the protective effect of
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Long-term all-cause death prediction by coronary, aortic, and valvular calcification in patients with acute ST-segment elevation myocardial infarction BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-19 Yalin Cheng, Xuyang Meng, Haiyang Gao, Chenguang Yang, Peng Li, Hongfei Li, Saurav Chatterjee, Paulo Cury Rezende, Marc Bonnet, Huimin Li, Zunlei Zhang, Fusui Ji, Wenduo Zhang
To determine the prognostic value of cumulative calcification score of coronary artery calcification (CAC), thoracic aortic calcification (TAC) and aortic valve calcification (AVC) in acute ST segment elevation myocardial infarction (STEMI) patients. This was a retrospective, single-center cohort study. A total of 332 STEMI patients who received primary percutaneous coronary intervention (PPCI) were
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BRASH syndrome with a complete heart block- a case report BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-19 Habtamu Mesele Gebray, Abirham Eneyew Abeje, Abayneh Tunta Boye
BRASH syndrome (Bradycardia, Renal failure, Atrioventricular (AV) nodal blocking agent, Shock and Hyperkalemia) is a recently emerging diagnosis that describes the profound bradycardia seen in patients on AV nodal blockers who present with acute kidney injury (AKI) and hyperkalemia. We present a case of a 68 years old female patient with past history of hypertension taking atenolol and Enalapril presented
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Impact of body mass index on long-term outcomes in patients undergoing percutaneous coronary intervention stratified by diabetes mellitus: a retrospective cohort study BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-16 Chongyou Rao, Qin Zhong, Rilige Wu, Zongren Li, Yongjie Duan, You Zhou, Chi Wang, Xu Chen, Ruiqing Wang, Kunlun He
Patients with diabetes mellitus (DM) caused by obesity have increased in recent years. The impact of obesity on long-term outcomes in patients undergoing percutaneous coronary intervention (PCI) with or without DM remains unclear. We retrospectively analysed data from 1918 patients who underwent PCI. Patients were categorized into four groups based on body mass index (BMI, normal weight: BMI < 25 kg/m2;
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Prognostic value of native T1 and extracellular volume in patients with immunoglubin light-chain amyloidosis BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-16 Yumeng Liu, Lingjie Wang, Jingfen Zhu, Meng Chen, Mo Zhu, Yingyu Dai, Chunhong Hu
Cardiac involvement in patients with immunoglubin light-chain amyloidosis (AL) is a major determinant of treatment choice and prognosis, and early identification of high-risk patients can initiate intensive treatment strategies to achieve better survival. This study aimed to investigate the prognostic value of native T1 and ECV in patients with AL-cardiac amyloidosis (CA). A total of 38 patients (mean
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Association between baseline glycated hemoglobin level and atrial fibrillation recurrence following cryoballoon ablation among patients with and without diabetes BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-16 Zheng Chen, Ruixin Zhang, Xinlin Zhang, Wei Xu
The study aims to assess the effect of baseline glycated hemoglobin (HbA1c) levels on atrial fibrillation (AF) recurrence following cryoballoon ablation in patients with and without diabetes. Consecutive AF patients receiving first cryoballoon ablation between April 2018 and April 2021 were included. AF recurrence and other clinical outcomes were recorded for a minimum of 12 months post-ablation, with
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Frailty efficacy as a predictor of clinical and cognitive complications in patients undergoing coronary artery bypass grafting: a prospective cohort study BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-16 Mehrnoosh Bakhtiari, Farhad Shaker, Fatemeh Ojaghi Shirmard, Arash Jalali, Ahmad Vakili-Basir, Mohammad Balabandian, Sima Shamshiri Khamene, Izat Mohammadkhawajah, Akbar Shafiee, Seyedeh Zahra Badrkhahan, Kaveh Hosseini
Frailty is proposed as a predictor of outcomes in patients undergoing major surgeries, although data on the association of frailty and coronary artery bypass grafting (CABG) are lacking. We assessed the association between frailty and cognitive and clinical complications following CABG. This prospective study included patients aged over 60 years undergoing elective CABG at Tehran Heart Center from
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Serum fibroblast growth factor-2 levels complement vital biomarkers for diagnosing heart failure BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-15 Z. L. Yu, Z. H. Cai, J. T. Zheng, H. Y. Jiang, Y. Q. Zhou, N. K. Wong, H. B. Fu, X. B. Hong
Early diagnosis of atrial fibrillation is important as it is crucial for improving patient outcomes. Fibroblast growth factor-2 (FGF2) may serve as a diagnostic biomarker for heart failure due to its ability to promote cardiac fibrosis and hypertrophy; however, the relationship between FGF2 concentration and heart failure is unclear. Therefore, this study aimed to explore whether FGF2 could aid in
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Characteristics and outcome of patients with left atrial appendage closure in China: a single-center experience BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-14 Jingrui Zhang, Changyi Li, Lu Zhou, Caihua Sang, Songnan Li, Changsheng Ma
Clinical characteristics and long-term data on the safety and efficacy of LAAC in preventing cerebrovascular accident and thromboembolism among Chinese patients with non-valvular AF (NVAF) remain limited. Data of consecutive NVAF patients who underwent LAAC at Beijing Anzhen Hospital, Capital Medical University, from June 1, 2014, to December 31, 2021, were collected and analyzed retrospectively. The
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Serum zinc concentration in patients with myocardial infarction: a retrospective study BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-14 Atsushi Tanita, Shigeto Namiuchi, Kenta Onodera, Shinichiro Sunamura, Tsuyoshi Ogata, Kazuki Noda, Toru Takii
Zinc regulates the oxidative stress and inflammatory signaling cascade and affects the development and deterioration of cardiovascular disease. We investigated the prognosis of developing heart failure in patients with myocardial infarction. Patients with myocardial infarction (n = 243) were divided using the median value of zinc concentration on admission into low (< 66 µg/dL at admission, n = 111)
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Sacubitril/valsartan inhibits the proliferation of vascular smooth muscle cells through notch signaling and ERK1/2 pathway BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-14 Congfeng Xu, Ning Zhang, Hong Yuan, Liren Wang, Yonghong Li
To explore the role and mechanism of Notch signaling and ERK1/2 pathway in the inhibitory effect of sacubitril/valsartan on the proliferation of vascular smooth muscle cells (VSMCs). Human aortic vascular smooth muscle cells (HA-VSMCs) were cultured in vitro. The proliferating VSMCs were divided into three groups as control group, Ang II group and Ang II + sacubitril/valsartan group. Cell proliferation
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Annual evolution of the prescription of drugs with prognostic implications in acute decompensated heart failure with reduced ejection fraction BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-14 Raquel López-Vilella, Víctor DonosoTrenado, Borja Guerrero Cervera, Ignacio Sánchez-Lázaro, Luis Martínez Dolz, Luis Almenar Bonet
Quadruple therapy (renin angiotensin system inhibitors, beta-blockers, mineralocorticoid receptor antagonists and sodium/glucose cotransporter type 2 inhibitors [SGLT2i]) has become the current prognostic modifying treatment for heart failure (HF) with reduced ejection fraction (HFrEF). This study aimed to analyse the prescription´s evolution of this combination therapy, the analysis of each pharmacological
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Effect of mindfulness-based interventions on people with prehypertension or hypertension: a systematic review and meta-analysis of randomized controlled trials BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-14 Qiongshan Chen, Hui Liu, Shizheng Du
Hypertension and prehypertension have been widely recognized as the main contributors of global mortality. Evidence shows mindfulness-based interventions may reduce blood pressure and improve mental health. However, the effect of mindfulness-based interventions on blood pressure and mental health has not been fully understood. Potential studies published before May 24th 2023 were identified by searching
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Association between C10X polymorphism in the CARD8 gene and inflammatory markers in young healthy individuals in the LBA study BMC Cardiovasc. Disord. (IF 2.1) Pub Date : 2024-02-13 Karin Fransén, Ayako Hiyoshi, Geena V. Paramel, Anita Hurtig-Wennlöf
The Caspase activation and recruitment domain 8 (CARD8) protein is a component of innate immunity as a negative regulator of NF- ĸB, and has been associated with regulation of proteins involved in inflammation. Expression of CARD8 mRNA and protein has been identified in human atherosclerotic lesions, and the truncated T30A variant (rs2043211) of CARD8 has been associated with lower C-reactive (CRP)