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Expert Commentary on Hepatic Artery Infusion Pump Chemotherapy for Colorectal Liver Metastases. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-11-16 Skye C Mayo
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Laparoscopic Salvage Surgery for Infrarenal Para-aortic Lymph Node Recurrence of Rectal Cancer. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-11-16 Dong-Hee Na,An Na Seo,Soo Yeun Park
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Hepatic Artery Infusion Pump Chemotherapy for Colorectal Liver Metastases: What Does the Colorectal Surgeon Need to Know. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-11-16 Chi Zhang,Cornelius Thiels
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Loop Ileostomy Closure as a 23-Hour Stay Procedure With Preoperative Efferent Limb Enteral Stimulation: A Randomized Controlled Trial. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-11-16 Janyssa Charbonneau,Genevieve Morin,Xavier Paré,Jonathan Frigault,Sebastien Drolet,Alexandre Bouchard,François Rouleau-Fournier,Philippe Bouchard,Claude Thibault,François Letarte
BACKGROUND Loop ileostomy closure is a common procedure in colorectal surgery. Often seen as a simple operation associated with low complication rates, it still leads to lengthy hospitalizations. Reducing postoperative complications and ileus rates could lead to a shorter length of stay and even ambulatory surgery. OBJECTIVES This study aimed to assess the safety and feasibility of ileostomy closure
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Anastomotic Leakage in Relation to Type of Mesorectal Excision and Defunctioning Stoma Use in Anterior Resection for Rectal Cancer. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-11-16 Martin Rutegård,Johan Svensson,Josefin Segelman,Peter Matthiessen,Marie-Louise Lydrup,Jennifer Park,
BACKGROUND Anastomotic leakage after anterior resection for rectal cancer is more common after total compared to partial mesorectal excision but might be mitigated by a defunctioning stoma. OBJECTIVE The aim is to assess how anastomotic leakage is affected by type of mesorectal excision and defunctioning stoma use. DESIGN This is a retrospective multicenter cohort study evaluating anastomotic leakage
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Prediction of Pathologic Complete Response for Rectal Cancer Based on Pre-treatment Factors Using Machine Learning. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-11-16 Kevin A Chen,Paolo Goffredo,Logan R Butler,Chinmaya U Joisa,Jose G Guillem,Shawn M Gomez,Muneera R Kapadia
BACKGROUND Pathologic complete response after neoadjuvant therapy is an important prognostic indicator for locally advanced rectal cancer and may give insights into which patients might be treated nonoperatively in the future. Existing models for predicting pathologic complete response in the pre-treatment setting are limited by small datasets and low accuracy. OBJECTIVE We sought to use machine learning
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Usefulness of Transanal Minimally Invasive Intersphincteric Resection for Ultralow Rectal Cancer After Radical Prostatectomy. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-11-16 Hiroyuki Kuge,Fumikazu Koyama,Yosuke Iwasa,Takeshi Takei,Tadataka Takagi,Kosuke Fujimoto,Suzuka Harada,Masayuki Sho
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Development of a Diagnostic Artificial Intelligence Tool for Lateral Lymph Node Metastasis in Advanced Rectal Cancer. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-11-07 Kosuke Ozaki,Yusuke Kurose,Kazushige Kawai,Hirotoshi Kobayashi,Michio Itabashi,Yojiro Hashiguchi,Takuya Miura,Akio Shiomi,Tatsuya Harada,Yoichi Ajioka
BACKGROUND Metastatic lateral lymph node dissection can improve survival in patients with rectal adenocarcinoma, with or without chemoradiotherapy. However, the optimal imaging diagnostic criteria for lateral lymph node metastases remain undetermined. OBJECTIVE To develop a lateral lymph node metastasis diagnostic artificial intelligence tool using deep learning, for patients with rectal adenocarcinoma
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Sequential Lateral Lymphatic Metastasis Shows Similar Oncologic Outcomes to Upward Spread in Advanced Rectal Cancer After Preoperative Chemoradiotherapy. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-11-03 Hye Jin Kim,Gyu-Seog Choi,Seung Hyun Cho,Min Kyu Kang,Jun Seok Park,Soo Yeun Park,Byung Woog Kang,Jong Gwang Kim
BACKGROUND Whether lateral pelvic node metastasis should be considered as a regional or systemic disease is a longstanding debate. While previous Japanese studies have considered it to be locoregional disease, Western countries consider it a systemic disease and do not perform lateral pelvic node dissection after preoperative chemoradiotherapy. OBJECTIVES To evaluate whether lateral pelvic node metastasis
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Modified Approach for Extraperitoneal Colostomy Creation in Laparoscopic Abdominoperineal Resection. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-11-03 Xiang Zhang,Xin Li,Zhiqiang Cheng,Kexin Wang,Yong Dai,Yanlei Wang
BACKGROUND Parastomal hernia is a major long-term complication after abdominoperineal resection. Extraperitoneal colostomy has been proposed as an effective step for parastomal hernia prevention but it has not been widely used as it is technically-demanding and time-consuming. We proposed a modified approach for extraperitoneal colostomy creation by entering the extraperitoneal space through the arcuate
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Robotic Right Colectomy With Complete Mesocolic Excision, D3 Lymph Node Dissection and Intracorporeal Anastomosis. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-11-03 Ming-Yin Shen,Abraham Fingerhut
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Robotic Approach for Locally Advanced Rectal Cancer. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-11-03 Komal Yousaf,Mahmood Al-Dhaheri,Asma Ghallab,Amjad Parvaiz
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The Severity of Fecal Problems Is Negatively Associated With Quality of Life in a Non-Patient Dutch Population. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-11-02 Maaike B C Ten Hoor,Monika Trzpis,Paul M A Broens
BACKGROUND Constipation and fecal incontinence have a negative influence on quality of life. The association between the severity of fecal problems and quality of life has not been investigated in a non-patient population. OBJECTIVE To investigate the association between the severity of constipation and fecal incontinence and quality of life in non-patients. DESIGN A population-based, cross-sectional
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Fragility of Statistically Significant Outcomes in Colonic Diverticular Disease Randomized Trials: A Systematic Review. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-27 Tyler McKechnie,Shuling Yang,Kathy Wu,Sahil Sharma,Yung Lee,Lily Park,Edward Passos,Aristithes Doumouras,Dennis Hong,Sameer Parpia,Mohit Bhandari,Cagla Eskicioglu
BACKGROUND The p value has been criticized for an oversimplified determination of whether a treatment effect exists. One alternative is the fragility index. It is a representation of the minimum number of non-events that would need to be converted to events to increase the p value above 0.05. OBJECTIVE To determine the fragility index of randomized controlled trials assessing the efficacy of interventions
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Locoregional Recurrence in the RAPIDO Trial and the Importance of the Quality of the Resected Specimen: Does Surgical Resection Matter? Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-26 Francesco Marchegiani,Aleix Martinez-Pérez,Salvatore Pucciarelli,Nicola de'Angelis
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Mastering the Art of Addressing Feedback: Effective Response Strategies for Grant Critiques. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-26 Connie C Shao,Karin M Hardiman,Elizabeth Wick
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Comment on the RAPIDO Trial Point-Counterpoint Debate. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-26 Per J Nilsson,Boudewijn van Etten,Geke Ap Hospers,Corrie Am Marijnen,Elma Meershoek-Klein Kranenberg,Annet Gh Roodvoets,Cornelis Jh van de Velde,Bengt Glimelius
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Local Recurrence in Rectal Cancer: Small Absolute Numbers in a BIG Problem. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-26 Bruna B Vailati,Carlos Cerdán-Santacruz,Guilherme P São Julião,Leonardo Corbi,Rodrigo O Perez
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Take a Selfie: Optimizing Surgeon-Patient Interactions in Proctologic Disease Record-Keeping Among Gen Z and Millennial Patients. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-26 Cristopher Varela
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Reducing Carbon Footprint in Travel to the American Society of Colon and Rectal Surgeons Annual Meeting: Striking a Balance Between Environmental Impact and Collaborative Opportunities. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-26 Karen Trang,Benjamin S C Fung,Tyler Lamb,Husein Moloo,Elizabeth C Wick
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What's the Matter With Trials Today? Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-26 Scott E Regenbogen
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Management of Colorectal Cancer with Synchronous Liver Metastases. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-24 Jenna N Whitrock,Carla F Justiniano
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Expert Commentary on Management of Colorectal Cancer with Synchronous Liver Metastases. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-24 Oliver Peacock
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DCR: A World of Change and Strengthening Our Status. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-24 Susan Galandiuk
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The Impact of Prolonged Operative Time Associated with Minimally Invasive Colorectal Surgery: A Report from the Surgical Care Outcomes Assessment Program. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-23 Kenley R Unruh,Amir L Bastawrous,Shalini Kanneganti,Jennifer A Kaplan,Ravi Moonka,Laila Rashidi,Arthur Sillah,Vlad V Simianu
BACKGROUND Increased operative time in colorectal surgery is associated with worse surgical outcomes. Laparoscopic and robotic operations have improved outcomes, despite longer operative times. Further, the definition of "prolonged" operative time has not been consistently defined. OBJECTIVE The first objective was to define prolonged operative time across multiple colorectal operations and surgical
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Anal Monkeypox Disease: Description of 65 Cases. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-23 Benjamin Le Vavasseur,Sihem Bendaoud,Sarah Taieb,Beate Heym,Saliha Ysmael Dahlouk,Eloise Leclerc,Antonin Metaye,Bernard Bessanguem,Josée Bourguignon,Milad Taouk,Anne Gabarre,Stéphane Marot,Sarah Tepper,Olivier Lidove,Isabelle Etienney
BACKGROUND Monkeypox is a zoonosis endemic in Africa caused by three orthopoxvirus clades. Knowledge of the disease is limited, but a worldwide outbreak declared in April 2022 involving a new route of transmission. OBJECTIVE This study aimed to describe anal symptoms and outcomes in patients suffering from Monkeypox infection attending an emergency proctology unit in Paris. DESIGN This was an observational
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Sex-Based Differences in Inflammatory Bowel Disease Surgical Outcomes. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-23 Margaret H Sundel,John J Newland,Kyle W Blackburn,Roumen M Vesselinov,Samuel Eisenstein,Andrea C Bafford,
BACKGROUND Although there are discrepancies in the development and progression of inflammatory bowel disease based on biologic sex, little is known about differences in postoperative outcomes between men and women undergoing surgery for this condition. OBJECTIVE Our objective was to compare rates of anastomotic leaks, wound complications, and serious adverse events between men and women undergoing
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Surveillance and Management of Pouch Neoplasia in Familial Adenomatous Polyposis: A Systematic Review. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-23 Ophir Gilad,Hagit Tulchinsky,Revital Kariv
BACKGROUND Patients with familial adenomatous polyposis often require prophylactic colectomy with ileal pouch-anal anastomosis to treat and/or reduce to risk of colorectal neoplasia. However, after surgery, patients are still at some risk of developing pouch polyps and even cancer in both handsewn or stapled anastomoses. Management relies mainly on endoscopic or surgical interventions, while chemopreventive
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Development of a Polygenic Risk Score to Predict Diverticulitis. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-11 H David Schaeffer,Diane T Smelser,H Shanker Rao,Jeremy S Haley,Kevin C Long,Sasha H Slipak,David J Carey,Rebecca L Hoffman
BACKGROUND Despite its prevalence and associated morbidity, we remain limited in our ability to predict the course of a patient with diverticular disease. While several clinical and genetic risk factors have been identified, we do not know how these factors relate to one another. OBJECTIVE To determine if a polygenic risk score could improve risk prediction for diverticulitis and recurrent diverticulitis
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Prognostic Impact of Mucinous Adenocarcinoma in Stage II and III Colon Cancer. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-11 Seijong Kim,Jung Wook Huh,Woo Yong Lee,Seong Hyeon Yun,Hee Cheol Kim,Yong Beom Cho,Yoonah Park,Jung Kyong Shin
BACKGROUND Mucinous adenocarcinoma is a rare histologic feature of colorectal cancer and is characterized by oncologic features that are different from those of adenocarcinoma. However, there are conflicting views regarding the prognostic impact of mucinous adenocarcinoma on colon cancer. OBJECTIVE This study aimed to evaluate the prognostic impact of mucinous adenocarcinoma in stage II and III colon
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A Novel Machine Learning Approach to Predict Textbook Outcome in Colectomy. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-10 Amir Ashraf Ganjouei,Fernanda Romero-Hernandez,Patricia C Conroy,Phoebe Miller,Lucia Calthorpe,Jaeyun Jane Wang,Jackie Lin,Jean Feng,Kimberly S Kirkwood,Adnan Alseidi,Ankit Sarin,Mohamed A Adam
BACKGROUND Several calculators exist to predict risk of postoperative complications. However, in low-risk procedures such as colectomy, a tool to determine the probability of achieving the ideal outcome could better aid clinical decision making, especially for high-risk patients. A textbook outcome is a composite measure that serves as a surrogate for the ideal surgical outcome. OBJECTIVE To identify
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Validation of a Clinical Calculator Predicting Freedom from Colon Cancer Recurrence after Surgery on the Basis of Molecular and Clinical Variables. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-10 Asama Khan,Hannah Thompson,Meier Hsu,Maria Widmar,Iris H Wei,Emmanouil Pappou,J Joshua Smith,Garrett M Nash,Philip B Paty,Julio Garcia-Aguilar,Jinru Shia,Mithat Gonen,Martin R Weiser
BACKGROUND The Memorial Sloan Kettering clinical calculator for estimating the likelihood of freedom from colon cancer recurrence on the basis of clinical and molecular variables was developed at a time when testing for microsatellite instability was performed selectively, based on patient age, family history, and histologic features. Microsatellite stability was assumed if no testing was done. OBJECTIVE
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Risk Factors for Rectal Stump Leakage following Discontinuity Resection: Stump Length Matters Most. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-04 Alina S Ritter,Noemi Dumm,Julian M Deisenhofer,Clemens Franz,Mohammed Al-Saeedi,Markus W Büchler,Martin Schneider
BACKGROUND Discontinuity resection is commonly conducted to avoid anastomotic leakage in high-risk patients, but potentially results in rectal stump leakage. While risk factors for anastomotic leakage have been widely studied, data on rectal stump leakage rates and underlying risk factors are scarce. OBJECTIVE To determine rectal stump leakage rates following Hartmann's procedure and to identify patient-
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Combined Robotic Ventral Mesh Rectopexy and Sacrocolpopexy for Multicompartmental Pelvic Organ Prolapse. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-02 Liam Devane,Stacy Ranson,Leonardo Alfonso Bustamante-Lopez,Martin Uwah,Bela Kudish,Natha Kow,John Hoff,John R T Monson,Teresa deBeche-Adams
BACKGROUND Multispecialty management should be the preferred approach for the treatment of pelvic floor dysfunction, as there is often multicompartmental prolapse. OBJECTIVE To assess the safety of combined robotic ventral-mesh rectopexy and either uterine or vaginal fixation for treatment of multicompartmental pelvic organ prolapse at our institution. DESIGN Retrospective analysis. SETTINGS Tertiary
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The Theatre of Research in the Operating Room. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-10-02 Vladimir Bolshinsky
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Anal Cancers in Previously Screened Versus Unscreened Patients: Tumor Stage and Treatment Outcomes. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-09-26 Richard J B Walker,Alexandra M Easson,Ali Hosni,John Kim,Edward Weiss,Anna Theresa Santiago,Tyler R Chesney,Irving E Salit
BACKGROUND Targeted screening programs for patients at high risk for anal squamous cell carcinoma have been proposed; however, the evidence in support of screening remains unclear. OBJECTIVE This study aimed to determine whether screening high-risk patients (predominantly those living with HIV) detected squamous cell carcinoma at an earlier stage compared to the routine practice of not screening. DESIGN
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Clinical Experience of a Smart Articulating Digital Device for Transanal Minimally Invasive Surgery. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-09-25 Mohammad Faraz Khan,Emma Kearns,Ronan A Cahill
BACKGROUND The constrained access associated with transanal minimally invasive surgery has led surgeons to deploy robotic-assisted platforms to offset inherent maneuverability limitations and, perhaps, skills deficits. IMPACT OF INNOVATION A handheld, powered 5-mm lightweighted laparoendoscopic electromechanical digital device (HandX, HumanXtensions, Israel) with hardware and software components that
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A Novel Fluorescence-Based Leak Test Method for Rectal Anastomoses Using Aerosolized Indocyanine Green. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-09-25 Akihiro Kondo,Naoya Yokota,Nobuya Kobayashi,Dongping Feng,Eisuke Asano,Kensuke Kumamoto,Hideki Kobara,Keiichi Okano
BACKGROUND The intraoperative air leak test is commonly performed during rectal surgery to evaluate anastomotic integrity. However, its drawbacks include occasional difficulties in visualizing the exact point of the leak while maintaining the pelvis under saline, the need for repeat testing to identify the leak point, and a lack of continuous visualization of the leak point. OBJECTIVE We aimed to evaluate
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Challenges and Opportunities in the Elective Management of Diverticulitis: Perspectives from a National Sample of Colorectal Surgeons. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-09-25 Andrea J H Williamson,Brian T Cain,Trevor J Hoggan,Madison W Larsen,Elisabeth R Kimball,Kennedi Bloomquist,Patrick Galyean,Susan Zickmund,Jessica N Cohan
BACKGROUND Diverticulitis is a complex, heterogeneous disease process which affects a diverse population of patients. In the elective management of this disease, treatment guidelines have shifted toward patient-centered, individualized decision making. It is not known what challenges surgeons face as they approach these nuanced treatment decisions in practice. OBJECTIVE Identify opportunities to support
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Lateral Pelvic Nodal Management and Patterns of Failure in Patients Receiving Short-Course Radiation for Locally Advanced Rectal Cancer. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-09-25 Comron Hassanzadeh,Kasim Mirza,Bita Kalaghci,Fedra Fallahian,Re-I Chin,Amit Roy,Hayley Stowe,Gregory Low,Katrina Pedersen,Paul Wise,Sean Glasgow,Michael Roach,Lauren Henke,Shahed Badiyan,Matthew Mutch,Hyun Kim
BACKGROUND Management of lateral pelvic lymph nodes in locally advanced rectal cancer is controversial, with limited data indicating the optimal approach. Additionally, no data exists regarding treatment of lateral nodes in the setting of short course radiation and nonoperative intent. OBJECTIVE We evaluate a novel approach incorporating simultaneous integrated boost to suspicious lateral nodes. DESIGN
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The Long-term Outcomes of Sacral Neuromodulation for Fecal Incontinence: A Single Center Experience. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-09-21 Sarah Martin,Alexander D O'Connor,Deepak Selvakumar,Wal Baraza,Gemma Faulkner,Domini Mullins,Edward S Kiff,Karen Telford,Abhiram Sharma
BACKGROUND Sacral neuromodulation is an effective treatment for fecal incontinence. OBJECTIVE This study aimed to assess the long-term outcomes of sacral neuromodulation and establish the outcomes of patients with inactive devices. DESIGN This is an observational study of patients treated for more than 5 years. A positive outcome was defined as a >50% reduction in fecal incontinence episodes or improvement
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Direct Injection of Ex Vivo Expanded Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells for the Treatment of Pediatric Crohn's Perianal Fistulizing Disease. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-09-19 Amy L Lightner,Jacob Kurowski,Ana M Otero-Pinerio
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Assessing Guidelines on the Need for Colonoscopy after Initial Flexible Sigmoidoscopy in Young Patients with Outlet-Type Rectal Bleeding. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-09-14 Philip F Bagshaw,Anita Tuck,Jaana Aramowicz,Brian Cox,Francis Antony Frizelle,James M Church
BACKGROUND While young age of onset colorectal cancer is increasing in incidence lack of screening leads to symptomatic presentation, often with rectal bleeding. Because most cancers in patients under 50 are left-sided, flexible sigmoidoscopy is a reasonable way of investigating bleeding in these patients. OBJECTIVE To predict which patients undergoing flexible sigmoidoscopy for outlet rectal bleeding
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Postoperative Oral Rehydration and Regimented Follow-up Decrease Readmissions for Colorectal Surgery Patients with Ileostomies. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-09-12 Kristen M Westfall,Samantha J Rivard,Pasithorn A Suwanabol,Jeremy Albright,Carole Ramm,Robert K Cleary
BACKGROUND Ileostomies constitute 15-43% of readmissions after colorectal surgery, often due to dehydration and acute kidney injury. Prior institutional interventions decreased readmissions but not among patients with new ileostomies. OBJECTIVE Evaluate readmissions among patients with new ileostomies following postoperative oral rehydration solution and standardized clinic visits. DESIGN Retrospective
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The Prognostic Impact of Preoperative Osteopenia in Patients With Colorectal Cancer. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-09-12 Hirochika Kato,Ryo Seishima,Shodai Mizuno,Shimpei Matsui,Kohei Shigeta,Koji Okabayashi,Yuko Kitagawa
BACKGROUND Osteopenia, a condition in which bone mineral density is lower than normal, is a noted risk factor that leads to a shortened healthy life expectancy. OBJECTIVE To investigate the prognostic impact of preoperative osteopenia in patients with colorectal cancer. DESIGN This was a retrospective study. SETTING This study was conducted at a university hospital. PATIENTS A total of 1086 patients
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Specialty-Certified Colorectal Surgeons Demonstrate Favorable Short-term Surgical Outcomes for Laparoscopic Low Anterior Resection: Assessment of a Japanese Nationwide Database. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-09-11 Shigeki Yamaguchi,Hideki Endo,Hiroyuki Yamamoto,Toshiyuki Mori,Takeyuki Misawa,Masafumi Inomata,Hiroaki Miyata,Yoshihiro Kakeji,Yuko Kitagawa,Masahiko Watanabe,Yoshiharu Sakai
BACKGROUND There are few studies on the impact of a colorectal-specific technically certified surgeon on good surgical outcomes for laparoscopic low anterior resection in the real world. OBJECTIVE To evaluate the short-term outcomes of laparoscopic low anterior resection with the participation of a certified colorectal surgeon. DESIGN This was a retrospective cohort study using a Japanese nationwide
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M2 Macrophage-Derived Extracellular Vesicles Containing MicroRNA-501-3p Promote Colon Cancer Progression Through the SETD7/DNMT1/SOCS3 Axis. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-09-11 Yuanyi Ding,Huijin Zhao,Wenbo Niu,Juan Zhang,Xiaochuan Zheng,Youqiang Liu,Jianfeng Zhang,Chenhui Li,Bin Yu
BACKGROUND Macrophage-derived extracellular vesicles with microRNAs can cause and develop colon cancer. OBJECTIVE To investigate M2 macrophage-derived extracellular vesicles and colon cancer. DESIGN A prospective and experimental study of M2 macrophage-derived extracellular vesicles in colon cancer. SETTING This study was completed at the Fourth Hospital of Hebei Medical University. PATIENTS Patients
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Employment Status of Patients With Colorectal Cancer After Surgery: A Multicenter Prospective Cohort Study in Japan. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-09-08 Yusuke Fujita,Koya Hida,Takashi Sakamoto,Daisuke Nishizaki,Shiro Tanaka,Nobuaki Hoshino,Kae Okoshi,Ryo Matsusue,Takumi Imai,Kazutaka Obama
BACKGROUND Because of improved survival rates, patients with colorectal cancer may try to return to work. Many countries, however, have limited knowledge of the employment status of these patients. OBJECTIVE To explore the employment status of patients with colorectal cancer after surgery in Japan and the risk factors affecting the same. DESIGN This is a prospective multicenter cohort study that used
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A Longitudinal MRI-Based Artificial Intelligence System to Predict Pathological Complete Response After Neoadjuvant Therapy in Rectal Cancer: A Multicenter Validation Study. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-09-08 Jia Ke,Cheng Jin,Jinghua Tang,Haimei Cao,Songbing He,Peirong Ding,Xiaofeng Jiang,Hengyu Zhao,Wuteng Cao,Xiaochun Meng,Feng Gao,Ping Lan,Ruijiang Li,Xiaojian Wu
BACKGROUND Accurate prediction of response to neoadjuvant chemoradiotherapy is critical for subsequent treatment decisions for patients with locally advanced rectal cancer. OBJECTIVE To develop and validate a deep learning model based on the comparison of paired MRI before and after neoadjuvant chemoradiotherapy to predict pathological complete response. DESIGN By capturing the changes from MRI before
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Ureteral Stents Do Not Increase the Risk for Acute Kidney Injury after Colorectal Surgery. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-09-06 Isaac D Schmied,Dixy Rajkumar,Melissa I Chang,Sara M Colom,Robert K Cleary
BACKGROUND Ureteral stents are thought to prevent or help identify ureteral injuries. Studies suggesting that ureteral stents increase the risk of postoperative acute kidney injury show inconsistent conclusions. The large ureteral stenting volume at our institution provided a unique opportunity for granular analysis not previously reported. OBJECTIVE Determine if prophylactic ureteral stenting at colorectal
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Microsatellite Instability in Colorectal Cancer: The Evolving Role of Immunotherapy. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-09-06 Alexis D Desir,Fadwa G Ali
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Rectal Advancement Flap for a Rectal-Neovaginal Fistula. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-08-31 André Caiado,José Américo Hora,Carlos Frederico Marques
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Double-Barreled Wet Colostomy after Pelvic Exenteration. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-08-31 Hanna Cholewa,Jorge Sancho-Muriel,Blas Flor-Lorente
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Prospective Randomized Trial of Immediate Postoperative Use of Regular Diet Versus Clear Liquid Diet in Major Colorectal Surgery. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-08-31 Lucille Y Yao,Aimee E Gough,Karen N Zaghiyan,Phillip R Fleshner
BACKGROUND Enhanced recovery protocols are becoming standard practice after major colorectal surgery. An increasing body of evidence suggests that early feeding should be encouraged; however, whether a clear liquid diet or solid diet should be given immediately after surgery is undetermined. OBJECTIVE Evaluate whether regular diet was superior to clear liquid diet beginning on postoperative day 0 after
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The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Rectal Cancer 2023 Supplement. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-08-30 Sean J Langenfeld,Bradley R Davis,Jon D Vogel,Jennifer S Davids,Larissa K F Temple,Kyle G Cologne,Samantha Hendren,Steven Hunt,Julio Garcia Aguilar,Daniel L Feingold,Amy L Lightner,Ian M Paquette,
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Robotic Rectosigmoidopexy for Recurrent External Prolapse After Altemeier Procedure. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-08-30 Daniele Zigiotto,Alessandro Sturiale,Gabriele Naldini
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Intraoperative Laparoscopic Fixation Sutures to Prevent Neorectal Prolapse after Transanal Total Mesorectal Excision. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-08-30 Simona Ascanelli,Daniele Marcello,Giorgio Soliani,Carlo Feo,Alessandro De Troia,Alberto Campagnaro,Paolo Carcoforo
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Identification of MKI67, TPR , and TCHH Mutations as Prognostic Biomarkers for Patients With Defective Mismatch Repair Colon Cancer Stage II/III. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-08-29 Jingfang Lv,Wenbin Li,Xintong Wang,Lei Guo,Dongliang Wang,Yiran Zhang,Jun Yu,Tianli Chen,Beifang Niu,Xishan Wang,Zheng Liu
BACKGROUND Stage II/III disease is the most predominant form of colorectal cancer, accounting for approximately 70% of cases. Furthermore, approximately 15% to 20% of patients with stage II/III disease have deficient mismatch repair or microsatellite instability-high colorectal cancer. However, there are no identified significant prognostic biomarkers for this disease. OBJECTIVE To identify prognostic
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Excisional Hemorrhoidectomy Versus Dearterialization With Mucopexy for the Treatment of Grade III Hemorrhoidal Disease: The EMODART3 Multicenter Study. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-08-24 Antonio Giuliani,Lucia Romano,Stefano Necozione,Vincenza Cofini,Giada Di Donato,Mario Schietroma,Francesco Carlei,
BACKGROUND Over the past few decades, several surgical approaches have been proposed to treat hemorrhoids. OBJECTIVE This multicenter study aimed to compare transanal hemorrhoidal artery ligation and conventional excisional hemorrhoidectomy for grade III hemorrhoidal disease. DESIGN Multicenter retrospective study. SETTINGS Any center belonging to the Italian Society of Colorectal Surgery in which
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TAMIS Procedure for Rectal Neuroendocrine Tumor: Step by Step. Dis. Colon Rectum (IF 3.9) Pub Date : 2023-08-23 Mahmood Al Dhaheri,Reem Mubarak,Mohamed Kurer