样式: 排序: IF: - GO 导出 标记为已读
-
Urea breath test for Helicobacter pylori infection in adult dyspeptic patients: A meta-analysis of diagnostic test accuracy. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-3-11 Fabian Fellipe Bueno Lemos, Caroline Tianeze de Castro, Marcel Silva Luz, Gabriel Reis Rocha, Gabriel Lima Correa Santos, Luís Guilherme de Oliveira Silva, Mariana Santos Calmon, Cláudio Lima Souza, Ana Carla Zarpelon-Schutz, Kádima Nayara Teixeira, Dulciene Maria de Magalhães Queiroz, Fabrício Freire de Melo
Helicobacter pylori (H. pylori) infection has been well-established as a significant risk factor for several gastrointestinal disorders. The urea breath test (UBT) has emerged as a leading non-invasive method for detecting H. pylori. Despite numerous studies confirming its substantial accuracy, the reliability of UBT results is often compromised by inherent limitations. These findings underscore the
-
Y-Z deformable magnetic ring for the treatment of rectal stricture: A case report and review of literature. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-3-11 Miao-Miao Zhang, Huan-Chen Sha, Yuan-Fa Qin, Yi Lyu, Xiao-Peng Yan
Treatment of postoperative anastomotic stenosis for colorectal cancer is often challenging, especially for patients who do not respond well to endoscopy. In cases where patients have undergone an enterostomy, the stenosis can be easily resolved through magnetic compression. However, common magnetic compression techniques cannot be performed on those without enterostomy. We designed a novel Y-Z deformable
-
Diagnostic tools for fecal incontinence: Scoring systems are the crucial first step. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-3-11 Peter Liptak, Martin Duricek, Peter Banovcin
The main aim of this editorial is to comment on the recent article published by Garg et al in the World Journal of Gastroenterology 2023; 29: 4593-4603. This original research presents a new scoring system for fecal incontinence. Fecal incontinence is a chronic disease with a severe impact on the quality of life of the patients. Substantial social stigmatization often leads to significant underreporting
-
Emerging role of exosomes in ulcerative colitis: Targeting NOD-like receptor family pyrin domain containing 3 inflammasome. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-3-11 Xin Li, Li-Jiang Ji, Kai-Di Feng, Hua Huang, Mei-Rou Liang, Shi-Jin Cheng, Xiu-Dong Meng
Ulcerative colitis (UC) is a chronic recurrent inflammatory bowel disease. Despite ongoing advances in our understanding of UC, its pathogenesis is yet unelucidated, underscoring the urgent need for novel treatment strategies for patients with UC. Exosomes are nanoscale membrane particles that mediate intercellular communication by carrying various bioactive molecules, such as proteins, RNAs, DNA,
-
Preoperative prediction of lymphovascular and perineural invasion in gastric cancer using spectral computed tomography imaging and machine learning. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-3-11 Hui-Ting Ge, Jian-Wu Chen, Li-Li Wang, Tian-Xiu Zou, Bin Zheng, Yuan-Fen Liu, Yun-Jing Xue, Wei-Wen Lin
Lymphovascular invasion (LVI) and perineural invasion (PNI) are important prognostic factors for gastric cancer (GC) that indicate an increased risk of metastasis and poor outcomes. Accurate preoperative prediction of LVI/PNI status could help clinicians identify high-risk patients and guide treatment decisions. However, prior models using conventional computed tomography (CT) images to predict LVI
-
Angiotensin-converting enzyme 2 alleviates liver fibrosis through the renin-angiotensin system. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-3-11 Bai-Wei Zhao, Ying-Jia Chen, Ruo-Peng Zhang, Yong-Ming Chen, Bo-Wen Huang
The present letter to the editor is related to the study titled 'Angiotensin-converting enzyme 2 improves liver fibrosis in mice by regulating autophagy of hepatic stellate cells'. Angiotensin-converting enzyme 2 can alleviate liver fibrosis by regulating autophagy of hepatic stellate cells and affecting the renin-angiotensin system.
-
Endoscopic intramural cystogastrostomy for treatment of peripancreatic fluid collection: A viewpoint from a surgeon. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-3-11 Chen-Guo Ker
Percutaneous or endoscopic drainage is the initial choice for the treatment of peripancreatic fluid collection in symptomatic patients. Endoscopic transgastric fenestration (ETGF) was first reported for the management of pancreatic pseudocysts of 20 patients in 2008. From a surgeon's viewpoint, ETGF is a similar procedure to cystogastrostomy in that they both produce a wide outlet orifice for the drainage
-
Optimized sequential therapy vs 10- and 14-d concomitant therapy for eradicating Helicobacter pylori: A randomized clinical trial. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-3-11 Hassan Seddik, Jihane Benass, Sanaa Berrag, Asmae Sair, Reda Berraida, Hanae Boutallaka
A cure for Helicobacter pylori (H. pylori) remains a problem of global concern. The prevalence of antimicrobial resistance is widely rising and becoming a challenging issue worldwide. Optimizing sequential therapy seems to be one of the most attractive strategies in terms of efficacy, tolerability and cost. The most common sequential therapy consists of a dual therapy [proton-pump inhibitors (PPIs)
-
Unmet needs in biomarkers for autoimmune pancreatitis diagnosis. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-3-11 Bao-Can Wang, Jian-Gao Fan
Autoimmune pancreatitis (AIP) is a rare chronic autoimmune disorder. The diagnosis of AIP mainly depends on histopathology, imaging and response to treatment. Serum immunoglobulin 4 (IgG4) is used only as collateral evidence in diagnostic criteria for AIP because of its moderate sensitivity. Serum IgG4 levels are normal in 15%-37% of type 1 AIP and most of type 2 AIP patients. In these patients, the
-
Role of deubiquitinase JOSD2 in the pathogenesis of esophageal squamous cell carcinoma. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-3-11 Wen-Peng Wang, Dan Shi, Duo Yun, Jun Hu, Jie-Fu Wang, Jia Liu, Yan-Peng Yang, Ming-Rui Li, Jun-Feng Wang, Da-Lu Kong
Esophageal squamous cell carcinoma (ESCC) is a deadly malignancy with limited treatment options. Deubiquitinases (DUBs) have been confirmed to play a crucial role in the development of malignant tumors. JOSD2 is a DUB involved in controlling protein deubiquitination and influencing critical cellular processes in cancer.
-
Evaluation of the efficacy and safety of endoscopic band ligation in the treatment of bleeding from mild to moderate gastric varices type 1. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-28 Yue Deng, Ya Jiang, Tong Jiang, Ling Chen, Hai-Jun Mou, Bi-Guang Tuo, Guo-Qing Shi
According to practice guidelines, endoscopic band ligation (EBL) and endoscopic tissue adhesive injection (TAI) are recommended for treating bleeding from esophagogastric varices. However, EBL and TAI are known to cause serious complications, such as hemorrhage from dislodged ligature rings caused by EBL and hemorrhage from operation-related ulcers resulting from TAI. However, the optimal therapy for
-
Prevention of hepatitis B reactivation in patients with hematologic malignancies treated with novel systemic therapies: Who and Why? World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-28 Matteo Tonnini, Clara Solera Horna, Luca Ielasi
The risk of reactivation in patients with chronic or past/resolved hepatitis B virus (HBV) infection receiving chemotherapy or immunosuppressive drugs is a well-known possibility. The indication of antiviral prophylaxis with nucleo(t)side analogue is given according to the risk of HBV reactivation of the prescribed therapy. Though the advent of new drugs is occurring in all the field of medicine, in
-
Nicotinamide adenine dinucleotide phosphate oxidase in pancreatic diseases: Mechanisms and future perspectives. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-28 Ya-Wei Bi, Long-Song Li, Nan Ru, Bo Zhang, Xiao Lei
Pancreatitis and pancreatic cancer (PC) stand as the most worrisome ailments affecting the pancreas. Researchers have dedicated efforts to unraveling the mechanisms underlying these diseases, yet their true nature continues to elude their grasp. Within this realm, oxidative stress is often believed to play a causal and contributory role in the development of pancreatitis and PC. Excessive accumulation
-
Development and validation of a prediction model for early screening of people at high risk for colorectal cancer. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-28 Ling-Li Xu, Yi Lin, Li-Yuan Han, Yue Wang, Jian-Jiong Li, Xiao-Yu Dai
Colorectal cancer (CRC) is a serious threat worldwide. Although early screening is suggested to be the most effective method to prevent and control CRC, the current situation of early screening for CRC is still not optimistic. In China, the incidence of CRC in the Yangtze River Delta region is increasing dramatically, but few studies have been conducted. Therefore, it is necessary to develop a simple
-
Recombinant adeno-associated virus 8-mediated inhibition of microRNA let-7a ameliorates sclerosing cholangitis in a clinically relevant mouse model. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-28 Hui Hua, Qian-Qian Zhao, Miriam Nkesichi Kalagbor, Guo-Zhi Yu, Man Liu, Zheng-Rui Bian, Bei-Bei Zhang, Qian Yu, Yin-Hai Xu, Ren-Xian Tang, Kui-Yang Zheng, Chao Yan
Primary sclerosing cholangitis (PSC) is characterized by chronic inflammation and it predisposes to cholangiocarcinoma due to lack of effective treatment options. Recombinant adeno-associated virus (rAAV) provides a promising platform for gene therapy on such kinds of diseases. A microRNA (miRNA) let-7a has been reported to be associated with the progress of PSC but the potential therapeutic implication
-
Leveraging machine learning for early recurrence prediction in hepatocellular carcinoma: A step towards precision medicine. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-28 Abhimati Ravikulan, Kamran Rostami
The high rate of early recurrence in hepatocellular carcinoma (HCC) post curative surgical intervention poses a substantial clinical hurdle, impacting patient outcomes and complicating postoperative management. The advent of machine learning provides a unique opportunity to harness vast datasets, identifying subtle patterns and factors that elude conventional prognostic methods. Machine learning models
-
Can serum immunoglobulin G4 levels and age serve as reliable predictors of relapse in autoimmune pancreatitis? World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-28 Jun-Min Song, Si-Yu Sun
We are writing in response to the paper published in the World Journal of Gastroenterology by Zhou et al. The authors identified higher serum immunoglobulin (Ig) G4 levels and age over 55 years as independent risk factors for disease relapse. Despite notable strengths, it is crucial to address potential biases. Firstly, the cohort study included 189 patients with autoimmune pancreatitis (AIP) type
-
Diagnosis and treatment experience of atypical hepatic cystic echinococcosis type 1 at a tertiary center in China. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-28 Yu-Peng Li, Jie Zhang, Zhi-De Li, Chao Ma, Guang-Lei Tian, Yuan Meng, Xiong Chen, Zhi-Gang Ma
Some hydatid cysts of cystic echinococcosis type 1 (CE1) lack well-defined cyst walls or distinctive endocysts, making them difficult to differentiate from simple hepatic cysts.
-
Bile acids inhibit ferroptosis sensitivity through activating farnesoid X receptor in gastric cancer cells. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-28 Chu-Xuan Liu, Ying Gao, Xiu-Fang Xu, Xin Jin, Yun Zhang, Qian Xu, Huan-Xin Ding, Bing-Jun Li, Fang-Ke Du, Lin-Chuan Li, Ming-Wei Zhong, Jian-Kang Zhu, Guang-Yong Zhang
Gastric cancer (GC) is associated with high mortality rates. Bile acids (BAs) reflux is a well-known risk factor for GC, but the specific mechanism remains unclear. During GC development in both humans and animals, BAs serve as signaling molecules that induce metabolic reprogramming. This confers additional cancer phenotypes, including ferroptosis sensitivity. Ferroptosis is a novel mode of cell death
-
Dynamic ultrasonography for optimizing treatment position in superior mesenteric artery syndrome: Two case reports and review of literature. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-28 Nobuaki Hasegawa, Akihiko Oka, Muyiwa Awoniyi, Yuri Yoshida, Hiroshi Tobita, Norihisa Ishimura, Shunji Ishihara
Superior mesenteric artery (SMA) syndrome is a rare cause of duodenal obstruction by extrinsic compression between the SMA and the aorta (SMA-Ao). Although the left lateral recumbent position is considered effective in the treatment of SMA syndrome, individual variations in the optimal patient position have been noted. In this report, we present two elderly cases of SMA syndrome that exhibited rapid
-
Small nucleolar RNA and its potential role in the oncogenesis and development of colorectal cancer. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Yang-Zheng Lan, Zheng Wu, Wen-Jia Chen, Ze-Xuan Fang, Xin-Ning Yu, Hua-Tao Wu, Jing Liu
Small nucleolar RNAs (snoRNAs) represent a class of non-coding RNAs that play pivotal roles in post-transcriptional RNA processing and modification, thereby contributing significantly to the maintenance of cellular functions related to protein synthesis. SnoRNAs have been discovered to possess the ability to influence cell fate and alter disease progression, holding immense potential in controlling
-
Long-term prognosis and its associated predictive factors in patients with eosinophilic gastroenteritis. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Kai-Wen Li, Ge-Chong Ruan, Shuang Liu, Tian-Ming Xu, Ye Ma, Wei-Xun Zhou, Wei Liu, Peng-Yu Zhao, Zhi-Rong Du, Ji Li, Jing-Nan Li
Eosinophilic gastroenteritis (EGE) is a chronic recurrent disease with abnormal eosinophilic infiltration in the gastrointestinal tract. Glucocorticoids remain the most common treatment method. However, disease relapse and glucocorticoid dependence remain notable problems. To date, few studies have illuminated the prognosis of EGE and risk factors for disease relapse.
-
Gastric cancer immunotherapy: A scientometric and clinical trial review. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Qian-Cheng Du, Xin-Yu Wang, Hua Yu
This letter is intended to arouse your interest in a recent review of comprehensive scientometrics and clinical trials on immunotherapy for gastric cancer (GC). Our study reviews recent advances in immunotherapy in the field of GC and highlights its new prospects as a treatment for GC. Our research reveals China's leadership in this field, as well as new therapeutic strategies such as immune checkpoint
-
Esophageal intramural pseudodiverticulosis. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Masako Shintaku
Esophageal intramural pseudodiverticulosis (EIPD) is a disease of unknown pathogenesis characterized by usually systemic, cystic dilatation of the excretory ducts of esophageal submucosal glands. In this article, I review the epidemiology, clinical manifestations, endoscopic findings, esophagographic findings, and histopathology of EIPD. I also discuss the etiology and possible pathogenesis of EIPD
-
Hepatocardiorenal syndrome in liver cirrhosis: Recognition of a new entity? World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Henry H L Wu, Amina Rakisheva, Arvind Ponnusamy, Rajkumar Chinnadurai
Emerging evidence and perspectives have pointed towards the heart playing an important role in hepatorenal syndrome (HRS), outside of conventional understanding that liver cirrhosis is traditionally considered the sole origin of a cascade of pathophysiological mechanisms directly affecting the kidneys in this context. In the absence of established heart disease, cirrhotic cardiomyopathy may occur more
-
Success of susceptibility-guided eradication of Helicobacter pylori in a region with high secondary clarithromycin and levofloxacin resistance rates. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Yan-Meng Wang, Mo-Ye Chen, Jing Chen, Xin-He Zhang, Yan Feng, Yu-Xi Han, Yi-Ling Li
Resistance to clarithromycin (CLA) and levofloxacin (LFX) of Helicobacter pylori (H. pylori) is increasing in severity, and successful eradication is essential. Presently, the eradication success rate has greatly declined, leaving a large number of patients with previous treatment histories.
-
Association of tumor budding with clinicopathological features and prognostic value in stage III-IV colorectal cancer. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Yue-Hao Luo, Zhe-Cheng Yan, Jia-Ying Liu, Xin-Yi Li, Ming Yang, Jun Fan, Bo Huang, Cheng-Gong Ma, Xiao-Na Chang, Xiu Nie
Tumor budding (TB) has emerged as a promising independent prognostic biomarker in colorectal cancer (CRC). The prognostic role of TB has been extensively studied and currently affects clinical decision making in patients with stage I and II CRC. However, existing prognostic studies on TB in stage III CRC have been confined to small retrospective cohort studies. Consequently, this study investigated
-
Automatic detection of small bowel lesions with different bleeding risks based on deep learning models. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Rui-Ya Zhang, Peng-Peng Qiang, Ling-Jun Cai, Tao Li, Yan Qin, Yu Zhang, Yi-Qing Zhao, Jun-Ping Wang
Deep learning provides an efficient automatic image recognition method for small bowel (SB) capsule endoscopy (CE) that can assist physicians in diagnosis. However, the existing deep learning models present some unresolved challenges.
-
Hepatic arterial infusion chemotherapy with anti-angiogenesis agents and immune checkpoint inhibitors for unresectable hepatocellular carcinoma and meta-analysis. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Yu-Zhe Cao, Guang-Lei Zheng, Tian-Qi Zhang, Hong-Yan Shao, Jia-Yu Pan, Zi-Lin Huang, Meng-Xuan Zuo
Hepatic arterial infusion chemotherapy (HAIC) has been proven to be an ideal choice for treating unresectable hepatocellular carcinoma (uHCC). HAIC-based treatment showed great potential for treating uHCC. However, large-scale studies on HAIC-based treatments and meta-analyses of first-line treatments for uHCC are lacking.
-
Current status of magnetic resonance imaging radiomics in hepatocellular carcinoma: A quantitative review with Radiomics Quality Score. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Valentina Brancato, Marco Cerrone, Nunzia Garbino, Marco Salvatore, Carlo Cavaliere
Radiomics is a promising tool that may increase the value of magnetic resonance imaging (MRI) for different tasks related to the management of patients with hepatocellular carcinoma (HCC). However, its implementation in clinical practice is still far, with many issues related to the methodological quality of radiomic studies.
-
Revolutionizing gastric cancer treatment: The potential of immunotherapy. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Grigorios Christodoulidis, Konstantinos Eleftherios Koumarelas, Marina Nektaria Kouliou
Gastric cancer, a prevalent malignancy worldwide, ranks sixth in terms of frequency and third in fatality, causing over a million new cases and 769000 annual deaths. Predominant in Eastern Europe and Eastern Asia, risk factors include family medical history, dietary habits, tobacco use, Helicobacter pylori, and Epstein-Barr virus infections. Unfortunately, gastric cancer is often diagnosed at an advanced
-
Circulating microRNA expression and nonalcoholic fatty liver disease in adolescents with severe obesity. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Yi-Jie Li, Brittney O Baumert, Nikos Stratakis, Jesse A Goodrich, Hao-Tian Wu, Jing-Xuan He, Yin-Qi Zhao, Max T Aung, Hong-Xu Wang, Sandrah P Eckel, Douglas I Walker, Damaskini Valvi, Michele A La Merrill, Justin R Ryder, Thomas H Inge, Todd Jenkins, Stephanie Sisley, Rohit Kohli, Stavra A Xanthakos, Andrea A Baccarelli, Rob McConnell, David V Conti, Lida Chatzi
Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases in children and adolescents. NAFLD ranges in severity from isolated hepatic steatosis to nonalcoholic steatohepatitis (NASH), wherein hepatocellular inflammation and/or fibrosis coexist with steatosis. Circulating microRNA (miRNA) levels have been suggested to be altered in NAFLD, but the extent to which miRNA
-
Leukocyte immunoglobulin-like receptor B2: A promising biomarker for colorectal cancer. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Wen-Zhuo Zhao, Hong-Gang Wang, Xiao-Zhong Yang
According to the latest global cancer statistics, colorectal cancer (CRC) has emerged as the third most prevalent malignant tumor across the globe. In recent decades, the medical field has implemented several levels of CRC screening tests, encompassing fecal tests, endoscopic examinations, radiological examinations and blood tests. Previous studies have shown that leukocyte immunoglobulin-like receptor
-
Antiviral treatment standards for hepatitis B: An urgent need for expansion. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Zi-Hong Bao, Zhi-Kun Dai, Hao-Xian Tang
The present letter to the editor is related to the review with the title "Past, present, and future of long-term treatment for hepatitis B virus." Chronic hepatitis B (CHB) represents an important and pressing public health concern. Timely identification and effective antiviral therapy hold the potential to reduce liver-related mortality attributable to chronic infection with hepatitis B virus (HBV)
-
Portal hypertension in patients with nonalcoholic fatty liver disease: Current knowledge and challenges. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Anita Madir, Ivica Grgurevic, Emmanuel A Tsochatzis, Massimo Pinzani
Portal hypertension (PH) has traditionally been observed as a consequence of significant fibrosis and cirrhosis in advanced non-alcoholic fatty liver disease (NAFLD). However, recent studies have provided evidence that PH may develop in earlier stages of NAFLD, suggesting that there are additional pathogenetic mechanisms at work in addition to liver fibrosis. The early development of PH in NAFLD is
-
Value of multiple models of diffusion-weighted imaging to predict hepatic lymph node metastases in colorectal liver metastases patients. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Hai-Bin Zhu, Bo Zhao, Xiao-Ting Li, Xiao-Yan Zhang, Qian Yao, Ying-Shi Sun
About 10%-31% of colorectal liver metastases (CRLM) patients would concomitantly show hepatic lymph node metastases (LNM), which was considered as sign of poor biological behavior and a relative contraindication for liver resection. Up to now, there's still lack of reliable preoperative methods to assess the status of hepatic lymph nodes in patients with CRLM, except for pathology examination of lymph
-
Amlodipine inhibits the proliferation and migration of esophageal carcinoma cells through the induction of endoplasmic reticulum stress. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Yan-Min Chen, Wen-Qian Yang, Cheng-Wei Gu, Ying-Ying Fan, Yu-Zhen Liu, Bao-Sheng Zhao
L-type calcium channels are the only protein channels sensitive to calcium channel blockers, and are expressed in various cancer types. The Cancer Genome Atlas database shows that the mRNA levels of multiple L-type calcium channel subunits in esophageal squamous cell carcinoma tumor tissue are significantly higher than those in normal esophageal epithelial tissue. Therefore, we hypothesized that amlodipine
-
Gastrointestinal manifestations of critical ill heatstroke patients and their associations with outcomes: A multicentre, retrospective, observational study. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Yu-Cong Wang, Xin-Yang Jin, Zheng Lei, Xiao-Jiao Liu, Yu Liu, Bang-Guo Zhang, Jian Gong, Lie-Tao Wang, Lv-Yuan Shi, Ding-Yuan Wan, Xin Fu, Lu-Ping Wang, Ai-Jia Ma, Yi-Song Cheng, Jing Yang, Min He, Xiao-Dong Jin, Yan Kang, Bo Wang, Zhong-Wei Zhang, Qin Wu
Extreme heat exposure is a growing health problem, and the effects of heat on the gastrointestinal (GI) tract is unknown. This study aimed to assess the incidence of GI symptoms associated with heatstroke and its impact on outcomes.
-
Calcium/calcimimetic via calcium-sensing receptor ameliorates cholera toxin-induced secretory diarrhea in mice. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Lie-Qi Tang, Johnathan Fraebel, Shi Jin, Steven P Winesett, Jane Harrell, Wen-Han Chang, Sam Xianjun Cheng
Enterotoxins produce diarrhea through direct epithelial action and indirectly by activating the enteric nervous system. Calcium-sensing receptor (CaSR) inhibits both actions. The latter has been well documented in vitro but not in vivo. The hypothesis to be tested was that activating CaSR inhibits diarrhea in vivo.
-
Use of curcumin and its nanopreparations in the treatment of inflammatory bowel disease. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Zi-Wen Meng, Bing Chang, Li-Xuan Sang
Inflammatory bowel disease (IBD) is a nonspecific inflammatory disease of the intestine that includes Crohn's disease and ulcerative colitis. Because IBD is difficult to heal and easily relapses, it could worsen patient quality of life and increase economic burdens. Curcumin (CUR) is a bioactive component derived from the rhizome of turmeric (Curcuma longa). Many basic and clinical studies have shown
-
Garg incontinence scores: New scoring system on the horizon to evaluate fecal incontinence. Will it make a difference? World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Petr Tsarkov, Inna Tulina, Parvez Sheikh, Darya D Shlyk, Pankaj Garg
The main aim of this opinion review is to comment on the recent article published by Garg et al in the World Journal of Gastroenterology 2023; 29: 4593-4603. The authors in the published article developed a new scoring system, Garg incontinence scores (GIS), for fecal incontinence (FI). FI is a chronic debilitating disease that has a severe negative impact on the quality of life of the patients. Rome
-
Cholecystokinin and cholecystokinin-A receptor: An attractive treatment strategy for biliary dyskinesia? World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Jun Chang, Yan Liu, Ting-Can Jiang, Lan Zhao, Jian-Wei Liu
Biliary dyskinesia is a relatively common gastrointestinal disease that is increasing in incidence as living standards improve. However, its underlying pathogenesis remains unclear, hindering the development of therapeutic drugs. Recently, "Expression and functional study of cholecystokinin-A receptors on the interstitial Cajal-like cells of the guinea pig common bile duct" demonstrated that cholecystokinin
-
Toward less invasive coloproctology: The future is out there. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Sameh Hany Emile, Jonathan Ragheb
Medical care has undergone remarkable improvements over the past few decades. One of the most important innovative breakthroughs in modern medicine is the advent of minimally and less invasive treatments. The trend towards employing less invasive treatment has been vividly shown in the field of gastroenterology, particularly coloproctology. Parallel to foregut interventions, colorectal surgery has
-
Relationship among Parkinson's disease, constipation, microbes, and microbiological therapy. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Xin-Yang Yuan, Yu-Sen Chen, Zhou Liu
This comprehensive review elucidates the complex interplay between gut microbiota and constipation in Parkinson's disease (PD), a prevalent non-motor symptom contributing significantly to patients' morbidity. A marked alteration in the gut microbiota, predominantly an increase in the abundance of Proteobacteria and Bacteroidetes, is observed in PD-related constipation. Conventional treatments, although
-
Effectiveness of antibiotic prophylaxis for acute esophageal variceal bleeding in patients with band ligation: A large observational study. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Chikamasa Ichita, Sayuri Shimizu, Tadahiro Goto, Uojima Haruki, Naoya Itoh, Masao Iwagami, Akiko Sasaki
Esophageal variceal bleeding is a severe complication associated with liver cirrhosis and typically necessitates endoscopic hemostasis. The current standard treatment is endoscopic variceal ligation (EVL), and Western guidelines recommend antibiotic prophylaxis following hemostasis. However, given the improvements in prognosis for variceal bleeding due to advancements in the management of bleeding
-
Why is early detection of colon cancer still not possible in 2023? World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Valeria Tonini, Manuel Zanni
Colorectal cancer (CRC) screening is a fundamental tool in the prevention and early detection of one of the most prevalent and lethal cancers. Over the years, screening, particularly in those settings where it is well organized, has succeeded in reducing the incidence of colon and rectal cancer and improving the prognosis related to them. Despite considerable advancements in screening technologies
-
SLC6A14 promotes ulcerative colitis progression by facilitating NLRP3 inflammasome-mediated pyroptosis. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-2-5 Qing Gu, Huan Xia, Yue-Qiong Song, Jun Duan, Yun Chen, You Zhang, He-Ping Chen, Li Zhang
Ulcerative colitis (UC) is an inflammatory condition with frequent relapse and recurrence. Evidence suggests the involvement of SLC6A14 in UC pathogenesis, but the central regulator remains unknown.
-
Mechanistic research: Selenium regulates virulence factors, reducing adhesion ability and inflammatory damage of Helicobacter pylori. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-1-31 Chun Qin, Gan-Rong Huang, Ai-Xing Guan, Wen-Ting Zhou, Hao Chen, Pei-Pei Luo, Xian-Ke Luo, Yan-Qiang Huang, Zan-Song Huang
The pathogenicity of Helicobacter pylori is dependent on factors including the environment and the host. Although selenium is closely related to pathogenicity as an environmental factor, the specific correlation between them remains unclear.
-
May ChatGPT be a tool producing medical information for common inflammatory bowel disease patients' questions? An evidence-controlled analysis. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-1-31 Antonietta Gerarda Gravina, Raffaele Pellegrino, Marina Cipullo, Giovanna Palladino, Giuseppe Imperio, Andrea Ventura, Salvatore Auletta, Paola Ciamarra, Alessandro Federico
Artificial intelligence is increasingly entering everyday healthcare. Large language model (LLM) systems such as Chat Generative Pre-trained Transformer (ChatGPT) have become potentially accessible to everyone, including patients with inflammatory bowel diseases (IBD). However, significant ethical issues and pitfalls exist in innovative LLM tools. The hype generated by such systems may lead to unweighted
-
Editor-in-Chief articles of choice and comments at the year-end of 2023. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-1-31 Andrzej S Tarnawski
As the Editor-in-Chief of World Journal of Gastroenterology, every week prior to a new issue's online publication, I perform a careful review of all encompassed articles, including the title, clinical and/or research importance, originality, novelty, and ratings by the peer reviewers. Based on this review, I select the papers of choice and suggest pertinent changes (e.g., in the title) to the Company
-
Complementary comments on diagnosis, severity and prognosis prediction of acute pancreatitis. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-1-31 Muhsin Ozgun Ozturk, Sonay Aydin
The radiological differential diagnosis of acute pancreatitis includes diffuse pancreatic lymphoma, diffuse autoimmune pancreatitis and groove located mass lesions that may mimic groove pancreatitis. Dual energy computed tomography and diffusion weighted magnetic resonance imaging are useful in the early diagnosis of acute pancreatitis, and dual energy computed tomography is also useful in severity
-
Use of endoscopic ultrasound-guided gallbladder drainage as a rescue approach in cases of unsuccessful biliary drainage. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-1-31 Alessandro Fugazza, Kareem Khalaf, Katarzyna M Pawlak, Marco Spadaccini, Matteo Colombo, Marta Andreozzi, Marco Giacchetto, Silvia Carrara, Chiara Ferrari, Cecilia Binda, Benedetto Mangiavillano, Andrea Anderloni, Alessandro Repici
This narrative review provides an overview of the utilization of endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) as a salvage approach in cases of unsuccessful conventional management. EUS-GBD is a minimally invasive and effective technique for drainage in patients with acute cholecystitis with high risk of surgery. The procedure has demonstrated impressive technical and clinical success
-
Crohn's disease as the intestinal manifestation of pan-lymphatic dysfunction: An exploratory proposal based on basic and clinical data. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-1-31 Yu-Wei Zhou, Yue Ren, Miao-Miao Lu, Ling-Ling Xu, Wei-Xin Cheng, Meng-Meng Zhang, Lin-Ping Ding, Dong Chen, Jian-Guo Gao, Juan Du, Ci-Liang Jin, Chun-Xiao Chen, Yun-Fei Li, Tao Cheng, Peng-Lei Jiang, Yi-Da Yang, Peng-Xu Qian, Peng-Fei Xu, Xi Jin
Crohn's disease (CD) is caused by immune, environmental, and genetic factors. It can involve the entire gastrointestinal tract, and although its prevalence is rapidly increasing its etiology remains unclear. Emerging biological and small-molecule drugs have advanced the treatment of CD; however, a considerable proportion of patients are non-responsive to all known drugs. To achieve a breakthrough in
-
2023: A year of accomplishments for the 13 Science Citation Index Expanded- and Emerging Sources Citation Index-indexed Baishideng journals. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-1-31 Jin-Lei Wang, Jia-Ping Yan, Jia-Ru Fan, Xiang Li, Xu Guo, Jia-Wei Li, Yun-Xiaojian Wu, Jing-Jie Wang, Yu-Lu Chen, Li Li, Cong Lin, Xin-Liang Qu, Ji-Hong Liu, Yan-Liang Zhang, Ying-Yi Yuan, Hua-Ge Yu, Yu-Xi Chen, Yi-Xuan Cai, Xiang-Di Zhang, Si Zhao, Zi-Hang Xu, Li Ma, Na Ma, Diao-Mei Guo, Lian-Sheng Ma
In 2023, Baishideng Publishing Group (Baishideng) routinely published 47 open-access journals, including 46 English-language journals and 1 Chinese-language journal. Our successes were accomplished through the collective dedicated efforts of Baishideng staffs, Editorial Board Members, and Peer Reviewers. Among these 47 Baishideng journals, 7 are included in the Science Citation Index Expanded (SCIE)
-
Machine learning identifies the risk of complications after laparoscopic radical gastrectomy for gastric cancer. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-1-31 Qing-Qi Hong, Su Yan, Yong-Liang Zhao, Lin Fan, Li Yang, Wen-Bin Zhang, Hao Liu, He-Xin Lin, Jian Zhang, Zhi-Jian Ye, Xian Shen, Li-Sheng Cai, Guo-Wei Zhang, Jia-Ming Zhu, Gang Ji, Jin-Ping Chen, Wei Wang, Zheng-Rong Li, Jing-Tao Zhu, Guo-Xin Li, Jun You
Laparoscopic radical gastrectomy is widely used, and perioperative complications have become a highly concerned issue.
-
Effect of magnetic resonance imaging in liver metastases. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-1-31 Xing-Liang Huang, Xiao-Dong Wang, Zhao-Miao Gong, Yan-Feng Zheng, Jing-Xin Mao
This letter to the editor is a commentary on a study titled "Liver metastases: The role of magnetic resonance imaging." Exploring a noninvasive imaging evaluation system for the biological behavior of hepatocellular carcinoma (HCC) is the key to achieving precise diagnosis and treatment and improving prognosis. This review summarizes the role of magnetic resonance imaging in the detection and evaluation
-
Treat to target in Crohn's disease: A practical guide for clinicians. World J. Gastroenterol. (IF 4.3) Pub Date : 2024-1-31 Ashish R Srinivasan
A treat-to-target (T2T) approach applies the principles of early intervention and tight disease control to optimise long-term outcomes in Crohn's disease. The Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE)-II guidelines specify short, intermediate, and long-term treatment goals, documenting specific treatment targets to be achieved at each of these timepoints. Scheduled appraisal
-
Paying attention to the value of thrombelastography and the impact of postreperfusion syndrome on outcomes of liver transplantation. World J. Gastroenterol. (IF 4.3) Pub Date : 2023-12-22 Yu-Li Wu, Lu Che, Yi-Qi Weng
Only limited information is available about the connection between massive blood transfusion and postoperative survival rates in pediatric liver transplantation. The aim of Gordon's study was to examine the potential impact of perioperative transfusion on postoperative complications and death in young children receiving pediatric living-donor liver transplantation (PLDLT). The authors concluded that
-
Frailty in end-stage liver disease: Understanding pathophysiology, tools for assessment, and strategies for management. World J. Gastroenterol. (IF 4.3) Pub Date : 2023-12-22 Mazen Elsheikh, Ahmed El Sabagh, Islam B Mohamed, Megha Bhongade, Manal M Hassan, Prasun Kumar Jalal
Frailty and sarcopenia are frequently observed in patients with end-stage liver disease. Frailty is a complex condition that arises from deteriorations across various physiological systems, including the musculoskeletal, cardiovascular, and immune systems, resulting in a reduced ability of the body to withstand stressors. This condition is associated with declined resilience and increased vulnerability
-
Surgical complications after pancreatic transplantation: A computed tomography imaging pictorial review. World J. Gastroenterol. (IF 4.3) Pub Date : 2023-12-22 Carlo D'Alessandro, Matteo Todisco, Caterina Di Bella, Filippo Crimì, Lucrezia Furian, Emilio Quaia, Federica Vernuccio
Pancreatic transplantation is considered by the American Diabetes Association and the European Association for the Study of Diabetes an acceptable surgical procedure in patients with type 1 diabetes also undergoing kidney transplantation in pre-final or end-stage renal disease if no contraindications are present. Pancreatic transplantation, however, is a complex surgical procedure and may lead to a