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Association of low serum 25-Hydroxy vitamin D [25(OH) d] with hepatic encephalopathy in patients with decompensated liver cirrhosis Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-03-08 Abdul Mumit Sarkar, Abdullah Al Mukit, Tanzilul Bari, Rofiqul Islam, Shafiqul Islam, Khalequzzaman Sarker, Manzurul Chowdhury, Mohd. Harun Or Rashid, Abdul Alim
The mechanism of hepatic encephalopathy is complex and has not been conclusively established. Recent studies support lower serum 25-Hydroxy Vitamin D [25(OH) D] levels in patients with hepatic encephalopathy. This study aimed to evaluate the association between serum 25(OH) D and hepatic encephalopathy in patients with decompensated cirrhosis of liver. A total of 70 cirrhosis patients (35 cases of
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The impact of EndoCuff-assisted colonoscopy on the polyp detection rate: A cross-over randomized back-to-back study Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-02-27 Mohammed Sherif Naguib, Ahmed Khairy, Hany Shehab, Hazem Abosheaishaa, Abdel Meguid Kassem
Colorectal cancer (CRC) is one of the most common cancers worldwide, and most CRCs develop from polyps with malignant potential. We aimed to study the difference in polyp detection rate between EndoCuff-assisted colonoscopies (EAC) and standard colonoscopy (SC). This study was conducted at Cairo University Hospitals on patients referred for screening or diagnostic colonoscopy from July 2018 to August
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Differences in circulating lymphocyte subpopulations among patients with inflammatory polyps, colorectal adenomas and colorectal cancer Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-02-26 Jialai Zheng, Haiyong Jin, Yongtao Tu
Colorectal cancer (CRC) may develop from focal changes within benign or precancerous polyps. The immune system’s failure to detect and eradicate tumor cells due to immune surveillance evasion, allows cancer to develop and spread. This study aims to analyze the differences in circulating lymphocyte subpopulations in patients with colorectal inflammatory polyps, colorectal adenomas and CRC. We retrospectively
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Multidrug resistance Gene-1 polymorphisms (C3435T and G2677T) and the risk of inflammatory bowel disease in Egyptian patients Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-02-26 Raghda Marzaban, Rania Mohamed Samy, Mona Ahmed Kassem, Mira Atef
The multidrug resistance 1 (MDR1) gene is a gene involved in the pathogenesis of inflammatory bowel disease (IBD).The aim of the study is to investigate the association of MDR-1 gene polymorphisms (C2345T and G2677T) and IBD incidence in Egyptian patients, and its relation with disease severity. This is a case-control study where genotyping of MDR-1 gene C3435T and G2677T single nucleotide polymorphisms
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Sonographic features of Lemmel’s syndrome: Differential diagnosis from stones in the lower portion of the common bile duct Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-02-24 Jinxiu Ju, Yating Su, Qingjing Zeng, Jiayi Liang, Xiaodan Zhang, Jie Ren, Lili Wu, Rongqin Zheng
Periampullary diverticula (PAD), a location-specific type of duodenal diverticula, can cause serious complications. PAD is difficult to differentially diagnose, mainly due to its nonspecific symptoms. This study aimed to identify sonographic features of PAD and to evaluate their value in the differential diagnosis of PAD from stones in the lower common bile duct (CBD). A total of 30 patients with PAD
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Effect of lidocaine on postoperative analgesia of endoscopic rubber band ligation combined with injection sclerotherapy for treatment of internal hemorrhoids: A retrospective study (with video) Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-02-24 Wen Xu, Guili Xia, Ling Dong, Ying Zhu
Endoscopic minimally invasive treatment of internal hemorrhoids may cause postoperative pain. The aim of the study is to investigate the analgesic effect of lidocaine plus lauromacrogol on postoperative pain caused by endoscopic rubber band ligation (ERBL) combined with injection sclerotherapy (IS) for internal hemorrhoids treatment. Clinical data of grade Ⅲ internal hemorrhoids patients who underwent
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Efficacy of L-ornithine L-aspartate for minimal hepatic encephalopathy in patients with cirrhosis: A meta-analysis of randomized controlled trials Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-02-24 Qiufeng He, Chuangjie Mao, Zhili Chen, Yilan Zeng, Yang Deng, Rong Hu
Minimal hepatic encephalopathy (MHE) is an early stage of hepatic encephalopathy (HE) and is highly prevalent. The efficacy of L-ornithine L-aspartate (LOLA) for the treatment of HE is well known but its role in MHE remains uncertain. The objectives of the current study were to evaluate the efficacy of LOLA for the treatment of MHE in patients with cirrhosis. The Cochrane Library, PubMed, EMBASE, Web
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The role of IL-19, IL-24, IL-21 and IL-33 in intestinal mucosa of inflammatory bowel disease: A narrative review Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-02-23 Alexandros Toskas, Stefanos Milias, Theodora Papamitsou, Soultana Meditskou, Nikolaos Kamperidis, Antonia Sioga
Interleukins are potential therapeutic targets that can alter the prognosis and progression of inflammatory bowel disease (IBD). The roles of IL-6, IL-10, IL-17, and IL-23 have been extensively studied, setting the stage for the development of novel treatments for patients with IBD. Other cytokines have been less extensively studied. Members of the IL-20 family, mainly IL-19 and IL-24, are involved
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Acyl ghrelin, desacyl ghrelin and their ratio affect hepatic steatosis via PPARγ signaling pathway Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-02-21 Emine Elibol, Yasemin Akdevelioğlu, Canan Yılmaz, Belkıs Narlı, Serkan Şen, Gülnur Take Kaplanoğlu, Cemile Merve Seymen
Ghrelin is an appetite hormone-containing 28-amino acid and has 4 different forms in the body. Ghrelin forms have different physiological functions in the body. This study aims to analyze the effect of acyl and desacyl ghrelin hormone on hepatic steatosis and biochemical findings in 36 male Wistar rats. Rats were split into 6 equal groups, consisting of control, acyl ghrelin, desacyl ghrelin, acyl/desacyl
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Risk of tuberculosis with anti-TNF therapy in Indian patients with inflammatory bowel disease despite negative screening Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-02-21 Suprabhat Giri, Sukanya Bhrugumalla, Akash Shukla, Sagar Gangadhar, Srujan Reddy, Sumaswi Angadi, Leela Shinde, Aditya Kale
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Risk factors of liver abscess and biloma formation after drug-eluting bead transarterial chemoembolization for unresectable intrahepatic cholangiocarcinoma Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-02-21 Longhao Bian, Jianjun Yang, Zhaomin Song
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Effects of HMGA2 on the biological characteristics and stemness acquisition of gastric cancer cells Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-02-19 Dequan Kong, Lang Zha, Yaben Yao, Zhenyu Zhang, Jun Gao, Rui Zhang, Lei Chen, Ziwei Wang
The high mobility group A2 (HMGA2), a nonhistone nuclear binding protein, modulates transcription by altering the chromatin architecture of the target gene DNA in its specific AT-hooks region. HMGA2 overexpression has been observed in embryonic tissue and many malignant neoplasms. This study sought to verify whether HMGA2 plays a role in the biological functions of gastric cancer cells, such as cell
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Diabetic patients with chronic hepatitis C virus response compared to non diabetics when treated with directly acting antiviral therapy Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-02-19 Raghda N. Marzaban, Hesham I. AlMekhzangy, Wafaa ElAkel, Tamer M ElBaz, Yehia M. ElShazly, Kadry ElSaeed, Mahmoud Anees, Mohamed Said, Magdy A. ElSerafy, Gamal G. Esmat, Wahid H. Doss
Hepatitis C virus (HCV) impairs glucose homoestasis, thus influences its clinical picture and prognosis. Adult patients with CHC were divided into 2 groups; Diabetic patients, and Non diabetic patients serving as control group. All patients were subjected to thorough clinical evaluation, basic biochemical laboratory tests including fasting blood glucose/glycosylated haemoglobin (HbA1C), and virologic
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Dietary composition and its association with metabolic dysfunction-associated fatty liver disease among Chinese adults: A cross-sectional study Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-02-19 Zuohu Niu, Jing Liu, Hongye Peng, Xuan Wu, Xinzhuo Zheng, Shukun Yao, Chunjun Xu
Metabolic dysfunction-associated fatty liver disease (MAFLD) has become the most common cause of chronic liver disease worldwide. Diet plays a critical role in the prevention and treatment of MAFLD. Our hypothesis was that the intake of some macronutrients, vitamins, or mineral elements is associated with MAFLD. Patients with MAFLD can be diagnosed based on the evidence of hepatic steatosis and if
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Effect of medium chain triglycerides enriched formula on growth of biliary atresia patients after Kasai portoenterostomy Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-02-19 Nehal El-Koofy, Eman Mahmoud, Fatma El Mougy, Engy Nasr, Sawsan Okasha, Hanaa El-Karaksy, Ghada Anwar, Mortada H. El-Shabrawi, Nora E. Badawi, Noha Arafa
Biliary atresia (BA) is the most common cause of neonatal cholestasis, negatively affecting nutritional status, growth, and development. It is the most frequent paediatric indication for liver transplantation. The Kasai portoenterostomy (KPE) operation is an effective procedure with favourable outcomes when performed before two months of age. The present study aimed to assess the nutritional status
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Mucormycosis presenting as intestinal perforation: A pathologist perspective Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-02-19 Pallavi Saraf, Jyotsna Naresh Bharti
Mucormycosis is a life-threatening fungal infection mostly involving the ocular region, sinuses and brain. It is mostly seen in the immunocompromised host. Gastrointestinal (GI) mucormycosis is rare and mostly present as hematemesis, abdominal pain and melena. Here, we present a case of intestinal mucormycosis who presented as cecal perforation. Surgical resection was done, and the diagnosis was made
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Coronavirus disease 19 (Covid-19): A comparative study of pattern of liver injury in adult patients in different waves of Covid-19 infection Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-02-19 Zeinab Abdellatif, Hanan Abdel-Haleem, Rasha Ahmed Abdalaziz, Ahmed Ramadan, Aya Mohamed Al-sharif, Reem Ibrahim Mohamed El-Korashy, Youssef Mohamed Amin Soliman, Sabah Ahmed Hussein, Manal Mohamed Kamal, Mona Mohsen Abdulsalam Abdullatif, Mohammed Mustafa AbdelRazik, Noha Mohamed Tarek Eldessouky, Mira Atef
Liver dysfunction is a common manifestation of the COVID-19 infection. We aimed to study transaminase abnormalities through different waves of COVID-19 and their relations to disease severity or mortality. A retrospective study included 521 Egyptian patients diagnosed with COVID-19. Data was retrieved from the medical records of patients who were admitted from April 2020 to October 2021 in Kasr Al-Ainy
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A risk model for parenteral nutrition-associated liver disease in patients with severe acute pancreatitis Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-02-19 Zheng Chang, Hao Zhang
The aim of this study is to explore the risk factors for parenteral nutrition-associated liver disease (PNALD) in patients with severe acute pancreatitis by establishing a verification risk model. A total of 176 patients with severe acute pancreatitis from January 2019 to August 2021, were assigned into the observation group (n = 88) and control group (n = 88) based on the diagnostic results of PNALD
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TGF-β1 inhibitor P144 protects against benign restenosis after esophageal stenting through TGF-β1/Smads signaling pathway inhibition Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-02-18 Jun-Zheng Wu, Chun Zhou, Sheng Liu, Jin-Xing Zhang, Wei Yang, Hai-Bin Shi, Wei-Zhong Zhou
Esophageal restenosis is a serious complication after esophageal stent placement, which influences the clinical prognosis of stent implantation and the patient's quality of life. TGF-β1/Smads signaling pathway plays an important role in the development of the eosinophilic esophagitis and scar repair after skin trauma. However, the role of TGF-β1/Smads in the development of esophageal restenosis after
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Brunner’s gland hamartomas: Not always benign Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-01-30 Manar Shmais, Ahmad Mousawi, Fadi Mourad, Ala I. Sharara
Brunner’s gland hamartoma (BGH) is a rare, benign tumor of the duodenum. It is mostly asymptomatic and usually found incidentally on routine esophagogastroduodenoscopy (EGD). However, some BGHs present with major complications including anemia, bleeding, obstruction, or dysplasia, requiring management and resection of these lesions. Herein, we present two cases of large BGHs of the duodenum, one presenting
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Liver imaging reporting and data system diagnostic performance in hepatocellular carcinoma when modifying the definition of “washout” on gadoxetic acid-enhanced magnetic resonance imaging Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-01-20 Weijuan Hu, Rong Lyu, Di Wang, Zhongsong Gao, Cheng Sun, Kefeng Jia
Background and study aims The sensitivity of the Liver Imaging Reporting and Data System (LI-RADS) in the diagnosis of hepatocellular carcinoma (HCC) on gadoxetic acid-enhanced magnetic resonance imaging (EOB-MRI) was suboptimal. This study evaluated the LI-RADS diagnostic performance in HCC when modifying the definition of washout using the transition phase (TP) or hepatobiliary phase (HBP) hypointensity
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Enhanced non-alcoholic fatty liver detection: Computed tomography scan image analysis and noise reduction with morphological dilation Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-01-19 Kishan Dev Pithani, Radhika Vadhi
Non-alcoholic fatty liver disease (NAFLD) is characterized by accumulation of fat in the liver cells caused by means other than alcohol consumption. It is one of the most common chronic liver diseases worldwide and can lead to severe conditions, such as cirrhosis and liver cancer. NAFLD is often associated with other metabolic disorders, such as obesity and diabetes, and is closely related to lifestyle
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Primary hydatid cyst of the spleen: A rare pathology case report and literature revue Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-01-18 Elias Makhoul, Marc Harb, Selim Makhoul
Hydatidosis is an endemic disease in certain areas in the world particularly in the Mediterranean, the Middle East, and South America, caused by a cestode known as Echinococcus granulosus. Humans are the accidental intermediate hosts. The liver and the lungs are the most commonly involved organ. If the parasite passes through the pulmonary capillary bed, the hydatid cyst may develop at any site in
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Endoscopic retrieval of migrated Foley catheter: A clinical case series Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-01-15 Karan Muzumdar, Ankita Singh, Sridhar Sundaram
Use of Foley catheter in patients with ileostomy, for the decompression of large bowel distal to stoma or for the administration of large bowel enema through colostomy, either to treat constipation or for bowel preparation prior to colonoscopy, is a common practice. Accidental migration of catheter during bowel irrigation through stoma can take place if it is not secured externally to the skin. We
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ChatGPT's ability to comprehend and answer cirrhosis related questions: Comment Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-01-16 Hinpetch Daungsupawong, Viroj Wiwanitkit
Abstract not available
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GPC2 as a diagnostic and prognostic marker regulated progression of colorectal cancer Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-01-13 Rugang Wang, Xuan Lin
Background and study aims Glypican 2 (GPC2) is a member of the glypican gene family and is expressed in multiple kinds of cancer. However, the function and mechanism of GPC2 in colorectal cancer remains unclear. In this study, we aimed to identify the role of GPC2 on tumor cell proliferation and survival in colorectal cancer. Patients and methods Ten pairs of colon cancer and matched normal colon tissues
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Application of artificial intelligence in gastrointestinal endoscopy Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-01-15 Fujia Guo, Hua Meng
Endoscopy is an important method for diagnosing gastrointestinal (GI) diseases. In this study, we provide an overview of the advances in artificial intelligence (AI) technology in the field of GI endoscopy over recent years, including esophagus, stomach, large intestine, and capsule endoscopy (small intestine). AI-assisted endoscopy shows high accuracy, sensitivity, and specificity in the detection
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Rare liver diseases in Egypt: Clinical and epidemiological characterization Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-01-15 Walaa Abdelhamed, Mohamed El-Kassas
Illnesses that afflict a tiny number of individuals are referred to as rare diseases (RDs), sometimes called orphan diseases. The local healthcare systems are constantly under financial, psychological, and medical strain due to low incidence rates, unusual presentations, flawed diagnostic standards, and a lack of treatment alternatives for these RDs. The effective management of the once widely spread
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Correlation of chronic atrophic gastritis with gastric-specific circulating biomarkers Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-01-13 Haitao Yu, Haibing Wang, Haigang Pang, Qingju Sun, Ying Lu, Qunying Wang, Wenzhu Dong
Background and study aims It has been suggested that the combined detection of multiple serum biomarkers can effectively screen out the high-risk population of chronic atrophic gastritis in the general population. Therefore, it is necessary to establish an effective predictive model of chronic atrophic gastritis. Patients and methods Serum biopsies were assessed using five stomach-specific circulating
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Artificial Intelligence in endoscopy: A future poll Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-01-13 Omar Elshaarawy, Mohamed Alboraie, Mohamed El-Kassas
Artificial Intelligence [AI] has been a trendy topic in recent years, with many developed medical applications. In gastrointestinal endoscopy, AI systems include computer-assisted detection [CADe] for lesion detection as bleedings and polyps and computer-assisted diagnosis [CADx] for optical biopsy and lesion characterization. The technology behind these systems is based on a computer algorithm that
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miR-129-2-3p inhibits colon cancer cell proliferation by down-regulating the expression of BZW1 Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-01-13 Liang Tao, Peng Song, Lihua Shao, Hengfei Gao, Kangkang Ji, Yan Ren, Feng Wang, Meng Wang
Background and study aims MicroRNA (miRNA) is involved in diverse biological and physiological processes of tumors. Dysregulation of miRNA will induce a series of human diseases. miR-129-2-3p has vital effects in the pathogenesis of various tumors. However, the regulatory function of miR-129-2-3p in colon cancer remains to be clarified. This study investigated the role of miR-129-2-3p targeting BZW1
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C-X-C motif chemokine receptor 4 inhibition promotes the effect of plantamajoside in hepatocellular carcinoma Arab J. Gastroenterol. (IF 1.4) Pub Date : 2024-01-13 Jiajia Sun, Wei Liu, Hao Fu, Yibei Li, Jiaqi Huang, Yuxi Wang, Lei Zhu
Background and study aim Hepatocellular carcinoma (HCC) is the fifth leading cause of cancer-related mortality worldwide, and, more than half of these cases are diagnosed in China. However, effective treatment for HCC is still limited. Material and methods C-X-C motif chemokine receptor 4 (CXCR4) was first activated and inhibited in HepG2 cells using a pharmacological method. HepG2 cell proliferation
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Urgent colonoscopy is not necessary in case of colonic diverticular bleeding without extravasation on contrast-enhanced computed tomography Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-11-21 Tomoya Sugiyama, Yuki Kojima, Yoshikazu Hirata, Masahide Ebi, Takashi Yoshimine, Kazunori Adachi, Yoshiharu Yamaguchi, Shinya Izawa, Yasutaka Hijikata, Yasushi Funaki, Naotaka Ogasawara, Makoto Sasaki, Wataru Ohashi, Satoshi Sobue, Kunio Kasugai
Background and aims Acute lower gastrointestinal bleeding (ALGIB) increase with age and the administration of antiplatelet drugs. Colonic diverticular bleeding (CDB) is the most common cause of ALGIB, and endoscopic hemostasis is an effective treatment for massive CDB. But in patients without extravasation on contrast-enhanced computed tomography (CECT), the efficacy of urgent colonoscopy (UCS) is
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Intestinal fungal profile in healthy Saudi children Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-11-22 Mohammad El Mouzan, Abdulrahman Al Hussaini, Ahmed Al Sarkhy, Asaad Assiri
Background and study aim Fungi have a well-established role in medicine. Herein, we describe the fungal profile and abundance in the gut of healthy Saudi children. Patients and methods Fecal samples from a random sample of 20 school-age Saudi children were collected, stored at −80 °C, and dispatched to the laboratory in the USA where fungal DNAs were isolated and shotgun metagenomic sequencing was
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Acute abdominal perforation as a clinical presentation of coeliac disease Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-11-21 Janaína Luz Narciso-Schiavon, Karoline Kuhnen Fonseca, Jandir Santos Silva, Sarah Sayuri Tiemi Rodrigues, Lee I-Ching, Arthur Conelian Gentili, Cintia Zimmermann De Meireles, Janaina Sant'Ana Fonseca, Luiz Augusto Lacombe, Leonardo De Lucca Schiavon
Intestinal perforation is described in coeliac disease in the setting of refractoriness or Enteropathy-Associated T-cell Lymphoma (EATL). We report the case of a man with untreated coeliac disease who presented intestinal perforation and was diagnosed with EATL over one year later.
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Performance of FibroScan in grading steatosis and fibrosis in patients with nonalcoholic fatty liver disease: A meta-analysis Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-11-22 Xiaotong Xu, Jinglan Jin, Yuwei Liu
Objective: Biopsy remains the gold standard for the diagnosis of Non-alcoholic fatty liver disease (NAFLD). To investigate the diagnostic value of FibroScan based on biopsy and range of cut-offs for steatosis and fibrosis, we explored the grade of steatosis and fibrosis. Method: A simultaneous search was performed on cohort studies published earlier than October 8, 2020,in the PubMed, Web of Science
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Acquired factor VII deficiency in pediatric inflammatory bowel disease: Report of three cases Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-11-22 Sevim Çakar, Gülin Eren, Tuba Hilkay Karapınar, Çiğdem Ömür Ecevıt, Özlem Bekem
Bleeding disorders can exacerbate gastrointestinal bleeding in inflammatory bowel disease (IBD) at the time of diagnosis or flares. Factor VII (FVII) deficiency is a life-threatening rare congenital bleeding disorder in childhood. This study describes three adolescent patients with IBD accompanied by acquired FVII deficiency. This is the first case series of patients with IBD accompanied by FVII deficiency
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Non-alcoholic fatty liver disease and periodontal disease: A systematic review and meta-analysis of cross-sectional studies Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-11-22 Inácio Lima Silva Aguiar, Larissa Souza Santos-Lins, Rebeca Brasil-Oliveira, Helma Pinchemel Cotrim, Liliane Lins-Kusterer
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease, comprising hepatic steatosis, and non-alcoholic steatohepatitis. Periodontal disease (PD) may be a risk factor for the evolution of liver cirrhosis. This study aimed to evaluate the association between NAFLD and PD. We searched in Pubmed, Scopus, Cochrane, and Lilacs databases with descriptors (Non-alcoholic Fatty Liver Disease OR
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Could immediate second-look endoscopy reduce post-endoscopic submucosal dissection bleeding? Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-11-22 Dong Jun Oh, Hyoung Jung Na, Ji Hyung Nam, Yun Jeong Lim, Jae Hak Kim
Background and study aim Gastric endoscopic submucosal dissection (ESD) is a curative treatment for gastric neoplasm. A scheduled second-look endoscopy could be performed to prevent delayed post-ESD bleeding. However, no studies on the efficacy of second-look endoscopy for the prevention of early delayed post-ESD bleeding have been conducted. So, the aim of this study was to be the first to investigate
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Large spontaneous HBV DNA fluctuations and potential usefulness of a single-point measurement of combined HBV DNA and quantitative HBsAg for the exclusion of HBeAg-negative chronic hepatitis B: A prospective Tunisian cohort study Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-11-21 Amel Chtourou, Saba Gargouri, Emna Elleuch, Lamia Feki, Fahmi Smaoui, Awatef Taktak, Khouloud Mnif, Mondher Kassis, Adnene Hammami, Mounir Ben Jemaa, Hela Karray
Background and study aim During the natural course of HBeAg-negative chronic hepatitis B (CHB), fluctuations in hepatitis B virus (HBV) DNA and alanine aminotransferase (ALT) levels are often observed, making the classification of patients difficult. We aimed to describe spontaneous short-term HBV DNA level fluctuations and to assess the usefulness of qHBsAg in Tunisian patients with HBeAg-negative
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Liver fibrosis in pars cohort study: A large-scale study on the prevalence and correlated factors Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-11-21 Amin Nakhostin-Ansari, Seyed Hossein Hosseini-Asl, Fatemeh Aliasgharpour, Mohammad Ahmadi, Abdollah Gandomkar, Fatemeh Malekzadeh, Hossein Poustchi, Mohammad Reza Fattahi, Amir Anushiravani, Reza Malekzadeh
Backgrounds and study aims The fibrosis-4 (FIB-4) is a non-invasive scoring system for estimating liver fibrosis severity as a biomarker of chronic liver disease. We aimed to estimate the prevalence and severity of chronic liver disease at the community level using FIB-4. Patients and methods This cross-sectional study was conducted using the Pars Cohort database collected in Valashar, Fars province
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Serum Cys C predicts acute kidney injury in patients with acute pancreatitis: A retrospective study Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-11-21 Ningzhi Wang, Fei Han, Jiajia Pan, Guanghuai Yao, Yao Wang, Songxin Xu, Weiming Xiao, Yanbing Ding, Chunfang Xu
Background and study aims We investigated the value of the serum cystatin C level as a potential predictor of acute kidney injury (AKI) in patients with acute pancreatitis (AP). Patients and Methods We retrospectively examined patients diagnosed with AP between January 2013 and December 2018. Patients were categorized into two groups based on their serum cystatin C levels after admission: the normal
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Improved effects of the b-value for 2000 sec/mm2 DWI on an accurate qualitative and quantitative assessment of rectal cancer Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-11-20 Zhihua Lu, Kaijian Xia, Heng Jiang, Xiaoyan Weng, Mei Wu
Background and study objectives A higher b-value Diffusion-weighted imaging (DWI) would improve the contrast between cancerous and noncancerous tissue. Apparent diffusion coefficient (ADC)-histogram analysis is a method that can provide statistical data and quantitative information on tumor heterogeneity. This study aimed to compare two high b-values (1000 and 2000 sec/mm2) DWI in tumor detection and
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Comparison of the efficacy of diltiazem versus fluoxetine in the treatment of distal esophageal spasm: A randomized-controlled-trial Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-09-15 Mojgan Forootan, Mohsen Rajabnia, Ahmad Ghorbanpoor Rassekh, Saeed Abdi, Mobin Fathi, Mohamad Amin Pourhoseingholi, Pardis Ketabi Moghadam
Background and study aim Distal esophageal spasm is an uncommon esophageal motility disorder presenting with non-cardiac chest pain and dysphagia. The main goal of therapy is symptom relief with pharmacologic, endoscopic, and surgical therapies. Pharmacologic treatment is less invasive and is the preferred method of choice. The purpose of this study was to compare the effectiveness of diltiazem versus
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Efficacy of endoscopic ultrasound-guided pelvic abscess drainage for pelvic abscesses: A case series study Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-09-09 Koichi Soga, Akinobu Sai, Hiroaki Kitae
Background and study aim This is a retrospective study to evaluate the safety and efficacy of endoscopic ultrasound-guided pelvic abscess drainage (EUS-PAD) in a single hospital setting. Patients and methods The referral criteria for EUS-PAD included patients with a pelvic abscess (PA) that was amenable for the procedure. A total of 14 patients with PA treated with EUS-PAD were included in this study
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Balloon-occluded retrograde transvenous obliteration and simultaneous endoscopic cyanoacrylate injection for treating gastric varices draining through gastrorenal shunts Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-09-09 Jindong Chu, Zheng Lu, Chunsheng Chi, Wenhui Zhang, Qian Bi, Xuemei Ma, Lijun Shen, Qin Wu, Yanling Wang, Jingjing Han, Xiaoli Yu, Bo Jin
Background and study aims Balloon-occluded retrograde transvenous obliteration-assisted endoscopic cyanoacrylate injection (E-BRTO) temporarily treats gastric fundic varices draining through gastrorenal shunts (GRS) occluding the GRS with a balloon, then endoscopically injecting cyanoacrylate. We retrospectively examined the safety, feasibility, and efficacy of E-BRTO. Patients and Methods We enrolled
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AC125611.3 promotes the progression of colon cancer by recruiting DKC1 to stabilize CTNNB1 Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-09-07 Hanqing Tang, Yuyu Dou, Yiliang Meng, Qinglan Lu, Lingling Liang
Background and study aims Previous studies have suggested that lncRNAs impact cancer progression. The lncRNA AC125611.3 (also referred to as RP11-161H23.5) is highly expressed in colon cancer but rarely studied; understanding its regulation may provide novel insights on treating colon cancer. Materials and methods qRT-PCR was performed to quantify RNAs. CCK-8 and EdU assays were performed to assess
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Corrigendum to “Hypersplenism and thrombocytopenia after exposure to ustekinumab in a patient with Crohn’s disease” [Arab J. Gastroenterol. 23 (2022) 288–289] Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-09-06 Mansour A. Altuwaijri, Maha J. Aljasser
Abstract not available
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Ileal perforation due to migrated biliary stent: A case report Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-09-04 Lujain AlZoubi, Basem Badwan, Ahmad Fayyad
Ileal perforation caused by the migration of a biliary stent is a rare complication that can occur during endoscopic stent placement for benign or malignant biliary tract diseases. The current study reports the case of a 45-year-old woman with a history of Endoscopic retrograde cholangiopancreatography (ERCP) in which a migrated biliary stent resulted in an ileal perforation.
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ChatGPT’s ability to comprehend and answer cirrhosis related questions in Arabic Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-09-04 Jamil S. Samaan, Yee Hui Yeo, Wee Han Ng, Peng-Sheng Ting, Hirsh Trivedi, Aarshi Vipani, Ju Dong Yang, Omer Liran, Brennan Spiegel, Alexander Kuo, Walid S. Ayoub
Background and study aims Cirrhosis is a chronic progressive disease which requires complex care. Its incidence is rising in the Arab countries making it the 7th leading cause of death in the Arab League in 2010. ChatGPT is a large language model with a growing body of literature demonstrating its ability to answer clinical questions. We examined ChatGPT’s accuracy in responding to cirrhosis related
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Preloading guidewire method: EUS-guided hepaticogastrostomy Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-07-31 Hirotsugu Maruyama, Yuki Ishikawa-Kakiya, Kojiro Tanoue, Akira Higashimori, Yasuhiro Fujiwara
Abstract not available
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Development of a scoring system for predicting the severity of ulcerative colitis Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-07-31 Junxiang Zeng, Xiupan Gao, Wensong Ge, Manxiu Huai, Zhigang Yang, Ting Luo, Limei Gao, Xiujun Pan
Background and study aims Monitoring disease activity in ulcerative colitis (UC) is critical in preventing long-term complications. This study aims to develop a scoring system using non-invasive indicators to predict endoscopic activities for ulcerative colitis (UC) patients. Patients and methods All enrolled patients with UC admitted to Shanghai Xinhua Hospital between June 2017 and January 2021 were
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Establishment of a nomogram for predicting functional constipation among children in China: Using the Rome IV criteria Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-07-31 Qilian Zhou, Yuxia Tang, Liping Yuan, Lingling Xu, Lijuan Yu, Zhuchun Yu, Qianqian Zhang
Background and study aims Childhood functional constipation (FC) is gradually becoming an emerging public health problem. This study aimed to develop a personalized nomogram for the prediction of incident FC among Chinese children, and the diagnosis of FC was based on the Rome IV criteria. Patients and methods This cross-sectional study was conducted from Nov. 2020 to Jan. 2021 among children residing
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Corrigendum to “Phylogenetic groups and antimicrobial resistance characteristics of Escherichia coli strains isolated from clinical samples in North Iran” [Arab J. Gastroenterol. 23 (2022) 102–107] Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-07-29 Maryam Haghighatpanah, Habib Zeighami, Amir Sasan Mozaffari Nejad, Nayyereh Hajipour
Abstract not available
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Risk analysis of 30-day rebleeding in acute non-variceal upper gastrointestinal bleeding Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-05-31 Xu Wang, Meiling Yang, Jianhua Xu, Yaxian Kuai, Bin Sun
Background and study aims This study aimed to compare the prognostic value of ABC, Glasgow-Blatchford, Rockall and AIMS65 scoring systems in predicting rebleeding rate within 30 days after endoscopic treatment of acute non-variceal upper gastrointestinal bleeding (ANVUGIB). Patients and methods A total of 93 patients with ANVUGIB were selected as the study subjects and they were divided into groups
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A transverse colon lipoma complicated with an adenoma is successfully and safely resected en bloc by endoscopic mucosal resection during water immersion Arab J. Gastroenterol. (IF 1.4) Pub Date : 2023-05-08 Hirotaka Oura, Daisuke Murakami, Makoto Arai
Abstract not available