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Smartphone Application Versus Standard Instruction for Colonoscopic Preparation: A Randomized Controlled Trial. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-03-15 Sunil V Patel, David Yu, Connie Taylor, Jackie McKay, Lawrence Hookey
To compare smartphone application (Colonoscopic Preparation) instructions versus paper instructions for bowel preparation for colonoscopy.
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Efficacy of Endoscopic Therapy in Symptomatic Pancreatic Divisum: A Systematic Review and Meta-analysis. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-03-11 Sheza Malik, Hamid Ullah, Priyadarshini Loganathan, Dushyant Singh Dahiya, Saurabh Chandan, Babu P Mohan, Douglas G Adler
Pancreas divisum (PD) is a congenital malformation of the pancreas and is implicated as a cause of pancreatitis. The role of endotherapy has been variable in symptomatic PD indicated by recurrent acute pancreatitis (RAP), chronic pancreatitis (CP), or chronic pancreatic-type abdominal pain (PP). The aim of this study was to analyze the pooled data to determine the success of endoscopic intervention
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A Deep Learning Application of Capsule Endoscopic Gastric Structure Recognition Based on a Transformer Model. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-03-04 Qingyuan Li, Weijie Xie, Yusi Wang, Kaiwen Qin, Mei Huang, Tianbao Liu, Zefeiyun Chen, Lu Chen, Lan Teng, Yuxin Fang, Liuhua Ye, Zhenyu Chen, Jie Zhang, Aimin Li, Wei Yang, Side Liu
Gastric structure recognition systems have become increasingly necessary for the accurate diagnosis of gastric lesions in capsule endoscopy. Deep learning, especially using transformer models, has shown great potential in the recognition of gastrointestinal (GI) images according to self-attention. This study aims to establish an identification model of capsule endoscopy gastric structures to improve
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Association Between Different Types of Physical Activity and Hepatic Steatosis and Liver Fibrosis: A Cross-Sectional Study Based on NHANES. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-03-01 Bo Sun, Ying Kang, Junming Zhou, Ying Feng, Wutao Wang, Xiaowei Wu, Xiaohua Zhang, Minli Li
Many studies have shown a link between physical activity (PA) and nonalcoholic fatty liver disease (NAFLD). However, more research is needed to investigate the relationship between different types of PA and NAFLD. This study aimed to explore the potential link between different types of PA, hepatic steatosis, and liver fibrosis.
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Hormonal Contraceptives Reduce Active Symptomatic Disease but May Increase Intestinal Inflammation in IBD. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-03-01 Casandra Dolovich, Leigh Anne Shafer, Lesley A Graff, Kathy Vagianos, Kelcie Witges, Laura E Targownik, Charles N Bernstein
Among women of reproductive age with inflammatory bowel disease (IBD), we aimed to assess the relationship of hormonal contraceptives (HCs) with IBD-related symptoms, and intestinal inflammation.
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Long-term Use of Proton Pump Inhibitors is Associated With An Increased Risk of Nonalcoholic Fatty Liver Disease. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-03-01 Hangkai Huang, Zhening Liu, Yanjun Guo, Yan Zeng, Shuxia Shen, Chengfu Xu
The adverse effects of long-term use of proton pump inhibitors (PPIs) have led to growing concern. The association between PPIs use and the risks of nonalcoholic fatty liver disease (NAFLD) remains controversial.
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A Review of IgG4-related Sclerosing Cholangitis (IgG4-SC). J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-02-23 Neil C Khoury, John W Birk
IgG4-related sclerosing cholangitis (IgG4-SC) is a unique, steroid-responsive, fibroinflammatory condition that is more commonly found in older men and is strongly associated with autoimmune pancreatitis (AIP). It may pose a diagnostic challenge at times due to closely mimicking hepatobiliary diseases such as primary sclerosing cholangitis (PSC), secondary sclerosing cholangitis (SSC), and cholangiocarcinoma
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Primary and Specialty Care Trainees' Perceptions About Proton Pump Inhibitor Use. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-02-19 Alex Al Khoury, Maryam Taheri Tanjani, Bretton Hari, Majid A Almadi, Myriam Martel, Alan N Barkun
Proton pump inhibitors (PPIs) are widely prescribed with proven efficacy in many indications, yet longstanding controversy about potential adverse events persists. We aimed to acquire knowledge about perceptions of outpatient PPI long-term prescribing (≥8 wk) among primary and specialty care trainees at 2 Canadian Universities.
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Comparation of 5 ml and 10 ml Negative Pressures with Wet-suction Techniques for EUS-FNA of Solid Lesions: A Single-center Randomized Controlled Trial. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-02-15 Yuchun Zhu, Yang Su, Peng Yang, Jiaojun Li, Tai Yu, Yi Wang, Xi Zhou, Ming Zhao, Xiaobin Sun, Jing Shan
The negative pressure selectable for the wet-suction technique remains uncertain. The aim was to investigate the quality of sampling and diagnostic accuracy with solid lesions by 5 mL and 10 mL negative pressure with wet-suction techniques.
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Distribution and Characteristics of Colonic Diverticula in Northern China. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-02-14 Fang Yang, Xueyue Sun, Kui Jiang
The prevalence of colonic diverticula is rising in eastern countries, possibly related to aging and the adoption of a western lifestyle. However, limited data exist regarding the distribution and endoscopic features of colonic diverticula in this population. This study aimed to assess the number, size, depth, and location of colonic diverticula in our study cohort.
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Colorectal Cancer Prevention: Is Chat Generative Pretrained Transformer (Chat GPT) ready to Assist Physicians in Determining Appropriate Screening and Surveillance Recommendations? J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-02-07 Lisandro Pereyra, Francisco Schlottmann, Leandro Steinberg, Juan Lasa
To determine whether a publicly available advanced language model could help determine appropriate colorectal cancer (CRC) screening and surveillance recommendations.
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Ustekinumab Drug Levels and Outcomes in Inflammatory Bowel Disease. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-02-01 Jessica Petrov, Sean Fine, Raneem Alzahrani, Gamal Mohamed, Badr Al-Bawardy
Data regarding the utility of therapeutic drug monitoring with ustekinumab (UST) are sparse. Our aim was to determine the correlation of UST levels with outcomes in a cohort of patients with inflammatory bowel disease (IBD).
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Efficacy, Feasibility, and Safety of the X-Tack Endoscopic HeliX Tacking System: A Multicenter Experience. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-01-29 Andrew Canakis, Sanad Maher Dawod, Enad Dawod, Malorie Simons, Bianca Di Cocco, Donevan Richard Westerveld, Roberto Paolo Trasolini, Tyler M Berzin, Christopher A Marshall, Ahmed Maher Abdelfattah, Neil B Marya, George B Smallfield, Matthew Kaspar, Guilherme M Campos, Wasseem Skef, Prashant Kedia, Terrence A Smith, Hiroyuki Aihara, Matthew T Moyer, Kartik Sampath, Srihari Mahadev, David L Carr-Locke
The application of endoscopic suturing has revolutionized defect closures. Conventional over-the-scope suturing necessitates removal of the scope, placement of the device, and reinsertion. A single channel, single sequence, through-the-scope suturing device has been developed to improve this process. This study aims to describe the efficacy, feasibility, and safety of a through-the-scope suturing device
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Colorectal Neoplasia in Asian Americans Undergoing First Time Asymptomatic Average-risk Screening Colonoscopies. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-01-29 Brendan Chen, Katie Hsia, Kirsten Loscalzo, Caitlin Fai, Samir Gupta, Sushrut Jangi
We identified the prevalence and subtype of colorectal neoplasia removed during index screening colonoscopies in a large Asian American population.
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The Crohn's Disease-Health Index: Development and Evaluation of a Novel Outcome Measure. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-01-26 Anika Varma, Jennifer Weinstein, Jamison Seabury, Spencer Rosero, Ellen Wagner, Christine Zizzi, Aaron Kaat, Elizabeth Luebbe, Nuran Dilek, John Heatwole, Lawrence Saubermann, Larissa Temple, Scott Rogoff, Chad Heatwole
We sought to develop and validate the Crohn's Disease-Health Index (CD-HI), a disease-specific, patient-reported outcome measure that serially measures Crohn's disease (CD) symptomatic burden in adults with CD.
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Somatization Mediates the Relationship Between Childhood Trauma and Pain Ratings in Patients with Irritable Bowel Syndrome. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-01-25 Abigail Schubach, Brian M Quigley, Jeffrey M Lackner, Gregory D Gudleski
To identify potential mechanisms by which childhood trauma may lead to the adult development of abdominal symptoms in patients with irritable bowel syndrome (IBS).
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Conventional Versus Traction Endoscopic Submucosal Dissection for Colorectal Tumors: A Meta-analysis of Randomized Controlled Trials. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-01-22 Sahib Singh, Babu P Mohan, Saurabh Chandan, Neil Sharma, Rakesh Vinayek, Sudhir Dutta, Sergey V Kantsevoy, Michelle Le, Douglas G Adler
Compared with conventional endoscopic submucosal dissection (C-ESD) for colorectal lesions, the traction method (T-ESD) allows the lesion to be stabilized with easier dissection. However, randomized controlled trials (RCTs) have reported conflicting results on the clinical outcomes of T-ESD as compared with C-ESD. We conducted a meta-analysis to compile the data.
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Ablation Therapy of the Biliary Tree: Status and Comprehensive Review. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-01-22 Marina Kim, Darshan Parekh, Michel Kahaleh
Malignant biliary obstruction is typically referred to endoscopists for palliation. A curative resection is indeed rarely an option in this condition. Photodynamic therapy and radiofrequency ablation are 2 modalities that can be offered in those patients. Many studies have demonstrated improved stent patency and survival after ablation. Photodynamic therapy is unfortunately very expensive and is associated
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Diagnostic Yield of Small Bowel Videocapsule Endoscopy in Patients with Iron Deficiency Anemia. A Systematic Review and meta-analysis. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-01-17 Roberta Elisa Rossi, Angelo Zullo, Silvia Ferretti, Giulia Migliorisi, Luigi Gatta, Vincenzo De Francesco, Alessandro Del Forno, Giacomo Marcozzi, Benedetta Masoni, Gianluca Franchellucci, Cesare Hassan, Alessandro Repici
Gastrointestinal (GI) bleeding or malabsorption represents the most frequent aetiologies of iron deficiency anemia (IDA). The cause of IDA remains undetermined in ~10% to 20% of patients undergoing upper and lower GI endoscopies. In this scenario, a small bowel examination with videocapsule endoscopy (VCE) is recommended. We performed a systematic review with meta-analysis to evaluate the diagnostic
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Risk Factors Associated with Advanced Colorectal Neoplasia in Adults Younger than Age 45. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-01-15 Jacquelyn Bolwell, Robert Butler, Carol A Burke, David Liska, Carole Macaron
Colorectal cancer (CRC) is rising in young adults between ages 20 to 49 years. CRC screening is endorsed for average-risk individuals beginning at ages 45 to 49 years. Targeting screening for individuals <45 years may be warranted if risk factors for advanced neoplasia can be identified.
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A Comparison of Functional Luminal Imaging Probe With High-resolution Manometry, Timed Barium Esophagram, and pH Impedance Testing to Evaluate Functional Luminal Imaging Probe's Diagnostic Capabilities. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-01-15 James D Miller, Brendan P Kemple, Joni K Evans, Steven B Clayton
The aims of this study are to determine the functional luminal imaging probe's (FLIP) diagnostic utility by comparing FLIP measurements with results from other esophageal evaluation standards.
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Utility of Intraprocedural Luminal Diameter and Distensibility Measurements During the Esophageal Peroral Endoscopic Myotomy Procedure. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-01-15 Chiemeziem Eke, Ian Greenberg, Bryce Bushe, Andrew Joelson, Priyanka Acharya, David Lee, Amrita Sethi, Prashant Kedia
Through evaluation of the lower esophageal sphincter immediately before and after myotomy using an endoluminal functional lumen imaging probe (EFLIP), our study aimed to determine the clinical response to peroral endoscopic myotomy (POEM) and the incidence of postprocedure reflux.
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The Role of Endoscopic Ultrasound-guided Fine-needle Aspiration of Pelvic Lesions: A Meta-analysis. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-01-15 Tong Su, Xiaohua Zhang, Ruixia Wang, Jing Wang, Hongwei Xu, Changqin Xu, Shulei Zhao
Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a potentially valuable tool for the diagnosis of pelvic lesions. The aim of this meta‑analysis was to evaluate the efficacy and feasibility of EUS-FNA in the diagnosis of pelvic lesions.
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Management of Irritable Bowel Syndrome With Diarrhea. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-01-15 Giovanni Marasco, Cesare Cremon, Maria Raffaella Barbaro, Vincenzo Stanghellini, Giovanni Barbara
Irritable bowel syndrome (IBS) with diarrhea (IBS-D) affects ~1% of the general population and is characterized by abdominal pain associated with diarrhea. IBS-D symptoms significantly impact the quality of life of patients. Major uncertainties remain regarding the optimal management of these patients. Several therapies have been investigated over the years for the treatment of IBS-D. In the initial
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Quality Indicator Development for the Approach to Ineffective Esophageal Motility: A Modified Delphi Study. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-01-15 Afrin N Kamal, Priya Kathpalia, David A Leiman, Albert J Bredenoord, John O Clarke, C Prakash Gyawali, David A Katzka, Adriana Lazarescu, John E Pandolfino, Roberto Penagini, Sabine Roman, Edoardo Savarino, Marcelo F Vela, Fouad Otaki
Develop quality indicators for ineffective esophageal motility (IEM).
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Management of Gastrointestinal Symptoms in Parkinson's Disease: A Comprehensive Review of Clinical Presentation, Workup, and Treatment. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-01-04 Trisha S Pasricha, Ingrid L Guerrero-Lopez, Braden Kuo
Gastrointestinal symptoms in Parkinson's disease (PD) are among the most prevalent and debilitating of complications and present unique diagnostic and management challenges. Patients with PD commonly experience dysphagia, nausea, bloating, and constipation related to pathologic involvement of the enteric nervous system. In turn, gastrointestinal complications may impact motor fluctuations and the efficacy
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The Efficacy and Safety of Regimens for Helicobacter pylori Eradication Treatment in China: A Systemic Review and Network Meta-Analysis. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2024-01-01 Jing Li, Huiying Shi, Fang Zhou, Li Xie, Rong Lin
With Helicobacter pylori's increasing antibiotic resistance, evidence of more effective treatments is lacking in China, where H. pylori prevalence is nearly 50%. Thus, we performed a network meta-analysis to compare therapeutic regimens.
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Cold Endoscopic Mucosal Resection (c-EMR) of Nonpedunculated Colorectal Polyps ≥20 mm: A Systematic Review and Meta-analysis. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-12-27 Daryl Ramai, Benjamin Clement, Marcello Maida, Melissa Previtera, Olivia W Brooks, Yichen Wang, Saurabh Chandan, Banreet Dhindsa, Smit Deliwala, Antonio Facciorusso, Mouen Khashab, Andrew Ofosu
There is increasing evidence that cold endoscopic mucosal resection (c-EMR) can effectively treat large colorectal polyps. We aim to appraise the current literature and evaluate outcomes following c-EMR for nonpedunculated colonic polyps ≥20 mm.
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Large Single-center Experience with Long-term Outcomes of EUS-guided Transmural Gallbladder Drainage. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-12-22 Judy A Trieu, Andrew J Gilman, Kelly Hathorn, Todd H Baron
To describe the long-term outcomes of patients after EUS-guided gallbladder drainage (EUS-GBD), including those who underwent standardized stent exchanges for permanent plastic stents.
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A Preliminary Controlled Trial of Endoscopic Ultrasound-guided Fiducial Markers to Guide Pancreas Surgery. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-12-19 Patrick W Chang, Jonathan Sadik, Ara B Sahakian, Ravi Kankotia, Christopher Ko, Jessica Serna, Alex Rodriguez, Helen Lee, Sujit Kulkarni, Yuri Genyk, Mohd Sheikh, James L Buxbaum
Endoscopic ultrasound (EUS) is routinely used for fiducial marker placement (FMP) to guide stereotactic radiation of pancreatic tumors, but EUS-FMP explicitly to guide surgery has not been studied in a prospective, controlled manner. Multipurpose EUS systems have been developed that facilitate simultaneous EUS-FMP at the time of biopsy. We aimed to evaluate the feasibility of EUS-FMP to guide pancreatic
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Plasma Interleukin-13 Levels Correlate With the Severity of Symptoms Induced by Functional Dyspepsia. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-12-15 Marcos Leites, Carolina Olano, Teresa Freire
Functional dyspepsia (FD) is a gastrointestinal functional disorder of the upper gastrointestinal tract that affects the quality of life of patients and poses a significant economic burden. It has been proposed that the local inflammatory immune response at the duodenum is associated with an increase in intestinal permeability, favoring the recruitment of Th2 cells and granulocyte degranulation. Moreover
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Age Matters: Adenoma Detection Rates in Average-risk Screening Patients Aged 45 to 49 Compared With Those Aged 50 to 54. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-12-08 Shuji Mitsuhashi, Jade Azari, Vincent Dioguardi, Justin Bilello, Marshall Tang, David Kastenberg
This study aims to address gaps in medical knowledge by determining whether adenoma detection rate (ADR) in average-risk screening patients aged 45 to 49 is equivalent to screening patients aged 50 to 54.
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The Value of Liver Biopsy and Histology in Liver Disease Diagnosis and Patient Care-a Pragmatic Prospective Clinical Practice Study. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-12-04 Ali Khalifa, Don C Rockey
We aimed to examine the correlation of pre-biopsy clinical diagnosis with hepatic histopathology.
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Esophageal Function Testing Patterns in the Evaluation and Management of Lung Transplantation: Results of a National Survey. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-12-04 Marilyn Yamamoto, Afrin N Kamal, Scott Gabbard, John Clarke, C Prakash Gyawali, David A Leiman
We surveyed esophageal motility laboratories affiliated with adult pulmonary transplant centers to determine esophageal function testing (EFT) practices.
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Fecal Microbiota, Live-jslm for the Prevention of Recurrent Clostridioides difficile Infection: Subgroup Analysis of PUNCH CD2 and PUNCH CD3. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-11-30 Paul Feuerstadt, Carl V Crawford, Xing Tan, Victoria Pokhilko, Lindy Bancke, Samson Ng, Beth Guthmueller, Monique R Bidell, Glenn Tillotson, Stuart Johnson, Andrew M Skinner
To assess fecal microbiota, live-jslm (REBYOTA, abbreviated as RBL, formerly RBX2660) efficacy and safety in participants grouped by recurrent Clostridioides difficile infection (rCDI) risk factors and treatment-related variables.
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Cold Versus Hot Endoscopic Mucosal Resection for Sessile Serrated Colorectal Polyps ≥10 mm: A Systematic Review and Meta-analysis. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-11-29 Talia F Malik, Babu P Mohan, Smit Deliwala, Lena L Kassab, Saurabh Chandan, Neil R Sharma, Douglas G Adler
We performed a systematic review and meta-analysis studying the efficacy and safety of cold versus hot endoscopic mucosal resection (EMR) for resection of sessile serrated polyps (SSPs) ≥10 mm.
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Change in Biologic Class Promotes Endoscopic Remission Following Endoscopic Postoperative Crohn's Disease Recurrence. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-11-27 Salam P Bachour, Ravi S Shah, Abel Joseph, Hareem Syed, Adel Hajj Ali, Florian Rieder, Edward L Barnes, Jordan Axelrad, Stefan D Holubar, Miguel Regueiro, Benjamin L Cohen, Benjamin H Click
Assess the outcomes of various therapeutic regimens to treat initial endoscopic postoperative recurrence despite biologic prophylaxis.
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Symptom Outcomes of Celiac Disease in Those on a Gluten-free Diet. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-11-27 Isabel A Hujoel, Margaux L A Hujoel, Rok Seon Choung, Joseph A Murray
We aimed to evaluate symptom outcomes in those on a gluten-free diet during the 5 years after diagnosis.
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Disparities in Rates of Multitarget Stool DNA Test Completion for Colorectal Cancer Screening. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-11-27 Jeffrey Dong, Hyder Said, Samuel J Miller, Hannah K Systrom, Joseph D Feuerstein
The aim was to assess patient adherence to multitarget stool DNA testing as well as factors associated with adherence.
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Comparing EUS-directed Transgastric ERCP (EDGE) Versus Laparoscopic-Assisted ERCP Versus Enteroscopic ERCP: A Network Meta-analysis. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-11-24 Manesh K Gangwani, Muhammad Aziz, Hossein Haghbin, Amna Iqbal, Julia Dillard, Dushyant S Dahiya, Hassam Ali, Umar Hayat, Sadik Khuder, Wade Lee-Smith, Yusuf Nawras, Faisal Kamal, Sumant Inamdar, Yaseen Alastal, Nirav Thosani, Douglas Adler
Management of choledocholithiasis in patients with Roux-en-Y gastric bypass surgery is challenging. This study aims to compare technical success rates, adverse events, and procedural time between 3 current approaches: endoscopic ultrasound-directed transgastric Endoscopic retrograde cholangiopancreatography (ERCP) (EDGE), enteroscopy-assisted ERCP (E-ERCP), and laparoscopic-assisted ERCP (LA-ERCP)
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Safety of Percutaneous Endoscopic Jejunostomy Placement Compared With Surgical and Radiologic Jejunostomy Placement: A Nationwide Inpatient Assessment. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-11-24 Daryl Ramai, Joseph Heaton, John Fang
We compared the safety and outcomes of percutaneous jejunostomy tubes placed endoscopically (PEJ), fluoroscopically by interventional radiology (IR-jejunostomy), and open jejunostomy placed surgically (surgical jejunostomy).
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Representation of Racial Minorities in the United States Colonoscopy Surveillance Interval Guidelines. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-11-23 Shaharyar A Zuberi, Lauren Burdine, Jeffrey Dong, Joseph D Feuerstein
Clinical guidelines should ideally be formulated from data representative of the population they are applicable to; however, historically, studies have disproportionally enrolled non-Hispanic White (NHW) patients, leading to potential inequities in care for minority groups. Our study aims to evaluate the extent to which racial minorities were represented in the United States Colorectal Cancer Surveillance
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Impact of Slim Linear Echoendoscope on the Practice of EUS. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-11-21 Ji Young Bang, Philippe Willems, Udayakumar Navaneethan, Robert Hawes, Shyam Varadarajulu
Standard linear echoendoscopes have a large distal tip and bending radius, which can preclude adequate examination in some patients.
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Quality of Pancreatic Cyst Clinical Practice Guidelines. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-11-16 Jason J John, Wojciech Blonski, Tea Reljic, Ambuj Kumar
There are various published clinical practice guidelines (CPGs) for the management of pancreatic cystic lesions. However, the quality of these guidelines has not been systematically appraised. This study aimed to evaluate the quality of CPGs published in the last 5 years for the management of pancreatic cysts.
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FIB-4 as a Time-varying Covariate and Its Association With Severe Liver Disease in Primary Care: A Time-dependent Cox Regression Analysis. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-11-16 Andrew D Schreiner, Jingwen Zhang, William P Moran, David G Koch, Justin Marsden, Sherry Livingston, Chloe Bays, Patrick D Mauldin, Mulugeta Gebregziabher
The Fibrosis-4 Index (FIB-4) has demonstrated a strong association with severe liver disease (SLD) outcomes in primary care, but previous studies have only evaluated this relationship using 1 or 2 FIB-4 scores. In this study, we determined the association of FIB-4 as a time-varying covariate with SLD risk using time-dependent Cox regression models.
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Application of a Machine Learning Predictive Model for Recurrent Acute Pancreatitis. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-11-03 Wensen Ren, Kang Zou, Yuqing Chen, Shu Huang, Bei Luo, Jiao Jiang, Wei Zhang, Xiaomin Shi, Lei Shi, Xiaolin Zhong, Muhan Lü, Xiaowei Tang
Acute pancreatitis is the main cause of hospitalization for pancreatic disease. Some patients tend to have recurrent episodes after experiencing an episode of acute pancreatitis. This study aimed to construct predictive models for recurrent acute pancreatitis (RAP).
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FIB-4 Reliability in Patients With Severe Obesity: Lower Cutoffs Needed? J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-11-03 Victoria Green, Joanne Lin, Morgan McGrath, Aaron Lloyd, Pearl Ma, Kelvin Higa, Marina Roytman
Liver biopsy is the gold standard to evaluate hepatic fibrosis; however, it has many drawbacks, especially in patients with severe obesity. Noninvasive testing such as the FIB-4 score is increasingly being used as the initial screening tool to identify patients at risk for advanced fibrosis. The broader applicability of FIB-4 and the precision of its cutoff values remain uncertain in metabolic dysfunction-associated
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Outcomes of Endoscopic Ultrasound-guided Fine Needle Biopsy Using a Novel Hydrostatic Stylet Tissue Acquisition Technique. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-10-27 Patrick T Magahis, Donevan Westerveld, Malorie Simons, David L Carr-Locke, Kartik Sampath, Reem Z Sharaiha, SriHari Mahadev
Endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) is frequently used to obtain core samples of solid lesions. Here, we describe and evaluate a novel hydrostatic stylet (HS) technique designed to optimize core sample acquisition, reporting diagnostic yield, efficacy, and safety relative to the conventional stylet slow-pull (SP) technique.
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The Impact of Race and Sex on the Clinical Outcomes of Homeless Patients With Alcoholic Liver Disease: Propensity Score Matched Analysis of US Hospitals. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-10-23 David U Lee, Jean Kwon, John Han, Kevin Chang, Sindhura Kolachana, Aneesh Bahadur, Ki Jung Lee, Gregory H Fan, Raza Malik
Among patients with alcoholic liver disease (ALD), homelessness poses significant medical and psychosocial risks; however, less is known about the effects of race and sex on the hospital outcomes of admitted homeless patients with ALD.
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Endoscopic Glue Injection Versus Endoscopic Human Thrombin Injection for Bleeding Gastric Varices-A Randomized Controlled Trial. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-10-12 Ashok Jhajharia, Prachis Ashdhir, Gireesh Dhaked, Hitesh Sharma
Acute gastric variceal bleeding (AGVB) is a potentially fatal consequence of portal hypertension, accounting for 10% to 30% of all variceal bleeding. Although endoscopic cyanoacrylate glue injection is a common treatment for acute hemostasis, it has been linked to significant side effects. In the treatment of AGVB, there is limited evidence of the efficacy and relative safety of endoscopic human thrombin
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COVID-19 Pandemic is Associated With Increased Prevalence of GERD and Decreased GERD-related Quality of Life: Analysis From 9800 Participants in the Indonesian GERD-Q Study. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-10-02 Ahmad Fauzi, Daniel M Simadibrata, Dewi Friska, Ari F Syam
The prevalence of gastroesophageal reflux disease (GERD) is expected to increase during the pandemic due to unexpected, sudden lifestyle changes such as decreased physical activity and worsening mental conditions. Here, we aim to explore the difference in the prevalence of GERD and GERD-related quality of life (QoL) in Indonesia during the COVID-19 pandemic compared with before the COVID-19 pandemic
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Inpatient Outcomes of Gastric Antral Vascular Ectasia in Those With Aortic Stenosis: A Retrospective Study of 85,000 Hospitalizations. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-10-02 Mohammad Aldiabat, Yassine Kilani, Majd Alahmad, Laith Alhuneafat, Yazan Aljabiri, Ali Horoub, Khaled Alabdallah, Hebah Alrahamneh, Amar Manvar
To investigate the outcomes of hospitalized patients with gastric antral vascular ectasia (GAVE) in the setting of aortic stenosis (AS).
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The Trends in Health Care Utilization and Costs Associated With Primary Liver Cancer: An Analysis of United States Hospitals Between 2016 and 2019. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-09-29 David U Lee, Elyse A Adonizio, David J Hastie, Reid Ponder, Ki Jung Lee, Daniel Jung, Gregory H Fan, Raza Malik
Primary liver cancer (PLC) has placed an increasing economic and resource burden on the health care system of the United States. We attempted to quantify its epidemiology and associated costs using a national inpatient database.
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Efficacy of Antiobesity Medications in Patients With Celiac Disease on a Gluten-free Diet: A Retrospective Matched Cohort Study. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-09-28 Diego Anazco, Sima Fansa, Wissam Ghusn, Khushboo Gala, Bryan Nicolalde, Elif Tama, Gerardo Calderon, Adam C Bledsoe, Maria D Hurtado, Joseph A Murray, Andres Acosta
We aim to describe the weight loss outcomes of patients with celiac disease (CeD) taking antiobesity medications (AOMs) and compare it with the weight loss outcomes of patients without CeD taking AOMs.
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Trends and Variations in Pancreatic Cancer Mortality Among US Metro and Nonmetro Adults, 1999-2020. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-09-28 Samuel Ma, Itunu O Sokale, Aaron P Thrift
Pancreatic cancer is the third leading cause of cancer deaths in the United States. Despite decreasing cancer mortality rates as a whole, pancreatic cancer death rates in the United States remain steady and demonstrate racial/ethnic disparities. Divergent cancer mortality trends have also been observed between metro and nonmetro populations. We therefore aimed to compare metro and nonmetro trends in
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Performance of OC-Auto Micro 80 Fecal Immunochemical Test in an Integrated Academic-Community Health System. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-09-26 Lindsey Durowoju, Patrick C Mathias, Ari Bell-Brown, Nathan Breit, Hsuan-Chieh Liao, Wynn Burke, Rachel B Issaka
We aimed to determine the performance of the OC-Auto Micro 80 fecal immunochemical test (FIT) in an average-risk population receiving care in an integrated, academic-community health system.
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Validation of the Modified Location-based Resect-and-discard Strategy Requiring Pathology Examination of Sigmoid Diminutive Polyps. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-09-22 Zhiyu Dong, Qiongmei Zhang, Ye Chen, Xue Qian, Ying Chen, Shuchang Xu
Recently, the location-based resect-and-discard (LBRD) strategy, which does not depend on optical diagnosis, was developed and demonstrated different surveillance interval agreement with the pathology-based reference in several researches. We aimed to evaluate the performance of LBRD in our first-time colonoscopy cohort, and improve the LBRD.
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A Review of Helicobacter pylori Diagnostics in Africa: From the Bedside to the Laboratory. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-09-15 Timothy Archampong, Kenneth Tachi, Amoako Duah
Helicobacter pylori (H. pylori) is endemic in Africa with a prevalence estimate of 79.1%. In addition, there is a significant community burden of dyspepsia in Africa, similar to other western countries. However, the majority of infected persons do not manifest the disease. In Africa, for instance, peptic ulcer disease is prevalent, whereas gastric cancer has reportedly low incidence. Therefore, it
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Prediction of in-hospital Mortality of Intensive Care Unit Patients with Acute Pancreatitis Based on an Explainable Machine Learning Algorithm. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-09-15 Wensen Ren, Kang Zou, Shu Huang, Huan Xu, Wei Zhang, Xiaomin Shi, Lei Shi, Xiaolin Zhong, Yan Peng, Xiaowei Tang, Muhan Lü
Acute pancreatitis (AP) is potentially fatal. Therefore, early identification of patients at a high mortality risk and timely intervention are essential. This study aimed to establish an explainable machine-learning model for predicting in-hospital mortality of intensive care unit (ICU) patients with AP.
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Mild Thrombocytopenia, a Predictor of Outcomes After Laparoscopic Cholecystectomy: Assessment of Surgical Risk in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease. J. Clinical Gastroenterol. (IF 2.9) Pub Date : 2023-09-14 William S Reiche, Ryan W Walters, Bryce F Schutte, Sandeep Mukherjee, Haitam M Buaisha
A common cause of mild thrombocytopenia is chronic liver disease, the most common etiology being metabolic dysfunction-associated steatotic liver disease (MASLD). Mild thrombocytopenia is a well-defined, independent marker of hepatic fibrosis in patients with chronic liver disease. Currently, there is a paucity of information available to characterize perioperative risk in patients with MASLD; therefore