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Trends in all-cause and cause-specific mortality in older adults with and without diabetes: a territory-wide analysis in one million older adults in Hong Kong Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-03-14 Aimin Yang, Tingting Chen, Mai Shi, Eric Lau, Raymond SM Wong, Jones Chan, Juliana CN Chan, Elaine Chow
Direct comparisons of population-level trends in all-cause and cause-specific mortalities among older adults with and without diabetes are lacking. We performed a territory-wide analysis of 1,142,000 unique older adults aged ≥65 years (31.7% with diabetes) with at least one attendance in the Hong Kong Hospital Authority in 2014-2018. We used Joinpoint regression to describe trends of age- and sex-standardised
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The effect of subcutaneous Lixisenatide on weight loss in patients with type 2 Diabetes Mellitus: Systematic review and Meta-Analysis of randomized controlled trials Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-03-14 Lei Sheng, Meixian Deng, Xin Li, Huang Wan, Changjiang Lei, Kousalya Prabahar, Benjamin Hernández-Wolters, Hamed Kord-Varkaneh
The impacts of subcutaneous Lixisenatide on body weight in patients with type 2 DM, remain inadequately understood; consequently, this systematic review and -regression analysis of randomized controlled trials (RCTs) was conducted to evaluate the influence of subcutaneous Lixisenatide administration on BW and BMI values in individuals with Type 2 diabetes. A comprehensive literature search was conducted
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The role of sex on the prevalence of cardiovascular risk factors in children and adolescents with Type 1 diabetes: The SWEET international database Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-03-13 Marco Marigliano, Stefanie Lanzinger, Imane Zineb, Consuelo Barcala, Amy S. Shah, Jannet Svensson, Kaloyan Tsochev, Artur Mazur, Assimina Galli-Tsinopoulou, Sorin Ioacara, Kesavadev Jothydev, Claudio Maffeis
To assess the prevalence of cardiovascular risk factors (CVRFs) in children and adolescents with type 1 diabetes (T1D) in the International SWEET registry and the possible role of clinical variables in modifying the risk of having single or multiple CVRFs. The study is a cross-sectional study. Cut-off points for CVRFs were fixed according to International Society for Pediatric and Adolescent Diabetes
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Outcomes of the Dulce Digital-COVID Aware (DD-CA) discharge texting platform for US/Mexico border Hispanics with diabetes Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-03-12 Samantha R. Spierling Bagsic, Addie L. Fortman, Emily Rose N. San Diego, Emily C. Soriano, Rebekah Belasco, Haley Sandoval, Alessandra Bastian, Olivia M. Padilla Neely, Laura Talavera, Eric Leven, Nicole Evancha, Athena Philis-Tsimikas
Hispanics have higher type 2 diabetes (T2D) prevalence, poorer outcomes, and are disproportionately affected by COVID-19. Culturally-tailored, diabetes educational text messaging has previously improved HbA1c in this population. During the pandemic, hospitalized Hispanic adults with T2D (N = 172) were randomized to receive Dulce Digital-COVID Aware (“DD-CA”) texting platform upon discharge plus diabetes
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Impact of short-term application of continuous glucose monitoring system(CGMS) on long-term glycemic profile in adolescents and adults with type 1 diabetes mellitus: An open-label randomized control cross over study Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-03-12 Ashish Gupta, Soham Mukherjee, Sanjay Kumar Bhadada, Sant Ram, Rimesh Pal, Naresh Sachdeva, Pinaki Dutta
The use of Continuous Glucose Monitoring System (CGMS) improves glycemic parameters in Type 1 Diabetes Mellitus (T1D), but the cost is prohibitive. Here, we investigated the effect of short-term application of real-time and intermittently-scanned CGMS (rt and is-CGMS) in T1D individuals on change in HbA1c at the end of 3 months. T1D individuals were randomized into three groups in a ratio of 1:1:2
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Innovations: Using telemedicine to improve care of predominantly non-white youth with suboptimal insulin dependent diabetes control Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-03-12 Lisa Rasbach, Ginna Purrington, Deanna Adkins, Robert Benjamin
Despite advances in diabetes treatments, youth commonly fail to meet glucose targets. Telehealth support may help youth meet diabetes related goals. The objective of the project was to assess whether intensive telehealth support in a group of poorly controlled youth with diabetes would help improve glycated hemoglobin (HbA1c) levels and decrease hospitalization rates over a 12-month time frame. This
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Not enough known about fenofibrate’s kidney effects in people with Type 2 diabetes Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-03-11 Alicia J. Jenkins, Rachel L. O'Connell, Andrzej S. Januszewski, Angela C. Webster, Timothy M.E. Davis, Meg J. Jardine, Russell Scott, Marja-Riitta Taskinen, Anthony C. Keech, On Behalf of the FIELD Trial Study Group
Globally ≈10% of adults have diabetes, with 80% in disadvantaged regions, hence low-cost renoprotective agents are desirable. Fenofibrate demonstrated microvascular benefits in several cardiovascular end-point diabetes trials, but knowledge of effects in late-stage kidney disease is limited. We report new FIELD substudy data and call for further kidney outcomes data.
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Accuracy of intermittently scanned continuous glucose monitoring during caesarean delivery in pregnant women with insulin-treated diabetes Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-03-11 Fabrizia Citro, Cristina Bianchi, Michele Aragona, Tommaso Belcari, Lorella Battini, Piero Marchetti, Alessandra Bertolotto
Continuous Glucose Monitoring (CGM) systems are not currently recommended to guide intrapartum glucose and insulin infusion, due to insufficient data. In this study, intrapartum accuracy of intermittently scanned CGM (isCGM), compared to simultaneously measured capillary glucose (CG), was evaluated. Paired isCGM () - CG data during caesarean delivery in pregnant women with insulin-treated diabetes
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The hidden epidemic: Uncovering incidental fatty liver disease and its metabolic comorbidities by datamining in a hospital data lake – A real-world cohort study Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-03-11 Iiro P. Karhiaho, Samu H. Kurki, Helka I. Parviainen, Liisa Kullamaa, Martti A. Färkkilä, Niina Matikainen, Tiinamaija Tuomi
To identify individuals with incidental fatty liver disease (FLD), and to evaluate its prevalence, metabolic co-morbidities and impact on follow-up. We leveraged the data-lake of Helsinki Uusimaa Hospital district (Finland) with a population of 1.7 million (specialist and primary care). A phrase recognition script on abdominal imaging reports (2008–2020) identified/excluded FLD or cirrhosis; we extracted
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Hospitalisation for herpes zoster in people with and without diabetes: A 10-year-observational study Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-03-08 Carlo B. Giorda, Roberta Picariello, Barbara Tartaglino, Elisa Nada, Francesco Romeo, Giuseppe Costa, Roberto Gnavi
This study explores the association between Herpes Zoster (HZ) hospitalizations and diabetes in Piedmont, Italy from 2010 to 2019. Focusing on the burden of HZ hospitalizations in diabetic and non-diabetic groups, it aims to identify risk factors in diabetics to enhance prevention strategies. In a two-phase study, we first compared age-standardized HZ hospitalization rates between diabetic and non-diabetic
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The association between patterns of weight change, diabetes status and glycaemia among adults with overweight and obesity Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-03-06 Ruoyu Yin, Amy L. Ahern, Louise Lafortune, Simon J. Griffin, Jean M. Strelitz, Julia Mueller
To investigate the associations between weight change patterns and 5-year incident non-diabetic hyperglycaemia (NDH), and glycated haemoglobin (HbA) levels among individuals who had overweight or obesity. This longitudinal cohort study (N = 435) pooled data from a weight management trial. Participants were adults with a body mass index of ≥28 kg/m. They were categorised as “no weight loss”, “maintainers”
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Correlational analysis of PLIN1 with inflammation in diabetic foot ulcer wounds Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-03-06 Mengting Wang, Xiaoliang Cao, Yanxing Shang, Yasu Jiang, Peng Chen, Chengwei Duan, Dongmei Zhang, Ping Wang, Jianfeng Ji, Zhenhua Gong
The persistent presence of inflammation is a recognized pathogenic mechanisms of diabetic foot ulcers (DFUs). We aimed to investigate the expression of PLIN1 in tissues from DFU patients and assess its potential association with inflammation-induced damage. We performed transcriptome sequencing and correlation analysis of the foot skin from patients with or without DFUs. Additionally, we examined the
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Consistent glycaemic efficacy and safety of concomitant use of iGlarLixi and sodium-glucose co-transporter-2 inhibitor therapy for type 2 diabetes: A patient-level pooled analysis of three randomised clinical trials Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-03-05 Francesco Giorgino, Cristian Guja, Hasan Aydın, Felipe Lauand, Lydie Melas-Melt, Julio Rosenstock
Sodium glucose co-transporter 2 inhibitors (SGLT2is) and/or glucagon-like peptide-1 receptor agonists (GLP-1 RAs) with proven cardio- and reno-protective benefits are recommended in people with type 2 diabetes (T2D) at high risk of cardiovascular disease, chronic kidney disease, and/or heart failure. This pooled analysis compared efficacy and safety outcomes of iGlarLixi with or without SGLT2is in
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Higher Mortality and Longer Length of Stay in Hospitalized Patients with Newly Diagnosed Diabetes Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-03-02 Seol A Jang, Kyoung Min Kim, Hye Jin Kang, Seok-Jae Heo, Chul Sik Kim, Seok Won Park
We investigated the association between diabetes status at admission and in-hospital outcomes in all hospitalized patients, regardless of the reason for admission. All individuals aged 20 years or older who were admitted to Yongin Severance Hospital between March 2020 and February 2022 were included in study. Subjects were categorized into three groups: non-DM, known DM, and newly diagnosed DM, based
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Carbohydrate counting knowledge and ambulatory glucose profile in persons living with type 1 diabetes Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-03-02 Sopio Tatulashvili, Bleuenn Dreves, Laurent Meyer, Emmanuel Cosson, Michael Joubert
Context. In this multicenter prospective study, the GluciQuizz questionnaire was used to evaluate carbohydrate knowledge. CGM data for the 14 days preceding completion of the questionnaire were analyzed. The mean age of the 170 participants was 40.7 ± 14.8 years and duration of T1D 18.8 ± 12.1 years. The mean GluciQuizz total score for all participants was 66 ± 13 %. Mean TIR was 58.6 ± 18.7 %. GluciQuizz
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Telemedicine maintains good glucose control in children with type 1 diabetes but is not time saving for healthcare professionals: KITES randomized study Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-03-02 Lukas Plachy, Vit Neuman, Katerina Velichova, Matvei G. Slavenko, Alzbeta Santova, Shenali Anne Amaratunga, Barbora Obermannova, Stanislava Kolouskova, Stepanka Pruhova, Zdenek Sumnik, Lenka Petruzelkova
To evaluate glucose control non-inferiority and time benefits of telemedicine follow-up in children with type 1 diabetes (CwD). In a single-center 9-month-long randomized controlled study ( NCT05484427), 50 children were randomized to either telemedicine group (TG) followed-up distantly by e-mail, or to face-to-face group (FFG) attending standard personal visits. The primary endpoint was non-inferiority
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Stress hyperglycemia ratio linked to worse prognosis in Cardiac Intensive Care Unit patients: A retrospective observational study Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-03-01 Qianqian Zhang, Huaqiang Xiang, Qianqian Xu, Zesong Hu, Yangjing Xue, Jie Wang, Kangting Ji
This study aimed to delineate correlation between stress hyperglycemia ratio (SHR) and clinical outcomes among patients in the cardiac intensive care unit (CICU). Participants were categorized based on their SHR threshold values. Key outcomes were short-term mortality and major adverse cardiovascular events (MACEs) at 1-year follow-up. The association between SHR and outcomes was estimated using inverse
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Should insulin needles be used once or several times? An unresolved conundrum Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-28 Sandro Gentile, Felice Strollo
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Relationships of hypoglycemia awareness, hypoglycemia beliefs, and continuous glucose monitoring glycemic profiles with anxiety and depression symptoms in adults with type 1 diabetes using continuous glucose monitoring systems Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-28 Yu Kuei Lin, Emily Hepworth, Nicole de Zoysa, Jessica McCurley, Mary Ellen Vajravelu, Wen Ye, Gretchen A. Piatt, Stephanie A. Amiel, Simon J. Fisher, Rodica Pop-Busui, James E. Aikens
To evaluate relationships of hypoglycemia awareness, hypoglycemia beliefs, and continuous glucose monitoring (CGM) glycemic profiles with anxiety and depression symptoms in adults with type 1 diabetes (T1D) who use CGM. A cross-sectional survey and data collections were completed with 196 T1D adults who used CGM (59% also used automated insulin delivery devices (AIDs)). We assessed hypoglycemia awareness
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Real-world outcomes of Omnipod DASH system use in people with type 1 diabetes: Evidence from the Association of British Clinical Diabetologists (ABCD) study Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-27 Alexandros L. Liarakos, Nebras Hasan, Thomas S.J. Crabtree, Lalantha Leelarathna, Peter Hammond, Sufyan Hussain, Masud Haq, Aisha Aslam, Erneda Gatdula, Fraser W Gibb, Alistair Lumb, Kirsty Bull, Eswari Chinnasamy, Giorgio Carrieri, David M. Williams, Pratik Choudhary, Robert E.J. Ryder, Emma G. Wilmot
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Assessing the impact of pregnancy planning on obstetric and perinatal outcomes in women with pregestational diabetes mellitus Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-27 Angel Chimenea, Ana María Calderón, Guillermo Antiñolo, Eduardo Moreno-Reina, Lutgardo García-Díaz
We investigated the role of pregnancy planning in improving glycemic control and its potential impact on the overall pregnancy outcomes, obstetric outcomes, and perinatal well-being in women with pregestational diabetes mellitus (PGDM). A retrospective observational cohort study was conducted, including all pregnant women with PGDM treated in our center 2012 and 2018. Among 425 participants, 26.6 %
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Non-pharmacological interventions to improve cardiovascular risk factors in people with diabetic foot disease: A systematic review and meta-analysis Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-24 Patrick Highton, Abdullah Almaqhawi, Maroria Oroko, Harini Sathanapally, Laura Gray, Melanie Davies, David Webb, Frances Game, John Petrie, Solomon Tesfaye, Jonathan Valabhji, Clare Gillies, Kamlesh Khunti
Cardiovascular disease (CVD) risk in those with diabetic foot disease is very high. Non-pharmacological interventions may improve this risk, though no previous evidence synthesis has been completed. This systematic review aimed to investigate the impact of non-pharmacological interventions on CVD risk factors in diabetic ulcer disease.
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Effect of low dose Semaglutide in people with Type 1 Diabetes and excess weight Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-24 Bruno A. Grassi, María Teresa Onetto, Camila Sánchez, Nicole Tapia, Francisca Mena
Obesity is a prevalent problem in people living with T1D (PwT1D), and it has been linked to cardiovascular disease in this population. The use of low dose weekly Semaglutide (0,5 mg) was evaluated in a cohort of PwT1D and excess weight.
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Association between antidepressants and the risk of diabetic foot ulcers and amputation in antidepressant-naïve type 2 diabetes mellitus patients: A nested case-control study Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-24 Jinhyun Kim, Kyungduk Hurh, Seokmoon Han, Hyunkyu Kim, Eun-Cheol Park, Suk-Yong Jang
Antidepressants are widely used by individuals with type 2 diabetes mellitus (T2DM). This study aimed to explore the correlation between antidepressant use, considering specific antidepressant subclasses or cumulative doses, and diabetic foot ulcer (DFU) risk. This nested case-control study was conducted using a representative population-based Korean cohort database from 2002 to 2019. Participants
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The presence of exudative thickening of Bowman’s capsule predict poor prognosis in diabetic kidney disease Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-24 Jiayue Lu, Kewei Xie, Xiajing Che, Ahui Song, Minfang Zhang, Chaojun Qi, Renhua Lu, Ying Fan, Nan Liu, Zhaohui Huang, Yali Peng, Qiuling Fan, Niansong Wang, Li Yao, Leyi Gu
The relationship between Bowman's capsule thickening and progression of diabetic kidney disease (DKD) remains uncertain. Renal biopsy specimens from 145 DKD patients and 20 control subjects were evaluated for Bowman's capsule thickness. Immunohistochemical staining assessed col4α2, laminin β1, and albumin expression. In a discovery cohort of 111 DKD patients with eGFR ≥ 30 ml/min/1.73 m, thickening
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Visceral adipose tissue and risk of diabetic nephropathy: A Mendelian randomization study Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-15 Min Tao, Guanghong Zhou, Jing Liu, Miao He, Xie Luo, Cong Wang, Lili Zhang
Previous observational studies have established a correlation between visceral adipose tissue (VAT) and diabetic nephropathy (DN). However, the causality of this association remains unclear. Therefore, the aim of this study was to investigate the causal association between VAT and DN by employing two-sample Mendelian randomization (MR) methods. The primary MR approach employed was the random-effects
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Metabolic dysfunction-associated fatty liver disease increases the risk of type 2 diabetes mellitus in young Korean adults Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-15 Junchul Ha, Oak-Kee Hong, Kyungdo Han, Hyuk-Sang Kwon
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Vitamin D deficiency increases the risk of diabetic peripheral neuropathy in elderly type 2 diabetes mellitus patients by predominantly increasing large-fiber lesions Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-15 Sijia Fei, Jingwen Fan, Jiaming Cao, Huan Chen, Xiaoxia Wang, Qi Pan
This study explores the link between Vitamin D deficiency (VDD) and diabetic peripheral neuropathy (DPN) in elderly type 2 diabetes mellitus (T2DM) patients. Involving 257 elderly T2DM patients, the study utilized propensity score matching to balance age, sex, and diabetes duration. VDD was defined as serum 25-hydroxyvitamin D [25(OH)D] levels below 20 ng/ml. Large nerve fiber lesions were evaluated
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Intersectional identities play a role in perceived discrimination for families living with type 1 diabetes Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-14 Ananta Addala, Ricardo Medina Penaranda, Diana Naranjo, David M Maahs, Korey K Hood
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Prevalence of maternal hyperglycemic subtypes by race/ethnicity and associations between these subtypes with adverse pregnancy outcomes: Findings from a large retrospective multi-ethnic cohort in the United States Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-14 Xinyue Liu, Carla Janzen, Yeyi Zhu, Marissa Seamans, Zhe Fei, Roch Nianogo, Liwei Chen
With the two-step gestational diabetes mellitus (GDM) screening approach, hyperglycemic subtypes can be identified. We aimed to investigate racial/ethnic differences in the prevalence of hyperglycemic subtypes and to examine the associations between these subtypes and adverse pregnancy outcomes. In this retrospective cohort, 11,405 pregnancies were screened using the two-step approach. Hyperglycemic
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Effects of ADHD and ADHD treatment on glycemic management in type 1 diabetes: A systematic review and meta-analysis of observational studies Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-13 Ali Zare Dehnavi, Islam Elmitwalli, Hisham O.H. Alsharif, Ali Shervin Razavi, Tyler A. Gumpel, Abigail Smith, Ruth S. Weinstock, Stephen V. Faraone, Yanli Zhang-James
Studies suggested a higher prevalence of Attention-deficit/hyperactivity disorder (ADHD) in individuals with Type 1 Diabetes Mellitus (T1D). However, it is unclear how ADHD impacts glycemia and diabetes-related complications. This systematic review and meta-analysis aimed to investigate the effect of ADHD and ADHD medications on HbA1c and acute complications in T1D. A literature search was conducted
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Association between inflammatory biomarkers and mortality in individuals with type 2 diabetes: NHANES 2005–2018 Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-11 Jiaqi Zhang, Xiaoting Fan, Yan Xu, Kaiyuan Wang, Tong Xu, Tianyang Han, Chengxiang Hu, Runhong Li, Xinli Lin, Lina Jin
This study aimed to examine independent association between inflammatory biomarkers and all-cause mortality as well as cardio-cerebrovascular disease (CCD) mortality among U.S. adults with diabetes. A cohort of 6412 U.S. adults aged 20 or older was followed from the start until December 31, 2019. Statistical models such as Cox proportional hazards model (Cox) and Kaplan-Meier (K-M) survival curves
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Associations between thyroid hormones and appendicular skeletal muscle index, and hand grip strength in people with diabetes: The KAMOGAWA-A study Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-11 Shinnosuke Hata, Hiroshi Okada, Megumi Minamida, Junya Hironaka, Yuka Hasegawa, Yuriko Kondo, Hanako Nakajima, Nobuko Kitagawa, Takuro Okamura, Yoshitaka Hashimoto, Takafumi Osaka, Noriyuki Kitagawa, Saori Majima, Takafumi Senmaru, Emi Ushigome, Naoko Nakanishi, Mai Asano, Masahide Hamaguchi, Michiaki Fukui
To assess the effects of thyroid hormones on appendicular skeletal muscle index (SMI) and hand grip strength (HGS) in people with diabetes. This cross-sectional cohort included 1,135 participants with diabetes admitted to 3 hospitals in Japan. Multiple regression analysis was performed to determine the associations among thyroid hormone levels, SMI, and HGS. Of the 1,135 participants, 480 were female
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A literature review of quality assessment and applicability to HTA of risk prediction models of coronary heart disease in patients with diabetes Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-10 Li Jiu, Junfeng Wang, Francisco Javier Somolinos-Simón, Jose Tapia-Galisteo, Gema García-Sáez, Mariaelena Hernando, Xinyu Li, Rick A. Vreman, Aukje K. Mantel-Teeuwisse, Wim G. Goettsch
This literature review had two objectives: to identify models for predicting the risk of coronary heart diseases in patients with diabetes (DM); and to assess model quality in terms of risk of bias (RoB) and applicability for the purpose of health technology assessment (HTA). We undertook a targeted review of journal articles published in English, Dutch, Chinese, or Spanish in 5 databases from 1st
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Safety and effectiveness of iGlarLixi in adults with type 2 diabetes mellitus from Gulf countries during Ramadan holy month: A subgroup analysis of the SoliRam observational study Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-09 Mohamed Hassanein, Adel El Naggar, Abdulrahman Al Sheikh, Khier Djaballah, Mohamed Saeed, Lydie Melas-Melt, Saud AlSifri
To investigate safety and effectiveness of iGlarLixi in adults with type 2 diabetes mellitus (T2DM) observing fast during Ramadan from Gulf countries. This planned subgroup analysis of the SoliRam – a multinational, prospective, non-interventional, real-world, observational study – focused on participants from Gulf countries. Primary endpoint was proportion of participants experiencing ≥1 episode of
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Risk of type 2 diabetes and long-term antibiotic use in childhood: Evidence from the UK Biobank Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-09 Houyu Zhao, Sanbao Chai, Qiaorui Wen, Shengfeng Wang, Siyan Zhan
This study aimed to investigate the association between long-term use of antibiotics during childhood and the risk of type 2 diabetes mellitus (T2DM) using a prospective cohort from the UK Biobank. Participants in the UK Biobank who completed the online survey for digestive health were included in this prospective cohort study. A Cox regression model adjusted for sociodemographic characteristics, general
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The effect of frailty on post-discharge management and outcomes of acute glycaemic crises: Analysis of admissions for hypoglycaemia and hyperglycaemia in Australia Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-09 Jedidiah I. Morton, Jenni Ilomäki, Stephen J Wood, Shin J Liau, Michelle Steeper, Hannah Doody, J Simon Bell
To describe changes in glucose-lowering drug (GLD) dispensing by frailty status for people with diabetes following admission for hypoglycaemia or hyperglycaemia. This study included all people with probable type 2 diabetes in the state of Victoria, Australia, admitted to hospital for hypoglycaemia (n = 2,506 admissions) or hyperglycaemia (n = 1,693) between 1 July 2013 and 29 June 2017. Frailty was
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Are there bidirectional associations between maternal thyroid function and glucose metabolism in singleton live births? A birth cohort study Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-08 Jingru Lu, Linlin Zhu, Yufan Guo, Xuemei Hao, Shuangqin Yan, Fangbiao Tao, Kun Huang
(1) Aims: To examine the associations between maternal thyroid function and glucose metabolism during pregnancy.
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Sleep health predicted glucose metabolism among pregnant women: A prospective cohort study Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-08 Yueying Wang, Pei Chen, Jinle Wang, Qin Lin, Hong Li, Bilgay Izci-Balserak, Jinjin Yuan, Ruru Zhao, Bingqian Zhu
To examine whether sleep health in the first trimester could predict glucose metabolism in the second trimester. Pregnant women (N = 127) during the first trimester were recruited (August 2022 to March 2023). Overall sleep health was assessed by the Sleep Health Index. Various dimensions of sleep health were measured using a 7-day sleep diary and questionnaires. The outcomes, including diagnosis of
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Benefits of 12-month peer support for diabetes self management sustained at 18 months Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-07 Yuexing Liu, Chun Cai, Xiaoyu Wu, Patrick Y. Tang, Muchieh Maggy Coufal, Hongli Chen, Li Shen, Wenya Yu, Yiqing Qian, Samantha Luu, Edwin B. Fisher, Weiping Jia
To evaluate sustainability of peer support (PS) benefits in diabetes management. Supporting a Peer Leader program through Community Health Centers (CHCs) included trainings and consultations from baseline to 12 months. Evaluation at baseline, 12-month, and 18-month follow-up included primary outcome, HbA, and other outcomes of SBP, DBP, LDLc, PHQ-8, diabetes distress, and EQ-5D. 1284 participants with
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Corrigendum to “A High intensity Interval training (running and swimming) and resistance training intervention on heart rate variability and the selected biochemical factors in boys with type 1 diabetes”. [Diabet. Res. Clin. Pract. 204 (2023) 110915] Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-07 Hossein Saki, Farzad Nazem, Farnaz Fariba, Reza Sheikhsharbafan
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Screening for heart failure in patients with diabetes mellitus in tertiary care – A SwissDiab study Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-07 Laura Knaus, Marino Quarella, Marc Buser, Micha T. Maeder, Frida Renström, Michael Brändle
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A multi-state analysis of disease trajectories and mental health transitions in patients with type 2 diabetes: A population-based retrospective cohort study utilizing health administrative data Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-05 Jacopo Lenzi, Rossella Messina, Simona Rosa, Marica Iommi, Paola Rucci, Maria Pia Fantini, Paolo Di Bartolo
To investigate the risk of major depression and dementia in patients with type 2 diabetes, including dementia resulting from depression, and their impact on diabetes-related complications and mortality. We conducted a population-based retrospective cohort study including 11,441 incident cases of diabetes in 2015–2017, with follow-up until 2022. A multi-state survival analysis was performed on a seven-state
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Reply to ‘Glucometric benchmarking to aid refinement of multi-element peri-operative models of care’ Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-03 Gerry Rayman, Emma Page, William K. Gray
Abstract not available
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Interpretable prediction model for assessing diabetes complication risks in Chinese sufferers Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-03 Ye Shiren, Ye Jiangnan, Ye Xinhua, Ni Xinye
With growing concerns over complications in diabetes sufferers, this study sought to develop an interpretable machine learning model to offer enhanced diagnostic and treatment recommendations. We assessed coronary heart disease, diabetic nephropathy, diabetic retinopathy, and fatty liver disease using logistic regression, decision tree, random forest, and CatBoost algorithms. The SHAP algorithm was
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The COVID-19 pandemic and its impact on the development of gestational diabetes mellitus (GDM) in West Virginia Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-02 Jana Garrow, Isadora Fan, Christa Lilly, Candice Lefeber, Bethany Barone Gibbs, Timothy Lefeber, Collin John, Amna Umer
To examine the rate of gestational diabetes mellitus (GDM) prevalence before and during the COVID-19 pandemic. Analysis revealed that GDM prevalence was significantly higher during the COVID-19 pandemic compared to pre-pandemic (8.59 % vs 7.77 %). The risk of GDM was 12 % higher during the pandemic vs. pre-pandemic (aRR = 1.12, 95 % CI 1.06, 1.19) and the aRD = 0.95 % (95 % CI 0.56 %, 1.33 %) adjusting
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Novel time-saving OGTT sparing HbA1c-HOMA2 based algorithm for the diagnosis of cystic fibrosis-related diabetes Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-02 Fabian Lurquin, Sophie Gohy, Michel P. Hermans, Vanessa Preumont
The diagnosis of cystic fibrosis-related diabetes (CFRD) faces several challenges. We propose a novel screening algorithm to alleviate the burden of cystic fibrosis (CF). Through a retrospective cross-sectional single-centre study, HbA1c and HOMA2 indices were assessed in multiple models as alternative diagnostic tools from OGTT data. We sought to establish specific thresholds for CFRD screening with
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“You can hide it if you want to, you can let it be seen if you want to”: A qualitative study of the lived experiences of Australian adults with type 1 diabetes using the Omnipod DASH® system Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-02 Amber Stocco, Steven Trawley, Yee Wen Kong, Cheng Yi Yuan, Katerina Kiburg, Cecilia Pham, Katrin Brown, Andi Partovi, Kerryn Roem, Natalie Harrison, Spiros Fourlanos, Elif I. Ekinci, David N. O'Neal
Understanding the lived experience of using a tubeless insulin pump and how this differs compared to usual care (tubed insulin pump therapy (IPT) vs multiple daily injections (MDI)). Interviews were conducted after 12-weeks of using the Omnipod DASH Insulin Management System (Insulet, Acton, MA) and analysed using thematic analysis. Fifty-eight adults (35 female; mean age 42;SD 13 years; 35 previous
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Effects of Qidan Tangshen Granule on diabetic kidney disease in patients with type 2 diabetes Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-02 Hua Yang, Shisi Xia, Yilei Cong, Xinyu Yang, Jie Min, Tengfei Wu
This study aimed to conduct a prospective, randomized, controlled clinical trial using, Qidan Tangshen Granule, a traditional Chinese medicine (TCM), as an antioxidant, to treat diabetic kidney disease (DKD) patients. A total of 355 patients were enrolled, and after exclusions, 219 patients were divided into an intervention group (n=109) receiving Qidan Tangshen Granule treatment and a control group
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Simplified gestational diabetes screening with a triaging fasting plasma glucose reduces the burden of oral glucose tolerance tests during pregnancy – A large tertiary comparative cohort study Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-02 Jessica M. Deitch, I-Lynn Lee, Christopher J. Yates, Esha Kathpal, Paul Lawton, Ibrahim Shahid, Peter S. Hamblin, Deepak Dutta, Balasubramanian Krishnamurthy, Joanne M. Said, Cheryl Steele, Glyn R. Teale, Dev Kevat
The study aimed to evaluate the impact of a simplified screeningapproach for gestational diabetes (GDM) compared to conventional screening on OGTT rates, GDM prevalence, and perinatal outcomes. A retrospective comparative cohort study included singleton births from 20 weeks’ gestation. Pregnancies without diagnostic glucose results from 13 weeks’ gestation or incomplete screenings were excluded. Simplified
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Introduction of continuous glucose monitoring (CGM) is a key factor in decreasing HbA1c in war refugee children with type 1 diabetes Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-02 V. Neuman, D. Vavra, L. Drnkova, S. Pruhova, L. Plachy, S. Kolouskova, B. Obermannova, S.A. Amaratunga, P. Konecna, J. Vyzralkova, P. Venhacova, R. Pomahacova, P. Paterova, L. Stichova, J. Skvor, K. Kocourkova, M. Romanova, J. Vosahlo, J. Strnadel, K. Polockova, D. Neumann, M. Slavenko, Z. Sumnik
Our aim was to describe the changes in therapy and diabetes control in Ukrainian war refugee children with diabetes (CwD) during the first year of their stay in Czechia. A total of 124 CwD (62 male, 62 female) were enrolled into this observational study. Anthropometric, laboratory and diabetes management data were acquired at baseline and at 3 months intervals for 12 months. All CwD were offered a
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International Diabetes Federation and Sanofi Global Health Unit collaborate to strengthen diabetes response in 40 countries Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-02
Abstract not available
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Maximum stress hyperglycemia ratio within the first 24 h of admission predicts mortality during and after the acute phase of acute coronary syndrome in patients with and without diabetes: A retrospective cohort study from the MIMIC-IV database Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-02 Hao-ming He, Zhe Wang, Ying-ying Xie, Shu-wen Zheng, Jie Li, Xue-xi Li, Si-qi Jiao, Fu-rong Yang, Yi-hong Sun
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Association between cardiovascular disease risk and incident type 2 diabetes mellitus in individuals with prediabetes: A retrospective cohort study Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-02 Myung Jin Kim, Yun Kyung Cho, Chang Hee Jung, Woo Je Lee
In this study, we aimed to evaluate the impact of overall cardiovascular disease (CVD) risk on the development of incident T2DM in patients with prediabetes. We retrospectively enrolled 5,908 subjects with prediabetes who underwent health check-ups at the Asan Medical Center. CVD risk was estimated using the Framingham Risk Score (FRS). We compared moderate- to high-risk groups with low-risk controls
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Women’s reproductive risk and genetic predisposition in type 2 diabetes: A prospective cohort study Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-01 Xiaojing Liu, Xiaowen Liu, Ninghao Huang, Zeping Yang, Ziyi Zhang, Zhenhuang Zhuang, Ming Jin, Nan Li, Tao Huang
To assess synergistic effects of reproductive factors and gene-reproductive interaction on type 2 diabetes (T2D) risk, also the extent to which the genetic risk of T2D can be affected by reproductive risk. 84,254 women with genetic data and reproductive factors were enrolled between 2006 and 2010 in the UK Biobank. The reproductive risk score (RRS) was conducted based on 17 reproductive items, and
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Incidence of T2DM and the role of baseline glycaemic status as a determinant in a metropolitan population in northern Madrid (Spain) Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-01 V. Iriarte-Campo, C. de Burgos-Lunar, J. Mostaza, C. Lahoz, J. Cárdenas-Valladolid, P. Gómez-Campelo, B. Taulero-Escalera, F.J. San-Andrés-Rebollo, F. Rodriguez-Artalejo, M.A. Salinero-Fort
To estimate the incidence of T2DM and assess the effect of pre-T2DM (isolated impaired fasting glucose [iIFG], isolated impaired glucose tolerance [iIGT] or both) on progress to T2DM in the adult population of Madrid. Population-based cohort comprising 1,219 participants (560 normoglycaemic and 659 preT2DM [418 iIFG, 70 iIGT or 171 IFG-IGT]). T2DM was defined based on fasting plasma glucose or HbA1c
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Association and pathways of baseline and longitudinal hemoglobin A1c with the risk of incident stroke: A nationwide prospective cohort study Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-02-01 Xue Tian, Xue Xia, Yijun Zhang, Qin Xu, Yanxia Luo, Anxin Wang
To investigate the association of baseline and long-term mean hemoglobin A1c (HbA1c) with the risk of stroke. A total of 11,220 participants aged over 45 years and without stroke at baseline were enrolled from the China Health and Retirement Longitudinal Study. Mean HbA1c was calculated as the mean of HbA1c at all previous visits before stroke occurred or the end of follow-up. Multivariable-adjusted
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Patient reported outcomes (PROs) and user experiences of young children with type 1 diabetes using t:slim X2 insulin pump with control-IQ technology Diabetes Res. Clin. Pract. (IF 5.1) Pub Date : 2024-01-24 Korey K. Hood, Aika K. Schneider-Utaka, Zachariah W. Reed, Bruce A. Buckingham, Erin Cobry, Mark D. DeBoer, Laya Ekhlaspour, Melissa Schoelwer, R. Paul Wadwa, John Lum, Craig Kollman, Roy W. Beck, Marc D. Breton
Objective Examine patient-reported outcomes (PROs) after the use of t:slim X2 insulin pump with Control-IQ technology (CIQ) in young children with type 1 diabetes. Methods Children with type 1 diabetes, ages 2 to < 6 years (n = 102), were randomly assigned 2:1 to either CIQ or standard care (SC) with pump or multiple daily injections (MDI) plus continuous glucose monitoring (CGM) for 13 weeks. Both