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  • Correction to: "H" for Heterogeneity in the Algorithm for Type 2 Diabetes Management.
    Curr. Diab. Rep. (IF 3.996) Pub Date : 2020-05-22
    Silvia Pieralice,Simona Zampetti,Ernesto Maddaloni,Raffaella Buzzetti

    The original version of this article unfortunately contained a mistake in the authorgroup section. The authors' given and family names were inadvertently interchanged.

    更新日期:2020-05-22
  • Gastrointestinal Peptides as Therapeutic Targets to Mitigate Obesity and Metabolic Syndrome.
    Curr. Diab. Rep. (IF 3.996) Pub Date : 2020-05-21
    Kleopatra Alexiadou,Tricia M-M Tan

    PURPOSE OF REVIEW Obesity affects over than 600 million adults worldwide resulting in multi-organ complications and major socioeconomic impact. The purpose of this review is to summarise the physiological effects as well as the therapeutic implications of the gut hormones glucagon-like peptide-1 (GLP-1), oxyntomodulin, peptide YY (PYY), and glucose-dependent insulinotropic peptide (GIP) in the treatment

    更新日期:2020-05-21
  • Euglycemic Ketoacidosis.
    Curr. Diab. Rep. (IF 3.996) Pub Date : 2020-05-19
    Benedetta Maria Bonora,Angelo Avogaro,Gian Paolo Fadini

    PURPOSE OF REVIEW Diabetic ketoacidosis is a life-threatening complication of diabetes characterized by hyperglycemia, acidosis, and ketosis. Ketoacidosis may occur with blood glucose level < 200 mg/dl (improperly defined as euglycemic ketoacidosis, euKA) and also in people without diabetes. The absence of marked hyperglycemia can delay diagnosis and treatment, resulting in potential serious adverse

    更新日期:2020-05-19
  • Economic Simulation Modeling in Type 2 Diabetes.
    Curr. Diab. Rep. (IF 3.996) Pub Date : 2020-05-17
    Rahul S Dadwani,Neda Laiteerapong

    PURPOSE OF REVIEW This paper provides an overview of type 2 diabetes economic simulation modeling and reviews current topics of discussion and major challenges in the field. RECENT FINDINGS Important challenges in the field include increasing the generalizability of models and improving transparency in model reporting. To identify and address these issues, modeling groups have organized through the

    更新日期:2020-05-17
  • Updates on Gene Therapy for Diabetic Retinopathy.
    Curr. Diab. Rep. (IF 3.996) Pub Date : 2020-05-16
    Jiang-Hui Wang,Georgina Eloise Roberts,Guei-Sheung Liu

    PURPOSE OF REVIEW Diabetic retinopathy (DR), a leading cause of visual impairment in the developed country, is characterized by vascular lesions and neuronal damage of the retina. Treatment options for this condition are currently limited. The advent of therapy targeting vascular endothelial growth factor (VEGF) demonstrated significant benefits to patients with DR. However, this treatment is limited

    更新日期:2020-05-16
  • Using Person-Reported Outcomes (PROs) to Motivate Young People with Diabetes.
    Curr. Diab. Rep. (IF 3.996) Pub Date : 2020-05-16
    Maartje de Wit,Judith Versloot,Ian Zenlea,Eveline R Goethals

    PURPOSE OF REVIEW This manuscript describes how person-reported outcomes (PROs) can be utilized in care for young people with diabetes in the context of motivation. RECENT FINDINGS The use of person-reported outcome measures (PROMS) in clinical care is feasible and acceptable, and helps focus the clinical encounter on life domains important to the person with diabetes. Results with regard to impact

    更新日期:2020-05-16
  • How Do the Challenges of Emerging Adulthood Inform our Understanding of Diabetes Distress? An Integrative Review.
    Curr. Diab. Rep. (IF 3.996) Pub Date : 2020-04-23
    Katherine Wentzell,Judith A Vessey,Lori M B Laffel

    PURPOSE OF REVIEW Emerging adulthood (ages 18-29) presents many emotional, social, and developmental challenges that can contribute to an increased sense of burden when managing type 1 diabetes (T1D). Diabetes distress (DD) is the concept that captures the emotional burden, frustrations, and worries resulting from living with T1D. This integrative review sets out to examine the impact of developmental

    更新日期:2020-04-23
  • Physiological and Lifestyle Traits of Metabolic Dysfunction in the Absence of Obesity
    Curr. Diab. Rep. (IF 3.996) Pub Date : 2020-03-31
    Hanna Bjørk Klitgaard, Jesper Hoffmann Kilbak, Erica Arhnung Nozawa, Ann V. Seidel, Faidon Magkos

    Purpose of Review Individuals with metabolically unhealthy normal weight (MUNW) have an adverse cardiometabolic risk factor profile in the absence of excess body weight, and increased risk for diabetes and heart disease. We critically review some physiological traits and lifestyle characteristics of the MUNW phenotype. Recent Findings The prevalence of MUNW varies considerably around the world and

    更新日期:2020-04-21
  • "H" for Heterogeneity in the Algorithm for Type 2 Diabetes Management.
    Curr. Diab. Rep. (IF 3.996) Pub Date : 2020-03-20
    Pieralice Silvia,Zampetti Simona,Maddaloni Ernesto,Buzzetti Raffaella

    PURPOSE OF REVIEW Genetic, socioeconomic and clinical features vary considerably among individuals with type 2 diabetes (T2D) influencing disease development, progression and response to therapy. Although a patient-centred approach to pharmacologic therapy of T2D is widely recommended, patients are often treated similarly, irrespective of the differences that may affect therapeutic response. Addressing

    更新日期:2020-04-21
  • Novel Challenges in Aging with Type 1 Diabetes
    Curr. Diab. Rep. (IF 3.996) Pub Date : 2020-03-20
    Jeoffrey A. Bispham, Allyson S. Hughes, Kimberly A. Driscoll, Alicia H. McAuliffe-Fogarty

    Purpose of Review Due to treatment advancements, individuals with type 1 diabetes (T1D) are living longer, presenting a unique understudied population with advanced complex needs. This article is a review of the aging literature in T1D and identifies existing gaps while serving as a call to the research community. Recent Findings Recent studies have identified an association between cognitive impairment

    更新日期:2020-04-21