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Non‐invasive assessment of hepatic steatosis by ultrasound‐derived fat fraction in individuals at high‐risk for metabolic dysfunction‐associated steatotic liver disease Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-03-10 Federica Tavaglione, Valentina Flagiello, Francesca Terracciani, Paolo Gallo, Emma Capparelli, Chiara Spiezia, Antonio De Vincentis, Andrea Palermo, Sara Scriccia, Giovanni Galati, Nicola Napoli, Samuel J. Daniels, Jenny E. Blau, Björn Carlsson, Yeganeh M. Khazrai, Raffaele Antonelli Incalzi, Antonio Picardi, Umberto Vespasiani‐Gentilucci
AimsGiven the increasing number of individuals developing metabolic dysfunction‐associated steatotic liver disease (MASLD) and the low rate of those with progressive liver disease, there is a pressing need to conceive affordable biomarkers to assess MASLD in general population settings. Herein, we aimed to investigate the performance of the ultrasound‐derived fat fraction (UDFF) for hepatic steatosis
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Severe hypoglycemia and hypoglycemia awareness are associated with preclinical atherosclerosis in patients with type 1 diabetes without an estimated high cardiovascular risk Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-03-04 Alex Mesa, Marga Giménez, Verónica Perea, Tonet Serés‐Noriega, Laura Boswell, Jesús Blanco, Camila Milad, Adriana Pané, Enric Esmatjes, Irene Vinagre, Ignacio Conget, Clara Viñals, Antonio J. Amor
AimsTo explore the relationship between severe hypoglycemia (SH) and hypoglycemia awareness with preclinical atherosclerosis in type 1 diabetes (T1D).Materials and MethodsCross‐sectional study in patients with T1D without cardiovascular disease (CVD), and with ≥1 of the following: ≥40 years, diabetic kidney disease, or ≥10 years of T1D duration with another risk factor. CVD risk was estimated with
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Prevalence and risk factors of glomerular hyperfiltration in adults with type 2 diabetes: A population-based study Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-25 Domenico Tricò, Gian Paolo Fadini, Mario Luca Morieri, Riccardo Candido, Olga Eugenia Disoteo, Simona Frontoni, Anna Solini
Glomerular hyperfiltration characterises the earliest stage of diabetic nephropathy and predicts adverse kidney and cardiovascular outcomes. We aimed to assess the prevalence and risk factors of glomerular hyperfiltration in a population-based contemporary cohort of individuals with type 2 diabetes (T2D).
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Insulin requirements during pregnancy in women with type 1 diabetes treated with insulin pump Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-26 Nimrod Dori‐Dayan, Tali Cukierman‐Yaffe, Roni Zemet, Ohad Cohen, Keren Levi, Shali Mazaki‐Tovi, Rakefet Yoeli‐Ullman
IntroductionInsulin requirement in women with Type 1 diabetes (T1DM) changes throughout pregnancy. The aim of this study was to determine the total change in insulin requirements and the effect of gestational weight gain (GWG) and pre‐gestational BMI on insulin requirements during pregnancy in women with T1DM treated with continuous subcutaneous insulin infusion and continuous glucose monitoring.MethodsThis
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Diagnosis and treatment of diabetic foot ulcer complicated with lower extremity vasculopathy: Consensus recommendation from the Chinese Medical Association (CMA), Chinese Medical Doctor Association (CMDA) Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-25 Kejia Wang, Yunchuan Wang, Wenlong Shi, Kuo Shen, Ke Tao, Rui Ling, Yuesheng Huang, Xiaobing Fu, Dahai Hu
Diabetic foot ulcer complicated with lower extremity vasculopathy is highly prevalent, slow healing and have a poor prognosis. The final progression leads to amputation, or may even be life‐threatening, seriously affecting patients' quality of life. The treatment of lower extremity vasculopathy is the focus of clinical practice and is vital to improving the healing process of diabetic foot ulcers.
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Adherence to an energy‐restricted Mediterranean diet is associated with the presence and burden of carotid atherosclerosis in people with type 1 diabetes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-25 Tonet Serés‐Noriega, Clara Viñals, Verónica Perea, Alex Mesa, Laura Boswell, Karla Mariaca, Jesús Blanco, Irene Vinagre, Adriana Pané, Camila Milad, Clara Solà, Enric Esmatjes, Ignacio Conget, Marga Giménez, Antonio J. Amor
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Comparison between sodium‐glucose cotransporter 2 inhibitors and dipeptidyl peptidase 4 inhibitors on the risk of incident cancer in patients with diabetes mellitus: A real‐world evidence study Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-25 Hui‐Lin Sung, Chuan‐Yu Hung, Yu‐Chun Tung, Chih‐Chung Lin, Tung‐Han Tsai, Kuang‐Hua Huang
AimsSodium‐glucose cotransporter 2 inhibitors (SGLT‐2is) have been demonstrated to be associated with cancer cell mechanisms. However, whether they increase the risk of cancer remains unclear. Thus, this study aimed to determine the association between SGLT‐2i use and the incidence of cancer in patients with diabetes mellitus (DM) in Taiwan.Materials and MethodsThis retrospective cohort study was based
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Issue Information Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-22
No abstract is available for this article.
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Clinical care advice for monitoring of islet autoantibody positive individuals with presymptomatic type 1 diabetes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-20 A. Emile J. Hendriks, M. Loredana Marcovecchio, Rachel E. J. Besser, Ezio Bonifacio, Kristina Casteels, Helena Elding Larsson, Gita Gemulla, Markus Lundgren, Olga Kordonouri, Roberto Mallone, Flemming Pociot, Agnieszka Szypowska, Jorma Toppari, Thekla von dem Berge, Anette G. Ziegler, Chantal Mathieu, Peter Achenbach
Type 1 diabetes is an autoimmune disease that involves the development of autoantibodies against pancreatic islet beta-cell antigens, preceding clinical diagnosis by a period of preclinical disease activity. As screening activity to identify autoantibody-positive individuals increases, a rise in presymptomatic type 1 diabetes individuals seeking medical attention is expected. Current guidance on how
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Time-dependent risk of fracture in adults with type 2 diabetes receiving anti-diabetic drug: A one-stage network meta-analysis Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-17 Yanjiao Shen, Qingyang Shi, Xinyu Zou, Wentong Meng, Haoming Tian, Liang Du, Sheyu Li
To assess the time-dependent risk of fracture in adults with type 2 diabetes receiving anti-diabetic drugs.
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Donor fat-to-muscle ratio and kidney transplant outcomes: A proposition of metabolic memory Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-17 Youn Kyung Kee, Juhan Lee, Bo Young Nam, Young Su Joo, Shin-Wook Kang, Kyu Ha Huh, Jung Tak Park
The impact of donor abdominal fat-to-muscle ratio (FMR) on kidney transplant (KT) outcomes was assessed. Given the transient nature of the donor's metabolic environment in transplant recipients, this study investigated the capacity of body composition to induce metabolic memory effects.
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Brain alterations in regions associated with end-organ diabetic microvascular disease in diabetes mellitus: A UK Biobank study Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-16 Jamie Burgess, Christophe de Bezenac, Simon S. Keller, Bernhard Frank, Ioannis N. Petropoulos, Marta Garcia-Finana, Timothy L. Jackson, Varo Kirthi, Daniel J. Cuthbertson, Dinesh Selvarajah, Solomon Tesfaye, Uazman Alam
Diabetes mellitus (DM) is associated with structural grey matter alterations in the brain, including changes in the somatosensory and pain processing regions seen in association with diabetic peripheral neuropathy. In this case-controlled biobank study, we aimed to ascertain differences in grey and white matter anatomy in people with DM compared with non-diabetic controls (NDC).
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Chrononutrition in type 2 diabetes mellitus and obesity: A narrative review Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-16 Ludovica Verde, Tonia Di Lorenzo, Silvia Savastano, Annamaria Colao, Luigi Barrea, Giovanna Muscogiuri
Chrononutrition is a nutritional regimen that follows our biological clock, marked by the changes in metabolism that occur during the day. This regimen includes the distribution of energy, the regularity and frequency of meals, and the importance of these factors for metabolic health. A growing body of animal and human evidence indicates that the timing of food intake throughout the day can have a
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Chrononutrition in cardiometabolic diseases: Current evidence and future perspectives Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-13 Salvatore Carbone, Paolo Pozzilli
Chrononutrition is the field of nutritional science that investigates the relationship between food intake, timing of food intake, and their effects and influence on circadian rhythms and overall health. By aligning eating patterns with body's internal clock, optimisation of metabolic processes, improvements of various aspects of health can be achieved. Cardiovascular (CV) and metabolic diseases remain
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Metabolically healthy obesity, transition from metabolic healthy to unhealthy status, and carotid atherosclerosis Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-13 Qin Huang, Zeyu Liu, Minping Wei, Jie Feng, Qing Huang, Yunhai Liu, Zunjing Liu, XiaoJun Li, Li Yin, Jian Xia
Evidence of the effects of metabolically healthy obesity (MHO) on atherosclerosis is limited; the transition effects of metabolic health and obesity phenotypes have been ignored. We examined the association between metabolic health and the transition to atherosclerosis risk across body mass index (BMI) categories in a community population.
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The impact of sodium-glucose co-transporter-2 inhibitors on dementia and cardiovascular events in diabetic patients with atrial fibrillation Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-10 Yun-Yu Chen, Hao-Chih Chang, Yenn-Jiang Lin, Kuo-Liong Chien, Yu-Cheng Hsieh, Fa-Po Chung, Ching-Heng Lin, Gregory Y. H. Lip, Shih-Ann Chen
The effectiveness of sodium-glucose co-transporter-2 inhibitors (SGLT2i) on incident dementia in patients with diabetes and atrial fibrillation (AF) remains unknown. This study aimed to investigate the association between SGLT2i and the risk of incident dementia in diabetic patients with AF, and to explore the interactions with oral anticoagulants or dipeptidyl peptidase-4 inhibitors (DPP4i).
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Plasma-derived exosomal miRNA profiles associated with type 1 diabetes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-10 Haipeng Pang, Wenqi Fan, Linhua Pi, Xiajie Shi, Zhen Wang, Shuoming Luo, Yang Xiao, Xia Li, Gan Huang, Zhiguo Xie, Zhiguang Zhou
Recently, exosomal miRNAs have been shown to play important roles in multiple diseases, including type 1 diabetes (T1D). To assess the biomarker potential of exosomal miRNAs for T1D, we measured the expression profiles of plasma-derived exosomal miRNAs in T1D and explored their potential functions by bioinformatic analysis.
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Offloading and adherence through technological advancements: Modern approaches for better foot care in diabetes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-08 Sicco A. Bus, Neil D. Reeves, David G. Armstrong, Bijan Najafi
This manuscript aims to provide a review and synthesis of contemporary advancements in footwear, sensor technology for remote monitoring, and digital health, with a focus on improving offloading and measuring and enhancing adherence to offloading in diabetic foot care.
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Association of sodium–glucose cotransporter-2 inhibitors and the risk of retinal vascular occlusion: A real-world retrospective cohort study in Taiwan Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-07 Tzu-Yi Lin, Eugene Yu-Chuan Kang, Shih-Chieh Shao, Edward Chia-Cheng Lai, Nan-Kai Wang, Sunir J. Garg, Kuan-Jen Chen, Je-Ho Kang, Wei-Chi Wu, Chi-Chun Lai, Yih-Shiou Hwang
Sodium–glucose cotransporter-2 inhibitors (SGLT2is) are proposed to alleviate the development of inflammatory eye diseases. However, the association between SGLT2i and retinal vascular occlusion remains unclear. Therefore, this study aims to explore the effects of SGLT2i on the incidence of retinal vascular occlusion.
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Type 1 diabetes: A new vision of the disease based on endotypes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-05 Craig Sinclair Weston, Bernhard O. Boehm, Paolo Pozzilli
Diagnosis and management of type 1 diabetes (T1D) have remained largely unchanged for the last several years. The management of the disease remains primarily focused on its phenotypical presentation and less on endotypes, namely the specific biological mechanisms behind the development of the disease. Furthermore, the treatment of T1D is essentially universal and indiscriminate—with patients administering
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Muscle-to-fat ratio in children and adolescents with type 1 diabetes in predicting glycaemic control and partial clinical remission Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-05 Shay Averbuch, Michal Yackobovitch-Gavan, Asaf Ben Simon, Hagar Interator, Adar Lopez, Ophir Borger, Irina Laurian, Anna Dorfman, Efrat Chorna, Asaf Oren, Ori Eyal, Avivit Brener, Yael Lebenthal
Advances in treatment could mitigate the expected adverse changes in the body composition of children and adolescents with type 1 diabetes (T1D).
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The transiency of metabolically healthy obesity: Metabolic decline and atherosclerotic risk Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-02-05 Saeid Mirzai, Ian J. Neeland, Carl J. Lavie
1 INTRODUCTION The concept of metabolically healthy obesity (MHO)—obesity in the absence of metabolic abnormalities such as hypertension, dyslipidemia, and hyperglycemia—has sparked intense debate.1 Up to 40% of people with obesity exhibit an MHO phenotype, seemingly escaping obesity's expected cardiometabolic sequelae.2 But is this a real phenomenon with a persistent favourable prognosis, or does
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Chronicles of progress: Celebrating 40 years of scientific excellence in diabetes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-01-31 Paolo Pozzilli
The 40th anniversary of Diabetes Metabolism Research and Reviews (DMRR) marks a significant milestone in the field, reflecting four decades of continuous dedication to advancing our understanding of diabetes and related metabolic disorders. Over the years, the journal has been a pivotal platform for disseminating groundbreaking research and review articles that have shaped the landscape of diabetes
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Issue Information Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-01-27
No abstract is available for this article.
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Assessment of six surrogate insulin resistance indexes for predicting cardiometabolic multimorbidity incidence in Chinese middle-aged and older populations: Insights from the China health and retirement longitudinal study Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-01-24 Danrui Xiao, Honglin Sun, Long Chen, Xiang Li, Huanhuan Huo, Guo Zhou, Min Zhang, Ben He
Insulin resistance (IR) is associated with cardiometabolic multimorbidity (CMM). We aimed to explore the predictive value of six surrogate IR indexes—Chinese visceral adiposity index (CVAI), lipid accumulation product (LAP), triglyceride-glucose (TyG), atherogenic index of plasma (AIP), TyG-body mass index (TyGBMI), and TyG-waist circumference (TyGwaist)—to establish the CMM incidence in Chinese middle-aged
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The role of autophagy in insulin resistance and glucolipid metabolism and potential use of autophagy modulating natural products in the treatment of type 2 diabetes mellitus Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-01-24 Xiaoxue Yang, Wenwen Ding, Ziyi Chen, Kaiyi Lai, Ying Liu
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Issue Information Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-01-07
No abstract is available for this article.
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Type 2 diabetes metabolomics score and risk of progression to type 2 diabetes among women with a history of gestational diabetes mellitus Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-01-07 Deirdre K. Tobias, Rikuta Hamaya, Clary B. Clish, Liming Liang, Amy Deik, Courtney Dennis, Kevin Bullock, Cuilin Zhang, Frank B. Hu, JoAnn E. Manson
Several metabolites are individually related to incident type 2 diabetes (T2D) risk. We prospectively evaluated a novel T2D-metabolite pattern with a risk of progression to T2D among high-risk women with a history of gestational diabetes mellitus (GDM).
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Obesogenic environments as major determinants of a disease: It is time to re-shape our cities Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-01-07 Ludovica Verde, Luigi Barrea, Jacqueline Bowman-Busato, Volkan Demirhan Yumuk, Annamaria Colao, Giovanna Muscogiuri
Obesity rates are increasing in almost all high- and low-income countries, and population-based approaches are necessary to reverse this trend. The current global efforts are focused on identifying the root causes of obesity and developing effective methods for early diagnosis, screening, treatment, and long-term management, both at an individual and health system level. However, there is a relative
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Poor self-rated health is associated with faster cognitive decline and greater small vessel disease in older adults with type 2 diabetes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-01-07 Nadia Ramsingh, Hung-Mo Lin, Yuxia Ouyang, Ramit Ravona-Springer, Abigail Livny, Laili Soleimani, Barbara B. Bendlin, Mery Ben Meir, Anthony Heymann, Mary Sano, Joseph Azuri, Michal Schnaider Beeri
Self-rated health (SRH) is a predictor for poor health outcomes and cognition. Older adults with type 2 diabetes mellitus (T2D) have multi-morbidity and greater cognitive impairment. In the present study we investigated the association of SRH with cognitive decline and brain pathology in older adults with T2D.
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Chrono-nutrition for hypertension Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2024-01-07 Natalie J. Bohmke, Dave L. Dixon, Danielle L. Kirkman
Despite the advancement in blood pressure (BP) lowering medications, uncontrolled hypertension persists, underscoring a stagnation of effective clinical strategies. Novel and effective lifestyle therapies are needed to prevent and manage hypertension to mitigate future progression to cardiovascular and chronic kidney diseases. Chrono-nutrition, aligning the timing of eating with environmental cues
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Cardio-renal-metabolic disease in primary care setting Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-12-19 Mahmoud Ibrahim, Ebtesam M. Ba-Essa, Jason Baker, Avivit Cahn, Antonio Ceriello, Francesco Cosentino, Melanie J. Davies, Robert H. Eckel, Luc Van Gaal, Peter Gaede, Yehuda Handelsman, Samuel Klein, Richard David Leslie, Paolo Pozzilli, Stefano Del Prato, Francesco Prattichizzo, Oliver Schnell, Petar M. Seferovic, Eberhard Standl, Abraham Thomas, Jaakko Tuomilehto, Paul Valensi, Guillermo E. Umpierrez
In the primary care setting providers have more tools available than ever before to impact positively obesity, diabetes, and their complications, such as renal and cardiac diseases. It is important to recognise what is available for treatment taking into account diabetes heterogeneity. For those who develop type 2 diabetes (T2DM), effective treatments are available that for the first time have shown
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Interactive effects of gestational diabetes and high pre-pregnancy body mass index on adverse growth patterns of offspring Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-12-18 Weihan Cao, Ninghua Li, Rui Zhang, Weiqin Li, Ming Gao, Hui Wang, Leishen Wang, Yijuan Qiao, Jing Li, Zhijie Yu, Gang Hu, Junhong Leng, Xilin Yang
To examine the independent and interactive effects of maternal gestational diabetes mellitus (GDM) and high pre-pregnancy body mass index (BMI) on the risk of offspring adverse growth patterns.
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Does a prior diagnosis of infectious disease confer an increased risk of latent autoimmune diabetes in adults? Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-12-16 Jessica Edstorp, Marios Rossides, Emma Ahlqvist, Bahareh Rasouli, Tiinamaija Tuomi, Sofia Carlsson
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Letter: Statin use in patients with type 2 diabetes has lower risk of hip fractures Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-12-13 Shih-Wei Huang, I.-Ming Jou, Renin Chang
We read with great interest the article ‘Statin use in patients with type 2 diabetes has lower risk of hip fractures: A Taiwan national population-based study’ by Tien-Ching Lee et al.1 They described that statin use was a significant and independent protective factor of hip fractures with an adjusted HR of 0.69. In addition, they noted a significant dose-response relationship between statin use and
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Longitudinal cardiovascular health measured by life's essential 8 metrics with incident diabetes: A 13-year prospective cohort study Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-12-08 Xue Tian, Shuohua Chen, Qin Xu, Xue Xia, Yijun Zhang, Xiaoli Zhang, Penglian Wang, Shouling Wu, Anxin Wang
To investigate the associations of baseline and longitudinal cardiovascular health (CVH) measured by ‘Life's Essential 8’ (LE8) metrics with the risk of diabetes in Chinese people with normoglycaemia or prediabetes.
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Charcot neuroarthropathy in persons with diabetes: It's time for a paradigm shift in our thinking Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-12-08 Dane K. Wukich, Robert G. Frykberg, Venu Kavarthapu
The aim of this paper is to review the recent literature regarding the epidemiology and surgical management of Charcot neuro-osteoarthropathy (CNO). We propose that a fundamental change in the approach and assumptions regarding the historical treatment of active CNO should be considered. Although the true incidence and prevalence of CNO in the US population with diabetes are not known, we estimated
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Endostatin, soluble tumour necrosis factor receptor 1 and soluble tumour necrosis factor receptor 2 cannot predict new onset of microalbuminuria in patients with type 2 diabetes Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-12-04 Florian G. Scurt, Jan Menne, Sabine Brandt, Anja Bernhardt, Peter R. Mertens, Hermann Haller, Christos Chatzikyrkou
Inflammation and angiogenesis play an important role in the development of early diabetic kidney disease. We investigated the association of soluble Tumour Necrosis Factor Receptor 1 (sTNF-R1), sTNF-R2 and endostatin with new onset microalbuminuria in normoalbuminuric patients with diabetes mellitus type 2.
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Incidence of type 1 diabetes mellitus in children and adolescents under 20 years of age across 55 countries from 2000 to 2022: A systematic review with meta-analysis Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-12-01 Ignacio Hormazábal-Aguayo, Yasmin Ezzatvar, Nidia Huerta-Uribe, Robinson Ramírez-Vélez, Mikel Izquierdo, Antonio García-Hermoso
The aim of this study was to determine the global incidence of type 1 diabetes mellitus (T1DM) in children and adolescents under 20 years of age from 2000 to 2022.
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The quest for wellness: How to optimise self-care strategies for diabetic foot management? Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-12-01 Frans Pouwer, Byron Perrin, Andy Lavender, Bijan Najafi, Khalida Ismail, Loretta Vileikyte
Diabetic foot ulceration (DFU) is common and highly recurrent, negatively impacting the individuals' quality of life. The 2023 guidelines of the International Working Group on the Diabetic Foot emphasise that adherence to foot self-care recommendations is one of the most important factors in DFU prevention. These guidelines also briefly mention that depression and other psychosocial problems can hamper
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Postbariatric surgery hypoglycemia: Nutritional, pharmacological and surgical perspectives Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-11-28 Giovanni Rossini, Renata Risi, Lavinia Monte, Biagio Sancetta, Maria Quadrini, Massimiliano Ugoccioni, Davide Masi, Rebecca Rossetti, Rossella D’Alessio, Rossella Mazzilli, Giuseppe Defeudis, Carla Lubrano, Lucio Gnessi, Mikiko Watanabe, Silvia Manfrini, Dario Tuccinardi
Post-bariatric hypoglycaemia (PBH) is a metabolic complication of bariatric surgery (BS), consisting of low post-prandial glucose levels in patients having undergone bariatric procedures. While BS is currently the most effective and relatively safe treatment for obesity and its complications, the development of PBH can significantly impact patients' quality of life and mental health. The diagnosis
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Efficacy and safety of fixed-ratio combination insulin degludec/liraglutide in type 2 diabetes: A systematic review and meta-analysis of randomised controlled trials Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-11-27 Rui Wang, Shuoming Luo, Zilin Xiao, Zhiguang Zhou
The efficacy and safety of fixed-ratio combination insulin degludec/liraglutide (IDegLira) for type 2 diabetes (T2DM) were extensively investigated by the global DUAL trials. However, the evidence on its efficacy and safety in T2DM has not been systematically reviewed.
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A new declaration for feet's sake: Halving the global diabetic foot disease burden from 2% to 1% with next generation care Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-11-24 Peter A. Lazzarini, Katherine M. Raspovic, Marco Meloni, Jaap J. van Netten
The 1989 Saint Vincent Declaration established a goal of halving global diabetes-related amputation rates. A generation later, this goal has been achieved for major but not minor amputations. However, diabetic foot disease (DFD) is not only a leading cause of global amputation but also of hospitalisation, poor quality of life (QoL) and disability burdens. In this paper, we review latest estimates on
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Letter: Statin use in patients with type 2 diabetes has lower risk of hip fractures: A Taiwan national population-based study Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-11-21 Ming-I Wei, Wen-Bin Yeh, Renin Chang
Editors, We read with great interest the research carried out by Lee et al. on the association between statin use and the risk of hip fracture in patients with type 2 diabetes mellitus (T2DM).1 They pointed out a decreased likelihood of hip fracture among statin-using T2DM patients with an adjusted hazard ratio of 0.69. This research surely marked a milestone in terms of the long-disputed relationship
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Worldwide burden and trends of diabetes among people aged 70 years and older, 1990–2019: A systematic analysis for the Global Burden of Disease Study 2019 Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-11-09 Shimin Jiang, Tianyu Yu, Dingxin Di, Ying Wang, Wenge Li
Diabetes places a significant burden on personal and public health. However, a comprehensive assessment of the burden of diabetes in older adults is lacking. We aimed to estimate the global burden of diabetes and explore trends for the population aged ≥70 from 1990 to 2019.
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Effectiveness of educational interventions for diabetes-related foot disease: A systematic review and meta-analysis Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-11-05 Aaron Drovandi, Leonard Seng, Jonathan Golledge
This systematic review and meta-analysis pooled evidence from randomised controlled trials (RCTs) on the effectiveness of educational programs for people with or at risk of diabetes-related foot disease (DFD). A systematic search identified RCTs evaluating the effectiveness of educational programs in preventing or managing DFD. The primary outcome was risk of developing a foot ulcer. Secondary outcomes
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Issue Information Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-11-02
No abstract is available for this article.
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One third of cases of new-onset diabetic ketosis in adults are associated with ketosis-prone type 2 diabetes—A systematic review and meta-analysis Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-10-27 Adrienn Kovacs, Stefania Bunduc, Daniel S. Veres, Daniel Palinkas, Endre B. Gagyi, Peter J. Hegyi, Balint Eross, Emese Mihaly, Peter Hegyi, Nora Hosszufalusi
Ketosis-prone type 2 diabetes was defined by the World Health Organization in 2019. According to the literature, the diagnosis is based on the presence of ketosis, islet autoantibody negativity and preserved insulin secretion. Our meta-analysis assessed the prevalence and clinical characteristics of ketosis-prone type 2 diabetes among patients hospitalised with diabetic ketoacidosis (DKA) or ketosis
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Diabetes Study of Children of Diverse Ethnicity and Race: Study design Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-10-27 Maria J. Redondo, Kylie K. Harrall, Deborah H. Glueck, Mustafa Tosur, Serife Uysal, Andrew Muir, Elizabeth G. Atkinson, Melanie R. Shapiro, Liping Yu, William E. Winter, Michael Weedon, Todd M. Brusko, Richard Oram, Kendra Vehik, William Hagopian, Mark A. Atkinson, Dana Dabelea
Determining diabetes type in children has become increasingly difficult due to an overlap in typical characteristics between type 1 diabetes (T1D) and type 2 diabetes (T2D). The Diabetes Study in Children of Diverse Ethnicity and Race (DISCOVER) programme is a National Institutes of Health (NIH)-supported multicenter, prospective, observational study that enrols children and adolescents with non-secondary
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Preconception episodes of severe hypoglycemia and risk of adverse pregnancy outcomes in pregnant women with type 1 diabetes mellitus Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-10-24 Yixin Gong, Sihui Luo, Jie Shi, Tian Wei, Jing Wang, Yujie Liu, Jinhua Yan, Daizhi Yang, Ling Li, Zilin Sun, Xueying Zheng, Jianping Weng
To explore the relationship between preconception severe hypoglycemia (PSH) and pregnancy outcomes in pregnancies complicated with type 1 diabetes mellitus (T1DM).
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Response to Letter to the Editor Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-10-20 Tien-Ching Lee, Pei-Shan Ho
We thank Dr. Wei etc. for their interest and knowledgeable comments on our study. One concern was the immortal time bias. After we used ‘landmark analysis’ to justify it,1-3 174,252 patients were identified as statin and non-statin users. Statin use after type 2 diabetes mellitus (T2DM) diagnosis was associated with a decreased hip fracture (HFx) risk with an adjusted HR (aHR) of 0.81 (p < 0.001).
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Sodium-glucose co-transporter-2 inhibitors and the risk of venous thromboembolism: A nationwide population-based study and meta-analysis Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-10-20 Hou-Ren Tsai, Yu-Jie Lin, Jih-I Yeh, Yu-Chi Huang, Peter Pin-Sung Liu, Carol Chiung-Hui Peng, Jin-Yi Hsu, Yuan-Chieh Lee, Ching-Hui Loh, Shu-Man Lin, Huei-Kai Huang
Sodium-glucose cotransporter-2 inhibitors (SGLT-2i) have off-target effects on haemoconcentration and anti-inflammation. The impact of SGLT-2i on the risk of venous thromboembolism (VTE) in patients with diabetes mellitus (DM) remains unclear. This study aimed to evaluate the risk of newly diagnosed VTE in patients with DM using SGLT-2i in comparison to dipeptidyl peptidase-4 inhibitors (DPP-4i) or
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Assessment and management of diabetes-related foot infection according to the new International Working Group on the Diabetic Foot guidelines 2023—Multidisciplinary grand rounds Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-10-19 Kay Hon, Frank Nobels, Éric Senneville, Ilker Uckay, Mario Maas, Robert Fitridge
Diabetes-related foot disease is a serious and common complication for people with diabetes mellitus. The gold standard care for a person with diabetes-related foot disease is the involvement of a multidisciplinary foot team engaged in evidence-based care. To date, there are seven International Working Group on the Diabetic Foot (IWGDF) guidelines published to assist healthcare providers in managing
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Validation in type 2 diabetes of a metabolomic signature of all-cause mortality Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-10-15 Massimiliano Copetti, Marco Giorgio Baroni, Raffaella Buzzetti, Maria Gisella Cavallo, Efiso Cossu, Paola D’Angelo, Salvatore De Cosmo, Frida Leonetti, Susanna Morano, Lelio Morviducci, Nicola Napoli, Sabrina Prudente, Giuseppe Pugliese, Antonio Fernando Savino, Vincenzo Trischitta
Mortality in type 2 diabetes is twice that of the normoglycemic population. Unravelling biomarkers that identify high-risk patients for referral to the most aggressive and costly prevention strategies is needed.
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Non-coding RNAs in diabetic foot ulcer- a focus on infected wounds Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-10-15 Boquan Qin, Qi Peng, Hongxian Dong, Lei Lei, Shizhou Wu
Diabetes mellitus is associated with a wide range of neuropathies, vasculopathies, and immunopathies, resulting in many complications. More than 30% of diabetic patients risk developing diabetic foot ulcers (DFUs). Non-coding RNAs (ncRNAs), including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), play essential roles in various biological functions in the hyperglycaemic
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Simple proxies of insulin resistance identify obese metabolic dysfunction-associated fatty liver disease subjects with advanced liver disease Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-10-15 Giovanni Petralli, Antonio Salvati, Domenico Tricò, Gabriele Ricco, Piero Colombatto, Maurizia Rossana Brunetto, Anna Solini
Insulin resistance (IR) plays a pivotal role in the pathogenesis of Metabolic dysfunction-Associated Fatty Liver Disease (MAFLD), which can progress to liver fibrosis. We examined the relationship of different IR scores with markers of MAFLD severity in obese individuals.
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Chrononutrition in the context of Ramadan: Potential implications Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-10-13 Tomader Ali, Nader Lessan
Every year, healthy adult Muslims practice dawn to sunset fasting for a whole lunar month. No food or fluid is allowed for the fasting time window. After sunset, eating is allowed. The dramatic change in the timing of meals is accompanied by changes in sleeping hours and thus alterations in circadian rhythms. Hormonal mechanisms mainly determined by the latter also change. These include shifts in cortisol
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Mitochondrial damage-associated molecular patterns: A new insight into metabolic inflammation in type 2 diabetes mellitus Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-10-12 Yan Wang, Jingwu Wang, Si-Yu Tao, Zhengting Liang, Rong xie, Nan-nan Liu, Ruxue Deng, Yuelin Zhang, Deqiang Deng, Guangjian Jiang
The pathogenesis of diabetes is accompanied by increased levels of inflammatory factors, also known as “metabolic inflammation”, which runs through the whole process of the occurrence and development of the disease. Mitochondria, as the key site of glucose and lipid metabolism, is often accompanied by mitochondrial function damage in type 2 diabetes mellitus (T2DM). Damaged mitochondria release pro-inflammatory
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Cover Image Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-10-09 Ping Ling, Daizhi Yang, Chaofan Wang, Xueying Zheng, Sihui Luo, Xubin Yang, Hongrong Deng, Wen Xu, Jinhua Yan, Jianping Weng
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Issue Information Diabetes Metab. Res. Rev. (IF 8.0) Pub Date : 2023-10-09
No abstract is available for this article.