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An exploratory analysis of the cost‐effectiveness of insulin glargine 300 units/mL versus insulin glargine 100 units/mL over a lifetime horizon using the BRAVO diabetes model Diabet. Med. (IF 3.5) Pub Date : 2024-03-12 Hui Shao, Lizheng Shi, Vivian Fonseca, Abdul Jabbar Omar Alsaleh, Jasvinder Gill, Charlie Nicholls
BackgroundThis analysis assessed the cost‐effectiveness of insulin glargine 300 units/mL (Gla‐300) versus insulin glargine 100 units/mL (Gla‐100) in insulin‐naïve adults with type 2 diabetes (T2D) inadequately controlled with oral antidiabetic drugs (OADs).MethodsCosts and outcomes for Gla‐300 versus Gla‐100 from a US healthcare payer perspective were assessed using the BRAVO diabetes model. Baseline
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Postpartum oral glucose tolerance test in women with prior gestational diabetes. Does breastfeeding affect the results? Analysis of hormonal profiles Diabet. Med. (IF 3.5) Pub Date : 2024-03-07 Gabriela Monroy, Cristina Fernández, Laura Altimira, Uxia Barba, Rosa Corcoy
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Profiles of disordered eating behaviour in type 1 diabetes using the DEPS‐R and behaviour and glycaemic outcomes in a real‐life setting Diabet. Med. (IF 3.5) Pub Date : 2024-03-07 Rhonda M. Merwin, Natalia O. Dmitrieva, Ashley A. Moskovich, Jennifer L. Warnick, Ann E. Goebel‐Fabbri, Lisa Swartz Topor, Katherine E. Darling
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Psychometric properties of the Diabetes Eating Problem Survey–Revised among Dutch adults with type 1 diabetes and implications for clinical use Diabet. Med. (IF 3.5) Pub Date : 2024-03-05 Jiska Embaye, Mareille Hennekes, Frank Snoek, Maartje de Wit
AimsDisordered eating behaviour (DEB) in people with type 1 diabetes (T1D) can be screened with the Diabetes Eating Problem Survey–Revised (DEPS‐R). This study aimed to investigate the psychometric properties of the DEPS‐R among Dutch adults with T1D and to explore the individual items alongside the standard cut‐off score of ≥20 for clinical use.MethodsThe construct validity of the DEPS‐R was assessed
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Cost-effectiveness of a Novel Hypoglycaemia Programme: The ‘HARPdoc vs BGAT’ RCT Diabet. Med. (IF 3.5) Pub Date : 2024-02-29 Andrew Healey, Tayana Soukup, Nick Sevdalis, Ioannis Bakolis, Samantha Cross, Simon R. Heller, Augustin Brooks, Dulmini Kariyawasam, Elena Toschi, Linda Gonder-Frederick, Marietta Stadler, Helen Rogers, Kimberley Goldsmith, Pratik Choudhary, Nicole de Zoysa, Stephanie A. Amiel
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Design, recruitment and baseline characteristics of the LENS trial Diabet. Med. (IF 3.5) Pub Date : 2024-02-22
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Roles and competencies of the clinical psychologist in adult diabetes care—A consensus report Diabet. Med. (IF 3.5) Pub Date : 2024-02-22 Frank J. Snoek, Maria Teresa Anarte‐Ortiz, Therese Anderbro, Katarzyna Cyranka, Christel Hendrieckx, Norbert Hermanns, Liliana Indelicato, Brian E. McGuire, Andreia Mocan, Giesje Nefs, William H. Polonsky, Rose Stewart, Michael Vallis
AimsPsychological care is recognised as an integral part of quality diabetes care. We set out to describe the roles and competencies of the clinical psychologist as a member of the multidisciplinary adult diabetes care team, focused on secondary care.MethodsThe authors are clinically experienced psychologists involved in adult diabetes care, from Australia, Europe and North America, and active members
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Satisfaction with continuous glucose monitoring is associated with quality of life in young people with type 1 diabetes regardless of metabolic control and treatment type Diabet. Med. (IF 3.5) Pub Date : 2024-02-22 Roberto Franceschi, Riccardo Pertile, Marco Marigliano, Enza Mozzillo, Claudio Maffeis, Elisa Morotti, Francesca Di Candia, Ludovica Fedi, Dario Iafusco, Angela Zanfardino, Vittoria Cauvin, Giulio Maltoni, Stefano Zucchini, Valentino Cherubini, Valentina Tiberi, Nicola Minuto, Marta Bassi, Ivana Rabbone, Silvia Savastio, Davide Tinti, Gianluca Tornese, Riccardo Schiaffini, Stefano Passanisi, Fortunato
AimsWhile continuous glucose monitoring (CGM) and associated technologies have positive effects on metabolic control in young people with type 1 diabetes (T1D), less is known about their impact on quality of life (QoL). Here, we quantified CGM satisfaction and QoL in young people with T1D and their parents/caregivers to establish (i) the relationship between QoL and CGM satisfaction and (ii) the impact
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A cognitive behavioural model of the bidirectional relationship between disordered eating and diabetes self care in adult men with Type 1 diabetes mellitus Diabet. Med. (IF 3.5) Pub Date : 2024-02-21 Amy Harrison, Emmanouela Konstantara, Natalie Zaremba, Jennie Brown, Jacqueline Allan, Divina Pillay, David Hopkins, Janet Treasure, Khalida Ismail, Marietta Stadler
AimsThis qualitative study aimed to develop the first cognitive behavioural (CBT) model outlining the development and maintenance of disordered eating in adult men living with Type 1 diabetes to improve on previous theoretical models of Type 1 diabetes and disordered eating and to draw comparisons to women with Type 1 diabetes and disordered eating.MethodsTwenty‐seven men (n = 16 with Type 1 diabetes
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Participants' experiences of attending a structured education course (DAFNEplus) informed by behavioural science Diabet. Med. (IF 3.5) Pub Date : 2024-02-15 Julia Lawton, Paul M. Chadwick, Nicole de Zoysa, Stephanie Stanton-Fay, Simon R. Heller, David Rankin
As part of a broader process evaluation, we explored participants' experiences of, and engagement with, the DAFNEplus programme's group-based structured education course. This course, which was informed by behavioural science, provided participants with education and instruction to use flexible intensive insulin therapy (FIIT) together with techniques to identify and address unhelpful cognitive and
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The use of dietary supplements, and the association between supplemental vitamin D and glycaemic control in adult individuals with type 1 diabetes Diabet. Med. (IF 3.5) Pub Date : 2024-02-14 Aila J. Ahola, Valma Harjutsalo, Per-Henrik Groop
To assess the dietary supplement use in adult individuals with type 1 diabetes, and to study the association between vitamin D supplementation and glycaemic control in an observational cross-sectional study.
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The impact of stigma on the management of type 1 diabetes: A systematic review Diabet. Med. (IF 3.5) Pub Date : 2024-02-15 Ronda Embick, Mike Jackson, Rose Stewart
To systematically review the literature investigating the links between stigma and the management of type 1 diabetes.
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A qualitative study of the perceptions and experiences of participants and healthcare professionals in the DiRECT-Australia type 2 diabetes remission service Diabet. Med. (IF 3.5) Pub Date : 2024-02-04 Ritesh Chimoriya, Freya MacMillan, Michael Lean, David Simmons, Milan K. Piya
The UK Diabetes Remission Clinical Trial (DiRECT) study was replicated in an Australian primary care setting. This qualitative study aimed to explore and understand the perceptions and experiences of both participants and healthcare professionals (HCPs) involved in the DiRECT-Australia Type 2 Diabetes Remission Service.
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An estimate of the need for continuous glucose monitoring in type 2 diabetes with intensive insulin treatment in secondary healthcare Diabet. Med. (IF 3.5) Pub Date : 2024-02-02 Christian Trolle, Mia Christensen, Klavs Würgler Hansen
To estimate the proportion of persons with type 2 diabetes (T2DM) receiving intensive insulin treatment in the secondary healthcare who could be candidates for continuous glucose monitoring (CGM), based on different HbA1c criteria. For comparison, the results are also presented as proportion of persons with type 1 diabetes (T1DM) in the same region.
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An unusual finding on routine diabetes retinal screening Diabet. Med. (IF 3.5) Pub Date : 2024-02-01 Tahseen A. Chowdhury, John V. Anderson
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest.
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Beyond the individual: Socio-ecological factors impacting activity after gestational diabetes mellitus Diabet. Med. (IF 3.5) Pub Date : 2024-01-30 Elysa Ioannou, Helen Humphreys, Catherine Homer, Alison Purvis
The risk of Type 2 Diabetes is 10 times higher after a pregnancy with Gestational Diabetes. Physical activity can independently reduce this risk, yet engagement with physical activity remains low after Gestational Diabetes. Therefore, the present study aimed to explore the barriers and facilitators to the uptake of physical activity after Gestational Diabetes in the United Kingdom, using a socio-ecological
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A novel approach to accurately measuring the burden of hospitalisations for cardiovascular disease in people with diabetes: A pilot study Diabet. Med. (IF 3.5) Pub Date : 2024-01-27 Quan Huynh, John Burgess, Kate Flentje, Neville Tan, Riley Batchelor, Thomas H. Marwick, Jonathan E. Shaw
To determine the reliability of hospital discharge codes for heart failure (HF), acute myocardial infarction (AMI) and stroke compared with adjudicated diagnosis, and to pilot a scalable approach to adjudicate records on a population-based sample.
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Impact of personalized diabetes care on distress and treatment satisfaction in people with breast cancer Diabet. Med. (IF 3.5) Pub Date : 2024-01-30 Julia C. Harrod, Yee-Ming M. Cheung, Lauren Buckley, Grace E. Cromwell, Kristen M. Fowler, Melissa E. Hughes, Nancy U. Lin, Sara M. Tolaney, Le Min, Marie E. McDonnell
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A novel approach to understanding and assessing the emotional side of type 1 diabetes: The Type 1-Diabetes Distress Assessment System Diabet. Med. (IF 3.5) Pub Date : 2024-01-20 Lawrence Fisher, William Polonsky, Diana Naranjo, Lisa Strycker, Danielle Hessler
To describe the development of a novel, conceptually sound instrument with contemporary content for assessing diabetes distress (DD) among adults with type 1 diabetes.
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A core outcome set for trials evaluating self-management interventions in people with severe mental illness and coexisting type 2 diabetes Diabet. Med. (IF 3.5) Pub Date : 2024-01-18 Claire Carswell, Jo Taylor, Richard I. G. Holt, Jennifer V. E. Brown, Ramzi Ajjan, Jan R. Böhnke, Tim Doran, Ian Kellar, David Shiers, Judy Wright, Najma Siddiqi
People with severe mental illness (SMI), such as schizophrenia, have higher rates of type 2 diabetes and worse outcomes, compared to those without SMI and it is not known whether diabetes self-management interventions are effective for people who have both conditions. Research in this area has been impeded by a lack of consensus on which outcomes to prioritise in people with co-existing SMI and diabetes
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Cover Image Diabet. Med. (IF 3.5) Pub Date : 2024-01-15 Adam K. Stanley, Kirsty Duncan, Debbie Anderson, Lora Irvine, Andrew Sutherland, Shareen Forbes, John Casey
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Relative poverty is associated with increased risk of diabetic ketoacidosis at onset of type 1 diabetes in children. A Swedish national population-based study in 2014–2019 Diabet. Med. (IF 3.5) Pub Date : 2024-01-11 Johan H. Wersäll, Jan Ekelund, Karin Åkesson, Ragnar Hanas, Peter Adolfsson, Sven-Erik Ricksten, Gun Forsander
The aim of the study was to estimate the effect of household relative poverty on the risk of diabetic ketoacidosis at diagnosis of children with type 1 diabetes using an international standard measurement of relative poverty.
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Preterm delivery and maternal obesity remain common complications in pregnancies with type 1 diabetes—A nationwide study in Sweden Diabet. Med. (IF 3.5) Pub Date : 2024-01-11 Sven Sandin, Hans Järnbert-Pettersson, Martina Persson
A primary goal of obstetric care of women with type 1 diabetes (T1D) is to reduce the risks of preterm birth (PTB). Besides hyperglycaemia, maternal obesity is an important risk factor for PTB in T1D. However, it's unclear if public health efforts decreased risks of maternal obesity and PTB in pregnancies with T1D. We examined time-trends over the last 20 years in the distribution of gestational ages
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Mouse islet-derived stellate cells are similar to, but distinct from, mesenchymal stromal cells and influence the beta cell function Diabet. Med. (IF 3.5) Pub Date : 2024-01-07 Wei Xu, Yunting Zhou, Tianyuan Wang, Chengming Ni, Chunlei Wang, Rui Li, Xuekui Liu, Jun Liang, Tzu-wen Hong, Bo Liu, Aileen J. F. King, Shanta J. Persaud, Zilin Sun, Peter M. Jones
Evidence is accumulating of the therapeutic benefits of mesenchymal stromal cells (MSCs) in diabetes-related conditions. We have identified a novel population of stromal cells within islets of Langerhans – islet stellate cells (ISCs) – which have a similar morphology to MSCs. In this study we characterize mouse ISCs and compare their morphology and function to MSCs to determine whether ISCs may also
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Comparing the glycaemic outcomes between real-time continuous glucose monitoring (rt-CGM) and intermittently scanned continuous glucose monitoring (isCGM) among adults and children with type 1 diabetes: A systematic review and meta-analysis of randomized controlled trials Diabet. Med. (IF 3.5) Pub Date : 2024-01-10 Yongwen Zhou, Divesh Sardana, Sarahmarie Kuroko, Jillian J. Haszard, Martin I. de Block, Jianping Weng, Craig Jefferies, Benjamin John Wheeler
To conduct a systematic review and meta-analysis of randomized controlled trials (RCTs) comparing the effectiveness of real-time continuous glucose monitoring (rtCGM) versus intermittently scanned continuous glucose monitoring (isCGM) on key glycaemic metrics (co-primary outcomes HbA1c and time-in-range [TIR] 70–180 mg/dL, 3.9–10.0 mmol/L) among people with type 1 diabetes (T1D).
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Protocol for the STEADY intervention for type 1 diabetes and disordered eating: Safe management of people with Type 1 diabetes and EAting Disorders studY Diabet. Med. (IF 3.5) Pub Date : 2024-01-08 Natalie Zaremba, Amy Harrison, Jennie Brown, Jacqueline Allan, Divina Pillay, Janet Treasure, Salma Ayis, David Hopkins, Khalida Ismail, Marietta Stadler
This paper describes the protocol to test the feasibility of the Safe management of people with Type 1 diabetes and EAting Disorders studY (STEADY) intervention. STEADY is a novel complex intervention for people with type 1 diabetes and disordered eating (T1DE) of mild to moderate severity. The STEADY intervention integrates cognitive behavioural therapy (CBT) with diabetes education, and was developed
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Educational outcomes and the role of comorbidity among adolescents with type 1-diabetes in Denmark Diabet. Med. (IF 3.5) Pub Date : 2024-01-03 Anne Bonde Thorsted, Lau Caspar Thygesen, Sofie Have Hoffmann, Siri Rosenkilde, Sara Fokdal Lehn, Louise Lundby-Christensen, Trine Allerslev Horsbøl
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Factors influencing participation in an online national diabetes prevention programme: A qualitative study with attenders and educators Diabet. Med. (IF 3.5) Pub Date : 2023-12-27 Clair Haseldine, Grainne O'Donoghue, Patricia M. Kearney, Fiona Riordan, Claire Kerins, Liz Kirby, Margaret Humphreys, Sheena McHugh
To explore factors affecting participation in the pilot of the synchronous online national diabetes prevention programme (NDPP) in Ireland from the perspectives of those who attended and the educators who recruited for and delivered the programme.
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Diabetic complications and risk of depression and anxiety among adults with type 2 diabetes Diabet. Med. (IF 3.5) Pub Date : 2023-12-29 Trine Allerslev Horsbøl, Sofie Have Hoffmann, Anne Bonde Thorsted, Siri Rosenkilde, Sara Fokdal Lehn, Allan Kofoed-Enevoldsen, Monica Santos, Peter Bindslev Iversen, Lau Caspar Thygesen
To investigate if diabetic complications increase the risk of depression and/or anxiety among adults with type 2 diabetes.
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Heterogeneity in glycaemic control in children and adolescents with type 1 diabetes: A latent class trajectory analysis of Danish nationwide data Diabet. Med. (IF 3.5) Pub Date : 2023-12-29 Rasmus Wibaek, Else H. Ibfelt, Gregers S. Andersen, Adam Hulman, Dana Dabelea, Marit E. Jørgensen, Jannet Svensson, Dorte Vistisen, Pernille Falberg Rønn
Suboptimal glycaemic control in children and adolescents with type 1 diabetes is prevalent and associated with increased risk of diabetes-related complications and mortality later in life. First, we aimed to identify distinct glycated haemoglobin (HbA1c) trajectories in children and adolescents (2–19 years) with type 1 diabetes. Second, we examined their associations with clinical and socio-demographic
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Developing and exploring the validity of a patient reported experience measure for adult inpatient diabetes care Diabet. Med. (IF 3.5) Pub Date : 2023-12-27 Olga Kozlowska, Amy Tallett, Samuel Bond, Sarah E. Mansbridge, Helen Aveyard, Crispin Jenkinson, Alexander Dudbridge, Nicky McRobert, Alistair Lumb, Rustam Rea, Garry D. Tan, Helen Walthall
To develop and explore the validity of a Patient Reported Experience Measure (PREM) for adult inpatient diabetes care.
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The antidiabetic SGLT2 inhibitor canagliflozin reduces mitochondrial metabolism in a model of skeletal muscle insulin resistance Diabet. Med. (IF 3.5) Pub Date : 2023-12-23 Lindsey R. VanDerStad, Emily C. Wyatt, Roger A. Vaughan
Sodium-glucose cotransporter 2 (SGLT2) inhibitors such as canagliflozin (CANA) have emerged as an effective adjuvant therapy in the management of diabetes, however, past observations suggest CANA may alter skeletal muscle mass and function. The purpose of this work was to investigate the effects of CANA on skeletal muscle metabolism both with and without insulin resistance.
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Diabetic ulcer alert: Time to rethink our approach to patient adherence Diabet. Med. (IF 3.5) Pub Date : 2023-12-22 Panagiotis Chatzistergos, Nachiappan Chockalingam
Efforts to prevent diabetic foot ulceration (DFU) are undermined by a disconcerting paradox; people with diabetes and diabetic foot complications are advised to avoid wearing inappropriate footwear which can severely injure their feet, but they still keep wearing them anyway.1 The current consensus is that this paradox can be resolved through effective education.2 Even though the importance of patient
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Association between adult food insecurity and mortality among adults aged 20–79 years with diabetes: A population-based retrospective cohort study Diabet. Med. (IF 3.5) Pub Date : 2023-12-23 Pengbo Fu, Jin Wen, Xiaoxia Duan, Xiaowen Hu, Fangyan Chen, Ping Yuan
There is limited research on the relationship between food insecurity and mortality among individuals with diabetes. This study aims to investigate the impact of food insecurity on all-cause and cause-specific mortality in adults with diabetes.
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Vincent Marks (10 June 1930 to 6 November 2023) Diabet. Med. (IF 3.5) Pub Date : 2023-12-21 Peter R. Flatt, Clifford J. Bailey
CONFLICT OF INTEREST STATEMENT The authors have no conflict of interest to declare.
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Real-world study of the concomitant use of biphasic insulin as part 30/70 with GLP-1 receptor agonist versus first-generation basal insulin with GLP-1 receptor agonist in type 2 diabetes Diabet. Med. (IF 3.5) Pub Date : 2023-12-13 Melanie Davies, Amra Ciric Alibegovic, Gayathri Anil, Uffe Christian Braae, Anders Boeck Jensen, Rikke Baastrup Nordsborg
Combining insulin with a glucagon-like peptide-1 receptor agonist (GLP-1RA) to treat type 2 diabetes (T2D) is common. While many studies have investigated concomitant therapy with basal insulin+GLP-1RA, few have reported on premixed insulin+GLP-1RA. We aimed to address this gap using data from the Clinical Practice Research Datalink Aurum database in England.
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An alternative approach using hs-CRP levels and age of onset in diagnostics of HNF1A-MODY Diabet. Med. (IF 3.5) Pub Date : 2023-12-13 Terezia Kickova, Martina Skopkova, Zuzana Dobiasova, Gabriela Lackova, Zita Belicova, Katarina Schenkova, Juraj Stanik, Daniela Gasperikova
The aim is to identify people with HNF1A-MODY among individuals in diabetic cohort solely based on low hs-CRP serum level and early diabetes onset.
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PRIORITY Trial: Results from a feasibility randomised controlled trial of a psychoeducational intervention for parents to prevent disordered eating in children and young people with type 1 diabetes Diabet. Med. (IF 3.5) Pub Date : 2023-12-15 Christina J. Jones, Rebecca Read, Nicola O'Donnell, Katherine Wakelin, Mary John, Simon S. Skene, Rose Stewart, Lucy Hale, Debbie Cooke, Shankar Kanumakala, Rose-Marie Satherley
Children and young people (CYP) with type 1 diabetes (T1D) are at increased risk of disordered eating. This study aimed to determine the feasibility and acceptability of a novel, theoretically informed, two-session psychoeducational intervention for parents to prevent disordered eating in CYP with T1D.
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Real-world lived experience of older adults with type 1 diabetes after an automated insulin delivery trial Diabet. Med. (IF 3.5) Pub Date : 2023-12-10 Erin Kubilay, Steven Trawley, Glenn M. Ward, Spiros Fourlanos, Peter G. Colman, Sybil A. McAuley
First-generation closed-loop automated insulin delivery improves glycaemia and psychosocial outcomes among older adults with type 1 diabetes in clinical trials. However, no study has previously assessed real-world lived experience of older adults using closed-loop therapy outside a trial environment.
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Basic science lays the foundation to success. Diabet. Med. (IF 3.5) Pub Date : 2023-12-01 Claire Hills,Shanta Persaud
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Standardising personalised diabetes care across European health settings: A person-centred outcome set agreed in a multinational Delphi study Diabet. Med. (IF 3.5) Pub Date : 2023-11-28 Ann-Kristin Porth, Anouk Sjoukje Huberts, Alizé Rogge, Angèle Helene Marie Bénard, Angus Forbes, Anja Strootker, Carmen Hurtado Del Pozo, Dagmar Kownatka, David Hopkins, David Nathanson, Henk-Jan Aanstoot, Jeanette Soderberg, Katarina Eeg-Olofsson, Kathryn Hamilton, Laure Delbecque, Lyudmil Ninov, Mette Due-Christensen, Michael Leutner, Rafael Simó, Sara Vikstrom-Greve, Sophia Rössner, Vanesa Flores
Standardised person-reported outcomes (PRO) data can contextualise clinical outcomes enabling precision diabetes monitoring and care. Comprehensive outcome sets can guide this process, but their implementation in routine diabetes care has remained challenging and unsuccessful at international level. We aimed to address this by developing a person-centred outcome set for Type 1 and Type 2 diabetes,
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Does size matter? Hospital volume and resource use in paediatric diabetes care Diabet. Med. (IF 3.5) Pub Date : 2023-11-28 Silvia A. G. de Vries, Jessica C. G. Bak, Dick Mul, Michel W. J. M. Wouters, Max Nieuwdorp, Carianne L. Verheugt, Theo C. J. Sas
Paediatric diabetes care has become increasingly specialised due to the multidisciplinary approach and technological developments. Guidelines recommend sufficient experience of treatment teams. This study evaluates associations between hospital volume and resource use and hospital expenditure in Dutch children with diabetes.
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Satisfaction with diabetes involvement: Exploring parent and adolescent perspectives Diabet. Med. (IF 3.5) Pub Date : 2023-11-27 Jessie J. Wong, Sarah J. Hanes, Haley Flores, Jessica Ngo, Korey K. Hood
Both parent and adolescent involvement in type 1 diabetes management are critical during adolescence. The current study sought to understand the factors associated with parent and adolescent satisfaction with their own and one another's involvement in diabetes management.
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Factors associated with maternal hyperglycaemia and neonatal hypoglycaemia after antenatal betamethasone administration in women with diabetes in pregnancy Diabet. Med. (IF 3.5) Pub Date : 2023-11-28 Christopher W. Rowe, Patrick Rosee, Angeline Sathiakumar, Soundarya Ramesh, Vivian Qiao, Jason Huynh, Georgia Dennien, Natasha Weaver, Katie Wynne
Bespoke glycaemic control strategies following antenatal corticosteroids for women with diabetes in pregnancy (DIP) may mitigate hyperglycaemia. This study aims to identify predictive factors for the glycaemic response to betamethasone in a large cohort of women with DIP.
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Continuous glucose monitoring in older adults with diabetes: Data from the diabetes prospective follow-up (DPV) registry Diabet. Med. (IF 3.5) Pub Date : 2023-11-27 Jennifer Grammes, Stefanie Schmid, Latife Bozkurt, Lutz Heinemann, Gregor Hess, Thomas Kubiak, Eva Küstner, Lilli-Sophie Priesterroth, Christian Stahl, Reinhard W. Holl
To analyse predictors for continuous glucose monitoring (CGM) use in people with diabetes aged ≥60 years using insulin therapy and to assess the rates of CGM use during recent years (2019–2021).
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Insulin independence following islet transplantation improves long-term metabolic outcomes Diabet. Med. (IF 3.5) Pub Date : 2023-11-15 Adam K. Stanley, Kirsty Duncan, Debbie Anderson, Lora Irvine, Andrew Sutherland, Shareen Forbes, John Casey
Pancreatic islet allotransplantation is an effective therapy for type 1 diabetes mellitus, restoring glycaemic control and hypoglycaemic awareness in patients with recurrent severe hypoglycaemia. Insulin independence following transplant is being increasingly reported; however, this is not a primary endpoint in the UK. Having surpassed 10 years of islet transplantation in Scotland, we aimed to evaluate
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tRNA-derived fragments are altered in diabetes Diabet. Med. (IF 3.5) Pub Date : 2023-11-07 N. Ng, H. A. Y. Gibriel, L. Halang, E. Jirström, J. A. Ioana, M. Burke, M. M. Byrne, J. H. M. Prehn
Maternally inherited diabetes and deafness (MIDD) is a rare form of adult-onset diabetes that can be difficult to diagnose due to its variable clinical phenotype. Transfer RNA-derived small fragments are a novel, emerging class of small non-coding RNAs (sncRNAs) that have significant potential as serum biomarkers due to their stress-induced generation, abundance, stability and ease of detection.
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Reliability and validity of a parent-reported screening tool for disordered eating in children and young people with type 1 diabetes Diabet. Med. (IF 3.5) Pub Date : 2023-11-04 Megan P. Harrington, Rose-Marie Satherley, Mary John, Nicola O'Donnell, Rebecca Read, Katherine Wakelin, Christina J. Jones
There is a high prevalence and complex overlap between type 1 diabetes (T1D) and disordered eating. However, screening for disordered eating in children and young people (CYP) with T1D is not routinely conducted, with reluctance reported by both professionals and parents. This study aimed to validate a parent-reported version of a validated disordered eating screening tool for CYP with T1D (the Diabetes
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The journey towards implementation of the NHS Diabetes Prevention Programme: A personal perspective. Diabet. Med. (IF 3.5) Pub Date : 2023-11-01 Jonathan Valabhji
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Evaluation of research and non-research industry payments to endocrinologists in the United States: An analysis of the Open Payments Database from 2014 to 2022 Diabet. Med. (IF 3.5) Pub Date : 2023-11-01 Anju Murayama
Financial collaborations between physicians and the healthcare industry can improve patient care.1 However, these relationships could be conflicts of interest and negatively impact patient care.2 Increasing public demand for greater transparency in physician-industry relationships led the United States to enact the 2010 Physician Payment Sunshine Act,3, 4 mandating that pharmaceutical and medical device
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The Fusion Clinic: Integrating the care of people with severe mental illness and diabetes Diabet. Med. (IF 3.5) Pub Date : 2023-11-01 Sabrina Trappaud Rønne, Anne B. Hansen, Vicki Zabell, Monica Santos, Mette Wallbohm Olsen, Peter Bindslev Iversen, Lise Tarnow, Richard I. G. Holt
People with coexisting severe mental illness (SMI) and type 2 diabetes have a shorter life expectancy and poorer diabetes outcomes than those without SMI. This is partly explained by the separate treatment of diabetes and SMI, which occurs in parallel silos in many healthcare systems. The Steno Diabetes Center Sjaelland and Region Zealand established the Fusion Clinic to offer combined psychiatric
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Can the delivery of behavioural support be improved in the NHS England Low-Calorie Diet Programme? An observational study of behaviour change techniques Diabet. Med. (IF 3.5) Pub Date : 2023-11-01 Tamla S. Evans, Kevin J. Drew, Jim McKenna, Pooja Dhir, Jordan Marwood, Charlotte Freeman, Andrew J. Hill, Lisa Newson, Catherine Homer, Jamie Matu, Duncan Radley, Louisa J. Ells
Previous research has illustrated a drift in the fidelity of behaviour change techniques (BCTs) during the design of the pilot NHS England Low-Calorie Diet (NHS-LCD) Programme. This study evaluated a subsequent domain of fidelity, intervention delivery. Two research questions were addressed: (1) To what extent were BCTs delivered with fidelity to providers programme plans? (2) What were the observed
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Health state utility values for children and adolescents with type 1 diabetes: A systematic review and meta-analysis Diabet. Med. (IF 3.5) Pub Date : 2023-11-01 Shitong Xie, Meixuan Li, Xin Chen, Weihua Guo, Xinran Liu, Kehu Yang, Jing Wu
Type 1 diabetes mellitus (T1DM) is one of the most burdensome chronic diseases in the world. Health utility values are an important tool for quantifying this disease burden and conducting cost-utility analyses. This review aimed to derive a reference set of health utility values for children and adolescents with T1DM.
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Clinical and immunological characteristics of children diagnosed with—Type 1 diabetes during the COVID-19 pandemic Diabet. Med. (IF 3.5) Pub Date : 2023-10-28 Merav Gil Margolis, Sarit Weizman, Liora Lazar, Michal Yakobovich-Gavan, Ariel Tenenbaum, Moshe Phillip, Tal Oron
To find clinical and immunological signatures of the SARS-CoV-2 and the COVID-19 pandemic on children newly diagnosed with type 1 diabetes (T1D).
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Intermittently scanned continuous glucose monitoring in adults with type 1 diabetes: A subgroup analysis from the FLASH-UK study Diabet. Med. (IF 3.5) Pub Date : 2023-10-28 Lalantha Leelarathna, Christopher J. Sutton, Mark L. Evans, Sankalpa Neupane, Gerry Rayman, Sarah Lumley, Iain Cranston, Parth Narendran, Ashma Krishan, Vicky P. Taxiarchi, Katharine Barnard-Kelly, Rachel A. Elliott, Matthew Burns, Maisie Camm, Hood Thabit, Emma G. Wilmot
The FLASH-UK trial showed lower HbA1c with intermittently scanned continuous glucose monitoring (isCGM), as compared with self monitoring of blood glucose (SMBG), in adults with type 1 diabetes and HbA1c ≥58 mmol/mol (≥7.5%). Here, we present results from the pre-specified subgroup analysis for the 24-week HbA1c (primary outcome) and selected sensor-based secondary outcomes.
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A European regulatory pathway for Tidepool loop following clearance in the United States? Diabet. Med. (IF 3.5) Pub Date : 2023-10-24 Laura Downey, Shane O'Donnell, Tom Melvin, Muireann Quigley
The recent clearance by the United States Food and Drug Administration of Tidepool Loop sets an important precedent within the medical device landscape. For the first time, an automated insulin delivery mobile application—based on an algorithm initially designed and developed by users —has been recognised as safe and effective by a regulatory body. The aim of this paper is twofold: firstly, we map
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Glucagon like peptide-1 receptor agonists and the risk of skin cancer among patients with type 2 diabetes: Population-based cohort study Diabet. Med. (IF 3.5) Pub Date : 2023-10-24 Richeek Pradhan, Oriana H. Y. Yu, Robert W. Platt, Laurent Azoulay
The objective of this study was to determine whether the use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) is associated with an increased risk of melanoma and nonmelanoma skin cancer, separately, compared with the use of sulfonylureas among patients with type 2 diabetes.
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Impact of a modified screening approach during the COVID-19 pandemic on the diagnosis and outcomes of gestational diabetes mellitus: A population-level analysis of 90,518 pregnant women Diabet. Med. (IF 3.5) Pub Date : 2023-10-19 Vichy Liyanage, Olesya Barrett, Deliwe Ngwezi, Anamaria Savu, Peter Senior, Roseanne O. Yeung, Sonia Butalia, Padma Kaul
To provide real-world evidence on the uptake of and outcomes associated with the modified gestational diabetes mellitus (GDM) screening approach offered during the COVID-19 pandemic compared with the standard screening approach.