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Plasma adiponectin/leptin ratio associates with subcutaneous abdominal and omental adipose tissue characteristics in women BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-03-14 Eve-Julie Tremblay, André Tchernof, Mélissa Pelletier, Denis R. Joanisse, Pascale Mauriège
A better understanding of adipose tissue (AT) dysfunction, which includes morphological and functional changes such as adipocyte hypertrophy as well as impaired adipogenesis, lipid storage/mobilization, endocrine and inflammatory responses, is needed in the context of obesity. One dimension of AT dysfunction, secretory adiposopathy, often assessed as a low plasma adiponectin (A)/leptin (L) ratio, is
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Secretion of glucagon, GLP-1 and GIP may be affected by circadian rhythm in healthy males BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-03-14 Dorte B. Zilstorff, Michael M. Richter, Jens Hannibal, Henrik L. Jørgensen, Henriette P. Sennels, Nicolai J. Wewer Albrechtsen
Glucagon is secreted from pancreatic alpha cells in response to low blood glucose and increases hepatic glucose production. Furthermore, glucagon enhances hepatic protein and lipid metabolism during a mixed meal. Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are secreted from gut endocrine cells during meals and control glucose homeostasis by potentiating insulin
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Plasma aldosterone response to ACTH stimulation test for diagnosis of primary aldosteronism: a cross-sectional study BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-03-13 Worapaka Manosroi, Pichitchai Atthakomol, Piti Inthaphan, Supornthip Hintong
The diagnosis of primary aldosteronism (PA) requires screening and confirmation testing. The present study examined whether the 1 µg ACTH stimulation test for plasma aldosterone concentration (PAC) can accurately diagnose PA by bypassing the regular confirmatory steps of PA diagnosis. A cross-sectional study with a total of 36 patients with an aldosterone-renin ratio (ARR) > 20 ng/dL per ng/m/hr were
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Circulating levels of asprosin in children with obesity: a systematic review and meta-analysis BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-03-13 Yuwei Zhang, Yifei Zhang, Bao Yang, Simin Li, Ru Jia
Prior studies reported that elevated asprosin level was associated with obesity in adults and animal models. However, the relationship between asprosin level and children with obeisty remains controversial. The aim of our analysis was to systematically review available literatures linking asprosin and children with obesity for a comprehensive understanding of the relationship between circulating asprosin
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L-shaped association between the GA/HbA1c ratio and all-cause mortality in U.S. adults with NAFLD: a cross-sectional study from the NHANES 1999–2004 BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-03-11 Zhaofu Zhang, Hao Wang, Mingyu Chen, Youpeng Chen
It is currently unclear whether there is a relationship between the ratio of glycated albumin to hemoglobin A1c (GA/HbA1c) and mortality in individuals diagnosed with nonalcoholic fatty liver disease (NAFLD). The primary objective of the study was to investigate the relationship between the GA/HbA1c ratio and all-cause mortality in adults with NAFLD in the U.S. The investigation included a total of
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Incidence and determinants of diabetic ketoacidosis among people with diabetes in Woldiya comprehensive specialized hospital, Ethiopia: a retrospective cohort study BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-03-11 Beyene Zewdu, Tefera Belachew, Kemal Ahmed, Lehulu Tilahun, Kirubel Dagnaw
Diabetic ketoacidosis is an acute complication of diabetes mellitus that is characterised by hyperglycemia, acidosis, and ketonuria. Diabetes is the most challenging public health problem in the twenty-first century for both developed and developing countries. To assess the incidence of Diabetic ketoacidosis and its determinants among adult people with diabetes at an Ethiopian Hospital. An institution-based
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Prevalence and prognosis of fulminant type 1 diabetes mellitus in The Middle East: a comparative analysis in a 5-year nationwide cohort BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-03-11 Fateen Ata, Adeel Ahmad Khan, Ibrahim Khamees, Sham AlKodmani, Anas Al-Sadi, Khaled Bani Yaseen, Bassam Muthanna, Angela Godwin, Stephen Frederick Beer, Mohammed Bashir
To analyze the prevalence and progression of fulminant type 1 diabetes (FT1D) in Qatar. This retrospective study analyzed consecutive index- diabetic ketoacidosis (DKA) admissions (2015–2020) among patients with new-onset T1D (NT1D) in Qatar. Of the 242 patients, 2.5% fulfilled the FT1D diagnostic criteria. FT1D patients were younger (median-age 4-years vs.15-years in classic-T1D). Gender distribution
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Therapeutic plasma exchange decreases serum triglyceride level rapidly and reduces early recurrence rate but no advantages in improving outcomes for patients with hyperlipidemic acute pancreatitis: a retrospective propensity score matching analysis based on twenty year’s experience BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-03-06 Canbin Zheng, Yongping Zheng, Zihui Zheng
Hyperlipidaemic acute pancreatitis (HLAP) has become the most common cause of acute pancreatitis (AP) not due to gallstones or alcohol (Mosztbacher et al, Pancreatology 20:608-616, 2020; Yin et al, Pancreas 46:504-509, 2017). Therapeutic plasma exchange (TPE) has been reported to be effective in reducing serum TG levels which is important in management of HLAP (World J Clin Cases 9:5794-803, 2021)
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Skin advanced glycation end-products as indicators of the metabolic profile in diabetes mellitus: correlations with glycemic control, liver phenotypes and metabolic biomarkers BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-03-05 Grigorios Christidis, Frederic Küppers, Senem Ceren Karatayli, Ersin Karatayli, Susanne N. Weber, Frank Lammert, Marcin Krawczyk
The production of advanced glycation end-products (AGEs) is a key pathomechanism related to the complications of diabetes mellitus. The measurement of HbA1c as one of the AGEs is widely used in the clinic, but also other proteins undergo glycation in the course of diabetes. Here, we measure skin AGEs (SAGEs) in patients with diabetes type 1 (DM1) and type 2 (DM2) and correlate them with metabolic markers
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Correlation between the triglyceride-glucose index and arterial stiffness in Japanese individuals with normoglycaemia: a cross-sectional study BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-03-05 Yuying Cai, Wenyue Sha, Hailian Deng, Tuming Zhang, Linlin Yang, Yueying Wu, Jinhua Luo, Guangyan Liu, Yu Yang, Dehui Feng
The association between the triglyceride-glucose (TyG) index and arterial stiffness in individuals with normoglycaemia remains unclear. We aimed to evaluate the relationship between the TyG index and arterial stiffness in Japanese individuals with normoglycaemia, providing additional evidence for predicting early arterial stiffness. This study included 15,453 adults who participated in the NAGALA Physical
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Evaluation of the prevalence of cardiometabolic disorders (diabetes, hypertension, and hyperlipidemia) diagnosed, undiagnosed, treated, and treatment goal in the elderly: Bushehr Elderly Health Program (BEH) BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-03-05 Mahbube Ebrahimpur, Erfan Mohammadi-Vajari, Yasaman Sharifi, Leila Ghotbi, Masoumeh Sarvari, Aryan Ayati, Baran Hashemi, Zhaleh Shadman, Pouria Khashayar, Afshin Ostovar, Noushin Fahimfar, Gita Shafiee, Elnaz Shahmohamadi, Tahereh Yavari, Iraj Nabipour, Bagher Larijani, Moloud Payab, Farshad Sharifi
As the population ages, the global burden of cardiometabolic disorders will increase. This study aimed to investigate the prevalence of cardiometabolic disorders (diabetes, hypertension, and hyperlipidemia) in elderly and to evaluate the effects of various variables including age, sex, education, marital status, smoking, income, physical activity, dementia and depressed mood on untreated cardiometabolic
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Expression and diagnostic value of lncRNA MALAT1 and NLRP3 in lower limb atherosclerosis in diabetes BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-03-04 Juan Li, Chun Wang, Chen Shao, Jiaxin Xu
This study aimed to examine the diagnostic predictive value of long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1(MALAT1) and NOD-like receptor protein 3(NLRP3) expression in patients with type 2 diabetes mellitus(T2DM) and lower extremity atherosclerosis disease (LEAD). A total of 162 T2DM patients were divided into T2DM with LEAD group (T2DM + LEAD group) and T2DM
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Association of serum asprosin with metabolic dysfunction-associated fatty liver disease in older adult type 2 diabetic patients: a cross-sectional study BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-03-04 Junfang Cui, Yunfeng Liu, Mina Li, Jianhong Yin, Jing Yang, Linxin Xu
To explore the association of serum asprosin levels with metabolic dysfunction-associated fatty liver disease (MAFLD) in older adults with type 2 diabetes mellitus (T2DM). The cross-sectional study enrolled patients ≥ 65 years old diagnosed with T2DM at two community health service centers between November 2019 and July 2021. Logistic regression was applied to analyze the influencing factors of MAFLD
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Dietary polyphenols and the risk of metabolic syndrome: a systematic review and meta-analysis BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-03-01 Pushpamala Ramaiah, Kamilya Jamel Baljon, Ahmed Hjazi, Maytham T. Qasim, Omar Abdulwahid Salih Al-ani, Shad Imad, Beneen M. Hussien, Ali Alsalamy, Nazila Garousi
Accumulating evidence has suggested that dietary polyphenols may be protective against metabolic syndrome (MetS); however, the available evidence is contradictory. The aim of this meta-analysis was to assess the association between dietary intake of polyphenols and the odds of MetS. The PubMed and Scopus databases were systematically searched to obtain eligible studies. The risk of MetS for the highest
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First effectiveness data of lenvatinib and pembrolizumab as first-line therapy in advanced anaplastic thyroid cancer: a retrospective cohort study BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-02-22 Dominik Soll, Philip Bischoff, Anne Frisch, Marie Jensen, Zehra Karadeniz, Martina T. Mogl, David Horst, Tobias Penzkofer, Joachim Spranger, Ulrich Keilholz, Knut Mai
Anaplastic thyroid cancer (ATC) is a rare and aggressive neoplasm. We still lack effective treatment options, so survival rates remain very low. Here, we aimed to evaluate the activity of the combination of lenvatinib and pembrolizumab as systemic first-line therapy in ATC. In a retrospective analysis, we investigated the activity and tolerability of combined lenvatinib (starting dose 14 to 24 mg daily)
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Fear of hypoglycemia and illness perception in type II diabetes patients BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-02-20 Abdollahi Fariba, Mohammad Amerzadeh, Marjan Banazadeh, Saba Rashidi, Zahra Tayebi Myaneh
Hypoglycemia, a prevalent acute complication among individuals with type 2 diabetes (T2D), manifests with varied symptoms. Those with diabetes who have previously encountered hypoglycemic episodes commonly develop a Fear of Hyperglycemia (FOH). Illness perception (IP) significantly affects self-care behaviors and health outcomes in individuals diagnosed with T2D. This study examined the correlation
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Effectiveness and safety of dermal matrix used for diabetic foot ulcer: a systematic review and meta-analysis of randomized controlled trials BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-02-20 Lei Sui, Qiang Xie, Hong-tao Jiang, Xiao-dong Li
Diabetic foot ulcers (DFUs) have become a global health concern, which can lead to diabetic foot infection (DFI), lower leg amputation, and even mortality. Though the standard of care (SOC) practices have been recognized as the “gold standard” for DFU care, SOC alone may not be adequate to heal all DFUs and prevent their recurrence. The use of dermal matrix has emerged as an adjuvant treatment to enhance
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Association between weight-adjusted waist index and non-alcoholic fatty liver disease: a population-based study BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-02-18 Changhui Yu, Shiming He, Maobin Kuang, Chao Wang, Xin Huang, Guotai Sheng, Yang Zou
Obesity is the most important driver of non-alcoholic fatty liver disease (NAFLD); nevertheless, the relationship of weight-adjusted waist index (WWI), a new obesity index, with NAFLD is unclear. This retrospective study used data from the NAGALA project from 1994 to 2016. WWI values were calculated using waist circumference (WC) and weight measurements of the participants. Three stepwise adjusted
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Dietary amino acid patterns and cardiometabolic risk factors among subjects with obesity; a cross-sectional study BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-02-14 Fatemeh Abdi, Milad Mohammadzadeh, Mahdieh Abbasalizad-Farhangi
The prevalence of obesity is a growing global public health concern. Certain dietary amino acids have been shown to have a potential therapeutic role in improving metabolic syndrome parameters and body composition in individuals with obesity. However, some amino acids have been linked to an increased risk of cardiometabolic disorders. This cross-sectional study aims to investigate the association between
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Unique case of lymphocytic hypophysitis with normal pituitary hormone serology mimicking a non-functioning pituitary adenoma BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-02-08 Kyle Shen, Catherine Cadang, Daniel Phillips, Varsha Babu
Lymphocytic hypophysitis is a rare autoimmune condition that usually presents during pregnancy and causes inflammation of the pituitary gland. Although the pathophysiology is not well understood, it often presents with headaches, visual disturbances, and symptoms of hypopituitarism. However, not all cases may present with hypopituitarism which can make this rare disease with an incidence of ~ 1 in
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Clinical application of combination [11C]C-methionine and [13N]N-ammonia PET/CT in recurrent functional pituitary adenomas with negative MRI or [18F]F-FDG PET/CT BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-02-05 Zongming Wang, Zize Feng, Dimin Zhu, Xin Wang, Jinping Chen, Yonghong Zhu, Haijun Wang
We assessed the value of positron emission tomography/computed tomography (PET/CT) with [13N]N-ammonia ([13N]N-NH3) and [11C]C-methionine ([11C]C-MET) for the evaluation and management of recurrent secreting pituitary adenoma, which could not be detected by magnetic resonance imaging (MRI) or fluorine-18 fluorodeoxyglucose ([18F]F-FDG) PET. Nine consecutive patients with biochemical and clinical evidence
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The associations of risk of cardiovascular disease with development stages of diabetes in Chinese population: findings from a retrospective cohort study in QuZhou city BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-02-02 Qi Wang, Zhijuan Gan, Qing Gao, Meng Wang, Bingdong Zhan
Risk analysis is an important area of research in diabetes and cardiovascular disease (CVD), both of which have significant global health burdens. Although there is evidence that patients with prediabetes and diabetes mellitus may have an increased risk of CVD, few studies have been conducted in mainland China. This retrospective cohort study utilized data from the Quzhou City Resident Health Information
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Associations of triglyceride-glucose index with hyperuricemia among Royal Thai Army personnel BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-02-01 Sethapong Lertsakulbunlue, Tanatip Sangkool, Varathpavee Bhuriveth, Mathirut Mungthin, Ram Rangsin, Anupong Kantiwong, Boonsub Sakboonyarat
Hyperuricemia has placed an immense burden on the global healthcare system. Studies have discovered a close correlation between serum uric acid (SUA) and insulin resistance (IR). The objective of this investigation is to examine the association between the triglyceride-glucose (TyG) index, a simple surrogate for IR, and the presence of hyperuricemia. Between 2017 and 2021, an epidemiologic study was
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Follicular adenoma with a papillary architecture originating from an ectopic thyroid gland: a case report BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-01-30 Kiyomi Kuba, Tomonori Kawasaki, Yuichiro Enoki, Hitoshi Inoue, Satoko Matsumura, Tomoko Yamazaki, Yasuhiro Ebihara, Mitsuhiko Nakahira, Masashi Sugasawa
Follicular adenomas with papillary architecture are rare tumors of thyroid origin and are composed of completely encapsulated follicular cells with a papillary architecture lacking the nuclear characteristics of papillary carcinoma. Herein, we present a case of follicular adenoma with papillary architecture originating from an ectopic thyroid gland, diagnosed from a mass in the submandibular region
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Association between thymic hyperplasia and serum calcium level in Graves’ disease BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-01-29 Jing Zeng, Lan Li, Dong Wei
Graves' disease increases bone resorption in hyperthyroidism, leading to elevated serum calcium levels and a negative bone balance. Thymic hyperplasia is observed in some Graves' disease patients. What's more, there have been a few reports of increased serum calcium and severe osteoporosis induced by Graves’ disease with thymic hyperplasia. It remains unclear whether Graves’ disease with thymic hyperplasia
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A follow-up study on factors affecting the recovery of patients with hypothyroidism in different selenium environments BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-01-29 Si Wang, Ping Chen, Yayi He, Jing Wei, Li Tian, Yajun Wu, Hongjun Lv, Xiaogang Peng, Xingru Zhang, Bingyin Shi, Qian Wu
Hypothyroidism is a major manifestation of autoimmune thyroid diseases (AITD). We previously reported that a low selenium (Se) status was linked to an elevated prevalence of thyroid diseases. We hypothesized that Se status may also influence the restoration of thyroid function. Thus, this study aimed to investigate the factors affecting the recovery of thyroid function in patients with (sub-)clinical
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Recurrent acromegaly: a systematic review on therapeutic approaches BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-01-26 Seyed Farzad Maroufi, Mohammadmahdi Sabahi, Seyed Sahab Aarabi, Mohammad Samadian, Rocco Dabecco, Badih Adada, Karla M. Arce, Hamid Borghei-Razavi
Management of recurrent acromegaly is challenging for both neurosurgeons and endocrinologists. Several treatment options including repeat surgery, medical therapy, and radiation are offered for such patients. The efficacy of these modalities for the treatment of recurrence has not been studied previously in the literature. In this study, we aim to systematically review the existing cases of recurrence
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Combined glucocorticoids and cyclophosphamide in the treatment of Graves’ ophthalmopathy: a systematic review and meta-analysis BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-01-26 Qilang Xiang, Mengling Yang, Wenxuan Luo, Yuzi Cao, Shiquan Shuai, Xin Wei, Anji Xiong
To evaluate the efficacy and safety of combined glucocorticoids (GCs) and cyclophosphamide (CYC) treatment in Graves’ ophthalmopathy (GO). We searched PubMed, Embase, Cochrane Library, and four Chinese databases (Chinese National Knowledge Infrastructure (CNKI), China Science and Technology Journal Database (VIP), WanFang, and SinoMed) for any published randomized controlled trials (RCTs) produced
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Correction: Association between serum osteocalcin and atherosclerosis in type-2 diabetes mellitus: a cross-sectional study BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-01-19 Vishal Chandra Sharma, Sudha Vidyasagar, Cynthia Amrutha Sukumar, Nanda Krishna B, Sharanya Shree
Correction: BMC Endocr Disord 23, 269 (2023) https://doi.org/10.1186/s12902-023-01462-8 Following publication of the original article [1], the authors reported that the abbreviation “KMC” should be “Kasturba Medical College” in affiliation 1. The correct affiliation 1 should read: Department of Medicine, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India. The original
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Nutrient patterns and risk of diabetes mellitus type 2: a case-control study BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-01-17 Morteza haramshahi, Thoraya Mohamed Elhassan A-Elgadir, Hamid Mahmood Abdullah Daabo, Yahya Altinkaynak, Ahmed Hjazi, Archana Saxena, Mazin A.A. Najm, Abbas F. Almulla, Ali Alsaalamy, Mohammad Amin Kashani
Although the significance of diet in preventing or managing diabetes complications is highlighted in current literature, there is insufficient evidence regarding the correlation between nutrient patterns and these complications. The objective of this case-control study is to investigate this relationship by analyzing the dietary intake of nutrients in participants with and without type 2 diabetes (T2D)
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Elevated serum CA199 levels in patients suffering type 2 diabetes vs. various types of cancer BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-01-12 Yong Zhuang, Qingyan Cai, Xin Hu, Huibin Huang
Carbohydrate antigen 199 (CA199) is a standard tumor marker, and recent studies have found elevated in CA199 levels in patients with diabetes. However, there is no systematic measurement and comparison of serum CA199 levels in patients with diabetes and cancer. Here, a detailed description of the changes in serum CA199 levels in patients with type 2 diabetes and various cancers was explored. A total
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Genetic variants of ABCC8 and clinical manifestations in eight Chinese children with hyperinsulinemic hypoglycemia BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-01-12 Guoying Chang, Lingwen Ying, Qianwen Zhang, Biyun Feng, Ruen Yao, Yu Ding, Juan Li, Xiaodong Huang, Yongnian Shen, Tingting Yu, Jian Wang, Xiumin Wang
ABCC8 variants can cause hyperinsulinemia by activating or deactivating gene expression. This study used targeted exon sequencing to investigate genetic variants of ABCC8 and the associated phenotypic features in Chinese patients with hyperinsulinemic hypoglycemia (HH). We enrolled eight Chinese children with HH and analyzed their clinical characteristics, laboratory results, and genetic variations
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Prediabetes remission after bariatric surgery: a 4-years follow-up study BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-01-11 Marta Borges-Canha, João Sérgio Neves, Maria Manuel Silva, Fernando Mendonça, Telma Moreno, Sara Ribeiro, Catarina Vale, Juliana Gonçalves, Helena Urbano Ferreira, Sara Gil-Santos, Raquel Calheiros, Inês Meira, João Menino, Vanessa Guerreiro, Jorge Pedro, Ana Sande, Selma B. Souto, Eduardo Lima da Costa, Davide Carvalho, Paula Freitas
Bariatric surgery leads to weight loss and to cardiometabolic risk improvement. Although prediabetes remission after bariatric surgery is biologically plausible, data on this topic is scarce. We aimed to assess prediabetes remission rate and clinical predictors of remission in a 4 year follow up period. Observational longitudinal study including patients with obesity and prediabetes who had undergone
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Effects of conditioned media derived from human Wharton’s jelly mesenchymal stem cells on diabetic nephropathy and hepatopathy via modulating TGF-β and apelin signaling pathways in male rats BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-01-05 Zeinab Karimi, Gholamreza Daryabor, Fatemeh Masjedi
Diabetic nephropathy and hepatopathy are health problems described by specific renal and hepatic structure and function disturbances. The protective effects of the stem cell secretome have been shown in several kidney and liver diseases. The current study aims to evaluate the capability of conditioned media derived from human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs-CM) to alleviate diabetic
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The prevalence of thyroid disorders in COVID-19 patients: a systematic review and meta-analysis BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-01-02 Sadra Ashrafi, Hossein Hatami, Razieh Bidhendi-Yarandi, Mohammad Hossein Panahi
To conduct a systematic review and meta-analysis to evaluate the prevalence of thyroid disorders in COVID-19 patients. Scopus, PubMed, ISI Web of Science, and Google Scholar databases were used in this review. We also consider the results of grey literature. Cohort, cross-sectional, and case-control studies were included. The required data were extracted by the first author of the article and reviewed
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Lipid variability and risk of microvascular complications in patients with diabetes: a systematic review and meta-analysis BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-01-02 Mohammad Amin Karimi, Ali Vaezi, Akram Ansari, Iman Archin, Kiarash Dadgar, Asma Rasouli, Parna Ghannadikhosh, Goharsharieh Alishiri, Neda Tizro, Fatemeh Gharei, Saba Imanparvar, Sakineh Salehi, Seyed Amirhossein Mazhari, Mohammad Hossein Etemadi, Milad Alipour, Niloofar Deravi, Mahdyieh Naziri
The current systematic review aimed to elucidate the effects of lipid variability on microvascular complication risk in diabetic patients. The lipid components studied were as follows: High-density lipoprotein (HDL), High-density lipoprotein (LDL), Triglyceride (TG), Total Cholesterol (TC), and Remnant Cholesterol (RC). We carried out a systematic search in multiple databases, including PubMed, Web
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“Once I take that one bite”: the consideration of harm reduction as a strategy to support dietary change for patients with diabetes BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-01-02 Alexzandra T. Gentsch, Megan K. Reed, Amy Cunningham, Anna Marie Chang, Stephanie Kahn, Danielle Kovalsky, Amanda M. B. Doty, Geoffrey Mills, Judd E. Hollander, Kristin L. Rising
Despite well-established guidelines to treat diabetes, many people with diabetes struggle to manage their disease. For many, this struggle is related to challenges achieving nutrition-related lifestyle changes. We examined how people with diabetes describe barriers to maintaining a healthy diet and considered the benefits of using a harm reduction approach to assist patients to achieve nutrition-related
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Dyslipidemia and hyperuricemia: a cross-sectional study of residents in Wuhu, China BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-01-02 Yicheng Fang, Wendan Mei, Chenxu Wang, Xia Ren, Jian Hu, Fan Su, Lei Cao, Grace Tavengana, Mingfei Jiang, Huan Wu, Yufeng Wen
While dyslipidemia has been recognized as a potential risk factor for hyperuricemia, there is currently a dearth of large-scale data specifically focused on studying the relationship between these two conditions. To address this gap, the present study analyzed a dataset of 298,891 physical examination records to investigate in greater detail the clinical classification and compositional relationship
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Correction: The association between creatinine to body weight ratio and the risk of progression to diabetes from pre-diabetes: a 5-year cohort study in Chinese adults BMC Endocr. Disord. (IF 2.7) Pub Date : 2024-01-02 Tong Li, Changchun Cao, Xuan Xuan, Wenjing Liu, Xiaohua Xiao, Cuimei Wei
Correction: BMC Endocr Disord 23, 266 (2023) https://doi.org/10.1186/s12902-023-01518-9 Following publication of the original article [1], the authors reported that the funding information was mistakenly missing in the article. The correct Funding section should read: This study were supported by Shenzhen Key Medical Discipline Construction Fund (SZXK009), Shenzhen Municipal Science and Technology
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Umbilical artery cord blood glucose predicted hypoglycemia in gestational diabetes mellitus and other at-risk newborns BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-12-21 Yuan Wang, Huahua Liu, Leilei Zhang, Xin Wang, Mingbo Wang, Zhifang Chen, Feng Zhang
To explore the value of umbilical artery cord blood glucose (UACBG) in predicting hypoglycemia in gestational diabetes mellitus (GDM) and other at-risk newborns, and to provide a cut-off UACBG value for predicting hypoglycemia occurrence. In this prospective study, we enrolled at-risk infants delivered vaginally, including neonates born to mothers with GDM, premature, macrosomic, and low birth weight
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Challenges in the diagnosis of the enigmatic primary adrenal leiomyosarcoma: two case reports and review of the literature BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-12-18 Sawako Suzuki, Naoya Takahashi, Masafumi Sugo, Kazuki Ishiwata, Akiko Ishida, Suzuka Watanabe, Katsushi Igarashi, Yutaro Ruike, Kumiko Naito, Masanori Fujimoto, Hisashi Koide, Yusuke Imamura, Shinichi Sakamoto, Tomohiko Ichikawa, Yoshihiro Kubota, Takeshi Wada, Yuto Yamazaki, Hironobu Sasano, Jun-ichiro Ikeda, Ichiro Tatsuno, Koutaro Yokote
Primary adrenal leiomyosarcoma is a rare and aggressive mesenchymal tumor derived from the smooth muscle wall of a central adrenal vein or its tributaries; therefore, tumors tend to invade the inferior vena cava and cause thrombosis. The great majority of tumors grow rapidly, which makes the disease difficult to diagnose in its early clinical stages and needs differentiation from adrenocortical carcinomas
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Soluble receptor for advanced glycation end products (sRAGE) is associated with obesity rates: a systematic review and meta-analysis of cross-sectional study BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-12-15 Nahla A Tayyib, Pushpamala Ramaiah, Shadia Hamoud Alshahrani, Ria Margiana, Sami G. Almalki, A. K. Kareem, Rahman S. Zabibah, Abdullah M. Shbeer, Saad Hayif Jasim Ali, Yasser Fakri Mustafa
Several studies have highlighted the possible positive effects of soluble receptor for advanced glycation end products (sRAGE) against obesity. However, due to their inconsistent results, this systematic review and meta-analysis aimed to quantitatively evaluate and critically review the results of studies evaluating the relationship between sRAGE with obesity among adult population. In the systematic
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Hyperglycemia with hypogonadism and growth hormone deficiency in a 17-year-old male with H syndrome: the first case report from Syria BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-12-14 Suaad Hamsho, Mohammed Alaswad, Mouhammed Sleiay, Ayham Alhusseini
The nucleoside transport capabilities of the human equilibrative nucleoside transporter-3 (hENT3) are disrupted by mutations in SLC29A3 (10q22.2), which are genes for the nucleoside transporter and are the cause of the unusual autosomal recessive disease known as H syndrome. As a result, histiocytic cells invade a number of organs. A 17-year-old Syrian male was admitted to the internal medicine department
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Glycemic control and associated factors among type 2 diabetes mellitus patients: a cross-sectional study of Azar cohort population BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-12-12 Masoud Faghieh Dinavari, Sarvin Sanaie, Kimia Rasouli, Elnaz Faramarzi, Roghayeh Molani-Gol
Despite the growing prevalence of diabetes and its complications, there is a dearth of data regarding factors associated with glycemic control. Therefore, in this cross-sectional study, we aimed to identify factors influencing glycemic control in patients with type 2 diabetes mellitus (T2DM) in the Iranian population. This cross-sectional study was conducted among the Azar cohort population and the
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Increased circulating FGF21 level predicts the burden of metabolic demands and risk of vascular diseases in adults with type 2 diabetes BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-12-07 Zhen Liu, Yue Peng, Supeng Li, Yusheng Lin, Yunfeng Huang, Wenting Chen, Chunhua Bao, Zengxian Zhou, Zhuofeng Lin, Liangmiao Chen
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by chronic hyperglycemia and metabolic stress, involved in the stepwise development of cardiovascular complications. Fibroblast growth factor 21 (FGF21) is a novel hepatokine involved in regulating glucose and lipid metabolism, and has been linked to the prediction, treatment, and improvement of prognosis in multiple cardiovascular
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m6A modification patterns are associated with copy number burden and tumor immune landscape in thyroid cancer BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-12-06 Liangliang Cai, Tingting Liu, Hujia Hua, Xingyu Jiang, Li Qian
The association involving N6-methyladenosine (m6A) modification, molecular subtype and specific immune cell group in tumor microenvironment has been the focus of recent studies. The underlying function of m6A modification in thyroid cancer (TC) remains elusive. The m6A modification regulations, molecular character and tumor immune profile of 461 TC patients were explored and then the correlation between
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Increased prevalence of thyroid dysfunction in Tehran – HAMRAH study BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-12-06 Zahra Ghaemmaghami, Parisa Firoozbakhsh, Delara Gholami, Sajad Khodabandelu, Mohammadreza Baay, Mohammad Javad Alemzadeh-Ansari, Bahram Mohebbi, Zahra Hosseini, Shabnam Boudagh, Hamidreza Pouraliakbar, Yeganeh Pasebani, Ali Rafati, Ehsan Khalilpour, Yasaman Khalili, Maedeh Arabian, Majid Maleki, Hooman Bakhshandeh, Parham Sadeghipour
The aim of the current study is to assess the prevalence of different categories of thyroid dysfunction and their associated risk factors among the modern urban population of Tehran, the capital of Iran. The present investigation is a sub-study of the HAMRAH study, a population-based prospective study designed to assess the prevalence of traditional cardiovascular risk factors and their changes through
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Association between serum osteocalcin and atherosclerosis in Type-2 diabetes mellitus: a cross-sectional study BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-12-06 Vishal Chandra Sharma, Sudha Vidyasagar, Cynthia Amrutha Sukumar, Nanda Krishna B, Sharanya Shree
The past few decades have seen a marked increase in the macrovascular complications of Type-2 diabetes mellitus (T2DM) such as coronary heart disease, peripheral arterial disease, and cerebrovascular disease. This has been predominantly attributed to the increased atherosclerosis in these patients. Atherosclerosis usually remains an asymptomatic condition and this poses a significant challenge in its
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Status of lipid control in Bangladeshi subjects with type 2 diabetes mellitus on lipid-lowering drugs: a multicenter, facility-based, cross-sectional study BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-12-05 Shahjada Selim, Muhammad Shah Alam, Samir Kumar Talukder, Md Lutful Kabir, Abu Jar Gaffar, Md Ahamedul Kabir, Nusrat Zarin, Shahin Ibn Rahman, Md Masud Un Nabi, Marufa Mustari, Md Firoj Hossain, Ahmed Ifrad Bin Raunak, Md Azizul Hoque, Md Rashedul Islam, Farhana Akter, Mohammad Abdul Hannan, Mohammad Saifuddin, Md Asaduzzaman, Mohammad Motiur Rahman, Afsar Ahammed, Md Abdur Rafi, Mohammad Jahid Hasan
Achievement of lipid targets is crucial in patients with type 2 diabetes mellitus (T2DM) to mitigate the risk of cardiovascular diseases (CVD). Data on lipid-control status among patients with T2DM in Bangladesh are scarce. This study was conducted to determine the lipid-control status among patients with T2DM who were on lipid-lowering drugs in the country. This cross-sectional study was conducted
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Association between the MCP-1 -2518 A > G (rs1024611) polymorphism and susceptibility to type 2 diabetes mellitus and diabetic nephropathy: a meta-analysis BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-12-04 Wei-wei Chang, Liu Zhang, Li-ying Wen, Yu-jing Tao, Jia-jie Xiong, Xin Tong, Yue-long Jin, Hong Su
Studies evaluating the association between monocyte chemoattractant protein-1 (MCP-1) -2518 A > G (rs1024611) polymorphism and type 2 diabetes mellitus (T2DM) and diabetic nephropathy (DN) are contradictory. The present study aims to provide a comprehensive assessment and more reliable estimation of the relationship between the MCP-1 rs1024611 polymorphism and T2DM and DN risk. Eligible articles were
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The association between creatinine to body weight ratio and the risk of progression to diabetes from pre-diabetes: a 5-year cohort study in Chinese adults BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-12-04 Tong Li, Changchun Cao, Xuan Xuan, Wenjing Liu, Xiaohua Xiao, Cuimei Wei
Evidence on the association between the creatinine to body weight (Cre/BW) ratio and the risk of pre-diabetes to diabetes development remains limited. Our study aimed to examine the association between the Cre/BW ratio and incident diabetes in pre-diabetic patients. This retrospective cohort study included 24,506 pre-diabetic participants who underwent health checks from 2010 to 2016 in China. We used
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Prevalence and associated factors of foot deformity among adult diabetic patients on follow-up at Debre Markos comprehensive specialized hospital, Northwest Ethiopia, 2022, cross-sectional study BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-11-30 Aderajew Agmass Adebabay, Amanuel Girma Worede, Bickes Wube Sume, Getachew Tilaye Mihiret, Rahel Asres Shimelash, Bahiru Tenaw Goshu
Diabetes foot deformity is among the major causes of diabetic foot ulceration, resulting in lower limb amputation. However, the study on the distribution of foot deformity and its risk factor among diabetic patients in Ethiopia is limited. This study determined the overall prevalence and associated factors of foot deformity among adult diabetic patients on follow-up at Debre Markos Comprehensive Specialized
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Thyroid function and opium use disorder: a cross-sectional study on the Fasa adults cohort study (FACS), 2017 BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-11-30 Babak Pezeshki, Hossein Pourmontaseri, Reza Homayounfar, Maryam Talebi Moghaddam, Azizallah Dehghan
Addiction increases the risk of different lifelong disorders. However, there are limited studies evaluating the effects of opioid use disorder (OUD) on thyroid function. The present study aimed to compare the thyroid function of individuals with and without OUD. This cross-sectional study was conducted on 700 eligible participants of the Persian Cohort of Fasa, Iran. Pregnant women and participants
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Bilateral co-secretory lesions presenting with coexisting Cushing syndrome and primary aldosteronism: a case report BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-11-29 Hongjiao Gao, Li Li, Fei Chen, Yan Ren, Tao Chen, Haoming Tian
There is an increasing number of cases of aldosterone- and cortisol-producing adenomas (A/CPAs) reported in the context of primary aldosteronism (PA). Most of these patients have PA complicated with subclinical Cushing's syndrome; cases of apparent Cushing's syndrome (CS) complicated with aldosteronism are less reported. However, Co-secretory tumors were present in the right adrenal gland, a cortisol-secreting
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Glycemic variability and time in range among children with type 1 diabetes on insulin pump during the Covid-19 pandemic in Egypt; single center experience BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-11-27 Abeer Ahmed Abdel Maksoud, Nouran Yousef Salah, Safaa Alshraki Alsayed Ayoup
Covid-19 has impacted the lives of individuals worldwide especially those with chronic illnesses. Children with type 1 diabetes (T1DM) are at risk of glycemic deterioration during the Covid-19 pandemic. However, some studies reported glycemic improvement in these children during the pandemic. To assess the impact of Covid-19 on glycemic control and acute complications among children with T1DM on insulin
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Dietary polyphenol intake, body composition and components of metabolic syndrome in a sample overweight and obese adults: a cross-sectional study BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-11-27 Shadia Hamoud Alshahrani, Zaid Al-Attar, Hamid Mahmood Abdullah Daabo, Najim Z. Alshahrani, Sarmad Ghazi Al-Shawi, Edgar Froilan Damián Núñez, Beneen M. Hussien, Ahmed Hjazi, Zahraa F. Hassan
The health benefits of dietary polyphenol intake (DPI) including improved lipid profiles, blood pressure, insulin resistance, and reduced systemic inflammation has revealed previously. However, the results of numerous studies are not consistent and it seems that these health effects are attributed to some of DPI. In the current research, we evaluated the health benefits of DPI on metabolic markers
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A prediction model for identifying high-risk lymph node metastasis in clinical low-risk papillary thyroid microcarcinoma BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-11-27 Hui Huang, Yunhe Liu, Song Ni, Shaoyan Liu
The presence of high-volume lymph node metastasis (LNM) and extranodal extension (ENE) greatly increases the risk of recurrence in patients with low-risk papillary thyroid microcarcinoma (PTMC). The goal of this research was to analyze the factors that contribute to high-risk lymph node metastasis in patients with low-risk PTMC. We analyzed the records of 7344 patients who were diagnosed with low-risk
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Effect of coadministration of omega-3 fatty acids with glimepiride on glycemic control, lipid profile, irisin, and sirtuin-1 in type 2 diabetes mellitus patients: a randomized controlled trial BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-11-25 Rehab H. Werida, Aalaa Ramzy, Youssri Nassief Ebrahim, Maged Wasfy Helmy
Type 2 diabetes mellitus (T2DM) is caused by insulin resistance or tissue insensitivity to insulin, as well as relative insulin insufficiency. Diabetes that is uncontrolled for an extended period of time is linked to substantial comorbidities and organ damage. The purpose of the current study is to assess the effect of coadministration of omega-3 fatty acids with glimepiride on blood glucose, lipid
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Primary adrenal diffuse large B cell Lymphoma with Tumor thrombus in central adrenal vein: a case report and literature review BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-11-24 Qingfei Xing, Chunhai Hu, Qingqing Zhao, Chunling Zhang, Tingshuai Cao, Xinghua Gao, Li He, Feng Guo
Primary adrenal lymphoma (PAL) is a rare disease confined wholly or chiefly to extramural involvement. Tumor thrombus in the central adrenal vein, renal vein, and inferior vena cava has been reported in adrenal pheochromocytoma, adrenocortical carcinoma, adrenal metastasis carcinoma, and adrenal leiomyosarcoma. Primary adrenal diffuse large B cell lymphoma with tumor thrombus in the central adrenal
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The effect of sodium-glucose co-transporter-2 (SGLT2) inhibitors on blood interleukin-6 concentration: a systematic review and meta-analysis of randomized controlled trials BMC Endocr. Disord. (IF 2.7) Pub Date : 2023-11-24 Sepehr Gohari, Faramarz Ismail-Beigi, Mahsa Mahjani, Saeed Ghobadi, Alireza Jafari, Hassan Ahangar, Sheida Gohari
The low-grade chronic inflammation in diabetes plays an important role in development of cardiovascular and renal complications. Sodium-glucose co-transporter-2 (SGLT2) inhibitors are recognized as protective agents for cardio-renal complications. Interleukin-6 (IL-6) is positively associated with the pathophysiology of metabolic-related pathologies. The aim of this meta-analysis is to investigate