-
Arteriosclerosis and atherosclerosis assessment in clinical practice: Methods and significance Pulse Pub Date : 2023-04-12 Jeong Bae Park, Alberto Avolio
Alongside cancer, cardiovascular disease (CVD) exhibits the highest rates of morbidity and mortality globally, in western society as well as in Asian countries. Aging is a serious problem for the Asian population as progression towards a super-aged society is moving at a remarkably high rate. This increased rate of aging leads to increased CVD risk and, consequently, high CVD incidence. However, aging
-
-
Expert Consensus on the Clinical Use of Pulse Wave Velocity in Asia Pulse Pub Date : 2022-11-22 Jeong Bae Park, James E. Sharman, Yan Li, Masanori Munakata, Kohji Shirai, Chen-Huan Chen, Sae Young Jae, Hirofumi Tomiyama, Hisanori Kosuge, Rosa Maria Bruno, Bart Spronck, Kazuomi Kario, Hae Young Lee, Hao-Min Cheng, Jiguang Wang, Matthew Budoff, Raymond Townsend, Alberto P. Avolio
Arterial stiffness is a progressive aging process that predicts cardiovascular disease. Pulse wave velocity (PWV) has emerged as a noninvasive, valid, and reliable measure of arterial stiffness and an independent risk predictor for adverse outcomes. However, up to now PWV measurement has mostly been used as a tool for risk prediction and has not been widely used in clincial practice. This consensus
-
The relationship of Vascular Aging to Reduced Cognitive Function: Pulsatile and Steady State Arterial Hemodynamics Pulse Pub Date : 2022-11-18 Wei-Ting Wang, Wei-Lun Chang, Hao-Min Cheng
Aortic stiffness increases with age and is a robust predictor of cerebrovascular events and cognitive decline including Alzheimer’s disease and other forms of dementia. Recent clinical studies have investigated the association between proximal aortic stiffness and pulsatile energy transmission that have deleterious effects on the cerebrovascular network in order to identify potential therapeutic targets
-
-
Relationship between Fragmented QRS and Microvascular Dysfunction in Masked Hypertension Pulse Pub Date : 2022-06-24 Ragab A. Mahfouz, Mohamed Mesbah, Marwa M. Gad, Moheye Abulfotouh, Mohamed Arab
Aim: The aim of this study was to investigate the presence of fQRS and its association with subclinical systolic and microvascular dysfunction in patients with masked hypertension (MH). Methods: The study population consisted of 95 (mean age 48.9 ± 11.3, 61% males) subjects with MH and 80 age- and gender-matched healthy individuals who served as a control group. Coronary flow reserve (CFR) using transthoracic
-
An Unexpected Cause of Severe Hypertension and Bradycardia: The Role of Hemodynamic Assessment by Echocardiography Pulse Pub Date : 2022-06-14 Gard M.S. Myrmel, Abukar Ali, Torbjørn Lunde, Giuseppe Mancia, Sahrai Saeed
Severe hypertension has numerous etiologies. When accompanied by bradycardia, the spectrum of differential diagnoses is greatly narrowed and is commonly seen in patients with increased intracranial pressure. However, other etiologies such as bradycardia-induced hypertension are rarely mentioned. Here we report the case of a 73-year-old woman presenting with symptoms of heart failure, severe hypertension
-
Cuffless Measurement of Blood Pressure: Not Good Enough for Diagnosis and Treatment of Hypertension Pulse Pub Date : 2022-05-03 Hao-Min Cheng, Chen-Huan Chen
Pulse
-
Challenges Presented by Cuffless Measurement of Blood Pressure if Adopted for Diagnosis and Treatment of Hypertension Pulse Pub Date : 2022-04-22 Alberto Avolio, James Cox, Kyrollos Louka, Fatemeh Shirbani, Isabella Tan, Ahmad Qasem, Mark Butlin
The global health burden presented by hypertension is providing increased motivation for improved means of collection of blood pressure (BP) data. A growing area of research and commercial activity is the use of wearable devices to provide BP data using non-invasive cuffless techniques. The accelerated progress in recent years, particularly relating to connectivity of smartphone technology, has promoted
-
-
-
Relation between Oscillometric Measurement of Central Hemodynamics and Left Ventricular Hypertrophy in Hypertensive Patients Pulse Pub Date : 2021-11-30 Masakazu Obayashi, Shigeki Kobayashi, Takuma Nanno, Yoriomi Hamada, Masafumi Yano
Introduction: The augmentation index (AIx) or central systolic blood pressure (SBP), measured by radial applanation tonometry, has been reported to be independently associated with left ventricular hypertrophy (LVH) in Japanese hypertensive patients. Cuff-based oscillometric measurement of the AIx using Mobil-O-Graph® showed a low or moderate agreement with the AIx measurement with other devices. Methods:
-
Presence of Microvascular Dysfunction and CHA2DS2-VASc Score in Patients with ST-Segment Myocardial Infarction after Primary Percutaneous Coronary Intervention Pulse Pub Date : 2021-11-26 Ragab A. Mahfouz, Marwa M. Gad, Mohamed Arab, Moei-E. deen Abulfotouh
Objective: We aimed to investigate the relation between CHA2DS2-VASc score and microvascular dysfunction (MVD) assessed by the index of microvascular resistance (IMR) immediately after primary percutaneous intervention (PPCI) for patients with ST-segment elevation myocardial infarction (STEMI). Subjects and Methods: The study included 115 consecutive patients with STEMI who underwent successful PPCI
-
Circulating Serum Copper Is Associated with Atherosclerotic Cardiovascular Disease, but Not Venous Thromboembolism: A Prospective Cohort Study Pulse Pub Date : 2021-11-19 Setor K. Kunutsor, Richard S. Dey, Jari A. Laukkanen
Background and Objective: Serum copper has been linked to the risk of atherosclerotic cardiovascular disease (CVD). However, the potential association between serum copper and venous thromboembolism (VTE) is not known. The principal aim was to evaluate the potential prospective association between serum copper and VTE risk. A secondary aim was to confirm or refute previously reported associations between
-
Brachial Artery “Low-Flow Mediated Constriction” Is Associated with Myocardial Perfusion Defect Severity and Mediated by an Altered Flow Pattern during Occlusion Pulse Pub Date : 2021-11-18 Smriti Badhwar, Dinu S. Chandran, Ashok K. Jaryal, Rajiv Narang, Chetan Patel, Kishore Kumar Deepak
Introduction: The relationship between low flow-mediated constriction (LFMC), a new proposed measure of endothelial function, with cardiovascular disease severity and its hypothesized stimulus, that is, low flow, has not been comprehensively evaluated. The study evaluated association between change in brachial artery diameter during constriction with severity of myocardial perfusion defect (PD) and
-
Assessment of Arterial Stiffness, Brachial Haemodynamics, and Central Haemodynamics in Diabetic Hypertensives: A Pulse Wave Analysis-Based Case-Control Study from an Urban Area of West India Pulse Pub Date : 2021-10-25 Jayesh Dalpatbhai Solanki, Sunil J. Panjwani, Ravi Kanubhai Patel, Devanshi Nishantbhai Bhatt, Param Jagdeep Kakadia, Chinmay J. Shah
Introduction: Hypertension (HTN) and diabetes frequently coexist, imposing significant cardiovascular risk that is normally studied in terms of brachial blood pressure (bBP). Direct and superior parameters like central haemodynamics and arterial stiffness are studied scarcely. Pulse wave analysis (PWA) offers a non-invasive measurement of the same that we studied in diabetic hypertensives. Materials
-
High Signal Resolution Pulse Oximetry as a Prognostic Indicator of Radiotherapy Toxicity: A Pilot Study Pulse Pub Date : 2021-10-21 Karolina Jezierska, Agnieszka Macała, Ryszard Krzyminiewski, Piotr Woźniak, Magdalena Łukowiak, Anna Sękowska-Namiotko, Wojciech Podraza
Introduction: Radiotherapy plays a prominent role in the multidisciplinary treatment of cancers. Despite new irradiation techniques, radiation-induced cardiotoxicity remains a leading cause of morbidity and mortality. Therefore, prognostic indicators of radiotherapy toxicity are essential. This study aimed to investigate the influence of applied radiotherapy on the pulse wave recording and thereby
-
Hypertensive Heart Failure in Asia Pulse Pub Date : 2021-10-11 Helsi Rismiati, Hae-Young Lee
Hypertension (HT) is an important risk factor for heart failure (HF). The prevalence of HT among the HF population is higher in Asia than in other regions around the world. In Asia, HT is the most common cause of HF after ischemic heart disease. Hypertensive HF (HHF) results from structural and functional adaptations of the heart, which lead to left ventricular (LV) hypertrophy (LVH). Hypertensive
-
Sickle Cell Disease-Induced Pulmonary Hypertension: A Review of Pathophysiology, Management, and Current Literature Pulse Pub Date : 2021-09-23 Abu Baker Sheikh, Adeel Nasrullah, Erick Daniel Lopez, Mian Tanveer Ud Din, Shazib Sagheer, Ishan Shah, Nismat Javed, Rahul Shekhar
Sickle cell disease is an inherited hemoglobinopathy leading to the synthesis of hemoglobin S. Hemoglobin S results in the formation of abnormal sickle-shaped erythrocytes that lead to hematologic abnormalities such as hemolytic anemia and increased risks of thrombosis. Another particular problem encountered with the disease is pulmonary hypertension. The objective of this narrative review is to discuss
-
Similar Myocardial Perfusion and Vascular Stiffness in Children and Adolescents with High Lipoprotein (a) Levels, in Comparison with Healthy Controls Pulse Pub Date : 2021-09-10 Kyriaki Papadopoulou-Legbelou, Areti Triantafyllou, Olga Vampertzi, Nikolaos Koletsos, Stella Douma, Efimia Papadopoulou-Alataki
Background and Aims: This study investigated the possible correlation between elevated lipoprotein (a) (Lp(a)) levels and early vascular aging biomarkers in healthy children and adolescents. Methods: Twenty-seven healthy children/adolescents, mean age 9.9 ± 3.7 years, with high Lp(a) levels without other lipid abnormalities and 27 age- and sex-matched controls with normal Lp(a) levels, were included
-
Large Artery Stiffness: A Companion to the 2015 AHA Science Statement on Arterial Stiffness Pulse Pub Date : 2021-08-19 Jimena Rey-García, Raymond R. Townsend
Large artery stiffness (LAS) has proven to be an independent risk factor for cardiovascular disease and mortality. Nevertheless, the position of current hypertension guidelines regarding the usefulness of assessing LAS differs across different continents. In general, European Guidelines recognize pulse wave velocity (PWV) as a marker of target organ damage but do not recommend its systematic use in
-
Converting and Standardizing Various Measures of Arterial Stiffness to Pulse Wave Velocity Pulse Pub Date : 2021-08-12 Taha Alhalimi, Jisok Lim, Drew Gourley, Hirofumi Tanaka
Background: A variety of arterial stiffness measures have been used to assess the impacts of disease states and various interventions without clear consensus among them. One of the primary problems faced by investigators conducting systematic reviews and meta-analyses is the lack of standardized methodology with a same unit to evaluate and compare investigations using different arterial stiffness measures
-
Cold Pressor Test Influences the Cardio-Ankle Vascular Index in Healthy Overweight Young Adults Pulse Pub Date : 2021-08-05 Supaporn Kulthinee, Nitirut Nernpermpisooth, Montatip Poomvanicha, Jidapa Satiphop, Thizanamadee Chuang-ngu, Napaporn Kaleeluan, Kittisak Thawnashom, Anuchit Manin, Rosarin Kongchan, Kingkarn Yinmaroeng, Peerapong Kitipawong, Phatiwat Chotimol
Objective: The cold pressor test (CPT) has been shown a potential sympathoexcitatory stimulus which increases aortic pulse wave velocity and the aortic augmentation index, suggesting that noninvasively, arterial stiffness parameters are altered by the CPT. The cardio-ankle vascular index (CAVI) is widely used for reflecting arterial stiffness, and the ankle-brachial index (ABI) for evaluating peripheral
-
Gender-Related Differences in Hypertrophic Cardiomyopathy: A Systematic Review and Meta-Analysis Pulse Pub Date : 2021-08-02 Angkawipa Trongtorsak, Natchaya Polpichai, Sittinun Thangjui, Jakrin Kewcharoen, Ratdanai Yodsuwan, Amrit Devkota, Harvey J. Friedman, Alfonso Q. Estrada
Background: Gender-related differences in phenotypic expression and outcomes have been established in many cardiac conditions; however, the impact of gender in hypertrophic cardiomyopathy (HCM) remains unclear. We conducted a systematic review and meta-analysis to assess the differences in clinical outcomes between female and male HCM patients. Methods: We searched MEDLINE and EMBASE from inception
-
The Association of Cardio-Ankle Vascular Index and Ankle-Brachial Index in Patients with Peripheral Arterial Disease Pulse Pub Date : 2021-07-07 Taichiro Hayase
Introduction: The cardio-ankle vascular index (CAVI) is a well-known index to evaluate arterial stiffness and predict cardiovascular risk. Methods: We investigated whether CAVI can predict severity and extent of peripheral arterial disease. This study was a single-center, retrospective, observational study approved by the Ethics Committee of Yokohama Shintoshi Neurosurgical Hospital. A total of 96
-
Analysis of 200,000 Exome-Sequenced UK Biobank Subjects Implicates Genes Involved in Increased and Decreased Risk of Hypertension Pulse Pub Date : 2021-07-05 David Curtis
Background: Previous analyses have identified common variants along with some specific genes and rare variants which are associated with risk of hypertension, but much remains to be discovered. Methods and Results: Exome-sequenced UK Biobank participants were phenotyped based on having a diagnosis of hypertension or taking anti-hypertensive medication to produce a sample of 66,123 cases and 134,504
-
The Pulse of Asia 2021 Seoul Pulse Pub Date : 2021-06-30 Ki-Chul Sung, Jong-Won Ha, Hae-Young Lee
Pulse 2021;9:0–0
-
-
-
Cardiovascular Sequelae and Genetics of Familial Mediterranean Fever: A Literature Review Pulse Pub Date : 2021-06-03 Jahanzeb Malik, Asma Shabbir, Atif Nazir
Introduction: Familial Mediterranean fever (FMF) is an autoinflammatory fever syndrome distinguished by recurrent attacks of spontaneous peritonitis, pleuritis, fever, and arthritis. It is specifically seen in the ethnic groups of Mediterranean origin, but sporadic cases have been reported in Eastern Europe and America due to migrations. There is a number of cardiac manifestations associated with FMF
-
From Heartbreak to Heart Disease: A Narrative Review on Depression as an Adjunct to Cardiovascular Disease Pulse Pub Date : 2021-05-31 Jahanzeb Malik, Hamid Sharif Khan, Faizan Younus, Muhammad Shoaib
Patients with cardiovascular disease (CVD) commonly have subclinical depression and are often delayed in their diagnosis. Literature suggests an increased association of depression and adverse cardiovascular events like myocardial infarction and heart failure. Prevalence of depression in developed countries is approximately 16.6%, and it confers higher cardiovascular mortality even after attrition
-
The Hidden Diagnostic Information of the Heart Rhythm Revealed by Entropy Proportions Pulse Pub Date : 2021-05-27 Alberto Avolio
Pulse
-
Application of a Diagnostic Methodology of Cardiac Systems Based on the Proportions of Entropy in Normal Patients and with Different Pathologies Pulse Pub Date : 2021-05-12 Javier Rodríguez, Signed Prieto, Elveny Laguado, Frank Pernett, Magda Villamizar, Edinson Olivella, Fredy Angarita, Giovanni de la Cruz, Carlos Morales, Mónica Castro
Introduction: Dynamical systems theory, probability, and entropy were the substrate for the development of the diagnostic and predictive methodology of adult heart dynamics. Objective: To apply a previously developed methodology from dynamical systems, probability, and entropy in both normal and pathological subjects. Methods: Electrocardiographic records were selected from 30 healthy subjects and
-
Circulating Serum Magnesium and the Risk of Venous Thromboembolism in Men: A Long-Term Prospective Cohort Study Pulse Pub Date : 2021-04-13 Setor K. Kunutsor, Jari A. Laukkanen
Background and Objective: Serum magnesium, an essential trace element involved in processes that regulate cardiovascular function, has been linked to the risk of atherosclerotic cardiovascular disease. However, the potential association between serum magnesium and venous thromboembolism (VTE) has not been previously investigated. We aimed to assess the prospective association of serum magnesium with
-
Uric Acid-to-Albumin Ratio: A Novel Marker for the Extent of Coronary Artery Disease in Patients with Non-ST-Elevated Myocardial Infarction Pulse Pub Date : 2021-03-04 Ender Özgün Çakmak, Emrah Bayam, Mehmet Çelik, Muzaffer Kahyaoğlu, Kıvanç Eren, Elmin Imanov, Ali Karagöz, İbrahim Akın İzgi
Objective: This research aimed to investigate the predictive value of the uric acid-to-serum albumin ratio (UAR) in establishing the severity and extent of coronary artery disease (CAD) with non-ST segment elevation myocardial infarction (NSTEMI) patients. Methods: A total of 402 patients (mean age 63.5 ± 11.6 years) were included in this retrospectively designed study. We compared Synergy between
-
Usefulness of Stress-Derived E/e’ Ratio in Asymptomatic Hypertensive Patients Pulse Pub Date : 2020-11-25 Ragab A. Mahfouz, Mohammed Abdelhamed, Islam Galal, Moataz Elsanan
Purpose: We sought to investigate the usefulness of stress echocardiography-derived E/e’ in predicting subclinical atherosclerosis in asymptomatic hypertensive patients. Materials and Methods: 71 newly diagnosed untreated hypertensive patients (48 ± 13 years, 65% males) and 30 age- and sex-matched healthy controls were recruited. Resting and exercise echocardiography was performed to assess resting
-
Publisher's Note Pulse Pub Date : 2020-07-30 J.B. Park, Ji-Guang Wang, Jeong Bae Park, Kazuomi Kario, Jongmin John Lee, Akira Yamashina, Alberto Avolio, Shigeo Horinaka, Chen-Huan Chen, Hirofumi Tomiyama, Hongyu Wang, Raymond Townsend, James Sharman, Jun Tao, Ernst R. Rietzschel, Carmel McEniery, Kwang-il Kim, Yuhei Kawano, Xiongjing Jiang, Jong-Won Ha, Julio Chirinos, Abdul Rashid Rahman, Fabio Angeli, Walter Abhayaratna, Kee-Sik Kim, Jae-Ryong
Pulse
-
-
The Role of the Platelet/Lymphocyte Ratio and Neutrophil/Lymphocyte Ratio in Predicting High-Risk Heart Score in Patients Admitted with Non-ST Elevation Acute Coronary Syndrome Pulse Pub Date : 2020-01-01 Elshaimaa Seaoud, Ahmed Abdel Hakim Abdelaal Mohamed, Moataz A. Elkot
Background: For cardiologists, management of acute chest pain continues to be a challenge. Physicians struggle to avoid unnecessary admissions and at the same time not to miss high-risk patients needing urgent intervention. Therefore, diagnostic strategies focus on identifying patients in whom an acute coronary syndrome can be safely ruled out based on findings from history, physical examination, and
-
Blood Pressure Variability and Atrial Fibrillation in Patients with Acute ST Segment Elevation Myocardial Infarction: The Relation with Left Atrial Electromechanical Delay – A 1-Year Follow-Up Study Pulse Pub Date : 2020-01-01 Ragab A. Mahfouz, Mohamed El-Shetry, Abdelfattah Frere, Mohamed Safwat
Purpose: To investigate the association between 24-h blood pressure variability (BPV) and atrial electromechanical delay (EMD) in patients with ST segment elevation myocardial infarction (STEMI) who developed new-onset atrial fibrillation (NOAF). Materials and Methods: A total of 175 STEMI patients (age 56.6 ± 10.5 years) who underwent primary percutaneous coronary intervention were subjected to in-hospital
-
Aortic Pulse Wave Velocity, Ankle-Brachial Index, and Malondialdehyde in Older Adults with or without Metabolic Syndrome Pulse Pub Date : 2020-01-01 Ruchada Sri-amad, Nawiya Huipao, Piyapong Prasertsri, Thapanee Roengrit
Metabolic syndrome is an important health problem associated with both subclinical atherosclerosis and an increased risk of cardiovascular disease and it leads to an elevated total mortality. Aortic pulse wave velocity (aPWV) is widely used for noninvasive assessment of arterial stiffness. Ankle-brachial index (ABI) predicts peripheral arterial disease (PAD) of the lower extremities. In addition, malondialdehyde
-
The Role of Heart Rate Variability and Fragmented QRS for Determination of Subclinical Cardiac Involvement in Beta-Thalassemia Major Pulse Pub Date : 2020-01-01 Mozhgan Parsaee, Amir Farjam Fazelifar, Elham Ansaripour, Azita Azarkeyvan, Behshid Ghadrdoost, Ashraf Charmizadeh, Mohaddeseh Behjati
Background: Iron accumulation leads to increased susceptibility to cardiovascular diseases in thalassemia major (TM) patients. Depressed heart rate variability (HRV) and development of arrhythmia are among the manifestations of subclinical cardiac involvement in TM cases. Determination of subclinical cardiac involvement is essential for preventive measures. Thus, we aimed to evaluate the best method
-
Clinical Classification of Arrhythmogenic Right Ventricular Cardiomyopathy Pulse Pub Date : 2020-01-01 Yulia Lutokhina, Olga Blagova, Alexander Nedostup, Svetlana Alexandrova, Anna Shestak, Elena Zaklyazminskaya
Introduction: Commonly accepted clinical classification of arrhythmogenic right ventricular cardiomyopathy (ARVC) is still not developed. Objective: To study the clinical forms of ARVC. Methods: Fifty-four patients (38.7 ± 14.1 years, 42.6% men) with ARVC. Follow-up period: 21 (6–60) months. All patients underwent electrocardiography, 24 h-Holter monitoring, echocardiography, and DNA diagnostic. Magnetic
-
Insight into Atrial Fibrillation in LVAD Patients: From Clinical Implications to Prognosis Pulse Pub Date : 2020-01-01 Nicolò Sisti, Giulia Elena Mandoli, Carlotta Sciaccaluga, Serafina Valente, Sergio Mondillo, Matteo Cameli
The use of left ventricular assist devices (LVADs), whether for destination therapy or bridge to transplantation, has gained increasing validation in recent years in patients with advanced heart failure. Arrhythmias can be the most challenging variables in the management of such patients but the main attention has always been focused on ventricular arrhythmias given the detrimental impact on mortality
-
Resting Left Ventricular Dyssynchrony and Mechanical Reserve in Asymptomatic Normotensive Subjects with Early Type 2 Diabetes Mellitus Pulse Pub Date : 2020-01-01 Ragab A. Mahfouz, Elshaimaa A. Seaoud, Radwa A. Elbelbesy, Islam E. Shehata
Background: Most diabetic patients have silent ischemia and cardiac dysfunction that is usually observed in the late phase of the disease when it becomes clinically obvious. We hypothesized that left ventricular dyssynchrony (LVdys) (or dispersion) is an early marker of myocardial involvement in asymptomatic early type 2 diabetes mellitus (T2DM) patients. Therefore, we aimed to detect early markers
-
Blood Pressure during Blood Collection and the Implication for Absolute Cardiovascular Risk Assessment Pulse Pub Date : 2020-01-01 Niamh Chapman, Dean S Picone, Rachel E. Climie, Martin G. Schultz, Mark R. Nelson, James E. Sharman
Background: Blood collection and blood pressure (BP) measurements are routinely performed during the same consultation to assess absolute cardiovascular disease (CVD) risk. This study aimed to determine the effect of blood collection on BP and subsequent calculation of the absolute CVD risk. Methods: Forty-five participants aged 58 ± 9 years (53% male) had systolic BP (SBP) measured using clinical
-
-
The Effect of Head-Out Aquatic Exercise on Arterial Stiffness in Middle-Aged and Elderly People Pulse Pub Date : 2019-01-01 Marina Fukuie, Takayuki Yamabe, Yosuke Nomura, Tatsuya Hashitomi, Seiji Maeda, Jun Sugawara
Aquatic exercise is ideal for older adults because it mitigates weight-bearing stress. However, the effect of head-out aquatic exercise on arterial stiffness, a strong future cardiovascular disease (CVD) risk, remains unclear. We determined whether head-out aquatic exercise would mitigate arterial stiffness in middle-aged and elderly people. In 25 middle-aged and older people (9 men, mean age 64 ±
-
Vascular Structure and Inflammation in a South African Population: The SABPA Study Pulse Pub Date : 2019-01-01 Carla Swart, Leandi Lammertyn, Paul I. Welsh, Shani Botha-Le Roux
Background and Objective: Inflammation plays a role in the early onset of cardiovascular disease. However, longitudinal studies on this topic, especially in South African populations, are scant. We explored whether early changes in vascular structure are associated with changes in inflammation. Methods: We investigated 303 South African teachers aged 20–65 years at two intervals, three years apart
-
Pseudomyxomaperitonei: A Rare Clinical Entity - A Case Report Pulse Pub Date : 2018-10-19 MF Hossain, MD Hossain, M Begum, AMO Shamsi
Pseudomyxomaperitonei (PMP) is a rare disease characterized by presence of gelatinous ascites and mucinous implants on the peritoneum and omentum. We report the case of a 58 years old woman with primary tumour of the appendix and secondary involvement of other structures & organs of abdominal cavity. Aim of this case report is to create awareness among the clinicians regarding this uncommon disease
-
Obesity, The Single Most Important Risk Factor for OSA: A Case Report Pulse Pub Date : 2018-10-19 SMAA Mamun
Obstructive sleep apnea (OSA) is characterized by repetitive airflow reduction caused by collapse of the upper airway during sleep in addition to daytime sleepiness, clinical symptoms include fatigue, insomnia, and snoring. The condition is associated with adverse clinical outcomes, including cardiovascular disease, hypertension, cognitive impairment, and metabolic abnormalities.1 Among the risk factors
-
Laboratory Diagnostic Options and Challenges for Chikungunya Viruses Pulse Pub Date : 2018-10-19 MM Rahman
Background: Chikungunya infection is a Aedes mosquito transmitted viral disease caused by Chikungunya virus (CHIKV), a member of the Alphavirus genus. It is an important human pathogen that causes a syndrome characterized by fever, chills, headache and severe joint pain usually of the smaller joints, with or without swelling. Though the disease is almost self-limiting, during the recent outbreak CHIKV
-
Anterior Mediastinal Teratoma- A Rare Variety Pulse Pub Date : 2018-10-19 SMAZN Palash, MD Hossain, TMNS Khan, T Meher, MK Hasan, SI Khan, N Ahmed, S Ahmed, MZ Haider
Case Report A 16-year-old non-diabetic, normotensive boy came to Emergency Room of Apollo Hospitals with the complaints of sudden severe right upper abdominal pain radiating to the chest associated with shortness of breath for 1 day. He has no history of cough, hemoptysis, heaviness of chest, fever anorexia, weight loss. After having treatment in local hospital with loading dose of aspirin he was brought
-
Left Atrial Myxoma with Mild Left Ventricular Dysfunction— A Case Report Pulse Pub Date : 2018-10-19 T Meher, SMAZN Palash, MK Hasan, TMNS Khan, NM Zahangir, MZ Haider, SI Khan, CK Devnath, N Ahmed, S Ahmed
29 Pulse Volume 1
-
Surgical Management of Large Mediastinal Masses–12 Years’ Experience in Apollo Hospitals Dhaka Pulse Pub Date : 2018-10-19 NM Zahangir, MK Hasan, RK Basak, T Meher, NS Alam, MN Hossain, A Khan, N Ahmed, S Ahmed, MZ Haider
12 Pulse Volume 1
-
Anti-Phospholipid Antibody Syndrome with Subdural Hematoma: A Case Report Pulse Pub Date : 2018-10-19 MN Uddin, AKMB Karim, N Akter, M Ahmed, M Orin, SA Tanni, M Asaduzzaman, MA Joarder, AJM Saleh, S Ahsan, SM Jahangir, MJ Chandy
Antiphospholipid antibody syndrome (APS) also known as anticardiolipin antibody syndrome, lupus anticoagulant syndrome, or Hughes syndrome was first described by Hughes et al1 as a condition characterized by propensity for arterial/venous thrombosis, recurrent fetal wastage and thrombocytopenia. The presence of an antiphospholipid antibody can be documented by a solid phase serum assay of anticardiolipin
-
Simultaneous Detection and Differentiation of Chikungunya Virus and Dengue Virus in Blood at Clinical Presentation by Real Time RT-PCR Pulse Pub Date : 2018-10-19 MM Rahman, R Rahim, AH Rasel, AS Murad
Background: Chikungunya viral infection in Bangladesh has marked 2017 summer with unprecedented magnitude for the first time. Chikungunya virus (CHIKV) and Dengue virus (DENV) are arboviruses that share the same Aedes mosquito vectors and thus overlap in their endemic areas.These two viruses cause similar clinical presentations, especially in the initial stages of infection. Because the outcomes and
-
A Case of Neurofibromatosis type 1 with Moya Moya Disease Pulse Pub Date : 2018-10-19 SJ Bhuiyan
A 5 years old boy with multiple cafe au lait spots came with intermittent weakness of the right side of the body and seizures. The child had global developmental delay. His MRI and MRA showed thickening of the optic nerves, abnormal signal in multiple areas of the brain with non-visuation of the left middle cerebral artery. The child was diagnosed to have neurofibromatosis type 1 with seizures with
-
A Case of Mollarets Meningitis In Apollo Hospitals Dhaka Pulse Pub Date : 2018-10-19 AA Bhuiyan, KM Rahman, MJ Alam
Mollarets Meningitis is defined as a benign recurrent aseptic meningitis characterized by more than three episodes of fever, headache, meningeal irritation lasting typically 3-5 days. It has spontaneous recovery without any residual neurological deficit. Mollaret in 1944 described this extremely rare form of self-limiting aseptic recurrent benign meningitis. Here we present the report of a patient