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Editorial commentary on AHA scientific statement on meditation and cardiovascular risk reduction. J. Am. Soc. Hypertens. Pub Date : 2018-12-07 Robert H Schneider,Jeremy Z Fields,John W Salerno
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Clinical value of plasma renin activity and aldosterone concentration in the evaluation of secondary hypertension, a case of reninoma. J. Am. Soc. Hypertens. Pub Date : 2018-09-18 Musab S Hommos,Gary L Schwartz
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2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J. Am. Soc. Hypertens. Pub Date : 2018-09-17 Paul K Whelton,Robert M Carey,Wilbert S Aronow,Donald E Casey,Karen J Collins,Cheryl Dennison Himmelfarb,Sondra M DePalma,Samuel Gidding,Kenneth A Jamerson,Daniel W Jones,Eric J MacLaughlin,Paul Muntner,Bruce Ovbiagele,Sidney C Smith,Crystal C Spencer,Randall S Stafford,Sandra J Taler,Randal J Thomas,Kim A Williams,Jeff D Williamson,Jackson T Wright
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Commentary: Postmicturition syndrome: a neglected syndrome dangerous for the bladder and the heart. J. Am. Soc. Hypertens. Pub Date : 2018-08-06 Oksana Hamidi,Todd B Nippoldt
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Postmicturition syndrome: a neglected syndrome dangerous for the bladder and the heart. J. Am. Soc. Hypertens. Pub Date : 2018-07-01 Ilaria Jane Romano,Francesco Gentile,Antonio Lippolis
Postmicturition syndrome refers to symptoms caused by overdistension of the bladder or micturition. Bladder paraganglioma is a rare neuroendocrine neoplasm, which arises from the chromaffin tissue of the sympathetic nervous system embedded in the muscle layer of the bladder wall. Clinical presentation of catecholamine-secreting paragangliomas may mimic that of hyperfunctioning adrenal pheochromocytoma
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Aerobic training reduces blood pressure and waist circumference and increases HDL-c in metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials. J. Am. Soc. Hypertens. Pub Date : 2018-06-28 Ítalo Ribeiro Lemes,Bruna Camilo Turi-Lynch,Iván Cavero-Redondo,Stephanie Nogueira Linares,Henrique Luiz Monteiro
The objective of this study is to estimate the effect of aerobic training (AT) on metabolic syndrome (MetS) outcomes. The Medline, EMBASE, SPORTDiscus, The Cochrane Library, and PEDro databases were searched from inception to May 2017. Two independent reviewers selected the studies and assessed their quality and data. The pooled mean differences between intervention groups and the control group were
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Corrigendum to "Role of angiotensin II type 2 receptor during electrophysiological remodeling of left ventricular hypertrophic myocardium in spontaneously hypertensive rats" Journal of the American Society of Hypertension, January 2018, Volume 12, Issue 1, Pages 58-65. J. Am. Soc. Hypertens. Pub Date : 2018-06-23 Ying Xiao,Wei-Qing Long,Kai-Pan Guan,Ming Long,Gui-Hua Lu,Zhi-Bin Huang
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Findings relevant to the QRS wave in the resting electrocardiogram are associated with circulating concentrations of high-sensitivity cardiac troponin I in the general population. J. Am. Soc. Hypertens. Pub Date : 2018-06-11 Tomonori Sugiura,Yasuaki Dohi,Hiroyuki Takase,Satoshi Fujii,Nobuyuki Ohte
Myocardial damage could develop asymptomatically through nonischemic mechanisms such as cardiac overload. This study investigated possible associations between electrocardiogram (ECG) findings relevant to the QRS wave and high-sensitivity cardiac troponin I (hs-cTnI) in the general population. Subjects undergoing their annual health checkup were enrolled in the study (n = 1258). ECG features relevant
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Diastolic blood pressure and risk profile in renal and cardiovascular diseases. Results from the SPRINT trial. J. Am. Soc. Hypertens. Pub Date : 2018-05-29 Rita Del Pinto,Davide Pietropaoli,Claudio Ferri
The Systolic Blood Pressure Intervention Trial (SPRINT) trial demonstrated the efficacy and safety of targeting a systolic blood pressure of <120 mmHg compared to <140 mmHg in selected hypertensive patients. Some evidence, however, suggests a J-curve for; diastolic blood pressure (DBP) particularly in subjects with cardiovascular (CV) and chronic kidney disease. We evaluated the risk of events in SPRINT
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The cardiovascular health score and the volume of carotid body in computed tomography angiography in patients with arterial hypertension. J. Am. Soc. Hypertens. Pub Date : 2018-05-23 Przemysław Jaźwiec,Paweł Gać,Małgorzata Poręba,Małgorzata Sobieszczańska,Grzegorz Mazur,Rafał Poręba
The cardiovascular health (CVH) score constitutes a reliable and measurable indicator of CVH proposed by the American Heart Association (AHA) calculated based on seven fundamental parameters, that is, smoking, body mass index, physical activity, healthy diet score, blood pressure, blood cholesterol, and fasting plasma glucose. The size and activity of carotid body (CB) play an important role in the
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Balloon angioplasty of renal artery stenosis due to Takayasu arteritis in a 2-year-old child. J. Am. Soc. Hypertens. Pub Date : 2018-05-23 Alimujiang Abudoureyimu,Xingwei He,Jiangtao Yan,Chang Xu,Liru Qiu,Hesong Zeng
The aim of this report is to demonstrate a 2-year-2-month-old child who presented with a history of malignant hypertension. He was made the diagnosis of Takayasu arteritis by laboratory tests and angiography; we initiated a treatment with sequential balloon predilation. The patient's blood pressure improved dramatically, and patency of renal artery was demonstrated with renal arteriography over 8 months
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Ambulatory hypertension in a pediatric cohort of sickle cell disease. J. Am. Soc. Hypertens. Pub Date : 2018-05-05 Divya G Moodalbail,Bonita Falkner,Scott W Keith,Robert S Mathias,Carlos E Araya,Joshua J Zaritsky,Marie J Stuart
Hypertension is an established risk factor for subsequent cardiovascular and renal disease in children as well as adults. Sickle cell disease (SCD) is a genetic disorder associated with chronic hemolytic anemia with the major manifestation of vaso-occlusive crises. Although this disease entity involves most organ systems causing vascular and pulmonary injury, little is known about blood pressure (BP)
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Effects on repetitive 24-hour ambulatory blood pressure in subjects with type II diabetes randomized to liraglutide or glimepiride treatment both in combination with metformin: a randomized open parallel-group study. J. Am. Soc. Hypertens. Pub Date : 2018-03-20 Johan Jendle,Xin Fang,Yang Cao,Leif Bojö,Bo K Nilsson,Fredric Hedberg,Irene Santos-Pardo,Thomas Nyström
In this post hoc study, we aimed to investigate liraglutide treatment on repetitive 24-hour blood pressure (BP) in patients with type II diabetes. Sixty-two individuals with type II diabetes (45 males) were randomized to 1.8 mg liraglutide once daily or 4 mg glimepiride together with 1 g metformin twice daily. Ambulatory 24-hour systolic and diastolic blood pressure (sBP/dBP) was repetitively measured
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2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults. A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J. Am. Soc. Hypertens. Pub Date : 2018-02-06 Robert D Brook,Sanjay Rajagopalan
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Hypertension in postmenopausal women: hemodynamic and therapeutic implications. J. Am. Soc. Hypertens. Pub Date : 2018-01-27 Veronique Regnault,Patrick Lacolley,Michel E Safar
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Latest guidelines for hypertension: adopt and adapt. J. Am. Soc. Hypertens. Pub Date : 2017-11-18 C Venkata S Ram
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From the President, American Society of Hypertension. J. Am. Soc. Hypertens. Pub Date : 2017-10-22 John D Bisognano,Jan N Basile
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Soluble (pro)renin receptor in preeclampsia and diabetic pregnancies. J. Am. Soc. Hypertens. Pub Date : 2017-10-21 Meryam Sugulle,Harald Heidecke,Ulrike Maschke,Florian Herse,A H Jan Danser,Dominik N Mueller,Anne Cathrine Staff,Ralf Dechend
Women with preexisting or gestational diabetes mellitus have an increased risk for developing preeclampsia. Diabetes and pregnancy are both characterized by very high prorenin levels and renin-angiotensin system activation. Prorenin bound to the (pro)renin receptor has enzymatic activity. We hypothesized that soluble (pro)renin receptor levels are elevated in high-risk pregnancies. Third trimester
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Extreme levels of ambient air pollution adversely impact cardiac and central aortic hemodynamics: the AIRCMD-China study. J. Am. Soc. Hypertens. Pub Date : 2017-10-17 Shuo Liu,Robert D Brook,Wei Huang,Zhongjie Fan,Hongbing Xu,Rongshan Wu,Zhichao Sun,Xiaoyi Zhao,Yanping Ruan,Jianhua Yan,Lixian Sun,Ruijuan Liang,Hui Lian,Dongfeng Gu,Sanjay Rajagopalan
Ambient air pollution is an independent risk factor for cardiovascular diseases. However, the underlying mechanisms have yet to be fully elucidated. We performed a panel study on 65 nonsmoking patients with metabolic syndrome, with four repeated clinical visits between 2012 and 2013 in Beijing, China. Cardiac and central aortic hemodynamic parameters were measured by pulse wave analyses as subendocardial
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Assessing the validity of oscillometric device for blood pressure measurement in a large population-based epidemiologic study. J. Am. Soc. Hypertens. Pub Date : 2017-10-17 Zuo Chen,Xin Wang,Zengwu Wang,Linfeng Zhang,Guang Hao,Ying Dong,Manlu Zhu,Runlin Gao,
To evaluate the accuracy of the Omron HBP-1300, an automatic device for blood pressure (BP) measurement, compared with the standard auscultatory method with a mercury sphygmomanometer, we conducted a large population-based survey. From 2012 to 2015, a total of 500,000 participants were randomly selected from the 262 urban cities and rural counties in China, of them BP was measured three times simultaneously
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Pentoxifylline treatment enhances antihypertensive activity of captopril through hemorheological improvement in spontaneously hypertensive rats during development of arterial hypertension. J. Am. Soc. Hypertens. Pub Date : 2017-10-11 Mark B Plotnikov,Alexander Y Shamanaev,Oleg I Aliev,Anastasia V Sidekhmenova,Anna M Anishchenko,Alexander M Arkhipov
The rheological properties of blood play a significant role in the onset and progression of arterial hypertension. The aim of our work was to evaluate the effect of the angiotensin-converting enzyme inhibitor captopril (20 mg/kg/d), pentoxifylline (PTX; 100 mg/kg/d), and the combination of captopril + PTX (20 + 100 mg/kg/d) on the hemodynamic and hemorheological parameters in spontaneously hypertensive
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Air pollution and arterial hypertension. A new risk factor is in the air. J. Am. Soc. Hypertens. Pub Date : 2017-10-11 Elias Sanidas,Dimitris P Papadopoulos,Harris Grassos,Maria Velliou,Kostas Tsioufis,John Barbetseas,Vasilios Papademetriou
Air pollution is one of the greatest environmental threats and has been implicated for several adverse cardiovascular effects including arterial hypertension (HTN). However, the exact relationship between air pollution exposure and HTN is still unclear. Air contamination provokes oxidative stress, systemic inflammation, and autonomic nervous system imbalance that subsequently induce endothelial dysfunction
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Personal-level exposure to environmental temperature is a superior predictor of endothelial-dependent vasodilatation than outdoor-ambient level. J. Am. Soc. Hypertens. Pub Date : 2017-10-11 Chinedu Ejike,Lu Wang,Mochuan Liu,Wei Wang,Masako Morishita,Robert L Bard,Wei Huang,Jack Harkema,Sanjay Rajagopalan,Robert D Brook
Environmental temperatures influence cardiovascular physiology. However, the majority of time is spent indoors, making outdoor-ambient temperatures inaccurate estimates of true exposures encountered by most individuals. We evaluated in 50 healthy adults the associations between previous 7-day outdoor-ambient (four occasions) and prior 24-hour personal-level (two occasions) environmental temperature
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Prehypertension is real and can be associated with target organ damage. J. Am. Soc. Hypertens. Pub Date : 2017-10-03 Barry J Materson,Manuel Garcia-Estrada,Stephane B Degraff,Richard A Preston
Prehypertension (systolic blood pressure 120-139 or diastolic blood pressure 80-89 mm Hg) confers a risk of progression to hypertension, impairment of cognitive function, increased left ventricular mass, risk of end-stage renal disease, and an association with arteriosclerosis. Recent studies provide data that could support the rationale for treating prehypertensives subjects with antihypertensive
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The relationship between hypertensive disorders in pregnancy and placental maternal and fetal vascular circulation. J. Am. Soc. Hypertens. Pub Date : 2017-10-03 Michal Kovo,Jacob Bar,Letizia Schreiber,Marina Shargorodsky
We examined the impact of chronic hypertension (HTN), gestational HTN, and preeclampsia on placental maternal and fetal vascular circulation. Of the 1047 women who gave birth and underwent a placental histopathologic examination between 2007 and 2013 at Wolfson Medical Center, 140 women were included in the present study: 34 women with preeclampsia, 25 women with chronic HTN, 28 women with gestational
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Effects of chronic hepatitis C infection on arterial stiffness. J. Am. Soc. Hypertens. Pub Date : 2017-09-20 Chang-Hua Chou,Chin-Shan Ho,Wei-Chuan Tsai,Ming-Cheng Wang,Yau-Sheng Tsai,Ju-Yi Chen
Nonalcoholic fatty liver disease (NAFLD) is associated with increased arterial stiffness. Although chronic hepatitis C virus (HCV) infection was shown to be associated with metabolic disorder and chronic inflammation, the effects of chronic HCV infection on arterial stiffness remain unclear. This study recruited 221 patients including 32 normal controls, 72 NAFLD patients, and 117 subjects with HCV
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Increased platelet alpha2B-adrenergic receptor gene expression in well-controlled hypertensives: the effect of arterial stiffness. J. Am. Soc. Hypertens. Pub Date : 2017-09-20 Maria E Marketou,Joanna E Kontaraki,John A Papadakis,George E Vrentzos,Alexandros Patrianakos,Konstantinos Fragkiadakis,Panagiotis Tsiverdis,Dimitris Lempidakis,Gregory Chlouverakis,Panos E Vardas,Fragiskos I Parthenakis
Catecholamines play a major role in atherothrombotic mechanisms in essential hypertension. Alpha2B-adrenergic receptors (α2B-ARs) are implicated in the pathophysiology of platelet aggregation. In this study, we evaluated platelet α2B-AR gene expression levels in patients with well-controlled essential hypertension compared with normal individuals and investigated their association with increased arterial
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Adherence to antihypertensive medications and associations with blood pressure among African Americans with hypertension in the Jackson Heart Study. J. Am. Soc. Hypertens. Pub Date : 2017-09-13 Mark J Butler,Rikki M Tanner,Paul Muntner,Daichi Shimbo,Adam P Bress,Amanda J Shallcross,Mario Sims,Gbenga Ogedegbe,Tanya M Spruill
The purpose of this study was to test the association between a self-report measure of 24-hour adherence to antihypertensive medication and blood pressure (BP) among African Americans. The primary analysis included 3558 Jackson Heart Study participants taking antihypertensive medication who had adherence data for at least one study examination. Nonadherence was defined by self-report of not taking
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The 8-oxo-deoxyguanosine glycosylase increases its migration to mitochondria in compensated cardiac hypertrophy. J. Am. Soc. Hypertens. Pub Date : 2017-09-09 Jorge E Vela-Guajardo,Perla Pérez-Treviño,Irais Rivera-Álvarez,Fabio A González-Mondellini,Julio Altamirano,Noemí García
Cardiac hypertrophy is a compensatory mechanism maladapted because it presents an increase in the oxidative stress which could be associated with the development of the heart failure. A mechanism proposed is by mitochondrial DNA (mtDNA) oxidation, which evolved to a vicious cycle because of the synthesis of proteins encoded in the genome is committed. Therefore, the aim of the present work was to evaluate
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Contribution of backward and forward wave pressures to age-related increases in aortic pressure in a community sample not receiving antihypertensive therapy. J. Am. Soc. Hypertens. Pub Date : 2017-09-09 Bryan Hodson,Gavin R Norton,Imraan Ballim,Pinhas Sareli,Angela J Woodiwiss
Reports on the contribution of aortic forward (Pf) and backward (Pb) wave pressures to age-related increases in central aortic pulse pressure (PPc) have been confounded by the use of participants receiving antihypertensive therapy. We assessed the relative contribution of Pf and Pb to age-related increases in PPc (radial applanation tonometry and SphygmoCor software using an assumed triangular wave
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Postexercise hypotension during different water-based concurrent training intrasession sequences in young women. J. Am. Soc. Hypertens. Pub Date : 2017-09-04 Stephanie Santana Pinto,Daniel Umpierre,Hector Kerchirne Ferreira,Gabriela Neves Nunes,Rodrigo Ferrari,Cristine Lima Alberton
The purpose of the study was to compare the acute effects of water-based resistance-aerobic (RA) and aerobic-resistance (AR) sequences on systolic blood pressure, diastolic blood pressure (DBP), and mean blood pressure (MBP) in young women. Thirteen active women participated in four sessions: (1) exercises familiarization, (2) aquatic maximal test to determine the heart rate (HR) corresponding to the
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Central systolic blood pressure and aortic stiffness response to dietary sodium in young and middle-aged adults. J. Am. Soc. Hypertens. Pub Date : 2017-08-24 Bryce J Muth,Michael S Brian,Julio A Chirinos,Shannon L Lennon,William B Farquhar,David G Edwards
High dietary sodium intake can lead to hypertension and increased incidence of cardiovascular disease. We sought to determine the effect of short-term dietary sodium loading on central blood pressure and arterial stiffness in young (YG; 22-40 years) and middle-aged (MA; 41-60 years) normotensive adults. YG (n = 49; age: 27 ± 1 years) and MA (n = 36; age: 52 ± 1 years) subjects were randomized, in a
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Galectin-3 mediates pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension. J. Am. Soc. Hypertens. Pub Date : 2017-08-23 Hui Luo,Bin Liu,Lin Zhao,Jingni He,Tangzhiming Li,Lihuang Zha,Xiaohui Li,Qiangqiang Qi,Yuwei Liu,Zaixin Yu
Pulmonary vascular adventitia serves as a key regulator of pulmonary vascular remodeling in the pathogenesis of pulmonary arterial hypertension (PAH). Excessive proliferation and differentiation of pulmonary adventitial fibroblasts (PAFs) are proven to be crucial in the pathogenesis of PAH. Galectin-3 (Gal-3) is known as a key fibroblasts activating factor which is involved in the fibrogenesis of several
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Effect of dual compared to no or single renin-angiotensin system blockade on risk of renal replacement therapy or death in predialysis patients: PREPARE-2 study. J. Am. Soc. Hypertens. Pub Date : 2017-08-15 Pauline W M Voskamp,Friedo W Dekker,Merel van Diepen,Ellen K Hoogeveen,
Current guidelines on hypertension treatment in chronic kidney disease (CKD) patients discourage combined angiotensin-converting enzyme inhibitor (ACEi) and angiotensin II receptor blocker (ARB) use due to the risk of an increased kidney function decline. However, dual compared to single renin-angiotensin system (RAS) blockade may have more efficacy with regard to hypertension and proteinuria. Among
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Tumor necrosis factor-α receptor 1 contributes to ethanol-induced vascular reactive oxygen species generation and hypertension. J. Am. Soc. Hypertens. Pub Date : 2017-08-12 Janaina A Simplicio,Natália A Gonzaga,Marcelo A Nakashima,Bruno S De Martinis,Thiago M Cunha,Luis F Tirapelli,Carlos R Tirapelli
We evaluated the contribution of tumor necrosis factor-α receptor 1 (TNFR1) to ethanol-induced hypertension and vascular oxidative stress and the possible role of perivascular adipose tissue (PVAT) in such responses. Male C57BL/6 wild-type (WT) or TNFR1-deficient mice (TNFR1-/-) were treated with ethanol (20% vol/vol) for 12 weeks. Ethanol induced an increase in blood pressure in WT mice and TNFR1-/-
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Visit-to-visit variability of blood pressure. J. Am. Soc. Hypertens. Pub Date : 2017-08-10 John B Kostis
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Interarm blood pressure difference in a post-stroke population. J. Am. Soc. Hypertens. Pub Date : 2017-08-02 Eva Gaynor,Linda Brewer,Lisa Mellon,Patricia Hall,Frances Horgan,Emer Shelley,Eamonn Dolan,Anne Hickey,Kathleen Bennett,David J Williams
An increased interarm systolic blood pressure (SBP) difference of ≥10 mm Hg is associated with increased cardiovascular risk and a difference of ≥15 mm Hg with increased cerebrovascular risk. The stroke population presents a high-risk group for future cardiovascular and cerebrovascular events and therefore estimation of interarm SBP difference as a predictive tool may assist with further secondary
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Comparative efficacy of β-blockers on mortality and cardiovascular outcomes in patients with hypertension: a systematic review and network meta-analysis. J. Am. Soc. Hypertens. Pub Date : 2017-08-02 Yuqing Zhang,Ningling Sun,Xueli Jiang,Yang Xi
The differential efficacy of lipophilic and hydrophilic β-blockers on clinical outcomes has not been investigated. We sought to compare the effects of lipophilic and hydrophilic β-blockers on mortality and cardiovascular outcomes by conducting a comprehensive systematic review and network meta-analysis. MEDLINE/PubMed, EMBASE, and the Cochrane Database were searched for all dates to January 5, 2015
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The effect of empagliflozin on muscle sympathetic nerve activity in patients with type II diabetes mellitus. J. Am. Soc. Hypertens. Pub Date : 2017-08-02 Jens Jordan,Jens Tank,Karsten Heusser,Tim Heise,Christoph Wanner,Martina Heer,Sreeraj Macha,Michaela Mattheus,Søren S Lund,Hans J Woerle,Uli C Broedl
Inhibition of sodium glucose cotransporter 2 with empagliflozin results in caloric loss by increasing urinary glucose excretion and has a mild diuretic effect. Diuretic effects are usually associated with reflex-mediated increases in sympathetic tone, whereas caloric loss is associated with decreased sympathetic tone. In an open-label trial, muscle sympathetic nerve activity (MSNA) (burst frequency
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Celastrol synergizes with oral nifedipine to attenuate hypertension in preeclampsia: a randomized, placebo-controlled, and double blinded trial. J. Am. Soc. Hypertens. Pub Date : 2017-08-02 Sha Xiao,Ming Zhang,Yuan Liang,Deling Wang
Preeclampsia, a disease mainly manifesting as serious hypertension during pregnancy, affects expectant mothers around the globe. Celastrol, a naturally existing triterpenoid, is known to exhibit beneficial effects attenuating cardiovascular symptoms including hypertension. We here assessed the treatment outcome against preeclampsia with a combined use of celastrol and nifedipine. A total of 626 patients