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Estimating Left Ventricular Mass from the Electrocardiogram across the Spectrum of LV Mass from Normal to Increased LV Mass in an Older Age Group Cardiol. Res. Pract. (IF 2.1) Pub Date : 2024-3-11 Simon W. Rabkin, Jeremy C. J. Zhou
Objectives. To examine the relationship of QRS voltages and left ventricular (LV) mass across the spectrum of individuals with different LV mass. Methods. Twenty QRS voltage measurements or combinations were determined in a consecutive series of 159 adults with an ECG and echocardiogram without previous myocardial infarction, left or right bundle branch block, pre-excitation, or electronic pacemaker
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Challenges in Effective Referral of Cardiovascular Diseases in Nepal: A Qualitative Study from Health Workers’ and Patients’ Perspective Cardiol. Res. Pract. (IF 2.1) Pub Date : 2024-3-5 Soniya Shrestha, Rashmi Maharjan, Swornim Bajracharya, Niharika Jha, Sushmita Mali, Bobby Thapa, Punya Shori Suwal, Dipanker Prajapati, Biraj Man Karmacharya, Archana Shrestha
Background. Nepal, currently facing a high burden of noncommunicable diseases (NCDs), including cardiovascular diseases (CVDs), which poses the highest mortality rate in the country, does not seem to have a proper referral strategy. This study explored the wide range of factors and challenges that affect the referral system of CVD cases in Nepal. Methods. In this qualitative study, we conducted face-to-face
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Optimizing Anesthetic Selection in Transcatheter Aortic Valve Replacement: Striking a Delicate Balance between Efficacy and Minimal Intervention Cardiol. Res. Pract. (IF 2.1) Pub Date : 2024-2-29 Kahtan Fadah, Seyed Khalafi, Miller Corey, Jose Sotelo, Ahmed Farag, Tariq Siddiqui, Mehran Abolbashari
Patients with severe calcific native aortic valve stenosis (AS) who require valve replacement have two options, surgical aortic valve replacement (SAVR) or transcatheter aortic valve replacement (TAVR). TAVR was approved in late 2011 for extremely high-risk patients and was subsequently approved for high-risk (2012), intermediate-risk (2016), and low-risk (2019) patients. In 2019, TAVR procedures surpassed
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The Comparison of the Initial TIMI Flow Grade in Acute ST-Elevation Myocardial Infarction Patients Receiving Ticagrelor vs. Clopidogrel before Undergoing Primary Percutaneous Coronary Intervention: A Prospective Cohort Study Cardiol. Res. Pract. (IF 2.1) Pub Date : 2024-2-5 Amin Elahifar, Ali Rafati, Mohammad Javad Alemzadeh-Ansari, Yeganeh Pasebani, Behshad Naghshtabrizi, Younes Mohammadi, Seyed Kianoosh Hosseini
Objective. Primary percutaneous coronary intervention (PCI) is the best treatment for acute ST-elevation myocardial infarction (STEMI). Evidence is in favor of ticagrelor over clopidegrel in STEMI patients regarding the reduction of stent thrombosis risk during and after PCI. We compared initial thrombolysis in myocardial infarction (TIMI) flow in STEMI patients on ticagrelor vs. clopidogrel. Methods
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Relationship between Brain Natriuretic Peptide and Thromboembolic Events in Elderly Patients with Nonvalvular Atrial Fibrillation Cardiol. Res. Pract. (IF 2.1) Pub Date : 2024-1-17 Hongxia Wang, Jiajun Huang, Wenxi Gu, Xiaojiao Hao, Guiru Li, Yumin Yuan, Yingmin Lu
Objective. To investigate the relationship between brain natriuretic peptide (BNP) and thromboembolic events in elderly patients with nonvalvular atrial fibrillation (NVAF). Methods. This is a prospective cohort study, and based on the inclusion and exclusion criteria, 180 elderly patients with NVAF were included. The patients received follow-up appointments in the clinic or by telephone every 6 months
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Global Longitudinal Strain May Be the One that Appropriately Identifies Candidates of ICD Implantation Cardiol. Res. Pract. (IF 2.1) Pub Date : 2024-1-16 Mohammad Hossein Nikoo, Mohammad Zarrabi, Alireza Moaref, Iman Razeghian-Jahromi
Hypertrophic cardiomyopathy (HCM) significantly contributes to an elevated risk of sudden cardiac death. Primary prevention is implemented by using an implantable cardioverter defibrillator (ICD). However, all of the HCM patients do not really need ICD therapy. Providing a superior index for ICD indication compared with the current indices like ejection fraction is essential to differentiate high-risk
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Performance and Physician Experience of INGEVITY+ Active Fixation Leads: Prospective INGEVITY+ Lead Clinical Study in Korea Cardiol. Res. Pract. (IF 2.1) Pub Date : 2024-1-11 Boyoung Joung, Myung Hwan Bae, Il-Young Oh, Hyung-Seob Park, Jaemin Shim, Min Soo Cho, Jung Myung Lee, Eue-Keun Choi, Young Soo Lee
Background. Boston Scientific INGEVITY+ pacing lead (Boston Scientific, Marlborough, MA, USA) has been upgraded to INGEVITY. The performance of the INGEVITY+ pacing lead has not yet been reported. This study aimed to evaluate the short- and long-term safety, effectiveness, and handling experience of INGEVITY+ leads. Methods. Consecutive patients were included from 9 institutions in Korea, where 400
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Guidewire Ablation within the Coronary Venous System for Epicardial or Intramural Ventricular Arrhythmia: A Preclinical Study of Biophysical Characterization Cardiol. Res. Pract. (IF 2.1) Pub Date : 2024-1-4 Fengqi Xuan, Zhongyin Zuo, Jie Zhang, Shibei Zhang, Zichen Liu, Yunfan Meng, Kuo Sun, Yaling Han, Ming Liang, Zulu Wang
Background. Catheter ablation failure poses a clinical challenge for epicardial or intramural ventricular arrhythmia (VA); however, guidewire ablation within the coronary venous system (CVS) may be effective and safe for targeting VAs. Methods. The ex vivo phase included four steps. In step 1, the steam pop incidence rates during guidewire ablation at power settings of 5, 10, 15, 20, and 25 W were
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Safety and Feasibility Using a Fluid-Filled Wire to Avoid Hydrostatic Errors in Physiological Intracoronary Measurements Cardiol. Res. Pract. (IF 2.1) Pub Date : 2024-1-2 Truls Råmunddal, Christian Dworeck, Petronella Torild, Sofie Andréen, Li-Ming Gan, Geir Hirlekar, Dan Ioanes, Anna Myredal, Jacob Odenstedt, Petur Petursson, Tetiana Pylova, Fanny Töpel, Sebastian Völz, Mats Hilmersson, Björn Redfors, Oskar Angerås
Background. Using a fluid-filled wire with a pressure sensor outside the patient compared to a conventional pressure wire may avoid the systematic error introduced by the hydrostatic pressure within the coronary circulation. Aims. To assess the safety and effectiveness of the novel fluid-filled wire, Wirecath (Cavis Technologies, Uppsala, Sweden), as well as its ability to avoid the hydrostatic pressure
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Enhanced External Counterpulsation for Management of Postacute Sequelae of SARS-CoV-2 Associated Microvascular Angina and Fatigue: An Interventional Pilot Study Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-12-27 Eline Wu, Ali Mahdi, Jannike Nickander, Judith Bruchfeld, Linda Mellbin, Kristina Haugaa, Marcus Ståhlberg, Liyew Desta
Background. Postacute sequelae of SARS-CoV-2 infection (PASC) are a novel clinical syndrome characterized in part by endothelial dysfunction. Enhanced external counterpulsation (EECP) produces pulsatile shear stress, which has been associated with improvements in systemic endothelial function. Objective. To explore the effects of EECP on symptom burden, physical capacity, mental health, and health-related
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Relationship between Coronary Artery Calcium Score and Coronary Stenosis Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-12-15 Xinyan Chen, Jianbin Zhao, Qingqing Cai, Rong Chen, Wenhao Wu, Peng Wang, Gaoxing Zhang, Jinhuan Zhen
Background. The coronary artery calcium score (CACS) is commonly employed to quantify the degree of calcification in coronary atherosclerosis. Indeed, increased coronary stenosis severity is associated with a progressive increase in CACS. Objectives. This study sought to explore the association between CACS and coronary stenosis of ≥50% and ≥70%. Methods. We conducted a retrospective analysis of patient
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Comparative Analysis of Hypertension Guidelines: Unveiling Consensus and Discrepancies in Lifestyle Modifications for Blood Pressure Control Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-12-12 Yi Wang, Yanxiang Liu, Lu Liu, Liqiong Hong, Huimin Chen
Background. Hypertension is a major global health concern, and lifestyle modifications have been recommended as first-line treatment for hypertension in many guidelines. However, different guidelines may recommend different types of lifestyle adjustment, and it is unclear which ones are most effective. In this review, we compared hypertension guidelines to identify any differences and/or consensus
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Evaluation of Left Atrial Function in Patients with Paroxysmal Atrial Fibrillation Using Left Atrial Automatic Myocardial Functional Imaging Ultrasonography Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-11-20 Hailan Liu, Lili Chen, Yan Song, Yingying Xu, Chunquan Zhang
Aim. To evaluate volume and strain of the left atrium (LA) in people suffering from paroxysmal atrial fibrillation which is not valvular (NVPAF) using the new technology of left atrial automatic myocardial function imaging (AFILA) and to analyze prognostic factors in patients with NVPAF by follow-up. Methods. Between August 2019 and August 2022, a total of 80 NVPAF patients and 60 normal control patients
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Complications of Implantable Cardioverter Defibrillator and Their Potential Risk Factors in Patients with Hypertrophic Cardiomyopathy Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-11-13 Mohammad Taghi Hedayati Goudarzi, Maryam Moradi, Saeed Abrotan, Mehrdad Saravi, Hoda Shirafkan, Rana Irilouzadian, Hossein Salehi Omran
Background. Hypertrophic cardiomyopathy (HCM) has different complications such as cardiac arrhythmia and sudden cardiac death (SCD). Insertion of an implantable cardioverter defibrillator (ICD) is recommended for HCM patients who are at high risk of SCD and malignant arrhythmias, despite having their own potential complications. Hypothesis. We aimed to investigate the prevalence of different complications
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Prevalence and Risk Factors of Postprocedure Depression in Patients with Atrial Fibrillation after Radiofrequency Ablation Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-11-7 Mingli Du, Tieniu Cheng, Yutong Ye, Yong Wei
Background. Recent studies have shown a bidirectional relationship between atrial fibrillation (AF) and psychological depression. However, little is known about the prevalence of postprocedure depression (PPD) in patients with AF at the time of radiofrequency (RF) ablation. Objective. To describe the prevalence and identify risk factors for PPD. Methods. This was a prospective cohort study, including
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Bachmann’s Bundle Modification in Addition to Circumferential Pulmonary Vein Isolation for Atrial Fibrillation: A Novel Ablation Strategy Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-10-27 Jiaqi Sun, Sanbao Chen, Ming Liang, Qi Zhang, Ping Zhang, Mingyu Sun, Jian Ding, Zhiqing Jin, Yaling Han, Zulu Wang
Background. Bachmann’s bundle (BB) is the main pathway of interatrial connection that could be involved in the development of atrial fibrillation (AF). Based on this hypothesis, we raised a novel ablation strategy, BB modification in addition to circumferential pulmonary vein isolation (CPVI-BB) in patients with AF. Methods. A retrospective cohort of patients with AF who underwent CPVI-BB or CPVI alone
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Retracted: High-Density Lipoprotein Cholesterol in Young Nondiabetic Coronary Heart Disease Patients. Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-10-11 Cardiology Research And Practice
[This retracts the article DOI: 10.1155/2021/2970568.].
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Retracted: Establishment of a Nomogram for Predicting Early Death in Viral Myocarditis. Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-10-11 Cardiology Research And Practice
[This retracts the article DOI: 10.1155/2021/9947034.].
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Serum Galectin-3 Predicts Mortality in Venoarterial Extracorporeal Membrane Oxygenation Patients Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-9-30 Jianlong Zhu, Dehui Guo, Liying Liu, Jing Zhong
Objective. We investigated the potential use of galectin-3 (Gal-3) as a prognostic indicator for patients with cardiogenic shock and developed a predictive mortality model for venoarterial extracorporeal membrane oxygenation (VA-ECMO). Methods. We prospectively studied patients (survivors and nonsurvivors) who received VA-ECMO for cardiogenic shock from 2019 to 2021. We recorded baseline data, Gal-3
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The Effect of Base Theory Educational Intervention on Health-Promoting Lifestyle in Women Susceptible to Cardiovascular Diseases: Application of the Theory of Planned Behavior Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-7-21 Peyman Izadpanah, Negin Saadat, Bahareh Kabiri, Fatemeh Mohammadkhah, Pooyan Afzali Harsini, Ali Khani Jeihooni
Background. Cardiovascular diseases are the second leading cause of mortality, disability, and reduced productivity in women over 40 years and the first cause of mortality in women over 60 years. Therefore, the present study aimed to determine the effect of educational intervention based on theory of planned behavior (TPB) on health-promoting lifestyle in women susceptible to cardiovascular diseases
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Long-Term Outcomes of Bovine versus Porcine Mitral Valve Replacement: A Multicenter Analysis Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-6-30 M. Broadwin, N. Ramkumar, D. J. Malenka, R. D. Quinn, C. S. Ross, F. Hirashima, J. D. Klemperer, R. S. Kramer, G. L. Sardella, B. Westbrook, A. W. Discipio, A. Iribarne, M. P. Robich
Introduction. Recent national guidelines recommending mitral valve replacement (MVR) for severe secondary mitral regurgitation have resulted in an increased utilization of mitral bioprosthesis. There is a paucity of data on how longitudinal clinical outcomes vary by prosthesis type. We examined long-term survival and risk of reoperation between patients having bovine vs. porcine MVR. Study Design.
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Outcomes of Combined Heart-Kidney Transplantation in Older Recipients Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-6-24 Curry Sherard, Vineeth Sama, Jennie H. Kwon, Khaled Shorbaji, Lauren V. Huckaby, Brett A. Welch, Chakradhari Inampudi, Ryan J. Tedford, Arman Kilic
Objectives. The upper limit of recipient age for combined heart-kidney transplantation (HKT) remains controversial. This study evaluated the outcomes of HKT in patients aged ≥65 years. Methods. The United Network of Organ Sharing (UNOS) was used to identify patients undergoing HKT from 2005 to 2021. Patients were stratified by age at transplantation: <65 and ≥ 65 years. The primary outcome was one-year
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Real-World Experience with Cangrelor as Adjuvant to Percutaneous Coronary Intervention: A Single-Centre Observational Study Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-6-16 Troels Thim, Lars Jakobsen, Rebekka Vibjerg Jensen, Nicolaj Støttrup, Ashkan Eftekhari, Erik Lerkevang Grove, Sanne Bøjet Larsen, Jacob Thorsted Sørensen, Steen Carstensen, Sahar Amiri, Karsten Tange Veien, Evald Høj Christiansen, Christian Juhl Terkelsen, Michael Maeng, Steen Dalby Kristensen
Background. Reversible P2Y12 inhibition can be obtained with cangrelor administered intravenously. More experience with cangrelor use in acute PCI with unknown bleeding risk is needed. Objectives. To describe real-world use of cangrelor including patient and procedure characteristics and patient outcomes. Methods. We performed a single-centre, retrospective, and observational study including all patients
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Genetic Testing Enables the Diagnosis of Familial Hypercholesterolemia Underdiagnosed by Clinical Criteria: Analysis of Japanese Early-Onset Coronary Artery Disease Patients Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-4-28 Hiroshi Miyama, Yoshinori Katsumata, Mizuki Momoi, Genki Ichihara, Taishi Fujisawa, Jin Endo, Takashi Kawakami, Masaharu Kataoka, Shinsuke Yuasa, Motoaki Sano, Kazuki Sato, Keiichi Fukuda
Definitive diagnosis of familial hypercholesterolemia (FH) is paramount for the risk management of patients and their relatives. The present study aimed to investigate the frequency of gene variants contributing to low-density lipoprotein cholesterol (LDL-C) metabolism and their clinical relevance in patients with early-onset coronary artery disease (EOCAD). Among 63 consecutive patients with EOCAD
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SFRP4 Reduces Atherosclerosis Plaque Formation in ApoE Deficient Mice Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-4-25 Hua Guan, Ting Liu, Miaomiao Liu, Xue Wang, Tao Shi, Fengwei Guo
Secreted frizzled related protein 4 (SFRP4), a member of the SFRPs family, contributes to a significant function in metabolic and cardiovascular diseases. However, there is not enough evidence to prove the antiatherosclerosis effect of SFRP4 in ApoE knock-out (KO) mice. ApoE KO mice were fed a western diet and injected adenovirus (Ad)-SFRP4 through the tail vein for 12 weeks. Contrasted with the control
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The Efficacy of Drug-Coated Balloon for Acute Coronary Syndrome Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-4-20 Hirokazu Naganawa, Akira Ito, Shinrou Saiki, Daisuke Nishi, Shinichi Takamatsu, Yoshihisa Ito, Takeshi Suzuki
Background. Percutaneous coronary intervention using a drug-eluting stent (DES) is a common therapeutic option for acute coronary syndrome (ACS). However, stent-associated complications, such as bleeding associated with dual antiplatelet therapy, in-stent restenosis, stent thrombosis, and neoatherosclerosis, remain. Drug-coated balloons (DCBs) are expected to reduce stent-associated complications.
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Plasma Levels of Matrix Metalloproteinases 2 and 9 in Patients with Chronic Chagas Heart Disease and Systemic Arterial Hypertension: Correlation with TGF-Beta Plasma Levels Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-4-19 Reinaldo B. Bestetti, Renata Dellalibera-Joviliano, Ellen Rizzi, Giselle F. Bonacio, Milton Faria-Jr, Rosemeire Furlan-Daniel, Suzeley Castro-França
Background. Chronic Chagas heart disease (CCHD) and systemic arterial hypertension (SAH) frequently coexists in areas where Chagas disease is endemic. The effects of the association of both conditions (CCHD-SAH) on the extracellular matrix (ECM) remodeling are unknown. Matrix metalloproteinases (MMP) 2 and 9 are involved in ECM remodeling. The aim of this study was to evaluate MMP 2 and MMP9 in CCHD-SAH
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Exogenous Hydrogen Sulfide Activates PI3K/Akt/eNOS Pathway to Improve Replicative Senescence in Human Umbilical Vein Endothelial Cells Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-4-6 Haiming Niu, Jianwei Li, Hongkai Liang, Guishen Wu, Miaolian Chen
Background. Endothelial cell senescence is one of the key mechanistic factors in the pathogenesis of atherosclerosis. In terms of molecules, the phosphatidylinositol 3-kinase/protein kinase B/endothelial nitric oxide synthase (PI3K/Akt/eNOS) signaling plays an important role in the prevention and control of endothelial cell senescence, while hydrogen sulfide (H2S) improves the induced precocious senescence
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The Effect of High-Intensity Interval Training on Exercise Capacity in Patients with Coronary Artery Disease: A Systematic Review and Meta-Analysis Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-4-3 Siyi Li, Xiankun Chen, Huachen Jiao, Yan Li, Guanghui Pan, Xue Yitao
Background. The optimal exercise prescription for coronary artery disease (CAD) remains under debate. The aim of our meta-analysis is to investigate the efficacy of high-intensity interval training (HIIT) versus moderate-intensity continuous training (MICT) of coronary artery disease patients. Methods. Electronic databases were searched from their inception date until October 23, 2021, and the articles
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A Small Increase in Serum Creatinine within 48 h of Hospital Admission Is an Independent Predictor of In-Hospital Adverse Outcomes in Patients with ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: Findings from the Improving Care for Cardiovascular Disease in the China Project Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-3-28 Jiajia Zhu, Wenxian Liu, Jiang Li, Changsheng Ma, Dong Zhao
Background. Acute kidney injury (AKI) is a common complication of percutaneous coronary intervention (PCI) that has been associated with high morbidity and mortality in patients with STEMI. Acute tubular damage may be reflected by serum creatinine (Scr) values that do not meet the criteria for AKI. Methods. This analysis included 19,424 patients from the Improving Care for Cardiovascular Disease in
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The Impact of Complete Revascularization in Symptomatic Severe Left Ventricular Dysfunction between Coronary Artery Bypass Graft and Percutaneous Coronary Intervention Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-2-28 Hsiu-Yu Fang, Yen-Nan Fang, Yin-Chia Chen, Jiunn-Jye Sheu, Wei-Chieh Lee
Objective. The study aimed to compare the clinical outcomes between the patients receiving coronary artery bypass surgery (CABG) or percutaneous coronary intervention (PCI) for the patients with symptomatic severe left ventricular (LV) dysfunction and coronary artery disease (CAD). Methods. Between February 2007 and February 2020, a total of 745 patients who received coronary artery angiography for
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Valve-Sparing Aortic Root Replacement Technique: Valsalva Graft versus Two Straight Tubular Grafts Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-2-3 Alexander Makkinejad, Bailey Brown, Rana-Armaghan Ahmad, Joanna Hua, Xiaoting Wu, Shinichi Fukuhara, Karen Kim, Himanshu Patel, G. Michael Deeb, Bo Yang
Background. There are many variations in valve-sparing aortic root replacement techniques. Our aim is to determine the impact of the graft on mid-term outcomes: Valsalva graft vs. two straight tubular grafts. Methods. From 2004 to 2020, 332 patients underwent valve-sparing aortic root replacement with either a Valsalva graft (Valsalva group: n = 270) or two straight tubular grafts (two-graft group:
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Quantifying Myocardial Blood Flow and Resistance Using 4D-Flow Cardiac Magnetic Resonance Imaging Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-2-2 Rebecca C. Gosling, Gareth Williams, Abdulaziz Al Baraikan, Samer Alabed, Eylem Levelt, Amrit Chowdhary, Peter P. Swoboda, Ian Halliday, D. Rodney Hose, Julian P. Gunn, John P. Greenwood, Sven Plein, Andrew J. Swift, James M. Wild, Pankaj Garg, Paul D. Morris
Background. Ischaemia with nonobstructive coronary arteries is most commonly caused by coronary microvascular dysfunction but remains difficult to diagnose without invasive testing. Myocardial blood flow (MBF) can be quantified noninvasively on stress perfusion cardiac magnetic resonance (CMR) or positron emission tomography but neither is routinely used in clinical practice due to practical and technical
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Recombinant Adenovirus siRNA Knocking Down the Ndufs4 Gene Alleviates Myocardial Apoptosis Induced by Oxidative Stress Injury Cardiol. Res. Pract. (IF 2.1) Pub Date : 2023-1-27 Beibei Wang, Jinsheng Zhang, Aijun Xu
Oxidative stress results in myocardial cell apoptosis and even life-threatening heart failure in myocardial ischemia-reperfusion injury. Specific blocking of the complex I could reduce cell apoptosis. Ndufs4 is a nuclear-encoded subunit of the mitochondrial complex I and participates in the electron transport chain. In this study, we designed and synthesized siRNA sequences knocking down the rat Ndufs4
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The Primary Alteration of Ventricular Myocardium Conduction: The Significant Determinant of Left Bundle Branch Block Pattern Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-12-20 Ljuba Bacharova, Bayes de Luna
Intraventricular conduction disturbances (IVCD) are currently generally accepted as ECG diagnostic categories. They are characterized by defined QRS complex patterns that reflect the abnormalities in the intraventricular sequence of activation that can be caused by pathology in the His-Purkinje conduction system (HP) or ventricular myocardium. However, the current understanding of the IVCD’s underlying
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Early and Late Mortality Predictors in Patients with Acute Aortic Dissection Type B Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-11-26 Ratko M. Lasica, Jovan P. Perunicic, Dejana R. Popovic, Igor B. Mrdovic, Ross A. Arena, Nebojsa L. Radovanovic, Mina R. Radosavljevic-Radovanovic, Lazar D. Djukanovic, Milika R. Asanin
Background/Aim. Despite technological advances in diagnosis and treatment, in-hospital mortality with acute aortic dissection type B is still about 11%. The purpose of this study was to assess the risk factors for early and long-term adverse outcomes in patients with acute aortic dissection type B treated medically or with conventional open surgery. Methods. The present study included 104 consecutive
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Use of Novel Blunt Dissection Technique for Surgical Unroofing in Myocardial Bridging Patients Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-11-9 Xiangyang Wu, Jie Zhu, Yong Mao, Xinqiang Guan, Xiaofeng He, Qi Ma, Xiaopeng Zhang, Shixiong Wang, Yongnan Li
Background. Myocardial bridging (MB) is a congenital anomaly involving the myocardial tissue encasement of a segment of the coronary artery. The purpose of the present study was to assess safety and efficacy of two surgical methods used for treating MB patients at our institute. Methods. Off-pump MB unroofing was performed in 45 adult patients between January 2016 and December 2021 by traditional surgical
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The Systemic Immune-Inflammation Index May Predict the Coronary Slow Flow Better Than High-Sensitivity C-Reactive Protein in Patients Undergoing Elective Coronary Angiography Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-11-9 Kurtulus Karauzum, Irem Karauzum, Kaan Hanci, Dogus Gokcek, Beyzanur Gunay, Hussain Bakhshian, Tayfun Sahin, Ertan Ural
Background and Objectives. The coronary slow flow (CSF) is an angiographic finding characterized by delayed opacification of nonobstructive epicardial coronary arteries. Chronic inflammation has been suggested to be mainly responsible for the underlying mechanism of CSF. The systemic immune-inflammation index (SII) is a relatively novel inflammation-based biomarker, derived from counts of peripheral
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Atorvastatin Inhibits Ferroptosis of H9C2 Cells by regulatingSMAD7/Hepcidin Expression to Improve Ischemia-Reperfusion Injury Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-11-8 You Peng, Bin Liao, Yan Zhou, Wei Zeng, Zhi-Yu Zeng
Background. Ferroptosis plays a key role in cardiomyopathy. Atorvastatin (ATV) has a protective effect on ischemia-reperfusion (I/R) cardiomyopathy. The purpose of this study is to elucidate the mechanism of ATV in I/R injury. Methods. H9C2 cells and cardiomyopathy rats were induced by hypoxia/reoxygenation (H/R) and I/R to construct in vitro and in vivo models. Cell viability was determined by CCK8
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Prognostic Significance of Percutaneous Coronary Intervention for First Acute Myocardial Infarction with Heart Failure: Five-Year Follow-Up Results Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-11-3 Zichao Cheng, Yuchen Shi, Hongyu Peng, Donghui Zhao, Qian Fan, Jinghua Liu
Objective. The study aimed to investigate the incidence and influencing factors of heart failure after 5 years of percutaneous coronary intervention (PCI) for first acute myocardial infarction. Methods. A total of 1235 patients, diagnosed as acute myocardial infarction and treated with PCI in Beijing Anzhen Hospital, Capital Medical University, from January 1, 2014, to December 31, 2014, were enrolled
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Effect of Lycopene Supplementation on Some Cardiovascular Risk Factors and Markers of Endothelial Function in Iranian Patients with Ischemic Heart Failure: A Randomized Clinical Trial Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-10-28 Bahareh Karimian, Azam Soleimani, Ghasem Mohammadsharifi, Kiyan Heshmat-Ghahdarijani, Laila Rejali, Davood Shafie, Atefeh Amerizadeh, Masoumeh Sadeghi
Aim. This study aimed to explore if supplementary lycopene tablets may help heart failure (HF) patients improve their lipid profile, BP, and the flow-mediated dilation (FMD) index for endothelial function. Methods. Fifty patients with ischemic HF with a reduced ejection fraction (HFrEF) were randomly assigned to one of two groups: the lycopene group which received 25 mg lycopene tablets once a day
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Comparison of Electrocardiogram and QT Interval between Viral Hepatitis Cirrhosis and Alcoholic Cirrhosis Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-10-18 Li-Hong Lu, Xue-Ya Lv, Qi-Ming Wu, Qian Dong, Zhao Wang, Su-Juan Zhang, Li Fu, Qian Wang, Yu-Qing Song
Objective. This study aims to compare the electrocardiogram (ECG) abnormalities and QT interval prolongation in 2,886 patients with viral hepatitis cirrhosis and 643 patients with alcoholic cirrhosis in order to understand the characteristics of ECG in patients with cirrhosis and provide information and evidence for clinical diagnosis and treatment. Methods. The ECG data of patients with viral hepatitis
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Predicting Postoperative Troponin in Patients Undergoing Elective Hip or Knee Arthroplasty: A Comparison of Five Cardiac Risk Prediction Tools Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-10-14 Merih T. Tesfazghi, Anne R. Bass, Noor Al-Hammadi, Scott C. Woller, Scott M. Stevens, Charles S. Eby, Mitchell G. Scott, Lindsey Snyder, Troy S. Wildes, Brian F. Gage
Background. Elderly patients undergoing hip or knee arthroplasty are at a risk for myocardial injury after noncardiac surgery (MINS). We evaluated the ability of five common cardiac risk scores, alone or combined with baseline high-sensitivity cardiac troponin I (hs-cTnI), in predicting MINS and postoperative day 2 (POD2) hs-cTnI levels in patients undergoing elective total hip or knee arthroplasty
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How is Ambulatory Electrocardiogram Predictive of Stroke in Atrial Fibrillation Patients? Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-10-10 Xiuping Zhuo, Meinv Huang
Background. Atrial fibrillation (AF) is a significant stroke risk factor. Further research is needed to clarify whether higher atrial fibrillation burden (AFB) link to the elevated risk of ischemic embolism, and how AF burden could combine with CHA2DS2-VASc score to improve the anticoagulation strategy. We aim to evaluate if the AF burden characterized using 24-hours Holter ECG monitoring is associated
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Serum Zinc Ion Concentration Associated with Coronary Heart Disease: A Systematic Review and Meta-Analysis Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-10-6 Heyu Meng, Jianjun Ruan, Yanqiu Chen, Zhaohan Yan, Xin Meng, Xiangdong Li, Jinsha Liu, Cuiying Mao, Ping Yang
Aim. Coronary heart disease is a major cause of mortality in developed and developing countries. Changes in the trace element concentration in the human body are one of the main reasons for the transition of the human body from a healthy to a diseased state. In this meta-analysis, we have studied the relationship between the reduction in serum zinc ion concentration and coronary heart disease. Methods
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Associations between β-Blocker Therapy at Discharge and Long-Term Follow-Up Outcomes in Patients with Unstable Angina Pectoris Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-9-29 Lei Liu, Xiaosong Ding, Hui Chen, Weiping Li, Hongwei Li
Background. The effects of β-blockers in patients with unstable angina pectoris (UAP) are unclear. We tried to evaluate associations between β-blockers in UAP and long-term outcomes. Methods. We enrolled 5591 UAP patients and divided them into 2 groups based on β-blockers at discharge: 3790 did β-blockers and 1801 did not used them. Propensity score matching at 1 : 1 was performed to select 1786 patients
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The Predictive Value of Epicardial Fat Tissue Volume in the Occurrence and Development of Atrial Fibrillation: A Systematic Review and Meta-Analysis Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-9-29 Qiankun Fan, Yinge Zhan, Mingqi Zheng, Fangfang Ma, Lishuang Ji, Lei Zhang, Gang Liu
Background. Atrial fibrillation (AF) is one of the most common arrhythmias in clinical practice. Although fat is currently considered to be a risk factor for AF and a pathogenic link between epicardial fat tissue (EFT) and AF has been speculated, there are currently few clinical studies and literature data domestically or abroad. Objective. This study conducted a meta-analysis of observational case
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Flow-Mediated Dilatation in the Assessment of Coronary Heart Disease: A Meta-Analysis Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-9-28 Xiaoyong Xiao, Xian Li, Xiaohua Xiao, Jingjing Wang, Dehong Liu, Zhe Deng
Endothelial dysfunction may contribute to the increased morbidity and mortality associated with coronary heart disease (CHD). Flow-mediated dilatation (FMD) is the most popular noninvasive method for vascular endothelial function evaluation. This meta-analysis aimed to investigate the association between FMD and CHD. We searched the publications listed in the PubMed, Web of Science, Scopus, and Embase
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Comparison of 6-Month and Prolonged Dual Antiplatelet Therapy after Percutaneous Coronary Intervention with Biodegradable Polymer Everolimus-Eluting Stent Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-9-28 Yong-Hoon Yoon, Gyung-Min Park, Jae-Hyung Roh, Sung-Ho Her, Seong-Hoon Lim, Tae Soo Kang, Seung Jin Lee, Jang-Whan Bae, WoongGil Choi, Yong-Mo Yang, Junghee Kim, Yu Jeong Choi, Si Wan Choi, Jae-Hwan Lee
Background. The optimal duration of dual antiplatelet therapy (DAPT) after biodegradable-polymer (BP) everolimus-eluting stent (EES) implantation remains uncertain. Methods. This study analyzed 793 patients who underwent percutaneous coronary intervention (PCI) with BP-EES in 10 cardiovascular centers in Korea between July 2016 and January 2018. Using the prescription data at 6 months post-PCI, we
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Mitral Annular Plane Systolic Excursion (MAPSE) as a Predictor of Atrial Fibrillation Recurrence in Patients after Pulmonary Vein Isolation Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-9-27 Jan Alatic, David Suran, Damijan Vokac, Franjo Husam Naji
Introduction. Catheter ablation (CA) with pulmonary vein isolation (PVI) has become widely used in the past years for the treatment of atrial fibrillation (AF). Mitral annular plane systolic excursion (MAPSE) is the parameter that measures left ventricular longitudinal function, and it appears to be a good early marker of LV dysfunction. It is practically independent of poor image quality. The aim
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Expression of TLR4 Is Upregulated in Patients with Sporadic Acute Stanford Type A Aortic Dissection Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-9-23 Xinyi Liu, Ai Zhang, Nianguo Dong, Zhiwen Wang
Sporadic acute Stanford type A aortic dissection (TAAD) is a serious condition that requires urgent treatment to avoid catastrophic consequences. The purpose of the present study was to explore, firstly, whether TLR4-regulated immune signalling molecules were activated in TAAD patients and, secondly, whether TLR4-regulated inflammatory products interleukin-1β (IL-1β) and CC chemokine ligand 5 (CCL5)
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Sex Disparity in Characteristics, Management, and In-Hospital Outcomes of Patients with ST-Segment Elevated Myocardial Infarction: Insights from Henan STEMI Registry Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-09-05 Shan Wang, You Zhang, Qianqian Cheng, Datun Qi, Xianpei Wang, Zhongyu Zhu, Muwei Li, Junhui Zhang, Dayi Hu, Chuanyu Gao, On behalf of Henan STEMI registry study group
Background. Women hospitalized with ST-elevation myocardial infarction (STEMI) experience higher risk of early mortality than men. We aimed to investigate the potential impact of risk factors, clinical characteristics, and management among gender-related risk differences. Method. We analyzed 5063 STEMI patients prospectively enrolled from 66 hospitals during 2016–2018 and compared sex differences in
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The Relationship between Serum CXCL8 and ET-1 Expression Levels and Sepsis Complicated with Heart Failure Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-08-27 Jianlong Zhu, Changjun Song, Tingting Cai, Lulu Yi, Wei Zhang, Jing Zhong, Meirong Shen
Objective. The objective is to investigate the relationship between sepsis complicated with heart failure and the expression levels of CXC chemokine ligand 8 (CXCL8) and endothelin-1 (ET-1). Methods. A total of 128 sepsis patients accepted by the Ganzhou People’s Hospital from March 2019 to December 2021 were collected as observation objects, and they were separated into a simple sepsis group (86 cases)
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The Effect of TNF-α on CHD and the Relationship between TNF-α Antagonist and CHD in Rheumatoid Arthritis: A Systematic Review Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-08-24 Yezhou Qian, Menghui Mao, Feige Nian
Tumor necrosis factor-alpha (TNF-α) plays an important role in coronary heart disease (CHD), a chronic inflammatory process. Meanwhile, this pro-inflammatory factor is also involved in the pathogenesis of autoimmune diseases such as rheumatoid arthritis (RA). Patients with RA correspond to a higher risk of CHD. TNF-α antagonist, one of the main treatments for RA, may reduce the risk of CHD in patients
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Effect of PCSK9 Inhibitor on Contrast-Induced Acute Kidney Injury in Patients with Acute Myocardial Infarction Undergoing Intervention Therapy Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-08-23 Yu Ma, Lei Zha, Qi Zhang, Lu Cao, Ru Zhao, Jing Ma, Kai Hou, Yue Pan, Hongliang Cong, Ximing Li
Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors have been shown to inhibit pyroptosis and apoptosis, which play important roles in the development and progression of contrast-induced acute kidney injury (CI-AKI). However, to the best of our knowledge, no studies have investigated the potential effect of PCSK9 inhibitors on the prevalence of CI-AKI after percutaneous coronary intervention
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The Value of Serum YKL-40 and TNF-α in the Diagnosis of Acute ST-Segment Elevation Myocardial Infarction Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-08-23 Caoyang Fang, Zhenfei Chen, Jing Zhang, Jianyuan Pan, Xiaoqin Jin, Mengsi Yang, Luyao Huang
Background. Acute ST-segment elevation myocardial infarction (STEMI) is a serious cardiovascular disease that poses a great threat to the life and health of patients. Therefore, early diagnosis is important for STEMI patient treatment and prognosis. The purpose of this study was to investigate the value of serum YKL-40 and TNF-α in the diagnosis of STEMI. Methods. From October 2020 to February 2022
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Outcomes of Genetic Testing-Based Cardiac Rehabilitation Program in Patients with Acute Myocardial Infarction after Percutaneous Coronary Intervention Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-08-17 Xing Yu, Yuxuan Fan, Xiaopeng Sun, Xiaojing Wang, Qi Guo, Zhiqing Fan
Objective. There can be extreme variability between individual responses to exercise training, and the identification of genetic variants associated with individual variabilities in exercise-related traits could guide individualized exercise programs. We aimed to screen the exercise-related gene sensitivity of patients with acute myocardial infarction after PCI by establishing the gene spectrum of
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Synthesized 18-Lead Electrocardiogram in Diagnosing Posteriorstemi-Equivalentacute Coronary Syndrome in Patients with NSTEMI Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-08-17 Tomoki Horie, Rikuta Hamaya, Tomoyo Sugiyama, Hidenori Hirano, Masahiro Hoshino, Yoshihisa Kanaji, Tetsumin Lee, Taishi Yonetsu, Tetsuo Sasano, Tsunekazu Kakuta
Objective. To assess the clinical utility of synthesized V7–V9 ST-segment elevation (sV7-9 STE) in patients with 12-lead-electrocardiogram (ECG)-based non-STE myocardial infarction (NSTEMI) in diagnosing left circumflex artery (LCx) STEMI-equivalent acute coronary syndrome (ACS). Background. The 12-lead-ECG is insufficient for diagnosing patients with ACS, especially those with an LCx culprit. Methods
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Nontargeted Metabolomic Profiling of Huo-Tan-Chu-Shi Decoction in the Treatment of Coronary Heart Disease with Phlegm-damp Syndrome Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-08-12 Zhaoying Liang, Qiaohuang Zeng, Xiaomin Ou, Jing Cai, Taohua Lan, Weihui Lu
Background. Considered an effective supplementary therapy, traditional Chinese medicine (TCM) has been widely applied in the treatment of coronary heart disease (CHD). In this study, we aim to investigate the effects and mechanisms of Huo-Tan-Chu-Shi decoction (HTCSD, an in-hospital TCM prescription) in the treatment of CHD with the phlegm-damp syndrome in mice by non-targeted metabolomics with liquid
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Effectiveness and Safety of Four Aerobic Exercise Intensity Prescription Techniques in Rehabilitation Training for Patients with Coronary Heart Disease Cardiol. Res. Pract. (IF 2.1) Pub Date : 2022-07-15 Tao Chen, Huiying Zhu, Qingyuan Su
Background and Objectives. Exercise intensity is a key indicator for the safety and effectiveness of aerobic exercise program in cardiac rehabilitation (CR) in patients with coronary heart disease (CHD). The majority of CR guidelines recommend aerobic exercise prescription based on moderate intensity and suggest many techniques for setting the heart rate target of exercise to match the intensity. But