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A blunted nocturnal blood pressure decline is associated with all-cause and cardiovascular mortality. J. Hypertens. (IF 4.9) Pub Date : 2024-03-06 Alejandro de la Sierra, Natalie Staplin, Luis M Ruilope, Manuel Gorostidi, Ernest Vinyoles, Julián Segura, Colin Baigent, Bryan Williams
It has been suggested that a blunted nocturnal blood pressure (BP) decline is associated with a poor prognosis. Nevertheless, it remains unclear if an abnormal dipping is deleterious per se or it merely reflects an elevated BP during sleep. We aimed to assess the prognostic value of nocturnal BP decline, with or without concomitant elevated nocturnal BP.
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Retinal artery to vein ratio is associated with cerebral microbleeds in individuals with type 1 diabetes. J. Hypertens. (IF 4.9) Pub Date : 2024-02-28 Aleksi Tarkkonen, Ward Fickweiler, Marika Eriksson, Jennifer K Sun, Lena M Thorn, Paula Summanen, Per-Henrik Groop, Jukka Putaala, Juha Martola, Daniel Gordin
A third of asymptomatic individuals with type 1 diabetes (T1D) show signs of cerebrovascular disease in brain MRI. These signs associate with advanced stages of diabetic retinal disease, but not in mild or moderate retinopathy. We aimed to evaluate a wider spectrum of retinal changes by exploring the relationship between quantitative measures of retinal vessel parameters (RVP) and cerebrovascular changes
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Volume overload is a major characteristic in primary aldosteronism: a 3-year follow-up study. J. Hypertens. (IF 4.9) Pub Date : 2024-02-21 Eeva Kokko, Manoj Kumar Choudhary, Aapo Mutanen, Milja Honkonen, Antti Tikkakoski, Jenni K Koskela, Mari Hämäläinen, Eeva Moilanen, Marianna Viukari, Niina Matikainen, Pasi I Nevalainen, Ilkka Pörsti
We examined haemodynamics, focusing on volume balance and forward and backward wave amplitudes, before and after 2.8 years of targeted treatment of primary aldosteronism. Patients with essential hypertension and normotensive individuals were examined for comparison (n = 40 in each group).
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Predictors of blood pressure response to continuous positive airway pressure treatment in patients with sleep apnea. J. Hypertens. (IF 4.9) Pub Date : 2024-02-19 Maximilian Seidel, Muhammed F Kiziler, Marios Matiakis, Sebastian Bertram, Simon Wang, Felix S Seibert, Nina Babel, Timm H Westhoff
Sleep apnea is associated with hypertension. Metaanalyses indicate that treatment of sleep apnea by continuous positive airway pressure (CPAP) reduces blood pressure (BP) by a mean of 3 mmHg. To date, predictors of BP response to CPAP remain incompletely understood. We hypothesized that the magnitude of CPAP-induced BP reduction depends on baseline apnea-hypopnea index (AHI) and the extent of daytime
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Correlation between systolic blood pressure and mortality in heart failure patients with hypertension. J. Hypertens. (IF 4.9) Pub Date : 2024-02-16 Xueyan Lang, Cheng Peng, Yanxiu Zhang, Rong Gao, Bing Zhao, Yilan Li, Yao Zhang
The correlation between systolic blood pressure (SBP) and mortality in hypertensive patients with different phenotypes of heart failure (HF) has not been adequately studied, and optimal blood pressure control targets remain controversial. To explore the link between SBP and prognosis in all or three ejection fraction (EF) phenotypes of HF patients with hypertension.
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Short-duration dynamic power training with elastic bands combined with endurance training: a promising approach to hypertension management in older adults. J. Hypertens. (IF 4.9) Pub Date : 2024-02-12 Bruno Bavaresco Gambassi, Luiz Filipe Costa Chaves, Thiago Matheus da Silva Sousa, Maria Jacqueline Silva Ribeiro, Thiago Antonio Souza, Paulo Adriano Schwingel
Previous studies have investigated the effects of different combined training programs involving traditional resistance training and aerobic exercise on hemodynamic parameters and arterial stiffness in older adults. However, little is known about the impact of power training combined with endurance training on these variables in hypertensive older adults. Therefore, this study aimed to investigate
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Angiotensin-converting enzyme inhibitors, statins and the polypill in cardiovascular diseases prevention: ignorance is bliss or not? J. Hypertens. (IF 4.9) Pub Date : 2024-02-07 Francesco Natale, Paolo Golino, Giovanni Cimmino
The polypill strategy, which combines several medicines that simultaneously control different risk factors/diseases in a single pill, is one of the approaches used in cardiovascular therapy. In different guidelines, this one-pill combination therapy is suggested as first-line step in disease management. Because the cardiovascular diseases (CVD) pandemia, prevention is essential. The approaches that
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NOS3 prevents MMP-9, and MMP-13 induced extracellular matrix proteolytic degradation through specific microRNA-targeted expression of extracellular matrix metalloproteinase inducer in hypertension-related atherosclerosis. J. Hypertens. (IF 4.9) Pub Date : 2024-02-06 Rafael Ramírez-Carracedo, Ignacio Hernández, Rafael Moreno-Gómez-Toledano, Javier Díez-Mata, Laura Tesoro, Claudia González-Cucharero, Beatriz Jiménez-Guirado, Nunzio Alcharani, Laura Botana, Marta Saura, Jose L Zamorano, Carlos Zaragoza
Endothelial nitric oxide synthase (NOS3) elicits atheroprotection by preventing extracellular matrix (ECM) proteolytic degradation through inhibition of extracellular matrix metalloproteinase inducer (EMMPRIN) and collagenase MMP-13 by still unknown mechanisms.
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Age-dependent association of central blood pressure with cardiovascular outcomes: a cohort study involving 34 289 participants using the UK biobank. J. Hypertens. (IF 4.9) Pub Date : 2024-02-01 Shuqi Wang, Samuel Y S Wong, Benjamin H K Yip, Eric K P Lee
It remained unclear whether central blood pressures (BP) was more closely associated with cardiovascular disease (CVD) than brachial BP in different age groups.
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Sex differences in blood pressure phenotypes over time - the HELIUS study. J. Hypertens. (IF 4.9) Pub Date : 2024-01-31 Esther M C Vriend, Thomas A Bouwmeester, Oscar H Franco, Henrike Galenkamp, Aeilko H Zwinderman, Bert-Jan H van den Born, Didier Collard
Hypertension can be classified into different phenotypes according to systolic and diastolic blood pressure (BP). In younger adults, these phenotypical differences have different prognostic value for men and women. However, little is known about sex differences in the natural course of different BP phenotypes over time.
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Dietary approach for the treatment of arterial hypertension in patients with diabetes mellitus. J. Hypertens. (IF 4.9) Pub Date : 2024-01-30 Pedro Augusto M Barcellos, Angélica Dall'Agnol, Giovanna M Sandi, Luciana R Remonti, Sandra P Silveiro
The association of hypertension and diabetes mellitus is extremely common, increasing the mortality risk of patients, mainly by cardiovascular causes. Regarding the blood pressure (BP) targets to be achieved, most guidelines suggest levels of 130 mmHg for SBP and of 80 mmHg for DBP. Dietary modifications are quite effective, and many studies suggest that decreasing sodium intake and increasing potassium
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Concurrent exercise training potentiates the effects of angiotensin-converting enzyme inhibitor on regulatory systems of blood pressure control in ovariectomized hypertensive rats. J. Hypertens. (IF 4.9) Pub Date : 2024-01-25 Maycon Junior Ferreira, Danielle da Silva Dias, Gabriel do Carmo Silva, Amanda Aparecida de Araujo, Marina Rascio Henriques Dutra, Nathalia Bernardes, Maria-Cláudia Irigoyen, Kátia De Angelis
Enalapril has shown satisfactory potential in controlling increased and sustained blood pressure (BP). However, multiple dysregulated mechanisms that interact with each other and are involved in the pathophysiology of arterial hypertension may not be affected, contributing to the remaining cardiovascular risk. Using an exercise training protocol, we investigated whether adding both approaches to arterial
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Differences in the impact of newly diagnosed type 2 diabetes on cardiovascular mortality between normotensive and hypertensive individuals. J. Hypertens. (IF 4.9) Pub Date : 2024-01-24 Nobuo Sasaki, Ryo Maeda, Ryoji Ozono, Kenichi Yoshimura, Yukiko Nakano, Yukihito Higashi
We investigated the interrelationship between hyperglycemia and hypertension on cardiovascular mortality in the middle-aged and elderly people.
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Ability of a 24-h ambulatory cuffless blood pressure monitoring device to track blood pressure changes in clinical practice. J. Hypertens. (IF 4.9) Pub Date : 2024-01-24 Felicia C Derendinger, Annina S Vischer, Philipp Krisai, Thenral Socrates, Christina Schumacher, Michael Mayr, Thilo Burkard
There is an increasing number of cuffless blood pressure (BP) measurement (BPM) devices. Despite promising results when comparing single measurements, the ability of these devices to track changes in BP levels over 24 h related to an initial calibration BP (CalibBP) is unknown. Our aim was to analyse this ability in a cuffless device using pulse transit time.
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Greater use of antihypertensive medications explains lower blood pressures and better control in statin-treated than statin-eligible untreated adults. J. Hypertens. (IF 4.9) Pub Date : 2024-01-18 Brent M Egan, Jiexiang Li, Susan E Sutherland, Michael K Rakotz
Statins appear to have greater antihypertensive effects in observational studies than in randomized controlled trials. This study assessed whether more frequent treatment of hypertension contributed to better blood pressure (BP, mmHg) control in statin-treated than statin-eligible untreated adults in observational studies.
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Seasonal variation in ambulatory blood pressure control in patients on clinic blood pressure-guided antihypertensive treatment. J. Hypertens. (IF 4.9) Pub Date : 2024-01-18 Xiao-Fei Ye, Wen-Yuan-Yue Wang, Xin-Yu Wang, Qi-Fang Huang, Chang-Sheng Sheng, Yan Li, Ji-Guang Wang
We investigated seasonal variation in ambulatory blood pressure control in hypertensive patients on clinic blood pressure-guided antihypertensive treatment.
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Medication adherence and associated factors in newly diagnosed hypertensive patients in Japan: the life study. J. Hypertens. (IF 4.9) Pub Date : 2024-01-18 Kumi Sagara, Kenichi Goto, Megumi Maeda, Fumiko Murata, Haruhisa Fukuda
Hypertension is the leading cardiovascular risk factor worldwide. However, in Japan, only 30% of patients have their blood pressure controlled under 140/90 mmHg, and nonadherence to antihypertensives is thought to be a reason for the poor control of hypertension. We therefore sought to assess the adherence to hypertension treatment and to evaluate factors influencing patients' adherence in a large
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Dietary patterns associated with hypertension among stroke-free indigenous Africans: insights from the Stroke Investigative Research and Educational Network study. J. Hypertens. (IF 4.9) Pub Date : 2024-01-17 Akinkunmi Paul Okekunle, Osahon Jeffery Asowata, Onoja Matthew Akpa, Adekunle Gregory Fakunle, Ifeoluwa Bodunde, Morenikeji Komolafe, Oyedunni Arulogun, Fred Stephen Sarfo, Reginald Obiako, Godwin Osaigbovo, Godwin Ogbole, Abiodun Bello, Sunday Adeniyi, Benedict Calys-Tagoe, Lambert Appiah, Carolyn Jenkins, Olalekan Oyinloye, Hamisu Dambatta, Olayemi Balogun, Arti Singh, Abimbola Olalere, Yaw Mensah
The dietary factors associated with the high burden of hypertension among indigenous Africans remain poorly understood. We assessed the relationship between dietary patterns and hypertension among indigenous Africans.
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Blood pressure and variability responses to the down-titration of antihypertensive drugs. J. Hypertens. (IF 4.9) Pub Date : 2024-01-17 Byung Sik Kim, Yonggu Lee, Jeong-Hun Shin, Ran Heo, Hyun-Jin Kim, Jinho Shin
Several recent guidelines have proposed the gradual reduction of antihypertensive drugs for patients with well controlled blood pressure (BP). However, no studies have examined alterations in BP variability (BPV) during the down-titration of antihypertensives. This study aims to investigate changes in home BPV during the down-titration of antihypertensives.
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Inverse association between obesity and aortic pressure augmentation is attenuated in women: the Wakuya study. J. Hypertens. (IF 4.9) Pub Date : 2024-01-16 Kaname Tagawa, Yusuke Tsuru, Katsumi Yokoi, Takanori Aonuma, Junichiro Hashimoto
Pressure wave reflection predicts cardiovascular events in the general population. Obesity is negatively associated with pressure wave reflection. Muscular arterial diameter (responsible for pressure wave reflection) increases with obesity, and obesity-dependent dilation of muscular arteries is attenuated in women compared with men. We investigated the sex differences in the cross-sectional relationship
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Prediction of preeclampsia from retinal fundus images via deep learning in singleton pregnancies: a prospective cohort study. J. Hypertens. (IF 4.9) Pub Date : 2024-01-16 Tianfan Zhou, Shengyi Gu, Feixue Shao, Ping Li, Yuelin Wu, Jianhao Xiong, Bin Wang, Chenchen Zhou, Peng Gao, Xiaolin Hua
Early prediction of preeclampsia (PE) is of universal importance in controlling the disease process. Our study aimed to assess the feasibility of using retinal fundus images to predict PE via deep learning in singleton pregnancies.
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Comparison of cuff inflation and cuff deflation brachial sphygmomanometry with intra-arterial blood pressure as reference. J. Hypertens. (IF 4.9) Pub Date : 2024-01-16 Branko G Celler, Andy Yong, Imants Rubenis, Mark Butlin, Ahmadreza Argha, Rajan Rehan, Alberto Avolio
Conventional sphygmomanometry with cuff deflation is used to calibrate all noninvasive BP (NIBP) instruments and the International Standard makes no mention of calibrating methods specifically for NIBP instruments, which estimate systolic and diastolic pressure during cuff inflation rather than cuff deflation. There is however increasing interest in inflation-based NIBP (iNIBP) instruments on the basis
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Blood pressure lowering for kidney transplant recipients: systematic review with network meta-analysis. J. Hypertens. (IF 4.9) Pub Date : 2024-01-16 Patrizia Natale, Suetonia C Palmer, Allison Jaure, Valeria Saglimbene, Andrea Iannone, Amanda Sluiter, Jonathan Craig, Giovanni F M Strippoli
Hypertension affects 50-90% of kidney transplant recipients and is associated with cardiovascular disease and graft loss. We aimed to evaluate the comparative benefits and harms of blood pressure lowering agents in people with a functioning kidney transplant.
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Associations between lipid-lowering drugs and pregnancy and perinatal outcomes: a Mendelian randomization study. J. Hypertens. (IF 4.9) Pub Date : 2024-01-16 Runfang Wang, Jing Zhao, Li Li, Yan Huo
Mounting evidence has indicated that maternal dyslipidemia is associated with adverse obstetric outcomes, and the actions of lipid-lowering drugs in pregnant women remain controversial. Hence, this study aimed to appraise the causal relationship of lipid-lowering drugs [hydroxymethylglutaryl-coenzyme reductase (HMGCR) inhibitors, PCSK9 inhibitors, and NPC1L1 inhibitors] with pregnancy and perinatal
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High dietary salt intake attenuates nitric oxide mediated endothelium-dependent vasodilation and increases oxidative stress in pregnancy. J. Hypertens. (IF 4.9) Pub Date : 2024-01-15 Martina Vulin, Andrijana Muller, Ines Drenjančević, Petar Šušnjara, Zrinka Mihaljević, Ana Stupin
This study aimed to investigate the impact of dietary salt intake during normal pregnancy on maternal microvascular and macrovascular endothelium-dependent reactivity and oxidative stress level.
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Salt sensitivity risk derived from nocturnal dipping and 24-h heart rate predicts long-term blood pressure reduction following renal denervation. J. Hypertens. (IF 4.9) Pub Date : 2024-01-11 Gianni Sesa-Ashton, Revathy Carnagarin, Janis M Nolde, Ida Muente, Rebecca Lee, Vaughan G Macefield, Tye Dawood, Yusuke Sata, Elisabeth A Lambert, Gavin W Lambert, Antony Walton, Marcio G Kiuchi, Murray D Esler, Markus P Schlaich
Renal denervation (RDN) has been consistently shown in recent sham-controlled clinical trials to reduce blood pressure (BP). Salt sensitivity is a critical factor in hypertension pathogenesis, but cumbersome to assess by gold-standard methodology. Twenty-four-hour average heart rate (HR) and mean arterial pressure (MAP) dipping, taken by ambulatory blood pressure monitoring (ABPM), stratifies patients
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Association between anxiety and elevated blood pressure in adolescent patients: a single-center cross-sectional study. J. Hypertens. (IF 4.9) Pub Date : 2024-01-09 Yaritzy Astudillo, Sara Kibrom, Tanya Pereira, Sonia Solomon, Sankaran Krishnan, Dmitry Samsonov
Although anxiety is known to be associated with elevated blood pressure and hypertension in adults, this has not been studied in children. The aim of this study was to determine the association between anxiety and elevated blood pressures in adolescents.
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Accurate detection of Korotkoff sounds reveals large discrepancy between intra-arterial systolic pressure and simultaneous noninvasive measurement of blood pressure with brachial cuff sphygmomanometry. J. Hypertens. (IF 4.9) Pub Date : 2024-01-09 Branko G Celler, Andy Yong, Imants Rubenis, Mark Butlin, Ahmadreza Argha, Rajan Rehan, Alberto Avolio
Cardiovascular disease is the number 1 cause of death globally, with elevated blood pressure (BP) being the single largest risk factor. Hence, BP is an important physiological parameter used as an indicator of cardiovascular health. Noninvasive cuff-based automated monitoring is now the dominant method for BP measurement and irrespective of whether the oscillometric or the auscultatory method is used
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Effect of 12-week high-intensity interval training on hemodynamic variables at rest and during exercise in patients with obstructive sleep apnoea. J. Hypertens. (IF 4.9) Pub Date : 2024-01-04 Ozeas Lins-Filho, Antonio H Germano-Soares, José Lucas Porto Aguiar, José Ricardo Vieira de Almedia, Elton Carlos Felinto, Maria Julia Lyra, Danielle Batista Leite, Luciano Ferreira Drager, Breno Quintella Farah, Rodrigo Pinto Pedrosa
This study aimed to investigate the impact of 12 weeks of high-intensity interval training (HIIT) on hemodynamic variables at rest and during exercise in patients with obstructive sleep apnoea. Twenty-six obese adults with moderate-to-severe OSA (AHI = 42 ± 22.9 e/h) were randomly assigned to HIIT or a control group. Sleep parameters, ambulatorial, aortic, and during-exercise SBP and DBP were assessed
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Renalase mediates macrophage-to-fibroblast crosstalk to attenuate pressure overload-induced pathological myocardial fibrosis. J. Hypertens. (IF 4.9) Pub Date : 2024-01-04 Ru Fu, Nana You, Ruixuan Li, Xiexiong Zhao, Yihui Li, Xiaogang Li, Weihong Jiang
A potential antifibrotic mechanism in pathological myocardial remodeling is the recruitment of beneficial functional subpopulations of macrophages or the transformation of their phenotype. Macrophages are required to activate molecular cascades that regulate fibroblast behavior. Identifying mediators that activate the antifibrotic macrophage phenotype is tantamount to identifying the button that retards
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Standardized treatment protocols for hypertension: global availability, characteristics, and alignment with the hypertension guideline recommendations. J. Hypertens. (IF 4.9) Pub Date : 2023-12-18 Gautam Satheesh, Rupasvi Dhurjati, Mark D Huffman, Andres Rosende, Anthony Rodgers, Dorairaj Prabhakaran, Pedro Ordunez, Vivekanand Jha, Abdul Salam
Hypertension control is suboptimal globally. Implementing evidence-based, simple, standardized treatment protocols (STPs) has been instrumental in effectively and efficiently improving treatment and control of hypertension. We aimed to identify, characterize, and critically appraise hypertension STPs.
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Early vascular damage in retinal microcirculation in arterial hypertension: the Czech post-MONICA study. J. Hypertens. (IF 4.9) Pub Date : 2023-12-14 Renata Cífková, Joanna M Harazny, Jan Bruthans, Peter Wohlfahrt, Alena Hrubeš Krajčoviechová, Věra Lánská, Július Gelžinský, Markéta Mateřánková, Štěpán Mareš, Jan Filipovský, Otto Mayer, Roland E Schmieder
Retinal microcirculation reflects retinal perfusion abnormalities and retinal arterial structural changes at relatively early stages of various cardiovascular diseases. Wall-to-lumen ratio (WLR) may represent the earliest step in hypertension-mediated organ damage.Our objective was to compare functional and structural parameters of retinal microcirculation in a randomly selected urban population sample
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Blood pressure responses to testosterone therapy are amplified by hematocrit levels in opioid-induced androgen deficiency: a double-blind, randomized, placebo-controlled trial. J. Hypertens. (IF 4.9) Pub Date : 2023-12-14 Thomas Bastholm Olesen, Dorte Glintborg, Frederik Jøhnk, Michael Hecht Olsen, Marianne Skovsager Andersen
Our study aimed to examine the effect of testosterone replacement therapy (TRT) on blood pressure in opioid-treated men with relative hypogonadism, and whether the effect of TRT on blood pressure was modified by body composition, red blood cell levels, or carotid intima media thickness. Men (over 18 years old) receiving opioid treatment and total testosterone less than 12 nmol were randomly assigned
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Application of deep neural survival networks to the development of risk prediction models for diabetes mellitus, hypertension, and dyslipidemia. J. Hypertens. (IF 4.9) Pub Date : 2023-12-14 Yoshinori Sasagawa, Yosuke Inoue, Katsuya Futagami, Tomohiro Nakamura, Kiyohiro Maeda, Tomohiro Aoki, Naoko Fukubayashi, Mayumi Kimoto, Tetsuya Mizoue, Gakuse Hoshina
: Although numerous risk prediction models have been proposed, few such models have been developed using neural network-based survival analysis. We developed risk prediction models for three cardiovascular disease risk factors (diabetes mellitus, hypertension, and dyslipidemia) among a working-age population in Japan using DeepSurv, a deep feed-forward neural network.
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Rapid Gastric emptying in spontaneously hypertensive rats. J. Hypertens. (IF 4.9) Pub Date : 2023-12-14 Umber A Salman, Joyce G Schwartz, Alex C McMahan, Joel E Michalek, William T Phillips
To assess the rate of gastric emptying in spontaneously hypertensive rats (SHR) and to evaluate rapid gastric emptying as a possible predisposing factor for hypertension. Rapid gastric emptying of carbohydrates, known to elevate postprandial serum glucose, has been reported to occur in many insulin-resistant states, including hypertension. SHR exhibit insulin resistance similar to human hypertensive
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Combining renin-angiotensin system blockade and sodium-glucose cotransporter-2 inhibition in experimental diabetes results in synergistic beneficial effects. J. Hypertens. (IF 4.9) Pub Date : 2023-12-11 Edwyn O Cruz-López, Dien Ye, Daniel G Stolk, Marian C Clahsen-van Groningen, Richard van Veghel, Ingrid M Garrelds, Marko Poglitsch, Oliver Domenig, Rahi S Alipour Symakani, Daphne Merkus, Koen Verdonk, A H Jan Danser
Sodium-glucose cotransporter-2 (SGLT2) inhibition exerts cardioprotective and renoprotective effects, often on top of renin-angiotensin system (RAS) blockade. We investigated this in diabetic hypertensive (mREN2)27 rats.
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Factors influencing the continuation of home blood pressure measurement in community-dwelling older adults: the NOSE study. J. Hypertens. (IF 4.9) Pub Date : 2023-12-08 Arisa Wada, Mai Kabayama, Kayo Godai, Michiko Kido, Yuka Ohata, Naoko Murakami, Yuko Nakamura, Hiroko Yoshida, Sumiyo Hashimoto, Makiko Higashi, Hiromi Hatanaka, Takeshi Kikuchi, Keiji Terauchi, Sho Nagayoshi, Fumie Matsuno, Noboru Shinomiya, Kei Asayama, Takayoshi Ohkubo, Hiromi Rakugi, Yasuharu Tabara, Kei Kamide
This study aimed to identify the factors influencing home blood pressure measurement (HBPM) continuation in community-dwelling older adults.
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Reversal of arterial stiffness in medically and surgically treated unilateral primary aldosteronism. J. Hypertens. (IF 4.9) Pub Date : 2023-12-08 Zheng-Wei Chen, Che-Wei Liao, Chien-Ting Pan, Cheng-Hsuan Tsai, Yi-Yao Chang, Chin-Chen Chang, Bo-Ching Lee, Yu-Wei Chiu, Wei-Chieh Huang, Tai-Shuan Lai, Ching-Chu Lu, Jeff S Chueh, Vin-Cent Wu, Chi-Sheng Hung, Yen-Hung Lin
Hyperaldosteronism has adverse effects on cardiovascular structure and function. Laparoscopic adrenalectomy is the gold standard for patients with unilateral primary aldosteronism. For unilateral primary aldosteronism patients unable or unwilling to undergo surgery, the effects of mineralocorticoid receptor antagonists (MRAs) on the reversibility of arterial stiffness and other clinical data remain
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Simultaneous 24-h ambulatory blood pressure measurement on both arms: a consideration for improving hypertension management. J. Hypertens. (IF 4.9) Pub Date : 2023-12-07 Tomas L Bothe, Reinhold Kreutz, Martin Glos, Andreas Patzak, Niklas Pilz
Arterial hypertension is one of the common treatment goals in today's medicine. 24-h ambulatory blood pressure measurement (ABPM) performed by oscillometric cuff-based devices is considered as the gold standard in hypertension diagnostics. This study aims at examining the measurement accuracy of a widely used, ABPM device.
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The association of time-updated ambulatory blood pressure and renal progression in hypertensive patients with chronic kidney disease: post hoc analysis of ACCURATE study. J. Hypertens. (IF 4.9) Pub Date : 2023-12-07 Yunmi Kim, Jayoun Kim, Eunjeong Kang, Dha Woon Im, Taehee Kim, Hyuk Huh, Yeong Hoon Kim, Hyanglim Lee, Ji Hye Kim, Kook-Hwan Oh
: This study aimed to evaluate the effect of time-updated ambulatory blood pressure on chronic kidney disease (CKD) progression in patients with hypertension.
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Hypertension in the first blood pressure reading and the risk of cardiovascular disease mortality in the general population: findings from the prospective KORA study. J. Hypertens. (IF 4.9) Pub Date : 2023-12-07 Seryan Atasoy, Peter Henningsen, Hamimatunnisa Johar, Martin Middeke, Heribert Sattel, Birgit Linkohr, Ina-Maria Rückert-Eheberg, Margit Heier, Annette Peters, Karl-Heinz Ladwig
The risk of cardiovascular disease (CVD) mortality in individuals with an alerting reaction, assessed by hypertension in the first blood pressure (BP) reading but normal BP in further readings, remains unknown in the general population.
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Accumulation of advanced glycation end products in skin and increased vascular ageing in the general population: the Malmö Offspring Study. J. Hypertens. (IF 4.9) Pub Date : 2023-12-05 Amra Jujic, Gunnar Engström, Peter M Nilsson, Madeleine Johansson
Advanced glycation end product (AGE) is an established risk marker for diabetic vascular disease, and associated with the degree of diabetes complications, renal failure, and atherosclerosis in middle-aged and older individuals. The relationship between AGEs and aortic stiffness has not been thoroughly examined in the younger general population. We aimed to evaluate the association between AGEs and
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Should arm positioning matter in the diagnosis of orthostatic hypotension and hypertension? J. Hypertens. (IF 4.9) Pub Date : 2023-11-30 Annelise M G Paiva,Maria I C M Gomes,Érica A A Silva,Audes D M Feitosa,Marcus V B Malachias,Andrei C Sposito,Marco A Mota-Gomes,Wilson Nadruz
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Impact of hypertension treatment-time on cardiovascular outcomes: erroneous trial selection leading to suspect findings. J. Hypertens. (IF 4.9) Pub Date : 2023-11-30 José R Fernández,Artemio Mojón,Michael H Smolensky,Ramón C Hermida
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Nocturnal hypertension phenotypes and obstructive sleep apnoea. J. Hypertens. (IF 4.9) Pub Date : 2023-11-30 Grace Oscullo,Jose Daniel Gomez-Olivas,Miguel Ángel Martínez-García
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Consideration in the evaluation of follow-up of resistant hypertension. J. Hypertens. (IF 4.9) Pub Date : 2023-11-30 Decio Armanini,Chiara Sabbadin,Jacopo Manso,Marco Boscaro
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Authors' response to "Impact of hypertension treatment-time on cardiovascular outcomes: erroneous trial selection leading to suspect findings". J. Hypertens. (IF 4.9) Pub Date : 2023-11-30 Basel Abdelazeem,Othman Saleh,Abdelrahman Mahmoud,Mohamed Abuelazm
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Tobacco smoking is unhealthy for both female and male persons. J. Hypertens. (IF 4.9) Pub Date : 2023-11-30 Reinhold Kreutz,Veronique Cornelissen,Giuseppe Mancia
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Orthostatic hypotension an important phenotype in the 2023 European Society of Hypertension guidelines: how to measure it? J. Hypertens. (IF 4.9) Pub Date : 2023-11-30 Reinhold Kreutz,Paolo Palatini,George Stergiou,Giuseppe Mancia
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Gender differences in the association of serum uric acid with left ventricular hypertrophy should be focused. J. Hypertens. (IF 4.9) Pub Date : 2023-11-30 Takuya Kishi
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Attention to an important public health issue: deleterious vascular effects of acute exposure to passive smoking in adult young females. J. Hypertens. (IF 4.9) Pub Date : 2023-11-30 Mikail Yarlioglues,Abdurrahman Oguzhan
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Hypoxia-inducible factor-prolyl hydroxylase inhibitor Roxadustat (FG-4592) reduces renal fibrosis in Dahl salt-sensitive rats. J. Hypertens. (IF 4.9) Pub Date : 2023-11-28 Yoshiro Naito, Seiki Yasumura, Keisuke Okuno, Masanori Asakura, Takeshi Tsujino, Tohru Masuyama, Masaharu Ishihara
Although hypoxia-inducible factor-prolyl hydroxylase (HIF-PH) inhibitors have been developed for the treatment of renal anemia, their effects on cardiac and renal dysfunction remain unknown. We previously reported on Dahl salt-sensitive rats, in a rat model of salt-sensitive hypertension, that exhibited anemia and impaired expression of duodenal iron transporters after the development of hypertensive
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Dose-response association between physical activity and blood pressure among Chinese adults: a nationwide cross-sectional study. J. Hypertens. (IF 4.9) Pub Date : 2023-11-24 Tianjia Guan, Man Cao, Congyi Zheng, Haoqi Zhou, Xin Wang, Zuo Chen, Linfeng Zhang, Xue Cao, Yixin Tian, Jian Guo, Xueyan Han, Zengwu Wang
The aim of this study was to examine the dose-response associations of physical activity with blood pressure (BP) and hypertension risk among Chinese adults.
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FOXO3 longevity genotype attenuates the impact of hypertension on cerebral microinfarct risk. J. Hypertens. (IF 4.9) Pub Date : 2023-11-23 Kazuma Nakagawa, Randi Chen, G Webster Ross, Timothy A Donlon, Richard C Allsopp, D Craig Willcox, Brian J Morris, Bradley J Willcox, Kamal H Masaki
The G-allele of FOXO3 SNP rs2802292, which is associated with human resilience and longevity, has been shown to attenuate the impact of hypertension on the risk of intracerebral hemorrhage (ICH). We sought to determine whether the FOXO3 G-allele similarly attenuates the impact of hypertension on the risk of cerebral microinfarcts (CMI).
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Long-term blood pressure variability and frailty risk in older adults. J. Hypertens. (IF 4.9) Pub Date : 2023-11-21 Michelle A Fravel, Michael E Ernst, Robyn L Woods, Lawrence Beilin, Zhen Zhou, Suzanne G Orchard, Enayet Chowdhury, Christopher M Reid, Arm Saifuddin Ekram, Sara E Espinoza, Mark R Nelson, Nigel Stocks, Kevan R Polkinghorne, Rory Wolfe, Joanne Ryan
In healthy older adults, the relationship between long-term, visit-to-visit variability in blood pressure (BP) and frailty is uncertain.
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Lactobacillus induced by irbesartan on spontaneously hypertensive rat contribute to its antihypertensive effect. J. Hypertens. (IF 4.9) Pub Date : 2023-11-17 Yanling Xiong, Yanping He, Zhi Chen, Tianyuan Wu, Yalan Xiong, Yilei Peng, Xuechun Yang, Yujie Liu, Jian Zhou, Honghao Zhou, Wei Zhang, Yan Shu, Xiong Li, Qing Li
Hypertension is linked to gut dysbiosis. Here, the impact of the angiotensin receptor antagonist irbesartan on the gut microbiota of spontaneously hypertensive rats (SHR) were investigated. In addition, we assessed their contribution to its antihypertensive effect.
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A cost-analysis of managing secondary and apparent treatment-resistant hypertension in a specialist multidisciplinary hypertension clinic. J. Hypertens. (IF 4.9) Pub Date : 2023-11-16 Louise Rabbitt, James Curneen, Anna Hobbins, Darragh Browne, Mary Joyce, David Lappin, John William McEvoy, Paddy Gillespie, Michael Conall Dennedy
A knowledge gap exists around the costs and budget impact of specialist hypertension clinics. This study reports on the cost of providing care in a multidisciplinary hypertension clinic staffed by nephrologist, endocrinologist and cardiologist, which manages patients with suspected secondary hypertension and/or apparent treatment-resistant hypertension. The aim of this study is to provide the evidence
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Association of work-related psychosocial factors and day-to-day home blood pressure variation: the Finn-Home study. J. Hypertens. (IF 4.9) Pub Date : 2023-11-16 Saana Karelius, Jaana Pentti, Eeva Juhanoja, Antti Jula, Seppo Koskinen, Teemu J Niiranen, Sari Stenholm
Stress, and particularly job strain, has been found to associate with ambulatory blood pressure (BP). Moreover, BP is known to vary between days. One potential over-looked factor underlying this day-to-day BP variation could be work-related psychosocial factors. Thus, we aimed to study the association between job strain, job demands, job control and day-to-day BP variation.
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Use trends of chlorthalidone and hydrochlorothiazide among United States adults with hypertension: National Health and Nutrition Examination Survey 2009-2018. J. Hypertens. (IF 4.9) Pub Date : 2023-11-16 Genevieve Hale, Emily Puchades, Gema Jacomino, Layall El-Mcharfie, Alexandra Perez
To estimate the national prevalence of chlorthalidone and hydrochlorothiazide use among adults diagnosed with hypertension by sociodemographic subgroup, healthcare access status, and clinical factors.
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Cardiovascular outcomes according to on-treatment systolic blood pressure in older hypertensive patients: a multicenter cohort using a common data model. J. Hypertens. (IF 4.9) Pub Date : 2023-11-15 Ju Hyeon Kim, Hyung Joon Joo, Se Hwa Chung, Yunjin Yum, Yong Hyun Kim, Eung Ju Kim
In the growing population of older patients with hypertension, limited evidence supports an association between lowering systolic blood pressure (SBP) and decreased adverse events. We aimed to investigate cardiovascular outcomes according to on-treatment SBP in older hypertensive patients.