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Vitamin D and the microbiota connection: understanding its potential to improve COPD outcomes Egypt. J. Bronchol. Pub Date : 2024-03-15 Asmaa Ali, Liang Wu, Sameh Samir Ali
The mucosa of the respiratory system is an essential site for local vitamin D synthesis, degradation, and signaling. It modulates the inflammatory and immune response by saving the integrity of the mucosal barrier and killing the invading pathogen through the induction of antimicrobial peptides. The proper functioning of the immune system within the respiratory system is influenced by the complex interactions
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A case series of co-infection in Mycobacterium tuberculosis and other pathogens: insights from nanopore sequencing Egypt. J. Bronchol. Pub Date : 2024-03-11 Wei Shu, Wenlong Chen, Lin Yao, Ming Sun, Min Gao, Zanyan Wan, Wei Xie, Yanjuan Lei, Tao Wang
Tuberculosis (TB) continues to be a major global health burden, and co-infection with other pathogens further complicates the diagnosis and treatment of this infectious disease. The present retrospective study aimed to evaluate the clinical utility of nanopore sequencing in identifying co-infection caused by Mycobacterium tuberculosis (M.tb) and other pathogens. Patients with M.tb co-infection from
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Predictive accuracy of years score in diagnosis of pulmonary embolism Egypt. J. Bronchol. Pub Date : 2024-03-05 Hussien Fayiad, Heba Moussa, Yara Nosair, Amira Ismail Mostafa
Pulmonary embolism (PE) is a sudden obstruction of pulmonary arteries usually associated with a high rate of mortality due to acute right ventricular failure. Early diagnosis is of much importance because most patients die within the first hours of presentation. Emergency management is usually highly valuable and right heart failure is potentially reversible. Multidetector computed tomography pulmonary
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Correction: Hematological parameters as predictors of OSA severity Egypt. J. Bronchol. Pub Date : 2024-02-29 Rasha Mohamed Hendy, Basma M. Hani, Salwa H. Mohammed
Correction: Egypt J Bronchol 18, 3 (2024) https://doi.org/10.1186/s43168-023-00252-z The original publication of this article contained an incorrect author name. The incorrect and correct information is shown in this correction article [1]. The original article has been updated. Incorrect Basma M. Hani Correct Basma H. Hani Hendy RM et al (2024) Hematological parameters as predictors of OSA severity
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12-month risk factor evaluation for persistent pulmonary symptoms in long COVID-19 patients Egypt. J. Bronchol. Pub Date : 2024-02-29 Eman M. Emad Eldin, Randa S. Mohammed, Mahmoud M. E. L. Batanony, Laila A. Al-Sharawy
Knowledge of the sequelae of new coronavirus disease 2019 (COVID-19) is still limited owing to the relative recent onset of the disease. However, the study of other different types of coronavirus infections prior to COVID-19 infection reports that the patients may experience persistent symptoms following the infection. Assessment and follow-up of persistent respiratory symptoms in patients recovered
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Role of STREM-1 for early prediction of ventilator-associated pneumonia in pediatrics Egypt. J. Bronchol. Pub Date : 2024-02-22 Tarek Ahmed Abdelgawad, Maha Ahmad Anwar, Sondos Mohamed Magdy, Mohamed El-Sayed Abd El-Maksoud Abd El-Maksoud
TREM-1 (setting off receptor imparted on myeloid cells-1) is an immunoreceptor. Neutrophils, monocytes/macrophages, and endothelial cells all express TREM-1. This work aimed to evaluate the role of STREM-1 in ventilator-associated pneumonia (VAP) early prediction in pediatrics. This case–control research involved 56 children aged from 1 month to 5 years old, who were admitted to the pediatric intensive
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Study of serum Ykl-40 level and its relationship to BODE index in patients with chronic obstructive pulmonary disease Egypt. J. Bronchol. Pub Date : 2024-02-20 Aya Elsayed Farrag, Anwar Ahmed Elganady, Enas Elsaid Mohammed, Abeer Shawky ElHadidi, Heba Ahmed Eshmawey
Chronic obstructive pulmonary disease (COPD) is a significant global health concern characterized by growing rates of mortality and morbidity. The purpose of this work was to evaluate the serum YKL-40 level and its relationship to body mass index (BMI), obstruction of airflow, dyspnea, exercise capacity (BODE) index, and the extent of COPD. This prospective work was carried out on 70 adult male patients
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Subclinical pleuro-pulmonary disease in patients with SLE: functional and radiological methods Egypt. J. Bronchol. Pub Date : 2024-02-19 Hanaa S. Hamed, Mohammed M. N. Abozaid, Enas Mekawy
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with highest prevalence of chest involvement; however, early detection of subclinical pleuropulmonary diseases may improve the quality of life and prognosis of patients. This study aimed to identify the subclinical pleuro-pulmonary involvement in SLE patients without respiratory symptoms. A total of 228 patients diagnosed with SLE
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Endobronchial chondrosarcoma presenting as recurrent pneumonia: a rare pulmonary tumour Egypt. J. Bronchol. Pub Date : 2024-02-12 Rahul Kumar Gupta, Amita Mason, Shirazi Nadia, Manoj Kumar
Chondrosarcoma is a group of bone tumours made up of cells responsible for cartilage production. It usually affects the axial skeleton, including the pelvis, scapula and base of the skull with frequent metastasis to the lungs. Primary pulmonary involvement with chondrosarcoma is rarely seen. In this case report, we will discuss a case of endobronchial chondrosarcoma presenting as recurrent pneumonia
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Study of the prevalence and predictive factors of sleep-disordered breathing in patients with interstitial lung diseases Egypt. J. Bronchol. Pub Date : 2024-02-06 Nabila Ibrahim Laz, Mohammad Farouk Mohammad, Mona Mahmoud Srour, Waleed Ramadan Arafat
Interstitial lung diseases (ILDs) are parenchymal lung conditions that are chronic, progressive, and have a high morbidity and mortality rate. Due to restrictions in their gas exchange and ventilatory dysfunction, ILD patients are probably at risk for sleep-disordered breathing (SDB). Sixty-nine patients with diffuse parenchymal lung diseases identified by high-resolution computed tomography (HRCT)
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Response to prone positioning in COVID-19 patients with acute respiratory distress syndrome: a retrospective observational study Egypt. J. Bronchol. Pub Date : 2024-02-01 Zeinab Adawy, Ayman Iskandarani, Abeer Alharbi, Yara A. Iskandarani, Gufran Salem, Dalya A. Iskandarani, Abdul Rahman H. Ali, Mohammed A. Salem, Eman Sobh
COVID-19 pneumonia and respiratory failure are the leading causes of death in COVID-19 patients. Prone positioning was hypothesized to improve oxygenation in ARDS patients and is being studied in COVID-19, but the current evidence is still unclear regarding survival and hospitalization. We aimed to investigate the effect of prone positioning on oxygenation in patients with COVID-19 pneumonia and ARDS
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Evaluation of brain white matter changes on MRI in patients newly diagnosed with obstructive sleep apnea compared with the control group Egypt. J. Bronchol. Pub Date : 2024-02-01 Farzaneh Khoroushi, Yasmin Davoodi, Amirhossein Fathabadi, Reihane Bakhshi, Yasamin Sharifian, Maryam Salehi, Leila Ghofranyha, Ehsan Hassannejad, Farnaz Kharaghani
Obstructive sleep apnea (OSA) is nowadays introduced as a risk factor for white matter brain changes. Research on OSA and white matter changes provides contradictory evidence for the contextual link between the two conditions. This study aimed to determine the prevalence and severity of OSA and changes in the brain's white matter and the relationship between severity levels of both diseases. This was
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Assessment of interleukin 6 (IL-6) as a marker of inflammation among adult patients with pulmonary tuberculosis in Zaria, Nigeria Egypt. J. Bronchol. Pub Date : 2024-01-31 Mairiga Sa’ad, Abdullah A. Abba, Bolanle Olufunke Priscilla Musa, Abdurrahman El-fulaty Ahmad, Musa Mohammed
Tuberculosis (TB) remains a significant cause of morbidity and mortality worldwide. Complications of the disease are associated with the host’s inflammatory response. The study aimed to determine the plasma level of interleukin-6 as a biomarker of inflammation among adult patients with pulmonary tuberculosis in Zaria. Method This was a cross-sectional study. Blood samples were taken from 30 treatment-naïve
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Correlation of obstructive sleep apnea severity and lipid profile level Egypt. J. Bronchol. Pub Date : 2024-01-29 Rasha Mohamed Hendy, Mona Ahmed Elawady, Hend Elsayed Nasr, Rizk Sayed R. Sarhan
Obstructive sleep apnea (OSA) is accompanied by different metabolic disorders and is linked with a heightened incidence of cardiovascular diseases and death. The information actively engaged in relating obstructive sleep apnea and dyslipidemia is quite uncertain. This research intended to determine the correlation between obstructive sleep apnea severeness and lipid profile abnormalities. Our study
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Clinical features and predictors of metabolic syndrome among obstructive sleep apnea patients Egypt. J. Bronchol. Pub Date : 2024-01-25 Safy Zahid Kaddah, Merna Hamada Korany, Eman Kamal Ibrahim
Obstructive sleep apnea (OSA) and metabolic syndrome (MetS) are two diseases associated with an increased risk of cardio-metabolic complications and both share the same risk factors such as obesity and smoking. To study the clinical features and predictors of MetS in OSA patients. A cross-sectional study was conducted in the sleep lab of the Pulmonology Department at Kasr Al-Ainy Hospital, Cairo University
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Role of point of care ultrasound in management of deteriorating respiratory intensive care unit patients and its impact on outcome Egypt. J. Bronchol. Pub Date : 2024-01-22 Maha Mohammed Elgabry, Eman Shebl, Mohamed Saad El-Shetry, Enaam I. Elsayed, Niveen ELSayed Zayed
Point of care ultrasonography (POCUS) is a real time examination that can be used in the emergency room and intensive care unit (ICU). It can provide low-cost modality in short period of time that can help the clinician in better management the ICU patients. The aim of the current work was to evaluate the impact of POCUS (focused heart, lung, IVC and Doppler lower limb) in improving the outcome of
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Relationship between airway inflammation, small airway dysfunction, and frequency of acute exacerbations in patients with chronic obstructive pulmonary disease Egypt. J. Bronchol. Pub Date : 2024-01-15 Taha Taha Abdelgawad, Azza Eliwa, Ahmed Fouda, Doaa Khedr, Ramy A. Abdelsalam, Ahmed Elsayed Mansour
Recurrent exacerbations in COPD patients are associated with accelerated reduction in lung function. Airway inflammation and small airway dysfunction were recognized for a long time as an essential feature of COPD. To study the relationship between neutrophilic airway inflammation, small airway dysfunction, and frequency of acute exacerbations in COPD patients. This was a cross-sectional study. Thirty
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Hematological parameters as predictors of OSA severity Egypt. J. Bronchol. Pub Date : 2024-01-10 Rasha Mohamed Hendy, Basma H. Hani, Salwa H. Mohammed
Obstructive sleep apnea syndrome (OSAS) is a common disease that has a prevalence of 6 to 13% of the adult population. It is characterized by recurrent obstruction partial or total upper airway and subsequent paroxysmal nocturnal hypoxia, leading to intermittent arousals from sleep and excessive daytime sleepiness. This work aimed to evaluate the relationship between the hematological parameters in
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Predictors of mortality in critically ill children hospitalized with laboratory- confirmed COVID-19 pneumonia Egypt. J. Bronchol. Pub Date : 2024-01-02 Rehab Elmeazawy, Ahmed Mohammed Farid EL-Moazen
Children with COVID-19 infection had fewer severe symptoms, which made it challenging to publish clinical data for this age group. This study aimed to determine the clinical features, laboratory markers, and predictors of mortality in children hospitalized in Pediatric Critical Care Units with COVID-19 pneumonia. This retrospective research included all children between the age of ≥ 1 month and 18
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Systemic inflammatory response index as an independent predictor of severity in patients with obstructive sleep apnea Egypt. J. Bronchol. Pub Date : 2024-01-02 Seham Ezzat Fathy Elfeky, Asmaa Ali, Eman M. Moazen, Mohammad Hamad Alhassoon, Nesma A. Elzanaty, Nouf Mubarak Alazmi, Liang Wu, Mai M. Saleh
Chronic inflammation plays a crucial role in developing various cardiovascular and metabolic disorders. Obstructive sleep apnea (OSA) is a unique condition characterized by the coexistence of cardiovascular and metabolic disturbances, where chronic inflammation may exacerbate disease progression and severity. This study investigated how different hematological inflammatory cells and mediators can serve
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Bedside test for estimating stiff index in mechanically ventilated ARDS patient: a pilot study Egypt. J. Bronchol. Pub Date : 2023-12-18 E. Fatma, Gamal A. Rahman, M. Algendy, M. Mahmoud, A. Mona, T. Yousra
Stiff index is defined as the proportion of lung tissue elasticity in relation to chest wall elasticity to pertain to its cyclic tidal volume. It is meant to reflect the risk of overloading lung pressure. Introducing the Stiff index into bedside management determines the pressure needed to keep the lung open with no risk of barotrauma. Aim of the work The primary endpoint was to highlight the stiff
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Impact of obstructive sleep apnea on cognition, mood, and fatigue: an MRI-based study Egypt. J. Bronchol. Pub Date : 2023-12-13 Rania Ahmad Sweed, Rana Alsaeed Rizk Abd Elghany, Anwar Ahmed Elganady, Enas Elsayed Mohamed, Jaidaa Farouk Mekky, Mohamed Mahmoud Elshafei
Obstructive sleep apnea disrupts the normal sleep cycle and is associated with many adverse consequences such as cardiovascular disease, DM, psychological problems, depression, decreased cognitive function, reduced quality of life, structural brain changes, and fatigue. This work aimed to study the MRI structural brain changes and to assess the neurocognitive function, depression, and fatigue using
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Successful removal of an iatrogenic pleural foreign body—pigtail catheter, using a semi-rigid thoracoscope Egypt. J. Bronchol. Pub Date : 2023-12-01 Pradeep Bajad, Sourabh Pahuja, Arjun Khanna, Satyam Agarwal
Tube thoracostomy stands as the conventional treatment for pleural diseases. Nevertheless, pigtail catheters have gained traction due to their smaller size, potentially resulting in reduced complications. Despite the enhanced safety and ease of insertion associated with pigtail catheters, it is crucial to recognize that procedural complications can arise irrespective of the drainage method employed
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No gender-specific differences in comorbidities in patients with chronic obstructive pulmonary disease due to alpha-1 antitrypsin deficiency Egypt. J. Bronchol. Pub Date : 2023-11-29 Josef Yayan, Kurt Rasche
A deficiency in alpha-1 antitrypsin (A1AD) leads to increased activity of proteolytic enzymes. The consequence is a damage of airways and alveoli and, ultimately, the development of emphysema and chronic obstructive pulmonary disease (COPD). Gender-specific differences in terms of comorbidities are still unclear due to the rarity of this genetic autosomal recessive disease. This retrospective observational
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Incidence of thrombophilic gene polymorphism (MTHFR C677T) in Egyptian COVID-19 patients and its clinical implications Egypt. J. Bronchol. Pub Date : 2023-11-23 Eman Badawy Abdelfattah, Sahar Samir Abdelmaksoud, Heba Mohamed Shalaby, Saad Shehata Abo-zid, Mahmoud M. Aboulmagd M. Youssef, Ahmed Ali Elshebiny, Hieba Gamal Ezzelregal
COVID-19 has an important component of organ damage which is COVID-19-associated coagulopathy. It is necessary to assess the risk in patients to develop a thrombophylaxis plan. The higher prevalence of key thrombophilic genetic variants, such as mutation of the C677T-methylenetetrahydrofolate reductase (MTHFR) gene in Eastern Mediterranean countries, makes it challenging to use the same criteria in
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Quercetin for inhibition of inflammatory responses and oxidative stress in lung injury model: a systematic review and meta-analysis Egypt. J. Bronchol. Pub Date : 2023-11-22 Ghufran Lutfi Ismaeel, Mohanad Ali Abdulhadi, Lubna R. Al-Ameer, Sally Salih Jumaa, Israa M. Essa, Abduladheem Turki Jalil, Abbas F. Almulla, Ronak Taher Ali
Acute lung injury (ALI) is a life-threatening clinical syndrome with high morbidity and mortality. The main pathological features of ALI are increased alveolar-capillary membrane permeability, edema, uncontrolled migration of neutrophils to the lungs, and diffuse alveolar damage, resulting in acute hypoxemic respiratory failure. We performed a systematic review and meta-analysis to elucidate the antioxidant
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Predictors of obstructive sleep apnea in patients with chronic obstructive pulmonary disease Egypt. J. Bronchol. Pub Date : 2023-11-22 Safy Zahid Kaddah, Yousef Mohamed Amin Soliman, Heba Mousa, Naglaa Moustafa, Eman Kamal Ibrahim
The co-existence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) is known as overlap syndrome, and both conditions share common risk factors and are associated with co-morbidities and poor outcomes. Sixty stable COPD patients were included in the study. We assessed body measurements, pulmonary functions to diagnose and assess COPD severity, arterial blood gases, STOB-BANG
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COVID-19 Post- vaccination infection among hospital attendants in Qena city Egypt. J. Bronchol. Pub Date : 2023-11-16 Reham Abdallah Mohamed, Ahmed Mohammed Mahmoud Hany, Asmaa Abdelhakim Nafady
The duration of immunological persistence in COVID-19-vaccinated individuals is considered a matter of concern. Some studies have shown that anti-SARS-CoV-2 antibodies degrade rapidly. Due to diminishing immunity after vaccination, some people may catch an infection again after receiving the COVID-19 vaccine. The purpose of the present study was to measure the COVID-19 post-vaccination infection reported
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Pulmonary mucormycosis presenting as a tumor-like mass in an uncontrolled diabetic patient: a rare case report Egypt. J. Bronchol. Pub Date : 2023-11-16 Alireza Ziaei Moghaddam, Reza Basiri, Nema Mohamadian Roshan
Mucormycosis is a life-threatening infection caused by fungi in the Mucorales species. It mainly affects diabetes patients and other immune-compromised hosts. The infection can involve multiple organ systems, with the lungs being the second most common site. We report a case of a 40-year-old female who had a mass that resembled a tumor, a very rare manifestation of the disease which we were able to
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Extra pulmonary versus pulmonary presentation of COVID-19 patients: comparative study Egypt. J. Bronchol. Pub Date : 2023-11-15 Hend M. Esmaeel, Hamdy S. Mohamed, Asmaa R. Khalaf, Hamza A. Mahmoud, Doaa Gadallah
The respiratory system is the most frequently affected system by COVID-19. However, a variety of extra-pulmonary systems can be influenced by COVID-19 with subsequent morbidity and mortality. This study aim is to report the most frequent extra pulmonary presentations of COVID-19 with comparison to patients with primary pulmonary presentation. Risk factors for ICU admission in both groups were examined
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Assessment of atypical pneumonia by chest ultrasonography Egypt. J. Bronchol. Pub Date : 2023-11-08 Ahmed Sameh Sayed, Mona Mansour Ahmed, Khaled Mohamed Wagih, Haytham Samy Diab, Ahmed Mohamed Hussein
Patients with pneumonia exhibit similar clinical presentations despite having different causative organisms; thus, a rapid and easy test is needed to differentiate between the diseases. Here, we use lung ultrasound to discriminate between causative organisms in correlation with other diagnostic modalities. This descriptive cross-sectional study was carried out on 67 patients diagnosed with atypical
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Safety and efficacy of high flow nasal canula in patients with mild hypercapnia Egypt. J. Bronchol. Pub Date : 2023-11-08 Mohammed A. Ibrahim, Magdy Emara, Mohammed Shehta
High flow nasal canula is usually used for management of acute hypoxemic failure; however, it may have a potential therapeutic benefits in hypercapnia as it can alter tidal volume, end expiratory volume, positive end expiratory pressure, and respiratory rate. Evaluate safety and efficacy of application HFNC (high flow nasal canula) for patients with mild hypercapnia. A prospective interventional study
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Impact of comorbid pulmonary disease on COVID-19 disease severity and outcome: a retrospective cohort study Egypt. J. Bronchol. Pub Date : 2023-11-07 Sally Magdy, Reem Elkorashy, Eman Hany Elsebaie, Hebatallah Hany Assal, Hoda M. Abdel-Hamid
Identifying patients with comorbid pulmonary disease may guide prognosis and aid in developing strategies regarding who would benefit the most from vaccines. This study was designed to clarify the influence of comorbid lung disease on COVID-19 severity and outcome. This is a retrospective cohort analysis of 587 COVID-19 patients. The clinical, laboratory, and imaging data and comorbidities as reported
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Imaging changes of oil aspiration over time in children: a case series Egypt. J. Bronchol. Pub Date : 2023-11-07 Masoud Mahdavi Rashed, Mojtaba Haji Hosseini, Behnam Beizae, Seyed Ali Alamdaran, Anahita Alizadeh, Seyed Javad Seyedi, Ehsan Hassannejad, Nahid Tavakolizadeh
Oil aspiration pneumonia is an uncommon form of lung disease due to aspiration or inhalation of oil-containing products. The present study reports the changes process of radiological findings over time in four children. For 2 years, four cases (17 months until 3.5 years) with aspiration oil-containing (petroleum or benzene) products were referred to a tertiary center, Akbar Children’s Hospital, Mashhad
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Assessing the early returns of robotic-assisted bronchoscopy in a patient population at high risk for cancer: factors associated with a diagnostic procedure and pathologic outcomes Egypt. J. Bronchol. Pub Date : 2023-11-06 Rami Naaman, Christopher M. Kapp, Odile David, Kevin Kovitz, Benjamin Aronson, Kevin Haas
Lung cancer remains the most common cause of cancer-related deaths in the USA. Successful implementation of lung cancer screening programs has led to increased detection of peripheral pulmonary lesions (PPL). Robotic-assisted bronchoscopy (RB) is a relatively novel tool used to safely diagnose PPN. Additionally, with the developing precision of personalized medicine and targeted therapy, obtaining
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Diagnostic yield of combined ultrasound-guided fine needle aspiration and core needle biopsy versus either technique alone in peripheral lung and pleural lesions Egypt. J. Bronchol. Pub Date : 2023-11-06 Rania Ahmed Sweed, Yehia Mohamed Khalil, Hany Amin Sharawy, Eman Sheta Ali Gawdat Alsawy, Mina Botros
Ultrasound (US) has become an integral tool for chest assessment as it provides crucial information on pleural pathologies and peripherally located lung lesions. To assess the diagnostic yield of combined fine needle aspiration (FNAB) and core needle biopsy (CNB) versus each technique ultrasound-guided in peripheral lung and pleural lesions. The present study enrolled 30 patients presenting to Alexandria
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The yield of rigid thoracoscopy in patients of undiagnosed exudative pleural effusion and comparison of pleural fluid and thoracoscopic findings between tuberculosis and malignancy Egypt. J. Bronchol. Pub Date : 2023-11-03 Hemant Kumar, Mohammad Arif, Sachin Kumar, Ved Prakash, Ajay Kumar Verma, Chanchal Rana, Saumya Shukla, R. A. S. Kushwaha
Medical thoracoscopy is an essential tool in the evaluation of patients with pleural effusion who remain undiagnosed despite a thorough pleural fluid workup. Malignancy and tuberculosis are the two most common etiologies in such patients having completely different prognoses. Therefore, correct diagnosis is very important before starting treatment. This study was planned to study the yield of rigid
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Clinical, physiological, and radiological different phenotypes of COPD patients Egypt. J. Bronchol. Pub Date : 2023-10-23 Islam Galal, Zeinab Rabie, Shazly Ahmed, Ahmed Hamdy Mhsb, Samah Kotb
COPD is a heterogeneous lung disorder with multiple phenotypes and endotypes. This study aimed to identify the diverse clinical, physiological, and radiological phenotypes of COPD. Moreover, to provide whether there was a possible relation between FEV1%, FVC%, and FEV1/FVC ratio, [both before and after broncho-dilation with the diameters of the airway at three diverse levels throughout both inspiratory
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The diagnostic role of C2PAC index in cases of sepsis-induced coagulopathy (SIC) Egypt. J. Bronchol. Pub Date : 2023-10-18 Mohamed Shaaban Mousa, Salwa Hassan Ahmed, Fatma Abdel Wahab Abdel Maksoud, Soliman Belal Soliman, Ahmed A. Tantawy
To study the potential role of the C2PAC index (a ratio of soluble type C lectin-like receptor 2 level sCLEC-2 and platelet count) in sepsis-induced coagulopathy with the possibility of using this index as an early predictor in sepsis and sepsis-induced coagulopathy. Our case–control study included a total of 86 participants divided into 2 groups: group I is the case group consisting of 56 patients
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Acute phase reactants in non-COVID-19 community-acquired pneumonia Egypt. J. Bronchol. Pub Date : 2023-10-18 Yosri Akl, Ahmed Elkomy, Eman Kamal Ibrahim
Acute phase reactants (APR) are markers of inflammation that could be applied for the assessment of community-acquired pneumonia (CAP) severity in association with various pneumonia severity scores. So, the aim of the study was to assess levels of APR such as total leucocytic count (TLC), platelets, neutrophils, neutrophils-to-lymphocyte ratio (NLR), CRP, D-dimer, ferritin, and ESR in patients with
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Role of long-term oxygen therapy in interstitial lung diseases Egypt. J. Bronchol. Pub Date : 2023-10-16 Sahar Farghly Yossif, Atef F. El-Qarn, Asmaa M. M. El-Tayeb, Mohamed F. Abd El-Ghany
Long-term oxygen therapy in patients with interstitial lung diseases is frequently given in order to enhance gas exchange, lessen dyspnea, and increase physical activity. To evaluate how individuals with hypoxemia and interstitial lung disease respond to long-term oxygen therapy. Between October 2019 and July 2021, this prospective analytical (cross-sectional) study was carried out at the Assiut University
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Obstructive sleep apnea in patients with type 2 diabetes mellitus in Egyptian population Egypt. J. Bronchol. Pub Date : 2023-10-05 Rania Ahmad Sweed, Nashwa Hassan Abd El Wahab, Mona Saeed El Hooshy, Eman Youssef Morsy, Dina Mohsen Shetta
Sleep disordered breathing (SDB) is a widespread disorder with a wide range of harmful outcomes including obstructive sleep apnea (OSA), central sleep apnea (CSA), or sleep-related hypoventilation. The aim of the present study was to screen for the occurrence of sleep apnea syndrome in patients with type 2 diabetes mellitus (DM) and to evaluate the relation between the presence of sleep apnea and the
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Sonographic assessment of mean pulmonary artery pressure and diaphragmatic excursion in chronic respiratory failure patient after using home non-invasive positive pressure ventilation Egypt. J. Bronchol. Pub Date : 2023-10-04 Maha E. Alsadik, Waheed M Shouman, Doaa Mostafa Gad, Mohamed Elsaid Elfeqy
Non-invasive positive pressure ventilation (NIPPV) has emerged as a recognized and effective long-term therapeutic approach for individuals suffering from chronic respiratory insufficiency resulting from various diverse disorders. Nevertheless, providing home non-invasive positive pressure ventilation encounters several challenges, including compliance, training inadequacies, and limited resources
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Correlation between rectus femoris muscle cross-sectional area and the severity of airflow limitation in COPD patients Egypt. J. Bronchol. Pub Date : 2023-10-02 Rania Ahmed Sweed, Yehya Mohamed Khalil, Anwar Ahmed Elganady, Mahmoud Abdelrahman Abdelgawad Ali
Peripheral muscle dysfunction is a well-recognized complication of COPD associated with exercise (in)tolerance and worse prognosis. The evaluation of peripheral muscle integrity is an attractive marker in COPD patients. The aim of the study was to identify the correlation between the rectus femoris muscle cross-sectional area (RFCSA) and the severity of airway obstruction in COPD patients using ultrasound
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NIV support bronchoscopy by tracheostomy after decannulation failure: avoid new tracheostomy—case report and review analysis Egypt. J. Bronchol. Pub Date : 2023-09-19 Hadeel Mohamed, Mostafa Elshazly, Antonio Esquinas
Decannulation is an essential step in liberating tracheostomised patients from mechanical ventilation. There is a paucity of literature on tracheostomy decannulation methods and procedures, leaving the decision to expert opinion and institutional guidelines. Failure to decannulate may result from several reasons, such as severe dysphagia, retention of copious secretions requiring invasive airway clearing
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Early application of continuous positive airway pressure in COVID-19 patients at risk of obstructive sleep apnea Egypt. J. Bronchol. Pub Date : 2023-09-19 Zeinab Emad, Mohammed A. Ibrahim, TahaTaha Abdelgawad, Abdelbaset M. Saleh
Respiratory support is an essential part in treating COVID-19 patients at risk for developing respiratory failure, and this become certain if associated with other comorbidities specifically obstructive sleep apnea (OSA). To evaluate the role of early use of continuous positive airway pressure (CPAP) in management of moderate to severe COVID-19 patients at risk of OSA. This was experimental clinical
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Computed tomography pulmonary angiogram in a poly-trauma patient undergoing veno venous extracorporeal membrane oxygenation: our experience in diagnosing pulmonary embolism Egypt. J. Bronchol. Pub Date : 2023-09-15 Ali Al Bshabshe, Senthil Purushothaman, Nasser Mohammed Alwadai, Hussam Haider Omer, Om Prakash Palanivel
Extracorporeal membrane oxygenation (ECMO) is an adapted form of the heart–lung machine that provides cardiopulmonary bypass life support for critically ill patients with acute cardiac and/or respiratory failure who are unresponsive to standard medical and surgical therapies. Although ECMO therapy has advanced significantly, complications like thrombosis and bleeding continue to be substantial, necessitating
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Correlation between serum uric acid and pulmonary arterial hypertension based on echo probability in patients with obstructive sleep apnea syndrome Egypt. J. Bronchol. Pub Date : 2023-09-11 Rania Ahmad Sweed, Ghadeer Mostafa Mohamed Bedair, Ahmed Yousef Shaban, Hany Amin Shaarwy
Obstructive sleep apnea–hypopnea syndrome is the most common form of SRBDs. Recurrent hypoxia, which accompanies OSAHS, increases the degradation of ATP, which in turn increase uric acid concentration that can be used as a biomarker of tissue hypoxia in OSAHS. There is still debate about whether OSAHS is an independent contributor to pulmonary arterial hypertension. This study aimed to correlate serum
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Electrolyte profile in COVID-19 patients: insights into outcomes Egypt. J. Bronchol. Pub Date : 2023-09-11 Mohamed Sorour Mohamed, Essamedin M. Negm, Mahmoud Hosny Zahran, Mahmoud M. Magdy, Ahmed Abdulsaboor Mohammed, Dalia Anas Ibrahim, Ahmed E. Tawfik, Tarek Hamdy Hassan
Some evidence has provided that electrolyte disorders may be present upon presentation of patients with COVID-19 infection. We investigated serum sodium, potassium, calcium, magnesium, and phosphorus levels in large numbers of critically ill COVID-19 patients to identify its possible prognostic value in these patients. This retrospective study included patients confirmed with COVID-19 infection admitted
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Quality of life and its relation to pediatric asthma severity Egypt. J. Bronchol. Pub Date : 2023-09-04 Heba A. Ali
Bronchial asthma is a global health problem that negatively affects the quality of life (QOL) of both children and their caregivers. However, there is a paucity of data regarding the impact of QOL on asthma severity in the pediatric population. Therefore, we aimed to examine the effect of health-related QOL of children with asthma and their caregivers on the level of asthma control and the degree of
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Safety and efficacy of tocilizumab in critically ill patients with COVID-19: an observational study Egypt. J. Bronchol. Pub Date : 2023-09-01 Ghada A. Youssef, Khalid M. Wagih, Hossam M. Abdel Hamid
Since the coronavirus disease 2019 (COVID-19) outbreak has rapidly propagated with a high mortality rate, it is currently considered a global emergency. Worldwide, the number of patients with severe acute respiratory syndrome caused by coronavirus 2 is steadily rising. Pneumonia, severe symptoms of acute respiratory distress syndrome (ARDS), and multiple organ failure can all occur in COVID-19 patients
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Correlation between the serum level of ferritin and D-dimer and the severity of COVID-19 infection Egypt. J. Bronchol. Pub Date : 2023-08-30 Eman Badawy AbdelFattah, Ashraf Mokhtar Madkour, Shimaa Mohamed I. Amer, Noha Othman Ahmed
Many laboratory biomarkers were used for diagnosis of COVID-19 infection; however, their accuracy to assess the severity and prognosis are still to be evaluated. This study aims to correlate between the serum ferritin and D-dimer levels and the severity of COVID-19 infection and its outcome. Retrospective data retrieval of 150 confirmed COVID-19 infection patients admitted in Ain Shams University Specialized
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d-dimer as a biomarker for COVID-19-associated pulmonary thromboembolism: a narrative review from molecular pathways to the imaging findings Egypt. J. Bronchol. Pub Date : 2023-08-28 Shadi Beidollahkhani, Farzad Fayedeh, Ahmad Shoja, Ehsan Hassan Nejad, Mahdieh Hoseinpour, Faezeh Fazlpour, Asma Payandeh, Masoud Pezeshki Rad, AmirAli Moodi Ghalibaf
The coronavirus disease 2019, also known as COVID-19, imposed various challenges to healthcare and became a pandemic accompanied by a high rate of mortality. This infection has many manifestations and affects nearly all body systems. The circulatory and coagulation systems also seem to be affected. Studies show elevated rates of thrombotic events within COVID-19 patients such as disseminated intravascular
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Diffuse alveolar hemorrhage (DAH): a rare presentation of metastatic angiosarcoma Egypt. J. Bronchol. Pub Date : 2023-08-11 Amrith B P, Mansi Sharma, Ullas Batra
Angiosarcoma is an uncommon and highly aggressive malignant tumor. Angiosarcoma presenting as diffuse alveolar hemorrhage (DAH) is rare. A young female who presented with history of dyspnea was found to have features of DAH on radiological evaluation. Angiosarcoma was confirmed from the histopathological examination of the underlying lung nodule. Management with the palliative chemotherapy showed clinical
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Microbiological analysis of nosocomial pneumonia at Tanta University Chest Hospital Egypt. J. Bronchol. Pub Date : 2023-08-11 Amira Abdelgalil Elkholy, Mohamed Sayed Hantera, Ayman Hassan Abd El-Zaher, Mai M. Mwafy, Amira Samy Tourky, Mostafa Tarek Abo Elnoor, Mohamed Torky
Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) represent a major health problem among hospitalized patients leading to consequent morbidity and mortality specially after Covid-19 era and spread of multidrug-resistance organisms)MDRO) in hospitals. This study aimed to analyze the commonest microorganisms responsible for HAP and VAP at Tanta University Chest Hospital. This
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Reversibility of acute pulmonary hypertension after resolution of exacerbation in patients with COPD Egypt. J. Bronchol. Pub Date : 2023-08-11 Muhammad E. Atta, Yehia M. Khalil, Tamer S. Morsi, Amany F. Elbehairy
To the Editor, The presence of pulmonary hypertension (PH)in patients with chronic obstructive pulmonary disease (COPD) is associated with an increased risk of acute exacerbation (AE-COPD) [1]. Furthermore, when admitted for AE-COPD, patients with associated PH are at increased risk of lengthy hospital stays and decreased survival [2]. It has been previously reported that pulmonary artery pressure
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Role of MRI in diagnosis of pulmonary embolism Egypt. J. Bronchol. Pub Date : 2023-08-09 Abolhasan Haseib Mohammad, Hossam Mohammed Mostafa, Hasan Ibarhim Megaly, Mohamed Zidan Mohamed, Mohamad Gaber Taha, Sherif M. Abdelal
Pulmonary embolism (PE) is considered a serious condition and has clinical challenges in diagnosis. Computed tomography pulmonary angiography (CTPA) is considered the gold standard in PE diagnosis. Contrast-enhanced MRA also has a strong useful role in the diagnosis. Our study aims to assess the role of non-contrast MRA in diagnosis of acute pulmonary embolism compared to either CT pulmonary angiography
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Pulmonary mycoses among pulmonary tuberculosis in Kebbi State North Western Nigeria Egypt. J. Bronchol. Pub Date : 2023-08-09 Mohammed Bashar Danlami, Adesina Muibi Adefowepo, Sahabi Sule Manga, Tajudeen Olanrewaju Yahaya, Mari Bata Mshelia, Zaharaddin Muhammad Kalgo
Pathogenic fungi are the source of the fungal illness known as pulmonary mycosis. The prevalence of pulmonary mycoses among patients with pulmonary tuberculosis is continuously rising, despite improvements in the disease’s diagnosis, treatment, and management. Three hundred clinically confirmed patients with pulmonary tuberculosis were recruited for this study. Sputum samples were collected and analyzed
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Cognitive impact on patients with COVID-19 infection Egypt. J. Bronchol. Pub Date : 2023-07-26 Ahmad Mohammad Abdo Kheder Shaddad, Aliaë Abd Rabou Mohamed Hussein, Amal Mohamed Aly Tohamy, Waleed Gamal Elddin Khaleel
SARS‐COV‐2 infection reframed medical knowledge in many aspects, yet there is still a lot to be discovered. Coronavirus disease 19 (COVID-19) can cause neuropsychiatric, psychological, and psychosocial impairments. Literature regarding the cognitive impact of COVID-19 is still limited. This study aims to evaluate cognitive function, anxiety, and depression among patients with coronavirus disease 19
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Prevalence and impact of comorbidities in hospitalized patients with COVID-19: a study from Saudi Arabia Egypt. J. Bronchol. Pub Date : 2023-07-25 Saad M. A. alqahtani, Naif S. Al Saglan, Ali A. AlShehry, Ali Hawan, Badraltamam A. A.Dafalla, Nahid A. S. Mohamed, Ali S. Kadasah, Muhammad A.Qureshi, Nourah A. Al-Shahrani, Abdulaziz S. Y. Alfaifi, Mohammed A. Alqahtani, Fawwaz A. Alshafa, Ali A. Alsalem, Yahya A. Al-Imamah, Alahmari Abdullah, Saad A. S. Alzulfah, Ibrahim M. A. Mahmoud, Usama E. Abuelhassan
In this study, we aimed to address the prevalence of comorbidities and their impact on the outcomes of hospitalized COVID-19 patients admitted to a large tertiary Saudi Arabian hospital. This is a retrospective study that included all adults with COVID‑19 admitted to a large tertiary Saudi Arabian hospital, between January 1, 2021, and September 30, 2022. The study outcomes were the prevalence of comorbidities