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Recent Insights into the Environmental Determinants of Childhood Asthma Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-03-18
Abstract Purpose of Review Ubiquitous environmental exposures, including ambient air pollutants, are linked to the development and severity of childhood asthma. Advances in our understanding of these links have increasingly led to clinical interventions to reduce asthma morbidity. Recent Findings We review recent work untangling the complex relationship between air pollutants, including particulate
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Environmental Interventions for Preventing Atopic Diseases Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-03-16 Scott Pfirrman, Ashley Devonshire, Andrew Winslow
Purpose of Review In this review, we detail the exposome (consisting of environmental factors such as diet, microbial colonization, allergens, pollutants, and stressors), mechanistic and clinical research supporting its influence on atopic disease, and potentiation from climate change. We highlight contemporary environmental interventions and available evidence substantiating their roles in atopic
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Type 2 and Non-type 2 Inflammation in the Upper Airways: Cellular and Molecular Alterations in Olfactory Neuroepithelium Cell Populations Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-03-16 Concepció Marin, Isam Alobid, Mauricio López-Chacón, Camilo R. VanStrahlen, Joaquim Mullol
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Multidisciplinary Decision-Making—ITAlian Consensus After Two Years of Real Practice on the Management of Severe Uncontrolled CRSwNP by Biologics (ITACA Study) Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-03-12 Eugenio De Corso, Carlotta Pipolo, Marco Caminati, Elena Cantone, Veronica Seccia, Lorenzo Cecchi, Eustachio Nettis, Massimiliano Garzaro, Giancarlo Ottaviano, Matteo Gelardi, Carlo Cavaliere, Enrico Heffler, Fabio Pagella, Ernesto Pasquini, Matteo Trimarchi, Stefania Gallo, Ignazio La Mantia, Sara Torretta, Davide Mattavelli, Cristiano Caruso, Andrea Matucci, Alessandra Vultaggio, Gianluca Bellocchi
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Alpha-Tryptase as a Risk-Modifying Factor for Mast Cell–Mediated Reactions Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-03-09 Hannah Shin, Jonathan J. Lyons
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A Review of Shared Decision-Making, Published Protocols, and Post-desensitization Strategies in Oral Immunotherapy (OIT) Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-03-05 Susan Laubach, Edwin H. Kim, Matthew Greenhawt, Sally Bailey, Aikaterini Anagnostou
Purpose of Review The aim of this review is to highlight key published oral immunotherapy (OIT) protocols and post-desensitization strategies for the major food allergens and to cover important concepts to consider when evaluating OIT for food-allergic patients. Shared decision-making should help identify patient and family values which will help influence the type of evidence-based protocol and maintenance
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Food Insecurity and Health Inequities in Food Allergy Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-02-29 Akilah A. Jefferson, Lauren Davidson, Amy M. Scurlock, Jessica Stern
Purpose of Review The intersection of food insecurity among those with food allergy is a growing public health concern. Both food allergy and food insecurity have profound implications on health, social, and economic outcomes. The interaction of social determinants of health, poverty, racism, housing insecurity, and access to care has direct impact on individuals with food allergy. Recent Findings
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The Natural History and Risk Factors for the Development of Food Allergies in Children and Adults Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-02-28
Abstract Purpose of Review This narrative review explores food allergy prevalence and natural history stratified by life stages, especially in context of evolving knowledge over the last few decades. Recent Findings The prevalence of food allergy remains highest in early childhood with common food triggers being cow’s milk, soy, hen’s egg, wheat, peanut, tree nuts, sesame, fish, and shellfish. This
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The Future of Food Allergy Management: Advancements in Therapies Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-02-23 Idil D. Ezhuthachan, Michele Beaudoin, Anna Nowak-Wegrzyn, Brian P. Vickery
Purpose of Review To review current and future treatment options for IgE-mediated food allergy. Recent Findings Recent years have seen major developments in both allergen-specific and allergen-non-specific treatment options, with the first FDA-approved peanut oral immunotherapy (OIT) product becoming available in 2020. In addition to OIT, other immunotherapy modalities, biologics, adjunct therapies
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Reversible Elevation of Tryptase Over the Individual's Baseline: Why is It the Best Biomarker for Severe Systemic Mast Cell Activation and MCAS? Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-02-03 Peter Valent, Cem Akin, Michel Arock
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Cognitive Impairment and Depression in Mastocytosis: A Synthesis of the Literature Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-01-31
Abstract Purpose of Review Symptoms of depression and cognitive dysfunction are commonly reported in mastocytosis. The aims of this review paper are to summarize the current literature on cognitive dysfunction and depressive symptoms, elucidate some of the mechanistic pathways underlying depressive symptoms in mastocytosis, identify gaps in the literature, and offer guidance for future research in
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Predictors of Clonality and Underlying Mastocytosis in Mast Cell Activation Syndromes Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-01-25 David Gonzalez-de-Olano, Iván Álvarez-Twose
Purpose of Review Mast cell (MC) activation can present with a wide range of symptoms. The mechanisms that cause such activation are varied. One of them is the presence of clonal MCs which is defined, within other possible changes, by the presence of a somatic, activating mutation in the KIT gene. The clinical course and prognosis of patients with this underlying disease may be different from other
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Precautionary Allergen Labeling: Avoidance for All? Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-01-25 Allison Schaible, Jamie Kabourek, Wendy Elverson, Carina Venter, Amanda Cox, Marion Groetch
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Psychosocial Impact of Food Allergy on Children and Adults and Practical Interventions Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-01-23 Theresa A. Bingemann, Jennifer LeBovidge, Lisa Bartnikas, Jennifer L. P. Protudjer, Linda J. Herbert
Purpose of Review IgE- and non-IgE-mediated food allergies are increasing in prevalence in children and adults worldwide. A food allergy diagnosis can be associated with a sense of overwhelm and stress and commonly has a negative impact on quality of life. Recent Findings While there is an increased recognition of the psychosocial effects of food allergy, the current research reflects the experience
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Using the Right Criteria for MCAS Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-01-20
Abstract Purpose of Review The current article aims to provide a comprehensive update on diagnostic criteria for mast cell activation syndrome (MCAS), addressing challenges in diagnosing and classifying MCAS and its variants. Recent Findings In recent years, there has been a significant increase in our knowledge regarding the underlying mechanisms responsible for the activation of mast cells (MCs)
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Urine Mast Cell Mediators in the Evaluation and Diagnosis of Mast Cell Activation Syndrome Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-01-18 Dayne Voelker, Thanai Pongdee
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Mast Cells in Aspirin-Exacerbated Respiratory Disease Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-01-13
Abstract Purpose of Review Aspirin-exacerbated respiratory disease (AERD) is a syndrome of high type 2 inflammation and is known to critically involve mast cell activation. The mast cell is an important cell in the baseline inflammatory processes in the upper and lower airway by maintaining and amplifying type 2 inflammation. But it also is prominent in the hypersensitivity reaction to COX-1 inhibition
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Mast Cell–Targeting Therapies in Mast Cell Activation Syndromes Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-01-13 Vito Sabato, Michiel Beyens, Alessandro Toscano, Athina Van Gasse, Didier G. Ebo
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Epidemiology and the Growing Epidemic of Food Allergy in Children and Adults Across the Globe Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2024-01-12
Abstract Purpose of Review Food allergies are immune-mediated, complex disorders, which are the source of increasing health concern worldwide. The goal of this review is to present an updated summary of the food allergy (FA) burden among children and adults across different populations, focusing on research from the past 5 years. Recent Findings FAs impact a growing number of global residents—particularly
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A Review of Pollen Counting Networks: From the Nineteenth Century into the Twenty-first Century Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-12-28 Richard W. Lucas, Landon Bunderson
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Remission in Type 2 Inflammatory Diseases: Current Evidence, Unmet Needs, and Suggestions for Defining Remission in Chronic Rhinosinusitis with Nasal Polyps Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-12-12 Marco Caminati, Eugenio De Corso, Giancarlo Ottaviano, Carlotta Pipolo, Michele Schiappoli, Veronica Seccia, Francesca Romana Spinelli, Edoardo Vincenzo Savarino, Paolo Gisondi, Gianenrico Senna
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Biomarkers of Autoimmune Chronic Spontaneous Urticaria Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-12-08 Désirée Larenas-Linnemann
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Effects of Endoscopic Sinus Surgery on Olfactory Function Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-12-01 L. Stefano Ramirez-Gil, J. J. Ley-Tomas, J. C. Hernaiz-Leonardo, Isam Alobid, Joaquim Mullol, J. C. Ceballos-Cantu
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The Impact of Ambient and Wildfire Air Pollution on Rhinosinusitis and Olfactory Dysfunction Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-12-04 Sophie E. Yu, Tejas S. Athni, Margaret B. Mitchell, Xiaodan Zhou, Simon Chiang, Stella E. Lee
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Expert Consensus on SABA Use for Asthma Clinical Decision-Making: A Delphi Approach Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-11-22 Njira Lugogo, Maeve O’Connor, Maureen George, Rajan Merchant, Greg Bensch, Jay Portnoy, John Oppenheimer, Mario Castro
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Endoscopic Extended Sinus Surgery for Patients with Severe Chronic Rhinosinusitis with Nasal Polyps, the Choice of Mucoplasty: A Systematic Review Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-11-22 Daniel Martin-Jimenez, Ramon Moreno-Luna, Alfonso Cuvillo, Jaime Gonzalez-Garcia, Juan Maza-Solano, Serafin Sanchez-Gomez
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Treatments of Epistaxis in Hereditary Hemorrhagic Telangiectasia: Systematic Review and Network Meta-Analysis Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-11-23 Wirach Chitsuthipakorn, Minh P. Hoang, Dichapong Kanjanawasee, Kachorn Seresirikachorn, Kornkiat Snidvongs
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Type 2 Biomarkers for the Indication and Response to Biologics in CRSwNP Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-11-21 Cui-Lian Guo, Fei-Fan Liu, De-Yun Wang, Zheng Liu
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An Emerging Role of Extracellular Traps in Chronic Rhinosinusitis Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-11-07 Siyuan Zhang, Zhenlin Wang
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Neuromyelitis Optica: Pathogenesis Overlap with Other Autoimmune Diseases Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-10-27 Nadim Taheri, Julie Sarrand, Muhammad S. Soyfoo
Purpose of Review Neuromyelitis optica (NMO) is an auto-immune disease essentially depicted by optic neuritis and transverse myelitis. Per se, NMO was initially believed to be a sub-type of multiple sclerosis with typical demyelinating cerebral lesions and optic nerve inflammation. More recently, corroborating lignes of evidence have strengthened the concept of the spectrum of diseases associated with
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Overview and Current Advances in Dapsone Hypersensitivity Syndrome Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-10-07 Zhen-Zhen Wang, Rui Zeng, Zi-Wei Wu, Chen Wang, Hai-Qin Jiang, Hong-Sheng Wang
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Allergen Stability in Food Allergy: A Clinician’s Perspective Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-09-04 Larissa Koidl, Salvatore Alessio Gentile, Eva Untersmayr
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Effects of Allergen Exposure and Environmental Risk Factors in Schools on Childhood Asthma Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-08-31 Eva Yarsky, Tina M. Banzon, Wanda Phipatanakul
Purpose of Review This review aims to assess the prevalence of common allergen exposures and environmental risk factors for asthma in schools, examine the underlying mechanisms of these environmental risk factors, and explore possible prevention strategies. Recent Findings Cockroach, mouse, dust mites, fungi, viral infections, ozone pollution, and cleaning products are common allergen exposures and
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Omalizumab Treatment in Uncontrolled Asthma and CRSwNP Patients, with Previous Endoscopic Sinus Surgery, to Improve Quality of Life and Endoscopic Outcomes: a Two-Year Real-Life Study Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-08-30 Juan Maza-Solano, Amparo Callejon-Leblic, Daniel Martin-Jimenez, Ramon Moreno-Luna, Jaime Gonzalez-Garcia, Alfonso Cuvillo, Serafin Sanchez-Gomez
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The Role of IgA in the Manifestation and Prevention of Allergic Immune Responses Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-08-23 Stephan Scheurer, Ann-Christine Junker, Chaoqi He, Stefan Schülke, Masako Toda
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Management of Mechanical Nasal Obstruction Isolated or Associated to Upper Airway Inflammatory Diseases in Real Life: Use of both Subjective and Objective Criteria Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-08-10 Carla Merma-Linares, M. Dolores Martinez, Miriam Gonzalez, Isam Alobid, Enric Figuerola, Joaquim Mullol
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Occupational Rhinitis: An Update Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-07-15 Jose Zamora-Sifuentes, Jill A. Poole
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Air Pollution and Diet: Potential Interacting Exposures in Asthma Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-07-13 Emily Brigham, Alisa Hashimoto, Neil E. Alexis
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Autoimmune Inflammatory Eye Disease: Demystifying Clinical Presentations for the Internist Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-07-12 Richmond Woodward, Sri Meghana Konda, Dilraj S. Grewal
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The Use and Teaching of Telemedicine in Allergy/Immunology Training Programs Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-07-07 Emily Robbins, Kirti Johal, Anjeni Keswani
Purpose of Review The use of telemedicine has greatly increased since the onset of the coronavirus disease 2019 (COVID-19) pandemic. This review discusses the types of telemedicine, current telehealth curricula in medical education, and benefits and disadvantages of incorporation of telemedicine into Allergy/Immunology training programs. Recent Findings The majority of Allergists/Immunologists use
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Establishing a Virtual Home Assessment Program: from Concept to Implementation as a Result of the COVID-19 Pandemic Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-07-05 Ryan Allenbrand, Anita DiDonna, Jenny Marshall, Kevin Kennedy
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Multiple Sclerosis Pathogenesis and Updates in Targeted Therapeutic Approaches Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-07-04 Eleni S. Vasileiou, Kathryn C. Fitzgerald
Purpose of Review In this review, we provide a comprehensive update on current scientific advances and emerging therapeutic approaches in the field of multiple sclerosis. Recent Findings Multiple sclerosis (MS) is a common disorder characterized by inflammation and degeneration within the central nervous system (CNS). MS is the leading cause of non-traumatic disability in the young adult population
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Podcasting in Clinical Allergy and Immunology: Our Experience and a Review of the Current Landscape Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-07-04 Payel Gupta, Wajiha Kazmi, Gregory Della Penna, Kortney Kwong Hing
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Pathophysiological Link Between Chronic Rhinosinusitis and Ear Disease Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-07-03 Christian Calvo-Henriquez, Eugenio Di Corso, Isam Alobid, Elena Cantone, Tiziana Di Cesare, Joaquim Mullol
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Computer-Assisted Clinical Diagnosis and Treatment Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-06-23 Nadia Hamid, Jay M. Portnoy, Aarti Pandya
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Role of Small Molecule Ligands in IgE-Mediated Allergy Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-06-23 Kriti Khatri, Andrea O’Malley, Christina Linn, Krzysztof Kowal, Maksymilian Chruszcz
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The Impact of Climate Change on Asthma and Allergic-Immunologic Disease Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-06-07 Grace Kelly, Osatohamwen I. Idubor, Sophie Binney, Paul J. Schramm, Maria C. Mirabelli, Joy Hsu
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The Relationship of Parasite Allergens to Allergic Diseases Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-06-03 Luis Caraballo, Kevin Llinás-Caballero
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Neurosarcoidosis: Diagnostic Challenges and Mimics A Review Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-05-31 Jeffrey Shen, Elijah Lackey, Suma Shah
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Allergies Come Clean: The Role of Detergents in Epithelial Barrier Dysfunction Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-05-26 Benjamin L. Wright, Mia Y. Masuda, Danna R. Ortiz, Adelyn Dao, Blake Civello, Grace C. Pyon, Aliviya R. Schulze, James A. Yiannas, Matthew A. Rank, Hirohito Kita, Alfred D. Doyle
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The Impact of Air Pollution on Atopic Dermatitis Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-05-26 Austin Lai, Kelly Owens, Surya Patel, Matilda Nicholas
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Online Education in Allergy and Immunology: An Update to Conferences Online in Allergy (COLA) Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-05-25 Melissa Anderson, Christopher Miller
Purpose of Review Online resources have become an essential component of medical education. We describe here our long standing but unique approach to providing online education in the specialty of allergy and immunology and its impact. Recent Findings In this article, we report the process and updates to our online conferencing curriculum known as Conferences Online in Allergy (COLA). The program
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Environmental Exposure to Foods as a Risk Factor for Food Allergy Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-05-25 Andrew V. Turner, Johanna M. Smeekens
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Lessons from Dairy Farmers for Occupational Allergy and Respiratory Disease Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-05-16 J. Seidel, S. Magzamen, Y. H. Wang, V. Neujahr, J. W. Schaeffer
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Effects of Tezepelumab on Quality of Life of Patients with Moderate-to-Severe, Uncontrolled Asthma: Systematic Review and Meta-Analysis Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-05-16 Gabriel Cavalcante Lima Chagas, Débora Xavier, Lorena Gomes, Juliana Ferri-Guerra, Rafael Enrique Hernandez Oquet
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Use of the Electronic Health Record for Monitoring Adverse Drug Reactions Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-05-16 Anum F. Muzaffar, Sandra Abdul-Massih, James M. Stevenson, Santiago Alvarez-Arango
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The Role of Defensins as Pollen and Food Allergens Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-05-13 Valentina Cosi, Gabriele Gadermaier
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The Effects of Wildfire Smoke on Asthma and Allergy Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-05-12 Terry L. Noah, Cameron P. Worden, Meghan E. Rebuli, Ilona Jaspers
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Multisystemic Inflammatory Syndrome in Children and Kawasaki Disease: Parallels in Pathogenesis and Treatment Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-05-12 Laura Cannon, M. Jay Campbell, Eveline Y. Wu
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Revisiting the Definition of Anaphylaxis Curr. Allergy Asthma. Rep. (IF 5.5) Pub Date : 2023-05-12 Catherine Hammond
Purpose of Review Anaphylaxis is a common phenomenon that has been studied for many decades. Despite this, there is still disagreement among organizations regarding the precise definition for anaphylaxis. This article discusses the difference between the proposed definitions of anaphylaxis. Furthermore, the most up-to-date literature on specific subtypes of anaphylaxis is reviewed, and implications