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Hypercapnia and its relationship with respiratory infections Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2024-03-15 Elena Campaña-Duel, Adrian Ceccato, Luis Morales-Quinteros, Marta Camprubí-Rimblas, Antonio Artigas
Hypercapnia is developed in patients with acute and/or chronic respiratory conditions. Clinical data concerning hypercapnia and respiratory infections interaction is limited.Currently, the relation...
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Do all patients with cancer thrombosis have the same risk of bleeding and recurrence? Particularities of lung cancer Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2024-03-15 Laurent Bertoletti, Ludovic Lafaie, Thibault LeConte, Anne-Laure Desage, Bastien Petit, Lutfi Ozturk, Sandrine Accassat, Pauline Corbaux, Géraldine Poenou
Published in Expert Review of Respiratory Medicine (Just accepted, 2024)
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Interstitial lung diseases: never forget to think about it in primary care Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2024-03-14 Guadalupe Bermudo, Miguel Roman-Rodriguez, Maria Molina-Molina
Published in Expert Review of Respiratory Medicine (Just accepted, 2024)
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So we now have RSV vaccines. What’s our next steps? Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2024-03-14 Joseph M. Blondeau
Published in Expert Review of Respiratory Medicine (Just accepted, 2024)
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Advances in lung cancer surgery: the role of segmentectomy in early–stage management Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2024-03-08 Luca Bertolaccini, Monica Casiraghi, Clarissa Uslenghi, Cristina Diotti, Antonio Mazzella, Giovanni Caffarena, Lorenzo Spaggiari
The evolving landscape of surgical interventions for early-stage non-small cell lung cancer (NSCLC) necessitates a reassessment of the traditional gold standard of lobectomy versus emerging subloba...
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Factors associated with anxiety and depression among patients with chronic obstructive pulmonary disease Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2024-03-07 Anan S. Jarab, Walid A. AlQerem, Shrouq R. Abu Heshmeh, Yazid N Al Hamarneh, Salah Aburuz, Judith Eberhardt
This study investigated factors associated with anxiety and depression in COPD outpatients.A cross-sectional study of 702 COPD outpatients from two major Jordanian hospitals using the Hospital Anxi...
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Diversity in pulmonary rehabilitation clinical trials: a systematic review of the literature Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2024-02-27 Sunaina Chopra, Shivani Rana, Reenal Patel, Tessa Hamilton, Alyssa Dalip, Param Malhi, Pat G. Camp
Underrepresentation of minority groups in clinical trials may hinder the potential benefits of pulmonary rehabilitation (PR) programs for individuals with chronic obstructive pulmonary disease (COP...
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Why don’t anti-inflammatories work in cystic fibrosis? Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2024-02-22 Michelle Casey, Nicholas J Simmonds
Published in Expert Review of Respiratory Medicine (Just accepted, 2024)
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Bayesian or frequentist: there is no question when comparing single-inhaler triple therapies via network meta-analysis. Focus on fluticasone furoate/umeclidinium/vilanterol fixed-dose combination in chronic obstructive pulmonary disease Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2024-02-16 Luigino Calzetta, Paola Rogliani
Single-inhaler triple therapies (SITTs) have never been directly compared in randomized controlled trials (RCTs) in chronic obstructive pulmonary disease (COPD). Cochrane recommends the Bayesian ap...
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The ageing of Cystic Fibrosis patients with new modulators: current gaps and challenges Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2024-02-12 Almudena Felipe Montiel, Antonio Álvarez Fernández, Letizia Traversi, Eva Polverino
Published in Expert Review of Respiratory Medicine (Vol. 17, No. 12, 2023)
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First-line immunotherapy in non-small cell lung cancer: how to select and where to go Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2024-02-09 Andrea Mogavero, Ornella Cantale, Veronica Mollica, Shobana Anpalakhan, Alfredo Addeo, Giannis Mountzios, Alex Friedlaender, Ravindran Kanesvaran, Silvia Novello, Giuseppe Luigi Banna
Immunotherapy (IO) has established a new milestone in lung cancer treatment. Several registrational studies have approved immune checkpoint inhibitors (ICIs) in different settings, including the me...
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Mild asthma is not mild: risk factors and predictive biomarkers for severe acute exacerbations and progression in mild asthma Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2024-02-06 Lingling Wang, Ling Zhou, Pengdou Zheng, Zhenyu Mao, Huiguo Liu
Asthma is a common chronic respiratory disease characterized by chronic airway inflammation, airway hyperresponsiveness, reversible airflow limitation, and airway remodeling. Mild asthma is the mos...
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Co-existence of OSA and respiratory diseases and the influence of gender Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2024-02-06 Sophia Schiza, Esther I. Schwarz, Maria R. Bonsignore, Walter T. McNicholas, Athanasia Pataka, Izolde Bouloukaki
Sleep-disordered breathing (SDB), especially obstructive sleep apnea (OSA), is commonly associated with respiratory diseases, such as COPD, asthma and interstitial lung disease.This narrative revie...
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A three-gene random forest model for diagnosing idiopathic pulmonary fibrosis based on circadian rhythm-related genes in lung tissue Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2024-01-31 Jie He, Jun Hu, Hairong Liu
The disorder of circadian rhythm could be a key factor mediating fibrotic lung disease Therefore, our study aims to determine the diagnostic value of circadian rhythm-related genes (CRRGs) in IPF.W...
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Impact of indoor environment on children’s pulmonary health Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2024-01-31 Jared Murphy, Ramiyya Tharumakunarajah, Karl A. Holden, Charlotte King, Alice R. Lee, Katie Rose, Daniel B. Hawcutt, Ian P. Sinha
A child’s living environment has a significant impact on their respiratory health, with exposure to poor indoor air quality (IAQ) contributing to potentially lifelong respiratory morbidity. These e...
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Demystification of artificial intelligence for respiratory clinicians managing patients with obstructive lung diseases Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2024-01-25 Joana Antão, Jeroen de Mast, Alda Marques, Frits M.E. Franssen, Martijn A. Spruit, Qichen Deng
Asthma and chronic obstructive pulmonary disease (COPD) are leading causes of morbidity and mortality worldwide. Despite all available diagnostics and treatments, these conditions pose a significan...
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The impact of air pollution on asthma: clinical outcomes, current epidemiology, and health disparities Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2024-01-25 Ryan J. Fiter, Lila J. Murphy, Michelle N. Gong, Krystal L. Cleven
Air pollution has been shown to have a significant impact on morbidity and mortality of respiratory illnesses including asthma.Outdoor air pollution consists of a mixture of individual pollutants i...
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Genetic polymorphisms in CYP2B6 may be associated with lung cancer risk in the Chinese Han population Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2024-01-04 Xiaoya Ma, Xufeng Zang, Leteng Yang, Wenqian Zhou, Yujie Li, Jie Wei, Jinping Guo, Junhui Han, Jing Liang, Tianbo Jin
Our study aimed to elucidate the association between single nucleotide polymorphisms (SNPs) in CYP2B6 gene and susceptibility to lung cancer (LC).Five SNPs in CYP2B6 were genotyped in Chinese Han p...
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Mechanisms and management of cough in interstitial lung disease Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-30 Ameer Z. Rasheed, Mark L. Metersky, Fatima Ghazal
Many patients with interstitial lung diseases (ILDs), especially fibrotic ILDs, experience chronic cough. It negatively impacts both physical and psychological well-being. Effective treatment optio...
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Interventional bronchoscopy in pediatric pulmonary tuberculosis Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-28 Pierre Goussard, Ernst Eber, Shyam Venkatakrishna, Lisa Frigati, Leonore Greybe, Jacques Janson, Pawel Schubert, Savvas Andronikou
Lymphobronchial tuberculosis (TB) is common in children with primary TB and enlarged lymph nodes can cause airway compression of the large airways. If not treated correctly, airway compression can ...
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Indications and evidence for domiciliary noninvasive ventilation Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-27 Anita Saigal, Amar J Shah, Swapna Mandal
Home noninvasive ventilation (HNIV) has expanded globally, with a greater evidence base for its use. HNIV improves multiple patient related outcomes in patients with chronic hypercapnic respiratory...
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Modified STOP-bang questionnaire incorporating morning dry mouth and BMI adjustment in China: a retrospective study of 590 patients Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-26 Xiaoyu Ma, Cheng Zhang, Liping Feng, Yane Shen, Jing Ma, Guangfa Wang
Morning dry mouth (MDM) is a common symptom of Obstructive Sleep Apnea (OSA) yet current OSA screening tools overlook it.To enhance the specificity of the Stop-Bang questionnaire (SBQ) by adding an...
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Pulmonary embolism: a practical approach to update risk stratification and treatment decisions based on the guidelines Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-26 María Barca-Hernando, Luis Jara-Palomares
Pulmonary embolism (PE) is a prevalent condition with a substantial morbi-mortality worldwide. Proper risk stratification of PE is essential for identifying the most suitable therapeutic strategy a...
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Association between depression and COPD: results from the NHANES 2013–2018 and a bidirectional Mendelian randomization analysis Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-26 Bi Ran, Yutian Zhang, Yanqiu Wu, Fuqiang Wen
Observational studies showed a bidirectional association between depression and chronic obstructive pulmonary disease (COPD). However, it is unclear whether the observed association is causal. Thus...
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Diagnosis of pleural tuberculosis by multi-targeted loop-mediated isothermal amplification assay based on SYBR Green I reaction: comparison with GeneXpert® MTB/RIF assay Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-26 Aishwarya Soni, Bhawna Dahiya, Abhishek Sheoran, Vipul Kumar, Astha Guliani, Nitin Kumar, Vikas Hooda, Aparna Yadav, Kiran Nehra, Promod K. Mehta
Diagnosis of pleural tuberculosis (TB) is tedious owing to its close resemblance with malignant pleural effusion and sparse bacterial load in clinical specimens. There is an immediate need to desig...
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Differential COVID-19 preventive behaviors among Asian subgroups in the United States Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-26 YuJing Wu, Ahan Shi, Laite Chen, Dejun Su
Given the observed within-Asian disparity in COVID-19 incidence, we aimed to explore the differential preventive behaviors among Asian subgroups in the United States.Based on data from the Asian su...
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Gene signatures in U-BIOPRED severe asthma for molecular phenotyping and precision medicine: time for clinical use Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-26 Nazanin Kermani, Ali Versi, Aurore Gay, Jelmer Vlasma, Akshaya Keerthi Saikumar Jayalatha, Gerard H. Koppelman, Martijn Nawijn, Alen Faiz, Maarten van den Berge, Ian M. Adcock, Kian Fan Chung
The use and generation of gene signatures have been established as a method to define molecular endotypes in complex diseases such as severe asthma. Bioinformatic approaches have now been applied t...
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Recommendations on scuba diving in Birt-Hogg-Dubé syndrome Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-26 L. van Riel, RA. van Hulst, L. van Hest, RJA. van Moorselaar, BG. Boerrigter, SM. Franken, RMF. Wolthuis, HJ. Dubbink, SJ. Marciniak, N. Gupta, I. van de Beek, AC. Houweling
Although very uncommon, severe injury and death can occur during scuba diving. One of the main causes of scuba diving fatalities is pulmonary barotrauma due to significant changes in ambient pressu...
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Progress in genome-inspired treatment decisions for multifocal lung adenocarcinoma Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-26 Chelsea L. Powell, Sahar A. Saddoughi, Dennis A. Wigle
Multifocal lung adenocarcinoma (MFLA) is becoming increasingly recognized as a distinct subset of lung cancer, with unique biology, disease course, and treatment outcomes. While definitions remain ...
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Multidisciplinary bronchopulmonary dysplasia care Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-26 Audrey N. Miller, Edward G. Shepherd, George El-Ferzli, Leif D. Nelin
Bronchopulmonary dysplasia (BPD) is a chronic respiratory disease in neonates and infants, which often presents with multisystem organ involvement, co-morbidities, and prolonged hospital stays. The...
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Demystifying controversies in preschool wheeze Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-26 Frank M Smith, Sejal Saglani
Wheezing disorders in preschool children are common. Current treatment approaches assume all preschool wheezers are the same and will respond to a short course of oral corticosteroids (OCS) during ...
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Role of radiation in oligometastases and oligoprogression in metastatic non-small cell lung cancer: consensus and controversy Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-26 Abhishek Kumar, Joseph K Salama
The oligometastatic state in non-small cell lung cancer (NSCLC) has recently become well-established. However, the specific definition of oligometastases remains unclear. Several smaller randomized...
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A narrative review of nontuberculous mycobacterial pulmonary disease: microbiology, epidemiology, diagnosis, and management challenges Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-26 Kamal A. Hamed, Glenn Tillotson
Nontuberculous mycobacteria (NTM) are a diverse group of mycobacterial species that are ubiquitous in the environment. They are opportunistic pathogens that can cause a range of diseases, especiall...
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Effects of short-term air pollution exposure on symptoms development in the course of idiopathic pulmonary fibrosis Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-26 Konstantina Dimakopoulou, Ioannis Tomos, Effrosyni D. Manali, Spyros A. Papiris, Anna Karakatsani
Lately a potential detrimental effect of air pollution to idiopathic pulmonary fibrosis emerged. We aimed to assess the effects of short-term air pollution exposure to the clinical course of IPF.IP...
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Correction Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-20
Published in Expert Review of Respiratory Medicine (Ahead of Print, 2023)
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High risks adverse events associated with usage of aspirin in chronic obstructive pulmonary disease Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-19 Xiaohua Li, Bin Dai, Qingbing Han, Yanqiu Wu, Bi Ran, Tao Wang, Fuqiang Wen, Jun Chen
Despite potential benefits and widespread prescription of aspirin among chronic obstructive pulmonary disease (COPD) patients, limited research has investigated its adverse effects (AEs) in COPD po...
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Effects of cardiorespiratory rehabilitation program on submaximal exercise in patients with long-COVID-19 conditions: a systematic review of randomized controlled trials and recommendations for future studies Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-12-14 Amine Ghram, Imed Latiri, Jabeur Methnani, Amine Souissi, Wafa Benzarti, Emna Toulgui, Helmi Ben Saad
Long-COVID-19 patients (LC19Ps) often experience cardiovascular and respiratory complications. Cardiorespiratory rehabilitation programs (CRRPs) have emerged as promising interventions to enhance e...
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Extracorporeal membrane oxygenation for cardiac arrest: what, when, why, and how Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-11-29 Matthew Brandorff, Clark G. Owyang, Joseph E. Tonna
Extracorporeal membrane oxygenation (ECMO) facilitated resuscitation was first described in the 1960s, but only recently garnered increased attention with large observational studies and randomized...
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Evaluation and management of persistent air leak Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-11-24 Garret Duron, Elliot Backer, David Feller-Kopman
Persistent air leaks (PAL) represent a challenging clinical problem for which there is not a clear consensus to guide optimal management. PAL is associated with significant morbidity, mortality, an...
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Interactions between calcium regulatory pathways and mechanosensitive channels in airways Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-11-24 Yang Yao, Niyati A Borkar, Mengning Zheng, Shengyu Wang, Christina M Pabelick, Elizabeth R Vogel, YS Prakash
Asthma is a chronic lung disease influenced by environmental and inflammatory triggers and involving complex signaling pathways across resident airway cells such as epithelium, airway smooth muscle...
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Spirometry in atrial fibrillation: what’s the catch? Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-11-24 Anne E Ioannides, Upasana Tayal, Jennifer K Quint
People with COPD rarely have COPD alone, and the commonest co-morbidities occurring with COPD are cardiovascular. Whilst multiple studies have explored the association between major cardiovascular ...
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Extracorporeal membrane oxygenation for COVID-19 and influenza associated acute respiratory distress syndrome: a systematic review Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-11-24 Lian Wang, Dongguang Wang, Tianli Zhang, Ying He, Hong Fan, Yonggang Zhang
Extracorporeal membrane oxygenation (ECMO) has been used extensively for H1N1 influenza and coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome (ARDS) to improve gas exc...
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Time to treat the climate and nature crisis as one indivisible global health emergency Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-11-24 Kamran Abbasi, Parveen Ali, Virginia Barbour, Thomas Benfield, Kirsten Bibbins-Domingo, Gregory E. Erhabor, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Robert Mash, Peush Sahni, Wadeia Mohammad Sharief, Paul Yonga, Chris Zielinski
Published in Expert Review of Respiratory Medicine (Vol. 17, No. 10, 2023)
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Phenotype and endotype based treatment of preschool wheeze Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-11-24 Sormeh Salehian, Louise Fleming, Sejal Saglani, Adnan Custovic
Preschool wheeze (PSW) is a significant public health issue, with a high presentation rate to emergency departments, recurrent symptoms, and severe exacerbations. A heterogenous condition, PSW comp...
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Pathogenesis and management of emphysema in people with HIV Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-11-24 Jonah S. Kreniske, Robert J. Kaner, Marshall J. Glesby
Since early in the HIV epidemic, emphysema has been identified among people with HIV (PWH) and has been associated with increased mortality. Smoking cessation is key to risk reduction. Health maint...
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Exploring the complex relationship between the lung microbiome and ventilator-associated pneumonia Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-11-24 Ingrid G. Bustos, Ignacio Martín-Loeches, Alejandro Acosta-González, Sanjay H. Chotirmall, Robert P. Dickson, Luis Felipe Reyes
Understanding the presence and function of a diverse lung microbiome in acute lung infections, particularly ventilator-associated pneumonia (VAP), is still limited, evidencing significant gaps in o...
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The potential clinical value of pairing procalcitonin and lung ultrasonography to guide antibiotic therapy in patients with community-acquired pneumonia: a narrative review Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-11-24 Cécile Bessat, Noémie Boillat-Blanco, Werner C. Albrich
Lower respiratory tract infections (LRTIs) are among the most frequent infections and are prone to inappropriate antibiotic treatments. This results from a limited accuracy of diagnostic tools in i...
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Endobronchial ultrasound with a guide sheath during bronchoscopy for peripheral pulmonary lesions Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-11-24 Yuta Takashima, Masahide Oki
Radial probe endobronchial ultrasound (rEBUS) improves the diagnostic yield of peripheral pulmonary lesions (PPLs). A notable methodological limitation of rEBUS is that it does not provide real-tim...
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Adherence to inhaled antibiotics in people with cystic fibrosis: insights from a virtual patient advisory board Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-11-24 Simone Gambazza, Valerie Storms, Vinay Purohit
Chronic airway infection by Pseudomonas aeruginosa significantly impacts the health of people with cystic fibrosis (PwCF), presenting complex treatment challenges.To gain insights into PwCF’s exper...
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Persistent respiratory symptoms associated with post-Covid condition (Long Covid) in children: a systematic review and analysis of current gaps and future perspectives Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-11-24 Laura Martino, Rosa Morello, Cristina De Rose, Danilo Buonsenso
There is increasing evidence that also children can develop Long Covid. However, there are no specific reviews providing a clear description of reported respiratory symptoms and potential diagnosti...
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Stratification of patients with KRAS-mutated advanced non-small cell lung cancer: improving prognostics Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-10-27 Yuda Zhang, Fanxu Zeng, Shixuan Peng, Yangqian Chen, Wenjuan Jiang, Zhan Wang, Li Deng, Zhe Huang, Haoyue Qin, Huan Yan, Xing Zhang, Lin Zhang, Nong Yang, Qian Gong, Liang Zeng, Yongchang Zhang
KRAS is the most frequently mutated oncogene in cancer and encodes a key signaling protein in tumors. Due to its high affinity for GTP and the lack of a large binding pocket that allosteric inhibit...
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Should we be screening for COPD? – looking through the lens of lung cancer screening Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-10-27 Robert P. Young, Raewyn J. Scott
In May 2022, the US Preventive Services Task Force published their recommendation against screening for chronic obstructive pulmonary disease (COPD) in asymptomatic adults. However, we argue the ro...
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Clinical predictors and outcomes of pulmonary infarction in patients with central pulmonary embolism Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-10-27 Jose Manuel Martinez Manzano, Kevin Bryan Lo, Omar Cantu-Martinez, Long Nguyen, Brenda Chiang, Simone A. Jarrett, Sahana Tito, Alexander Prendergast, Maria A. Planchart Ferretto, Willy Roque, Ammaar Wattoo, Zurab Azmaiparashvili, Sadia Benzaquen
Given the heterogeneity of predisposing factors associated with pulmonary infarction (PI) and the lack of clinically relevant outcomes among patients with acute pulmonary embolism (PE) complicated ...
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What to do after immune-checkpoint inhibitors failure in advanced non-small cell lung cancer: an expert opinion and review Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-10-27 Alberto Giuseppe Agostara, Laura Roazzi, Federica Villa, Rebecca Romano’, Daniele Piscazzi, Francesca Martinelli, Gabriele Ciarlo, Sara Oresti, Francesca Travaglini, Alessandro Marando, Andrea Sartore-Bianchi, Laura Giannetta, Giulio Cerea, Salvatore Siena, Elio Gregory Pizzutilo, Diego Signorelli
Immune-checkpoint inhibitors (IO) have significantly improved outcomes of patients with non-oncogene-addicted non-small cell lung cancer (NSCLC), becoming the first-line agents for advanced disease...
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Is there cardiac autonomic dysfunction in children and adolescents with exercise-induced bronchospasm? Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-10-27 Polyanna Guerra Chaves Quirino, José Ângelo Rizzo, Steve Hunter, Edil de Albuquerque Rodrigues Filho, Emanuel Sarinho, Camila Matias de Almeida Santos, Decio Medeiros, Emilia Chagas Costa, Alexandre Sérgio Silva, Breno Quintella Farah, Marco Aurélio de Valois Correia Júnior
The pulmonary impairment in patients with bronchoconstriction induced by eucapnic voluntary hyperpnea(EVH) goes beyond the respiratory system, also impairing autonomic nervous modulation. This stud...
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Thoracic ultrasound-guided real-time pleural biopsy in the diagnosis of pleural diseases: a systematic review and meta-analysis Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-10-27 Qin Zhang, Ming-Ming Deng, Xue-Lian Li, Ye Lu, Gang Hou
Real-time thoracic ultrasound-guided pleural biopsy (TUSPB) is an important diagnostic method for pleural diseases. Traditional two-dimensional thoracic ultrasound, as well as newly developed contr...
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Epithelial alarmins: a new target to treat chronic respiratory diseases Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-10-27 Denislava Nedeva, Krzysztof Kowal, Stefan Mihaicuta, Guillermo Guidos Fogelbach, Paschalis Steiropoulos, Herberto Jose Chong-Neto, Angelica Tiotiu
In response to injury, epithelial cells release alarmins including thymic stromal lymphopoietin (TSLP), high mobility group-box-1 (HMGB1), interleukin (IL)-33 and −25 that can initiate innate immun...
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Interstitial lung abnormality in COPD is associated with higher prevalence of antinuclear antibody Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-09-12 Yujia Liu, Yanwen Jiang, Yongchang Sun
To investigate whether the prevalence of positive ANA was increased in COPD with interstitial lung abnormality (ILA).Patients with COPD from 1 September, 2019 to 31 August, 2022 were consecutively ...
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Pneumothorax, pneumomediastinum, and subcutaneous emphysema in hospitalized COVID-19 patients: incidence, clinical characteristics, and outcomes Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-09-11 Aleksandra Murawska Baptista, Jorge Sinclair De Frías, Trisha Singh, Ananya Vasudhar, Jacob Guzzino, Waheed Khalili, Aysun Tekin, Vikas Bansal, Rahul Kashyap, William J. Joyce, Patricia A. Lewis, Devang Sanghavi, Tatjana Gavrancic, Pablo Moreno Franco
Limited data is available on the incidence and outcomes of pneumothorax (PTX), pneumomediastinum (PNM), and subcutaneous emphysema (SCE) in COVID-19 patients. This study aimed to investigate the ch...
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The value of perioperative physical activity in older patients undergoing surgery for lung cancer Expert Rev. Respir. Med. (IF 3.9) Pub Date : 2023-09-11 Dan J. Raz, Jae Y. Kim, Loretta Erhunwmunesee, Sherry Hite, Gouri Varatkar, Virginia Sun
With a median age at diagnosis of 70, lung cancer represents an enormous public health problem among older Americans. An estimated 19,000 people age 65 and older undergo lung cancer surgery annuall...