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The most common pulmonary diseases length of stay, and characteristics of patients admitted to pulmonary service. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-07-19 Hamdan Al-Jahdali,Anwar Ahmed,Abdullah Al-Harbi,Ayaz Khan,Majed ALGamedi,Sami Alyami,Hajar Hayyan,Mohamed Al-Moamary,Ahmed Almuttari
BACKGROUND Although chronic respiratory diseases are prevalent in Saudi Arabia, there are limited data on the patient burden and associated factors. The aim of this study is to identify the chronic respiratory diseases frequently admitted to pulmonary services and to determine the patient's characteristics, associated comorbidities readmission rate, and reason for a more extended stay in hospital.
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Increased expiratory flows identify early interstitial lung disease. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-07-19 Sami Mohammed Alyami,Onofre Moran-Mendoza
BACKGROUND Most interstitial lung diseases (ILDs) manifest with a restrictive ventilatory defect as the common physiologic abnormality. Low carbon monoxide diffusing capacity (Dlco) is considered to be the earliest abnormality on pulmonary function tests (PFTs) in patients with ILD. However, its measurement requires complex and expensive equipment. Our study aimed to assess if high expiratory flows
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The impact of pulmonary cachexia on inpatient outcomes: A national study. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-07-19 Mohamad Alhoda Mohamad Alahmad,Cheryl A Gibson
BACKGROUND Cachexia has been associated with chronic lung disease (pulmonary cachexia syndrome), which is associated with increased mortality. However, studies that looked into this association was relatively small, and national level data are lacking. Herein, we aim to study the association between chronic obstructive lung disease (COPD) and cachexia. RESEARCH QUESTION Do patients with COPD and cachexia
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Prevalence of acute infection in adults with asthma exacerbation: A systematic review and meta-analysis. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-07-19 Xi Chen,Pingan Zhang,Yanliang Ma
BACKGROUND Acute respiratory infections are a major trigger of asthma exacerbations. This study sought to estimate the overall proportion of viruses, atypical pathogens, and bacteria detected in adults with asthma exacerbations. METHODS PubMed, EMBASE, and Cochrane Library databases and all related studies from the reviews and references were searched from inception to February 13, 2020. Two authors
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Case of uncontrolled asthma with Ceriporia lacerata-related broncholithiasis. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-05-16 Chihiro Nakano,Norio Kodaka,Toshiaki Oharaseki,Hiroto Matsuse
An 81-year-old Japanese male patient was treated for asthma. He complained of persistent cough and wheezing. Chest computed tomography scan revealed atelectasis in the right middle lobe. Fiberoptic bronchoscopy was performed. Results showed a calcified stone with filamentous fungi with septa in the right middle lobe bronchus, which was subsequently removed. Ceriporia lacerata was detected repeatedly
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COVID-19-associated pulmonary aspergillosis in patients with severe SARS-CoV-2 infection: A single-center observational study from Greece. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-05-16 Konstantinos Ouranos,Kalliopi Tsakiri,Eleni Massa,Vassiliki Dourliou,Christina Mouratidou,Stella Soundoulounaki,Eleni Mouloudi
INTRODUCTION COVID-19-associated pulmonary aspergillosis (CAPA) is a serious complication affecting patients with severe SARS-CoV-2 infection, and is associated with increased mortality. OBJECTIVE The objective of this study was to investigate potential risk factors, and to estimate the incidence and mortality in patients diagnosed with CAPA. METHODS A single-center retrospective observational study
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The impact of unsupervised and unconsented switch of inhalers in patients with controlled asthma - A targeted literature review. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-05-16 Amr S Albanna,Mohammed Alhajji,Waleed Alsowayan,Mohamed Hany Soliman
Inhaler combination formulations consisting of an inhaled corticosteroid (ICS) (fluticasone propionate) and a long-acting β2 agonist (salmeterol xinafoate) are indicated as maintenance treatments for patients with asthma and/or for selected patients with chronic obstructive pulmonary disease. The emergence of generic equivalents to branded inhalers is expected to offer economic edge/savings; however
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Nonuniform references style: A fundamental reason for citation error. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-05-16 Sanjay Singhal,Abhilasha Motghare,Mrinalini Verma
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The effect of the COVID-19 pandemic on hospital admissions and outpatient visits in Ontario, Canada. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-04-25 Steven Habbous,Anna Lambrinos,Stephen Petersen,Erik Hellsten
INTRODUCTION The wave-over-wave effect of the COVID-19 pandemic on hospital visits for non-COVID-19-related diagnoses in Ontario, Canada remains unknown. METHODS We compared the rates of acute care hospitalizations (Discharge Abstract Database), emergency department (ED) visits, and day surgery visits (National Ambulatory Care Reporting System) during the first five "waves" of Ontario's COVID-19 pandemic
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Risk factors predicting disease severity and mortality in coronavirus disease 2019 Saudi Arabian patients. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-04-25 Wala M Al Balwi,Nouf AlGhamdi,Reem Alshahrani,Ihssan H Abdelrahman,Sami Mahmoud,Ali Al-Hamad,Salma Al Hamzah,Fahad Al Jraid,Maha Al Turki,Mohammed A Al Balwi
CONTEXT Coronavirus disease 2019 (COVID-19) became a global pandemic that may be associated with significant associated risk factors. AIMS The aim of this study was to evaluate the factors predisposing risk to death in COVID-19 patients. SETTINGS AND DESIGN This is a retrospective study that presents the demographic, clinical presentation, and laboratory findings on our patients to determine risk factors
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Management of pulmonary nodules in women with pregnant intention: A review with perspective. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-04-25 Jiaqi Zhang,Kun Tang,Lei Liu,Chao Guo,Ke Zhao,Shanqing Li
The process for the management of pulmonary nodules in women with pregnant intention remains a challenge. There was a certain proportion of targeted female patients with high-risk lung cancer, and anxiety for suspicious lung cancer in early stage also exists. A comprehensive review of hereditary of lung cancer, effects of sexual hormone on lung cancer, natural history of pulmonary nodules, and computed
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Characteristics of pleural effusion due to amyloidosis. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-04-25 Cristina Pou,Lucía Ferreiro,Juan Suárez-Antelo,Antonio Golpe,José M Álvarez-Dobaño,María Elena Toubes,Adriana Lama,Nuria Rodríguez-Núñez,Jorge Ricoy,Carlos Rábade,Tamara Lourido,Luis Valdés
The characteristics of patients with pleural amyloidosis (PA) are poorly known. A systematic review was performed of studies reporting clinical findings, pleural fluid (PF) characteristics, and the most effective treatment of PA. Case descriptions and retrospective studies were included. The review included 95 studies with a total sample of 196 patients. The mean age was 63 years, male/female ratio
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The prevalence of rapid eye movement-related obstructive sleep apnea in a sample of Saudi population. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-04-25 Sultan Qanash,Hani Mufti,Faris Alhejaili,Faisal Al-Husayni,Ghufran Bukhari,Shatha Bazhair,Ghadi Alansari,Alaa Aldeibani,Dimah Balkhi,Yara Alhjrsy,Shahad Albadani,Malak Alamoudi,Siraj Wali
BACKGROUND This study aimed to estimate the prevalence of rapid eye movement-related obstructive sleep apnea (REMrOSA) using common definitions. METHODS This was a retrospective cohort study that used three sets of criteria to identify patients with REMrOSA. These criteria were defined as strict, intermediate, and lenient depending on the apnea-hypopnea index (AHI), AHI during REM sleep/(AHI during
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Prospective analysis of the physiological changes caused by prolonged use of N95-type masks. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-04-25 Melis E Demirag,Mustafa Akyil,Merve Karasal,Serkan Bayram,Serda Kanbur Metin,Fatma A Tokgoz,Volkan Baysungur,Serdar Evman
INTRODUCTION The clinical and physiological effects of long-duration use of N95-type masks without ventilation valves, on health-care workers during the coronavirus disease-2019 (COVID-19) pandemic, were evaluated. METHODS All volunteering personnel working in operating theater or intensive care unit, using nonventilated N95 type respiratory masks, minimum for a 2-h noninterrupted duration were observed
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A survival analysis of idiopathic pulmonary fibrosis in the context of antifibrotic therapy in Saudi Arabia. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-04-25 Mohammed Ayaz Khan,Basma Al Ghamdi,Mohammed Alhamadi,Rajkumar Rajendram,Sami Alyami,Majed Al-Gamedi,Abdullah Al-Harbi,Hamdan Al-Jahdali
BACKGROUND The prognosis of idiopathic pulmonary fibrosis (IPF) can be predicted by the gender, age, and physiology (GAP) index. However, antifibrotic therapy (i.e., nintedanib and pirfenidone) may improve survival. AIMS This study aimed to compare the outcomes of antifibrotic-treated IPF with the survival predicted by the GAP index. METHODS A retrospective cohort study was conducted from March 2014
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Increased airway resistance among exclusive waterpipe smokers detected using impulse oscillometry. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-01-25 Hassan A Chami,Nourhan Houjeij,Maha Makki,Lina Itani,Hani Tamim,Ahmad Al Mulla,Bartolome Celli,Salah Zeineldine
INTRODUCTION Waterpipe smoking is increasing in popularity, yet the evidence implicating waterpipe smoking in lung disease is limited. We hypothesized that impulse oscillometry (IOS) would detect airway abnormalities in waterpipe smokers (WPS). METHODS We studied 210 participants, 40 years or older, from the community, of whom 92 were exclusive WPS and 118 were never-smokers. Waterpipe smoking history
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Nintedanib and pirfenidone for idiopathic pulmonary fibrosis in King Abdulaziz Medical City, Riyadh: Real-life data. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-01-25 Mohammed Ayaz Khan,Nahed Sherbini,Sami Alyami,Abdullah Al-Harbi,Majed Al-Ghamdi,Suliman Alrajhi,Rajkumar Rajendram,Hamdan Al-Jahdali
BACKGROUND Idiopathic pulmonary fibrosis (IPF) is a chronic progressive age-related lung disease causing relentless fibrosis of the lung parenchyma. Currently, pirfenidone and nintedanib are the two antifibrotic drugs, approved for the treatment of IPF. Both are shown to slow progression by preserving lung functions from rapid decline compared to a placebo. We are reporting a real-life patient experience
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The implications of Vitamin E acetate in E-cigarette, or vaping, product use-associated lung injury. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-01-25 Brian Soto,Louis Costanzo,Anoop Puskoor,Nada Akkari,Patrick Geraghty
In the summer of 2019, a cluster of cases were observed with users of battery-operated or superheating devices presenting with multiple symptoms, such as dyspnea, cough, fever, constitutional symptoms, gastrointestinal upset, and hemoptysis, that is now termed e-cigarette, or vaping, product use-associated lung injury (EVALI). The Centers for Disease Control and Prevention reported 2807 cases within
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Optimal positive airway pressure requirement and polysomnography indices of obstructive sleep apnea severity in the Saudi population. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-01-25 Ahmad A Bamagoos,Shahad A Alshaynawi,Atheer S Gari,Atheer M Badawi,Mudhawi H Alhiniah,Asma A Alshahrani,Renad R Rajab,Reem K Bahaj,Faris Alhejaili,Siraj O Wali
CONTEXT Positive airway pressure (PAP) is the first-line therapy for obstructive sleep apnea (OSA). Overnight PAP titration for determining optimal PAP requirements is expensive and often inconvenient. Prediction of optimal PAP requirements from diagnostic polysomnography via mathematical equations is possible but variable across populations. AIMS We aimed to (1) determine the optimal PAP requirement
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Application of single-port laparoscopic retrograde gastric mobilization during McKeown esophagectomy for esophageal cancer. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-01-25 Bo Liu,Xu Li,Min-Jie Yu,Jin-Bao Xie,Guo-Liang Liao,Ming-Lian Qiu
BACKGROUND As a novel alternative to the conventional minimally invasive esophagectomy (MIE) to treat esophageal cancer, single-port laparoscopic retrograde three-step gastric mobilization (SLRM) for esophageal reconstruction during MIE to treat esophageal cancer was attempted in our department. The aim of the present study was to explore the preliminary clinical outcomes and feasibility of this innovative
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Measurement of the awareness of venous thromboembolism in the Saudi population. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-01-25 Ali Alaklabi,Shouq Mohammed AlNujaim,Sarah Mohammed Alghaihab,Sadeem Ahmed AlDakhil,Obeid Mohammed AlKethami,Rajkumar Rajendram
BACKGROUND Venous thromboembolism (VTE) causes significant morbidity and mortality. International studies have suggested poor public awareness of VTE, with a few data from Saudi Arabia. The aim of this study was to investigate the knowledge and awareness of VTE in the Saudi population. Awareness of other important diseases was also investigated to allow contextualization. METHODS A cross-sectional
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General rehabilitation for the Post-COVID-19 condition: A narrative review. Ann. Thorac. Med. (IF 2.3) Pub Date : 2023-01-25 Dian Marta Sari,Laurentia Cindy Gani Wijaya
COVID-19 significantly impacts the acute phase or the period after being infected by severe acute respiratory syndrome coronavirus-2. Studies have shown it has affected multiorgan and needs continuous care by a multidisciplinary team. Nowadays, guidance is required to assist the recovery process of survivors who reported at least one symptom as a residual effect. This study aims to describe the rehabilitation
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Incidence and profile of severe exacerbations of chronic obstructive pulmonary disease due to biomass smoke or tobacco. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-10-07 Rafael Golpe,Nagore Blanco-Cid,David Dacal-Rivas,Irene Martín-Robles,Iria Veiga,Indhira Guzmán-Peralta,Olalla Castro-Añón,Luis A Pérez-de-Llano
INTRODUCTION AND OBJECTIVES Stable chronic obstructive pulmonary disease (COPD) caused by biomass smoke (B-COPD) has some differences from tobacco-induced-COPD (T-COPD), but acute exacerbations (AECOPD) have not been well characterized in B-COPD. OBJECTIVE To compare the incidence, characteristics and outcomes of AECOPD in B-COPD with those of T-COPD. METHODS A retrospective observational study that
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Acute chest syndrome in pediatric sickle cell disease: A 19-year tertiary center experience. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-10-07 Abdullah A Yousef,Hwazen A Shash,Ali N Almajid,Ammar A Binammar,Hamza Ali Almusabeh,Hassan M Alshaqaq,Mohammad H Al-Qahtani,Waleed H Albuali
INTRODUCTION The most common cause of death among sickle cell disease (SCD) patients is acute chest syndrome (ACS). Since SCD is a common condition in the Eastern province of the Kingdom of Saudi Arabia (KSA), we aimed to provide a detailed description of the clinical characteristics and ACS management. METHODS We retrospectively studied pediatric (<14 years) patients with SCD diagnosis who were admitted
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Clinical characteristics and risk factors for mortality of hospitalized cancer patients with COVID-2019 in Mecca, Saudi Arabia. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-10-07 Nabil Ghaleb,Adeeb Bulkhi,Eid Al-Qurashi,Abdelfattah Touman,Ahmad Aldobyany,Rajaa Z Alsaggaf,Hanan Mabar,Noureen H Murtaza,Ammar Rajab
BACKGROUND Cancer patients are particularly vulnerable during the coronavirus disease 2019 (COVID-19) pandemic. This study aimed to evaluate clinical characteristics and mortality among cancer patients with COVID-19. METHODS This retrospective, observational cohort study included 53 patients with a malignancy and reverse-transcription polymerase chain reaction-confirmed severe acute respiratory syndrome
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Sodium bicarbonate buffer for weaning from venovenous extracorporeal membrane oxygenation in patients with hypercapnic respiratory failure and acute renal failure. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-10-07 Sua Kim,Jinwook Hwang,Je Hyeong Kim
Although the routine use of alkali buffer is not recommended in patients with respiratory acidosis, some patients may benefit from its administration. A 42-year-old man was treated with venovenous extracorporeal membrane oxygenation (VV-ECMO) and continuous venovenous hemodiafiltration (CVVHDF) due to necrotizing pneumonia and emphysematous cystitis with Klebsiella pneumoniae. Although the sweep gas
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Comparing the characteristics of positional and nonpositional sleep apnea patients among the Jordanian population. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-10-07 Khaled Al Oweidat,Ahmad A Toubasi,Asma S Albtoosh,Eyad Al-Mefleh,Manar M Hasuneh,Ahmed A Abdulelah,Rima A Sinan
BACKGROUND Obstructive sleep apnea (OSA) is a common cause of sleep-disordered breathing with a large proportion of the patients exhibiting positional OSA (POSA). In this study, we aimed to evaluate the differences in the demographics, comorbidities, and polysomnographic features between POSA and non-POSA (NPOSA) in a Jordanian sample to further discern the propulsive elements for each group. METHODS
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The efficiency of high-flow nasal cannula for adult patients with coronavirus disease 19 in Jeddah, Saudi Arabia. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-10-07 Majid S Al-Thaqafy,Saleh Alzahrani,Abdulwahab Alghamdi,Saleh Alselemi,Khalid Alshebani,Bussma Ahmed Bugis,Alaa Bugis,Ali S Al-Shareef
CONTEXT Early use of a high-flow nasal cannula (HFNC) provides positive outcomes for preventing the risk of intubation. However, the efficiency and usage of HFNC in the case of coronavirus disease 2019 (COVID-19) among adult patients with multiple risk factors remain debatable and require more investigation. AIMS The aim of this study was to determine the efficiency of HFNC in preventing the possible
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Lung cancer screening in the gulf: Rationale and recommendations. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-10-07 Sami M Bennji,B Jayakrishnan,Adil H Al-Kindi,Issa Al-Jahdhami,Zamzam Al-Hashami
Lung cancer is the leading cause of cancer-related death worldwide among both men and women. Although advances in therapy have been made, the 5-year survival rates for lung cancer remain poor, ranging from 10% to 20%. One of the main reasons is late presentation, as only 25% of patients are amenable to cure at the time of presentation. Therefore, the emphasis on lung cancer screening (LCS) is growing
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When single-inhaler triple therapy is a preferred option in asthma management? Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-10-07 Mohamed S Al-Moamary,Riyad Al-Lehebi,Majdy M Idrees,Mohammed O Zeitouni
Asthma control is the main goal of management. Unfortunately, most asthma patients with moderate-severe asthma remain uncontrolled despite receiving standard treatment of inhaled corticosteroids (ICS) with long-acting β2 agonists (LABA). The addition of long-acting antimuscarinic agents (LAMA) has been shown to improve different aspects of asthma control, including symptoms, lung functions, and probably
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Coinfection of pulmonary tuberculosis with other lower respiratory tract infections: A retrospective cross-sectional study. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-08-26 Marwh G Aldriwesh,Raghad A Alaqeel,Aisha M Mashraqi,Mutaib M Mashraqi,Bayan A Albdah,Azzah S Alharbi
BACKGROUND Little attention has been given to the development of lower respiratory tract infections (LRTIs) in patients with pulmonary tuberculosis (PTB) during their anti-tuberculosis (anti-TB) treatment and how that might affect patients' health status. Here, the prevalence and etiologies of other LRTIs in a cohort of PTB patients were determined, and the clinical features and outcomes were described
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Application of three-dimensional reconstruction technology combined with three-dimensional printing in the treatment of pectus excavatum. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-07-09 Yibo Shan,Guiping Yu,Yi Lu,Hao Kong,Xuewei Jiang,Zhiming Shen,Fei Sun,Hongcan Shi
OBJECTIVES To explore the clinical value of three-dimensional (3D) reconstruction technology combined with 3D printing in the treatment of pectus excavatum (PE). METHODS The clinical data of 10 patients with PE in our department from June 2018 to December 2020 were analyzed retrospectively. All patients underwent thin-layer computed tomography examination before the operation, and then 3D reconstruction
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The optimal oral body temperature cutoff and other factors predictive of sepsis diagnosis in elderly patients. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-07-09 Majid Alsalamah,Bashaer Alrehaili,Amal Almoamary,Abdulrahman Al-Juad,Mutasim Badri,Ashraf El-Metwally
INTRODUCTION The aim of this study was to identify the optimal oral temperature cut-off value and other factors predictive of sepsis in elderly patients presenting to emergency department. METHODS A hospital-based retrospective study was performed on all elderly patients who presented to the Adult Emergency Department at King Abdulaziz Medical City in Riyadh (January to December 31, 2018). RESULTS
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Comparison of radial endobronchial ultrasound-guided transbronchial lung biopsy with distance measurement versus with guide sheath in diagnosing peripheral pulmonary lesions with a diameter ≥3 cm by thin bronchoscope. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-07-09 Shuhong Guan,Jun Zhou,Qiudi Zhang,Qianqian Xu,Xiong Xu,Sujuan Zhang
OBJECTIVE This study aims to explore the diagnostic values of radial endobronchial ultrasound-guided transbronchial lung biopsy with distance (rEBUS-D-TBLB) measurement and with guide sheath (rEBUS-GS-TBLB) for peripheral pulmonary lesions (PPLs) with a diameter ≥3 cm by thin bronchoscope. PATIENTS AND METHODS Six hundred and three patients with PPL (diameter ≥3 cm) were enrolled in this study. The
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Continuous positive airway pressure therapy suppresses inflammatory cytokines and improves glucocorticoid responsiveness in patients with obstructive sleep apnea and asthma: A case-control study. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-07-09 Bassam Mahboub,Zelal Kharaba,Rakhee K Ramakrishnan,Narjes Saheb Sharif Askari,Laila Ibraheem Salameh,Hassan Saber Alhariri,Mayank G Vats,Wafa Taleb Erabia,Esra'a Mohammad Alshawamreh,Yassen Alfoteih,Andrea K Mogas,Rabih Halwani,Qutayba Hamid
CONTEXT Asthma and obstructive sleep apnea (OSA) are prevalent respiratory disorders that frequently coexist. Continuous positive airway pressure (CPAP) therapy is the standard treatment for OSA. However, its effects on systemic inflammation and glucocorticoid responsiveness in OSA patients with asthma are largely unknown. AIMS To examine the potential role of CPAP therapy in reducing systemic inflammation
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A pilot study of intraoperative intercostal nerve block during uniportal thoracoscopic wedge resection of the lung. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-07-09 Do Kyun Kang,Min Kyun Kang
BACKGROUND AND AIMS Uniportal thoracoscopic surgery has been reported to result in alleviating the postoperative pain when compared with traditional video-assisted thoracoscopic surgery (VATS). However, postoperative pain is still the main concerns associated with thoracic surgeries. The objective of this study is to evaluate the postoperative pain of patients undergoing uniportal VATS, especially
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Fibrinolysis versus thoracoscopy: Comparison of results in empyema management in the child. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-07-09 Maria Rosa Ibarra Rodríguez,Jose Ignacio Garrido Pérez,Fernando Vázquez Rueda,Francisco Javier Murcia Pascual,Sandra Rocio Wiesner Torres,Rosa Maria Paredes Esteban
OBJECTIVE The objective of this study is to compare the outcome of treatment with drainage and urokinase (UK) versus thoracoscopy (TS) in pleural empyema secondary to complicated pneumonia. METHODS This was a retrospective study of patients with complicated parapneumonic effusions between 2008 and 2019 treated with UK or TS. Epidemiological and evolutionary data compared days of fever, antibiotic,
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Obstructive sleep apnea in patients with severe asthma: Prevalence and association between severity and asthma control. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-04-19 Fatema Al-Lawati,Saif M Al-Mubaihsi,B Jayakrishnan,Sayed Rizvi,Mohammed A Al-Abri
INTRODUCTION Asthma and obstructive sleep apnea (OSA) are common respiratory disorders that can coexist and cause sleep disturbances. The strength of this association and the impact of OSA on asthma severity and control remain unclear. The study aims to estimate the prevalence of OSA in patients with severe asthma in Oman and to examine whether the severity of OSA contributed to the level of asthma
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Pathophysiology and rehabilitation management of exercise intolerance in COVID-19 patients. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-04-19 Arnengsih Nazir,Indra Putera Hasri
OBJECTIVE This review aimed to explore the pathophysiology and rehabilitation management of exercise intolerance in COVID-19 patients. METHODS We reviewed articles published in 2019-2021 using PubMed, Google Scholar, and CINAHL databases as an electronic database. Data obtained were pathophysiology and rehabilitation management of exercise intolerance in COVID-19 survivors. Types of the article were
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Challenges and recommendations for the management of asthma in the Middle East and Africa. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-04-19 Mohamed Omar Zeitouni,Mohamed Saad Al-Moamary,Marie Louise Coussa,Moussa Riachy,Bassam Mahboub,Fatma AlHuraish,Mohamed Helmy Zidan,Mohamed Mostafa Metwally,Kurtuluş Aksu,Erdinç Yavuz,Ismail Sikander Kalla,Jeremiah Chakaya,Snouber Abdelmadjid,Habib Ghedira
Clinical presentation of asthma is variable, and its diagnosis can be a major challenge in routine health-care practice, especially in low-and-middle-income countries. The aim of asthma management is to achieve optimal asthma control and to reduce the risk of asthma exacerbations and mortality. In the Middle East and in Africa (MEA), several patient- and physician-related factors lead to misdiagnosis
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Difficulties in the treatment of an infant survivor with inherited surfactant protein-B deficiency in Tunisia. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-04-19 Samia Hamouda,Ines Trabelsi,Alix de Becdelièvre,Khadija Boussetta
A female-term neonate showed a severe respiratory distress syndrome (RDS) at hour 3 of life requiring her transfer to intensive care. She was intubated and started on assist-control mechanical ventilation associated with inhaled nitric oxide then high-frequency oscillation ventilation at day 12. Chest X-ray was gradually deteriorating. Chest computed tomography (CT) scan revealed diffuse interstitial
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Evaluation of risk stratification and adherence to venous thromboembolism prophylaxis among hospitalized obstetric women: Retrospective case file review at East Jeddah Hospital during 2018-2019. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-04-19 Ghadeer Mattar,Nada Al Sahafi,Lujain Al Hazmi,Nadia Al Hazmi,Hanaa Elsayed Abozeid,Intessar Sultan
BACKGROUND Venous thromboembolism (VTE) is associated with substantial mortality as well as morbidity and is largely preventable among hospitalized obstetric women. However, thromboprophylaxis is underutilized in most hospitalized patients. OBJECTIVES To evaluate VTE risk and adherence to local thromboprophylaxis protocol among hospitalized pre- and postnatal women. METHODS This retrospective study
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The effectiveness of POST-DISCHARGE telerehabilitation practices in COVID-19 patients: Tele-COVID study-randomized controlled trial. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-04-19 Esra Pehlivan,İsmail Palalı,Sibel Gayretli Atan,Demet Turan,Halit Çınarka,Erdoğan Çetinkaya
AIMS We aimed to investigate the effectiveness of a telerehabilitation exercise program performed without requiring any special equipment on the physical condition of COVID-19 subjects. SETTINGS AND DESIGN This was a randomized controlled study. METHODS This study included subjects with a history of hospitalization with a diagnosis of COVID-19 and discharged within 4 weeks. The subjects were divided
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The association of timing of pharmacological prophylaxis and venous thromboembolism in patients with moderate-to-severe traumatic brain injury: A retrospective cohort study. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-04-19 Hasan M Al-Dorzi,Ghadah Al-Yami,Fatima Al-Daker,Muhannad Q Alqirnas,Moustafa S Alhamadh,Raymond Khan
OBJECTIVES Patients with traumatic brain injury (TBI) have an increased risk for venous thromboembolism (VTE). The current guidelines recommend pharmacologic prophylaxis, but its timing remains unclear. METHODS In this retrospective cohort study, patients with moderate-to-severe TBI admitted to a tertiary care intensive care unit between 2016 and 2019 were categorized into two groups according to the
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COVID-19 reinfection: A multicenter retrospective study in Saudi Arabia. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-04-19 Naila A Shaheen,Rakan Sambas,Maha Alenezi,Naif Khalaf Alharbi,Omar Aldibasi,Mohammad Bosaeed
INTRODUCTION There are limited direct data on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) long-term immune responses and reinfection. This study aimed to evaluate the rate, risk factors, and severity of COVID-19 reinfection. METHODS This retrospective cohort study included five hospitals across Saudi Arabia. All subjects who were presented or admitted with positive SARS-CoV-2 real-time
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Diagnostic value of bronchoscopy in sputum-negative pulmonary tuberculosis patients and its correlation with clinicoradiological features. Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-04-19 Sadia Imtiaz,Enas Mansour Batubara
CONTEXT Tuberculosis (TB) remains endemic in Saudi Arabia. Little local data have been reported on bronchoscopic evaluation of sputum-negative pulmonary TB patients, which poses a significant diagnostic and therapeutic challenge. AIMS To determine the diagnostic value of bronchoscopy and bronchoalveolar lavage (BAL) and its correlation with clinical and radiological features in sputum-negative, culture-confirmed
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COVID-19 vaccine-induced immune thrombotic thrombocytopenia: A review Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-01-01 Malay Sarkar, Irappa V Madabhavi, Pham Nguyen Quy, Manjunath B Govindagoudar
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus responsible for the pandemic coronavirus disease 19 (COVID-19). It has significant impact on human health and public safety along with negative social and economic consequences. Vaccination against SARS-CoV-2 is likely the most effective approach to sustainably control the global COVID-19
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Effects of transcutaneous electrical diaphragmatic stimulation on respiratory function in patients with prolonged mechanical ventilation Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-01-01 Yi-Fei Hsin, Shu-Hsin Chen, Teng-Jen Yu, Chung-Chi Huang, Yen-Huey Chen
PURPOSE: Muscle atrophy and diaphragm dysfunction are common with prolonged mechanical ventilation (PMV). Electrical stimulation on peripheral muscles has been shown to be beneficial in the improvement of muscle function. This study examined the effects of transcutaneous electrical diaphragmatic stimulation (TEDS) on respiratory muscle strength and weaning outcomes in patients with PMV. METHODS: Participants
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Sleep quality and mental health in coronavirus disease 2019 patients and general population during the pandemic Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-01-01 Ranya Alshumrani, Sultan Qanash, Ahmad Aldobyany, Faris Alhejaili, Ibrahim AlQassas, Mohammed Shabrawishi, Omar Alnashiwaty, Mohannad Badghaish, Mohammad Adnan, Ahmed Bin Afeef, Dhafer Alghamdi, Salman Aljehani, Anas Alsurahi, Abdulaziz Faruqui, Ayman Krayem, Md Dilshad Manzar, Siraj Wali
OBJECTIVE: Sleep problems during the coronavirus disease 2019 (COVID-19) pandemic commonly affected general populations. Data on the effect of the COVID-19 pandemic on sleep quality in Saudi Arabia are scarce. Thus, the aim of our study was to evaluate sleep quality and assess the psychological burden of the pandemic in COVID-19 patients and the general population. METHODS: This was a multicenter,
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Long-term COVID-19 effects on pulmonary function, exercise capacity, and health status Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-01-01 Doaa M Magdy, Ahmed Metwally, Doaa Abdel Tawab, Shimaa Abaas Hassan, Marwa Makboul, Shimaa Farghaly
BACKGROUND: The long-term effects of respiratory function and related physiological characteristics of coronavirus disease 2019 (COVID-19) survivors have not yet been studied in depth. OBJECTIVE: To examine pulmonary function, exercise capacity, and health-related quality of life among COVID-19 survivors. METHODS: Eighty-five survivors with confirmed COVID-19 were evaluated at the end of 3 and 6 months
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Humidification during mechanical ventilation to prevent endotracheal tube occlusion in critically ill patients: A case control study Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-01-01 Hasan M Al Dorzi, Alaaeldien G Ghanem, Mohamed Moneer Hegazy, Amal AlMatrood, John Alchin, Mohammed Mutairi, Ahmad Aqeil, Yaseen M Arabi
BACKGROUND: Endotracheal tube (ETT) occlusion is a potentially life-threatening event. This study describes a quality improvement project to prevent ETT occlusion in critically ill patients. METHODS: After a cluster of clinically significant ETT occlusion incidents at a tertiary-care intensive care unit (ICU), the root cause analysis suggested that the universal use of heat moisture exchangers (HMEs)
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Surgical treatment outcomes of pulmonary inflammatory myofibroblastic tumors Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-01-01 Ömer Faruk Demir, Omer Onal
BACKGROUND: Pulmonary inflammatory myofibroblastic tumor (PIMT) is an extremely rare disease. The aim of this study was to share the surgical outcomes of these tumors. METHODS: Patients who were operated for pulmonary myofibroblastic tumors between January 2005 and January 2021 were determined by retrospectively scanning patient files. Patients' demographic characteristics, tumor location, surgical
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Surgical and mediastinal emphysema in critically ill COVID-19 patients: A multicentric experience Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-01-01 Yasser Aljehani, Auday A Alkhunaizi, Sharifah A Othman, Hassan Abdullah Alqumber, Yousif Almubarak, Tariq Al-Musawi, Mohammed Ibrahim Al Bazroun, Khatoon Alshaikhmohamed
INTRODUCTION: Coronavirus illness 2019, commonly referred to as COVID-19, is a highly infectious disease brought on by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 was declared a universal pandemic in March 2020 by the World Health Organization and is a severe health issue with unprecedented morbidity and mortality rates. Both surgical and mediastinal emphysema have been seen
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Characteristics and outcome of tertiary care critically ill COVID-19 patients with multiple comorbidities admitted to the intensive care unit Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-01-01 Imran Khalid, Abeer N Alshukairi, Tabindeh Jabeen Khalid, Maryam Imran, Manahil Imran, Muhammad Ali Akhtar, Ghassan Y Wali
PURPOSE: We conducted this study to evaluate the characteristics and outcomes exclusively in high-risk coronavirus disease 2019 (COVID-19) tertiary care patients with multiple comorbidities, as very few have reported outcomes in this specific cohort. METHODS: All patients, with two or more risk factors for COVID-19 and Charlson Comorbidity Index (CCI) of >2, who were admitted to intensive care unit
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A COVID-19 family cluster with retinitis pigmentosa and hypogammaglobulinemia Ann. Thorac. Med. (IF 2.3) Pub Date : 2022-01-01 Abeer N Alshukairi, Yasser A Aldabbagh, Najla M Sayes, Manal M Al Gethamy, Mohammed G Alghamdi, Zuhair A Rahbeeni, Ashraf Dada
Hypogammaglobulinemia is a heterogeneous group of innate and acquired antibody deficiency with variable disease severity, recurrent pneumonia, and bronchiectasis. The outcome of COVID in patients with hypogammaglobulinemia is variable depending on age, comorbidities, type of immunodeficiency, and use of immunoglobulins. We report the favorable outcome of two family members diagnosed with DNAJC17-related
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Pulmonary rehabilitation for COPD: A narrative review and call for further implementation in Saudi Arabia Ann. Thorac. Med. (IF 2.3) Pub Date : 2021-10-01 Abdulelah M Aldhahir, Saeed M Alghamdi, Jaber S Alqahtani, Khaled A Alqahtani, Ahmed M Al Rajah, Bedor S Alkhathlan, Sally J Singh, Swapna Mandal, John R Hurst
Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable condition, in which outcomes can be improved with careful management. Pulmonary rehabilitation (PR) comprises exercise and education, delivered by multidisciplinary teams. PR is a cost-effective management strategy in COPD patients which improves exercise performance, reduces dyspnea, reduces the risk of exacerbation
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Bilevel positive airway pressure ventilation for non-COPD acute hypercapnic respiratory failure patients: A systematic review and meta-analysis Ann. Thorac. Med. (IF 2.3) Pub Date : 2021-10-01 Bandar M Faqihi, Samuel P Trethewey, Julien Morlet, Dhruv Parekh, Alice M Turner
The effectiveness of bi-level positive airway pressure (BiPAP) in patients with acute hypercapnic respiratory failure (AHRF) due to etiologies other than chronic obstructive pulmonary disease (COPD) is unclear. To systematically review the evidence regarding the effectiveness of BiPAP in non-COPD patients with AHRF. The Cochrane Library, MEDLINE, EMBASE, and CINAHL Plus were searched according to prespecified
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Drug susceptibility profiling of pulmonary Mycobacterium kansasii and its correlation with treatment outcome Ann. Thorac. Med. (IF 2.3) Pub Date : 2021-10-01 Priya Rajendran, Chandrasekaran Padmapriyadarsini, Vaishnavee Vijayaraghavan, Tamizhselvan Manoharan, Lakshana Malla Lokanathan, Parveen Banu Kadhar, Lavanya Jayabal, Gomathy Sivaramakrishnan
OBJECTIVES: With the introduction of newer molecular diagnostic tools to identify Mycobacterium tuberculosis, an increasing number of nontuberculous mycobacterium (NTM) is being identified. However, the drug resistance pattern of the NTM species identified is less explored. The objective of this study is to study the drug resistance patterns of Mycobacterium kansasii species isolated in a tuberculosis-endemic
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Putative associations between inflammatory biomarkers, obesity, and obstructive sleep apnea Ann. Thorac. Med. (IF 2.3) Pub Date : 2021-10-01 Siraj Omar Wali, Md Dilshad Manzar, Mohammed M Abdelaziz, Ranya Alshomrani, Faris Alhejaili, Jamil Al-Mughales, Wail Alamoudi, David Gozal
BACKGROUND: Previous studies have reported increased levels of inflammatory mediators in patients with obstructive sleep apnea (OSA), but their relation with the severity of OSA is controversial. OBJECTIVE: To address potential relationships between OSA-related inflammatory markers, namely, C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), and fibrinogen, with different
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Efficacy of acetazolamide for the prophylaxis of acute mountain sickness: A systematic review, meta-analysis, and trial sequential analysis of randomized clinical trials Ann. Thorac. Med. (IF 2.3) Pub Date : 2021-10-01 Daiquan Gao, Yuan Wang, Rujiang Zhang, Yunzhou Zhang
BACKGROUND: Acute mountain sickness (AMS) is a benign and self-limiting syndrome, but can progress to life-threatening conditions if leave untreated. This study aimed to assess the efficacy of acetazolamide for the prophylaxis of AMS, and disclose factors that affect the treatment effect of acetazolamide. METHODS: Randomized controlled trials comparing the use of acetazolamide versus placebo for the