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Deciphering cellular and molecular mechanism of MUC13 mucin involved in cancer cell plasticity and drug resistance Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-03-18 Shabnam Malik, Mohammed Sikander, Mohd Wahid, Anupam Dhasmana, Maryam Sarwat, Sheema Khan, Everardo Cobos, Murali M. Yallapu, Meena Jaggi, Subhash C. Chauhan
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The fibro-adipogenic progenitor APOD+DCN+LUM+ cell population in aggressive carcinomas Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-03-11 Lingyi Cai, Mikhail G. Kolonin, Dimitris Anastassiou
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TFCP2 as a therapeutic nexus: unveiling molecular signatures in cancer Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-03-07 Neha Kaushik, Apurva Jaiswal, Pradeep Bhartiya, Eun Ha Choi, Nagendra Kumar Kaushik
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Lipid metabolism and its implications in tumor cell plasticity and drug resistance: what we learned thus far? Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-03-05 Ravichandran Vishwa, Bandari BharathwajChetty, Sosmitha Girisa, Babu Santha Aswani, Mohammed S. Alqahtani, Mohamed Abbas, Mangala Hegde, Ajaikumar B. Kunnumakkara
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Survival mechanisms of circulating tumor cells and their implications for cancer treatment Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-03-04 Shuang Zhou, Huanji Xu, Yichun Duan, Qiulin Tang, Huixi Huang, Feng Bi
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Epidemiology of nasopharyngeal carcinoma: current insights and future outlook Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-03-02 Zhi Yi Su, Pui Yan Siak, Yu Yu Lwin, Shiau-Chuen Cheah
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Comprehensive assessment of TECENTRIQ® and OPDIVO®: analyzing immunotherapy indications withdrawn in triple-negative breast cancer and hepatocellular carcinoma Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-02-27 Ghazaal Roozitalab, Behnaz Abedi, Saber Imani, Reyhaneh Farghadani, Parham Jabbarzadeh Kaboli
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Molecular panorama of therapy resistance in prostate cancer: a pre-clinical and bioinformatics analysis for clinical translation Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-02-19 Milad Ashrafizadeh, Wei Zhang, Yu Tian, Gautam Sethi, Xianbin Zhang, Aiming Qiu
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Cancer cell plasticity: from cellular, molecular, and genetic mechanisms to tumor heterogeneity and drug resistance Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-02-08 Gh Rasool Bhat, Itty Sethi, Hana Q. Sadida, Bilal Rah, Rashid Mir, Naseh Algehainy, Ibrahim Altedlawi Albalawi, Tariq Masoodi, Gowtham Kumar Subbaraj, Farrukh Jamal, Mayank Singh, Rakesh Kumar, Muzafar A. Macha, Shahab Uddin, Ammira S. Al-Shabeeb Akil, Mohammad Haris, Ajaz A. Bhat
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Clusterin: a marker and mediator of chemoresistance in colorectal cancer Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-02-06 Sara Hlavca, Wing Hei Chan, Rebekah M. Engel, Helen E. Abud
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Therapeutic importance and diagnostic function of circRNAs in urological cancers: from metastasis to drug resistance Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-01-22 Zhibin Zhang, Zhixu Gao, Huimin Fang, Yutang Zhao, Rong Xing
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The impact of tumor microenvironment: unraveling the role of physical cues in breast cancer progression Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-01-19 Ayuba Akinpelu, Tosin Akinsipe, L. Adriana Avila, Robert D. Arnold, Panagiotis Mistriotis
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Epigenetic reprogramming of T cells: unlocking new avenues for cancer immunotherapy Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-01-18 Vipin Singh, Sandhik Nandi, Aritra Ghosh, Santanu Adhikary, Shravanti Mukherjee, Siddhartha Roy, Chandrima Das
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The emerging roles of histone demethylases in cancers Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-01-16 Dali Tong, Ying Tang, Peng Zhong
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Harnessing function of EMT in cancer drug resistance: a metastasis regulator determines chemotherapy response Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-01-16
Abstract Epithelial-mesenchymal transition (EMT) is a complicated molecular process that governs cellular shape and function changes throughout tissue development and embryogenesis. In addition, EMT contributes to the development and spread of tumors. Expanding and degrading the surrounding microenvironment, cells undergoing EMT move away from the main location. On the basis of the expression of fibroblast-specific
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UCP2 and pancreatic cancer: conscious uncoupling for therapeutic effect Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-01-09 Emily G. Caggiano, Cullen M. Taniguchi
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Deciphering cellular plasticity in pancreatic cancer for effective treatments Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-01-09
Abstract Cellular plasticity and therapy resistance are critical features of pancreatic cancer, a highly aggressive and fatal disease. The pancreas, a vital organ that produces digestive enzymes and hormones, is often affected by two main types of cancer: the pre-dominant ductal adenocarcinoma and the less common neuroendocrine tumors. These cancers are difficult to treat due to their complex biology
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PRUNE1 and NME/NDPK family proteins influence energy metabolism and signaling in cancer metastases Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-01-05 Veronica Ferrucci, Santosh Lomada, Thomas Wieland, Massimo Zollo
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Glucocorticoid receptor: a harmonizer of cellular plasticity in breast cancer—directs the road towards therapy resistance, metastatic progression and recurrence Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-01-03 Debanjan Thakur, Debomita Sengupta, Elizabeth Mahapatra, Salini Das, Ruma Sarkar, Sutapa Mukherjee
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Targeting the key players of phenotypic plasticity in cancer cells by phytochemicals Cancer Metastasis Rev. (IF 9.2) Pub Date : 2024-01-03 Sajad Fakhri, Seyed Zachariah Moradi, Fatemeh Abbaszadeh, Farahnaz Faraji, Roshanak Amirian, Dona Sinha, Emily G. McMahon, Anupam Bishayee
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Colorectal cancer: a comprehensive review of carcinogenesis, diagnosis, and novel strategies for classified treatments Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-12-19 Roya Abedizadeh, Fateme Majidi, Hamid Reza Khorasani, Hassan Abedi, Davood Sabour
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HOXA9 transcription factor is a double-edged sword: from development to cancer progression Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-12-08 U Sangeetha Shenoy, Divya Adiga, Faisal Alhedyan, Shama Prasada Kabekkodu, Raghu Radhakrishnan
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Regulation and targeting of SREBP-1 in hepatocellular carcinoma Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-12-01 Fengting Su, Andreas Koeberle
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Targeting vimentin: a multifaceted approach to combatting cancer metastasis and drug resistance Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-11-28 Aliye Tabatabaee, Behjat Nafari, Armin Farhang, Amirali Hariri, Arezoo Khosravi, Ali Zarrabi, Mina Mirian
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Metastasis suppressor genes and their role in the tumor microenvironment Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-11-20 Cristina Megino-Luque, Jose Javier Bravo-Cordero
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From modulation of cellular plasticity to potentiation of therapeutic resistance: new and emerging roles of MYB transcription factors in human malignancies Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-11-10 Shashi Anand, Kunwar Somesh Vikramdeo, Sarabjeet Kour Sudan, Amod Sharma, Srijan Acharya, Mohammad Aslam Khan, Seema Singh, Ajay Pratap Singh
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Tumor ablation induced anti-tumor immunity: destruction of the tumor in situ with the aim to evoke a robust anti-tumor immune response. Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-11-11 Yona Keisari,Itzhak Kelson
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Clonal tracking in cancer and metastasis Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-11-01 Syed Mohammed Musheer Aalam, Long Viet Nguyen, Megan L. Ritting, Nagarajan Kannan
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Targeting microRNAs as a promising anti-cancer therapeutic strategy against traffic-related air pollution-mediated lung cancer Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-11-01 Hamed Kazemi Shariat Panahi, Mona Dehhaghi, Gilles J. Guillemin, Wanxi Peng, Mortaza Aghbashlo, Meisam Tabatabaei
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Prospects of earthworm coelomic fluid as a potential therapeutic agent to treat cancer Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-11-01 Shafiul Haque, Arif Hussain, Atiah H. Almalki, Mohammed F. Aldawsari, Basant Lal, Ashutosh Kumar Rai, Manish Srivastava, Marta Fiołka
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Epigenetic regulation of breast cancer metastasis Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-10-19 Chitra Thakur, Yiran Qiu, Aashna Pawar, Fei Chen
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Tissue-derived extracellular vesicles in cancer progression: mechanisms, roles, and potential applications Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-10-18 Ziyang Ye, Wenjie Chen, Genpeng Li, Jing Huang, Jianyong Lei
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Sam68 is a druggable vulnerability point in cancer stem cells Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-10-04 Amanda Mendes da Silva, Veronika Yevdokimova, Yannick D. Benoit
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Cancer cell plasticity, stem cell factors, and therapy resistance: how are they linked? Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-10-05 Homa Fatma, Hifzur R. Siddique
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Cell plasticity modulation by flavonoids in resistant breast carcinoma targeting the nuclear factor kappa B signaling Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-10-04 Peter Kubatka, Lenka Koklesova, Alena Mazurakova, Aranka Brockmueller, Dietrich Büsselberg, Martin Kello, Mehdi Shakibaei
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Modulation of hypoxia-inducible factor-1 signaling pathways in cancer angiogenesis, invasion, and metastasis by natural compounds: a comprehensive and critical review Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-10-04 Sajad Fakhri, Seyed Zachariah Moradi, Farahnaz Faraji, Leila Kooshki, Kassidy Webber, Anupam Bishayee
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Epithelial-to-mesenchymal transition in cancer progression: unraveling the immunosuppressive module driving therapy resistance Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-09-30 Deepti Singh, Hifzur R. Siddique
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B7-H3 at the crossroads between tumor plasticity and colorectal cancer progression: a potential target for therapeutic intervention Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-09-28 Elizabeth Varghese, Samson Mathews Samuel, Aranka Brockmueller, Mehdi Shakibaei, Peter Kubatka, Dietrich Büsselberg
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Metastasis suppressor genes in clinical practice: are they druggable? Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-09-25 Irwin H. Gelman
Since the identification of NM23 (now called NME1) as the first metastasis suppressor gene (MSG), a small number of other gene products and non-coding RNAs have been identified that suppress specific parameters of the metastatic cascade, yet which have little or no ability to regulate primary tumor initiation or maintenance. MSG can regulate various pathways or cell biological functions such as those
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Next-generation immune checkpoint inhibitors as promising functional molecules in cancer therapeutics Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-09-20 Anupam Dhasmana, Swati Dhasmana, Shafiul Haque, Everardo Cobos, Murali M. Yallapu, Subhash C. Chauhan
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The emerging role of the gut microbiome in cancer cell plasticity and therapeutic resistance Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-09-14 Priya Mondal, Syed Musthapa Meeran
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Epigenetic control of pancreatic cancer metastasis Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-09-02 Lukas Krauß, Carolin Schneider, Elisabeth Hessmann, Dieter Saur, Günter Schneider
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A perspective on the metastasis suppressor field Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-08-15 Imran Khan, Patricia S. Steeg
Metastasis is the leading cause of cancer patient mortality. Metastasis suppressors are genes that, upon reexpression in metastatic tumor cells to levels observed in their nonmetastatic counterparts, significantly reduce metastasis without affecting the growth of the primary tumor. Analysis of > 30 metastasis suppressors revealed complex mechanisms of action that include multiple signaling pathways
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New progress of tuberculosis scar carcinoma Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-08-16 Wenwen Sun, Yujin Liu, Lishu Zhao, Hao Wang, Li Ye, Xinyue Liu, Kandi Xu, Yu Chen, Lin Fan
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The strict regulation of HIF-1α by non-coding RNAs: new insight towards proliferation, metastasis, and therapeutic resistance strategies Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-08-08 Sabrean Farhan Jawad, Farag M. A. Altalbawy, Radhwan M. Hussein, Ali Abdulhussain Fadhil, Mohammed Abed Jawad, Rahman S. Zabibah, Tasneem Younus Taraki, Chakrabhavi Dhananjaya Mohan, Kanchugarakoppal S. Rangappa
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Is cancer an intelligent species? Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-08-04 Chiara Nicolazzo, Federica Francescangeli, Valentina Magri, Alessandro Giuliani, Ann Zeuner, Paola Gazzaniga
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Metastasis suppressors: a paradigm shift in cancer biology. Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-08-03 Danny R Welch
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Resveratrol as sensitizer in colorectal cancer plasticity Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-07-29 Aranka Brockmueller, Anjana Sajeev, Lenka Koklesova, Samson Mathews Samuel, Peter Kubatka, Dietrich Büsselberg, Ajaikumar B. Kunnumakkara, Mehdi Shakibaei
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Current advances in nanoformulations of therapeutic agents targeting tumor microenvironment to overcome drug resistance Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-07-28 Sajad Fakhri, Seyed Zachariah Moradi, Farahnaz Faraji, Tara Farhadi, Osman Hesami, Amin Iranpanah, Kassidy Webber, Anupam Bishayee
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Targeting miRNA and using miRNA as potential therapeutic options to bypass resistance in pancreatic ductal adenocarcinoma Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-07-25 Mahrou Vahabi, Bilal Dehni, Inés Antomás, Elisa Giovannetti, Godefridus J. Peters
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Helicobacter pylori–activated fibroblasts as a silent partner in gastric cancer development Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-07-17 Gracjana Krzysiek-Maczka, Tomasz Brzozowski, Agata Ptak-Belowska
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Molecular profile of metastasis, cell plasticity and EMT in pancreatic cancer: a pre-clinical connection to aggressiveness and drug resistance Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-07-15 Zhenli Guo, Milad Ashrafizadeh, Wei Zhang, Rongjun Zou, Gautam Sethi, Xianbin Zhang
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How circulating tumor cluster biology contributes to the metastatic cascade: from invasion to dissemination and dormancy Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-07-13 Mostafa M Nasr, Conor C Lynch
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Short-chain fatty acids in cancer pathogenesis Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-07-11 Mark A. Feitelson, Alla Arzumanyan, Arvin Medhat, Ira Spector
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Potent molecular-targeted therapies for gastro-entero-pancreatic neuroendocrine carcinoma Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-07-08 Akira Ooki, Hiroki Osumi, Koshiro Fukuda, Kensei Yamaguchi
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Carcinoma of unknown primary (CUP): an update for histopathologists Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-07-03 Katie Beauchamp, Bruce Moran, Timothy O’Brien, Donal Brennan, John Crown, Kieran Sheahan, Maura Bríd Cotter
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Cancer metastasis under the magnifying glass of epigenetics and epitranscriptomics Cancer Metastasis Rev. (IF 9.2) Pub Date : 2023-06-28 Maxime Janin, Veronica Davalos, Manel Esteller