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Three‐dimensional computed tomography‐based resection process map for robot‐assisted partial nephrectomy: propensity score matching of a single‐center retrospective study J. Surg. Oncol. (IF 2.5) Pub Date : 2024-03-12 Atsushi Okada, Kazuya Ohashi, Hiroya Hashimoto, Yuya Ota, Teruaki Sugino, Rei Unno, Shoichiro Iwatsuki, Toshiki Etani, Kazumi Taguchi, Taku Naiki, Satoshi Kurokawa, Shuzo Hamamoto, Ryosuke Ando, Akihiro Nakane, Noriyasu Kawai, Keiichi Tozawa, Takahiro Yasui
Background and ObjectivesWe aimed to examine the effect of preoperative three‐dimensional (3D) computed tomography (CT)‐based resection process map (RPM) imaging on the outcomes of robot‐assisted partial nephrectomy (RAPN).MethodsWe retrospectively analyzed 177 patients (RPM group, n = 92; non‐RPM group, n = 85) who underwent this surgery between November 2012 and April 2022. Patient‐specific contrast‐enhanced
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Sporadic deficient mismatch repair in colorectal cancer increases the risk for non‐colorectal malignancy: A European multicenter cohort study J. Surg. Oncol. (IF 2.5) Pub Date : 2024-03-12 Ioannis Gkekas, Novotny Jan, Tuomas Kaprio, Ines Beilmann‐Lehtonen, Pavel Fabian, Björn Tavelin, Camilla Böckelman, Sofia Edin, Karin Strigård, Tomas Svoboda, Jaana Hagström, Lucie Barsova, Tomas Jirasek, Caj Haglund, Richard Palmqvist, Ulf Gunnarsson
Background and ObjectivesDisparities between tumors arising via different sporadic carcinogenetic pathways have not been studied systematically. This retrospective multicenter cohort study evaluated the differences in the risk for non‐colorectal malignancy between sporadic colorectal cancer (CRC) patients from different DNA mismatch repair status.MethodsA retrospective European multicenter cohort study
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A comparison of three different microwave systems for laparoscopic liver tumor ablation J. Surg. Oncol. (IF 2.5) Pub Date : 2024-03-12 Eren Berber, Ali Gunduz Sarioglu, Ege Akgun
BackgroundOur aim was to perform a comparison of three current microwave ablation (MWA) systems widely used for laparoscopic liver ablations in terms of ablation kinetics and geometry of ablation zones.MethodsThis was a retrospective, institutional review board‐approved study comparing Emprint, Emprint HP, and NeuWave systems for laparoscopic liver ablation. Analyses were performed via Mann−Whitney
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Identifying low cancer‐specific mortality risk lymph node‐positive radical prostatectomy patients J. Surg. Oncol. (IF 2.5) Pub Date : 2024-03-12 Francesco Barletta, Stefano Tappero, Simone Morra, Reha‐Baris Incesu, Cristina Cano Garcia, Mattia L. Piccinelli, Lukas Scheipner, Zhe Tian, Giorgio Gandaglia, Armando Stabile, Elio Mazzone, Carlo Terrone, Nicola Longo, Derya Tilki, Felix K. H. Chun, Ottavio de Cobelli, Sascha Ahyai, Fred Saad, Shahrokh F. Shariat, Francesco Montorsi, Alberto Briganti, Pierre I. Karakiewicz
ObjectivesTo identify low cancer‐specific mortality (CSM) risk lymph node‐positive (pN1) radical prostatectomy (RP) patients.MethodsWithin Surveillance, Epidemiology and End Results database (2010–2015) pN1 RP patients were identified. Kaplan–Meier plots and multivariable Cox‐regression (MCR) models were used. Pathological characteristics were used to identify patients at lowest CSM risk.ResultsOverall
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Reporting of core outcomes in gastric cancer surgery trials over the past 25 years (systematic review) J. Surg. Oncol. (IF 2.5) Pub Date : 2024-03-06 Anie Naqvi, Nadia Matias, Bilal Al‐Khaffaf
BackgroundGastric cancer, a leading cause of cancer‐related mortality worldwide, has seen limited improvement in survival over the past 3 decades. Surgical resection is the cornerstone of curative management but the optimal approach remains unclear. Decision‐making is hindered by inconsistent outcome reporting limiting data synthesis between trials. International consensus between healthcare professionals
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Can cell‐free DNA (cfDNA) in pleural lavage serve as a predictive and prognostic biomarker among surgically treated Stage I−III a nonsmall cell lung cancer (NSCLC)? A pilot study J. Surg. Oncol. (IF 2.5) Pub Date : 2024-03-04 Jyoutishman Saikia, Prabhat S. Malik, Sachin Kumar, Deepali Jain, Karan Madan, Sachidanand Jee Bharati, Suryanarayana Deo, Sunil Kumar
Background and ObjectivesThe role of cell‐free DNA (cfDNA) in operable nonsmall cell lung cancer (NSCLC) is unclear. This study was aimed to evaluate the feasibility for identification of cfDNA in pleural lavage fluid and its correlation with plasma in resectable NSCLCs.MethodsConsecutively resected NSCLCs were evaluated for cfDNA levels in preoperative plasma (PLS1), intraoperative pleural‐lavage
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Distinct presentation of melanoma in Black patients may inform strategies to improve outcomes J. Surg. Oncol. (IF 2.5) Pub Date : 2024-03-04 Jessica A. Steadman, Amy E. Glasgow, Nikki N. Neequaye, Elizabeth B. Habermann, Tina J. Hieken
IntroductionMelanoma guidelines stem largely from data on non‐Hispanic White (NHW) patients. We aimed to identify features of melanoma within non‐Hispanic Black (NHB) patients to inform strategies for earlier detection and treatment.MethodsFrom 2004 to 2019 Surveillance, Epidemiology, and End Results (SEER) data, we identified nonmetastatic melanoma patients with known TN category and race. Kaplan–Meier
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Sentinel lymph node biopsy for melanoma in the older population: A prospective analysis of outcomes J. Surg. Oncol. (IF 2.5) Pub Date : 2024-03-04 Murtaza Kadhum, Laura Mayr, Sophie Pope‐Jones, Jonathan Cubitt, Sarah Hemington‐Gorse
BackgroundThe use of sentinel lymph node biopsy (SLNB) in the older population, defined as those over 70 years old, has been debated since the adoption of SLNB into routine practice. Interestingly, there remains a paucity of evidence, especially regarding the rates of SLNB positivity, complications, and subsequent adjuvant therapy in those with node positivity.MethodData on patient's comorbidities
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Contemporary report of surgical outcomes after single‐stage total pancreatectomy: A 10‐year experience J. Surg. Oncol. (IF 2.5) Pub Date : 2024-02-29 Nitzan Zohar, Luke Kowal, David Moskal, Francesca Ponzini, George Sun, Ryan J. Lamm, John Williamson, Avinoam Nevler, Harish Lavu, Warren R. Maley, Charles J. Yeo, Wilbur B. Bowne
BackgroundSurgeons rarely perform elective total pancreatectomy (TP). Our study seeks to report surgical outcomes in a contemporary series of single‐stage (SS) TP patients.MethodsBetween the years 2013 to 2023 we conducted a retrospective review of 60 consecutive patients who underwent SSTP. Demographics, pathology, treatment‐related variables, and survival were recorded and analyzed.ResultsSSTP consisted
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Artificial intelligence in head and neck surgery: Potential applications and future perspectives J. Surg. Oncol. (IF 2.5) Pub Date : 2024-02-29 Bartosz Wojtera, Mateusz Szewczyk, Piotr Pieńkowski, Wojciech Golusiński
Artificial intelligence (AI) has the potential to improve the surgical treatment of patients with head and neck cancer. AI algorithms can analyse a wide range of data, including images, voice, molecular expression and raw clinical data. In the field of oncology, there are numerous AI practical applications, including diagnostics and treatment. AI can also develop predictive models to assess prognosis
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Impact of the pandemic on surgical oncology in Piedmont, Italy: A retrospective observational study J. Surg. Oncol. (IF 2.5) Pub Date : 2024-02-29 Giuseppina Lo Moro, Paolo Ragusa, Christian Previti, Alessandro Comandone, Mario Airoldi, Massimo Aglietta, Roberta Siliquini
Background and MethodsThis retrospective observational study analyzes how the COVID‐19 pandemic affected surgical oncology healthcare in a large sample from Piedmont, Northern Italy. Patients admitted for regular hospitalization were included (n = 99 651). Data from 2020 were compared to the averages from 2016 to 2019, stratified by tumor site, year, month, and admission method, using interrupted time
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Seek and ye shall find: The utility of perioperative VTE screening in high‐risk oncologic patients undergoing abdominopelvic surgery J. Surg. Oncol. (IF 2.5) Pub Date : 2024-02-29 Eric R. Pletcher, Allison Nguyen‐Thai, Tiffany Lim, Allan W. Silberman
Background and ObjectiveThe aim of this study was to evaluate the prevalence and risk factors associated with perioperative venous thromboembolism (VTE) in patients undergoing major oncologic surgery using an epidural catheter (EC) for postoperative analgesia with mechanical prophylaxis and without chemoprophylaxis.MethodsSix hundred and twenty‐six patients undergoing major oncologic surgery from 2009
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Free flap reconstruction at a rural‐based tertiary medical college hospital: Barriers and outcomes J. Surg. Oncol. (IF 2.5) Pub Date : 2024-02-28 Deepak Hongaiah, Abhay K. Kattepur, Eldo V. George, Abhishek Mahadev M., Deepika Kenkere, Aswathappa Dasappa
Background and ObjectivesIn a rural‐based setting, providing optimal treatment is often difficult owing to the limited resources and financial constraints being rampant in cancer care delivery. Oncological resections often result in large, complex defects requiring free flap reconstruction to achieve cosmetic and/or functional goals. This article focuses on our experience of starting and promoting
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Operative trends following the adoption of nonoperative management of rectal cancer J. Surg. Oncol. (IF 2.5) Pub Date : 2024-02-26 Justin Brewer, Maseray Kamara, Marianne Huebner, Elias Taxakis, Karen Grajewski, Carole Ramm, Robert K. Cleary
BackgroundDifferentiating clinical near‐complete and complete responses (cCR) after neoadjuvant therapy (NT) is challenging in rectal cancer patients. We hypothesized that magnetic resonance imaging staging limitations for low rectal cancers may increase the proportion of abdominoperineal resection (APR) with permanent colostomy for those without a cCR.MethodsSingle institution retrospective analysis
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Outcomes of rectal cancer patients who refuse surgery after incomplete clinical response to neoadjuvant therapy J. Surg. Oncol. (IF 2.5) Pub Date : 2024-02-24 Kevin P. Labadie, Kristofor A. Olson, Steven H. Sun, Philip H. G. Ituarte, Mark Hanna, Yasmin Zerhouni, Lily L. Lai, Stephen M. Sentovich, Andreas M. Kaiser, Kurt A. Melstrom
Background and ObjectivesTotal mesorectal excision (TME) remains the standard of care for patients with rectal cancer who have an incomplete response to total neoadjuvant therapy (TNT). A minority of patients will refuse curative intent resection. The aim of this study is to examine the outcomes for these patients.MethodsA retrospective cohort study of stage 1−3 rectal adenocarcinoma patients who underwent
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Points to consider regarding prophylactic total gastrectomy in germline CDH1 variant carriers J. Surg. Oncol. (IF 2.5) Pub Date : 2024-02-23 Giovanni Corso, Jeremy L. Davis, Vivian E. Strong
Pathogenic germline CDH1 mutation confers high risk for developing diffuse gastric and lobular breast cancers in asymptomatic carriers. In these individuals, the estimated gastric cancer risk at 80 years of age is up to 70% for males and 56% for females. Due to this high‐risk predisposition, prophylactic total gastrectomy is considered a unique life‐saving approach in germline CDH1 carriers, as endoscopy
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Intravenous tranexamic acid reduces complications following surgical treatment of pathologic fractures of the lower extremity J. Surg. Oncol. (IF 2.5) Pub Date : 2024-02-22 Brandon S. Gettleman, Kevin C. Liu, Mary K. Richardson, Matthew Chen, Arad Talehakimi, Nathanael D. Heckmann, Lawrence Menendez, Alexander B. Christ
Background and ObjectivesThis study aimed to evaluate the postoperative complications associated with administering intravenous (IV) tranexamic acid (TXA) in patients undergoing surgical fixation for neoplastic pathologic fractures of the lower extremities.MethodsPatients ≥18 years old who underwent surgical intervention for neoplastic pathologic lower extremity fractures from 2015 to 2021 were identified
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A guide for addressing sexual health in breast cancer patients J. Surg. Oncol. (IF 2.5) Pub Date : 2024-02-22 Minji Kim, Jeanne Carter, Audree B. Tadros, Nour Abuhdra, Jonas A. Nelson, Carrie S. Stern
PurposeSexual health concerns are common in breast cancer surgery but often overlooked. Yet, breast cancer patients want more sexual health information from their providers. We aimed to share ways for providers to address sexual health concerns with their breast cancer patients at different stages of the treatment process.MethodsExperts in breast cancer treatments, surgeries, and sexual health at Memorial
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Neuroendocrine neoplasms of the gallbladder: A single institute analysis of outcomes and prognostic factors J. Surg. Oncol. (IF 2.5) Pub Date : 2024-02-13 Kunal Nandy, Shraddha Patkar, Subhash Yadav, Vikas Ostwal, Anant Ramaswamy, Prabhat Bhargav, Mahesh Goel
Neuroendocrine neoplasms (NENs) are classified as neuroendocrine tumors (NETs), neuroendocrine carcinomas (NECs), and mixed neuroendocrine and nonneuroendocrine neoplasms (MiNENs) according to World Health Organization classification. We present our experience of NENs of the gallbladder (GB) from a high-volume cancer hospital.
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Liver resection is superior to tumor ablation in patients with multifocal hepatocellular carcinoma J. Surg. Oncol. (IF 2.5) Pub Date : 2024-02-09 Hanna Kakish, Mohammed O. Suraju, Erik S. Davis, Abhinav Seth, Yong K. Kwon, Hassan Aziz
The management of T2 multifocal hepatocellular carcinoma (MHCC) is controversial, and the comparative impact of liver resection (LR) versus tumor ablation (TA) on survival continues to be debated. The aim of our study was to examine short- and long-term survival for LR and TA in a nationally representative cohort. We hypothesized that patients who underwent LR would have improved survival.
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Gray oncologic areas J. Surg. Oncol. (IF 2.5) Pub Date : 2024-02-06 Hilde M. Buiting, Gabe S. Sonke
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest.
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The improvement of postoperative blood pressure and associated factors in patients with hormone-negative adrenal adenoma and hypertension J. Surg. Oncol. (IF 2.5) Pub Date : 2024-02-06 Jiaxing Sun, Yingchun Dong, Hanbo Wang, Xudong Guo, Ning Suo, Shangjian Li, Xiangbin Ren, Shaobo Jiang
To investigate the effect of adrenal surgery on blood pressure (BP) improvements in patients with hormone-negative adrenal adenoma (HNA) concomitant with hypertension and analyze associated prognostic factors.
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Impact of deep muscle invasion on nodal status and survival in patients with pT2 esophageal squamous cancer J. Surg. Oncol. (IF 2.5) Pub Date : 2024-02-05 Cheng-Yi Yan, Yi-Min Gu, Gui-Dong Shi, Qi-Xin Shang, Han-Lu Zhang, Yu-Shang Yang, Wen-Ping Wang, Yong Yuan, Long-Qi Chen
Whether T2 esophageal squamous cell carcinoma should be subclassified remains controversial. We aimed to investigate the impact of the depth of muscularis propria invasion on nodal status and survival outcomes.
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Postoperative infectious complications worsen oncologic outcomes following pancreaticoduodenectomy for pancreatic ductal adenocarcinoma J. Surg. Oncol. (IF 2.5) Pub Date : 2024-02-05 Hussein H. Khachfe, Abdulrahman Y. Hammad, Samer AlMasri, Ibrahim Nassour, Rudy ElAsmar, Hao Liu, Annissa de Silva, Jasmine Kraftician, Kenneth K. Lee, Amer H. Zureikat, Alessandro Paniccia
Pancreaticoduodenectomy (PD) remains the only curative option for patients with pancreatic adenocarcinoma (PDAC). Infectious complications (IC) can negatively impact patient outcomes and delay adjuvant therapy in most patients. This study aims to determine IC effect on overall survival (OS) following PD for PDAC.
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The application of three-dimensional custom-made prostheses in chest wall reconstruction after oncologic sternal resection J. Surg. Oncol. (IF 2.5) Pub Date : 2024-02-04 Chengxin Liu, Haipeng Sun, Feng Lin
As one of the cutting-edge advances in the field of reconstruction, three-dimensional (3D) printing technology has been constantly being attempted to assist in the reconstruction of complicated large chest wall defects. However, there is little literature assessing the treatment outcomes of 3D printed prostheses for chest wall reconstruction. This study aimed to analyze the surgical outcomes of 3D
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Patient reported outcomes after multivisceral resection for advanced rectal cancers in female patients J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-30 Mufaddal Kazi, Katyayani Choubey, Pooja Patil, Dushyant Jaiswal, Sejal Ajmera, Ashwin Desouza, Avanish Saklani
Multivisceral resections for rectal cancer can lead to long-term functional disturbances. This study aims to evaluate the quality-of-life outcomes in female patients who underwent multivisceral resection for rectal cancer, specifically focusing on urinary and sexual functions.
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Internal hemipelvectomy: A single institution's learning curve and longitudinal experience J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-29 Rajko S. Vucicevic, Athan G. Zavras, Michael P. Fice, Zeeshan A. Khan, Charles Gusho, Matthew Gasparro, Steven Gitelis, Alan Blank, Matthew W. Colman
Wide margin resection for pelvic tumors via internal hemipelvectomy is among the most technically challenging procedures in orthopedic oncology. As such, surgeon experience and technique invariably affect patient outcomes. The aim of this clinical study was to assess how an individual surgeon's experiences and advancements in technology and techniques in the treatment of internal hemipelvectomy have
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Clinical outcomes in patients with adamantinoma: Report from the bone and soft tissue tumor registry in Japan J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-23 Junya Shimizu, Makoto Emori, Yasutaka Murahashi, Akira Kawai, Atsushi Teramoto
Adamantinomas are rare malignant bone tumors. Due to their low incidence, there are few reports on the clinical results of adamantinoma.
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Seroma formation after mastectomy: A systematic review and network meta-analysis of different flap fixation techniques J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-21 Merel A. Spiekerman van Weezelenburg, Jean H. T. Daemen, Sander M. J. van Kuijk, Elisabeth R. M. van Haaren, Alfred Janssen, Yvonne L. J. Vissers, Geerard L. Beets, James van Bastelaar
Flap fixation is the most promising solution to prevent seroma formation after mastectomy. In this systematic review with network meta-analysis (NMA), three different techniques were compared. The NMA included 25 articles, comprising 3423 patients, and revealed that sutures are superior to tissue glue in preventing clinically significant seroma. In addition, running sutures seemed to be superior to
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Rates of breast reconstruction uptake and attitudes toward breast cancer and survivorship among south asians: A literature review J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-21 Prottusha Sarkar, Kristin N. Huffman, Tokoya Williams, Avneet Deol, Isabella Zorra, Tarifa Adam, Rachel Donaldson, Umer Qureshi, Karan Gowda, Robert D. Galiano
Our aim in this review was to ascertain rates of breast reconstruction among South Asian patients and identify attitudes towards breast cancer, survivorship, and breast reconstruction. Mastectomy rates for South Asian patients ranged from 52% to 77% and reconstruction following mastectomy varied from 0% to 14%. A negative perception of cancer, fears of social isolation, and taboos around breasts can
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Recurrence-risk stratification using the Beppu score and selection of perioperative chemotherapy for colorectal liver metastases J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-18 Toru Beppu, Kensuke Yamamura, Katsunori Imai, Hiromitsu Hayashi, Yuji Miyamoto
The annual postoperative disease-free survival for colorectal liver metastases can be easily estimated by weighting six preoperative clinical parameters (Beppu score). We identified three recurrence-risk stratification groups: the low (≤6 points), moderate (7–10 points), and high-risk (≥11 points). For low-, moderate-, and high-risk patients, hepatectomy alone, hepatectomy with adjuvant chemotherapy
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Myofibroblastic cancer-associated fibroblast subtype heterogeneity in pancreatic cancer J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-17 Joseph F. Kearney, Hannah E. Trembath, Priscilla S. Chan, Ashley B. Morrison, Yi Xu, Chang Fei Luan, Ian C. McCabe, Sandra A. Zarmer, Hong Jin Kim, Xianlu L. Peng, Jen Jen Yeh
Pancreatic ductal adenocarcinoma (PDAC) has a fibrotic stroma that has both tumor-promoting and tumor-restraining properties. Different types of cancer-associated fibroblasts (CAFs) have been described. Here, we investigated whether CAFs within the same subtype exhibit heterogeneous functions.
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Contrast-enhanced ultrasonography as an adjunctive method to ICG lymphography for functional lymphaticovenous anastomosis J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-14 Young Woong Mo, Seung Jun Lee, Dong Won Lee, Won Jai Lee, Sang Hee Im, Young Chul Suh
Indocyanine green (ICG) lymphography is the reference standard for evaluating lymphedema stage and identifying lymphatic vessels. However, the penetration depth was limited to 1–2 cm from the skin surface. This prospective study compares clinical outcomes following lymphaticovenous anastomoses (LVA) in patients with upper and lower limb lymphedema using contrast-enhanced ultrasonography (CEUS) with
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To study the survival analysis and recurrence pattern in women treated for breast cancer: Retrospective study, a tertiary cancer center experience from Sub-Himalayan Region of India J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-14 Shivangi Sundram, Sourabh Nandi, Anshika Arora, Sunil Saini
Breast cancer is a leading health concern in India, comprising 25% of female cancers with significant mortality. This study was conducted at the Cancer Research Institute in the Northern Sub-Himalayan region of India from 2016 to 2021, evaluated 674 breast cancer cases to analyze factors that influence recurrence.
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A precise approach to robotic intracorporeal rectal transection and hand-sewn purse-string anastomosis for low anterior resection J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-14 Paulo. R. Stevanato Filho, Tiago S. Bezerra, Tomas M. D. M. Marques, Rebeca H. Nahime, Renata M. Takahashi, Wilson T. Nakagawa, Ademar Lopes, Samuel Aguiar
This study presents a new technique for robotic-assisted intracorporeal rectal transection and hand-sewn anastomosis for low anterior resection that overcomes some limitations of conventional techniques. By integrating the advantages of the robotic platform, ensuring standardized exposure during rectal transection, and emphasizing the importance of avoiding complications associated with staple crossings
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Larger stem to bone diameter ratio predicts lower cemented endoprosthesis failure J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-14 Yazan Kadkoy, Joseph A. Ippolito, Gregory Schneider, Jennifer Thomson, Claire Park, Rosamaria Dias, Kathleen S. Beebe, Francis R. Patterson, Joseph Benevenia
With continued advances in treatment options, patients with endoprosthetic reconstruction are living longer and consequently relying upon their devices for a longer duration. Major causes of endoprosthesis failure include aseptic loosening and mechanical failure. In the setting of tumor resection, loss of bone stock and use of radiation therapy increase the risk for these complications. As such, considerations
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Impact of neoadjuvant therapy on nodal harvest in clinical stage III rectal cancer: Establishing optimum cut-offs by disease response J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-14 Chase J. Wehrle, Kimberly Woo, Jenny Chang, Maysoon Gamaleldin, Reece DeHaan, Fadi Dahdeleh, Seth Felder, David R. Rosen, Bradley Champagne, Scott R. Steele, Samer A. Naffouje
A minimum lymph node harvest (LNH) of 12 is the current standard for appropriate nodal staging in resectable rectal cancer. However, the rise of neoadjuvant chemoradiation (NCRT) and total neoadjuvant therapy (TNT) has been associated with decreasing number of LNH. We hypothesize that as tumor response to neoadjuvant therapy increases, the optimum for LNH to achieve appropriate nodal staging should
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Establishing the clinical relevance of grade A post-hepatectomy liver failure J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-15 Dominic J. Vitello, Dhavan Shah, Bona Ko, Brian C. Brajcich, Xane D. Peters, Ryan P. Merkow, Henry A. Pitt, David J. Bentrem
The International Study Group of Liver Surgery's criteria stratifies post-hepatectomy liver failure (PHLF) into grades A, B, and C. The clinical significance of these grades has not been fully established.
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Characterization of natural killer and cytotoxic T-cell immune infiltrates in pancreatic ductal adenocarcinoma J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-09 Julia Persky, Sylvia M. Cruz, Morgan A. Darrow, Sean J. Judge, Yueju Li, Richard J. Bold, Anthony N. Karnezis, Karen E. Matsukuma, Lihong Qi, Robert J. Canter
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with poor response to systemic therapies, including immunotherapy. Given the immunotherapeutic potential of natural killer (NK) cells, we evaluated intratumoral NK cell infiltrates along with cytotoxic T cells in PDAC to determine their association with patient outcomes.
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Comparison of epidural infusion versus intrathecal morphine block as part of enhanced recovery after open pancreatoduodenectomy J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-07 Jessica C. El-Mallah, Alicia C. Greene, Taylor J. Clegg, Sejal J. Shah, Saif N. El-Mallah, Charles C. Vining, Matthew E. B. Dixon, June S. Peng
The accepted approach to pain management following open pancreatoduodenectomy (PD) remains controversial, with the most recent enhanced recovery after surgery (ERAS) protocols recommending epidural anesthesia (EA). Few studies have investigated intrathecal (IT) morphine, combined with transversus abdominis plane (TAP) blocks. We aim to compare the different approaches to pain management for open PD
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Minimally invasive versus open gastrectomy for gastric cancer. A pooled analysis of two European randomized controlled trials J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-04 Nicole van der Wielen, Hylke Brenkman, Maarten Seesing, Freek Daams, Jelle Ruurda, Arjen van der Veen, Donald L. van der Peet, Jennifer Straatman, Richard van Hillegersberg
Minimally invasive techniques have shown better short term and similar oncological outcomes compared to open techniques in the treatment of gastric cancer in Asian countries. It remains unknown whether these outcomes can be extrapolated to Western countries, where patients often present with advanced gastric cancer.
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Drain-free mastectomy and flap fixation: The interim analysis of a randomized controlled noninferiority trial J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-04 Merel A. Spiekerman van Weezelenburg, Lisa de Rooij, Loeki Aldenhoven, Sander M. J. van Kuijk, Elisabeth R. M. van Haaren, Alfred Janssen, Yvonne L. J. Vissers, Geerard L. Beets, James van Bastelaar
Flap fixation after mastectomy has proven to be one of the most promising solutions to reduce seroma formation. Drain placement remains standard practice in many clinics, even though this may be redundant after flap fixation.
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Short-term outcomes of laparoscopic and robotic distal gastrectomy for gastric cancer: Real-world evidence from a large-scale inpatient database in Japan J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-04 Nao Hondo, Yuta Yamamoto, Takayo Nakabe, Tetsuya Otsubo, Masato Kitazawa, Satoshi Nakamura, Makoto Koyama, Satoru Miyazaki, Masahiro Kataoka, Yuji Soejima
Robotic distal gastrectomy (RDG) has been widely performed throughout Japan since it became insured in 2018. This study aimed to evaluate the short-term outcomes of RDG and laparoscopic distal gastrectomy (LDG) for gastric cancer using real-world data.
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The relationship between DNA mismatch repair gene and other prognostic parameters in pancreatic adenocarcinoma J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-04 Nil Urganci, Nuray Kepil, Sefa Ergun, Oguz Kaan Bakkaloglu
The aim of the study was to determine DNA mismatch repair (MMR) proteins by immunohistochemically using MLH1, MSH2, MSH6, and PMS2 antibodies in patients diagnosed as pancreatic ductal adenocarcinoma and to assess its relationship with histopathological and clinical prognostic parameters. Fifty cases with a diagnosis of pancreatic ductal adenocarcinoma who underwent surgical resection, were included
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Association of omental pedicled flap with anastomotic leak following low anterior resection for rectal cancer J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-02 Danish Ali, Maria Syed, Adriana C. Gamboa, Alexander T. Hawkins, Scott E. Regenbogen, Jennifer Holder-Murray, Matthew Silviera, Aslam Ejaz, Glen C. Balch, Aimal Khan
Anastomotic leak following colorectal anastomosis adversely impacts short-term, oncologic, and quality-of-life outcomes. This study aimed to assess the impact of omental pedicled flap (OPF) on anastomotic leak among patients undergoing low anastomotic resection (LAR) for rectal cancer using a multi-institutional database.
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Highly complex liver resections: Exploring the boundaries of feasibility and safety J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-01 Ron Pery, Niv Pencovich, Rony Eshkenazy, Ido Nachmany
In select clinical scenarios, advanced techniques for volume manipulation and vascular reconstruction are needed for complete hepatic tumor removal. These highly complex liver resections (HCLRs) entail a heightened risk of severe complications. Here, we describe the results of HCLR performed in a 3-year time period.
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Pilot study of a telehealth intervention for personalized self-management for eating symptoms after gastroesophageal cancer surgery J. Surg. Oncol. (IF 2.5) Pub Date : 2024-01-01 Jae Y. Kim, Madeleine Love, Yanghee Woo, Beatriz Campos, Adern Yu, Justin Chang, Loretta Erhunmwunsee, Robert S. Krouse, Laleh Melstrom, Virginia Sun
Following gastric and esophageal cancer surgery, patients often experience significant, prolonged eating-related symptoms. One promising approach to help patients improve their eating-related quality of life (QOL) is through self-management coaching to aid in diet modification. We performed a randomized pilot study of a nutritionist-led telehealth intervention for the self-management of eating after
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Association between social determinants of health and delayed postoperative adjuvant therapy among patients undergoing resection of pancreatic cancer J. Surg. Oncol. (IF 2.5) Pub Date : 2023-12-27 Zayed Rashid, Muhammad M. Munir, Selamawit Woldesenbet, Muhammad M. M. Khan, Mujtaba Khalil, Yutaka Endo, Diamantis I. Tsilimigras, Mary Dillhoff, Aslam Ejaz, Timothy M. Pawlik
Pancreatic cancer (PDAC) requires a multimodality approach. We sought to define the association between social determinants of health (SDOH) and delayed or nonreceipt of adjuvant chemotherapy (aCT) among patients undergoing PDAC resection.
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Sarcoma in patients with Lynch syndrome and response to immunotherapy J. Surg. Oncol. (IF 2.5) Pub Date : 2023-12-27 Michael S. Shehata, Serena Y. Lofftus, Joon Y. Park, Arun S. Singh, Noah C. Federman, Fritz C. Eilber, Joseph G. Crompton, Tyler R. McCaw
Lynch syndrome (LS) is an autosomal dominant genetic predisposition to multiple malignancies and is characterized by deficient DNA mismatch repair. Increased incidence of sarcomas is not formally ascribed to LS; however, increasing evidence suggests a preponderance of these malignancies in affected families. Sarcomas typically possess a low tumor mutational burden and incite a poor immune infiltrate
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Impact of autotransfusion on recurrence of colorectal cancer liver metastasis: Long-term follow-up of patients undergoing curative intent hepatectomy J. Surg. Oncol. (IF 2.5) Pub Date : 2023-12-27 Chase J. Wehrle, Breanna Perlmutter, Hanna Hong, Jenny Chang, Kathryn A. Stackhouse, Rob Naples, M. Shanaz Hossain, Daniel Joyce, Robert Simon, Jaekeun Kim, Samer A. Naffouje, Federico Aucejo, David C. H. Kwon, R. Matthew Walsh, Toms Augustin
Colorectal cancer liver metastasis (CRLM) occurs in upto 50% of cases and drives patient outcomes. Up-front liver resection is the treatment of choice in resectable cases. There is no consensus yet established as to the safety of intraoperative autotransfusion in liver resection for CRLM.
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Prognostic significance of positive lymph node regression grade to neoadjuvant chemoradiation for esophageal squamous cell carcinoma J. Surg. Oncol. (IF 2.5) Pub Date : 2023-12-20 Zhou Yehan, Liu Ying, Guo Peng, Huang Zongyao, Zhou Chengmin, Yang Hong, Qin Sheng, Zhu Jie, Wang Yi, Leng Xuefeng, He Wenwu, Wang Qifeng, Liu Yang
To assess the relationship between metastatic lymph node (LN) responder status and recurrence-free survival (RFS) in patients undergoing neoadjuvant chemoradiotherapy (NCRT).
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Poor prognosis of young male patients with stage III colorectal cancer: A multicenter retrospective study J. Surg. Oncol. (IF 2.5) Pub Date : 2023-12-19 Kazuaki Okamoto, Kazuhito Sasaki, Hiroaki Nozawa, Koji Murono, Shigenobu Emoto, Shinichi Yamauchi, Kenichi Sugihara, Soichiro Ishihara
The number of young patients with colorectal cancer (CRC) is increasing. However, sex-dependent differences in the prognosis of young CRC remain unknown.
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Can we let our patients sleep in the hospital? A randomized controlled trial of a pragmatic sleep protocol in surgical oncology patients J. Surg. Oncol. (IF 2.5) Pub Date : 2023-12-19 Kathrine Kelly, Hordur Kolbeinsson, Lauren M. Blanck, Mariam Khan, Roxanne Kyriakakis, M. Mura Assifi, G. Paul Wright, Mathew Chung
Postoperative inpatients experience increased stress due to pain and poor restorative sleep than non-surgical inpatients.
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Moving into the modern era of molecular classification for endometrial cancer J. Surg. Oncol. (IF 2.5) Pub Date : 2023-12-15 Christian Dagher, Ying L. Liu, Jennifer J. Mueller, Britta Weigelt
The molecular subtypes of endometrial carcinoma (EC) were first described by The Cancer Genome Atlas (TCGA) a decade ago. Using surrogate approaches, the molecular classification has been demonstrated to be prognostic across EC patients and to have predictive implications. Starting in 2020, the molecular classification has been incorporated into multiple guidelines as part of the risk assessment and
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The platelet-to-lymphocyte ratio is a complementary prognostic factor to tumor markers in predicting early recurrence of hepatocellular carcinoma after hepatectomy J. Surg. Oncol. (IF 2.5) Pub Date : 2023-12-17 Kiyotaka Hosoda, Kentaro Umemura, Akira Shimizu, Koji Kubota, Tsuyoshi Notake, Noriyuki Kitagawa, Hiroki Sakai, Hikaru Hayashi, Koya Yasukawa, Yuji Soejima
The usefulness of inflammation-based prognostic scores for early recurrence (ER) after hepatectomy for hepatocellular carcinoma has rarely been reported. This study aimed to evaluate the potential of inflammation-based prognostic scores as predictors of ER and their relationship with tumor markers.
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Oligometastases: Incorporate the patient perspective to ensure optimal treatment and care J. Surg. Oncol. (IF 2.5) Pub Date : 2023-12-15 Hilde M. Buiting, Yvette van der Linden, Tessa G. Steenbruggen, Eva E. Bolt, Winan van Houdt, Gabe S. Sonke
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest.
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An alternative robotic approach to precise colorectal transection and single-staple anastomosis in high anterior resection: Video correspondence J. Surg. Oncol. (IF 2.5) Pub Date : 2023-12-14 Paulo R. Stevanato Filho, Tiago S. Bezerra, Tomas M. D. M. Marques, Rebeca H. Nahime, Renata M. Takahashi, Wilson T. Nakagawa, Ademar Lopes, Samuel Aguiar
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest.
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Outcomes of incidental versus non-incidental T2 gallbladder cancer: A single-institute experience of 425 cases J. Surg. Oncol. (IF 2.5) Pub Date : 2023-12-13 Shraddha Patkar, Aditya Kunte, Vikram Chaudhari, Mahesh Goel
Up to 60% of incidentally detected gallbladder cancers (GBCs) have a primary stage of pathologic T2 stage (pT2), defined by invasion of the peri-adventitial tissue by the tumour, a plane breached during a simple cholecystectomy. This study assesses the impact of incidental detection of pT2 GBCs on survival outcomes.
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Risk factors for local recurrence of upper extremity desmoid tumors J. Surg. Oncol. (IF 2.5) Pub Date : 2023-12-10 Hayley Denwood, Marcos R. Gonzalez, Alisha Sodhi, Joseph Werenski, Marilee Clunk, Erik T. Newman, Santiago A. Lozano-Calderón
Upper extremity (UE) desmoid tumors are locally aggressive neoplasms with high recurrence rates. Our study sought to analyze the demographics and treatment strategies of UE desmoid tumors and identify risk factors for recurrence.
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Clinical, functional, and patient-reported outcomes of radial forearm versus anterolateral thigh free tissue transfer for reconstruction of glossectomy defects J. Surg. Oncol. (IF 2.5) Pub Date : 2023-12-10 Kevin K. Zhang, Francis D. Graziano, Zack Cohen, Louise Cunningham, Barkat Ali, Janet Coleman-Belin, Minji Kim, Kathryn Haglich, Jennifer R. Cracchiolo, Evan Matros, Farooq Shahzad, Jonas A. Nelson, Robert J. Allen
There is a lack of literature of health-related quality of life endpoints for radial forearm (RF) versus anterolateral thigh (ALT) free flap reconstruction for glossectomy defects. Our goal was to perform a comprehensive evaluation of clinical, functional, and quality of life outcomes after glossectomy reconstruction using a RF or ALT flap.