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Corrigendum to “Long-term changes in serum squamous cell carcinoma antigen levels after surgery in patients with sinonasal inverted papilloma” [Auris Nasus Larynx volume 49 (2022) 697–702] Auris Nasus Larynx (IF 1.7) Pub Date : 2024-01-03 Yoshiaki Kitamura, Seiichiro Kamimura, Tatsuya Fujii, Ryo Kanamura, Junya Fukuda, Eiji Kondo, Takahiro Azuma, Go Sato, Noriaki Takeda
Abstract not available
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From research to clinical practice: An analysis of 226 Hz-probe tone tympanometry to identify otitis media with effusion in children Auris Nasus Larynx (IF 1.7) Pub Date : 2023-12-21 Kátia de Freitas Alvarenga, Alana Ribeiro de Melo, Marina Saes Rays, Alice Andrade Lopes Amorim, Lilian Cássia Bórnia Jacob, Eliene Silva Araújo
Objectives (1) To calculate the sensitivity and specificity of tympanometry with a 226 Hz probe to identify middle ear condition in children; (2) To propose the intersection range of static compliance and tympanometric peak pressure values obtained in ears with and without middle ear effusion. Methods 224 children's ears without middle ear alteration, with a mean age of 1 year and 4 months (GI), and
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Vestibular compensation: Neural mechanisms and clinical implications for the treatment of vertigo Auris Nasus Larynx (IF 1.7) Pub Date : 2023-12-19 Noriaki Takeda, Kazunori Matsuda, Junya Fukuda, Go Sato, Atsuhiko Uno, Tadashi Kitahara
After unilateral peripheral vestibular lesions, the neural activity of neurons in the ipsi-lesional medial vestibular nucleus (ipsi-MVe) are markedly decreased, resulting in static and dynamic asymmetries of the vestibulo-ocular and vestibulo-spinal reflexes. Consequently, static vestibular symptoms such as spontaneous nystagmus and postural deviation and dynamic vestibular symptoms such as oscillopsia
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Long term effects of cochlear implant surgery on vestibular system in pediatric population Auris Nasus Larynx (IF 1.7) Pub Date : 2023-12-08 Ata Alperen Erşahan, Hasan Mervan Değer, Merve Durgut, Murat Öztürk, Fatih Mutlu
Objective The aim was to evaluate the vestibular system of children who had undergone cochlear implant surgery and to compare them with the healthy population by vestibulo-ocular reflex (VOR) gains in unilateral and bilateral implant users, with the implants both on and off. Methods Patients older than 5 years who had undergone cochlear implant surgery between 2012 and 2020 and who were cochlear implant
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Efficacy, safety, and tissue penetration of solithromycin in Japanese patients with otorhinolaryngological infections Auris Nasus Larynx (IF 1.7) Pub Date : 2023-12-07 Yuichi Kurono, Fumiyo Kudo, Akira Watanabe, Takahiro Yamatake, Satoshi Shimada, Kenji Suzuki
Objective To assess the efficacy, safety, and tissue penetration of solithromycin for the treatment of otorhinolaryngological infections, we conducted three studies: a tissue penetration study with patients scheduled to undergo otorhinolaryngological tissue removal, an open-label study comprising patients with otitis media, pharyngitis, laryngitis, and tonsillitis, and a non-inferiority study compared
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Sinonasal microbiome and inflammatory profiles in fungal ball and chronic rhinosinusitis Auris Nasus Larynx (IF 1.7) Pub Date : 2023-12-06 Daeyoung Roh, Ji-Hyeon Shin, Soo Whan Kim, Sung Won Kim, Byung-Guk Kim, Jin-Hee Cho, Yong-Jin Park, Do Hyun Kim
Objective Fungal balls (FB) are the main form of non-invasive fungal rhinosinusitis found in immunocompetent hosts. Bacterial coinfection affects clinical symptoms. We investigated the sinonasal microbiome and inflammatory profiles in FB and chronic rhinosinusitis (CRS) patients. Methods Thirty-three participants were prospectively recruited. Nasal swab samples and sinonasal tissues were collected
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Peritonsillar abscess caused by Mycoplasma hominis and Fusobacterium necrophorum following oral sex Auris Nasus Larynx (IF 1.7) Pub Date : 2023-12-02 Hiroshi Morioka, Hideyuki Kaida, Mitsuru Nishio, Kenji Suga
Mycoplasma hominis is a bacterium that colonizes the genital tract of some females and males, as well as their respiratory tracts. Although only two cases of deep neck infection have been reported, the associations between the onset and sexual intercourse have not been reported. A healthy 19-year-old female was diagnosed with a left peritonsillar abscess. The patient had sexual intercourse with a new
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Understanding hereditary hemorrhagic telangiectasia: From genetic anomalies to systemic manifestations, quality of life, and epistaxis management—Exploring the otolaryngologist's integral role Auris Nasus Larynx (IF 1.7) Pub Date : 2023-11-25 Masaki Hayama, Yohei Maeda, Sho Obata, Takeshi Tsuda, Kazuya Takeda, Takeo Nishida, Hidenori Inohara
Hereditary hemorrhagic telangiectasia (HHT), also known as Osler–Rendu–Weber syndrome, is a rare autosomal dominant disorder characterized by vascular malformations. This comprehensive review aimed to provide an overview and summarize various aspects of HHT, including the genetic abnormalities, complications associated with visceral arteriovenous malformations (AVMs), prognosis of HHT, quality of life
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Lipids and sudden sensorineural hearing loss: A bidirectional two-sample Mendelian randomization analysis Auris Nasus Larynx (IF 1.7) Pub Date : 2023-11-22 Kunlin Pu, Li Li, Yan Qiu, Hongmei Song
Objective While numerous observational studies have indicated an association between lipids and Sudden Sensorineural Hearing Loss (SSNHL), it remains uncertain whether dyslipidemia serves as a causal risk factor for SSNHL. Our objective is to elucidate the potential causal relationship between lipid levels and SSNHL through Mendelian randomization analysis. Methods The primary and secondary lipid data
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Effectiveness of FEES with artificial intelligence-assisted computer-aided diagnosis Auris Nasus Larynx (IF 1.7) Pub Date : 2023-11-18 Mitsuyoshi Imaizumi, Weihao Weng, Xin Zhu, Shigeyuki Murono
Objectives FEES is a standard procedure for diagnosing dysphagia. However, appropriate evaluation of FEES findings is difficult for inexperienced evaluators. Recent progress in deep learning has highlighted the use of artificial intelligence-assisted computer-aided diagnosis (AI-assisted CAD) in medical applications. We investigated the detection accuracy of FEES findings evaluated by inexperienced
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Useful combination of Gehanno method, polyglycolic acid sheet and fibrin glue for prevention of postoperative dysfunction after soft palate resection with TORS Auris Nasus Larynx (IF 1.7) Pub Date : 2023-11-18 Kiyoaki Tsukahara, Kenji Hanyu, Akira Shimizu
Oropharyngeal cancer requiring combined resection of the soft palate is relatively out of indication for transoral robotic surgery (TORS) due to postoperative functional problems. We report the case of a patient with oropharyngeal cancer in which half of the soft palate was resected, and good function was maintained using the Gehanno method, polyglycolic acid (PGA) sheet and fibrin glue. The patient
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New insights into chronic rhinosinusitis associated with IgG4-related disease Auris Nasus Larynx (IF 1.7) Pub Date : 2023-11-14 Kenichi Takano, Ryuta Kamekura, Tsuyoshi Okuni, Keisuke Yamamoto
IgG4-related disease (IgG4-RD) is a chronic inflammatory disorder characterized by elevated IgG4 serum levels, abundant IgG4-positive plasmacyte infiltration, and fibrosis of various organs, including the head and neck. We aimed to provide an overall review of IgG4-RD in the sinonasal region and propose a novel entity and criteria of chronic rhinosinusitis (CRS) associated with IgG4-RD as “IgG4-CRS
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Targeted next-generation sequencing of Japanese patients with sinonasal mucosal melanomas identifies frequent NRAS and CTNNB1 mutations Auris Nasus Larynx (IF 1.7) Pub Date : 2023-11-10 Nayuta Tsushima, Satoshi Kano, Kanako C. Hatanaka, Takayoshi Suzuki, Seijiro Hamada, Hiroshi Idogawa, Yuji Nakamaru, Masanobu Suzuki, Yutaka Hatanaka, Akihiro Homma
Objective Mucosal melanoma is a rare malignancy; however, the reported incidence rate of mucosal melanoma is higher in Asians than in Caucasians. Sinonasal mucosal melanoma (SNMM) is an aggressive malignancy with a poor prognosis due to distant metastasis. Systemic therapy with BRAF inhibitor and MEK inhibitor is one of the standards of care for cutaneous melanoma patients with BRAF V600 mutations
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Central node dissection from the perspective of lateral neck node metastasis in papillary thyroid carcinoma Auris Nasus Larynx (IF 1.7) Pub Date : 2023-11-07 Masataka Taniuchi, Ryo Kawata, Tetsuya Terada, Masaaki Higashino, Teruhito Aihara, Tsuyoshi Jinnin
Objectives Controversy exists on how to handle central lymph nodes in papillary thyroid carcinoma, particularly regarding indications for prophylactic central neck dissection (CND). Central node metastases are more difficult to diagnose preoperatively than lateral node metastases. Methods We enrolled 493 patients with papillary thyroid carcinoma treated at our department in the past 22 years. Metastatic
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Safety and efficacy of high tracheostomy with inferior retraction of the thyroid isthmus Auris Nasus Larynx (IF 1.7) Pub Date : 2023-11-04 Daisuke Iokura, Yusuke Okanoue, Shuya Otsuki, Kengo Oe, Kuniaki Takata, Akihito Tarui, Tsuyoshi Kojima
Objective In typical surgical tracheostomy, the thyroid isthmus is divided or retracted superiorly and preserved. However, at our institution, the thyroid isthmus is retracted inferiorly and preserved. Thereafter, a tracheal incision is made above the thyroid isthmus. This method, hereinafter defined as high tracheostomy, has the advantage of facilitating immediate access to the trachea in a superficial
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Risk factors for occurrence and progression of external auditory canal cholesteatoma Auris Nasus Larynx (IF 1.7) Pub Date : 2023-11-02 Saori Seki, Tomonori Sugiyama, Saori Kikuchi, Yukiko Iino
Objective External auditory canal cholesteatoma (EACC) is characterized by retained squamous debris within the external canal and variable amounts of localized bone destruction. The etiology of primary EACC remains incompletely understood. This study was conducted to analyze the clinical features and backgrounds of patients with primary EACC and to clarify the risk factors for the occurrence and progression
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Effects on hearing after long-term use of iron chelators in beta-thalassemia: Over twenty years of longitudinal follow-up Auris Nasus Larynx (IF 1.7) Pub Date : 2023-10-29 Mirko Aldè, Umberto Ambrosetti, Marianna Giuditta, Elena Cassinerio, Gioia Piatti
Objective The role of iron chelation in causing hearing loss (HL) is still unclear. The present study assessed the prevalence of HL among transfusion-dependent thalassemia (TDT) patients who underwent audiological follow-up over a 20-year period. Methods We retrospectively analyzed clinical records and audiological tests from January 1990 (T0) to December 2022 (T22) of a group of TDT patients who received
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Outcomes of regenerative treatment for over 200 patients with tympanic membrane perforation Auris Nasus Larynx (IF 1.7) Pub Date : 2023-10-25 Rie Kanai, Shin-ichi Kanemaru, Tomoya Yamaguchi, Shin-ichiro Kita, Toru Miwa, Akiko Kumazawa, Jun Okamoto, Misaki Yoshida, Hiroyuki Harada, Toshiki Maetani
Objective To evaluate outcomes of a regenerative treatment (RT) for over 200 patients with tympanic membrane perforation (TMP). The RT-TMP method involves a gelatin sponge, basic fibroblast growth factor (bFGF) and fibrin glue. Methods The study population included 216 patients and 234 ears (male: female =100:116; age 1–93 years). All enrolled patients were treated with RT-TMP in which TMP edges were
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The construction and validation of prognostic prediction model for sudden sensorineural hearing loss in middle-aged and elderly people Auris Nasus Larynx (IF 1.7) Pub Date : 2023-10-21 Zhiqiang Zhang, Changxu Yu, Xueyan Wang, Sitong Ge, Guanhong Zhai, Shurui Si, Tianyi Ma, Fuyao Li, Zhezhu Cui, Xianghua Jin, Yulian Jin
Objective Idiopathic sudden sensorineural hearing loss (ISSNHL), as an otologic emergency, is commonly encountered and its prevalence has been climbing every year recently. To our knowledge, the prognosis of middle-aged and elderly patients is worse than that of young patients. Previous researches mainly focused on the adult population, which was considered as prognostic models who performed hearing
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Estimated incidence and characteristics of vestibular neuritis in Japan: A nationwide survey Auris Nasus Larynx (IF 1.7) Pub Date : 2023-10-13 Shinichi Iwasaki, Takuya Kawahara, Takenori Miyashita, Susumu Shindo, Masahito Tsubota, Aki Inoue, Kishiko Sunami, Hideo Shojaku
Objective To assess the annual incidence of vestibular neuritis (VN) in the Japanese population. Methods We conducted a mail-based survey targeting otolaryngologic clinics and hospitals across Japan to estimate the annual number of patients who were newly-diagnosed with VN during the one-year period of 2021. Using a stratified sampling method, we selected 1,107 departments and asked them to report
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Clinical characteristics in Japanese patients with chronic rhinosinusitis who underwent endoscopic sinus surgery Auris Nasus Larynx (IF 1.7) Pub Date : 2023-10-13 Natsuki Inoue, Tomomitsu Hirota, Akihiro Hatano, Mika Nakano, Daiki Nakashima, Tsuguhisa Nakayama, Mayumi Tamari, Mamoru Yoshikawa
Objective There is heterogeneity in the pathophysiology of chronic rhinosinusitis (CRS). Obtaining a detailed understanding of patient profiles in specific regions can provide valuable information not only for clinical practice but also future research plans. The aim of this study was to investigate the characteristics of patients who underwent endoscopic sinus surgery (ESS) for CRS. Methods This retrospective
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Botulinum toxin injection for abductor spasmodic dysphonia under cervical ultrasonography guidance Auris Nasus Larynx (IF 1.7) Pub Date : 2023-10-12 Chikako Kunieda, Fumiaki Nin, Toshimitsu Ohashi, Kiyohito Hosokawa, Yusuke Watanabe, Takenori Ogawa, Tomohiro Mori, Takeharu Kanazawa
Ultrasound (US) imaging effectively provides real-time anatomical information for clinical examinations. In otolaryngology, US imaging can visualize laryngeal muscles as well as cervical muscles. Here we present the case where US imaging was used while injecting botulinum toxin (BT) for the treatment of abductor spasmodic dysphonia, which provided definite results. We could visualize not only the injection
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Artificial intelligence-based diagnosis of the depth of laryngopharyngeal cancer Auris Nasus Larynx (IF 1.7) Pub Date : 2023-10-12 Kohei Yumii, Tsutomu Ueda, Daisuke Kawahara, Nobuyuki Chikuie, Takayuki Taruya, Takao Hamamoto, Sachio Takeno
Objective Transoral surgery (TOS) is a widely used treatment for laryngopharyngeal cancer. There are some difficult cases of setting the extent of resection in TOS, particularly in setting the vertical margins. However, positive vertical margins require additional treatment. Further, excessive resection should be avoided as it increases the risk of bleeding as a postoperative complication and may lead
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Improvements in blood IGF-1 and skeletal age following adenotonsillectomy for growth delay in children with obstructive sleep apnea Auris Nasus Larynx (IF 1.7) Pub Date : 2023-10-08 Yuma Yoshioka, Shoji Matsune, Kuwon Sekine, Mariko Ishida, Nozomu Wakayama, Satoshi Yamaguchi, Kimihiro Okubo
Objective In children with obstructive sleep apnea (OSA) who underwent adenotonsillectomy (AT), we measured body height and weight using standard deviation (SD) scores, insulin-like growth factor 1 (IGF-1), and skeletal age using carpal radiography. We then compared these values before and after surgery with the aim of investigating postoperative improvements in growth hormone (GH) deficiency. Methods
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Characteristics of pure tone audiogram in patients with untreated sporadic vestibular schwannoma: Analysis of audiometric shape and interaural differences stratified by age and mode of onset Auris Nasus Larynx (IF 1.7) Pub Date : 2023-10-01 Nobuyoshi Tsuzuki, Tsubasa Kitama, Koichiro Wasano, Takeshi Wakabayashi, Makoto Hosoya, Takanori Nishiyama, Hiroyuki Ozawa, Naoki Oishi
Objective Asymmetric sensorineural hearing loss (ASHL) is the most common symptom of sporadic vestibular schwannoma (VS). However, there is still no universally accepted MRI protocol for diagnosing VS. This study identified the characteristics of pure tone audiogram (PTA) in patients with VS. Methods We conducted a retrospective chart review of patients diagnosed with sporadic unilateral VS. In the
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Near-infrared photoimmunotherapy for salivary duct carcinoma Auris Nasus Larynx (IF 1.7) Pub Date : 2023-09-27 Takuma Makino, Yasuharu Sato, Kensuke Uraguchi, Yuto Naoi, Yujiro Fukuda, Mizuo Ando
In Japan, near-infrared photoimmunotherapy (NIR-PIT) was introduced in 2021 as a treatment option for unresectable recurrent head and neck cancer. The treatment targets the epidermal growth factor receptor (EGFR), which is overexpressed in 80–90 % of head and neck squamous cell carcinoma (HNSCC). NIR-PIT should theoretically show therapeutic efficacy if EGFR is expressed, even in nonsquamous cell carcinomas
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Pathogenesis-based application of biologics for chronic rhinosinusitis: Current and future perspectives Auris Nasus Larynx (IF 1.7) Pub Date : 2023-09-22 Mitsuhiro Okano, Kengo Kanai, Aiko Oka
Chronic rhinosinusitis (CRS) is heterogeneous and contains diverse pathogenesis including type 1, type 2, and/or type 3 inflammation. For severe type 2 CRS especially CRS with nasal polyps (CRSwNP), biologics that target inflammatory molecules have recently been applied along with further changes in the treatment algorithm for CRS. Currently, a completed phase 3 clinical trial for biologics for severe
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Effects of high-dose betahistine on intractable dizziness in patients with uncompensated unilateral vestibulopathy Auris Nasus Larynx (IF 1.7) Pub Date : 2023-09-03 Noriaki Takeda, Go Sato, Kazunori Matsuda, Juichi Ito, Koichi Omori, Yatsuji Ito, Tadashi Kitahara, Izumi Koizuka, Hideo Shojaku, Mamoru Suzuki, Katsumi Doi, Toshihisa Murofushi, Hiroshi Yamashita
Objective In the present study, we examined the effects of high-dose betahistine on dizziness handicap inventory (DHI) scores in patients with unilateral vestibulopathy. Methods An uncontrolled, open-label, multicenter clinical trial was conducted. Fifteen patients with unilateral vestibulopathy, such as vestibular neuritis, who complained of intractable dizziness for more than three months were enrolled
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Surgical results of 29 ears with congenital middle ear anomalies; Microscopic vs. endoscopic ear surgery Auris Nasus Larynx (IF 1.7) Pub Date : 2023-08-28 Taisuke Kobayashi, Mayu Kuzume, Hiroaki Ito, Masahiro Komori, Masamitsu Hyodo
Objective Although congenital middle ear anomalies include various types of ossicular anomalies, all of these can be treated by ossiculoplasty or stapes surgery. Transcanal endoscopic ear surgery (TEES) is a minimally invasive surgical method for middle ear disease with an excellent surgical view that has been widely adopted worldwide. To determine the efficacy of TEES for middle ear anomalies, we
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Translational research in head and neck cancer: Molecular and immunological updates Auris Nasus Larynx (IF 1.7) Pub Date : 2023-08-27 Takumi Kumai, Hirotaka Shinomiya, Hirofumi Shibata, Hideaki Takahashi, Toshihiro Kishikawa, Ryuhei Okada, Shigeharu Fujieda, Masafumi Sakashita
Head and neck squamous cell carcinoma (HNSCC) has a poor prognosis. Each year, approximately 880,000 patients are newly diagnosed with HNSCC worldwide, and 450,000 patients with HNSCC die. Risk factors for developing HNSCC have been identified, with cigarette smoking, alcohol consumption, and viral infections being the major factors. Owing to the prevalence of human papillomavirus infection, the number
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HDR syndrome, detected in the neonatal period by newborn hearing screening Auris Nasus Larynx (IF 1.7) Pub Date : 2023-08-27 Shunsuke Takai, Mika Adachi, Hiyori Takahashi, Masayuki Shirakura, Yohei Honkura, Daisuke Yamauchi, Yukio Katori
Hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome is an autosomal dominant disorder. Because HDR syndrome is caused by haploinsufficiency in GATA3, it exhibits variation in the onset and progression of hearing loss. In previous reports, the automated auditory brainstem response (AABR) was considered insufficient to detect sensorineural hearing loss caused by HDR syndrome. We report a
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Superior canal dehiscence syndrome: A review Auris Nasus Larynx (IF 1.7) Pub Date : 2023-08-26 Mitsuya Suzuki, Yasushi Ota, Taro Takanami, Ryosuke Yoshino, Hiroaki Masuda
Superior canal dehiscence syndrome (SCDS) is a vestibular disorder in which the presence of a pathological third window in the labyrinth causes several vestibular and cochlear symptoms. Herein, we review the diagnostic criteria and treatment of SCDS. The cause of SCDS is considered to be congenital or acquired; however, its etiology is not well known. Symptoms: Vertigo and/or oscillopsia induced by
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Assessment of eosinophilic rhinosinusitis cases that required secondary treatment (biologics or reoperation) during long-term postoperative courses Auris Nasus Larynx (IF 1.7) Pub Date : 2023-08-25 Kosuke Akiyama, Yasushi Samukawa, Hiroshi Hoshikawa
Objective Endoscopic sinus surgery (ESS) is selected as the primary treatment for eosinophilic chronic rhinosinusitis (ECRS). Biologics or reoperation are sometimes required as secondary treatment after ESS. The present study examined the long-term postoperative courses of ECRS cases treated according to the current treatment concept, the frequency of secondary treatment, and its predictive factors
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Evaluation of odor recognition threshold measurement methods in T&T olfactometry: A survey study Auris Nasus Larynx (IF 1.7) Pub Date : 2023-08-11 Kei Hosoya, Taro Komachi, Yohei Maeda, Hitoshi Akazawa, Eriko Ogino, Azusa Yoshida, Kimihiro Okubo, Takaki Miwa
Objective The odor recognition thresholds in T&T olfactometry are measured by either the examiner's judgment of the patients’ odor expression for each standard odor or by the patient's choice of the correct response from an olfactory term table. This study aimed to clarify the correct odor expressions and use of the olfactory term table. Methods A questionnaire was administered to otolaryngologists
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The current findings in eosinophilic chronic rhinosinusitis Auris Nasus Larynx (IF 1.7) Pub Date : 2023-08-11 Takeshi Tsuda, Masanobu Suzuki, Yukinori Kato, Masanori Kidoguchi, Takumi Kumai, Shigeharu Fujieda, Masafumi Sakashita
Chronic rhinosinusitis (CRS) is a persistent inflammatory disease of the nasal cavity and paranasal sinuses. Traditional classification is denoted by the presence (CRSwNP) or absence of nasal polyps (CRSsNP). Particularly, CRSwNP is distinguished by the presence of infiltrating cells and inflammatory markers in the nasal mucosa. Patients with CRSwNP in Western countries predominantly display a type
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Cochlear implantation for progressive hearing loss caused by an A8296G mutation in mitochondrial DNA Auris Nasus Larynx (IF 1.7) Pub Date : 2023-08-10 Toshihito Sahara, Akinori Kashio, Teru Kamogashira, Erika Ogata, Yusuke Akamatsu, Tatsuya Yamasoba
Mitochondrial DNA mutations such as A3243G or A1555G are widely reported to cause hearing loss, but few reports exist on the A8296G mutation, which can also cause hearing loss. This report presents the case of a patient with the A8296G mutation and severe bilateral sensorineural hearing loss (SNHL) that progressed over two decades. The patient had no history of diabetes, but did have a family history
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Tracheostomy in otorhinolaryngology education and training programs: A Japanese nationwide survey Auris Nasus Larynx (IF 1.7) Pub Date : 2023-08-08 Masaaki Higashino, Koichiro Saito, Kiyoaki Tsukahara, Masamitsu Hyodo, Hideki Hirabayashi, Ryo Kawata
Objective Surgical airway management is one of the most effective techniques for safe airway management. Within the training programs relating to knowledge and skills required by otorhinolaryngologists, tracheostomy and postoperative management are important items that must be fully understood by airway surgeons. We performed a nationwide survey to identify problems within tracheostomy and postoperative
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Enhanced recovery pathways for head and neck surgery with free tissue transfer reconstruction Auris Nasus Larynx (IF 1.7) Pub Date : 2023-08-07 Takayuki Imai, Yukinori Asada, Kazuto Matsuura
The enhanced recovery after surgery (ERAS) pathway is designed to facilitate recovery after surgery by packaging evidence-based protocols specific to each aspect of the perioperative period, including the preoperative, intraoperative, postoperative, and post-discharge periods. The ERAS pathway, which was originally developed for use with colonic resection, is now being expanded to include a variety
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Triple endoscopy and recurrent croup in children: A single aerodigestive center experience Auris Nasus Larynx (IF 1.7) Pub Date : 2023-08-06 Jennifer P. Vu, Deepak Jagannath, David R. Spielberg, Eric H. Chiou, Kathleen E. Hosek, Elton M. Lambert
Objective To determine the utility of triple endoscopy (combined direct laryngoscopy, bronchoscopy (DLB), flexible bronchoscopy with bronchoalveolar lavage (FB + BAL), and esophagogastroduodenoscopy (EGD)) in the diagnosis and management of patients with recurrent croup (RC), and to identify predictors of endoscopic findings Methods A retrospective chart review was performed of pediatric patients (age
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Endoscopic balloon dilatation in the management of paediatric-acquired subglottic stenosis in children Auris Nasus Larynx (IF 1.7) Pub Date : 2023-08-04 Lanye Hu, Ning He, Shan He, Yu Jiao
Objective To summarise our experience and the outcomes of endoscopic balloon dilatation (EBD) in the management of paediatric-acquired subglottic stenosis (SGS), and to further explore the influencing factors of successful EBD. Method A retrospective case series study was conducted involving 33 paediatric patients diagnosed with acquired SGS who underwent EBD as the primary treatment from January 2012
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Application of phosphorylcholine derivative as mucosal adjuvant enhancing mucosal immune responses in the upper respiratory tract Auris Nasus Larynx (IF 1.7) Pub Date : 2023-07-31 Tomohiro Jimura, Yuichi Kurono, Takashi Hirano, Masaki Kawabata, Masaru Yamashita
Objective A phosphorylcholine (PC)-derivative with high binding ability (PCDB) was intranasally administered to mice with ovalbumin (OVA), and immune responses were investigated to determine whether PCDB has antigenicity and adjuvanticity. Methods BALB/c mice were intranasally immunized with PCDB coupled with OVA, unbound PCDB plus OVA, cholera toxin (CT) plus OVA, OVA alone, and PCDB alone. Then,
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Long-term effects of second cochlear implantation with sequential bilateral cochlear implantation in Japanese children Auris Nasus Larynx (IF 1.7) Pub Date : 2023-07-24 Naoe Mori, Norio Yamamoto, Shinobu Yamaguchi, Kanako Kondo, Misaki Yoshizawa, Takayuki Okano, Juichi Ito, Koichi Omori
Objective This study aimed to longitudinally evaluate speech perception ability and sound-field thresholds with the first, second, or bilateral cochlear implants (CIs) and MAP parameters of second CI in children. Methods Eighteen children who underwent bilateral cochlear implantation at Kyoto University Hospital were included. We evaluated speech perception under quiet and noisy conditions using the
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Summary of Japanese clinical practice guidelines for head and neck cancer - 2022 update edited by the Japan society for head and neck cancer Auris Nasus Larynx (IF 1.7) Pub Date : 2023-07-21 Akihiro Homma, Mizuo Ando, Nobuhiro Hanai, Hiroyuki Harada, Yoshitaka Honma, Tomonori Kanda, Satoshi Kano, Daisuke Kawakita, Naomi Kiyota, Yoshiyuki Kizawa, Masahiro Nakagawa, Takenori Ogawa, Hirotaka Shinomiya, Takeshi Shinozaki, Motoyuki Suzuki, Tetsuya Tsuji, Koichi Yasuda, Sadamoto Zenda, Takeshi Kodaira, Tadaaki Kirita, Ken-ichi Nibu
The aim of the “Japanese Clinical Practice Guidelines for Head and Neck Cancer - 2022 Update” is to review the latest evidence regarding head and neck cancer and to present the current standard approaches for diagnosis and treatment. These evidence-based recommendations were created with the consensus of the Guideline Committee, which is composed of otorhinolaryngologists and head and neck surgeons
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Tumor localization is the important factor for recovery time of postoperative facial nerve paralysis in benign parotid surgery Auris Nasus Larynx (IF 1.7) Pub Date : 2023-07-21 Ichita Kinoshita, Ryo Kawata, Masaaki Higashino, Tetsuya Terada, Shin-Ichi Haginomori, Takeshi Tochizawa
Objective Facial nerve paralysis is the most problematic complication of surgery for parotid tumors. This study aimed to examine the progress of recovery from postoperative transient facial nerve paralysis (POFNP). Methods Participants were 203 patients who developed POFNP after benign parotid surgery. A Kaplan-Meier showed the progress of recovery from paralysis. Factors involved in recovery were
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A manual of Eustachian tube function tests–illustration of representative test results obtained from healthy subjects and typical disorders with suggestion of the appropriate test method of choice Auris Nasus Larynx (IF 1.7) Pub Date : 2023-07-05 Ryoukichi Ikeda, Shigeto Ohta, Satoshi Yoshioka, Shiori Endo, Kana Lee, Toshiaki Kikuchi, Haruo Yoshida, Akira Inagaki, Akihiro Kaneko, Hitome Kobayashi, Naohiro Yoshida, Takeshi Oshima, Kunihiro Mizuta, Masahiro Morita, Nobumasa Yamaguchi, Haruo Takahashi, Toshimitsu Kobayashi
In the 19th century, Politzer devised a method to measure passage of the Eustachian tube (ET) by pressurizing the nasopharyngeal cavity, which marked the beginning of the ET function test. Since then, various examination methods have been developed. While ET function testing is important, recent advancements in diagnostic imaging and treatments have renewed interest on its importance. In Japan, the
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Improved vocal quality and decreased vocal effort after botulinum toxin treatment for laryngeal dystonia Auris Nasus Larynx (IF 1.7) Pub Date : 2023-06-24 Jai-sen Leung, Andrés Rosenbaum, Jorge Holmberg, Pablo Villarroel, Carla Napolitano, Pedro I. Badía, Antonia Lagos-Villaseca
Objectives: Laryngeal dystonia (LD) is characterized by irregular and involuntary task-specific spasms of the intrinsic laryngeal muscles. There is no curative treatment for it, however, laryngeal botulinum neurotoxin injections (BoNT-I) are considered the standard of care therapy. This study aims to characterize the population of LD patients and to assess the results of laryngeal BoNT-I. Methods:
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Platinum resistance and sensitivity in recurrent/metastatic head and neck squamous cell carcinoma Auris Nasus Larynx (IF 1.7) Pub Date : 2023-06-17 Yuto Horichi, Hidetoshi Matsui, Yuta Yamamura, Shigemichi Iwae
Objective For patients with recurrent/metastatic head and neck squamous cell carcinoma (R/MHNSCC), platinum-free interval (PFI)-based differences in the effectiveness of rechallenge with platinum-based chemotherapy (PBCT) remain unknown. We aimed to evaluate the difference in platinum sensitivity based on PFI in R/MHNSCC. Methods We retrospectively examined 80 patients with R/MHNSCC who underwent PBCT
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Radiologic evaluation and clinical assessment of facial sinus in adults and children – computed tomography study Auris Nasus Larynx (IF 1.7) Pub Date : 2023-06-17 Tomasz Wojciechowski, Tymon Skadorwa, Matteo Fermi, Kazimierz Szopiński
Objective The facial sinus is a recess of the lateral retrotympanum located between the chorda tympani (ChT) and facial nerve (FN). Chronic otitis media with cholesteatoma often spreads from the pars flaccida to the facial sinus (FS). In stapedotomy, if an unfavorable ChT type is encountered, there is a need for removal of bone between the ChT and FN. The aim of the study was to assess FSs in adults
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Letter to the editor: COVID-19 findings revealed via otolaryngological examination: Findings of a Japan Otorhinolaryngologist Association questionnaire Auris Nasus Larynx (IF 1.7) Pub Date : 2023-06-13 Yurika Kimura
Abstract not available
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Simple lip reconstruction technique for middle-sized defects in lower lip cancer — Bilateral oblique mucosal V-Y advancement flap Auris Nasus Larynx (IF 1.7) Pub Date : 2023-06-12 Shunsuke Miyamoto, Takashi Matsuki, Taku Yamashita
There is no standardized technique for lip reconstruction because the structure and functions of the lip are diverse. We developed a new lip reconstructive approach using a bilateral oblique mucosal V-Y advancement flap. We present the case of a 76-year-old woman with severe dementia, referred to our institute for a tumor on her lower lip. She was diagnosed with lip squamous cell carcinoma (cT2N0M0)
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Characteristic findings in the human fetus vestibule: A human temporal bone study Auris Nasus Larynx (IF 1.7) Pub Date : 2023-06-10 Yohei Honkura, Yukio Katori, Ai Hirano-Kawamoto, Tetsuaki Kawase, Jose Francisco Rodríguez-Vázquez, Gen Murakami, Hiroshi Abe
Objective The “collapse,” a highly flexed, dented, or caved membrane between the endo- and peri-lymph of the saccule and utricle in adults, is considered as a morphological aspect of Ménière's syndrome. Likewise, when mesh-like tissues in the perilymphatic space are damaged or lost, the endothelium loses mechanical support and causes nerve irritation. However, these morphologies were not examined in
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Authors’ reply to: Comment on the article by Dr. Yuki Otsuka: COVID-19 Omicron variant-induced laryngitis Auris Nasus Larynx (IF 1.7) Pub Date : 2023-06-05 Yurika Kimura
Abstract not available
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A multi-institutional retrospective study of 340 cases of sinonasal malignant tumor Auris Nasus Larynx (IF 1.7) Pub Date : 2023-05-27 Takuya Tsuji, Ryo Asato, Shinpei Kada, Morimasa Kitamura, Hisanobu Tamaki, Masanobu Mizuta, Shinzo Tanaka, Yoshiki Watanabe, Ryusuke Hori, Tsuyoshi Kojima, Shogo Shinohara, Shinji Takebayashi, Toshiki Maetani, Hiroyuki Harada, Yoshiharu Kitani, Yohei Kumabe, Takashi Tsujimura, Keigo Honda, Kazuyuki Ichimaru, Koji Ushiro, Koichi Omori
Objective Sinonasal malignant tumors (SNMT) are relatively rare among head and neck malignant tumors. Most are squamous cell carcinomas, and malignant melanomas, olfactory neuroblastomas, adenoid cystic carcinomas, sarcomas, and others also occur. The most common primary site of nasal sinus squamous cell carcinoma is the maxillary sinus. In recent years, a decrease in incidence of maxillary sinus squamous
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Electrical promontory stimulation test using a portable peripheral nerve stimulator with an ear canal electrode Auris Nasus Larynx (IF 1.7) Pub Date : 2023-05-14 Michiko Kurasawa, Takeshi Nakamura, Akira Ganaha, Takahiro Nakashima, Tetsuya Tono
Objective An intact cochlear nerve is necessary for successful cochlear implantation (CI). Although the promontory stimulation test (PST) using a promontory stimulator (PS) and a transtympanic needle electrode is invasive, it is still commonly used to verify cochlear nerve function. PSs are currently unavailable because they are no longer manufactured; however, considering that PST continues to be
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Effects of vocal fold lesions on particle deposition in a mouth-throat model: A numerical study Auris Nasus Larynx (IF 1.7) Pub Date : 2023-05-08 Pengcheng Yu, Chao Xue, Jonah Rosenthal, Jack J. Jiang
Objective Dysphonia is very common worldwide and aerosol drug inhalation is an important treatment for patients with dysphonia. This study aimed to explore the effects of vocal fold (VF) lesions on the particle deposition pattern using computational modeling. Methods A realistic mouth-throat (MT) model of a healthy adult was constructed based on computed tomography images. Small and large vocal fold
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Comprehensive Genome profile testing in head and neck cancer Auris Nasus Larynx (IF 1.7) Pub Date : 2023-05-08 Masashi Kuroki, Ryota Iinuma, Hiroshi Okuda, Kosuke Terazawa, Hirofumi Shibata, Ken-ichi Mori, Toshimitsu Ohashi, Akitaka Makiyama, Manabu Futamura, Tatsuhiko Miyazaki, Yukio Horikawa, Takenori Ogawa
Objective Head and neck cancer (HNC) is a tumor occurring in various primary sites with limited chemotherapy options for its treatment. Recently, comprehensive genomic profiling (CGP) testing has become clinically widespread. In this study, we examined the utility of CGP in diagnosing and treating HNC. Methods This study included 29 patients with HNC who underwent CGP testing at the Gifu University
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Physical therapy for peripheral facial palsy: A systematic review and meta-analysis Auris Nasus Larynx (IF 1.7) Pub Date : 2023-05-04 Haruki Nakano, Takashi Fujiwara, Yasushi Tsujimoto, Naohito Morishima, Takashi Kasahara, Misato Ameya, Keita Tachibana, Shota Sanada, Saori Toufukuji, Naohito Hato
Objective This study aimed to reveal the efficacy of physical therapy for patients with peripheral facial palsy. Methods A literature search was conducted using PubMed, Ichushi-Web, and Cochrane Central Register of Controlled Trials. Published randomized controlled trials comparing the physical therapy versus placebo/non-treatment for peripheral facial palsy such as Bell's palsy, Ramsay Hunt syndrome