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Cancer mortality patterns in selected Northern and Southern African countries. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-11-24 Margherita Pizzato,Claudia Santucci,Fabio Parazzini,Eva Negri,Carlo La Vecchia
BACKGROUND Non-communicable diseases have been rapidly increasing in African countries. We provided updated cancer death patterns in selected African countries over the last two decades. METHODS We extracted official death certifications and population data from the WHO and the United Nations Population Division databases. We computed country- and sex-specific age-standardized mortality rates per 100 000
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Construction and validation of a nomogram prediction model for axillary lymph node metastasis of cT1 invasive breast cancer. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-11-21 Shuqi Wang,Dongmo Wang,Xin Wen,Xiangli Xu,Dongmei Liu,Jiawei Tian
OBJECTIVE Based on the ultrasonic characteristics of the breast mass and axillary lymph nodes as well as the clinicopathological information, a model was developed for predicting axillary lymph node metastasis in cT1 breast cancer, and relevant features associated with axillary lymph node metastasis were identified. METHODS Our retrospective study included 808 patients with cT1 invasive breast cancer
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Cancer worry at higher-risk sample of hereditary cancer in Spain. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-11-13 Gema Costa-Requena,Paula Richart-Aznar,Ángel Segura-Huerta
BACKGROUND Few studies have examined the prevalence of cancer worry in the general and at-risk population. The objective of this study was to describe the prevalence of cancer worry in a sample of individuals at increased risk of developing hereditary cancer, determine differences in cancer worry by socio-demographic characteristics and assess the relationship between cancer worry and psychological
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Meta-analysis of the prognostic value of serum carcinoembryonic antigen in patients with colorectal cancer liver metastases after hepatectomy. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-11-13 Chenzhao Yuan,Lumin Zeng,Hongxiang Duan,Benjamas Suksatit
OBJECTIVES Carcinoembryonic antigen (CEA) is a broad-spectrum tumor marker for differential diagnosis, monitoring, and response assessment of a variety of malignancies. This meta-analysis was aimed at evaluating whether serum CEA could predict the prognosis in patients with colorectal cancer liver metastasis (CRCLM) before and after liver resection (LR). METHODS PubMed, Embase, Cochrane, and Web of
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Association between sociodemographic and clinical features, health behaviors, and health literacy of patients with prostate cancer and prostate cancer prognostic stage. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-11-06 Raquel Braga,Natália Araújo,Adriana Costa,Catarina Lopes,Isa Silva,Rita Correia,Filipa Carneiro,Isaac Braga,Luis Pacheco-Figueiredo,Jorge Oliveira,Samantha Morais,Vítor Tedim Cruz,Susana Pereira,Nuno Lunet
Patient characteristics may influence access and acceptance of Prostate Specific Antigen test, and therefore, the timing of prostate cancer (PCa) diagnosis. A group of 361 patients from a cohort (n = 451) diagnosed with PCa in 2018-2020 at the Portuguese Institute of Oncology of Porto was evaluated before treatment, using a structured interview, the Medical Term Recognition Test, and the EORTC Quality
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The multicenter experience in the multidisciplinary Italian breast units: a review and update. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-11-06 Francesca Magnoni,Corrado Tinterri,Giovanni Corso,Giuseppe Curigliano,Maria Cristina Leonardi,Antonio Toesca,Nicola Rocco,Francesca Catalano,Beatrice Bianchi,Federica Lauria,Pietro Caldarella,Gianmatteo Pagani,Viviana Galimberti,Paolo Veronesi
A breast unit is a multidisciplinary center specialized in the management of women with breast diseases, including breast cancer (BC). It represents a care path, passing from screening activities to diagnostic investigations, from surgery to the definition of the therapeutic strategy, from psychophysical rehabilitation to long-term checks (follow-up), and up to genetic counseling. Since 2006, following
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Temporal trends in incidence and mortality of cervical cancer in China from 1990 to 2019 and predictions for 2034. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-11-06 Shuang Li,Min Huang,Yan Zhu,Hai Zeng,Fan Zhang
OBJECTIVE This study aimed to analyze long-term trends of cervical cancer (CC) burden in China based on the GBD 2019 data and provide information and data support for formulating corresponding policies to control CC. METHODS Incidence and mortality rate data of CC in China were described using GBD 2019 data. The Joinpoint regression analysis and age-period-cohort model were implemented to describe
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Epidemiological trend of lung cancer burden caused by residential radon exposure in China from 1990 to 2019. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-11-06 Chengzhi Wang,Lei Shi
OBJECTIVE This study employed time series data to assess long-term changes in the burden of lung cancer (LC) caused by residential radon exposure, an important environmental risk factor, so as to develop evidence-based strategies for future public health management. METHODS Based on the open data from the Global Burden of Disease (GBD 2019) database, we conducted an analysis of the residential radon
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Chronos, Kairos, and the environmental control against radon. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-11-06 Luca Bertolaccini,Monica Casiraghi,Lorenzo Spaggiari
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The association between histological subtypes and lymph node metastasis and prognosis in early esophageal cancer: a population-based study. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-11-06 Jun-Peng Lin,Xiao-Feng Chen,Hang Zhou,Feng-Nian Zhuang,Hao He,Wei-Jie Chen,Feng Wang,Shuo-Yan Liu
BACKGROUND There is still a lack of high-level clinical evidence and uniform conclusions on whether there are differences in lymph node metastasis (LNM) and prognosis between early esophageal adenocarcinoma (EAC) and squamous cell carcinoma (ESCC). METHODS Patients with surgically resected, histologically diagnosed, pT1 EAC or ESCC in the Surveillance, Epidemiology and End Results registries database
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Randomised clinical trial: efficacy and safety of H. pylori eradication treatment with and without Saccharomyces boulardii supplementation. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-11-06 Olga Sjomina,Inese Poļaka,Jekaterina Suhorukova,Reinis Vangravs,Sergejs Paršutins,Viktoria Knaze,Jin Young Park,Rolando Herrero,Raul Murillo,Mārcis Leja
BACKGROUND Standard triple therapy is commonly prescribed Helicobacter pylori eradication regimen in Europe. However, the world is witnessing declines in eradication success. It is crucial to find better treatment options. AIMS To evaluate efficacy, compliance and side effects of H. pylori eradication treatment by adding Saccharomyces boulardii. METHODS We conducted a randomized clinical trial within
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Mediterranean diet and colorectal adenomas: a systematic review and meta-analysis of observational studies. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-11-06 Saeede Jafari Nasab,Cain C T Clark,Mohammadhasan Entezari
Colorectal adenomas (CRAs) are epithelial lesions of the large bowel that can develop into colorectal cancer. Some studies have shown an inverse association of the Mediterranean diet (MED) with adenoma, but the extent of the association is equivocal. Owing to the lack of meta-analytical evidence in the literature, we sought to assess the association between MED and CRAs by conducting a systematic review
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The role of the purinergic ligand-gated ion channel 7 receptor in common digestive system cancers. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-11-06 Xin Wang,Qingqing Yu,Xue Bai,Xinyu Li,Yanli Sun,Xiaoxiang Peng,Ronglan Zhao
The incidence of digestive malignancies has increased in recent years, including colorectal cancer (CRC), hepatocellular carcinoma (HCC) and pancreatic cancer. Advanced stages of these cancers are prone to metastasis, which seriously reduce the standard of living of patients and lead to decline in the survival rate of patients. So far there are no good specific drugs to stop this phenomenon. It is
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Reinvestigating the Perceptions of Annual Skin Cancer Screening Scale: a suitable measure for older adults. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-10-09 Matt C Howard
OBJECTIVES The Perceptions of Annual Skin Cancer Screening Scale (PASCSS) explains significant variance in whether people undergo annual clinical skin cancer screening beyond other relevant predictors. When developing the PASCSS, the author only tested its psychometric properties and validity with participants representative of the general USA population, despite the particular relevance of annual
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Is phased implementation of HPV testing and triage with dual staining the way to transform organized cytology screening? Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-09-21 Jiří Sláma,Vladimír Dvořák,Markéta Trnková,Aleš Skřivánek,Karolína Hrabcová,Petra Ovesná,Martina Nováčková
OBJECTIVE The substantial material and legislative investments in establishing and maintaining cytological screening in the Czech Republic represent barriers to a direct transition to primary HPV screening. Therefore, the LIBUSE project was implemented to test the efficacy of phasing in HPV DNA testing as a co-test to cytology in routine screening of women >30 years of age. METHODS Women aged 30 to
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Impact of risk perception and disease cognition on the willingness to participate in screening for lung cancer in a high-risk population. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-09-21 Feng Rong,Rui Shi,Lili Hu,Daoyue Wang,Xiazhi Lv,Yong Zhao
OBJECTIVE Risk perception and disease cognition may influence the efficiency of lung cancer screening by affecting the participation rate. There is still some uncertainty regarding the association between risk perception and disease cognition and how they affect participation in lung cancer screening. Therefore, we explored the influence of risk perception and disease cognition on the willingness to
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Spatial mapping of colorectal cancer screening uptake and associated factors. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-09-11 Getachew A Dagne
OBJECTIVE Over the past decades, it has been understood that the availability of screening tests has contributed to a steady decline in incidence of colorectal cancer (CRC). However, it is also seen that there is a geographic disparity in the use of such tests across small areas. The aim of this study is to examine small-area level barrier factors that may impact CRC screening uptake and to delineate
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Resilience and its related factors among women with breast cancer. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-09-11 Hossein Ostadi-Sefidan,Farnaz Faroughi,Azita Fathnezhad-Kazemi
OBJECTIVES Breast cancer is the most challenging disease, and the level of resilience in patients determines their ability to cope with the arising stress. There is relatively limited information on the resilience of patients in clinical settings. Our study aims were to evaluate the extent of resilience and identify factors that predict resilience in women with breast cancer. PATIENTS AND METHODS A
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Association of radiotherapy for stage I-III breast cancer survivors and second primary malignant cancers: a population-based study. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-09-05 Jin Shi,Jian Liu,Guo Tian,Daojuan Li,Di Liang,Jun Wang,Yutong He
PURPOSE With life span extending, breast cancer survivors may face the possibility of developing second primary cancers (SPCs). The objective of this research is to investigate the risk factors, risk attribute to radiotherapy and the survivalship for SPCs. METHODS A total of 445 523 breast cancer patients were enrolled from Surveillance, Epidemiology, and End Results database in 2000-2018. The risk
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Vitamin B12 deficiency after total gastrectomy for gastric cancer, prevalence, and symptoms: a systematic review and meta-analysis. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-09-05 Mansour Bahardoust,Zahra Aghakhani,Safa Mousavi,Ghazaleh Donyadideh,Hassan Ziafati,Homan Alipour,Meisam Haghmoradi,Faranak Olamaeian,Ali Tayebi,Adnan Tizmaghz
PURPOSE Nutrient deficiency is one of the common complications in patients who undergo gastrectomy, especially those vitamins and minerals absorbed in the stomach or by substances in the gastric juice, such as vitamin B12. Hence, this systematic review and meta-analysis were conducted for the first time to investigate the prevalence of vitamin B12 deficiency and its symptoms in gastric cancer (GC)
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Serum uric acid and the risk of colorectal cancer: a meta-analysis. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-08-28 Wenqiang Liao,Yuxiang Wang,Wenpeng Zhang
BACKGROUND A meta-analysis was performed in this study to evaluate the association between serum uric acid and the risk of colorectal cancer (CRC). METHODS Relevant observational studies observing the relationship between uric acid and the incidence of CRC were obtained by the search of electronic databases, including Medline, Embase, Cochrane Library and Web of Science. A randomized-effects model
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Impact of interaction between interleukin-6 gene polymorphism and Helicobacter pylori infection on susceptibility to gastric cancer. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-08-28 Longyue Wang,Shuaishuai Xiao,Yiming Zheng,Zefeng Gao,Fan Fan
OBJECTIVE This study aimed to evaluate the association between four single nucleotide polymorphisms (SNPs) of the interleukin-6 (IL-6) gene and gastric cancer (GC), and impact of interaction between IL-6 SNPs and Helicobacter pylori (H. pylori) infection on susceptibility to GC. METHODS Logistic regression was used to test the relationships between four SNPs of IL-6 gene and GC susceptibility. A generalized
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Uterine cancer deaths certified as part unspecified: an unsolved issue. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-08-17 Giovanna Esposito,Claudia Santucci,Fabio Parazzini,Silvia Mignozzi,Matteo Malvezzi,Carlo La Vecchia,Eva Negri
OBJECTIVE A large percentage of uterine cancer deaths worldwide are not attributed to the cervix or corpus, but classified as uterus part 'unspecified'. We provided the trend for the proportion of uterine cancer deaths certified as 'unspecified' in selected countries. METHODS We derived the proportions of 'unspecified' uterine cancers for 20 selected high- and middle-income countries with reliable
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Comprehensive analysis of the clinical and prognostic significance of SFRP1 and PRKCB expression in non-small cell lung cancer: a retrospective analysis. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-07-25 GuoQiang Hu,Juan Du,Bin Wang,PengTao Song,ShunLin Liu
OBJECTIVES Secreted frizzled-related protein 1 (SFRP1) and protein kinase C-B (PRKCB) contribute to cancer progression and angiogenesis. This study intended to detect SFRP1 and PRKCB expression in non-small-cell lung cancer (NSCLC) patients and analyze its association with clinicopathological features. METHODS A total of 108 NSCLC patients who underwent surgical resection in our hospital between 2012
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Development of a nomogram for predicting survival in clinical T1N0M1 lung adenocarcinoma: a population-based study. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-07-19 Xuejing Lin,Weicheng Tian,Ni Sun,Ziyang Xia,Pei Ma
OBJECTIVE This study aimed to establish a prognostic model for clinical T1N0M1 (cT1N0M1) lung adenocarcinoma patients to evaluate the prognosis of patients in terms of overall survival (OS) rate and cancer-specific survival (CSS) rate. METHODS Data of patients with metastatic lung adenocarcinoma from 2010 to 2016 were collected from the Surveillance, Epidemiology and End Results database. Multivariate
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Timely assessment of 5-year relative survival for patients with thyroid cancer from Taizhou, eastern China: a period analysis. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-07-19 Jiajia Huang,Jun Cao,Luyao Zhang,Meiyu Fang,Yongran Cheng,Da-Lin Lu,Liangyou Wang,Tianhui Chen
BACKGROUND While timely assessment of long-term survival in thyroid cancer patients is critical for assessing early detection and screening programs for thyroid cancer, those data are sorely lacking in China. We aimed to timely and accurately assess the long-term survival of thyroid cancer patients in eastern China. METHODS Patients diagnosed with thyroid cancer during 2004-2018 from four cancer registries
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Trends in the incidence of thyroid cancer among US persons from 2000 to 2019. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-07-12 Juebo Yu
BACKGROUND The incidence of thyroid cancer is increasing by 3% annually; however, the analysis was restricted to the period from 1973 to 2013, which could be changed in incidence trends over time. This study is to analyze trends in thyroid cancer incidence based on demographic and tumor characteristics at diagnosis using recent database. METHODS We used the Surveillance, Epidemiology, and End Results
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Bacterial biomarkers: new aspects of colorectal tumors diagnosis: reality or fantasy. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-07-11 Tayebe Shahbazi,Bita Bakhshi,Mohammad Sadegh Fazeli,Elahe Derakhshan-Nezhadc
As one of the most common cancers, colorectal cancer (CRC) is considered as a significant leading cause of cancer-related deaths worldwide. Gut microbiota is part of a complex microbial-based ecosystem in the human body so that changes in the microbiota could lead to a variety of diseases. A growing number of studies have shown that bacteria are both individually and collectively involved in the progression
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The role of intermittent fasting and the ketogenic diet in cancer disease: can they replace the Mediterranean diet? Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-07-03 Aleyna Nur Küçük,Seda Çiftçi
The prevalence of cancer is rising globally, and it is the second leading cause of death. Nutrition has an important influence on the risk of developing cancer. Moreover, changes in the gut microbiota are connected to the risk of developing cancer and are critical for sustaining immunity. Various studies have shown that intermittent fasting, ketogenic diet, and the Mediterranean diet are effective
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Micrometastases in the sentinel node after neoadjuvant therapy. Is axillary dissection still required? Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-07-03 Rosa Di Micco,Sabrina K R Fontana,Oreste D Gentilini,Viviana Galimberti
The present review intends to discuss the controversies and strengths in clinically node-positive patients with axillary nodal status ypN i+ / mi after neoadjuvant chemotherapy. Over the past 20 years, a de-escalation approach toward axillary surgery has been observed in patients with breast cancer. The worldwide use of sentinel node biopsy in the upfront setting and after primary systemic therapy
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Non-melanoma skin cancer event rates in a formalized clinical trial setting: considerations for clinical trial design. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-07-03 Taja Lozar,Kyungmann Kim,Thomas C Havighurst,Gary S Wood,Jill M Kolesar,Howard H Bailey
BACKGROUND Here we report clinical risk factors and event rates for the development of new non-melanoma skin cancer (NMSC) in a randomized, double-blind, placebo-controlled trial of the irreversible ornithine decarboxylase (ODC) inhibitor, difluromethylornithine (DFMO), over a 3-5-year follow-up. METHODS 147 placebo patients (white; mean age 60.2 years; 60% male) were evaluated for event rates and
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CDH1 hypermethylation: a potential molecular pathway for invasiveness in glioblastoma. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-07-03 Daniel R Belut,Estela de O Lima,Marco A Zanini,Aline F Galvani,Fabiana B Furtado,Adriana C Ferrasi
Glioblastoma is the most aggressive central nervous system primary tumor. Prognosis is poor, mainly due to the malignant characteristics of the tumor, such as high cell proliferation and invasiveness. CDH1 hypermethylation is linked to the invasive potential in various cancer types, but its importance is still unknown in glioblastoma. In this context, the methylation status of CDH1 was analyzed using
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Mild renal impairment is associated with increased cardiovascular events and all-cause mortality following cancer diagnosis. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-07-03 Yonatan Moshkovits,Adam Goldman,Shmuel Tiosano,Alon Kaplan,Maia Kalstein,Gabriella Bayshtok,Shlomo Segev,Ehud Grossman,Amit Segev,Elad Maor
BACKGROUND The association between mildly decreased renal function and cardiovascular (CV) outcomes in cancer patients remains unestablished. AIMS We sought to explore this association in asymptomatic self-referred healthy adults. METHOD We followed 25, 274 adults, aged 40-79 years, who were screened in preventive healthcare settings. Participants were free of CV disease or cancer at baseline. The
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Modifications to the video-assisted thoracoscopic surgery technique reduce 1-year mortality and postoperative complications in intrathoracic tumors. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-07-03 Valeriy Makarov,Suriya Yessentayeva,Rabiga Kadyrbayeva,Rustem Irsaliev,Igor Novikov
OBJECTIVE The purpose of the study is to analyze the immediate outcomes and results of video-assisted thoracoscopic lobectomy and lung resection performed in the surgical department of the AOC between 2014 and 2018. METHODS For the period from 2014 to 2018, 118 patients with peripheral lung cancer were operated on in the surgical department of the AOC. The following operations were performed: lobectomy
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The burden and trend of liver metastases in Shanghai, China: a population-based study. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-07-03 Hui-Chao Zheng,Jing Zhou,Yi-Chen Chen,Ying Yu,Wei Dai,Yan Han,Xiao-Pan Li,Sun-Fang Jiang
BACKGROUND Studies on the epidemiology of liver metastases (LM)-related mortality are rare. we aimed to describe the burden and trend of liver metastases in Pudong of Shanghai, which could be beneficial to cancer prevention. METHODS We performed a retrospective population-based analysis of cancer mortality data with liver metastases in Shanghai Pudong from 2005 to 2021. Long-term trends in crude mortality
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Duration of human papillomavirus persistence and its relationship with recurrent cervical dysplasia. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-07-03 Giorgio Bogani,Francesco Sopracordevole,Andrea Ciavattini,Enrico Vizza,Paolo Vercellini,Andrea Giannini,Fabio Ghezzi,Giovanni Scambia,Francesco Raspagliesi,Violante Di Donato,
OBJECTIVE To evaluate how the duration of human papillomavirus (HPV) persistence influences the risk of developing recurrent high-grade cervical dysplasia (CIN2+). METHODS Data of patients with persistent HPV infection (at least at 6 months) after primary conization were extracted from a multi-institutional Italian database, retrospectively. Kaplan-Meier and Cox proportional hazards models were used
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The putative role of ferroptosis in gastric cancer: a review. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-06-16 Li Wang,Haibin Wang
Ferroptosis is a unique cell death modality triggered by iron-dependent lipid peroxidation, with cysteine metabolism and glutathione-dependent antioxidant defence responses as the primary triggering mechanisms. Ferroptosis is an independent tumour suppression mechanism and has been implicated in various disorders. In tumourigenesis, ferroptosis plays a dual role in promoting and inhibiting tumours
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A novel prognostic signature contributes to precision treatment in colon adenocarcinoma with KRAS mutation. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-06-12 Weiwei Dong,He Zhang,Qingyan Li,Na Guan,Chao Yun,Huixia Zhao,Fengyun Zhang,Zhiyan Zeng,Yanyan Hu,Qiuwen Li,Jingwen Yang,Zihuan Ma,Meiling Chen,Wenhua Xiao
BACKGROUND Approximately 40% of colon cancer harbor Kirsten rat sarcoma viral oncogene ( KRAS ) mutations, but the prognostic value of KRAS mutations in colon cancer is still controversial. METHODS We enrolled 412 colon adenocarcinoma (COAD) patients with KRAS mutations, 644 COAD patients with KRAS wild-type and 357 COAD patients lacking information on KRAS status from five independent cohorts. A random
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A call for standardized reporting of early-onset colorectal peritoneal metastases. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-06-12 Rebecca J Austin-Datta,Carlo La Vecchia,Thomas J George,Faheez Mohamed,Paolo Boffetta,Sean P Dineen,Daniel Q Huang,Thanh-Huyen T Vu,Tin C Nguyen,Jennifer B Permuth,Hung N Luu
BACKGROUND The incidence of colorectal cancer (CRC) in patients under 50 years of age, i.e., early-onset CRC, has increased in the past two decades. Colorectal peritoneal metastases (CPM) will develop in 10-30% of CRC patients. CPM traditionally had a dismal prognosis, but surgery and novel systemic treatments appear to increase survival. Determining potential age-associated risk and prognostic factors
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BIA-ALCL in patients with genetic predisposition for breast cancer: our experience and a review of the literature. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-06-07 Riccardo Carbonaro,Giuseppe Accardo,Luca Mazzocconi,Stefano Pileri,Enrico Derenzini,Paolo Veronesi,Pietro Caldarella,Francesca De Lorenzi
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is an emerging non-Hodgkin's lymphoma that occurs exclusively in patients with breast implants. The estimated risk of developing BIA-ALCL from exposure to breast implants is largely based on approximations about patients at risk. There is a growing body of evidence regarding the presence of specific germline mutations in patients developing
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Determinants and changes in adherence to the World Cancer Research Fund/American Institute for Cancer Research cancer-prevention recommendations over the past 25 years in Switzerland. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-06-07 Flurina Suter,Nena Karavasiloglou,Oliver Hämmig,Sabine Rohrmann,Giulia Pestoni
OBJECTIVES The World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) established 10 lifestyle recommendations for cancer prevention. The current study examines the proportion and changes over 25 years of adherence to these recommendations and their determinants in Switzerland. METHODS On the basis of six Swiss Health Surveys (1992-2017, N = 110 478), an index reflecting
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Controversies and strengths of robot-assisted mastectomy. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-06-07 Joo Heung Kim,Antonio Toesca,Giada Pozzi,Guglielmo Gazzetta,Emilia Marrazzo,Hyung Seok Park
Nipple-sparing mastectomy (NSM) is used to improve cosmetic outcomes while maintaining oncological safety in patients with early breast cancer; however, NSM requires a higher level of skill and workload than mastectomy and is associated with long, visible scars. Robotic surgical systems reduce surgeon workload and facilitate precise surgery. Considering the increasing support of robot-assisted NSM
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Investigating the relationship between breast and gynecological cancers and infertility and its treatments: a case-control study. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-05-22 Somayyeh Naghizadeh,Farnaz Faroughi,Mojgan Mirghafourvand
OBJECTIVE Due to the high prevalence of breast and gynecological cancers among women, it is crucial to identify the risk factors of these cancers. Thus, the present study aimed to evaluate the relationship between breast and gynecological cancers and infertility and its treatments in women suffering from these cancers. METHODS This case-control study was conducted with the participation of 400 people
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Reply to comment on 'postmastectomy breast reconstruction for women with hereditary gastric and breast cancer syndrome'. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-05-20 Francesca De Lorenzi,Mario Alessandri Bonetti,Francesco Borelli
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Molecular characteristics and prognosis of breast cancer patients with different level of HER2 positivity after adjuvant and neoadjuvant chemotherapy. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-05-20 Dilihumaer Tuluhong,Xinfang Li,Hongyu Gao,Yueyun Zhu,Qiurong Li,Shaohua Wang
PURPOSE HER2-low breast cancer (BC) has renewed interests of researchers worldwide. Here, we aimed to investigate the clinicopathological characteristics of patients with HER2-low, HER2-0 and HER2 ultra-low BC and make conclusion. METHODS We collected cases of patients who were diagnosed as BC at Jingling General hospital. Immunohistochemistry was used to redefine HER2 scores. Kaplan-Meier methods
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Interactive or tailored digital interventions to increase uptake in cervical, breast, and colorectal cancer screening to reduce health inequity: a systematic review Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-05-10 Afua Richardson-Parry, Mitchell Silva, Jose M. Valderas, Shaantanu Donde, Seth Woodruff, Joris van Vugt
Background and objectives Significant health inequities exist in screening uptake for certain types of cancer. The review question was to identify and describe interactive, tailored digital, computer, and web-based interventions to reduce health inequity in cancer screening and review the effectiveness of such interventions in increasing screening rates versus usual care. Methods We searched four
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An evaluation of the methodological quality of published guidelines for the surgical treatment of pleural mesothelioma Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-05-03 Luca Bertolaccini, Claudia Bardoni, Gabriele Maffeis, Shehab Mohamed, Elena Prisciandaro, Cristina Diotti, Monica Casiraghi, Francesco Petrella, Lorenzo Spaggiari
Background To benchmark their quality, a project was designed to analyze the methodology of previous guidelines and recommendations for malignant pleural mesothelioma projects. Methods A narrative literature search was conducted, and each guideline was evaluated using the Appraisal of Guidelines for Research and Evaluation (AGREE) II tool and rated on a seven-point scale for its many items and domains
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Screening approaches for cervical cancer in Mozambique in HIV positive and negative women Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-05-03 Alberto Sineque, Carlos Catalao, Susanna Ceffa, Ana Maria Fonseca, Fernanda Parruque, Giovanni Guidotti, Cacilda Massango, Carla Carrilho, Clara Bicho, Ricardina Rangeiro, Stefano Orlando, Maria Cristina Marazzi, Cesantina Lorenzoni, Fausto Ciccacci
Objective Cervical cancer (CC) is a global health issue, in Mozambique, 5300 new cases and 3800 deaths are reported each year. The WHO recommends the introduction of HPV molecular testing for CC screening, but Mozambique uses an approach based on visual inspection with acetic acid (VIA). This study aims to evaluate the feasibility of high-risk HPV (hrHPV) testing compared to actual approaches in Mozambique
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Presence of schistosome eggs in lymph node predict unfavorable prognosis in schistosomal colorectal cancer. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-05-03 Weiyu Pan,Jiaojiao Guo,Jiali Li,Jieakesu Su,Xiaolei Zhang,Jia Liu,Chen Xu,Yingyong Hou
OBJECTIVE The purpose of this study was to investigate the prognostic significance of schistosome eggs' location in schistosomal colorectal cancer (SCRC). METHODS 172 cases of SCRC were retrospectively analyzed. Patient clinicopathological parameters and survival rates were analyzed. RESULTS There were 102 males and 70 females, the median age was 71 years (range, 44-91). All patients were followed
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An evaluation of the methodological quality of published guidelines for the surgical treatment of pleural mesothelioma. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-03-03 Luca Bertolaccini,Claudia Bardoni,Gabriele Maffeis,Shehab Mohamed,Elena Prisciandaro,Cristina Diotti,Monica Casiraghi,Francesco Petrella,Lorenzo Spaggiari
BACKGROUND To benchmark their quality, a project was designed to analyze the methodology of previous guidelines and recommendations for malignant pleural mesothelioma projects. METHODS A narrative literature search was conducted, and each guideline was evaluated using the Appraisal of Guidelines for Research and Evaluation (AGREE) II tool and rated on a seven-point scale for its many items and domains
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Immune plasticity in pregnancy-associated breast cancer tumorigenesis Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-04-10 Konstantinos Venetis, Elham Sajjadi, Fedro A. Peccatori, Elena Guerini-Rocco, Nicola Fusco
Pregnancy-associated breast cancer (PrBC) is a rare tumor that requires complex management. The coexistence of cancer and pregnancy involves several proliferative, invasive, and immune tolerance mechanisms that are shared between the two conditions. In normal pregnancy, successful fetal development is achieved through suppression of the maternal immune response toward the fetus. Similar immunosuppressive
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Cancer mortality predictions for 2023 in Latin America with focus on stomach cancer Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-04-10 Claudia Santucci, Matteo Malvezzi, Fabio Levi, Maria Constanza Camargo, Paolo Boffetta, Carlo La Vecchia, Eva Negri
Objective We estimated cancer mortality statistics for the current year in seven major Latin American countries. Methods We retrieved official death certification data and population figures from the WHO and the United Nations databases for the 1970–2020 calendar period. We considered mortality from all neoplasms combined and for 10 major cancer sites. We estimated the number of deaths and age-standardized
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Functional variant rs10175368 which affects the expression of CYP1B1 plays a protective role against breast cancer in a Chinese Han population Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-04-10 Jiarui Liu, Lijia Zhang, Mingwen Tang, Xinyu Chen, Caiyun Yang, Yong Li, Jin Feng, Yan Deng, Xin Wang, Yi Zhang
Objective Cytochrome P450 1B1 (CYP1B1) genetic variants are relevant in the pathogenesis of breast cancer. Exploring the relationships between CYP1B1 functional variants and breast cancer could improve our understanding of breast cancer molecular pathophysiology. Methods This is a two-stage hospital-based case–control study of a Chinese Han population. Genotyping was performed to identify candidate
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Seaweed consumption and the risk of prostate cancer: the Miyagi cohort study Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-04-10 Koichi Matsumoto, Yumi Sugawara, Toshimasa Sone, Seiki Kanemura, Akira Fukao, Ichiro Tsuji
Some laboratory studies have shown that fucoidan, which is contained in seaweed extract, has inhibitory effects on the invasion and angiogenesis of tumor cells; however, the association between seaweed consumption and prostate cancer incidence remains unclear. The purpose of the present study was to examine the association between seaweed consumption and the risk of prostate cancer incidence in the
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Hodgkin lymphoma in Brazil: trends in incidence and mortality over 4 decades Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-04-10 Talita Maira Bueno da Silveira, Diego Rodrigues Mendonça e Silva, Gisele Aparecida Fernandes, Thaina Lucio da Silva, Maria Paula Curado
Background In Brazil, there is lack of studies on the incidence and mortality of this malignancy. The aim of this study was to describe the profile of HL in Brazil for incidence, mortality and trends. Methods Data on incidence in Brazil were collected from Population-Based Cancer Registries (1988–2017) and mortality for 1979–2019. Age-standardized incidence and mortality rates were calculated. Average
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Computational pathology to improve biomarker testing in breast cancer: how close are we? Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-04-10 Elham Sajjadi, Chiara Frascarelli, Konstantinos Venetis, Giuseppina Bonizzi, Mariia Ivanova, Gianluca Vago, Elena Guerini-Rocco, Nicola Fusco
The recent advancements in breast cancer precision medicine have highlighted the urgency for the precise and reproducible characterization of clinically actionable biomarkers. Despite numerous standardization efforts, biomarker testing by conventional methodologies is challenged by several issues such as high inter-observer variabilities, the spatial heterogeneity of biomarkers expression, and technological
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Immune plasticity in pregnancy-associated breast cancer tumorigenesis. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-04-10 Konstantinos Venetis,Elham Sajjadi,Fedro A Peccatori,Elena Guerini-Rocco,Nicola Fusco
Pregnancy-associated breast cancer (PrBC) is a rare tumor that requires complex management. The coexistence of cancer and pregnancy involves several proliferative, invasive, and immune tolerance mechanisms that are shared between the two conditions. In normal pregnancy, successful fetal development is achieved through suppression of the maternal immune response toward the fetus. Similar immunosuppressive
-
Computational pathology to improve biomarker testing in breast cancer: how close are we? Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-04-10 Elham Sajjadi,Chiara Frascarelli,Konstantinos Venetis,Giuseppina Bonizzi,Mariia Ivanova,Gianluca Vago,Elena Guerini-Rocco,Nicola Fusco
The recent advancements in breast cancer precision medicine have highlighted the urgency for the precise and reproducible characterization of clinically actionable biomarkers. Despite numerous standardization efforts, biomarker testing by conventional methodologies is challenged by several issues such as high inter-observer variabilities, the spatial heterogeneity of biomarkers expression, and technological
-
Cancer mortality predictions for 2023 in Latin America with focus on stomach cancer. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-04-10 Claudia Santucci,Matteo Malvezzi,Fabio Levi,Maria Constanza Camargo,Paolo Boffetta,Carlo La Vecchia,Eva Negri
OBJECTIVE We estimated cancer mortality statistics for the current year in seven major Latin American countries. METHODS We retrieved official death certification data and population figures from the WHO and the United Nations databases for the 1970-2020 calendar period. We considered mortality from all neoplasms combined and for 10 major cancer sites. We estimated the number of deaths and age-standardized
-
Functional variant rs10175368 which affects the expression of CYP1B1 plays a protective role against breast cancer in a Chinese Han population. Eur. J. Cancer Prev. (IF 2.4) Pub Date : 2023-04-10 Jiarui Liu,Lijia Zhang,Mingwen Tang,Xinyu Chen,Caiyun Yang,Yong Li,Jin Feng,Yan Deng,Xin Wang,Yi Zhang
OBJECTIVE Cytochrome P450 1B1 ( CYP1B1 ) genetic variants are relevant in the pathogenesis of breast cancer. Exploring the relationships between CYP1B1 functional variants and breast cancer could improve our understanding of breast cancer molecular pathophysiology. METHODS This is a two-stage hospital-based case-control study of a Chinese Han population. Genotyping was performed to identify candidate