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Intraoperative and Immediate Postoperative Transfusion: Clinical-Hematological Profile of Transfunded Patients in a University Hospital Transfus. Clin. Biol. (IF 1.7) Pub Date : 2024-03-09 Lorena dos Santos Goiabeira, Sara Silva Meireles, Allan Santos Silva Leocadio, Heitor Medeiros, Fernanda Cunha Soares, Wallace Andrino da Silva
The transfusion practice by surgery blood reserve, varied among services, must be performed through the rational and restrictive use of blood components because it is a scarce and expensive resource for health care services. Analyze the use of blood products for surgery blood reserve by means of the study of the clinical-hematological profile of patients submitted to intraoperative and immediate postoperative
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Study of the antigenic characteristics of red blood cells units and their sickle cell disease recipients and the G6PD activity of transfused red blood cells units Transfus. Clin. Biol. (IF 1.7) Pub Date : 2024-03-09 Morgane Le Gallo, Stéphane Moutereau, Mélanie Gentil, France Pirenne
La transfusion occupe une place centrale au cours de la drépanocytose. La compatibilité des groupes sanguins des concentrés de globules rouges (CGR) avec ceux du patient est essentielle pour prévenir l'allo-immunisation. La concordance des CGR de donneurs d’origine africaine est la meilleure avec les patients drépanocytaires. Cependant, ces CGR peuvent présenter des caractéristiques altérant leur conservation
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How we forecast tomorrow’s hemovigilance Transfus. Clin. Biol. (IF 1.7) Pub Date : 2024-03-07 Erica M Wood, Barbee I Whitaker, Mary Townsend, Shruthi Narayan
The field of haemovigilance continues to develop, building on more than forty years of international experience. This review considers the current scope and activities of haemovigilance around the world and explores aspects of preparation for the advent of new blood products and alternative therapies to transfusion; new tools for data acquisition (including patient- and donor-reported outcomes, and
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Expression of microRNAs during apheresis platelet storage up to day 14 in a blood bank in China Transfus. Clin. Biol. (IF 1.7) Pub Date : 2024-02-07 Jie Shi, Anqi Xu, Jun Ai, Jin Chen, Ying Luo
Storage affects platelet microRNAs (miRNAs); discussing miRNA expression differences in apheresis platelets after varied storage periods is important for developing platelet quality measurement tools and identifying platelet storage lesion biomarkers. To our knowledge, the difference of MicroRNA expression profile in up to 14-day storage apheresis platelets has less relevant reports. MiRNA expression
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What are the new challenges facing blood transfusion? Transfus. Clin. Biol. (IF 1.7) Pub Date : 2024-01-30 Olivier Garraud, Miquel Lozano, Tomislav Vuk
Abstract not available
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Acknowledging our reviewers 2023 Transfus. Clin. Biol. (IF 1.7) Pub Date : 2024-01-30
Abstract not available
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MOLECULAR FREQUENCY OF HUMAN GEMYCIRCULARVIRUS (GCYV) DNA AMONG BLOOD DONORS FROM THE BRAZILIAN AMAZON Transfus. Clin. Biol. (IF 1.7) Pub Date : 2024-01-26 Marlon Breno Zampieri Lima, Thuany Giovana Pereira Daniel, Hellen Tayaná Oliveira Bitencourt, Luiz Carlos Junior Alcantara, Rodrigo Haddad, Simone Kashima, Maria Carolina Elias, Marta Giovanetti, Sandra Coccuzzo Sampaio, Svetoslav Nanev Slavov
It has been recently reported that genetic material of human gemycircularviruses (GCYV) can be detected by metagenomics in clinical samples. However, the potential clinical impact of these viruses is still unknown. In this study, we evaluated the molecular prevalence of GCYV DNA among asymptomatic blood donors from the city of Macapa, Amapa State, Brazilian Amazon. During 2015, plasma samples obtained
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L-carnitine contributes to enhancement of viability and quality of platelet concentrates through changing the apoptotic and anti-apoptotic associated microRNAs Transfus. Clin. Biol. (IF 1.7) Pub Date : 2024-01-22 Mozhgan Norouzi, Seyed Alireza Mesbah-Namin, Zohreh Sharifi, Mohammad Reza Deyhim
Background Micro RNAs are known as the main regulator of messenger RNA translation in platelets and have a vital role in process of apoptosis during platelet storage. Our pervious study revealed that the expression of miR-145 and miR-326 changed significantly in platelets under maintenance conditions. This study aimed to evaluate the effect of L-carnitine (LC) as an additive to augment platelet quality
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Manual red cell exchange (RBCXm) in acute sickle cell crisis: A cost effective modality in resource limited settings Transfus. Clin. Biol. (IF 1.7) Pub Date : 2024-01-18 Yashaswi Dhiman, Basanta Khatiwada, Kunal Das, Manish Raturi, Dushyant Singh Gaur
This short communication highlights the significance of manual red blood cell exchange (RBCXm) procedure which is an emergency procedure for patients of sickle cell disease (SCD) in sickle cell crisis . To the best of our knowledge there is no standardised technique for performing RBCXm meanwhile, an automated method using an apheresis machine is either unavailable or is unaffordable. As a result,
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Prevalence of the Hematopoietic Rare Genetic Diseases in Turkey: A Retrospective Study Transfus. Clin. Biol. (IF 1.7) Pub Date : 2024-01-11 Mahir ÜLGÜ, Serkan YILMAZ, Duygu ÖZTAŞ, Bayram GÖKTAŞ, Abdullah AKÜNAL
Background Rare genetic diseases are an important global public health problem. At present there are defined approximately 8120 genetic diseases in 15,465 epidemiological datasets and 70% of them start in childhood. Hematopoiesis is the production of all cellular components of blood and continues throughout life. Objective This study aims to present prevalence of hematopoietic rare genetic diseases
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The role and importance of epidemiology in transfusion medicine Transfus. Clin. Biol. (IF 1.7) Pub Date : 2024-01-11 Constantina Politis, Tomislav Vuk, Clive Richardson, Lida Politi, Olivier Garraud
Transfusion therapy is an indispensable form of treatment, and an important element of the public health system. Due to its origin, blood’s clinical use is associated with various risks that may cause adverse reactions and events. Progress in quality and safety of blood components has eliminated numerous risks, especially those of infectious origin. However, some risks cannot be predicted, while others
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S.O.S. – Save Our Supplies: Understanding reasons to tackle the challenge of wasted returned blood products Transfus. Clin. Biol. (IF 1.7) Pub Date : 2024-01-10 Deep Madkaiker, Karitk Iyer, , Deepika Chenna, Ganesh Mohan, Shamee Shastry
Objectives To evaluate the return of blood components across different hospital areas, reasons for the same and suggest preventive strategies which might reduce out of controlled temperature storage (CTS) blood logistics and wastage. Material and methods A retrospective audit was carried out in the department of transfusion medicine from January 2019 to December 2022. Data related to returned blood
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Is prophylactic intraoperative transfusion needed in unilateral total knee arthroplasty? Comparison of hematologic data and postoperative transfusion rate between a prophylactic allogenic or autologous transfusion group with a no-transfusion group: A preliminary retrospective cohort study Transfus. Clin. Biol. (IF 1.7) Pub Date : 2024-01-10 Hee Jin Seon, Jimin Lee, Seo Kyeong Choi, Jae Ho Lee
Objectives To determine whether prophylactic intra-operative allogenic or autologous transfusion could prevent postoperative anemia and additional transfusion comparing to the control group without receiving any prophylactic intervention in unilateral total knee arthroplasty. Materials and methods This study included 711 patients who underwent unilateral TKA. They were divided into four groups: allogeneic
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Blood Transfusion Knowledge Levels of Nurses in İzmir Atatürk Training and Research Hospital, Turkey Transfus. Clin. Biol. (IF 1.7) Pub Date : 2024-01-08 Berrin Uzun, Vahide Yılmaz, Selvinaz Göklü, Ufuk Şahbaz, Hayri Güvel
Despite their use in life-saving treatment, blood and blood products can cause life-threatening complications. To administer blood transfusion safely, national guidelines and protocols should be consulted in healthcare organizations. In Türkiye, there are guides and regulations published by the Ministry of Health. With the definition of hemovigilance in the regulations; training in clinical use of
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Corrigendum du résumé «P-119 Phénotypage étendu aux systèmes de groupes sanguins rhésus, KIDD, DUFFY, KELL, MNSS, LEWIS, LUTHERAN, P des donneurs de sang de groupe sanguin O rhésus positif au centre national de transfusion sanguine du Sénégal» [Transfusion Clinique et Biologique 30(Supplement 1) (2023) S106-S107] Transfus. Clin. Biol. (IF 1.7) Pub Date : 2024-01-06 Harouna Ousmane Sow, Macoura Gadji, Oumar Atoumane Kane, Alioune Badara Senghor, Tandakha Ndiaye Dièye
Abstract not available
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Corrigendum du résumé «P-061 Quantification des anticorps IgM et IgG anti SARS-COV-2 chez les étudiants de l’Université Cheikh Anta Diop de Dakar» [Transfusion Clinique et Biologique 30(Supplement 1) (2023) S84] Transfus. Clin. Biol. (IF 1.7) Pub Date : 2024-01-05 Harouna Ousmane Sow, Macoura Gadji, Mamadou Woury Diallo, Oumar Atoumane Kane, Khadidiatou Kébé, Alioune Badara Senghor
Abstract not available
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Unmet needs in β-thalassemia and the evolving treatment landscape Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-12-20 Ryan Njeim, Bilal Naouss, Rayan Bou-Fakhredin, Antoine Haddad, Ali Taher
β-thalassemias are genetic disorders causing an imbalance in hemoglobin production, leading to varying degrees of anemia, with two clinical phenotypes: transfusion-dependent thalassemia (TDT) and non-transfusion-dependent thalassemia (NTDT). Red blood cell transfusions and iron chelation therapy are the conventional treatment options for the management of β-thalassemia. Currently available conventional
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Evaluating patient blood management practices using PBM metrics in a tertiary care center Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-12-16 Ashna George, Shamee Shastry, Ganesh Mohan, Sushma Belurkar
Background PBM metrics play a crucial role in assessing and monitoring the effectiveness of PBM programs in healthcare settings. The present study aimed to assess the indicators to achieve effective enforcement of PBM at a tertiary care referral hospital. Subjects and Method A prospective observational study was conducted on patients admitted for elective surgery at a tertiary care referral centre
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The first isoimmunized pregnancy Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-12-13 Jon F. Watchko
Abstract not available
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Presurgical circulating platelet-derived microparticles level as a risk factor of blood transfusion in patients with valve heart disease undergoing cardiac surgery Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-11-27 Mehrnaz Abdolalian, Elham Khalaf-Adeli, Fatemeh Yari, Saeid Hosseini, Pardis kiaeefar
Background Cell-derived microparticles (MPs) are membrane vesicles that have emerged as a potential biomarker for various diseases and their clinical complications. This study investigates the role of MPs as a risk factor for blood transfusion in patients with valve heart disease undergoing cardiac surgery. Methods Forty adult patients undergoing heart valve surgery with cardiopulmonary bypass (CPB)
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Effect of vibration of the vortex mixer on the red blood cells Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-11-24 Chuang Xiang, Liang Wang
Purposes Red blood cells (RBCs) are often subject to vibration during processing, transfusion, and transport. Further research is necessary to understand the effects of vibration on human RBCs and to reduce experimental deviations caused by device vibration. Methods Flow cytometry was used in this study to observe the cytokine expression of IgG and IgA and deformation of human red blood cells affected
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Application of anti-D immunoglobulin in D-negative pregnant women in China Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-11-23 Lihui Fu, Chunya Ma, Yang Yu
This article summarizes the current situation of anti-D immunoglobulin (anti-D-Ig) use in RhD-negative pregnant women at home and abroad. The article describes the concept, research and development history, and domestic and foreign applications of anti-D-Ig and points out that anti-D-Ig has not been widely used in China, mainly due to reasons such as unavailability in the domestic market and non-standard
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Therapeutic Leukocytapheresis to relieve priapism due to leukostasis in CML patients: Our experience in a tertiary care centre Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-11-08 Suhasini Sil, Aswin K Mohan, Gita Negi, Pradip Banerjee, Daljit Kaur, Ankur Mittal, Ashish Jain
Hyperleukocytosis in leukemic patients may cause tumour lysis syndrome, disseminated intravascular coagulopathy, and leukostasis, resulting in decreased tissue perfusion and increasing the risk of mortality. Since the myeloid blasts are larger than lymphoid blasts and are less deformable, complications of leukostasis are seen more frequently in myeloid leukemia. Priapism is a less common complication
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Implementation of Indian National plasma policy at blood bank of a tertiary care hospital: A step towards strengthening of blood transfusion services Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-10-20 Naveen Bansal, Kajal Khajuria, Rajbir Kaur Cheema, Ashish Sharma, Baltaran Singh Bajwa
Introduction The World Health Organization has advocated that every country should make its own policy for ensuring safe and adequate supply of plasma derived medicinal products through mobilization and usage of locally collected plasma. The National Plasma Policy (NPP) of India was published in 2014 with a dual objective to achieve self sufficiency in the production of plasma derived medicinal products
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Allelic frequency variation of ACKR1 in three Algerian populations: Zenata, Reguibat, and Oran Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-10-20 Leila Adda Neggaz, Tahria Deba, Asmahan Bekada, Djabaria Naima Meroufel Sebaa, Sounnia Mediene Benchekor, Soraya Benhamamouch
Introduction The discovery of the Duffy antigen is of great significance, given its essential role in immune response and various physiological processes. Genetic mutations in the Duffy gene not only affect antigen expression but also result in different antigen types. This underscores the importance of genetic characterization for clinical studies and exploring genetic diversity within the population
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Molecular analysis and transfusion management in a rare case of cis-AB blood group: A report from India Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-10-05 Suvro Sankha Datta, Mercy Rophina, Vinod Scaria
Molecular characterization of a rare cis-AB blood group has not been done in the Indian subcontinent. Herein, we report a case of A2B3 blood group in an Indian patient which was subsequently confirmed to be a case of cis-AB phenotype. Blood grouping was performed by the column agglutination technique (CAT), conventional tube technique (CTT) and subsequently, whole exome sequencing for molecular analysis
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The European health data space proposal: An opportunity for improved blood donor protection and transfusion recipient care Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-09-26 Pierre Tiberghien, Bernardo Rodrigues, Marjolaine Jacques, Peter O'Leary, Dragoslav Domanović
Abstract not available
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Need for standardization of technical manpower norms for Indian blood centres Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-09-20 Naveen Bansal, Gulshan Paul Saluja, Manish Raturi
Abstract not available
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Detection of red cell alloantibody prior to overflow phenomenon in a case of warm AIHA secondary to Chronic Lymphocytic Leukemia and Myasthenia Gravis: A case report Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-09-07 Davood Bava, Vasanth Asirvatham, Saptarshi Mandal, Amit Kumar Rohila, Siddharth Mittal
Introduction Defects in the lymphoid system have been linked to immune dysregulation, which might explain why lymphoid neoplasms and immunological disorders tend to occur concurrently. Chronic Lymphocytic Leukemia (CLL), characterised by the accumulation of dysfunctional lymphocytes, is associated with autoimmune cytopenias such as autoimmune haemolytic anaemia (AIHA). Detection of underlying alloantibody
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Application of a simplified PCR-SSP method to detect A4GALT*01 and A4GALT*02 typing among Thai blood donors Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-09-04 Pattaranit Amphonritthisak, Oytip Nathalang, Nipapan Leetrakool, Supattra Mitundee, Kamphon Intharanut
Objectives An intronic A4GALT single nucleotide variant, rs5751348:G>T, P2 or A4GALT*02 allele has a lower level of the enzyme-encoding A4GALT transcripts than the P1 individuals. Here, we first develop and validate a simple inhouse PCR-SSP method to detect A4GALT*01 and A4GALT*02 alleles, and second, apply this method to compare the allele frequencies between Thai and other populations. Material and
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Epidemiological characteristics and risk factors of syphilis among blood donors in Huzhou Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-08-20 Fei Jingxian, Wang Yun, Wang Le, Lv Ke, Chen Yizhu, Sun Quan, Wang Feng
Objective To investigate the epidemiological characteristics and risk factors for syphilis in Huzhou City, and to provide data to support the design of more effective health counselling and screening measures for blood donors. Methods A retrospective study was conducted to analyse the demographic characteristics and seropositivity of syphilis among blood donors from 2019 to 2021. The differences in
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Association of blood donor characteristics with hemoglobin content in leukoreduced packed red blood cells Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-08-19 Arpita Parmar, Paramjit Kaur, Tanvi Sood, Ravneet Kaur, Kshitija Mittal, Gagandeep Kaur, Vivek Muraleedharan, Noorul Aashiqeen
Background and Objectives A complex relationship exists between donor characteristics and red blood cell quality which remains partly explored. The present study aimed to determine the correlation of donor characteristics with the hemoglobin (Hb) content of leukoreduced packed red blood cells (PRBC). Materials and methods This prospective cross-sectional study was conducted on 100 blood donors. A pre-donation
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The Role of Artificial Intelligence in Optimizing the Donation Process and Predicting Blood Thresholds Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-08-18 Manish Raturi, Yashaswi Dhiman, Basanta Khatiwada, Dushyant Singh Gaur, Bhawana Adhikari, Poonam Rawat
Abstract not available
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Blood inventory management strategies to ensure adequacy of packed red blood cell stock Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-08-09 Naveen Bansal, Yashik Bansal, Charu Singh, Ashish Gulia
Abstract not available
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Reply to «Letter to the editor: Blood inventory management strategies to ensure adequacy of packed red blood cell stock» by Naveen Bansal et al. Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-08-07 Corentin Streel, Marie Pouplard, François Laporte, Olivier Bertrand, Urszula Luyten, Christine Pirlet, Youssra Khaouch, Véronique Deneys
Abstract not available
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The effect of thrombocytapheresis on hemogram and biochemistry parameters in patients with essential thrombocytemia Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-08-07 Ahmet Kaya, İrfan Kuku, Mehmet Ali Erkurt, Emin Kaya, İlhami Berber, Soykan Biçim, Emine Hidayet, Salih Cırık, Süleyman Arslan, Fatma Hilal Yagin, Ahmet Sarıcı
Background Essential thrombocythemia is one of the chronic myeloproliferative neoplasms characterized by clonal proliferation of myeloid cells with variable morphological maturation and hematopoietic activity. It is characterized by excessive clonal platelet production with a tendency to thrombosis and bleeding. Thrombocytapheresıs is the removal of platelets by apheresis techniques. Thrombocytapheresıs
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The impact of pre-donation viral markers screening of new blood donors on blood safety Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-08-06 Shirin Ferdowsi, Mahtab Maghsudlu, Ali A. Pourfathollah, Sedigheh Amini-Kafiabad, Mohammad Saied Karimian, Parisa Rahimzadeh, Pejman Salehifar
Background The risk of transfusion-transmissible infections (TTIs) remains a concern in transfusion medicine. Since the rate of infection among first-time blood donors is higher than repeated donors, strategies to enhance blood safety can focus on new donors. The aim of the study was to investigate the effect of pre-donation viral screening of new donors on blood safety. Methods and materials The pre-donation
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O-negative blood shortage management in a university hospital: Impact of transfusing RhD-positive red blood cells to RhD-negative patients Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-07-13 Urszula Luyten, Sarah Peeraer, Christine Pirlet, Youssra Khaouch, Corentin Streel, Véronique Deneys
Background Shortages of O-negative red blood cells are becoming increasingly common, forcing hospitals’ blood transfusion services to find solutions to conserve this blood group for patients who need it most. The present study aimed to retrospectively evaluate the practice of transfusing selected RhD-negative patients with RhD-positive red blood cells and to assess the impact of this measure on patients
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There is an urgent need to adopt a pull-flow logic for the supply of RBCs to meet patients’ needs: A single center study Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-07-13 Corentin Streel, Marie Pouplard, François Laporte, Olivier Bertrand, Urszula Luyten, Christine Pirlet, Youssra Khaouch, Véronique Deneys
Background Despite major demographic changes, several decisions and initiatives, among which Patient Blood Management, have led to a significant reduction in the transfusion of packed red blood cells (RBCs) in Belgium, as it has been observed in many countries. Unfortunately, not all blood groups were proportionately impacted and shortage in O D-negative RBCs is regularly or chronically observed. The
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Locally acquired malaria: An impending crisis for the United States blood supply? Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-07-06 Jeremy W. Jacobs, Garrett S. Booth, Brian D. Adkins
Abstract not available
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Serological and molecular analysis of the B(A) subtype in China—A systematic review Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-07-04 Jiang Wang, Yuxin Wang, Jinzhe Tan, Bin Tan
Objective To study the serological and molecular biological characteristics of the B(A) subtype and its geographical distribution in China through case discussion and systematic review. Methods A case of the B(A)02 subtype previously found in our laboratory was retrospectively analysed. The distribution characteristics and specific serological and genotypic characteristics of the B(A) subtype in China
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Education in blood transfusion: Adequacy of the content in the Kenyan undergraduate curricula and medical doctor’s perspectives and perceptions Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-06-29 Japheth C. Kipkulei, Richard B.O. Okero, Geoffrey K. Maiyoh
Background Although blood transfusion (BT) service is important in modern health care, blood is scarce, costly, and without risks. Medical education should therefore play a role in equipping medical doctors with the necessary BT knowledge, skills, and attitudes for optimal utilization of blood. This study aimed at determining the adequacy of curriculum content of Kenyan medical schools and the clinicians’
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Considering the impact of climate change and viral hemorrhagic fevers on the safety of the blood supply Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-06-29 Jeremy W. Jacobs, Garrett S. Booth, Laura D. Stephens, Jennifer S. Woo, Brian D. Adkins
Abstract not available
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Frequency of the ‘Asia type’ DEL with weak D phenotype in chinese Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-06-27 Jue Hou, Jian Li, Yu Xia, Xuemei Zhang, Jianying Yang, Meng Li, Ying Zhou
Background DEL individuals account for 9–30% of serological RhD negative population in east Asia and majority of them carrying the RHD*DEL1 allele are referred to as ‘Asia type’ DEL individuals. There is a lack of data on the molecular basis for ‘Asia type’ DELs with weak RhD phenotype. Therefore, the aim of this study is to unveil ‘Asia type’ DELs by elucidating the genetic background and analyzing
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Infectious diseases and the impact on transfusion medicine: A historical review and lessons for the future Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-06-14 Valéria de Freitas Dutra, Carolina Bonet-Bub, Araci Massami Sakashita, José Mauro Kutner
Blood transfusion saves millions of lives each year. It is a well-established treatment, and many procedures are applied to avoid transmitted infections. However, throughout the history of transfusion medicine, many infectious diseases arose or were recognised, bringing up an impact on the blood supply, as the difficulties in diagnosing new diseases, the decrease in blood donors, the challenges for
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A comparative evaluation of the quality of cryoprecipitate prepared from 350 ml versus 450 ml of whole blood and different methods of thawing of plasma: A prospective observational study Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-06-14 M. Sree Bhgavathi, Satya Prakash, Gaurav Chhabra, Ansuman Sahu, Debasish Mishra, Somnath Mukherjee
Introduction Cryoprecipitate is used in conditions like hypofibrinogenemia, massive transfusion with bleeding, and factor XIII deficiency. The current guidelines support the preparation of cryoprecipitate from 450 ml whole blood. But 350 ml of whole blood collection is expected from low body weight (<55 kg) donors. However, no standardized criteria exist for preparing cryoprecipitate from 350 ml of
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Comparison of restrictive and liberal red blood cell suspension transfusion and analysis of influencing factors on prognosis of premature infants Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-06-13 Zhi Zeng, Yu-Dan Chen, Ming-Wei Yin, Xue-Jun Chen, Ting Wang, Jun Xu, Ji-Hua Ma
Objective To investigate the influence of restrictive and liberal red blood cell suspension (RBCs) transfusions on the prognosis of premature infants and to analyze the influencing factors to provide a reference for the transfusion strategy of preterm infants. Methods Retrospective analysis was conducted on 85 cases of anemic premature infants treated in our center, including 63 cases in the restrictive
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CAR-T Cell Therapy in India: Challenges and Opportunities for Advancement Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-06-07 Tarun Kumar Suvvari, Vinay Suresh, Krish Patel, Ananya Arora, Aman Bhonsale, Rahul Jena, Vivek Sanker
Abstract not available
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Determination of Rh type and gender using circulating cell-free fetal DNA in early pregnancy of Rh negative women in turkey Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-04-26 Tugba ELGUN, Yasemin MUSTERI OLTULU, Asiye YURTTAS GOK, Umut AGYUZ, Ulkan KILIC
Introduction Choosing the right clinical approach for early and reliable diagnosis/screening is becoming more important day by day. The aim of the study was to determine the early RhD type with cff-DNA obtained from maternal plasma, especially in the light of recent developments. In this way, it is aimed to apply Rh Ig only to mothers who are determined to have RhD (+) fetuses and to prevent unnecessary
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Imperishable blood stains splattered for Humanity: Reappraising the Shroud of Turin Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-04-26 Manish Raturi
Abstract not available
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Reduced levels of hepcidin associated with lower ferritin concentration and increased number of previous donations in periodic blood donors: A pilot study Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-04-20 Maria Vasco, Giuseppe Signoriello, Michele Scognamiglio, Giusi Moccia, Paola Filauri, Annunziata Sansone, Ilaria Matarazzo, Carmela Fiorito, Vincenzo Grimaldi, Mario Viglietti, Riccardo Toce, Raffaella Congi, Maria Assunta Di Pastena, Giuditta Benincasa, Claudio Napoli
Background Hepcidin is one of the major negative regulators of iron balance. Periodic blood donors are highly susceptible to iron deficiency. Our goal was to evaluate the possible association between serum hepcidin levels and iron homeostasis parameters in periodic blood donors. Materials and Methods We enrolled a total of n = 39 periodic healthy blood donors (n = 24 M and n = 15 F). A solid phase
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How do I forecast tomorrow’s transfusion: Are there any future and/or any breakthroughs for cell banking and transfusion medicine? Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-04-20 Olivier Garraud
Abstract not available
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Prevalence and treatment of anemia and secondary iron overload in patients with a myelodysplastic syndrome: Real-world data from a multicenter cohort study Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-04-14 Camiel L.M. de Roij van Zuijdewijn, Peter E. Westerweel, Martin R. Schipperus, Johannes F.M. Pruijt, Arjan A. van de Loosdrecht, Aart Beeker
Background anemia is the most common finding in patients with a myelodysplastic syndrome (MDS). Repetitive red blood cell (RBC) transfusions and disease-related low hepcidin levels induce secondary iron overload. Real-world data on the prevalence and treatment strategies of anemia and secondary iron overload in MDS patients, is limited. Methods three years of data on MDS diagnosis, anemia and ferritin
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Pathophysiological, immunogenetic, anatomopathological profile of thrombophilia in pregnancy Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-04-05 Chaimae Hilali, Sara Aboulaghras, Najat Lamalmi
Thrombophilic states have been associated with early and/or late pregnancy loss and possibly other severe obstetrical complications. Pregnancy-induced hypercoagulability, increased stasis, and the consequences of inherited and acquired thrombophilia are just a few of the factors that contribute to the development of thrombosis in pregnancy. In this review, we illustrate the impact that these factors
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Mesenchymal – Stem and non-Stem – Cells: The name of the rose Transfus. Clin. Biol. (IF 1.7) Pub Date : 2023-04-05 Zoran Ivanovic
Abstract not available