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Erratum to "Diamantis S, Longuet P, Lesprit P, Gauzit R. Terms of use of outpatient parenteral antibiotic therapy" Med Mal Infect. 2020 Jun 20:S0399-077X(20)30153-0. doi: 10.1016/j.medmal.2020.06.004. Med. Mal. Infect. (IF 5.0) Pub Date : 2020-11-22 S Diamantis,P Longuet,P Lesprit,R Gauzit
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COVID-19 in clinical practice: A narrative synthesis Med. Mal. Infect. (IF 5.0) Pub Date : 2020-09-29 M. Le Maréchal, P. Morand, O. Epaulard, B. Némoz
The coronavirus disease 2019 (COVID-19) was first reported in the city of Wuhan, China. The disease rapidly spread to the rest of China, to Southern-East Asia, then to Europe, America, and on to the rest of the world. COVID-19 is associated with a betacoronavirus named SARS-CoV-2. The virus penetrates the organism through the respiratory tract, conveyed by contaminated droplets. The main cell receptor
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A six-week antibiotic treatment of endocarditis with spondylodiscitis is not associated with increased risk of relapse: a retrospective cohort study Med. Mal. Infect. (IF 5.0) Pub Date : 2020-11-06 B. Castagné, M. Soubrier, J. Prouteau, N. Mrozek, O. Lesens, A. Tournadre, E. Gadea, M. Vidal
Background: We compared the relapse rate at 1 year in patients with vertebral osteomyelitis with or without associated endocarditis. Patients and methods: We conducted a retrospective cohort study. Inclusion criteria were patients hospitalized in the infectious disease, rheumatology, cardiology, cardiovascular surgery and two internal medicine units for vertebral osteomyelitis (blood culture and/or
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Personal beliefs and misconceptions, not evidence guide general practitioners in the managing of travelers’ diarrhea: results from a pilot study (North-Western Italy, 2019) Med. Mal. Infect. (IF 5.0) Pub Date : 2020-11-04 Matteo Ricco’, Giovanni Gualerzi, Silvia Ranzieri
Background: The present study aims to characterize knowledge, attitudes and practices in a sample of general practitioners (GPs) on management of travelers’ diarrhea (TD). Methods: A total of 158 GPs (44.3% males; mean age 40.2 ± 12.4 years) completed a web questionnaire on antibiotic prophylaxis (AP) and/or an antibiotic treatment (AT) in TD cases. Participants were inquired on knowledge status (KS)
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Microcephaly Epidemic in Brazil: An Earlier Chapter Med. Mal. Infect. (IF 5.0) Pub Date : 2020-11-02 Alexandre Medeiros de Figueiredo, Pablo Sanchez Villegas, Daniela Cristina Moreira Marculino de Figueiredo, Juliana Sousa Soares de Araujo, Antonio Daponte
Objective: Identify risk factors for microcephaly and evaluate historical trends of microcephaly and arboviruses to recognize patterns and anomalies that indicate the beginning of the microcephaly epidemic associated with Zika infection. Methods: The head circumferences of 62,298 newborns was analyzed to identify cases of microcephaly between 2014 and 2017. We compared the groups of newborns with normal
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Elizabethkingia anophelis meningitis in a traveler returning from the Americas. Med. Mal. Infect. (IF 5.0) Pub Date : 2020-11-02 Nicolas Auffret,Radu Anghel,Sylvain Brisse,Brice Rey,Déborah Schenesse,Olivier Moquet
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Antibiothérapie intra-veineuse à domicile et bon usage des diffuseurs / Home intravenous antibiotherapy and the proper use of elastomeric pumps Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-22 Sylvain Diamantis, Yadar Dawudi, Bruno Cassard, Pascal Longuet, Philippe Lesprit, Rémy Gauzit
Over several decades, the economic situation and consideration of patient quality of life have been responsible for increased outpatient treatment. It is in this context that outpatient antimicrobial treatment (OPAT) has rapidly developed. The availability of elastomeric infusion pumps has permitted prolonged or continuous antibiotic administration by dint of a mechanical device necessitating neither
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Rothia spp. infective endocarditis: a systematic literature review Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-22 F Franconieri, O Join-Lambert, C Creveuil, M Auzou, F Labombarda, A Aouba, R Verdon, A de La Blanchardière
Objective: To describe the epidemiological, clinical, microbiological, and therapeutic features and outcomes of Rothia infective endocarditis (RIE) and extracardiac infections (ECRI). Methods: We performed a systematic literature review of published cases of RIE and ECRI. Results: After inclusion of a personal case report, 51 cases of RIE and 215 cases of ECRI were reported. Compared with ECRI patients
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Impact of Admission to High-Risk Isolation Room on Patients' and Healthcare Workers' Perceptions: a Qualitative Cross-assessment Approach Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-22 Gisele Bendjelloul, Sandrine Gerard, Gabriel Birgand, Floriane Lenne, Christophe Rioux, Xavier Lescure, Yazdan Yazdanpanah, Jean-Christophe Lucet
Introduction: High-risk isolation units (HRIU) house patients at high risk of transmitting infectious agents, notably patients with suspected viral hemorrhagic fever or smear-positive tuberculosis. Admission to HRIU can alter the quality of care and impact patients’ and healthcare workers’ (HCWs) anxiety and dissatisfaction. Methods: The Infectious Diseases Department of the Bichat Claude Bernard Hospital
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Early symptomatic neurosyphilis and ocular syphilis: a comparative study between HIV-positive and HIV-negative patients Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-22 V. Rasoldier, J. Gueudry, C. Chapuzet, B. Bodaghi, M. Muraine, R. Tubiana, L. Paris, M. Pestel-Caron, F. Caron, E. Caumes
Objectives: Since the 2000s, there has been an increase in prevalence of neurosyphilis (NS) and ocular syphilis (OS). As data about symptomatic NS/OS is limited, this study aims to assess the characteristics of symptomatic NS/OS, according to HIV status. Methods: We compared the clinical and biological presentation of early symptomatic NS/OS and its outcome in HIV-positive and HIV-negative patients
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Focus on patients receiving long-term antimicrobial treatments for Lyme borreliosis: no Lyme but mostly mental disorders Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-21 Oula Itani, Elie Haddad, Victor Pitron, François Pichon, Eric Caumes
Objectives: Overdiagnosis of Lyme borreliosis leads to unnecessary and increasingly common antimicrobial treatments. We aimed to evaluate patients receiving long-term antimicrobial treatment for Lyme borreliosis. Methods: We included patients referred to a Parisian teaching hospital between January 1st, 2014 and June 30th, 2019, with a presumed diagnosis of Lyme borreliosis for which they were treated
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Does a 5-day course of antibiotics in elderly patients with community-acquired pneumonia achieve the established criteria of clinical stability? Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-20 C. Flateau, M. Dinia, N. Raulet, S. Sayegh, S. Diamantis, M. Jager
Objective: We aimed to determine, the proportion of elderly patients hospitalized for community-acquired pneumonia (CAP) in whom a 5-day antibiotic therapy would achieve clinical stability according to American Thoracic Society (ATS) criteria. Methods: Patients aged > 75 years, hospitalized for CAP between November 2018 and August 2019, were analyzed retrospectively. The American Thoracic Society (ATS)
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Number, type and cost of microbiological tests during HIV Pre-Exposure Prophylaxis: the experience of a French hospital Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-20 M. Morgat, K. Bouiller, JB Vuillemenot, L. Puget, S. Marty-Quinternet, T. Leblanc, K. Jeannot, C. Chirouze, L. Hustache-Mathieu, Q. Lepiller
Background: microbiological tests are required for individuals on HIV Pre-Exposure Prophylaxis (PrEP), but their real-life numbers, types and cost are poorly described. Methods: number, type, and results of microbiological tests performed in a Besançon Hospital-associated laboratory, France, from 2016 to 2019, in the setting of PrEP consultations were retrospectively collected. Costs were estimated
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SEVERE ADVERSE EVENTS DURING MEDICAL AND SURGICAL TREATMENT OF HIP AND KNEE PROSTHETIC JOINT INFECTIONS Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-20 S. Perez, F-A. Dauchy, F. Salvo, M. Quéroué, H. Durox, P. Delobel, R. Chambault, M. Ade, C. Cazanave, A. Desclaux, T. Fabre, H. Dutronc
Introduction: The management of prosthetic joint infection requires a complex treatment procedure and can be associated with complications. However, the occurrence of severe adverse events during this intervention has been poorly evaluated. Patients and methods: A 5-year multicentric retrospective study including patients from 3 hospitals in the South-Western France referral center for complex bone
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Compassionate use of cefiderocol in a pancreatic abscess and emergence of resistance. Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-22 C Grande Perez,E Maillart,V Y Miendje Deyi,T-D Huang,P Kamgang,Y Dernier,P Clevenbergh
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Determinants of doctors’ antibiotic prescriptions for patients over 75 years old in the terminal stage of palliative care Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-16 M Durand, E Forestier, C Gras Aygon, S Sirvain, B de Wazières, L Bernard, M Paccalin, L Legout, C Roubaud Baudron, G Gavazzi, T Fraisse
Introduction: Notwithstanding high prevalence of presumably bacterial infections in elderly persons (EP) in palliative care (PC), there exists no recommendation on the role of antibiotic therapy (ABP) in this type of situation. Objective: To describe the determinants of antibiotic prescription by general practitioners (GP) and by doctors practicing in institutions (DPI) for patients > à 75 years, in
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Connaissance de l’infection à Chlamydia trachomatis des personnes consultant en centre de dépistage et occasions manquées de dépistage en soins primaires Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-16 C Pépin, F Souala, E By, M Bérar, C Arvieux, F Fily
Objectifs: Décrire la connaissance sur l’infection à Chlamydia trachomatis des personnes consultant en centre de dépistage d’Ille-et-Vilaine et les occasions manquées de dépistage en soins primaires dans les 6 mois précédant un diagnostic. Patients et méthode: Etude transversale incluant les personnes de plus de 15 ans consultant dans les centres de Rennes et Saint-Malo entre le 08/04/19 et le 01/07/19
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Influenza vaccination coverage at community pharmacies: positioning, needs, expectations and involvement of community pharmacists in the Franche-Comté Region Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-16 M Kroemer, AL Clairet, K Kabiche, A Bendjama, X Bertrand, S Limat, V Nerich
Introduction: Influenza vaccination coverage currently remains below the 75% recommended threshold by the World Health Organization. To correct this situation, experiments have been successively carried out in France to enable community pharmacists to vaccinate at-risk populations. In this context, a study was conducted with pharmacists from the French Franche-Comté Region to evaluate their positioning
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The vaccination coverage in dispensaries on Mayotte Island is lacking for natives and migrants alike Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-15 Clelia Pascal, Olivier Lesens
Objective: Assessing the vaccination coverage rate in Mayotte dispensaries Patients and methods: prospective study in three dispensaries from June to July 2019 Results: Of the 162 patients included, 78% (126/162) were natives of the island and 19% (30/162) were from the Comoros Islands. 23% (37/162) were up-to-date on their mandatory vaccinations, 45% (73/162) were not and 32% (52/162) had unknown
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Pulmonary tuberculosis: Evaluation of current diagnostic strategy Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-15 SB Gressens, T. Billard-Pomares, H. LeBoité, P. Cruaud, O. Bouchaud, E. Carbonnelle, F. Méchaï
Objective: To identify tools that will result in faster diagnosis, making the current pulmonary tuberculosis strategy more efficient Patients and methods: A 4-year (2015 – 2018) retrospective study. The gold standard for diagnosis was a positive culture from a respiratory specimen. All sputum, fibroscopy and post-fibroscopy specimens (for smear negative patients) were collected. Each specimen was analyzed
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Travellers’ Risk Behaviors and Health Problems: Post-Travel Follow Up in Two Travel Medicine Centers in Italy Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-15 Armando Stefanati, Alice Pierobon, Valeria Baccello, Emanuela DeStefani, Diego Gamberoni, Patrizia Furlan, Federica Sandri, Antonio Stano, Paolo Coin, Vincenzo Baldo, Giovanni Gabutti
Objectives: We examined the association between travellers’ characteristics, compliance with pre-travel recommendations and health problems. Methods: Volunteer travellers were enrolled and data collected using a questionnaire between 30-60 days after returning home. We analyzed the associations through bivariate and multivariate models. Results: Of the 468 enrolled travelers, 68% consumed raw food
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Erythematous skin nodules during treatment of Whipple's disease. Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-16 A Sanchez,P Del Giudice,C Mantion,S Mazellier,F Boukari,P-M Roger,J Courjon
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Compliance with antibiotic prophylaxis guidelines in surgery: Results of a targeted audit in a large-scale region-based French hospital network Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-14 Nicolas Prévost, Aurélie Gaultier, Gabriel Birgand, Julie Mocquard, Noémie Terrien, Elise Rochais, Romain Dumont
Introduction. While regional monitoring of antibiotic use has decreased since 2011 by 3.2%, in some healthcare facilities a significant increase (+43%) has occurred. The purpose of this study was to assess regional antibiotic prophylaxis (ABP) compliance with national guidelines. Material and methods. In 2015, 26 healthcare facilities, both public and private, were requested to audit five items: utilization
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Antivirals in the time of COVID-19 - not as easy as it looks! Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-15 F Trémolières
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Infectious complications of promontofixation, A systematic review of the literature Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-13 T. Grevez, V. Vanalderwerelt, F. Bruyère
Introduction : Surgery for genitourinary prolapse may be complicated, with post-operative infections. While promontofixation is recommended and widely used, the impact of postoperative infections has received little study. We consequently decided to review the literature to identify risk factors for infection. Material and method: We conducted a systematic review of the literature. PubMed, Medline
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Evolution entre 2008 et 2018 de la perception des mères vis-à-vis de la vaccination et des couvertures vaccinales des nourrissons en France Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-12 A. Martinot, B. Leboucher, R. Cohen, J-P Stahl, D. Subtil, P. Pujol, H. Lepetit, L. Longfier, J. Gaudelus
Objectifs : Le suivi des couvertures vaccinales (CV) est essentiel pour évaluer l’application de la politique vaccinale d’un pays et évaluer son efficacité. Au travers de l’enquête française Vaccinoscopie, nous avons mesuré l’évolution des CV et de la perception des mères vis-à-vis de la vaccination entre 2008 et 2018, avant et après l’extension de la vaccination obligatoire du nourrisson en France
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Genesis and dissemination of a controversial disease: chronic Lyme Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-10 X Gocko, P Tattevin, C Lemogne
Objectives: To describe the role of the internet and cognitive biases in the controversy surrounding chronic Lyme disease. The attribution of chronic but aspecific symptoms to Lyme borreliosis is a source of worldwide controversy. Patients and methods: Some patients attribute their aspecific symptoms to Lyme borreliosis even though, in fact, they have a functional somatic syndrome. Results: These patients’
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Bacteria which are highly resistant to antibiotics are not resistant hydro-alcoholic products Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-08 C. Ciotti, B. Ferrao, I. Garrigues, S. Nérome
Aims: Methods and materials: The product was tested using the dilution-neutralization method using the NF/EN 13727+A2 standard on Staphylococcus epidermidis which is resistant to methicillin and has a reduced reaction to glycopeptide antibiotics, on Enterococcus faecium which is resistant to glycopeptides, as well as on Klebsiella pneumoniae and Pseudomonas aeruginosa which produce carbapenemases.
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The role of alternative and complementary medical practices in vaccine hesitancy among nurses: a cross-sectional survey in Brittany Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-08 A. Thomire, J. Raude
Introduction Dans un contexte de remise en cause croissante de la vaccination, nous avons étudié le lien entre recours aux pratiques médicales alternatives et complémentaires (MAC) et l’hésitation vaccinale (HV) chez les infirmiers. Méthode Nous avons réalisé une étude observationnelle transversale, par questionnaire auto-administré en ligne, sur un panel d’infirmiers en Bretagne. Nous avons examiné
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COVID-19 outpatient management: Shorter time to recovery in Healthcare workers according to an electronic daily symptoms assessment Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-07 Emma Breugnon, Hadrien Thollot, Antoine Fraissenon, Florian Saunier, Rémi Labetoulle, Sylvie Pillet, Frederic Lucht, Philippe Berthelot, Elisabeth Botelho-Nevers, Amandine Gagneux-Brunon
Objectives: Our aim is to compare the course of the disease between healthcare workers (HCWs) and non-HCWs suffering from covid-19 and eligible for outpatient management. Methods: Single-center prospective cohort of outpatients with covid-19, diagnosed between the 10th March and the 2nd April, 2020 with a daily collection of symptoms by an on-line auto-questionnaire. Results: A total of 186 patients
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The Additional Contribution of Second Nasopharyngeal PCR to COVID-19 Diagnosis in Patients with Negative Initial Test Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-07 Bircan Kayaaslan, Ayse Kaya Kalem, Fatma Eser, Imran Hasanoglu, Rahmet Guner
Objective: The World Health Organization (WHO) recommends performing a second test in patients with a high suspicion of novel coronavirus disease (COVID-19) whose first PCR test is negative. However, the additional contribution of the second PCR test to the diagnosis is unknown. Patients and methods: In this study, we aimed to investigate the contribution of second SARS-CoV-2 PCR to diagnosis in patients
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Miliary tuberculosis secondary to intravesical instillation of Bacillus Calmette-Guérin. Report of two cases. Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-07 R Gálvez-López,E Ruiz-Carazo,A J Láinez-Ramos-Bossini,A J García Salguero,M C Pérez-García,M Rabadán-Caravaca
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Hemophagocytic lymphohistiocytosis secondary to disseminated histoplasmosis in an immunocompetent patient. Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-07 D Song,J Wang,Z Wang
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Neuroretinitis caused by Toxoplasmagondii as an unusual presentation of acquired immunodeficiency syndrome (AIDS). Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-07 M Pichon,C Fardeau,P Genet,M Abderrahmane,B Wifaq,A-M Menn
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About three cases of Mycobacterium bovis bone and joint infections after BCG therapy. Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-07 M Ducours,A Desclaux,H Dutronc,F A Dauchy,M L Abi-Chahla,V Pointillart,G Wirth
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Comamonas testosteroni appendicitis: About a case and review of the literature. Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-07 M Miloudi,Y El Kamouni,H Oulhadj,L Arsalane,S Zouhair
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Epidemiology and clinical analysis of the breakout of dengue fever in Zhangshu City, Jiangxi Province in 2019 Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-04 Jingen Wang, Qiubo Chen, Zhongbao Jiang, Xiaoju Li, Huiping Kuang, Ting Chen, Feng Liu, Wujuan Zhou, Yanxia Huang, Yong Luo, Jianfeng Rao, Ju Weihua, Wang Li, Xuping Peng, Zhicheng Zhang, Hongyi Chen
Objective: To analyze the epidemiological and clinical features of dengue fever in Zhangshu in 2019 and provides evidence for the treatment, prevention and control of dengue fever. Methods: The study included 718 dengue fever patients. The epidemiological data and clinical features of patients were collected and counted. Multiple adjuvant therapies were applied to patients and were used to detect the
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Clinical trial protocols of repurposed prophylaxis for COVID-19: a review Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-03 Erwan Sallard, Drifa Belhadi, François-Xavier Lescure, Yazdan Yazdanpanah, Nathan Peiffer-Smadja
Efficient therapeutic strategies are needed to counter the COVID-19 pandemic, caused by the SARS-CoV-2 virus. In a context where specific vaccines are not yet available, the containment of the pandemic would be facilitated with efficient prophylaxis. We screened several clinical trials repositories and platforms in search of the prophylactic strategies being investigated against COVID-19 in July 2020
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Low Immune Response Rate of HIV-Infected Patients to a Single Injection of Hepatitis A Vaccine Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-03 Lucie Noel, Roland Tubiana, Anne Simon, Marc-Antoine Valantin, Romain Palich, Christine Blanc, Christine Katlama, Anne-Geneviève Marcelin, Vincent Calvez, Eve Todesco
Objectives: We aimed to evaluate the immune response of HIV-1 positive patients to a single injection of HAV vaccine in a context of vaccine shortage during the 2017 European outbreak. Methods: We retrospectively enrolled all HIV-1 positive patients vaccinated by a single injection of HAV vaccine Vaqta 50®. HAV serology was performed before and >30 days after the vaccine injection. Results: Among the
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How should a positive PCR test result for COVID-19 in an asymptomatic individual be interpreted and managed? Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-03 C Esteve, FX Catherine, P Chavanet, M Blot, L Piroth
The rapidly increasing number of PCR-based SARS-CoV-2 tests as COVID-19 control measures has been leading not only to the discovery of positive results in asymptomatic individuals, but also to the re-testing of persons having contracted (proven or unproven) COVID-19 or having previously tested positive. In the face of interrogations as to the interpretation and management of these types of situations
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Is a COPD patient protected against SARS-CoV-2 virus? Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-03 C Daubin,A Justet,A Vabret,E Bergot,N Terzi
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First evaluation of the automated-multiplex-PCR Unyvero ITI G2 cartridge for rapid diagnosis of osteo-articular infections Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-01 E. Lafeuille, S. Jauréguiberry, F. Devriese, E. Sadowski, E. Fourniols, A. Aubry
Objective: Conventional microbiological methods (CMM), including long-term culture, for the diagnosis of osteo-articular infections (OAI) fail in at least 5% of all cases. Only one IOA dedicated molecular method has been commercialized, and only the first version of this kit has been studied. The aim of this work was to evaluate the concordance between test results obtained with the second version
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First case of mild encephalopathy with reversible splenial lesion in SARS-CoV-2 infection Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-01 J. Chauffier,N. Poey,M. Husain,T. de Broucker,A. Khalil,S. Lariven,M.-C. Henry-Feugeas
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Catheter-related bacteremia with endocarditis caused by Kocuria rhizophila. Med. Mal. Infect. (IF 5.0) Pub Date : 2020-10-01 A Pierron,S Zayet,L Toko,P Y Royer,P Garnier,V Gendrin
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HLA Class II alleles and association with HPV Infection prevalence in high-risk HPV-positive Han women in southern China Med. Mal. Infect. (IF 5.0) Pub Date : 2020-09-29 Zhongzheng Zheng, Qingqing He, Lin An, Daiyang Li, Ningjuan Wang, Liping Wang, Qin Sun, Jian Wang, Peili Xiao, Du Keming, Boan Li
Objective: To investigate the prevalence of different human papillomavirus (HPV) subtypes and their association with human leukocyte antigen (HLA) class II alleles in China. Patients and methods: A total of 16,168 married Chinese women in Maoming City of Guangdong province were tested for high-risk HPV infection. High-resolution typing of HLA-DRB1/DQB1 alleles was also performed on samples found to
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Increased risk of IRIS-associated tuberculosis in HIV-infected patients receiving Integrase Inhibitors Med. Mal. Infect. (IF 5.0) Pub Date : 2020-09-29 Antoine Gaillet, Ruxandra Calin, Philippe Flandre, Roland Tubiana, Marc-Antoine Valantin, Eric Caumes, Christine Katlama, Valérie Pourcher
Background: Tuberculosis is associated with a risk of immune reconstitution inflammatory syndrome (IRIS) after ART initiation. Methods: Data from all patients with newly diagnosed tuberculosis disease and uncontrolled HIV infection from 1997 to 2017 in a French center were retrospectively collected. We evaluated the incidence of tuberculosis-IRIS in patients initiating ART with or without integrase
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Two Natural Recombination gave rise to the Coxsackievirus B3 GⅤ that triggered outbreaks in China in 2006 - 2012 Med. Mal. Infect. (IF 5.0) Pub Date : 2020-09-29 Hua Wang, Yongjiang Qian, Chunhua Qian, Chun Dai, Hongxing Shen
Coxsackievirus B3 serotype GⅤ caused the epidemic of Coxsackievirus B3 infection in China from 2006 to 2012. To study the evolution and recombination of Coxsackievirus B3 serotype GⅤ, we performed recombination and phylogenetic analysis of 499 complete genomes of Enterovirus B available in GenBank, dated April 2019. Results indicated that most of the strains of Coxsackievirus B3 GⅤ in P1 region were
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Jaundice in a patient treated with Anakinra in a context of Covid-19. Med. Mal. Infect. (IF 5.0) Pub Date : 2020-09-30 H Tarhini,M Husain,N Poey,S Lariven,F-X Lescure,Y Yazdanpanah,A Gervais
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Intravesical BCG instillation as a possible cause of acute and chronic kidney injury. Med. Mal. Infect. (IF 5.0) Pub Date : 2020-09-29 Y Tamzali,M Jamme,F Bottet,M Gauthe,E Rondeau,G Pialoux,R Calin
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Evaluating family physicians' willingness to prescribe PrEP. Med. Mal. Infect. (IF 5.0) Pub Date : 2020-08-26 France Villeneuve,Jean-Michel Cabot,Sabrina Eymard-Duvernay,Laurent Visier,Vincent Tribout,Cyril Perollaz,Jacques Reynes,Alain Makinson
Introduction We assessed family physicians’ (FP) willingness to integrate PrEP into their clinical practice in Montpellier and its surroundings. Method We aimed to randomly assess 92 FPs. Results Ninety-six FPs were interviewed from May to December 2018: 78% (95% CI [69; 86]) were willing to integrate PrEP, 65% to be trained, and 52% to be the first providers. Of the 65 (6%) with some knowledge of
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Fosfomycin, from susceptibility to resistance: Impact of the new guidelines on breakpoints. Med. Mal. Infect. (IF 5.0) Pub Date : 2020-07-15 E Farfour,N Degand,E Riverain,V Fihman,C Le Brun,G Péan de Ponfilly,A Muggeo,A Jousset,C Piau,P Lesprit,
The fosfomycin breakpoint using the disc diffusion method (DDM) changed in the 2019 CA-SFM/EUCAST guidelines v2 (24 mm versus 19 mm). We assessed its impact on categorization of Enterobacterales recovered from urine samples in emergency departments. A total of 7749 and 2348 strains were tested using the DDM and the broth microdilution method (BMD), respectively. The DDM with the 19-mm breakpoint was
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2010 French SPILF-AFSSAPS guiding criteria for Streptococcus pneumoniae acute community-acquired pneumonia: evaluation in patients of the PACSCAN-ESCAPED cohort. Med. Mal. Infect. (IF 5.0) Pub Date : 2020-09-17 M Ben Hayoun,S Tubiana,E Varon,J M Naccache,H Le Floch,C Leport,Y E Claessens,X Duval,
Objective. To assess the proportion of patients meeting the 2010 SPILF-AFSSAPS guiding criteria for Streptococcus pneumoniae in patients consulting at the emergency departments of four French university hospitals for acute community-acquired pneumonia (CAP) suspicion. Patients and methods. The PACSCAN study prospectively included 319 patients. Medical history, clinical, biological, and radiological
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[Capnocytophaga canimorsus meningitis]. Med. Mal. Infect. (IF 5.0) Pub Date : 2020-09-08 A Galles,E Monlun,L Villeneuve,S Poirot-Mazères
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Compliance with antibiotic guidelines by urologists. Med. Mal. Infect. (IF 5.0) Pub Date : 2020-09-06 M Vallée,F Bruyère,E Bey,C Duran,C Le Goux,A Sotto,A Dinh,
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Cerebral phaeohyphomycosis in an immunocompetent patient. Med. Mal. Infect. (IF 5.0) Pub Date : 2020-09-06 X-C Tong,Y-L Qiu,H-W Wang,F-R Tan,S-Q Ben,T-M Xu
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Infections de l’immunodéprimé (hors VIH) Med. Mal. Infect. (IF 5.0) Pub Date : 2020-09-01 H. Mascitti
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Rôle de l’infirmière et du cadre infirmier lors de la mise en place urgente d’une équipe de dépistage autour d’un cluster de coronavirus Med. Mal. Infect. (IF 5.0) Pub Date : 2020-09-01 C. Paget,S. Arioli,C. Grillet,E. Morel,L. Lannou,G. Moreau,I. Pellarin,S. Flattres,F. Rica
Introduction La découverte d’un cluster autour d’un cas d’infection à coronavirus Covid-19 dans une commune française a déclenché la création d’une cellule de crise. Une équipe d’intervention a dû être constituée 24h après cette découverte pour dépister les contacts d’un enfant infecté appartenant à ce cluster. Celle ci était composée d’une équipe médicale et paramédicale d’infectiologie, d’un médecin
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La supervision, un élément central pour la sécurisation de la prise en charge des patients infectés par le SARS-CoV-2 Med. Mal. Infect. (IF 5.0) Pub Date : 2020-09-01 G. Bendjelloul,S. Gerard,S. Jacques,F. Essardy,D. Saint Leandre,F. Millon,I. Lolom,N. Ammar-Khodja,Y. Yazdanpanah,J. Lucet
Introduction Notre hôpital a pris en charge dès janvier 2020 des patients infectés par le SARS-CoV-2 et organisé une prise en charge (PEC) des cas possibles en ambulatoire. Nous rapportons ici l’organisation paramédicale, centrée sur le principe de la supervision. Matériels et méthodes Trois patients ont été hospitalisés en maladies infectieuses (SMIT) et 1 en réanimation médicale. Un patient du SMIT
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Audit des connaissances et utilisation des différents dispositifs intravasculaires Med. Mal. Infect. (IF 5.0) Pub Date : 2020-09-01 F. Arnault,A. Clochard,C. Couder,C. Lamarre,A. Male,A. Moreau,D. Coindre,N. Hays,M. Catroux,F. Cazenave-Roblot
Introduction Les dispositifs intravasculaires sont nombreux. Ceux de longue duree sont devenus des outils incontournables. Les connaissances et pratiques dans les services sont differentes malgre l’existence d’un protocole institutionnel. L’objectif de ce travail est de faire un etat des lieux de l’utilisation de ces dispositifs au sein de l’etablissement et harmoniser les bonnes pratiques. Materiels
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Un espoir pour le traitement des infections ostéo-articulaires : les éponges à base de chitosan/polymère de cyclodextrines Med. Mal. Infect. (IF 5.0) Pub Date : 2020-09-01 D. Laoubi,A. Gauzit-amiel,M. Maton,C. Neut,B. Martel,N. Blanchemain
Introduction Les infections osteo-articulaires (IOA) sont un probleme de sante publique. Les therapies actuelles ne sont pas toujours efficaces et l’amputation est souvent la seule issue. De nouvelles strategies therapeutiques sont developpees : les systemes de liberation localisee. Dans notre cas, ce sont des eponges a base de chitosan (CHT) et de polymere de cyclodextrine (PCDs) impregnees de rifampicine