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Unusual presentation of disseminated gonococcal infection Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-03-15 Mariam AlHammadi, Aaron Schembri, Luca Calleja, Valeska Padovese
A 30-year-old homosexual man living with HIV and receiving virologically suppressive antiretroviral treatment presented to the emergency department with a 3-day history of pain in his left wrist accompanied by fever and chills. On examination, the left wrist showed redness, swelling, tenderness and decreased range of movement. The patient had no history of trauma, insect bites or scratches. Four weeks
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Assessing the effectiveness of HIV/STI risk communication displays among Melbourne Sexual Health Centre attendees: a cross-sectional, observational and vignette-based study Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-23 Phyu Mon Latt, Nyi Nyi Soe, Christopher Fairley, Xianglong Xu, Alicia King, Rashidur Rahman, Jason J Ong, Tiffany R Phillips, Lei Zhang
Introduction Increasing rates of sexually transmitted infections (STIs) over the past decade underscore the need for early testing and treatment. Communicating HIV/STI risk effectively can promote individuals’ intention to test, which is critical for the prevention and control of HIV/STIs. We aimed to determine which visual displays of risk would be the most likely to increase testing or use of prevention
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Multicentric evaluation of a specific intrathecal anti-Treponema pallidum IgG index as a diagnostic biomarker of neurosyphilis: results from a retro-prospective case–control study Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-03-01 Chloé Alberto, Nathalie Lambeng, Christine Deffert, Gautier Breville, Angèle Gayet-Ageron, Patrice Lalive, Alexandra Calmy, Alix Coste, Matthaios Papadimitriou-Olivgeris, Dominique Braun, Reto Lienhard, Philipp Peter Bosshard, Lionel Fontao, Laurence Toutous Trellu
Background and objectives The diagnosis of neurosyphilis (NS) lacks a true ‘gold standard’, making the diagnosis challenging while consequences of a misdiagnosis are potentially severe. The aim of this study was to evaluate the diagnostic performance of measuring an antibody index (AI) for the intrathecal synthesis of specific anti- Treponema pallidum ( T. pallidum ) IgG for the diagnosis of NS. Methods
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Modelling the impact of vaccination and sexual behaviour adaptations on mpox cases in the USA during the 2022 outbreak Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-03-01 Patrick A Clay, Jason M Asher, Neal Carnes, Casey E Copen, Kevin P Delaney, Daniel C Payne, Emily D Pollock, Jonathan Mermin, Yoshinori Nakazawa, William Still, Anil T Mangla, Ian H Spicknall
Background The 2022 mpox outbreak has infected over 30 000 people in the USA, with cases declining since mid-August. Infections were commonly associated with sexual contact between men. Interventions to mitigate the outbreak included vaccination and a reduction in sexual partnerships. Understanding the contributions of these interventions to decreasing cases can inform future public health efforts
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Point-of-care testing for sexually transmitted infections and HIV pre-exposure prophylaxis among pregnant women in South Africa, 2021–2022: randomised controlled trial Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-03-01 Alex de Voux, Dorothy Chiwoniso Nyemba, Miriam Silliman, Nyiko Mashele, Rufaro Mvududu, Landon Myer, Dvora Joseph Davey
Objective Pregnant and postpartum women (PPW) in Southern Africa are at increased risk of acquiring HIV and curable sexually transmitted infections (STIs). Oral pre-exposure prophylaxis (PrEP) is safe and effective to use during pregnancy to reduce HIV acquisition and vertical transmission. Point-of-care (POC) STI testing can identify PPW at risk of HIV and facilitate risk-differentiated and person-centred
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Sexual network characteristics and partnership types among men who have sex with men diagnosed with syphilis, gonorrhoea and/or chlamydia in Lima, Peru Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-03-01 Jonathan Freese, Eddy R Segura, Jessica Gutierrez, Jordan E Lake, Robinson Cabello, Jesse L Clark, Cherie Blair
Objectives Sexual networks are known to structure sexually transmitted infection (STI) transmission among men who have sex with men (MSM). We sought to estimate the risks of STI diagnosis for various partnership types within these networks. Methods Our cross-sectional survey analysed data from 1376 MSM screened for a partner management intervention in Lima, Peru. Participants were tested for HIV, syphilis
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Acceptability of digital vending machines to access STI and HIV tests in two UK cities Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-03-01 Maya Gobin, Syra Dhillon, Joanna May Kesten, Jeremy Horwood, Gillian Louise Dean, Sarah Stockwell, Sarah Denford, John Mear, Richard Cooper, Joanna Copping, Lottie Lawson, Samuel Hayward, Lindsey Harryman, Jaime H Vera
Objectives Prompt HIV and STI diagnosis and treatment is a public health priority and relies on accessible testing. Technology-based approaches to distribute test kits have the potential to increase access to testing. We evaluated the acceptability and uptake of vending machines in publicly available settings in Brighton and Hove (BH) and Bristol, North Somerset and South Gloucestershire (BNSSG), to
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Influences affecting decision-making regarding use of pre-exposure prophylaxis among black men who have sex with men in the USA: a systematic review and meta-synthesis Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-03-01 Freddie Hutchins, Nicholas Drey
Aim To systematically identify, evaluate, and synthesise qualitative research examining positive and negative influences affecting decision-making behaviour among black men who have sex with men (BMSM) in the USA regarding use of pre-exposure prophylaxis (PrEP). Background Used correctly, PrEP is highly efficacious in preventing HIV infection and is available via healthcare services throughout the
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Painful proctitis associated with anorectal mpox, syphilis, HSV, LGV, gonorrhoea and Mycoplasma genitalium in a person living with virologically suppressed HIV and vaccinated against mpox Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-03-01 Zoe Y Huang, Vincent J Cornelisse, Rachel M Burdon
A gay man with well-controlled HIV and vaccinated against mpox presented with severe proctitis. Testing revealed anorectal mpox, herpes simplex virus, lymphogranuloma venereum, Neisseria gonorrhoeae and Mycoplasma genitalium . Serology was indicative of infectious syphilis. This case highlights the need to consider a wide range of concurrent sexually transmitted infections in patients with proctitis
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Single case of lymphogranuloma venereum on the tongue Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-03-01 Tristan Gabriel Sobral-Costas, Sergio López-Alcázar, Rafael Escudero-Tornero, Guillermo Servera-Negre, David Manuel Montenegro Pascual, Inmaculada Quiles-Melero, Elena Sendagorta Cudós
Traditionally, lymphogranuloma venereum (LGV) has been associated with disease of the genital area. However, atypical presentations and proctitis are increasingly observed. We report a case of LGV affecting the dorsum of the tongue, which presented as a very painful ulcer. The response to doxycycline (100 mg two times per day for 21 days) was satisfactory. This case may represent a paradigm shift in
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Using crowdsourcing at an academic conference to develop STI testing messaging for public dissemination Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-03-01 Alissa Davis, Eneyi Kpokiri, Chunyan Li, Suzanne Day, Xumeng Yan, Gifty Marley, Sara E Landers, Joseph D Tucker
Objectives We provide a guide to conducting a crowdsourcing activity at an international sexually transmitted infection (STI) conference to design public messaging about STI testing and disseminating that messaging via social media. Methods A speaker gave a presentation at a conference plenary session on the concepts of cocreation, crowdsourcing and designathons, and the application of these participatory
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A holistic biopsychosocial management approach for cis-gender males with chronic pelvic pain syndrome attending sexual health services: a retrospective case review Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-03-01 Paddy J Horner, Emma Connor, Sara Williams, Jessica Butterly, Megan Crofts
Objectives Chronic pelvic pain syndrome (CPPS) in men is a condition associated with significant morbidity which is typically managed in sexual health services. We introduced a modified biopsychosocial approach for managing CPPS in men, reducing use of antibiotics and evaluated its application in a retrospective case review. Methods Patients attended for a full consultation covering symptomology, onset
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How to effectively manage chronic pelvic pain syndrome in cis-gender men presenting to sexual health services using a holistic biopsychosocial approach Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-03-01 Paddy J Horner, Megan Crofts, Jessica Butterly
Chronic pelvic pain syndrome (CPPS) in men is an important, but uncommon, multifactorial condition managed in specialist sexual health services (SSHS) which can have a significant impact on a patients’ quality of life.1–3 CPPS is part of the chronic prostatitis/CPPS symptom complex with a prevalence of 8.2% (range 2.2%–9.7%).2 , A1 CPPS is defined as pelvic pain, often associated with urinary symptoms
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Mpox after vaccination: a case series Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-03-01 Inês Aparício Martins, Ana Luísa João, José Miguel Neves, Cândida Fernandes
In 2022, in response to the global mpox outbreak, Portugal introduced the Modified Vaccinia Ankara-Bavarian Nordic vaccine for at-risk groups; two intradermal doses were preferred to maximise vaccine availability. We retrospectively reviewed the clinical characteristics of vaccinated and unvaccinated patients diagnosed with mpox at a sexual health clinic in Lisbon …
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Increasing awareness of the risk of drug-induced intracranial hypertension in patients with acne requiring treatment for bacterial STI Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-03-01 Anusha Louly Nathan, Cathal O’Broin, Aoife Lally
Drug-induced intracranial hypertension (DIIH) is a condition characterised by headaches, impaired visual acuity, visual field defects and blindness as a result of papilloedema,1 where a temporal link between symptoms and medication onset can be clearly defined. Although there are limited data describing the natural course of DIIH, discontinuation of the inciting drug is only sufficient in some cases
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Reactive HIV testing and pre-exposure prophylaxis (PrEP) use in a London sexual health clinic Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-03-01 Matthew Spencer, Sheel Patel, Gary Whitlock, Ilias Mavropoulos, Alan Mcowan, Victoria Tittle
There are concerns pre-exposure prophylaxis (PrEP) may delay HIV seroconversion, but data are limited. We present a descriptive case note review of HIV testing outcomes from 56 Dean Street, a London sexual health clinic, from 1 January to 31 December 2021. Gender, age, sexual risk, PrEP history (using tenofovir disoproxil and …
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Treatment failure in scabies: a single-centre 5-year retrospective review Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-03-01 Harry Coleman, Gulshan Cindy Sethi
In 2017, the WHO formally designated scabies a neglected tropical disease.1 The prevalence of scabies is estimated to be >200 million cases worldwide. A UK study using data from the Health Information Network estimated the prevalence of scabies to be 2.27–2.81 per 1000.2 Risk factors for scabies include close contact with an infected individual, high levels of deprivation, crowded living conditions
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Prevalence of chlamydia and gonorrhea in US Air Force male basic trainees Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-03-01 Jacqueline Kate Wade, Joseph Marcus, John Kieffer, Korey Kasper, Joshua Smalley
The incidence rates of Neisseria gonorrhoeae (GC) and Chlamydia trachomatis (CT) have been increasing over the past decade.1 Despite the increased burden of disease, current guidelines recommend only screening for GC and CT in select asymptomatic men, including those with HIV or at high risk of sexually transmitted infection (STI) acquisition.2 3 Due to these recommendations, most of the data in male
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Higher Neisseria gonorrhoeae bacterial load in coinfections with Chlamydia trachomatis compared with Neisseria gonorrhoeae single infections does not lead to more symptoms Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-03-01 Helke A van Dessel, Jeanne A M C Dirks, Inge H M van Loo, Brian M J W van der Veer, Christian J P A Hoebe, Nicole H T M Dukers-Muijrers, Paul H M Savelkoul, Petra Wolffs
Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) coinfections are commonly reported; in high-risk groups up to 40% of those infected with NG are also infected with CT.1 While coinfections might happen accidentally, it has been mathematically proven that it occurs much more frequently than can be expected from random chance alone.2 However, little is known about the effect of coinfections on
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Case of Haemophilus influenzae urethritis in a male patient Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-16 Ranjit S Samra, Erica L Plummer, Lenka Vodstrcil, Catriona S Bradshaw
Non-gonococcal urethritis (NGU) is a common presentation to sexual health clinics and in a significant proportion of cases, no pathogen is detected following routine investigations.1 Haemophilus influenzae has been identified as an occasional cause of male urethritis. We report a case of H. influenzae urethritis and describe a relatively novel treatment approach. A man presented to Melbourne Sexual
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Aetiological molecular identification of sexually transmitted infections that cause urethral discharge syndrome and genital ulcer disease in Brazilian men: a nationwide study Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-15 Maria Luiza Bazzo, Hanalydia de Melo Machado, Jessica Motta Martins, Marcos André Schörner, Ketlyn Buss, Fernando Hartmann Barazzetti, Pamela Cristina Gaspar, Alisson Bigolin, Adele Benzaken, Simone Veloso Faria de Carvalho, Lidiane da Fonseca Andrade, William Antunes Ferreira, François Figueiroa, Rafael Mialski Fontana, Miralba Freire de Carvalho Ribeiro da Silva, Roberto José Carvalho Silva, Luiz
Background Little is known about the aetiology of urethral discharge syndrome (UDS) and genital ulcer disease (GUD) in Brazil due to limited access to laboratory tests and treatment based mainly on the syndromic approach. Objectives To update Brazilian treatment guidelines according to the current scenario, the first nationwide aetiological study for UDS and GUD was performed. Methods Male participants
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Understanding the association between intimate partner violence and sexually transmitted infections among women in India: a propensity score matching approach Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-14 Mahashweta Chakrabarty, Aditya Singh, Diwakar Mohan, Shivani Singh
Background Intimate partner violence (IPV) against women can significantly impact their overall health. While numerous studies in developing nations highlight the association between IPV and sexually transmitted infections (STIs), the evidence available within the Indian context remains limited. Therefore, this study aims to fill this knowledge gap by investigating the relationship between exposure
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Correction: Hepatitis A and B vaccination in gbMSM in Ireland: findings from the European MSM internet survey 2017 (EMIS-2017) Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-08 BMJ Publishing Group Ltd
White P, O'Donnell K, Brennan A, et al . Hepatitis A and B vaccination in gbMSM in Ireland: findings from the European MSM Internet Survey 2017 …
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Association of same-sex criminalisation laws and national HIV policies with HIV testing in African MSM: an ecological single-level and multilevel cross-sectional study of sub-Saharan African countries Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-08 Ngozi Kalu, Michael W Ross, Miriam Taegtmeyer, Erik Lamontagne, Sean Howell, Melissa Neuman
Background HIV incidence among men who have sex with men (MSM) in sub-Saharan Africa (SSA) remains high compared with the general population. Many countries in the region still criminalise consensual homosexual relationships, and some are yet to adopt WHO-recommended interventions for MSM into national HIV policies. This study examines how HIV testing of adult MSM in SSA varies according to the legal
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STI self-testing: ensuring representation and outreach to teens and adolescents in expanded approaches Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-02 Michael E DeWitt, Vonda Pabon, Andrea Vasquez, Jennifer J Wenner, Candice J McNeil
In our correspondence, we describe the results from a quality improvement survey in a sexual health clinic in North Carolina regarding attitudes and perceptions among adolescents and providers regarding specimen self-collection. We find that adolescents have high levels of acceptability for self-collection and confidence in their ability to self-collection; however, providers expressed hesitation regarding
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Can laboratory HIV and infectious syphilis data inform future pre-exposure prophylaxis use in women in Ontario, Canada? Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-01-30 Yasamin Sadeghi, Paul Nelson, Ashleigh Sullivan, Vanessa Allen, Maan Hasso, Juan Liu, Vanessa Tran, Darrell H S Tan
Objectives Infectious syphilis has been proposed as an indication for HIV pre-exposure prophylaxis (PrEP) in women. We explored how many women experienced HIV seroconversion after being diagnosed with syphilis in Ontario between 20 April 2010 and 31 December 2021. Methods Through deterministic linkage of laboratory data at the Public Health Ontario laboratory, which conducts the vast majority of syphilis
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Seroconversion in syphilis screening without positive confirmatory tests points at early infection Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-01-22 Silvia Achia Nieuwenburg, Vita Willemijn Jongen, Maarten Schim van der Loeff, Henry de Vries, Alje van Dam
Introduction The chemiluminescence immunoassay (CLIA) is a widely used screening test for syphilis. A CLIA seroconversion in the absence of a positive line immunoassay (LIA) or rapid plasma reagin (RPR) could indicate either an early incubating syphilis or a false positive result. We aimed to evaluate the diagnostic value of such seroconversions. Methods We retrospectively analysed data of clients
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Time to treat the climate and nature crisis as one indivisible global health emergency Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-01 Chris Zielinski
Over 200 health journals call on the United Nations (UN), political leaders and health professionals to recognise that climate change and biodiversity loss are one indivisible crisis and must be tackled together to preserve health and avoid catastrophe. This overall environmental crisis is now so severe as to be a global health emergency. The world is currently responding to the climate crisis and
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Anorectal gonorrhoea and chlamydia among transgender women in Brazil: prevalence and assessment of performance and cost of anorectal infection detection and management approaches Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-01 Daniel Jason McCartney, Carla Gianna Luppi, Roberto José Carvalho Silva, Sandra de Araújo, Katia Cristina Bassichetto, Philippe Mayaud, Maria Amélia Veras
Objectives We aimed to determine the prevalence of anorectal Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) among transgender women in Brazil, and to assess the performance and costs of various approaches for the diagnosis and management of anorectal NG/CT. Methods TransOdara was a multicentric, cross-sectional STI prevalence study among 1317 transgender women conducted in five capital cities
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Implementation preferences for the management of sexually transmitted infections in the South African health system: a discrete choice experiment Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-01 Collins Iwuji, Catherine E Martin, Diantha Pillay, Patience Shamu, Susan Nzenze, Mercy Murire, Laura Ashleigh Cox, Alec Miners, Carrie Llewellyn, Saiqa Mullick
Objectives Despite strengthening HIV prevention with the introduction of pre-exposure prophylaxis (PrEP), STI services have remained relatively unchanged and the standard of care remains syndromic management. We used a discrete choice experiment to investigate service users’ preferences for the diagnosis and treatment of STIs in South Africa. Methods Between 1 March 2021 and 20 April 2021, a cross-sectional
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Factors associated with bacterial sexually transmitted infections among people of South Asian ethnicity in England Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-01 Rageshri Dhairyawan, Ammi Shah, Julia Bailey, Hamish Mohammed
Objectives Despite being the largest ethnic minority group in England, South Asians have historically had low levels of utilisation of sexual health services (SHS) and sexually transmitted infection (STI) diagnoses, although recent data suggests this may be changing. This study aimed to investigate factors associated with a bacterial STI diagnosis among South Asians attending SHS in England. Methods
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Antimicrobial susceptibility profile of Neisseria gonorrhoeae from patients attending a medical laboratory, Institut Pasteur de Madagascar between 2014 and 2020: phenotypical and genomic characterisation in a subset of Neisseria gonorrhoeae isolates Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-01 Lala Fanomezantsoa Rafetrarivony, Mamitina Alain Noah Rabenandrasana, Elisoa Ratsima Hariniaina, Frédérique Randrianirina, Anthony Marius Smith, Tania Crucitti
Objectives Antimicrobial-resistant Neisseria gonorrhoeae (NG) is a concern. Little is known about antimicrobial susceptibility profiles and associated genetic resistance mechanisms of NG in Madagascar. We report susceptibility data of NG isolates obtained by the medical laboratory (CBC) of the Institut Pasteur de Madagascar, Antananarivo, Madagascar, during 2014–2020. We present antimicrobial resistance
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Trends in Chlamydia trachomatis IgG seroprevalence in the general population of the Netherlands over 20 years Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-01 Zoïe Willemijn Alexiou, Fleur van Aar, Bernice Maria Hoenderboom, Servaas Antonie Morre, Janneke Cornelia Maria Heijne
Objectives To report sex and age-specific Chlamydia trachomatis (Ct) seroprevalence estimates in the general population of the Netherlands between 1996 and 2017 and identify risk factors associated with Ct seropositivity. Methods Participants (n=5158, aged 15–59 years) were included from three independent nationwide population-based serosurveillance studies in 1996, 2007 and 2017. Participants completed
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Post-exposure prophylaxis, STI testing and factors associated with follow-up attendance: a review of 4159 cases of acute post-sexual assault medical care Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-01 Daniel Kane, Andrea Holmes, Maeve Eogan
Background Sexual assault (SA) is a prevalent issue with enduring consequences. Post-SA medical care mainly focuses on injuries, sexually transmitted infection (STI) prevention and detection, as well as preventing unwanted pregnancies. Swift access to post-SA medical care is vital with sexual assault treatment units (SATUs) streamlining this care. The primary aim of our study is to report on post-SA
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Sexually transmitted infections diagnosed in individuals presenting for forensic and medical care following sexual assault Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-01 Vanita R Parekh, Sarah J Martin, Alexandra Tyson, Anna Brkic, Janine McMinn, Cassandra Beaumont, Francis J Bowden
Background People who report sexual assault express concerns regarding contracting sexually transmitted infection (STI); however, published literature regarding the risk of STI transmission in this context is sparse. Method We audited STI and blood-borne virus (BBV) testing at a forensic and medical sexual assault care service in the Australian Capital Territory between 2004 and 2022. Eligibility for
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Evaluating preanalytical sample storage parameters for nucleic acid-based detection of Neisseria gonorrhoeae Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-01 Janath A Fernando, Marcelina Krysiak, Jacqueline Prestedge, Francesca Azzato, Deborah A Williamson, Shivani Pasricha
Objectives To ensure accurate diagnosis of infectious diseases, preanalytical factors should be considered when assessing specimen quality and subsequent test result. Accordingly, we aimed to systematically assess the effect of storage time, temperature and buffer on the analytical sensitivity of detecting the sexually transmitted pathogen, Neisseria gonorrhoeae across multiple molecular diagnostic
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Anorectal Mpox in men who have sex with men associated with sexually transmitted co-infections: a case series Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-01 Annie Russell, Mohammed Siddiq, Colin Fitzpatrick, Daniel Richardson
Since May 2022, there has been an outbreak of Mpox in the UK, alongside Europe and the USA, mainly associated with sexual contact among men who have sex with men (MSM).1 The majority of individuals with Mpox experience mild or moderate genital, anorectal and systemic symptoms, followed by complete recovery.1 Overall, published data suggest that 11%–44% of patients present with anorectal symptoms.1–3
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Compliance with COVID-19 rules on intimate physical contact between households Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-01 Dee Menezes, Pam Sonnenberg, Malachi Willis, Catherine H Mercer, Kirstin Mitchell, Nigel Field
Despite concerns about COVID-19 ‘lockdown fatigue’ affecting compliance, most people adhered to the rules on intimate physical contact (ie, sex) between households. Four months after the first lockdown started, ~10% of survey participants in the Natsal-COVID wave 1 study reported sex outside the household in the 4 weeks prior to interview (quasi-representative web panel of 6654 British residents aged
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Epidemiology of syphilis among female sex workers and pregnant women during a period of increasing syphilis among women in Japan, 2019–2021 Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-01 Ayu Kasamatsu, Miyako Otsuka, Takuri Takahashi, Yuzo Arima, Takeshi Arashiro, Hanae Ito, Takuya Yamagishi, Yuki Ohama, Shu-ichi Nakayama, Yukihiro Akeda, Motoi Suzuki
Japan has been facing an unprecedented increase in syphilis, largely among women who have sex with men and men who have sex with women.1–3 Notifications among women have increased >15-fold over the past decade (figure 1A),1 2 and female sex worker (FSW) status has been found to be associated with incident syphilis.4 These epidemiological trends necessitate urgent action to prevent transmission and
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Correspondence on “A case for the inclusion of doxycycline post-exposure prophylaxis for sexually transmitted infections among men who have sex with men in sub-Saharan African countries’ guidelines for the management of sexually transmitted infections” by “Dzinamarira et al” Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-01 Tafadzwa Dzinamarira, Enos Moyo, Grant Murewanhema
Sexually transmitted infections (STIs) pose a significant public health challenge, particularly among men who have sex with men (MSM), since significantly they multiply the risk of HIV transmission. The risk of HIV infection among MSM is 28 times greater than that for other adult men. Doxycycline post-exposure prophylaxis (PEP) has emerged as a potential intervention to reduce the transmission of STIs
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Record high incidence of syphilis cases in Finland in 2022 Sex. Transm. Infect. (IF 3.6) Pub Date : 2024-02-01 Ilari Kuitunen
The incidence of sexually transmitted infections in Finland has continued to increase in recent decade and throughout the pandemic.1 2 Concerning development has been especially in Chlamydia trachomatis and Neisseria gonorrhoeae infections. The aim of this brief report was to report the incidence of laboratory-confirmed syphilis cases in Finland. For this nationwide cohort study, all cases of …
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Sexual Function and Well-being Special Interest Group: what is in a name? Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-12-01 Penny Goold,Kirstin Mitchell,Nadia Ahmed,Shalini Andrews,,
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Childhood sexual abuse, risk behaviours and chemsex engagement among men who have sex with men in Paris, France Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-11-28 Marc Shelly, Solène Bost, David Moreau
Drückler et al suggest that chemsex engagement among men who have sex with men (MSM) is significantly associated with reporting non-consensual sex.1 Inspired by clinical stories gathered in a sexual healthcare service, we investigated a possible relationship between childhood sexual abuse (CSA), that is, having been a victim of forced genital contact by an adult before age 13, and current chemsex engagement
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Hepatitis B and hepatitis C testing outcomes among service users of Sexual Health London: an online sexually transmitted infection testing service for London residents Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-11-24 Sara Louise Day, Gemma McDonald, Chris Kellett
Objectives The UK signed up to the 2016 global health strategy to eliminate viral hepatitis as a public health problem. Effective monitoring of hepatitis testing outcomes is required to track progress against targets. National reporting does not include hepatitis B and hepatitis C infections (HBV/HCV) detected by online sexually transmitted infection (STI) testing services (e-services). We identify
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Changes in prevalence of Mycoplasma genitalium macrolide and fluoroquinolone resistance: notes from a 13-year retrospective survey in Dalarna County, Sweden Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-12-01 Suhella Tulsiani Drud, Carin Anagrius, Britta Loré, Karin Elfving, Jørgen Skov Jensen
Objective Macrolide and fluoroquinolone resistance in Mycoplasma genitalium (MG) is of emerging global concern. Compared with neighbouring countries such as Denmark, Sweden has had lower rates of macrolide resistance while fluoroquinolone resistance rates are less well documented. This study retrospectively examined macrolide, fluoroquinolone and multidrug resistance rates from Dalarna County, Sweden
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Using infection prevalence, seroprevalence and case report data to estimate chlamydial infection incidence Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-12-01 Patrick A Clay, Emily D Pollock, Casey E Copen, E Gloria Anyalechi, Damien C Danavall, Jaeyoung Hong, Christine M Khosropour, Eboni Galloway, Ian H Spicknall
Objectives To measure the effectiveness of chlamydia control strategies, we must estimate infection incidence over time. Available data, including survey-based infection prevalence and case reports, have limitations as proxies for infection incidence. We therefore developed a novel method for estimating chlamydial incidence. Methods We linked a susceptible infectious mathematical model to serodynamics
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Impact of time of culture specimen collection on the recovery of Neisseria gonorrhoeae after a positive nucleic acid amplification test Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-12-01 Patricia Nadal-Barón, Jesús Trejo-Zahinos, Jorge Nestor García, Paula Salmerón, Elena Sulleiro, Maider Arando, Vicente Descalzo, Patricia Álvarez-Lopez, Rachid El Ouazzani, Luis López, Francesc Zarzuela, Edurne Ruiz, Montserrat Llinas, Albert Blanco-Grau, Adrian Curran, María Nieves Larrosa, Tomàs Pumarola, Yannick Hoyos-Mallecot
Objectives Culture of Neisseria gonorrhoeae remains essential for antimicrobial resistance (AMR) surveillance. We evaluated the effect of time of specimen collection on culture yield following a positive nucleic acid amplification test (NAAT). Methods We retrospectively assessed N. gonorrhoeae culture yield among asymptomatic individuals (largely men who have sex with men) who attended for sexual health
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Association between where men who have sex with men (MSM) meet sexual partners and chlamydia/gonorrhoea infection before and during the COVID-19 pandemic in San Diego, California Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-12-01 Colin M B King, Richard S Garfein, Angela R Bazzi, Susan J Little, Britt Skaathun
Background Meeting sex partners online is associated with increased risk of acquiring sexually transmitted infections. We examined whether different venues where men who have sex with men (MSM) meet sex partners was associated with prevalent Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection, and whether prevalence increased during (vs before) the COVID-19 pandemic. Methods We conducted
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Understanding experiences of potential harm among MSM (cis and trans) using HIV self-testing in the SELPHI randomised controlled trial in England and Wales: a mixed-methods study Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-12-01 T Charles Witzel, Emily Jay Nicholls, Leanne McCabe, Peter Weatherburn, Sheena McCormack, Christopher Bonell, Mitzy Gafos, Fiona C Lampe, Andrew Speakman, David Dunn, Denise Ward, Andrew N Phillips, Roger Pebody, Michelle M Gabriel, Yolanda Collaco-Moraes, Alison J Rodger, Fiona M Burns
Background The potential of HIV self-testing (HIVST) to cause harm is a concern hindering widespread implementation. The aim of this paper is to understand the relationship between HIVST and harm in SELPHI (An HIV Self-testing Public Health Intervention), the largest randomised trial of HIVST in a high-income country to date. Methods 10 111 cis and trans men who have sex with men (MSM) recruited online
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Egocentric sexual network analysis among gay and bisexual men who have sex with men with and without mpox infection Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-12-01 İbrahim Sönmez, Héctor Martínez Riveros, Cinta Folch, Clara Suñer, Yesika Díaz, Lucía Alonso, Cristina Agusti, Adrià Mendoza, Eloy José Tarín-Vicente, Xènia Oller, Andrea Alemany, Àngel Rivero, Eva Orviz, Ana Silva-Klug, Oriol Mitjà, Jordi Casabona
Objectives Recent outbreaks of the mpox (monkeypox) virus have been detected in dense sexual networks of gay and bisexual men who have sex with men (GBMSM). The objective of this study is to describe and compare the epidemiological and behavioural characteristics, as well as the sexual networks, of GBMSM diagnosed with mild mpox in Spain. Methods A prospective case–control study was conducted in Spain
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Retrospective testing for mpox virus in routine STI screens from men who have sex with men in England, August–October 2022 Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-12-01 Rachel Pitt-Kendall, Clare Foster, Michael Rayment, Beata Orzechowska, Rufat Mammadov, Suneeta Soni, Simon Mortlock, Jodie Owen, Luke Uglow, Michaela Joanne Day, Rupa Rai Gurung, Amber Savary-Trathen, Rhian Jenkins, Emma McGuire, Natalie Gordon, Sara Louise Day, Adrian M Kelly, Charlotte Goward, Kate Folkard, Hannah Charles, Hamish Mohammed, Colin S Brown, Helen Fifer
Objectives A global outbreak of mpox (monkeypox) has been ongoing since 2022, with most cases in the UK detected in gay, bisexual and other men who have sex with men (GBMSM). Asymptomatic and pauci-symptomatic mpox infection has been reported outside of the UK. We aimed to investigate whether mpox could be detected in specimens from GBMSM in England who were attending sexual health services (SHSs)
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High uptake of vaccination against mpox in men who have sex with men (MSM) on HIV pre-exposure prophylaxis (PrEP) in Paris, France Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-12-01 Romain Palich, Thibaut Jedrzejewski, Luminita Schneider, Naoual Qatib, Thibault Orriere, Daniel Gosset, Thomas Grunemwald, Dominique Pataut, Michel Ohayon, Christine Katlama
In July 2022, the French health authorities recommended smallpox vaccination (IMVANEX and JYNNEOS) to prevent mpox in population at high risk of exposure. HIV and pre-exposure prophylaxis (PrEP) physicians were informed and involved in the deployment of this vaccination, but there has been no communication to the general public. The current mpox epidemic in France, the rest of Europe and the USA is
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Differential uptake and effects of digital sexually transmitted and bloodborne infection testing interventions among equity-seeking groups: a scoping review Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-12-01 Ihoghosa Iyamu, Rodrigo Sierra-Rosales, Claudia S Estcourt, Amy Salmon, Mieke Koehoorn, Mark Gilbert
Background Digital sexually transmitted and bloodborne infection (STBBI) testing interventions have gained popularity. However, evidence of their health equity effects remains sparse. We conducted a review of the health equity effects of these interventions on uptake of STBBI testing and explored design and implementation factors contributing to reported effects. Methods We followed Arksey and O’Malley’s
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Timing of HPV vaccination as adjuvant treatment of CIN2+ recurrence in women undergoing surgical excision: a meta-analysis and meta-regression Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-12-01 Marek Petráš, Vladimír Dvořák, Danuše Lomozová, Roman Máčalík, Sylva Neradová, Pavel Dlouhý, Jana Malinová, Jozef Rosina, Ivana Králová Lesná
Objective The main aim was to determine the overall vaccine effectiveness (VE) against recurrent cervical intraepithelial neoplasia grade 2 or worse (CIN2+) including specific VE associated with timing of human papillomavirus (HPV) vaccination using data from published studies. Design Meta-analysis and meta-regression. Data sources A computerised literature search was undertaken using the MEDLINE,
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A case of chronic bacterial prostatitis due to Mycoplasma genitalium Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-12-01 Roberto Rossotti, Giovanna Travi, Nicholas Brian Bana, Carloandrea Orcese, Massimo Puoti
Mycoplasma genitalium (MG) is a common cause of non-gonococcal urethritis, but a role in acute or chronic prostatitis has not been described. We describe the case of a 42-year-old man with recurrent urinary tract infections since 2018 who developed chronic prostatitis despite several and prolonged antibiotic courses. Multiparametric prostatic magnetic resonance showed peripheral inflammatory alterations
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PrEP2U: a novel community partnership HIV pre-exposure prophylaxis clinic Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-12-01 Jim Abi Frem, Annie Russell, Kayleigh Nichols, Leonardo Buonsenno, Marc Tweed, Colin Fitzpatrick, Mary Darking, Jennifer Whetham, Daniel Richardson
Broadening the access of HIV–pre-exposure prophylaxis (HIV-PrEP) prevents HIV transmission.1 In Brighton, we partnership with The Terrence Higgins Trust to deliver a community-based HIV-PrEP service (PrEP2U).2 PrEP2U operates weekly, offering comprehensive STI/HIV testing, HIV-PrEP monitoring and hepatitis A & B and human papilloma virus vaccinations. We aimed to explore whether …
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HIV-1 DNA drug resistance testing to guide successful suppression of low-level viraemia: a case report Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-12-01 Bianchuan Cao, Mei Liu, Rui Zhu, Tianru Yuan, A’shamu E’er, Shaofang Song, Tong Wang, Li Zhong
A treatment-naïve 10-year-old female patient living with HIV-1 infection started antiretroviral therapy (ART) in April 2018 with zidovudine+lamivudine+nevirapine, which was changed 19 months later to zidovudine+lamivudine+efavirenz. The HIV-1 RNA load ranged between 55 and 420 copies/mL between February 2020 and May 2021, and was 485 copies/mL in January 2022. At this time, the total HIV-1 DNA load
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High prevalence and incidence of gonorrhoea and chlamydia in young women eligible for HIV pre-exposure prophylaxis in South Africa and Zimbabwe: results from the HPTN 082 trial Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-11-01 Sinead Delany-Moretlwe, Nyaradzo Mgodi, Linda-Gail Bekker, Jared M Baeten, Chuwen Li, Deborah Donnell, Yaw Agyei, Denni Lennon, Scott M Rose, Marcia Mokgatle, Sheetal Kassim, Shorai Mukaka, Adeola Adeyeye, Connie Celum
Introduction We investigated the prevalence, incidence and factors associated with sexually transmitted infections (STIs) among young African women seeking HIV pre-exposure prophylaxis (PrEP). Methods HPTN 082 was a prospective, open-label PrEP study enrolling HIV-negative sexually active women aged 16–25 years in Cape Town and Johannesburg, South Africa, and Harare, Zimbabwe. Endocervical swabs from
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Hepatitis C testing among three distinct groups of gay, bisexual and other men who have sex with men: a cross-sectional study in the Celtic nations Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-11-01 David Whiteley, Dimitra Strongylou, Sally Brown, Peter Vickerman, Jamie Scott Frankis
Objective The hepatitis C virus (HCV) epidemic among gay, bisexual and other men who have sex with men (GBMSM) is associated with sexual and drug-related behaviours. To stem the tide of HCV infection in GBMSM, regular testing leading to early diagnosis and treatment as prevention is vital. This study aimed to evaluate the success of current HCV testing guidelines from the perspective of GBMSM in four
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Effect of COVID-19 pandemic restrictions on chlamydia and gonorrhoea notifications and testing in Queensland, Australia: an interrupted time series analysis Sex. Transm. Infect. (IF 3.6) Pub Date : 2023-11-01 Marguerite Dalmau, Robert Ware, Emma Field, Emma Sanguineti, Damin Si, Stephen Lambert
Objective To investigate trends in testing and notifications of chlamydia and gonorrhoea during the COVID-19 pandemic in Queensland, Australia. Methods Statewide disease notification and testing data between 1 January 2015 and 31 December 2021 were modelled using interrupted time series. A segmented regression model estimated the pre-pandemic trend and observed effect of the COVID-19 pandemic response