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Presence of anti-RBC antibodies correlates with parasitaemia and once-infected RBCs but not the extent of post-malaria haemolysis J. Travel Med. (IF 25.7) Pub Date : 2024-03-12 Pinkus Tober-Lau, Anna Karolina Kneller, Tilman Lingscheid, Beate Mayer, Thomas Zoller, Florian Kurth
In a cohort of patients treated with oral artemisinin combination therapy (ACT) for uncomplicated malaria, the presence of anti-RBC auto-antibodies does not correlate with the extent of post-treatment haemolysis. Patients with positive antibody screening test on d14 had higher initial parasitaemia and a higher number of once-infected RBCs throughout follow-up.
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The impact of the cruise ship coral princess on COVID-19 transmission in regional Western Australia in 2022 J. Travel Med. (IF 25.7) Pub Date : 2024-03-12 Ashley L Quigley, Mohana Kunasekaran, Haley Stone, Damian Honeyman, Adriana Notaras, Samsung Lim, C Raina MacIntyre
Increased COVID-19 community transmission in regional areas with high Aboriginal populations, limited health infrastructure and low vaccination rates, could result in clusters of transmission with increased deaths rates. Pilbara, a regional community with a high Aboriginal population, showed a 34.8% increase in COVID-19 cases in the four-weeks post cruise-ship docking.
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Hydatid cyst in the gluteal muscle - an unusual location J. Travel Med. (IF 25.7) Pub Date : 2024-03-08 Maria Ana Quadros Flores, Hugo Vasques, Diogo Mendes Pedro
Echinococcus sp. is an intestinal parasite of canids and felids, that can infect humans after contaminated ingestion. Through the portal circulation, the eggs can metastasize to the liver, lungs and, more infrequently, other organs. We present a hydatid cyst located on the gluteus muscles, a very unusual location.
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Escalating climate-related health risks for Hajj pilgrims to Mecca J. Travel Med. (IF 25.7) Pub Date : 2024-03-08 Saber Yezli, Salleh Ehaideb, Yara Yassin, Badriah Alotaibi, Abderrezak Bouchama
Background Global temperatures are on the rise, leading to more frequent and severe heatwaves with associated health risks. Heat-related illnesses are an increasing threat for travellers to hot climate destinations. This study was designed to elucidate the interplay between increasing ambient temperatures, incidence of heat-related illnesses, and the effectiveness of mitigation strategies during the
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Diagnostic challenges of recurrent malaria in non-endemic areas J. Travel Med. (IF 25.7) Pub Date : 2024-03-08 Maria F Ramirez-Hidalgo, Eric López González, Silvia Iglesias Moles, Cristina Acosta García, Jose Miguel Rubio Muñoz, Ricard López Ortega, Laura Gros Navés, Albert Bernet Sánchez, Alfredo Jover-Sáenz
In Spain, a patient’s unexpected relapse with P. falciparum raises questions about genetic influences on treatment efficacy. Meanwhile, in a separate case, a recurrence of P. malariae prompts speculation on latent reservoirs and treatment strategies. Delve into these complex cases that underscore the evolving landscape of malaria.
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Dihydroartemisinin-piperaquine treatment failure of uncomplicated plasmodium falciparum malaria infection in a traveller J. Travel Med. (IF 25.7) Pub Date : 2024-03-06 Océane Delandre, Nadim Shams Cassir, Nicolas Taudon, Joel Mosnier, Isabelle Fonta, Nicolas Benoit, Remy Amalvict, Cyril Linard, Marie Jumpertz, Coralie L’Ollivier, Hervé Bogreau, Bruno Pradines, Emilie Javelle
We report a late dihydroartemisinin-piperaquine treatment failure of uncomplicated Plasmodium falciparum malaria infection in a traveller without evidence of drug resistance. The correct treatment intake was confirmed, isolates drugs susceptibility was confirmed by RSA-PSA and chemosusceptibility. No molecular markers associated with resistance to artemisinin derivatives or piperaquine were identified
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Wastewater-based epidemiological surveillance of SARS-CoV-2 new variants BA.2.86 and offspring JN.1 in south and Southeast Asia J. Travel Med. (IF 25.7) Pub Date : 2024-03-05 Dhammika Leshan Wannigama, Mohan Amarasiri, Phatthranit Phattharapornjaroen, Cameron Hurst, Charin Modchang, Sudarat Chadsuthi, Suparinthon Anupong, Kazuhiko Miyanaga, Longzhu Cui, W K C P Werawatte, S M Ali Hosseini Rad, Stefan Fernandez, Angkana T Huang, Porames Vatanaprasan, Thammakorn Saethang, Sirirat Luk-in, Robin James Storer, Puey Ounjai, Ratana Tacharoenmuang, Naveen Kumar Devanga Ragupathi
Discover the shifting landscape of SARS-CoV-2 variants from October to December 2023, with JN.1 dominating South and Southeast Asia wastewater samples, increasing from < 10% to over 90%. Experience the dynamic evolution of viral strains in this period.
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Humoral immunogenicity of primary yellow fever vaccination in infants and children: a systematic review, meta-analysis, and meta-regression J. Travel Med. (IF 25.7) Pub Date : 2024-03-05 Pietro Ferrara, Lorenzo Losa, Lorenzo G Mantovani, Juan Ambrosioni, Fernando Agüero
Background Vaccination plays a critical role in mitigating the burden associated with yellow fever (YF). However, there is a lack of comprehensive evidence on the humoral response to primary vaccination in the paediatric population, with several questions debated, including the response when the vaccine is administered at early ages, the effect of co-administration with other vaccines, the duration
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Medical tourism and medical tourists: providing a sustainable course to integrating health treatments with tourism J. Travel Med. (IF 25.7) Pub Date : 2024-03-03 Glenn McCartney, Chu Feng Wang
Medical tourism (MT) is an expanding multidisciplinary economic activity that combines the healthcare and tourist industries, with patients increasingly travelling worldwide for medical treatments. MT provides economic benefits to destinations while raising ethical, quality, informed, and risk concerns for medical tourists. Greater cross-disciplinary studies and collaboration across sectors are advocated
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Usefulness of serial testing for the diagnosis of malaria in cases of fever upon return from travel J. Travel Med. (IF 25.7) Pub Date : 2024-03-03 Slack Lydia, Genton Blaise
Background When malaria is suspected in case of fever after travel in endemic areas, the current recommendation is to repeat the malaria test at 24-hour intervals, with up to two additional tests, as long as the test result is negative. A retrospective analysis was conducted to investigate the appropriateness of this recommendation by determining the proportion of tests with negative result at first
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The immune status of migrant populations in Europe and implications for vaccine-preventable disease control: a systematic review and meta-analysis J. Travel Med. (IF 25.7) Pub Date : 2024-02-26 Zeinab Cherri, Karen Lau, Laura B Nellums, Jan Himmels, Anna Deal, Emma McGuire, Sandra Mounier-Jack, Marie Norredam, Alison Crawshaw, Jessica Carter, Farah Seedat, Nuria Sanchez Clemente, Oumnia Bouaddi, Jon S Friedland, Michael Edelstein, Sally Hargreaves
Background Ensuring vaccination coverage reaches established herd immunity thresholds (HIT) is the cornerstone of any vaccination programme. Diverse migrant populations in European countries have been associated with cases of vaccine-preventable diseases (VPD) and outbreaks, yet it is not clear to what extent they are an under-immunised group. Methods We did a systematic review and meta-analysis to
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Visa relaxation policies and Potential implications on public health in Africa J. Travel Med. (IF 25.7) Pub Date : 2024-02-21 Allan Komakech, Karl Angendu Baki, Jonathan Izudi
In this article, we explore how Africa’s visa relaxation policies could transform public health landscapes, with the potential of increasing access to healthcare and collaborative disease control, while also posing challenges in managing infectious disease spread amidst already porous borders. We also suggest recommendations to some of the challenges.
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Assessing viral metagenomics for the diagnosis of acute undifferentiated fever in returned travellers: a multicenter cohort study J. Travel Med. (IF 25.7) Pub Date : 2024-02-21 Daniel Camprubí-Ferrer, Alexandru Tomazatos, Leire Balerdi-Sarasola, Ludovico G Cobuccio, Steven Van Den Broucke, Balázs Horváth, Marjan Van Esbroeck, Miguel J Martinez, Javier Gandasegui, Carme Subirà, Meritxell Saloni, Blaise Genton, Emmanuel Bottieau, Dániel Cadar, Jose Muñoz
Background Up to 45% of febrile returning travellers remain undiagnosed after a thorough diagnostic work-up, even at referral centers. Although metagenomic next-generation sequencing (mNGS) has emerged as a promising tool, evidence of its usefulness in imported fever is very limited. Methods Travellers returning with fever were prospectively recruited in three referral clinics from November 2017 to
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Hospital-acquired malaria in Catalonia: an unexpected post-surgical complication J. Travel Med. (IF 25.7) Pub Date : 2024-02-16 Javier Díez de los Ríos, María Navarro, Anna Vilamala, José Miguel Rubio, Ingrid Vilaró, Anna Besolí, Judit Serra-Pladevall
Hospital-acquired malaria represents a challenge with sporadic cases of non-imported malaria in several European countries. We present a case of nosocomial malaria in a hospital located in Catalonia, illustrating the possibility of horizontal patient-to-patient transmission of malaria in a hospital setting, with the exact manner of transmission difficult to determine.
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Cyclones and flooding in tropical northern Australia increase the risk of exposure to melioidosis J. Travel Med. (IF 25.7) Pub Date : 2024-02-15 Irmgard L Bauer
Due to two recent cyclones in North Queensland, leading to widespread flooding, working holiday visa holders, typically backpackers, are now permitted to assist in cleanup efforts. Melioidosis, endemic in tropical Northern Australia, is a rare but potentially fatal bacterial infection. Travel health advice for backpackers to Australia should include appropriate information.
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Lack of a non-specific protective effect of prior yellow fever vaccination against COVID-19 J. Travel Med. (IF 25.7) Pub Date : 2024-02-14 Miguel Martínez-Lacalzada, Angeline Cruz, Carme Subirà, Isabel Vera, Montserrat Roldan, Teresa De Alba, Meritxell Saloni, Jose Muñoz, Natalia Rodríguez-Valero
Live-attenuated virus vaccines, such as yellow fever vaccine, exhibit non-specific immunomodulatory effects, prompting exploration of their potential impact on COVID-19 pandemic. In this retrospective study, we didn’t observe an association between prior yellow fever vaccination with SARS-CoV-2 infection incidence. In the multivariate model, no association was found with COVID-19 prognosis.
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A decalogue for personalized travel health assistance with AI-driven chatbots J. Travel Med. (IF 25.7) Pub Date : 2024-02-09 Francesco Baglivo, Luigi De Angelis, Gianluca Cruschelli, Caterina Rizzo
This article delves into the innovative integration of AI-driven chatbots in travel medicine, proposing a decalogue for creating effective, personalized health assistance tools with a practical example (a custom GPT, with OpenAI GPT-4).
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Travel health practices, behaviours and experiences of people living with type 1 diabetes J. Travel Med. (IF 25.7) Pub Date : 2024-02-09 Chloe Tarlton, Steven James, Barnaby Dixson, Judy Craft
Introduction There is limited data regarding the international travel history and preparation, as well as glycaemic control practices, risk behaviours, and experiences of people with type 1 diabetes during travel. Our review aimed to address the research question: ‘What are the health practices, behaviours, and experiences of people with type 1 diabetes when travelling?’ Methods We conducted a mixed-methods
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Delayed care-seeking in international migrant workers with imported malaria in China J. Travel Med. (IF 25.7) Pub Date : 2024-02-09 Jiyue Gu, Yuanyuan Cao, Liying Chai, Enyu Xu, Kaixuan Liu, Zeyin Chong, Yuying Zhang, Dandan Zou, Yuhui Xu, Jian Wang, Olaf Müller, Jun Cao, Guoding Zhu, Guangyu Lu
Background Imported malaria cases continue to pose major challenges in China as well as in other countries that have achieved elimination. Early diagnosis and treatment of each imported malaria case is the key to successfully maintaining malaria elimination success. This study aimed to build an easy-to-use predictive nomogram to predict and intervene against delayed care seeking among international
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Seroprevalence of dengue, Japanese encephalitis, and Zika among long-term expatriates in Thailand J. Travel Med. (IF 25.7) Pub Date : 2024-02-09 Amornphat Kitro, Hisham Ahmed Imad, Phimphan Pisutsan, Wasin Matsee, Wachiranun Sirikul, Ratana Sapbamrer, Erica Rapheal, Stefan Fernandez, Thomas S Cotrone, Aaron R Farmer, Taweewun Hunsawong, Udomsak Silachamroon, Lapakorn Chatapat, Jutarmas Olanwijitwong, Parichat Salee, Kathryn B Anderson, Watcharapong Piyaphanee
Background Travel to Southeast Asia increases the likelihood of acquiring mosquito-borne Flavivirus infections such as dengue (DENV), Japanese encephalitis (JEV), and Zika viruses (ZIKV). Expatriates are long-term travellers who have a higher risk of mosquito-borne illness at their destination country. The purpose of this study was to evaluate the seroprevalence of DENV, JEV and ZIKV infections and
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Sexual and reproductive health integration into pre-travel consultations: a scoping review J. Travel Med. (IF 25.7) Pub Date : 2024-02-09 Carlos Santoalaya, Juhi Malhotra, James A Fowler, Sarah Warzywoda, Joe Debattista, Deborah J Mills, Colleen Lau, Luis Furuya-Kanamori, Jo Durham, Amy B Mullens, Satrio Nindyo Istiko, Judith A Dean
Background Casual sex during travel is a major preventable factor in the global transmission of sexually transmissible infections (STI). Pre-travel consults present an excellent opportunity for practitioners to educate travellers about sexual and reproductive health (SRH) and safety. The scoping review aims to explore and understand the extent to which SRH is included in pre-travel consultations. Methods
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Think TB! A rare case of influenza and rapid progressive Neurotuberculosis coinfection J. Travel Med. (IF 25.7) Pub Date : 2024-02-08 J Schroeder, A Schlesinger, L Burghaus, P Pape, M Balke
An Indian migrant presented with increasing neurological symptoms after an acute influenza B infection. We diagnosed progressive neurotuberculosis—a rare and difficult case of tuberculosis and influenza co-infection. It highlights the importance of broad-based diagnostics in people from low- and middle-income countries, taking into account unusual manifestations of tuberculosis.
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Traveller studies in low- and middle-income countries: a critical gap in global antibiotic resistance surveillance J. Travel Med. (IF 25.7) Pub Date : 2024-02-02 Jay Graham, Nam Nguyen, Dania Hussain, Maya L Nadimpalli
A substantial proportion of global travel occurs between low- and middle-income countries (LMICs) for the purposes of migration, medical tourism, trade, and employment, and this is likely to accelerate due to climate change-related migration. Traveller studies based in LMICs are needed to better monitor the global spread of antibiotic resistance.
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Leveraging community advisory boards within travel medicine to help reduce malaria incidence in refugees, immigrants and migrants visiting friends and relatives abroad: reflections from the Minnesota malaria community advisory board on patient-provider interactions J. Travel Med. (IF 25.7) Pub Date : 2024-02-02 Joseline Haizel-Cobbina, Ama Eli Boumi, Erica Chung, James Sobboh, Jonathan M Rose, Esther Mwangi, Rebecca Johnson, Richard B Oni, Danushka Wanduragala, William M Stauffer III
Refugees, immigrants and migrants often have barriers to travel medicine. Community Advisory Boards (CAB) are a vital but underutilized tool for understanding and meeting healthcare needs and challenges, providing communities with a voice, and finding solutions. The paper discusses a malaria prevention community-based participatory research project informed by a CAB.
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The earliest description of possible viral haemorrhagic fever and epistaxis identified in ancient Greece J. Travel Med. (IF 25.7) Pub Date : 2024-01-24 Hutan Ashrafian
Viral haemorrhagic fever is a syndrome characterized by fever and hemorrhagic manifestations, where examples are located in specific geographic regions, based on factors including reservoirs, vectors, and climate. Here I present the first description of possible viral hemorrhagic fever with corresponding characteristics and likely neuropsychiatric involvement in Ancient Greece.
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The epidemiology of imported and locally-acquired dengue in Australia, 2012–2022 J. Travel Med. (IF 25.7) Pub Date : 2024-01-18 Asma Sohail, Katherine L Anders, Sarah L McGuinness, Karin Leder
Background Dengue is the most important arboviral disease globally, and poses ongoing challenges for control including in non-endemic countries with competent mosquito vectors at risk of local transmission through imported cases. We examined recent epidemiological trends in imported and locally-acquired dengue in Australia, where the Wolbachia mosquito population replacement method was implemented
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Substantial discrepancies in dengue case estimates between the global burden of disease study and Taiwan Centers for disease control J. Travel Med. (IF 25.7) Pub Date : 2024-01-18 Sin Yee Lee, Hsin-I Shih, Chwan-Chuen King, Tsung-Hsueh Lu, Yu-Wen Chien
Taiwan’s dengue cases vary annually, peaking in infrequent epidemics, which differ substantially from the Global Burden of Disease Study’s (GBD’s) projections. Although the GBD study provides invaluable insights into global health trends, its modelling approach fails to capture the dynamic change of dengue transmission.
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Detection of imported clinical strain of bla NDM-1-harbouring ST147 Klebsiella pneumoniae from a Ukrainian immigrant J. Travel Med. (IF 25.7) Pub Date : 2024-01-18 Shinnosuke Fukushima, Hideharu Hagiya, Kazuyoshi Gotoh, Shuma Tsuji, Koji Iio, Osamu Matsushita
We have isolated a blaNDM-1-harbouring ST147 Klebsiella pneumoniae strain from a Ukrainian immigrant hospitalized at a Japanese hospital, which was genetically corroborated to be highly identical to a Russian-derived isolate. This case highlights that the geopolitical risk potentially increases the global dissemination of antimicrobial resistance pathogens.
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Recreational substance use among international travellers J. Travel Med. (IF 25.7) Pub Date : 2024-01-17 Sakarn Charoensakulchai, Manasvin Onwan, Sukrit Kanchanasurakit, Gerard Flaherty, Wasin Matsee
Background Drug tourism reflects the expanding illicit drug market, posing health risks in unfamiliar travel settings. Existing knowledge specifically addressing substance use among international travellers is sparse and has not been reviewed to date. This review aimed to describe the recreational substance abuse in international travellers. Methods A literature search was conducted on PubMed, Google
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From GeoSentinel data to epidemiological insights: a multidisciplinary effort towards artificial intelligence-supported detection of infectious disease outbreaks J. Travel Med. (IF 25.7) Pub Date : 2024-01-17 Stan Heidema, Ivo V Stoepker, Gerard Flaherty, Kristina M Angelo, Richard A J Post, Charles Miller, Michael Libman, Davidson H Hamer, Edwin R van den Heuvel, Ralph Huits
The growing complexity of GeoSentinel surveillance data creates opportunities for novel data science-based outbreak detection methods. Challenges may be overcome by effective multidisciplinary collaboration. The early signals generated by outbreak detection methods using GeoSentinel data may influence policymaking, shape public health responses, and contribute to global disease control strategies.
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Incidence and risk factors for travellers’ diarrhoea among short-term international adult travellers from high-income countries: a systematic review with meta-analysis of cohort studies J. Travel Med. (IF 25.7) Pub Date : 2024-01-15 Siobhan C Carroll, Maria Eugenia Castellanos, Robyn A Stevenson, Lars Henning
Background Travellers’ Diarrhoea (TD) continues to be the most common travel-related medical event in international travellers. Updated incidence and risk factor data will improve pre-travel medical advice for travellers from high-income countries (HIC), providing an opportunity for disease prevention, and appropriate disease management. Methods A systematic search for cohort studies of TD incidence
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Improving health literacy of passengers of cruise ships: readability of passenger-facing COVID-19 information provided by commercial cruise lines—an infodemiology study J. Travel Med. (IF 25.7) Pub Date : 2024-01-11 John E Moore, Beverley C Millar
Readability of COVID-19 information from 35 cruise lines was examined. Mean Flesch Reading Ease and Flesch–Kincaid Grade Level scores (±standard error of mean) were 46.6 ± 1.3 (target ≥60) and 10.9 ± 0.3 (target ≤ 8.0), respectively. Two (6%) cruise lines met readability reference targets. Readability tools may aid in preparing more easily read passenger-facing health-related information on existing
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Rationale for Japanese encephalitis vaccination in short-term travellers to endemic areas J. Travel Med. (IF 25.7) Pub Date : 2024-01-10 Sakarn Charoensakulchai, Pattaratida Singhasenee, Wasin Matsee, Eric Caumes, Phimphan Pisutsan
Although the Japanese encephalitis (JE) vaccine is typically strongly recommended for long-term high-risk travellers, some cases of JE infections have been reported among short-term travellers with seemingly low risk. This article underscores the advantages and reasoning behind JE vaccination for this particular group of travellers.
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WHO Strategic Advisory Group of Experts on Immunization Recommendations for use of a Novel Pentavalent Meningococcal ACWXY Vaccine: A Critical Step towards Ending Meningococcal Epidemics in Africa J. Travel Med. (IF 25.7) Pub Date : 2024-01-10 Lucy A McNamara, John Neatherlin
A new pentavalent meningococcal ACWXY vaccine is poised to have a dramatic impact on the burden of meningococcal disease in the meningitis belt of Africa. Implementation of this vaccine is a critical step towards the first visionary goal of WHO's roadmap to defeat meningitis by 2030: eliminating bacterial meningitis epidemics.
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Piloting delivery of PfSPZ vaccines for malaria through a cryogenic vaccine cold chain to travel and military medicine clinics J. Travel Med. (IF 25.7) Pub Date : 2024-01-10 Eric R James, L W Preston Church, Stephen L Hoffman, Brian D Robertson, Patrick W Hickey, C O L David J Schwartz, P O2 Patrick T Logan, Theresa D Asare, Macie L Jones, L T C Jeannie L Bay, Austin K Roschel, Jacqueline L Pfeiffer, Rebecca W Acosta, Ethan Schiavi, Alberto M Acosta, Mark Noble, Thomas Henkel, Cebrina Young
Background PfSPZ vaccines comprising Plasmodium falciparum (Pf) sporozoites (SPZ) have demonstrated > 90% protection against variant Pf malaria infections for at least 12 weeks; they are the only vaccines with the level of efficacy necessary to protect travellers. PfSPZ are eukaryotic cells stabilized by cryopreservation and distributed using a cryogenic (below −150°C) cold chain. The Ebola vaccine
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Anaphylaxis onboard commercial aircraft: what can we learn from post event safety reports? J. Travel Med. (IF 25.7) Pub Date : 2024-01-05 Karan Singh Ghatora, Mark Karlsson Cairns
This letter details a review of safety reports submitted to the UK Civil Aviation Authority over a 5 year period relating to severe allergic reactions. No trend of seasonality and evidence of aerosolisation was found. Reports were 4.8 times more likely to be submitted on an inbound flight than an outbound flight.
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Q fever: a rare zoonotic disease as a cause of pneumonia in travellers J. Travel Med. (IF 25.7) Pub Date : 2024-01-05 Tamara Nordmann, Dorothea Wiemer, Matthias Halfter, Andrea Vanegas Ramirez, Dennis Tappe, Sabine Jordan, Michael Ramharter, Johannes Jochum
Q fever occurs worldwide but it is rarely reported in travellers. Diagnosing Q fever pneumonia can be challenging and may solely rely on clinical or radiological findings until confirmation by seroconversion can be obtained. We describe a traveller from Brazil demonstrating distinct clinical and radiological characteristics of Q fever pneumonia.
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Failure of artemether-lumefantrine therapy in travellers returning to Belgium with plasmodium falciparum malaria: an observational case series with genomic analysis J. Travel Med. (IF 25.7) Pub Date : 2023-12-29 Jan Pierreux, Emmanuel Bottieau, Eric Florence, Ula Maniewski, Anne Bruggemans, Jiska Malotaux, Charlotte Martin, Janneke Cox, Deborah Konopnicki, Pieter Guetens, Jacob Verschueren, Jasmine Coppens, Marjan Van Esbroeck, Mathijs Mutsaers, Anna Rosanas-Urgell
Background Failure of artemisinin-based combination therapy (ACT) is increasingly reported in patients with Plasmodium falciparum malaria in sub-Saharan Africa. We aimed to describe the clinical and genomic characteristics of recent cases of P. falciparum malaria failing artemether-lumefantrine in Belgium. Methods Travel-related cases of malaria confirmed at the national reference laboratory of the
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Yellow fever vaccine-associated neurologic and viscerotropic disease: a 10-year case series of the French National Reference Center for arboviruses with clinical and immunological insights J. Travel Med. (IF 25.7) Pub Date : 2023-12-21 Anne Le Hir, Guillaume A Durand, José Boucraut, Annabelle Garnier, Marie Mura, Sylvain Diamantis, Michel Carles, Claire Durand, Cyril Schweitzer, Claire Audouard, Véronique Decroix, Romain Boyez, Anne Van Dendriessche, Alexandre Leclancher, Elsa Kaphan, Luce Barbat du Closel, Renaud Verdon, Damien du Cheyron, Astrid Vabret, Delphine Vergnon, Gilda Grard, Rémi Charrel, Xavier de Lamballerie, Carole
Background Immunization against the Yellow fever virus (YFV) with the 17D live-attenuated vaccine is the most effective way to prevent the disease. However, unexpected severe adverse events can occur. They consist in a neurological disease (YEL-AND), a viscerotropic disease (YEL-AVD), or anaphylaxis. In this article, we describe the epidemiology, clinical and biological features of YEL-AND and YEL-AVD
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Severe leptospirosis with rhabdomyolysis in a traveller visiting Thailand J. Travel Med. (IF 25.7) Pub Date : 2023-12-21 Anastasia Putri, Rachata Charoenwisedsil, Narissara Techavachara, Hisham Imad, Sutatip Chinpraditsuk, Janjira Thaipadungpanit, Wasin Matsee
We present a case of leptospirosis in a 32-year-old German who exhibited a progressing fever, calf pain complicated with acute kidney injury, and rhabdomyolysis following engagement in freshwater activities at a waterfall in Thailand. Fortunately, the patient made a full recovery without the need for renal replacement therapy.
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International travel increases risk of urinary tract infection caused by extended-spectrum beta-lactamase-producing Enterobacterales—three-arm case–control study J. Travel Med. (IF 25.7) Pub Date : 2023-12-19 Anu Patjas, Antti Martelius, Jukka Ollgren, Anu Kantele
Background Extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-PE) have worldwide become increasingly prevalent as pathogens causing urinary tract infections (UTIs), posing challenges in their treatment. Of particular concern are travellers to low- and middle-income countries (LMICs), a substantial proportion of whom become colonised by ESBL-PE, with UTIs as the most common clinical manifestation
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Out of Africa: increasing reports of artemether-lumefantrine treatment failures of uncomplicated plasmodium falciparum infection J. Travel Med. (IF 25.7) Pub Date : 2023-12-16 Eric S Halsey, Mateusz M Plucinski
Studies of travellers returning from Africa with uncomplicated Plasmodium falciparum infection are starting to provide signals of failure of artemether-lumefantrine, a first-line treatment of uncomplicated malaria. Traveller-based reports offer an important adjunct to antimalarial efficacy studies performed in endemic regions.
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Rebound and steep increase of international travel after the COVID-19 pandemic: where are we going from here? J. Travel Med. (IF 25.7) Pub Date : 2023-12-15 Alexia Anagnostopoulos, Jan Fehr
The COVID-19 pandemic caused an unprecedented drop in air travel. Recovery was influenced by infection waves and different infection control measures. International travel entered a rebound phase in 2022, with more growth forecasted. Now it seems the time to reframe tourism linked to flights and considering planetary health aspects.
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A randomized, double-blinded phase 3 study to demonstrate lot-to-lot consistency and to confirm immunogenicity and safety of the live-attenuated chikungunya virus vaccine candidate VLA1553 in healthy adults J. Travel Med. (IF 25.7) Pub Date : 2023-12-13 Robert McMahon, Ulrike Fuchs, Martina Schneider, Sandra Hadl, Romana Hochreiter, Annegret Bitzer, Karin Kosulin, Michael Koren, Robert Mader, Oliver Zoihsl, Nina Wressnigg, Katrin Dubischar, Vera Buerger, Susanne Eder-Lingelbach, Juan Carlos Jaramillo
Background The global spread of the chikungunya virus (CHIKV) increases the exposure risk for individuals travelling to or living in endemic areas. This phase 3 study was designed to demonstrate manufacturing consistency between three lots of the single shot live-attenuated CHIKV vaccine VLA1553 and to confirm the promising immunogenicity and safety data obtained in previous trials. Methods This randomized
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Incidence of Anaphylaxis to YF-VAX® Yellow Fever Vaccination: A Retrospective Evaluation of Vaccine Adverse Event Reports 1999-2018. J. Travel Med. (IF 25.7) Pub Date : 2023-12-04 Bruce M McClenathan, Jillian N Taylor, Laurie A Housel, Margaret Ryan
Background The incidence of anaphylaxis after receipt of yellow fever (YF) vaccine is highly variable based upon previously published reports. Anaphylaxis after receiving the YF vaccine has been reported to range from 0 up to 22 per 1,000,000 doses. Our clinical experience suggested increased incidence, which prompted our investigation. We sought to evaluate the current incidence rate of anaphylaxis
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Learning to safely integrate generative artificial intelligence technology into travel medicine practice J. Travel Med. (IF 25.7) Pub Date : 2023-11-28 Gerard Thomas Flaherty
We have entered an exciting era where generative artificial intelligence is finding multiple applications in everyday life and scientific inquiry. This editorial explores the possibility of integrating this technology into the pre-travel consultation, but with careful consideration of its current capabilities, limitations, and potential risks to patient safety.
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Incidence and Influencing Factors of Psychological Problems among International Travelers During Quarantine. J. Travel Med. (IF 25.7) Pub Date : 2023-11-25 Simon Boyd,Wasin Matsee,Phimphan Pisutsan,Supitcha Kamolrattanakul,Watcharapong Piyaphanee
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Locally acquired Mpox outbreak in Riyadh, Saudi Arabia: clinical presentation, risk factors, and preventive measures. J. Travel Med. (IF 25.7) Pub Date : 2023-11-25 Nadeem Gul Dar,Sarah H Alfaraj,Khulood Naser Alboqmy,Hala Amer,Nazia Khanum,Faleh Alshakrah,Hassan Abdallah,Deva Kumar,Shaimaa Hamdan Alzarzour,Nojoom Ahmed Alzahrani,Jasser Yahia Arishy,Suhair Ali Ahmed,Vicenta Escorpion,Edna Lopez,Sami Jedeba,Ziad A Memish
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Three novel pentavalent meningococcal vaccines J. Travel Med. (IF 25.7) Pub Date : 2023-11-25 Robert Steffen, Eric Caumes
Highlight Invasive meningococcal disease (IMD) is rare in travellers but associated with high mortality and long-term sequelae. Six serogroups (MenABCWXY) account for more than 90% of IMD. Three pentavalent vaccines are on the horizon: two MenABCWY, both with a 0–6 months schedule highly immunogenic and well tolerated, and one single-dose MenACWXY.
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Cat-transmitted human sporotrichosis in a non-endemic region in Brazil J. Travel Med. (IF 25.7) Pub Date : 2023-11-23 Paulo Ricardo Martins-Filho, Taise Ferreira Cavalcante, Waneska de Souza Barboza, Sidney Michael dos Santos Costa, Marina Sena da Silva Carneiro, Karine Dantas Moura, Carlos Henrique Lordelo dos Reis, Cliomar Alves dos Santos
Highlights This emerging case of feline-transmitted sporotrichosis in a non-endemic area underscores the global rise and geographical expansion of the disease, necessitating vigilant epidemiological surveillance in Brazil.
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Dengue severity in travellers: challenges and insights. J. Travel Med. (IF 25.7) Pub Date : 2023-11-22 Sarah L McGuinness,Karin Leder
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Temporal trends and spatial distribution of Brazilian spotted fever in Brazil. J. Travel Med. (IF 25.7) Pub Date : 2023-11-18 Victor S Santos,Thayane S Siqueira,José R S Silva
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Characteristics of possible mpox reinfection cases: literature review. J. Travel Med. (IF 25.7) Pub Date : 2023-11-18 Stefano Musumeci,Jérôme Laflamme,Laurent Kaiser,Olivier Segeral,Alexandra Calmy
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Comparison of clinical and laboratory parameters of primary vs secondary dengue fever in travellers. J. Travel Med. (IF 25.7) Pub Date : 2023-11-18 Sharon Avrami,Tomer Hoffman,Eyal Meltzer,Yaniv Lustig,Eli Schwartz
BACKGROUND Dengue fever (DF), caused by the dengue virus (DENV), is the most common arboviral disease in travellers worldwide. It is hypothesized that compared with primary DF, secondary DF may result in antibody-dependent enhancement of the immune response, resulting in more severe disease. We aimed to compare clinical and laboratory parameters in travellers with primary and secondary DF to determine
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Evolutionary history of human infections with highly pathogenic H5 avian influenza A virus: a new front-line global health threat established in South America. J. Travel Med. (IF 25.7) Pub Date : 2023-11-18 Alfredo Bruno,Doménica de Mora,Maritza Olmedo,Jimmy Garcés,Alonzo Alfaro-Núñez,Miguel A Garcia-Bereguiain
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Epidemiology and burden of dengue fever in the United States: a systematic review. J. Travel Med. (IF 25.7) Pub Date : 2023-11-18 Lin H Chen,Carlos Marti,Clemente Diaz Perez,Bianca M Jackson,Alyssa M Simon,Mei Lu
BACKGROUND Dengue is currently a global concern. The range of dengue vectors is expanding with climate change, yet United States of America (USA) studies on dengue epidemiology and burden are limited. This systematic review sought to characterize the epidemiology and disease burden of dengue within the USA. METHODS Studies evaluating travel-related and endemic dengue in US states and territories were
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Travel and tourism to the Kingdom of Saudi Arabia: what are the health risks? J. Travel Med. (IF 25.7) Pub Date : 2023-11-17 Ziad A Memish, Tariq Memish, Rana F Kattan
Highlight Tourism in Saudi Arabia has been rapidly growing and evolving in recent years as part of the Saudi government’s efforts to diversify its economy away from oil dependence and promote the country as a tourist destination. The country aims to invest $800 billion in the next decade, particularly targeting international travellers.
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Reduced splenic function can mimic artemisinin resistance in severe malaria J. Travel Med. (IF 25.7) Pub Date : 2023-11-13 Camille Roussel, Alexandra Serris, Benoît Henry, Barthelemy Lafon Desmurs, Emilie Sitterlé, Marie Elisabeth Bougnoux, Nicolas Argy, Sébastien Larréché, Mariane De Montalembert, Vincent Ioos, Ilhame Tantaoui, Charlotte Chambrion, Aurélie Fricot, Claire Rouzaud, Fanny Lanternier, Olivier Lortholary, Sandrine Houzé, Stéphane Jauréguiberry, Marc Thellier, Papa Alioune Ndour, Pierre Buffet
HIGHLIGHT We describe severe post-treatment episodes that complicate Plasmodium falciparum malaria in patients with hyposplenism, characterized by prolonged circulation of red cells containing dead parasites (hearse red cells), persistent or recurrent fever, profound anaemia, and inflammation. Asplenia-related Post-antimalarial Inflammation & Hemolysis (APIH) mimics concomitant infection and parasite
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R21/Matrix-M™ malaria vaccine: a new tool to achieve WHO`s goal to eliminate malaria in 30 countries by 2030 ? J. Travel Med. (IF 25.7) Pub Date : 2023-11-12 Blaise Genton
Highlight A potential breakthrough in the fight against malaria is the availability of a new promising tool, the R21/Matrix-M™ malaria vaccine that has shown an efficacy of 75% to protect young children against clinical malaria in different epidemiological settings. WHO recommends its deployment in addition to RTS,S/ASO1 and other effective interventions.
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Diagnostic challenges and antibody kinetics in a pediatric traveler with scrub typhus J. Travel Med. (IF 25.7) Pub Date : 2023-11-12 Panita Looareesuwan, Kristen Aiemjoy, Sakarn Charoensakulchai, Janjira Thaipadungpanit, Jantana Wongsantichon, Ampai Tanganuchitcharnchai, Artharee Rungrojn, Stuart D Blacksell, Wasin Matsee
Highlight Diagnosing scrub typhus in travellers is challenging due to symptom similarities with other travel-related illnesses and limited early diagnostic tools. We present a distinctive case of scrub typhus in a child traveller, providing a comprehensive account of the case, the diagnostic challenges encountered, laboratory findings, and the dynamics of antibodies.