-
Climate change and the spread of Aedes mosquito-borne viruses in Europe Pathog. Glob. Health (IF 3.4) Pub Date : 2024-02-29 Giovanni Rezza
Several outbreaks of chikungunya and dengue occurred on Mediterranean coasts during the hot season in the last two decades. Aedes albopictus was the vector involved in all the events. As a conseque...
-
Urinary schistosomiasis and anemia among school-aged children from southwestern Nigeria Pathog. Glob. Health (IF 3.4) Pub Date : 2024-02-28 Babatunde Adewale, Margaret A. Mafe, Hammed O. Mogaji, Joshua B. Balogun, Medinat A. Sulyman, Morakinyo B. Ajayi, David O. Akande, Emmanuel O. Balogun
Schistosomiasis and anemia, are one of the leading global public health problem among children between age 5 and 14 years in marginalized settings. In this study, we provide prevalence and intensit...
-
Monitoring avian influenza in mammals with real-time data Pathog. Glob. Health (IF 3.4) Pub Date : 2024-02-27 Francesco Branda, Marta Giovanetti, Fabio Scarpa, Massimo Ciccozzi
Published in Pathogens and Global Health (Ahead of Print, 2024)
-
Infodemiology and infoveillance: framework for contagious exanthematous diseases, of childhood in Italy Pathog. Glob. Health (IF 3.4) Pub Date : 2024-02-27 Sandro Provenzano, Omar Enzo Santangelo, Vincenza Gianfredi
Contagious exanthematous diseases are becoming a major public health problem. The purpose of this study was to evaluate the potential epidemiological trend of four infectious exanthematous diseases...
-
Modeling the health impact of increasing vaccine coverage and nonpharmaceutical interventions against coronavirus disease 2019 in Ghana Pathog. Glob. Health (IF 3.4) Pub Date : 2024-02-06 Sylvia K. Ofori, Jessica S. Schwind, Kelly L. Sullivan, Gerardo Chowell, Benjamin J. Cowling, Isaac Chun-Hai Fung
Seroprevalence studies assessing community exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Ghana concluded that population-level immunity remained low as of February 202...
-
Efficacy of artemether against toxocariasis in mice: parasitological and immunopathological changes in brain, liver, and lung Pathog. Glob. Health (IF 3.4) Pub Date : 2024-01-02 Dina I. Elgendy, Rasha A. Elmahy, Alaa Ibrahim Mohamed Amer, Hoda A. Ibrahim, Asmaa Fawzy Eltantawy, Fotouh Rashed Mansour, Amina M. Salama
Toxocariasis is a zoonosis that represents a serious threat to public health particularly in tropical and subtropical areas. Currently, albendazole, the most effective drug for treating visceral to...
-
Neglected tropical disease (NTD) diagnostics: current development and operations to advance control Pathog. Glob. Health (IF 3.4) Pub Date : 2024-01-02 Oyetunde T. Oyeyemi, Olumide Ogundahunsi, Mirjam Schunk, Ramzy G. Fatem, Lisa M. Shollenberger
Neglected tropical diseases (NTDs) have become important public health threats that require multi-faceted control interventions. As late treatment and management of NTDs contribute significantly to...
-
A historical perspective on arboviruses of public health interest in Southern Africa Pathog. Glob. Health (IF 3.4) Pub Date : 2023-12-11 Faith T. T. Hungwe, Katherine M. Laycock, Tlhalefo D. Ntereke, Rorisang Mabaka, Giacomo M. Paganotti
Arboviruses are an existing and expanding threat globally, with the potential for causing devastating health and socioeconomic impacts. Mitigating this threat necessitates a One Health approach tha...
-
Cryptosporidium sp. infection in solid organ transplant recipients: A systematic review and meta-analysis Pathog. Glob. Health (IF 3.4) Pub Date : 2023-12-06 Shahira Abdelaziz Ali Ahmed, Annalisa Quattrocchi, Panagiotis Karanis
(1) Background: Organ transplant recipients (OTRs) are vulnerable groups at risk of parasitic infections. This systematic review and meta-analysis aimed to evaluate the overall prevalence of Crypto...
-
Staphylococcus aureus epidemiology, pathophysiology, clinical manifestations and application of nano-therapeutics as a promising approach to combat methicillin resistant Staphylococcus aureus Pathog. Glob. Health (IF 3.4) Pub Date : 2023-11-25 Raghad H.F. Bashabsheh, O’la AL-Fawares, Iyad Natsheh, Roba Bdeir, Rozan O. Al-Khreshieh, Hasan H.F. Bashabsheh
Staphylococcus aureus is a Gram-positive bacterium and one of the most prevalent infectious disease-related causes of morbidity and mortality in adults. This pathogen can trigger a broad spectrum o...
-
A systematic review of CQ-resistant Plasmodium vivax malaria infections in India Pathog. Glob. Health (IF 3.4) Pub Date : 2023-11-23 Vishnu Teja Nallapati, Nitin Gupta, Manjunath H Hande, Kavitha Saravu
Chloroquine (CQ) is the drug of choice for treating uncomplicated Plasmodium vivax (P. vivax) malaria in India. The knowledge about the exact burden of CQ resistance in P. vivax in India is scarce....
-
COVID-19 vaccine acceptance and hesitancy in Indian context: a systematic review and meta-analysis Pathog. Glob. Health (IF 3.4) Pub Date : 2023-11-20 Sangeeta Dey, Yadlapalli S. Kusuma, Shashi Kant, Dewesh Kumar, Retheesh Babu Gopalan, Parikipandla Sridevi, Sumit Agarwal
Vaccination against COVID-19 is vital for achieving herd immunity, and the Government of India has adopted several strategies to achieve coverage. Vaccine hesitancy was identified as a potential ob...
-
How climate change influences pathogen transmission Pathog. Glob. Health (IF 3.4) Pub Date : 2023-11-18 Ahmad Z. Al Meslamani
Published in Pathogens and Global Health (Ahead of Print, 2023)
-
Land-cover, land-use and human hantavirus infection risk: a systematic review Pathog. Glob. Health (IF 3.4) Pub Date : 2023-10-24 Giovenale Moirano, Annarita Botta, Mingyou Yang, Martina Mangeruga, Kris Murray, Paolo Vineis
Previous studies suggest that the risk of human infection by hantavirus, a family of rodent-borne viruses, might be affected by different environmental determinants such as land cover, land use and...
-
Impact of the COVID-19 pandemic on malaria in pregnancy indicators in Northern Uganda: a joinpoint regression analysis Pathog. Glob. Health (IF 3.4) Pub Date : 2023-10-23 Francesco Vladimiro Segala, Jerry Ictho, Mariangela L’Episcopia, Emmanuel Onapa, Elda De Vita, Roberta Novara, Nelson Olung, Valentina Totaro, Lameck Olal, Giulia Patti, Christopher Bingom, Umberto Farina, Roberta Papagni, Caroline Agaro, Davide Fiore Bavaro, James Amone, Giovanni Dall’Oglio, Benedict Ngole, Claudia Marotta, Samuel Okori, Maurizio Zarcone, Joseph Ogwang, Carlo Severini, Peter Lochoro
Pregnancy is both a risk factor for P. falciparum infection and development of severe malaria. In low- and middle-income countries, the COVID-19 pandemic severely impacted health systems, including...
-
Capacity building for infectious disease control in Sub-Saharan Africa Pathog. Glob. Health (IF 3.4) Pub Date : 2023-10-18 William C. Lieber, Faraan O. Rahim, Henry S.Q. Lartey, Devesh Shah, Blandina T. Mmbaga, Nathan M. Thielman, Julian T. Hertz
Published in Pathogens and Global Health (Ahead of Print, 2023)
-
Web-based intervention for improving influenza vaccination in pregnant women: a cost-effectiveness analysis Pathog. Glob. Health (IF 3.4) Pub Date : 2023-10-16 Yingcheng Wang, Ginenus Fekadu, Joyce H.S. You
A website with vaccine information and interactive social media was reported to improve maternal influenza vaccine uptake. This study aimed to evaluate cost-effectiveness of a web-based interventio...
-
Beyond gain of function: strengthening oversight of research with potential pandemic pathogens Pathog. Glob. Health (IF 3.4) Pub Date : 2023-10-04 Gregory D. Koblentz, Rocco Casagrande
In 2017, the Department of Health and Human Services adopted a policy, known as the P3CO Framework, to govern proposed research that could enhance the lethality or transmissibility of a potential p...
-
Limiting open science? Three approaches to bottom-up governance of dual-use research of concern Pathog. Glob. Health (IF 3.4) Pub Date : 2023-10-04 Go Yoshizawa, Nariyoshi Shinomiya, Shishin Kawamoto, Naoto Kawahara, Daisuke Kiga, Ken-Ichi Hanaki, Jusaku Minari
Governing dual-use research of concern (DURC) in the life sciences has become difficult owing to the diversification of scientific domains, digitalization of potential threats, and the proliferatio...
-
Human mpox: global trends, molecular epidemiology and options for vaccination Pathog. Glob. Health (IF 3.4) Pub Date : 2023-09-16 Lorenzo Subissi, Paola Stefanelli, Giovanni Rezza
The eradication of smallpox and the cessation of vaccination have led to the growth of the susceptible human population to poxviruses. This has led to the increasing detection of zoonotic orthopoxv...
-
Genetic diversity and evolutionary dynamics of the Omicron variant of SARS-CoV-2 in Morocco Pathog. Glob. Health (IF 3.4) Pub Date : 2023-08-27 Safae El Mazouri, Abdelmounim Essabbar, Tarik Aanniz, Rachid Eljaoudi, Lahcen Belyamani, Azeddine Ibrahimi, Mouna Ouadghiri
ABSTRACT Among the numerous variants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) that have been reported worldwide, the emergence of the Omicron variant has drastically changed the landscape of the coronavirus disease (COVID-19) pandemic. Here, we analyzed the genetic diversity of Moroccan SARS-CoV-2 genomes with a focus on Omicron variant after one year of its detection in Morocco
-
Scientific literature on neglected tropical diseases: a bibliometric analysis Pathog. Glob. Health (IF 3.4) Pub Date : 2023-08-22 Gianpiero Tebano, Elisa Vanino, Paolo Muratori, Francesco Cristini
ABSTRACT Neglected tropical diseases (NTDs) are a group of diseases mainly affecting people in low- and middle-income Countries. The aim of this study was to perform a bibliometric analysis of the scientific literature on NTDs. Using the MeSH database, we quantified the number of publications on MEDLINE targeting each NTD, which were published from 1 January 1999 to 31 January 2019. In order to weight
-
Determining the relationship between dengue and vulnerability in a Brazilian city: a spatial modeling analysis Pathog. Glob. Health (IF 3.4) Pub Date : 2023-08-21 Bianca Conrad Bohm, Maria Helena Franco Morais, Maria da Consolação Magalhães Cunha, Nádia Campos Pereira Bruhn, Waleska Teixeira Caiaffa, Fábio Raphael Pascoti Bruhn
ABSTRACT Dengue is a viral infection transmitted by the Aedes aegypti mosquito. This study aimed to assess the distribution of cases and deaths from dengue and severe dengue, and its relationship with social vulnerability in Belo Horizonte, State of Minas Gerais, Brazil, from 2010 to 2018. The incidence and lethality rates of dengue and their relationship with sex, age, education, skin color, and social
-
Continued dominance of dengue virus serotype 2 during the recent Central India outbreaks (2019-2021) with evidence of genetic divergence Pathog. Glob. Health (IF 3.4) Pub Date : 2023-08-13 Ankita Agarwal, Ruchi Ganvir, Dipesh Kale, Deepti Chaurasia, Garima Kapoor
ABSTRACT Central India faced major dengue outbreaks in 2019 and 2021. In the present study, we aimed to identify the dengue virus serotypes and genotypes circulating in Central India during the COVID pre-pandemic year (2019) and ongoing-pandemic year (2021). For this purpose, the suspected cases were first tested by serological assays. Sero-positive samples were then subjected to molecular diagnosis
-
HPV and Covid-19 Era: effects of nonpharmaceutical interventions on HPV transmission Pathog. Glob. Health (IF 3.4) Pub Date : 2023-08-02 Ronga Luigi, Stolfa Stefania, Indraccolo Francesca, Romanelli Federica, Bavaro Davide Fiore, Saracino Annalisa, Di Gennaro Francesco, Milano Eugenio, Manuela Mandorino, Mosca Adriana, Sparapano Eleonora, De Carlo Carmela, Nisi Lucia, Ranieri Enrica, Mastria Michele, Montagna Maria Teresa, Del Prete Raffaele
Human papillomavirus (HPV) is considered the commonest viral cause of sexually transmitted infections. The impact of social distance measures due to Covid-19 pandemic on HPV spread is unknown. Ther...
-
Enhancing screening adherence for strongyloides infection in latinx inpatients with COVID-19: a local protocol implementation study Pathog. Glob. Health (IF 3.4) Pub Date : 2023-07-31 María Asunción Pérez-Jacoiste Asín, Marta De Castro, Begoña De Dios, Ana Pérez-Ayala, Antonio Lalueza, Ana García-Reyne, Irene Losada, Juan María Herrero-Martínez, Pilar Hernández Jiménez, Carlos Lumbreras, Manuel Lizasoain, Francisco López Medrano
ABSTRACT Strongyloides stercoralis hyperinfection syndrome has been observed in immunosuppressed coronavirus disease 2019 (COVID-19) patients. Detecting and treating asymptomatic Strongyloides infection in individuals from endemic areas can effectively prevent hyperinfection. Unfortunately, many clinicians are unaware of this neglected infection. Therefore, we aimed to evaluate whether including Strongyloides
-
Stem cell-derived exosomes as a potential therapy for schistosomal hepatic fibrosis in experimental animals Pathog. Glob. Health (IF 3.4) Pub Date : 2023-07-30 Asmaa R. Ellakany, Hanan El Baz, Zeinab S. Shoheib, Mohamed Elzallat, Dalia S. Ashour, Nabila A. Yassen
ABSTRACT Schistosomiasis is a neglected tropical disease. Egg-induced granuloma formation and tissue fibrosis are the main causes of the high morbidity and mortality of schistosomiasis. Mesenchymal stem cells (MSCs)-derived exosomes play an important role with a superior safety profile than MSCs in the treatment of liver fibrosis. Therefore, the aim of this study was to investigate the potential therapeutic
-
Evolution of COVID-19 infection characteristics in a Lebanese cohort of inpatients during different pandemic periods Pathog. Glob. Health (IF 3.4) Pub Date : 2023-07-23 Tony Haykal, Jonathan Mina, Mohamad Fleifel, Hani Dimassi, Janane Nasr, Ahmad Mahdi, Ranime Harb, Ghida El Hout, Elissar Franjieh, Jacques Mokhbat, Anna Farra, Mariana Helou, Rola Husni
ABSTRACT This study aims to describe COVID-19 patients characteristics, laboratory and imaging results, and the different outcomes of patients admitted to the Lebanese American University Medical Center-Rizk Hospital over a period of 9 months. In this observational retrospective study, data were obtained from electronic medical records of 491 male and female patients from the ages of 17 to 97. Analysis
-
Evolutionary trajectories of beta-lactamase NDM and DLST cluster in Pseudomonas aeruginosa: finding the putative ancestor Pathog. Glob. Health (IF 3.4) Pub Date : 2023-07-18 Parisa Sadeghi, Karim Mahnam, Azhar Salari-Jazi, Ashok Aspatwar, Jamshid Faghri
ABSTRACT Pseudomonas aeruginosa has different antibiotic resistance pathways, such as broad-spectrum lactamases and metallo-β-lactamases (MBL), penicillin-binding protein (PBP) alteration, and active efflux pumps. Polymerase chain reaction (PCR) and sequencing methods were applied for double-locus sequence typing (DLST) and New Delhi metallo-β-lactamase (NDM) typing. We deduced the evolutionary pathways
-
Malaria diagnosis using a combined system of a simple and fast extraction method with a lyophilised Dual-LAMP assay in a non-endemic setting Pathog. Glob. Health (IF 3.4) Pub Date : 2023-07-06 Alexandra Martín Ramírez, Lourdes Barón Argos, Marta Lanza Suárez, Claudia Carmona Rubio, Ana Pérez-Ayala, Shamilah R. Hisam, José M. Rubio
Malaria is a parasitic disease distributed in tropical areas but with a high number of imported cases in non-endemic countries. The most specific and sensitive malaria diagnostic methods are PCR an...
-
Molnupiravir as the COVID-19 panacea: false beliefs in low- and middle-income countries Pathog. Glob. Health (IF 3.4) Pub Date : 2023-07-03 Ngoc-Ha Tran, Nguyen Khoi Quan, Van Phu Tran, Dang Nguyen, Ngoc Phuong Hong Tao, Nguyen Ngoc Hoang Linh, Nguyen Tien Huy
Published in Pathogens and Global Health (Vol. 117, No. 6, 2023)
-
A narrative review of alternative transmission routes of COVID 19: what we know so far Pathog. Glob. Health (IF 3.4) Pub Date : 2023-06-23 Alyexandra Arienzo, Valentina Gallo, Federica Tomassetti, Nicoletta Pitaro, Michele Pitaro, Giovanni Antonini
The Coronavirus disease 19 (COVID-19) pandemics, caused by severe acute respiratory syndrome coronaviruses, SARS-CoV-2, represent an unprecedented public health challenge. Beside person-to-person c...
-
The importance of rapid and robust availability of epidemiological data for real-time mapping of the risk of avian influenza A (H5N1) spread Pathog. Glob. Health (IF 3.4) Pub Date : 2023-06-20 Francesco Branda, Sandra Mazzoli
Published in Pathogens and Global Health (Vol. 117, No. 6, 2023)
-
Knowledge of the Mpox virus and conspiracy beliefs and their association with self-confidence in managing the virus among Israeli orthopedic surgeons Pathog. Glob. Health (IF 3.4) Pub Date : 2023-06-20 Rawan Masarwa, Yaniv Yonai, Merav Ben-Natan, Yaron Berkovich
In 2022, the Mpox viral outbreak signaled a global public health emergency. Infectious disease management and prevention are crucial tasks for healthcare workers. In their line of work, orthopedic ...
-
High seropositivity against NDO-LID in a group of household contacts of leprosy patients. Are we close to leprosy elimination in Colombia? Pathog. Glob. Health (IF 3.4) Pub Date : 2023-05-25 Héctor Serrano-Coll, Mónica Muñoz, Juan Camilo Beltrán, Nora Cardona-Castro
Introduction. Leprosy is a chronic infectious disease caused by two mycobacteria (Mycobacterium leprae and Mycobacterium lepromatosis). The household contacts (HHC) of leprosy index cases are at hi...
-
Infectious disease burden among forcibly displaced populations: considerations for effective research Pathog. Glob. Health (IF 3.4) Pub Date : 2023-05-23 Carly Ching, Muhammad H Zaman
Published in Pathogens and Global Health (Vol. 117, No. 5, 2023)
-
A novel outlook in the delivery of artemisinin: production and efficacy in experimental visceral leishmaniasis Pathog. Glob. Health (IF 3.4) Pub Date : 2023-05-15 Maryam Akbari, Hossein Heli, Ahmad Oryan, Gholamreza Hatam
The visceral form of leishmaniasis (VL), due to infection by Leishmania infantum, is a neglected tropical disease. The accessible therapeutic options are limited. Artemisinin is an efficient antile...
-
Impact of public health policy and mobility change on transmission potential of severe acute respiratory syndrome coronavirus 2 in Rhode Island, March 2020 – November 2021 Pathog. Glob. Health (IF 3.4) Pub Date : 2023-04-19 Chigozie A. Ogwara, Jennifer W. Ronberg, Sierra M. Cox, Briana M. Wagner, Jacqueline W. Stotts, Gerardo Chowell, Anne C. Spaulding, Isaac Chun-Hai Fung
To study the SARS-CoV-2 transmission potential in Rhode Island (RI) and its association with policy changes and mobility changes, the time-varying reproduction number, Rt, was estimated. The daily ...
-
Customized molecular diagnostics of bacterial bloodstream infections for carbapenem resistance: A convenient and affordable approach Pathog. Glob. Health (IF 3.4) Pub Date : 2023-04-17 Abhi Mallick, Abhiparna Roy, Soma Sarkar, Keshab Ch. Mondal, Surojit Das
ABSTRACT The acute crisis of carbapenem resistance impedes the empirical use of carbapenems in medical emergencies, especially, bloodstream infections. Carbapenemase-producing carbapenem-resistant organisms (CP-CROs) attribute high case-fatality, necessitating rapid diagnostics to initiate early targeted antibiotics. Expensive diagnostics are the major driver of antibiotic misuse, neglecting evidence-based
-
Monkeypox in Latin America and the Caribbean: assessment of the first 100 days of the 2022 outbreak Pathog. Glob. Health (IF 3.4) Pub Date : 2023-04-14 Antonio M. Quispe, Jesús M Castagnetto
During the 2022 monkeypox (mpox) epidemic’s first 100 days, 99 non-endemic countries, including 25 Latin American and Caribbean (LAC) countries, reported >64,000 cases. We aim to assess the cases’ ...
-
Avian influenza A H5N1: are we really sure it is a spillover? Pathog. Glob. Health (IF 3.4) Pub Date : 2023-04-12 Fabio Scarpa, Daria Sanna, Marta Giovanetti, Stefano Pascarella, Marco Casu, Massimo Ciccozzi
Published in Pathogens and Global Health (Vol. 117, No. 4, 2023)
-
Evaluation of mono and combined nitrofurantoin therapy for toxoplasmosis in vivo using murine model Pathog. Glob. Health (IF 3.4) Pub Date : 2023-04-09 Asmaa Elkholy, Rita Wassef, Omnia Alsaid, Mona Elawady, Ashraf Barakat, Ashraf Soror, Shereen Kishik
ABSTRACT Toxoplasmosis is a frequent disease with an estimated prevalence of more than one billion human cases worldwide and over one million new infections each year. It is classified as a neglected tropical disease by the CDC since 2019. The disease may pass unnoticed in healthy individuals but could be fatal in the immunocompromised. Moreover, no effective treatment is available against the chronic
-
Animal and environmental risk factors for sporadic Shiga toxin-producing Escherichia coli (STEC) infection in England: a case control study for O157, O26 and other STEC serotypes Pathog. Glob. Health (IF 3.4) Pub Date : 2023-04-04 Erica Kintz, Julii Brainard, Mike Vanderes, Roberto Vivancos, Lisa Byrne, Saira Butt, Claire Jenkins, Richard Elson, Iain Lake, Paul Hunter
ABSTRACT Most Shiga toxin-producing E. coli (STEC) infections are sporadic. Routine enhanced surveillance questionnaires of confirmed STEC cases in England contained promising data to conduct a case-control study to identify non-food exposures linked to the risk of becoming infected with different STEC serotypes, including O157, O26 and all others; this study pulled eligible cases from the recorded
-
Recrudescence of measles in India: an emerging threat Pathog. Glob. Health (IF 3.4) Pub Date : 2023-03-30 Akshay Raut, Nguyen Tien Huy
Published in Pathogens and Global Health (Vol. 117, No. 4, 2023)
-
Determinants of SARS-CoV-2 nasopharyngeal testing in a rural community sample susceptible of first infection: the CHRIS COVID-19 study Pathog. Glob. Health (IF 3.4) Pub Date : 2023-03-29 Daniele Giardiello, Roberto Melotti, Giulia Barbieri, Martin Gögele, Christian X. Weichenberger, Luisa Foco, Daniele Bottigliengo, Laura Barin, Rebecca Lundin, Peter P. Pramstaller, Cristian Pattaro
To characterize COVID-19 epidemiology, numerous population-based studies have been undertaken to model the risk of SARS-CoV-2 infection. Less is known about what may drive the probability to underg...
-
Impact assessment of Intensified Malaria Control Project in transitioning a high malaria-endemic district to a low-endemic district: an epidemiological aspect Pathog. Glob. Health (IF 3.4) Pub Date : 2023-03-24 Rahim Ali Ahmed, Avdhesh Kumar, Ananta Swargiary, Harpal Singh Suri, Hari Shankar, Syed Shah Areeb Hussain, Gaurav Kumar, Kuldeep Singh, Dipika Kalita, Afluza begum
ABSTRACT Intensified Malaria Control Project (IMCP) was implemented in 2005 to control malaria in all North-Eastern and Odisha states of India. The present study aimed to investigate the impact of IMCP in reducing the malaria burden in Udalguri district, Assam state of North-East India. Malaria epidemiological data were obtained for IMCP intervention (Udalguri) and nonintervention district (West Singhbhumi
-
Risk factors of HIV and variation in access to clean needles among people who inject drugs in Pakistan Pathog. Glob. Health (IF 3.4) Pub Date : 2023-03-22 Fernando Capelastegui, Adam Trickey, Laura H. Thompson, Tahira Reza, Faran Emmanuel, Francois Cholette, James F. Blanchard, Chris Archibald, Peter Vickerman, Aaron G. Lim
We identified key risk factors for HIV among people who inject drugs (PWID) in Pakistan and explored access to free clean needles. Multivariable logistic regression was used to investigate associat...
-
Immunomodulatory effects of chronic trichinellosis on Toxoplasma gondii RH virulent strain in experimental rats Pathog. Glob. Health (IF 3.4) Pub Date : 2023-03-15 Abeer E. Saad, Dalia S. Ashour, Eman Rashad
ABSTRACT Mixed parasitic infections could affect the host immunological responses and re-design the pathogenesis of each other. The impact of Toxoplasma gondii (T. gondii) and Trichinella spiralis (T. spiralis) co-infection on the immune response remains unclear. The objective of the present study was to investigate the possible effect of chronic trichinellosis on the immune response of rats infected
-
Use of Sotrovimab in a cohort of pregnant women with a high risk of COVID 19 progression: a single-center experience Pathog. Glob. Health (IF 3.4) Pub Date : 2023-03-10 Luisa Frallonardo, Antonella Vimercati, Roberta Novara, Cherola Lepera, Ilaria Ferrante, Giulia Chiarello, Rossana Cicinelli, Michele Mongelli, Gaetano Brindicci, Francesco Vladimiro Segala, Carmen Rita Santoro, Davide Fiore Bavaro, Nicola Laforgia, Ettore Cicinelli, Annalisa Saracino, Francesco Di Gennaro
ABSTRACT Neutralizing monoclonal antibodies (mAbs) have been shown to reduce disease progression in patients with underlying predisposing conditions. Unfortunately, there is no evidence on the use of Sotrovimab in pregnant women. Herein we present a case series of pregnant women who received mAbs with Sotrovimab following the Italian Drug Agency (AIFA) indications. Since February 1, 2022 all pregnant
-
Biogenic selenium nanoparticles: trace element with promising anti-toxoplasma effect Pathog. Glob. Health (IF 3.4) Pub Date : 2023-03-05 Fadwa M. Arafa, Nermine M. F. H. Mogahed, Marwa M. Eltarahony, Radwa G. Diab
ABSTRACT Toxoplasmosis is an opportunistic infection caused by the coccidian Toxoplasma gondii which represents a food and water contaminant. The available chemotherapeutic agents for toxoplasmosis are limited and the choice is difficult when considering the side effects. Selenium is an essential trace element. It is naturally found in dietary sources, especially seafood, and cereals. Selenium and
-
Medicinal plants as a source of antiparasitics: an overview of experimental studies Pathog. Glob. Health (IF 3.4) Pub Date : 2023-02-20 Sandamalie Ranasinghe, Anthony Armson, Alan J. Lymbery, Alireza Zahedi, Amanda Ash
ABSTRACT Despite advances in modern human and veterinary medicine, gastrointestinal (GI) parasitic infections remain a significant health issue worldwide, mainly in developing countries. Increasing evidence of the multi-drug resistance of these parasites and the side effects of currently available synthetic drugs have led to increased research on alternative medicines to treat parasitic infections
-
The increasing antimicrobial resistance of Shigella species among Iranian pediatrics: a systematic review and meta-analysis Pathog. Glob. Health (IF 3.4) Pub Date : 2023-02-16 Amirhossein Baharvand, Leila Molaeipour, Sogol Alesaeidi, Reyhane Shaddel, Noushin Mashatan, Taghi Amiriani, Melika Kiaei Sudkolaei, Sara Abbasian, Bashar Zuhair Talib Al-Naqeeb, Ebrahim Kouhsari
ABSTRACT Background Shigellosis remains one of the global causes of morbidity and mortality. However, the global emergence of antibiotic resistance has become the leading cause of treatment failure in shigellosis. This review aimed to provide an updated picture of the antimicrobial resistance rates in Shigella species in Iranian pediatrics. Methods A comprehensive systematic search was performed on
-
A comprehensive approach to the COVID-19 pandemic in Japan: telemanagement Pathog. Glob. Health (IF 3.4) Pub Date : 2023-02-15 Venkata Vasavi Vadduri, Ayako Toyokawa, Nguyen Ngoc Hoang Linh, Dang Nguyen, Jeza M Abdul Aziz, Norio Ohmagari, Nguyen Tien Huy
Published in Pathogens and Global Health (Vol. 117, No. 2, 2023)
-
Disparities between Latinx migrants and Spanish natives in COVID-19 outcome in Madrid Pathog. Glob. Health (IF 3.4) Pub Date : 2023-02-12 Begoña de Dios, Asunción Pérez-Jacoiste, Antonio Lalueza, Guillermo Maestro, Ana García-Reyne, Manuel Lizasoain, Carlos Lumbreras
ABSTRACT Previous studies have suggested an increased susceptibility of COVID-19 among certain populations. We analyzed whether COVID-19 presentation and mortality differ between Latinx migrants and Spanish natives. Methods and Materials. COVID-19 patients between 35–64 years old admitted between January 26th-May-5th 2020 were reviewed. Demographics, major comorbidities, symptoms, signs and analytical
-
Nasopharyngeal epithelial cells from patients with coronavirus disease 2019 express abnormal levels of Toll-like receptors Pathog. Glob. Health (IF 3.4) Pub Date : 2023-01-18 Zahra Bagheri-Hosseinabadi, Fahimeh Mohammadizadeh Ranjbar, Mohammad Nassiri, Ali Amiri, Mitra Abbasifard
ABSTRACT Aberrant activation of the immune system has been attributed with etiology and pathogenesis of coronavirus disease 2019 (COVID-19). Here, the transcript levels of toll-like receptors (TLRs) were measured in the nasopharyngeal epithelial cells obtained from COVID-19 patients to assess the involvement of these molecules in the clinical outcome of COVID-19 patients. Nasopharyngeal swab samples
-
Routine blood parameters of dengue infected children and adults. A meta-analysis Pathog. Glob. Health (IF 3.4) Pub Date : 2023-01-02 Gary KK Low, Sam Froze Jiee, Retneswari Masilamani, Selvanaayagam Shanmuganathan, Pramila Rai, Mitali Manda, Osamudiamen Favour Omosumwen, Jackob Kagize, Alex I. Gavino, Aizad Azahar, Mohammed Abdulrazzaq Jabbar
ABSTRACT The World Health Organization (WHO) has revised dengue case classification in 2009 to better reflect the severity of the disease. However, there was no comprehensive meta-analysis of pooled routine blood parameters according to the age or the categories of the 2009 WHO classification. This study aimed to meta-analyze the routine blood parameters of dengue infected children and adults. Electronic
-
Genes drive organisms and slippery slopes Pathog. Glob. Health (IF 3.4) Pub Date : 2022-12-22 David B. Resnik, Raul F. Medina, Fred Gould, George Church, Jennifer Kuzma
ABSTRACT The bioethical debate about using gene drives to alter or eradicate wild populations has focused mostly on issues concerning short-term risk assessment and management, governance and oversight, and public and community engagement, but has not examined big-picture— ‘where is this going?’—questions in great depth. In other areas of bioethical controversy, big-picture questions often enter the
-
Prevalence of antibiotics prescription amongst patients with and without COVID-19 in low- and middle-income countries: a systematic review and meta-analysis Pathog. Glob. Health (IF 3.4) Pub Date : 2022-12-22 Yohanes Aditya Adhi Satria, Monica Suci Utami, Alexander Prasudi
ABSTRACT Antimicrobial resistance (AMR) poses a substantial risk to public health. In low-income and middle-income (LMICs) nations, the impact of AMR is significantly more severe. The absence of data from low-income countries (LMICs) causes this topic to be frequently overlooked. Additionally, the COVID-19 pandemic could make the AMR issue even worse. Earlier guidelines recommended antibiotic use in
-
Epidemiology of free-living amoebae infections in Africa: a review Pathog. Glob. Health (IF 3.4) Pub Date : 2022-12-22 Giovanni D. Milanez, Karlo B. Carlos, Mary Erika Adao, Bernadette B Ayson, Ariela V. Dicon, Rhonette Anne M. Gahol, Sharmaine Kaye S. Lacre, Franchesca Pauline E. Marquez, April Jane M. Perez, Panagiotis Karanis
ABSTRACT FLA-related conditions are a rare medical occurrence. Despite their rarity, they are considered a public health concern for two reasons: the absence of a regular treatment regimen in the case of central nervous system infections and the fast progression of the symptoms leading to fatal outcomes. A total of 358 articles were retrieved from different databases (91 from PubMed, 26 from NCBI,
-
Circulating markers of neutrophil activation and lung injury in pediatric pneumonia in low-resource settings Pathog. Glob. Health (IF 3.4) Pub Date : 2022-12-22 Emily R. Konrad, Jeremy Soo, Andrea L. Conroy, Sophie Namasopo, Robert O. Opoka, Michael T. Hawkes
Diagnostic biomarkers for childhood pneumonia could guide management and improve antibiotic stewardship in low-resource settings where chest x-ray (CXR) is not always available. In this cross-secti...