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A molecular assessment of Ostertagia leptospicularis and Spiculopteragia asymmetrica among wild fallow deer in Northern Ireland and implications for false detection of livestock-associated species Parasites Vectors (IF 3.2) Pub Date : 2024-03-18 Maggie Lyons, Tony L. Brown, Angela Lahuerta-Marin, Eric. R. Morgan, Paul M. Airs
Wild deer populations utilizing livestock grazing areas risk cross-species transmission of gastrointestinal nematode parasites (GINs), including GINs with anthelmintic resistance (AR) traits. Wild deer have been shown to carry problematic GIN species such as Haemonchus contortus and Trichostrongylus species in the UK, but the presence of livestock GINs in Northern Ireland deer populations is unknown
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Accelerating targeted mosquito control efforts through mobile West Nile virus detection Parasites Vectors (IF 3.2) Pub Date : 2024-03-18 Zsaklin Varga, Rubén Bueno-Marí, José Risueño Iranzo, Kornélia Kurucz, Gábor Endre Tóth, Brigitta Zana, Safia Zeghbib, Tamás Görföl, Ferenc Jakab, Gábor Kemenesi
Different mosquito control strategies have been implemented to mitigate or prevent mosquito-related public health situations. Modern mosquito control largely relies on multiple approaches, including targeted, specific treatments. Given this, it is becoming increasingly important to supplement these activities with rapid and mobile diagnostic capacities for mosquito-borne diseases. We aimed to create
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New insights into the molecular phylogeny, biogeographical history, and diversification of Amblyomma ticks (Acari: Ixodidae) based on mitogenomes and nuclear sequences Parasites Vectors (IF 3.2) Pub Date : 2024-03-18 Juan E. Uribe, Samuel Kelava, Santiago Nava, Andrea P. Cotes-Perdomo, Lyda R. Castro, Fredy A. Rivera-Paéz, Silvia Perea, Ben J. Mans, Alexander Gofton, Ernest J. M. Teo, Rafael Zardoya, Stephen C. Barker
Amblyomma is the third most diversified genus of Ixodidae that is distributed across the Indomalayan, Afrotropical, Australasian (IAA), Nearctic and Neotropical biogeographic ecoregions, reaching in the Neotropic its highest diversity. There have been hints in previously published phylogenetic trees from mitochondrial genome, nuclear rRNA, from combinations of both and morphology that the Australasian
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Low diagnostic performance of thick blood smears of 50 µl in comparison with direct examination of 10 µl blood and the leukoconcentration technique of 5ml blood among loiasis-suspected patients with low microfilaremia in Gabon, Central Africa, using the STARD-BLCM guidelines Parasites Vectors (IF 3.2) Pub Date : 2024-03-15 Noé Patrick M’Bondoukwé, Matthieu Owono-Medang, Marie Noëlle Moussavou-Boussougou, Yvan Akoue, Valentin Migueba, Dmitry Bulaev, Anouk Neven, Luice Aurtin Joel James, Sylvie Alberte Ntsame Ella, Denise Patricia Mawili-Mboumba, Julienne Atsame, Michel Vaillant, Marielle Karine Bouyou Akotet
The aim of this study was to determine performance indicators of thick blood smears of 50 µl (TBS-50), following the Standards for the Reporting of Diagnostic Accuracy Studies–Bayesian Latent Class Model (STARD-BLCM) guidelines. TBS-50 was compared with two common parasitological techniques—direct examination of 10 µl blood and a leukoconcentration of 5 ml—for the diagnosis of microfilaremic loiasis
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Onchocerca volvulus microfilariae in the anterior chambers of the eye and ocular adverse events after a single dose of 8 mg moxidectin or 150 µg/kg ivermectin: results of a randomized double-blind Phase 3 trial in the Democratic Republic of the Congo, Ghana and Liberia Parasites Vectors (IF 3.2) Pub Date : 2024-03-15 Eric M. Kanza, Amos Nyathirombo, Jemmah P. Larbelee, Nicholas O. Opoku, Didier K. Bakajika, Hayford M. Howard, Germain L. Mambandu, Maurice M. Nigo, Deogratias Ucima Wonyarossi, Françoise Ngave, Kambale Kasonia Kennedy, Kambale Kataliko, Kpehe M. Bolay, Simon K. Attah, George Olipoh, Sampson Asare, Mupenzi Mumbere, Michel Vaillant, Christine M. Halleux, Annette C. Kuesel
After ivermectin became available, diethylcarbamazine (DEC) use was discontinued because of severe adverse reactions, including ocular reactions, in individuals with high Onchocerca volvulus microfilaridermia (microfilariae/mg skin, SmfD). Assuming long-term ivermectin use led to < 5 SmfD with little or no eye involvement, DEC + ivermectin + albendazole treatment a few months after ivermectin was proposed
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New artificial hematophagy system with attractive polymeric biofilm for maintenance of Culex quinquefasciatus (Diptera: Culicidae) in the laboratory Parasites Vectors (IF 3.2) Pub Date : 2024-03-15 Angelita Milech, Caroline Quintana Braga, Carolina dos Santos Bermann, Jaqueline Ferreira de Souza, André Ricardo Fajardo, Élvia Silveira Vianna, Camila Belmonte Oliveira
Maintaining mosquito colonies in the laboratory requires a blood supply so that females' oocytes can mature and oviposition can take place. In this study, a new artificial hematophagy system for colonization and maintenance of Culex quinquefasciatus in the laboratory was developed and tested. We developed an attractive polymeric biofilm including 25% l-lactic acid for use as a membrane in an artificial
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A cyst-forming coccidian with large geographical range infecting forest and commensal rodents: Sarcocystis muricoelognathis sp. nov. Parasites Vectors (IF 3.2) Pub Date : 2024-03-15 Tao Qin, Paula Ortega-Perez, Gudrun Wibbelt, Maklarin B. Lakim, Sulaiman Ginting, Yuvaluk Khoprasert, Konstans Wells, Junjie Hu, Thomas Jäkel
The geographic distribution and host-parasite interaction networks of Sarcocystis spp. in small mammals in eastern Asia remain incompletely known. Experimental infections, morphological and molecular characterizations were used for discrimination of a new Sarcocystis species isolated from colubrid snakes and small mammals collected in Thailand, Borneo and China. We identified a new species, Sarcocystis
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Impact of climate change on temperature variations and extrinsic incubation period of malaria parasites in Chennai, India: implications for its disease transmission potential Parasites Vectors (IF 3.2) Pub Date : 2024-03-15 P. K. Kripa, P. S. Thanzeen, Nagaraj Jaganathasamy, Sangamithra Ravishankaran, Anupkumar R. Anvikar, Alex Eapen
The global temperature has significantly risen in the past century. Studies have indicated that higher temperature intensifies malaria transmission in tropical and temperate countries. Temperature fluctuations will have a potential impact on parasite development in the vector Anopheles mosquito. Year-long microclimate temperatures were recorded from a malaria-endemic area, Chennai, India, from September
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Correction: Avian Plasmodium in invasive and native mosquitoes from southern Spain Parasites Vectors (IF 3.2) Pub Date : 2024-03-15 Marta Garrigós, Jesús Veiga, Mario Garrido, Clotilde Marín, Jesús Recuero, María José Rosales, Manuel Morales-Yuste, Josué Martínez-de la Puente
Correction: Parasites & Vectors (2024) 17:40 https://doi.org/10.1186/s13071-024-06133-8 Following publication of the original article [1], the authors flagged that they had erroneously omitted the following acknowledgement of Funding from the declaration of their article: Finally, this paper was financed by Programa QUALIFICA, Junta de Andalucía, Consejería de Universidad, Investigación e Innovación
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The spleen is the graveyard of CD4+ cells in patients with immunological failure of visceral leishmaniasis and AIDS Parasites Vectors (IF 3.2) Pub Date : 2024-03-15 Luis Gustavo Cavalcante Reinaldo, Raimundo José Cunha Araújo Júnior, Thiago Melo Diniz, Rafael de Deus Moura, Antônio José Meneses Filho, Caio Victor Verçosa de Macedo Furtado, Washington Luis Conrado dos Santos, Dorcas Lamounier Costa, Kelsen Dantas Eulálio, Gabriel R. Ferreira, Carlos Henrique Nery Costa
Visceral leishmaniasis (VL), or kala-azar, is a common comorbidity in patients with AIDS in endemic areas. Many patients continue to experiences relapses of VL despite virological control, but with immunological failure. These patients remain chronically symptomatic with hypersplenism, for example with anemia, leukopenia, and thrombocytopenia, and are at risk of severe co-infection due to low CD4+
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A phenotypic screen of the Global Health Priority Box identifies an insecticide with anthelmintic activity Parasites Vectors (IF 3.2) Pub Date : 2024-03-14 Harrison T. Shanley, Aya C. Taki, Joseph J. Byrne, Nghi Nguyen, Tim N. C. Wells, Abdul Jabbar, Brad E. Sleebs, Robin B. Gasser
Infection with parasitic nematodes (helminths), particularly those of the order Strongylida (such as Haemonchus contortus), can cause significant and burdensome diseases in humans and animals. Widespread drug (anthelmintic) resistance in livestock parasites, the absence of vaccines against most of these nematodes, and a lack of new and effective chemical entities on the commercial market demands the
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Investigating the effect of a school-based WASH intervention on soil-transmitted helminth and schistosome infections and nutritional status of school children in Ethiopia: a quasi-experimental study Parasites Vectors (IF 3.2) Pub Date : 2024-03-14 Gemechu Tadesse, Yonas Wuletaw, Kalkidan Mekete, Heven Sime, Elodie Yard, Laura Appleby, Jack Grimes, Nigussie Dejene, Iain Gardiner, Adama Kazienga, Souheila Abbeddou, Michael French, Bruno Levecke, Lesley Drake
The impact of access to improved water, sanitation and hygiene (WASH) and health education on large-scale deworming programs aimed at controlling soil-transmitted helminth (STH) and schistosome (SCH) infections has not been well studied. We assessed the additional impact of improved WASH infrastructure and health education at schools on STH and SCH infections in Ethiopia. The study used a quasi-experimental
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Biology of the non-parasitic phase of the cattle tick Rhipicephalus (Boophilus) microplus in an area of Amazon influence Parasites Vectors (IF 3.2) Pub Date : 2024-03-14 Daniela P. Sales, Marcelo H. S. Silva-Junior, Caio P. Tavares, Isabella C. Sousa, Dauana M. Sousa, Danilo R. B. Brito, André M. Camargo, Romário Cerqueira Leite, J. L. H. Faccini, Welber D. Z. Lopes, Marcelo B. Labruna, Hermes R. Luz, Livio M. Costa-Junior
Rhipicephalus (Boophilus) microplus is the most important tick species affecting cattle in the world. Under field conditions, the non-parasitic phase of R. (B.) microplus is unknown in the Amazon biome, including Brazil. The present study aimed to evaluate the non-parasitic phase of R. (B.) microplus in field (grass plots) and laboratory conditions. The study was conducted from September 2020 to April 2022
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Cystic echinococcosis in cattle and sheep caused by Echinococcus granulosus sensu stricto genotypes G1 and G3 in the USA Parasites Vectors (IF 3.2) Pub Date : 2024-03-14 Jeba R. J. Jesudoss Chelladurai, Theresa A. Quintana, William L. Johnson, Carrie Schmidt, Daniel Righter, Erin Howey
Endemic domestic dog-ruminant cycles and human cystic echinococcosis caused by Echinococcus granulosus have been sporadically reported in the United States. However, there is a paucity of molecular data describing the genotypes and haplotypes of this important cestode in domestic ruminant hosts. Ninety-four cysts from the lungs and/or livers of slaughtered beef cattle (76 samples), dairy cows (five
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Wildlife parasitology: sample collection and processing, diagnostic constraints, and methodological challenges in terrestrial carnivores Parasites Vectors (IF 3.2) Pub Date : 2024-03-13 Alicia Rojas, Nina Germitsch, Stephanie Oren, Alireza Sazmand, Georgiana Deak
Wild terrestrial carnivores play a crucial role as reservoir, maintenance, and spillover hosts for a wide parasite variety. They may harbor, shed, and transmit zoonotic parasites and parasites of veterinary importance for domestic hosts. Although wild carnivores are globally distributed and comprise many different species, some living in close proximity to human settlements, only a few studies have
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Expanding the swimmer’s itch pool of the Benelux: a first record of the neurotropic Trichobilharzia regenti and potential link to human infection Parasites Vectors (IF 3.2) Pub Date : 2024-03-13 Ruben Schols, Nathalie Smitz, Ann Vanderheyden, Tine Huyse
Swimmer's itch, an allergic contact dermatitis caused by avian and mammalian blood flukes, is a parasitic infection affecting people worldwide. In particular, avian blood flukes of the genus Trichobilharzia are infamous for their role in swimmer’s itch cases. These parasites infect waterfowl as a final host, but incidental infections by cercariae in humans are frequently reported. Upon accidental infections
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Correction: Geography, phylogeny and host switch drive the coevolution of parasitic Gyrodactylus flatworms and their hosts Parasites Vectors (IF 3.2) Pub Date : 2024-03-13 Hong-Peng Lei, Ivan Jakovlić, Shun Zhou, Xiang Liu, Chuan Yan, Xiao Jin, Bo Wang, Wen-Xiang Li, Gui-Tang Wang, Dong Zhang
Correction: Parasites & Vectors (2024) 17:42 https://doi.org/10.1186/s13071-023-06111-6 Following publication of the original article [1], the following two errors came to the authors' attention: affiliation 5 had been written incorrectly and acknowledgement of 'the Open Fund Project of Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture (2023FB07)' had been omitted from the Funding
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Heartworm disease in domestic dogs in Estonia: indication of local circulation of the zoonotic parasite Dirofilaria immitis farther north than previously reported Parasites Vectors (IF 3.2) Pub Date : 2024-03-12 Maare Mõttus, Paul F. Mõtsküla, Pikka Jokelainen
The mosquito-borne zoonotic parasite Dirofilaria immitis continues to spread northwards in Europe. This parasite can cause potentially life-threatening heartworm disease in dogs and pulmonary dirofilariasis in humans and is, therefore, a major health concern in both the veterinary medicine and human medical fields. This is the first report of D. immitis infections and heartworm disease in the Baltic
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Diversity of Culicoides in the middle belt of Ghana with Implications on the transmission of Mansonella perstans; a molecular approach Parasites Vectors (IF 3.2) Pub Date : 2024-03-12 Linda Batsa Debrah, Joseph F. Arthur, Augustine Yeboah, Dorcas O. Owusu, Ernest Adankwah, Isaac Acheampong, Difery Minadzi, Millicent Lamptey, Vera Serwaa Opoku, Wilfred Aniagyei, Monika M. Vivekanandan, Mohammed K. Abass, Amidu Gawusu, Samuel Wanji, Alexander Y. Debrah, Marc Jacobsen, Richard O. Phillips
Culicoides, also known as biting midges, carry pathogens which include Mansonella perstans. Mansonella perstans is a nematode parasite implicated in a number of disease outcomes. Even though a high prevalence of about 75% M. perstans infection has been recorded in some communities in the middle belt of Ghana, and a wide diversity of Culicoides species has been identified, the exact Culicoides species
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Genetic characterization of schistosome species from cattle in Côte d’Ivoire Parasites Vectors (IF 3.2) Pub Date : 2024-03-12 Jennifer Giovanoli Evack, Jules N. Kouadio, Louise Y. Achi, Bassirou Bonfoh, Eliézer K. N’Goran, Jakob Zinsstag, Jürg Utzinger, Oliver Balmer
Schistosomiasis is a water-based parasitic disease that affects humans, livestock and wild animals. While considerable resources are dedicated to the surveillance, disease mapping, control and elimination of human schistosomiasis, this is not the case for livestock schistosomiasis. Indeed, there are important data and knowledge gaps concerning the species present, population genetic diversity, infection
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Impact assessment of onchocerciasis through lymphatic filariasis transmission assessment surveys using Ov-16 rapid diagnostic tests in Sierra Leone Parasites Vectors (IF 3.2) Pub Date : 2024-03-11 Ibrahim Kargbo-Labour, Mohamed S. Bah, Natalie V. S. Vinkeles Melchers, Abdulai Conteh, Victoria Redwood-Sawyerr, Wilma A. Stolk, Jusufu Paye, Mustapha Sonnie, Amy Veinoglou, Joseph B. Koroma, Mary H. Hodges, Angela M. Weaver, Yaobi Zhang
Onchocerciasis is endemic in 14 of Sierra Leone's 16 districts with high prevalence (47–88.5%) according to skin snips at baseline. After 11 rounds of mass treatment with ivermectin with good coverage, an impact assessment was conducted in 2017 to assess the progress towards eliminating onchocerciasis in the country. A cluster survey was conducted, either integrated with lymphatic filariasis (LF) transmission
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Enzootic stability of tick fever in Holstein calves grazing in a tropical region, subjected to strategic cattle tick control with fluralaner Parasites Vectors (IF 3.2) Pub Date : 2024-03-10 Dina Maria Beltran Zapa, Lidia Mendes de Aquino, Luiz Felipe Monteiro Couto, Luciana Maffini Heller, Igor Maciel Lopes de Morais, Vanessa Ferreira Salvador, Luccas Lourenzzo Lima Lins Leal, Artur Siqueira Nunes Trindade, Warley Vieira de Freitas Paula, Nicolas Jalowitzki de Lima, Lorena Lopes Ferreira, Daniel de Castro Rodrigues, Tom Strydom, Siddhartha Torres, Vando Edésio Soares, Caio Marcio de Oliveira
In 2022, fluralaner was launched on the market for use in the control of the cattle tick Rhipicephalus microplus after showing 100% efficacy in registration trials against the causative agents of cattle tick fever (TFAs). The aim of the present study was to determine whether a strategic control regimen against R. microplus using fluralaner (FLU) in Holstein calves grazing in a tropical region would
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Improving access to melarsomine therapy: treating canine heartworm infection in a high-volume, outpatient community clinic setting Parasites Vectors (IF 3.2) Pub Date : 2024-03-08 Meghan B. Still, Dana Tedesco, Christina Hawkins, Holly Putnam
Models that provide high-quality veterinary care for more affordable prices are emerging, but not well documented outside of wellness and preventative care. Effective treatment guidelines for heartworm disease have been developed by the American Heartworm Society; however, not all owners are able to access treatment due to the high costs associated with sick and emergency care services. To increase
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Construction of luciferase-expressing Neospora caninum and drug screening Parasites Vectors (IF 3.2) Pub Date : 2024-03-08 Fei Wang, Yangfei Xue, Yanqun Pei, Meng Yin, Zhepeng Sun, Zihui Zhou, Jing Liu, Qun Liu
Neospora caninum is an apicomplexan parasite that is particularly responsible for abortions in cattle and neuromuscular disease in dogs. Due to the limited effectiveness of currently available drugs, there is an urgent need for new therapeutic approaches to control neosporosis. Luciferase-based assays are potentially powerful tools in the search for antiprotozoal compounds, permitting the development
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Behavioral responses and life history traits of Taiwanese and Indonesian populations of Aedes aegypti surviving deltamethrin–clothianidin treatment Parasites Vectors (IF 3.2) Pub Date : 2024-03-07 Christina Natalina Silalahi, Aqsa Yasin, Mei-Er Chen, Intan Ahmad, Kok-Boon Neoh
Indoor residual spraying (IRS) capitalizes on the natural behavior of mosquitoes because Aedes aegypti commonly seeks indoor resting sites after a blood meal. This behavior allows mosquitoes to be exposed to insecticide-treated surfaces and subsequently killed. Combinations of deltamethrin and clothianidin with different modes of action have shown promise in IRS, effectively targeting both susceptible
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An improved medium for in vitro studies of female reproduction and oviposition in Schistosoma japonicum Parasites Vectors (IF 3.2) Pub Date : 2024-03-07 Yanmin You, Xu Chen, Lele Huo, Longlong Chen, Gongwen Chen, Mengjie Gu, Cun Yi, Jipeng Wang, Wei Hu
Schistosomiasis is a disease primarily caused by eggs laid by pathogens called schistosomes. Among the schistosome species infecting humans, Schistosoma japonicum possesses the largest fecundity; each adult female produces an average of 3500 eggs per day. The lack of proper culture conditions supporting continuous oviposition in vitro has precluded detailed investigation of mechanisms regulating sexual
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The frequency of kdr and ace-1 alleles in Anopheles gambiae s.l. before and during indoor residual spraying (IRS) implementation and four years after IRS withdrawal in three districts in Atacora, Benin Parasites Vectors (IF 3.2) Pub Date : 2024-03-07 Esdras Mahoutin Odjo, Daniel Impoinvil, Arsène Jacques Y. H. Fassinou, Gil Germain Padonou, Rock Aïkpon, Albert Sourou Salako, André Aimé Sominahouin, Constantin Adoha, Boulais Yovogan, Razaki Osse, Olivier Oussou, Filémon Tokponnon, Virgile Gnanguénon, Ahmed Saadani Hassani, Martin C. Akogbeto
Indoor residual spraying (IRS) was first implemented in the Atacora department, Benin from 2011 to 2012 using bendiocarb (carbamate) followed by annual spraying with pirimiphos-methyl (organophosphate) from 2013 to 2018. Before and after IRS implementation in Atacora, standard pyrethroid insecticide-treated bed nets were the main method of vector control in the area. This study investigated the knockdown
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Circulating cell-free DNA as a biomarker for diagnosis of Schistosomiasis japonica Parasites Vectors (IF 3.2) Pub Date : 2024-03-06 Yu Zhang, Rangjiao Liu, Junhui Li, Hongchang Ma, Wenjuan Bao, Jie Jiang, Chen Guo, Deyong Tan, Xing Cheng, Lizhong Dai, Yingzi Ming
Schistosomiasis, a neglected tropical disease, remains an important public health problem. Although there are various methods for diagnosing schistosomiasis, many limitations still exist. Early diagnosis and treatment of schistosomiasis can significantly improve survival and prognosis of patients. Circulating cell-free (cf)DNA has been widely used in the diagnosis of various diseases. In our study
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Progress in controlling the transmission of schistosome parasites in Southern Ethiopia: the Geshiyaro Project in the Wolaita Zone Parasites Vectors (IF 3.2) Pub Date : 2024-03-06 Birhan Mengsitu, Ewnetu Firdawek Liyew, Melkie Chernet, Geremew Tasew, Santiago Rayment Gomez, Rosie Maddren, Benjamin Collyer, Ufaysa Anjulo, Adugna Tamiru, Kathryn Forbes, Zelalem Mehari, Kebede Deribe, Teshale Yadeta, Mihretab Salasibew, Getachew Tollera, Roy Anderson
This paper describes changes in the prevalence and intensity of schistosome parasite infections in a project integrating mass drug administration (MDA), water, sanitation, and hygiene (WaSH), and behavioral change interventions. The Geshiyaro Project comprises three intervention arms. Arm 1 is subdivided into “Arm 1 pilot” (one district) and Arm 1 (four other districts), both receiving integrated community-wide
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Molecular and entomological surveillance of malaria vectors in urban and rural communities of Benguela Province, Angola Parasites Vectors (IF 3.2) Pub Date : 2024-03-06 Gonçalo Alves, Arlete Dina Troco, Gonçalo Seixas, Rebecca Pabst, Alfredo Francisco, Cani Pedro, Luzala Garcia, José Franco Martins, Sergio Lopes
Malaria is a major public health problem in Angola, with Anopheles gambiae sensu lato (s.l.) and An. funestus s.l. being the primary vectors. This study aimed to clarify the information gaps concerning local Anopheles mosquito populations. Our objectives were to assess their abundance, geographical dispersion, and blood-feeding patterns. We also investigated their insecticide resistance. Molecular
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Lipid metabolism: the potential targets for toxoplasmosis treatment Parasites Vectors (IF 3.2) Pub Date : 2024-03-06 Tian-Yi He, Ye-Tian Li, Zhen-Di Liu, Hao Cheng, Yi-Feng Bao, Ji-Li Zhang
Toxoplasmosis is a zoonosis caused by Toxoplasma gondii (T. gondii). The current treatment for toxoplasmosis remains constrained due to the absence of pharmaceutical interventions. Thus, the pursuit of more efficient targets is of great importance. Lipid metabolism in T. gondii, including fatty acid metabolism, phospholipid metabolism, and neutral lipid metabolism, assumes a crucial function in T. gondii
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Efficiency of fluralaner pour-on in different strategic control protocols against Rhipicephalus microplus on Brangus cattle in a tropical area Parasites Vectors (IF 3.2) Pub Date : 2024-03-06 Guilherme Henrique Reckziegel, Mariana Green de Freitas, Juliane Francielle Tutija, Vinícius Duarte Rodrigues, Dyego Gonçalves Lino Borges, Murilo Damasceno Brunet de Freitas, Tiago Gallina, Welber Daniel Zanetti Lopes, Daniel de Castro Rodrigues, Heitor de Oliveira Arriero Amaral, Tom Strydom, Siddhartha Torres, Fernando de Almeida Borges
The occurrence of higher winter temperatures in Brazilian areas with tropical and highland climates may result in a fifth peak of tick populations during winter in addition to the four generations previously described. Therefore, a strategic control protocol was developed with treatments in two seasons with the objective of controlling the generations of ticks that occur in spring/summer and those
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Characterization of environmental drivers influencing the abundance of Anopheles maculipennis complex in Northern Italy Parasites Vectors (IF 3.2) Pub Date : 2024-03-06 Gianni Gilioli, Francesco Defilippo, Anna Simonetto, Alessandro Heinzl, Manlio Migliorati, Mattia Calzolari, Sabrina Canziani, Davide Lelli, Antonio Lavazza
In Italy, malaria was endemic until the 1970s, when it was declared eradicated by WHO. Nowadays, with the persistence of competent mosquito populations, the effect of climate change, and increased possibility of importing malaria parasites from endemic counties due to growing migration, a malaria resurgence in Italy has become more likely. Hence, enhancing the understanding of the current distribution
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Hepatozoon (Eucoccidiorida: Hepatozoidae) in wild mammals of the Americas: a systematic review Parasites Vectors (IF 3.2) Pub Date : 2024-03-06 Richard Thomas, Adriana Santodomingo, Liliana Saboya-Acosta, Julian F. Quintero-Galvis, Lucila Moreno, Juan E. Uribe, Sebastián Muñoz-Leal
The study of parasites provides insight into intricate ecological relationships in ecosystem dynamics, food web structures, and evolution on multiple scales. Hepatozoon Eucoccidiorida: Hepatozoidae) is a genus of protozoan hemoparasites with heteroxenous life cycles that switch infections between vertebrates and blood-feeding invertebrates. The most comprehensive review of the genus was published 26
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Severe fever with thrombocytopenia syndrome virus infection shapes gut microbiome of the tick vector Haemaphysalis longicornis Parasites Vectors (IF 3.2) Pub Date : 2024-03-05 Yu Sun, Chen Chen, Chenghong Zeng, Qianfeng Xia, Chuanfei Yuan, Hua Pei
Ticks serve as vectors for a diverse array of pathogens, including viruses responsible for both human and livestock diseases. Symbiotic bacteria hold significant potential for controlling tick-borne disease. However, the alteration of tick gut bacterial community in response to pathogen infection has not been analyzed for any tick-borne viruses. Here, the impact of severe fever with thrombocytopenia
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A genotyping array for the globally invasive vector mosquito, Aedes albopictus Parasites Vectors (IF 3.2) Pub Date : 2024-03-04 Luciano Veiga Cosme, Margaret Corley, Thomas Johnson, Dave W. Severson, Guiyun Yan, Xiaoming Wang, Nigel Beebe, Andrew Maynard, Mariangela Bonizzoni, Ayda Khorramnejad, Ademir Jesus Martins, José Bento Pereira Lima, Leonard E. Munstermann, Sinnathamby N. Surendran, Chun-Hong Chen, Kevin Maringer, Isra Wahid, Shomen Mukherjee, Jiannon Xu, Michael C. Fontaine, Elizabet L. Estallo, Marina Stein, Todd
Although whole-genome sequencing (WGS) is the preferred genotyping method for most genomic analyses, limitations are often experienced when studying genomes characterized by a high percentage of repetitive elements, high linkage, and recombination deserts. The Asian tiger mosquito (Aedes albopictus), for example, has a genome comprising up to 72% repetitive elements, and therefore we set out to develop
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Toxoplasma sortilin interacts with secretory proteins and it is critical for parasite proliferation Parasites Vectors (IF 3.2) Pub Date : 2024-03-04 Chenghuan Li, Ning Jiang, Yize Liu, Yiwei Zhang, Ran Chen, Ying Feng, Xiaoyu Sang, Qijun Chen
The human sortilin protein is an important drug target and detection marker for cancer research. The sortilin from Toxoplasma gondii transports proteins associated with the apical organelles of the parasite. In this study, we aimed to determine the intracellular localization and structural domains of T. gondii sortilin, which may mediate protein transportation. Approaches to the functional inhibition
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Contribution of Anopheles gambiae sensu lato mosquitoes to malaria transmission during the dry season in Djoumouna and Ntoula villages in the Republic of the Congo Parasites Vectors (IF 3.2) Pub Date : 2024-03-02 Jacques Dollon Mbama Ntabi, Espoir Divin Malda Bali, Abel Lissom, Romaric Akoton, Jean Claude Djontu, Georges Missontsa, Freisnel Hermeland Mouzinga, Marcel Tapsou Baina, Luc Djogbenou, Cyrille Ndo, Charles Wondji, Ayola Akim Adegnika, Arsène Lenga, Steffen Borrmann, Francine Ntoumi
Mosquitoes belonging to the Anopheles gambiae sensu lato complex play a major role in malaria transmission across Africa. This study assessed the relative importance of members of An. gambiae s.l. in malaria transmission in two rural villages in the Republic of the Congo. Adult mosquitoes were collected using electric aspirators from June to September 2022 in Djoumouna and Ntoula villages and were
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Time of exposure and assessment influence the mortality induced by insecticides against metabolic resistant mosquitoes Parasites Vectors (IF 3.2) Pub Date : 2024-03-02 Olukayode G. Odufuwa, John Bradley, Safina Ngonyani, Ahmadi Bakari Mpelepele, Isaya Matanila, Joseph B. Muganga, Rune Bosselmann, Ole Skovmand, Zawadi Mageni Mboma, Sarah Jane Moore
Increasing metabolic resistance in malaria vector mosquitoes resulted in the development of insecticide-treated nets (ITNs) with active ingredients (AI) that target them. Bioassays that accurately measure the mortality induced by these AIs on ITNs are needed. Mosquito metabolic enzyme expression follows a circadian rhythm. Thus, this study assessed (i) influence of the time of day of mosquito exposure
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Multi-omics data elucidate parasite-host-microbiota interactions and resistance to Haemonchus contortus in sheep Parasites Vectors (IF 3.2) Pub Date : 2024-03-01 Simone Cristina Méo Niciura, Tainã Figueiredo Cardoso, Adriana Mercia Guaratini Ibelli, Cintia Hiromi Okino, Bruno Gabriel Andrade, Magda Vieira Benavides, Ana Carolina de Souza Chagas, Sergio Novita Esteves, Alessandro Pelegrine Minho, Luciana Correia de Almeida Regitano, Cedric Gondro
The integration of molecular data from hosts, parasites, and microbiota can enhance our understanding of the complex biological interactions underlying the resistance of hosts to parasites. Haemonchus contortus, the predominant sheep gastrointestinal parasite species in the tropics, causes significant production and economic losses, which are further compounded by the diminishing efficiency of chemical
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Control of Rhipicephalus microplus on taurine cattle with fluralaner in a subtropical region Parasites Vectors (IF 3.2) Pub Date : 2024-03-01 Tiago Gallina, Camila dos Santos Lagranha, Giancarlo Bilo, Cristiano Malavolta, Lorena Lopes Ferreira, Fernando de Almeida Borges, Daniel de Castro Rodrigues, Tom Strydom, Siddartha Torres, Emmanuel Arnhold, Welber Daniel Zanetti Lopes
In Rio Grande do Sul, Brazil, a region with a subtropical climate, Rhipicephalus microplus is present in taurine cattle raised for beef and milk. In addition, ticks resistant to multiple acaricides are present in this region. Recently, fluralaner (isoxazoline) was launched on the market. Thus, there is a need to evaluate the effects of fluralaner for the control of R. microplus on taurine cattle. In
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Molecular phylogeny of the family Rhabdiasidae (Nematoda: Rhabditida), with morphology, genetic characterization and mitochondrial genomes of Rhabdias kafunata and R. bufonis Parasites Vectors (IF 3.2) Pub Date : 2024-03-01 Jia-Lu Zeng, Hui-Xia Chen, Xue-Feng Ni, Jia-Yi Kang, Liang Li
The family Rhabdiasidae (Nematoda: Rhabditida) is a globally distributed group of nematode parasites, with over 110 species parasitic mainly in amphibians and reptiles. However, the systematic position of the family Rhabdiasidae in the order Rhabditida remains unsolved, and the evolutionary relationships among its genera are still unclear. Moreover, the present knowledge of the mitochondrial genomes
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Phytochemical analysis and anthelmintic activity of Combretum mucronatum leaf extract against infective larvae of soil-transmitted helminths including ruminant gastrointestinal nematodes Parasites Vectors (IF 3.2) Pub Date : 2024-03-01 François Ngnodandi Belga, Patrick Waindok, Marie-Kristin Raulf, Jonathan Jato, Emmanuel Orman, Steffen Rehbein, Verena Spiegler, Eva Liebau, Andreas Hensel, Dieudonné Ndjonka, Christina Strube
Soil-transmitted helminths (STH) infect more than a quarter of the world’s human population. In the absence of vaccines for most animal and human gastrointestinal nematodes (GIN), treatment of infections primarily relies on anthelmintic drugs, while resistance is a growing threat. Therefore, there is a need to find alternatives to current anthelmintic drugs, especially those with novel modes of action
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Anopheles gambiae larvae’s ability to grow and emerge in water containing lethal concentrations of clothianidin, acetamiprid, or imidacloprid is consistent with cross-resistance to neonicotinoids Parasites Vectors (IF 3.2) Pub Date : 2024-03-01 Marilene Ambadiang, Caroline Fouet, Fred Ashu, Calmes Bouaka, Véronique Penlap-Beng, Colince Kamdem
For decades, various agrochemicals have been successfully repurposed for mosquito control. However, preexisting resistance caused in larval and adult populations by unintentional pesticide exposure or other cross-resistance mechanisms poses a challenge to the efficacy of this strategy. A better understanding of larval adaptation to the lethal and sublethal effects of residual pesticides in aquatic
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Field evaluation of an automated mosquito surveillance system which classifies Aedes and Culex mosquitoes by genus and sex Parasites Vectors (IF 3.2) Pub Date : 2024-03-01 María I. González-Pérez, Bastian Faulhaber, Carles Aranda, Mark Williams, Pancraç Villalonga, Manuel Silva, Hugo Costa Osório, Joao Encarnaçao, Sandra Talavera, Núria Busquets
Mosquito-borne diseases are a major concern for public and veterinary health authorities, highlighting the importance of effective vector surveillance and control programs. Traditional surveillance methods are labor-intensive and do not provide high temporal resolution, which may hinder a full assessment of the risk of mosquito-borne pathogen transmission. Emerging technologies for automated remote
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Effect of the mitochondrial uncoupling agent BAM15 against the Toxoplasma gondii RH strain and Prugniaud strain Parasites Vectors (IF 3.2) Pub Date : 2024-03-01 Zhendi Liu, Jiao Mo, Yetian Li, Siyang Liu, Qingyuan Zeng, Jili Zhang
Toxoplasmosis is a zoonotic disease caused by the infection of the protozoa Toxoplasma gondii (T. gondii), and safe and effective therapeutic drugs are lacking. Mitochondria, is an important organelle that maintains T. gondii survival, however, drugs targeting mitochondria are lacking. The cytotoxicity of BAM15 was detected by CCK-8 and the in vitro effects of BAM15 was detected by qPCR, plaque assay
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Blood-feeding patterns of Culex pipiens biotype pipiens and pipiens/molestus hybrids in relation to avian community composition in urban habitats Parasites Vectors (IF 3.2) Pub Date : 2024-02-29 Rody Blom, Louie Krol, Melissa Langezaal, Maarten Schrama, Krijn B. Trimbos, Daan Wassenaar, Constantianus J. M. Koenraadt
Culex pipiens sensu stricto (s.s.) is considered the primary vector of Usutu virus and West Nile virus, and consists of two morphologically identical but behaviourally distinct biotypes (Cx. pipiens biotype pipiens and Cx. pipiens biotype molestus) and their hybrids. Both biotypes are expected to differ in their feeding behaviour, and pipiens/molestus hybrids are presumed to display intermediate feeding
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A combined amplicon approach to nematode polyparasitism occurring in captive wild animals in southern China Parasites Vectors (IF 3.2) Pub Date : 2024-02-28 Hongyi Li, Zhengjiu Ren, Weijian Wang, Fei Shen, Jingyi Huang, Chuyue Wang, Jinzhi Lu, Xi Pan, Lihua Xiao, Yaoyu Feng, Dongjuan Yuan
Gastrointestinal tract (GIT) nematodes prefer to live in the intestines of wild animals, causing damage and even death, and posing a zoonotic risk. The polyparasitism of GIT nematodes results in the complex dynamics of the nematode communities that occur naturally in wild animals. However, the nematode community in captive wild animals is poorly understood. We combined microscopic examination and amplicon
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Community composition of black flies during and after the 2020 vesicular stomatitis virus outbreak in Southern New Mexico, USA Parasites Vectors (IF 3.2) Pub Date : 2024-02-27 Madelin J. Whelpley, Lawrence H. Zhou, Jeremy Rascon, Bailey Payne, Brett Moehn, Katherine I. Young, Chad E. Mire, Debra P. C. Peters, Luis L. Rodriguez, Kathryn A. Hanley
Vesicular stomatitis virus (VSV), a vector-borne pathogen of livestock, emerges periodically in the western US. In New Mexico (NM), US, most cases occur close to the Rio Grande River, implicating black flies (Simulium spp.) as a possible vector. In 2020, VS cases were reported in NM from April to May, although total black fly abundance remained high until September. We investigated the hypothesis that
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An integrated data analysis reveals distribution, hosts, and pathogen diversity of Haemaphysalis concinna Parasites Vectors (IF 3.2) Pub Date : 2024-02-27 Jing Liu, Xiao-Yu Han, Run-Ze Ye, Qing Xu, Xiao-Yang Wang, Ze-Hui Li, Yi Sun, Ke Song, Bao-Yu Wang, Shan-Shan Wang, Jin-Yue Liu, Lin Zhao, Wu-Chun Cao
Haemaphysalis concinna, carrying multiple pathogens, has attracted increasing attention because of its expanded geographical range and significant role in disease transmission. This study aimed to identify the potential public health risks posed by H. concinna and H. concinna-associated pathogens. A comprehensive database integrating a field survey, literature review, reference book, and relevant websites
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Pyrethroid resistance status and co-occurrence of V1016G, F1534C and S989P mutations in the Aedes aegypti population from two dengue outbreak counties along the China-Myanmar border Parasites Vectors (IF 3.2) Pub Date : 2024-02-27 Li Chen, Kemei Zhou, Jun Shi, Yuting Zheng, Xiaotao Zhao, Qingyun Du, Yingkun Lin, Xaioxiong Yin, Jinyong Jiang, Xinyu Feng
Over the past two decades, dengue fever (DF) has emerged as a significant arboviral disease in Yunnan province, China, particularly in the China-Myanmar border area. Aedes aegypti, an invasive mosquito species, plays a crucial role in transmitting the dengue virus to the local population. Insecticide-based vector control has been the primary tool employed to combat DF, but the current susceptibility
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IxPopDyMod: an R package to write, run, and analyze tick population and infection dynamics models Parasites Vectors (IF 3.2) Pub Date : 2024-02-26 Myles Stokowski, David Allen
Given the increasing prevalence of tick-borne diseases, such as Lyme disease, modeling the population and infection dynamics of tick vectors is an important public health tool. These models have applications for testing the effects of control methods or climate change on tick populations. There is an established history of tick population models, but code for them is rarely shared, especially not in
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ParSCo: celebrating 10 years of a unique parasitology summer course Parasites Vectors (IF 3.2) Pub Date : 2024-02-26 Filipe Dantas-Torres, Marcos Antonio Bezerra-Santos, Jairo Alfonso Mendoza-Roldan, Riccardo Paolo Lia, Livia Perles, Juan Pedro Barrera, Renata Fagundes-Moreira, Mariaelisa Carbonara, Antonio Varcasia, Emanuele Brianti, Georgiana Deak, Alicia Rojas, Guadalupe Miró, Petr Volf, Gad Baneth, Domenico Otranto
ParSCo (Parasitology Summer Course) is an intense, 1-week-long summer course organized by the Parasitology Unit of the Department of Veterinary Medicine, University of Bari, Italy, with the support of the World Association for the Advancement of Veterinary Parasitology (WAAVP), the European Veterinary Parasitology College (EVPC) and Parasites and Vectors. The course, which is conducted in southern
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Impact of SumiLarv® 2MR on Aedes aegypti larvae: a multicenter study in Brazil Parasites Vectors (IF 3.2) Pub Date : 2024-02-26 Josiane Nogueira Müller, Allan Kardec Ribeiro Galardo, Ana Paula Sales de Andrade Corrêa, Maria de Lourdes da Graça Macoris, Maria Alice Varjal de Melo-Santos, Mitsue Maia Nakazawa, Ademir Jesus Martins, José Bento Pereira Lima
Aedes aegypti is associated with dengue, Zika, and chikungunya transmission. These arboviruses are responsible for national outbreaks with severe public health implications. Vector control is one of the tools used to prevent mosquito proliferation, and SumiLarv® 2MR is an alternative commercial product based on pyriproxyfen for larval/pupal control. In this study, the residual effectiveness of SumiLarv®
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Frequency of Anaplasma phagocytophilum, Borrelia spp., and coinfections in Ixodes ricinus ticks collected from dogs and cats in Germany Parasites Vectors (IF 3.2) Pub Date : 2024-02-23 Julia Probst, Andrea Springer, Volker Fingerle, Christina Strube
Changing geographical and seasonal activity patterns of ticks may increase the risk of tick infestation and tick-borne pathogen (TBP) transmission for both humans and animals. To estimate TBP exposure of dogs and cats, 3000 female I. ricinus from these hosts were investigated for Anaplasma phagocytophilum and Borrelia species. qPCR inhibition, which was observed for ticks of all engorgement stages
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An innovative strategy for deworming dogs in Mediterranean areas highly endemic for cystic echinococcosis Parasites Vectors (IF 3.2) Pub Date : 2024-02-23 Martina Nocerino, Paola Pepe, Antonio Bosco, Elena Ciccone, Maria Paola Maurelli, Franck Boué, Gérald Umhang, Justine Pellegrini, Samia Lahmar, Yousra Said, Smaragda Sotiraki, Panagiota Ligda, AbdElkarim Laatamna, Giorgio Saralli, Orlando Paciello, Maria Chiara Alterisio, Laura Rinaldi
Cystic echinococcosis (CE), caused by the larval stage of Echinococcus granulosus sensu lato, is a zoonotic parasitic disease of economic and public health importance worldwide, especially in the Mediterranean area. Canids are the main definitive hosts of the adult cestode contaminating the environment with parasite eggs released with feces. In rural and peri-urban areas, the risk of transmission to
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Toxocara canis infection in multiple types of animals: ophthalmological and pathological observations Parasites Vectors (IF 3.2) Pub Date : 2024-02-23 Shuxin Zheng, Limei Sun, Li Huang, Yue Xie, Xiaoyan Ding
Human ocular toxocariasis (OT), caused by pet roundworm Toxocara canis (Nematoda Ascaridoidea), is a worldwide ocular parasitic infection that poses a severe threat to eyesight, especially in school-aged children. However, the infection process and pathological mechanism of Toxocara are difficult to study in the human body. This study was designed to explore long-term ocular manifestations in different
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Data release: targeted systematic literature search for tick and tick-borne pathogen distributions in six countries in sub-Saharan Africa from 1901 to 2020 Parasites Vectors (IF 3.2) Pub Date : 2024-02-22 Abigail A. Lilak, David B. Pecor, Graham Matulis, Alexander M. Potter, Rachel N. Wofford, Mary F. Kearney, Stephanie Mitchell, Fatima Jaradat, Arisa Kano, Dawn M. Zimmerman, James M. Hassell, Bersissa Kumsa, Maureen Kamau, Yvonne-Marie Linton, Michael E. von Fricken
Surveillance data documenting tick and tick-borne disease (TBD) prevalence is needed to develop risk assessments and implement control strategies. Despite extensive research in Africa, there is no standardized, comprehensive review. Here we tackle this knowledge gap, by producing a comprehensive review of research articles on ticks and TBD between 1901 and 2020 in Chad, Djibouti, Ethiopia, Kenya, Tanzania
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Human cercarial dermatitis (HCD) in the UK: an overlooked and under-reported nuisance? Parasites Vectors (IF 3.2) Pub Date : 2024-02-22 Orla Kerr, Alexandra Juhász, Sam Jones, J. Russell Stothard
Human cercarial dermatitis (HCD) is a clinical disease typically caused by skin-penetrative larvae of avian schistosomes. Its geographical epidemiology is firmly tied with that of infected freshwater intermediate snail hosts. To better understand the current distribution of HCD and its level of nuisance in the UK, we undertook a systematic literature review. Following PRIMSA guidelines, PubMed and
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Simultaneous detection of seven bacterial pathogens transmitted by flies using the reverse line blot hybridization assay Parasites Vectors (IF 3.2) Pub Date : 2024-02-22 Yonghua Ma, Qingli Niu, Xiaolin Sun, Yuanyuan Li, Huitian Gou, Zexiang Wang, Beibei Song
Traditional methods for detecting insect-borne bacterial pathogens are time-consuming and require specialized laboratory facilities, limiting their applicability in areas without access to such resources. Consequently, rapid and efficient detection methods for insect-borne bacterial diseases have become a pressing need in disease prevention and control. We aligned the ribosomal 16S rRNA sequences of