样式: 排序: IF: - GO 导出 标记为已读
-
Anti-cancer activity of Moringa oleifera Lam. seed oil on oral cancer Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-03-15 Moumita Das, Jatindra Nath Mohanty, Sanat Kumar Bhuyan, Ruchi Bhuyan
Despite recent advances in the diagnosis and treatment of oral cancer, relative survival rates have not changed significantly. Moringa oleifera (M. oleifera) Lam. is one such plant with its anticancer properties being proved in its leaves, stem, flowers but no studies are yet reported proving the anticancer property of its seed oil on oral cancer. This study aimed to evaluate the anti-proliferative
-
Clinical and biological significance of microRNA-127 and microRNA-138 expression in women with breast cancer: response to treatment and survival impact Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-03-13 Ghada M. Nasr, Mohamed F. Elshal, Eman Abdel-Ghani Gobran, Mohamed Younis Nasr, Eman A. E. Badr, Reham Ahmed Abdel-Aziz, Amal Abdel-Aziz, Hind S. AboShabaan
Genetic and epigenetic changes characterize the multi-step process of breast carcinogenesis. It is believed that abnormal microRNA (miRNA) expression has a role in the onset and progression of breast cancer. This study aimed to examine the link between miRNA-127 and miRNA-138 and metastasis, tumor invasion, and apoptosis in Egyptian women with breast cancer, as well as their correlation with its molecular
-
Molecular approach for identification and validation of Eurycoma longifolia, Labisia pumila, and Orthosiphon stamineus in herbal products Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-03-12 Siti Nor Amira Mohd Azli, Adibah Abu Bakar, Salwa Shahimi, Bryan Raveen Nelson, Azi Azeyanty Jamaludin, Jameel R. Al-Obaidi
Eurycoma longifolia (E. longifolia), Labisia pumila (L. pumila), and Orthosiphon stamineus (O. stamineus) are popular species known for their therapeutic properties. An increase in local demand for herbal products makes them susceptible to adulteration, which poses a risk to their safety and efficacy. Current identification methods, such as organoleptic, microscopic, and macroscopic analysis, need
-
Flexural performance of rapid-hardening concrete (RHC) beams with tension lap splice Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-03-12 Mohamed Hussein El Fakhrany, Amal el-Zamrawi, Wael Ibrahim, Alaa Sherif
Rapid-hardening concrete (RHC) is a specialized type of concrete that gains strength at an accelerated rate, allowing for faster construction and reduced project timelines. The use of RHC in structural applications, such as in beams subjected to flexural loads, has gained significant attention due to its potential for improving construction efficiency. This study focuses on the flexural performance
-
Neuroprotective effect of bromelain on BDNF-TRKB signalling pathway in chronic unpredictable stress-induced depression model Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-03-11 Rajeshwari Parasuraman, Dheepthi Jayamurali, Nivedita Manoharan, Sathya Narayanan Govindarajalu
Bromelain is a mixture of protease enzyme extract from the fruit or stem of the pineapple plant. It has a wide range of biological actions, and it is most commonly used as an anti-inflammatory agent. This study was designed to investigate the antidepressant effect of bromelain on chronic unpredictable stress (CUS)-induced depression in rat models by targeting various molecular mechanisms. We studied
-
Assessment of glypican-3 immune expression in ameloblastoma, ameloblastic fibroma, ameloblastic carcinoma (pilot study) Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-03-11 Nayl Ahmed Al-ezzi Al-Malahy, Shaymaa Omar Zayed, Heba Ahmed Saleh
Odontogenic tumors a variety of benign and malignant lesions developed exclusively in the jaws. They are known to have variable clinical behaviors and different histological features. The development of odontogenic tumors is attributed to alterations in some genetic and biological molecules. The aim of this study is to assess Glypican-3 immune expression in different groups of odontogenic neoplasms
-
Robust congregation influences of AB-PINACA and MDMB-4en-PINACA inhalation on neurobehavioral and cardiac disorders in mice Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-03-09 Manar A. Ahmad, Sherien Salah Ghaleb, Dalia Abd Elwahab Hassan, Souty M. Z. Sharkawi, Asmaa K. Abdelghany, Asmaa Mahmoud Mostafa, Randa M. Hassan, Ahmed G. Sobhi Abdalla
A novel category of unusual cannabinoid substances was created to serve as marijuana alternatives due to its widespread availability, low price, pleasurable effects, and difficulty to be detected in regular urine testing for drugs, although more potential for abuse, toxicity, and behavioral alterations can result. It is more hazardous to multiple organ systems and has higher CB1 and CB2 receptor affinities
-
Efficacy improvement of tri-serotypes vaccine for Salmonella using nanomaterial-based adjuvant in chicken Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-02-29 Hazem M. Ibrahim, Gina M. Mohammed, Rafik Hamed Sayed, Hisham A. Elshoky, Heba Elsayed Elzorkany, Shaimaa Abdelall Elsaady
This study aimed to develop a vaccine for controlling salmonellosis, a zoonotic disease affecting both humans and chicken, by employing Fe2O3 ferrous iron oxide (FNPs), silicon dioxide (SiNPs), carboxymethyl chitosan (C.CS NPs), and FNPs-chitosan (FCNPs) nanocomposite as immunological adjuvants. The immune response of vaccinated chicken was assessed through ELISA and challenge tests. The hydrodynamic
-
Immunoinformatic and molecular docking approaches: siRNA prediction to silence cell surface binding protein of monkeypox virus Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-02-22 Rahatul Islam, Asif Shahriar, Muhammad Ramiz Uddin, Nour Fatema
Monkeypox virus (MPV), an endemic pathogen in Africa, shares clinical similarities with smallpox. Recent reports indicate a concerning increase in the number of MPV cases detected outside its endemic region, highlighting the emergence of a multi-country outbreak. Given the importance of the cell surface-binding protein E8L in facilitating viral attachment to host cells, this study aimed to identify
-
Impact behavior of spark plasma sintered Ti–Al–Mo/TiN composites: a finite element analysis approach using Abaqus CAE Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-02-22 Samson Olaitan Jeje, Tawanda Marazani, Mxolisi Brendon Shongwe
The utilization of Finite Element Analysis (FEA) has emerged as a crucial methodology in the field of structural and elasticity analysis, facilitating researchers in their understanding of material responses to diverse thermal or structural loads. This study investigates the utilization of FEA to simulate the Impact characteristics of titanium composites, with specific emphasis on the Charpy impact
-
Computer aided design of novel antibiotic drug candidate against multidrug resistant strains of Salmonella typhi from pyridine-substituted coumarins Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-02-12 Philip John Ameji, Adamu Uzairu, Gideon Adamu Shallangwa, Sani Uba
The rising cases of resistance to existing antibiotics by Salmonella typhi, has made the development of novel drug candidates a necessity. In this study, a data set of antibacterial pyridine substituted coumarins were subjected to Virtual Screening against SipA effector protein of the bacterium. The compounds were geometry-optimized using Semi-empirical (pm3) method in Spartan 14 software, docked against
-
The association of p21, inhibin, and Tob-1 expression with the clinicopathological characteristics of benign and malignant colorectal lesions Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-02-11 Mona Moussa, Aya Mohamed Abdullah, Mohieldin Magdy Youssef, Dalal Elwi, Noha Said Helal
Worldwide, colorectal cancer (CRC) is the third most common cancer and the second most common cause of cancer-related deaths. p21, inhibin, and Tob-1 are tumor suppressors that play a role in the development and progression of several cancers, however, their role in CRC is not well-established. This study aims to evaluate the expression of these proteins by immunohistochemistry and correlate their
-
Overcoming Klebsiella pneumoniae antibiotic resistance: new insights into mechanisms and drug discovery Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-02-04 Tran Xuan Ngoc Huy
Due to antibiotic overuse, numerous organisms have evolved multidrug resistance, a global health crisis. Klebsiella pneumoniae (K. pneumoniae) causes respiratory, biliary, and urinary infections. It initially impacts individuals with impaired immune systems. The treatment of K. pneumoniae clones poses significant challenges, highlighting the need for new, more effective pathogen control methods. Our
-
Comparison of four DNA barcoding loci to distinguish between some Apiaceae family species Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-01-29 Shaimaa A. Abdelaziz, Khaled A. M. Khaled, Rania A. A. Younis, Magdy A. Al-Kordy, Fotouh M. El-Domyati, Mona M. Moghazee
The Apiaceae family is among the most significant plant families because it contains both beneficial and poisonous plants. Due to their morphological similarity, these harmless and lethal species are frequently confounded. Cumin, fennel, and anise are the most prevalent members of the family Apiaceae in Egypt. Members of this family are routinely used as medical surrogates, so it is crucial that they
-
Proanthocyanidins supplemented diet alter anti-aging-markers and improved lifespan in Drosophila melanogaster model Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-01-27 Mohammed Sani Jaafaru, Suleiman Alhaji Muhammad, Zainab Kasim Mohammed, Yakubu Aliyu, Ahmad Faizal Abdull Razis
It is unequivocally believed that phenolics and flavonoids from fruits and vegetables hold robust prevention potentials against age-related disease development through their abundant hydroxyl groups. This study explored the potential neuromuscular enhancement and anti-aging effects of dietary supplemented proanthocyanidins-rich fraction from Tamarindus indica on Drosophila melanogaster model. One-
-
Ultrasound-guided percutaneous nephrolithotomy versus conventional c-arm-guided percutaneous nephrolithotomy: a prospective randomized comparative study Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-01-23 Akram A. Elmarakbi, Ahmed M. Gaber Mohamed, Amr M. Massoud, Ahmed Abdelbary, Rabie M. Ibrahim
Ultrasound guidance for renal access in percutaneous nephrolithotomy (PCNL) is a safe, effective, and low-cost procedure. The current study compared the safety and effectiveness of ultrasound-guided PCNL (US-PCNL) for renal stone therapy versus fluoroscopy-guided PCNL (FL-PCNL) in prone position. Successful puncture was attained in all cases in both groups. Unlike fluoroscopy, US guidance reduced the
-
Insecticidal activity and possible modes of action of secondary metabolites of some fungal strains and wild plants as natural pesticides against Spodoptera frugiperda Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-01-20 Reda R. H. Abdullah, A. H. Abd El-Wahab, Samira A. Abd El-Salam
The fall armyworm (FAW), Spodoptera frugiperda, is an invasive and destructive pest to certain strategic crops, especially maize in Egypt. This research was conducted mainly to obtain secondary metabolites from some wild plants and fungal strains, use them in controlling FAW, and investigate their mode of action. The ethyl acetate extracts of Cladosporium cladosporioides and Verticillium lecanii, as
-
Molecular characterization of the camel nasal botfly, Cephalopina titillator (Diptera: Oestridae) Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-01-18 Mona G. Shaalan, Sherif Hamed Farghaly, Emad I. Khater, Mohamed A. Kenawy, Enas Hamdy Ghallab
Larval stages of the camel nasal botfly, Cephalopina titillator (Diptera: Oestridae), rank among the top obligate endoparasites causing nasopharyngeal myiasis. Such infestations have adverse effects on camel health, reducing their economic value. The current study’s objective is to assess the applicability of PCR using partial regions of the COI mtDNA and 28S rRNA gene sequences to identify, classify
-
Assessment of the protective and ameliorative impact of quercetin nanoparticles against neuronal damage induced in the hippocampus by acrolein Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-01-15 Samia M. Sanad, Safaa E. Nassar, Reham Farouk
The most frequent kind of dementia in the senior population is Alzheimer's disease (AD). Antioxidant quercetin has a low bioavailability. The bioavailability of quercetin nanoparticles was demonstrated to be higher. Acrolein is thought to be the strongest unsaturated aldehyde. Acrolein contributes to the propagation of oxidative damage and thus the aetiology of AD. This study aimed to investigate histopathological
-
Phenolic-rich fraction of green tea attenuates histamine-mediated cardiopulmonary toxicity by inhibiting Cox-2/NF-κB signaling pathway and regulating oxidant/antioxidant balance Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-01-12 Eman I. Hassanen, Shaimaa Kamel, Marwa Y. Issa, Wafaa A. Mohamed, Hayam A. Mansour, Mahmoud A. Mahmoud
Histamine (HIS) has a substantial impact on the development of numerous allergic disorders including asthma. Antihistamines mostly target histamine receptor-1 alone, so it is not entirely effective in the treatment of allergic diseases. In the current investigation, we examine the growing evidence for novel therapeutic strategies that aim to treat histamine-mediated cardiopulmonary toxicity with the
-
Use of agro-industrial bio-waste for the growth and production of a previously isolated Bacillus thuringiensis strain Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-01-04 Hister M. M. dos Santos, Camila de S. Varize, Camilla A. S. Valença, Fábio C. A. Dossi, Marcus V. de Aragão Batista, Roberta P. M. Fernandes, Patricia Severino, Eliana B. Souto, Silvio S. Dolabella, Marcelo da C. Mendonça, Sona Jain
Bacillus thuringiensis (Bt) is a widely used biopesticide. The bioinsecticide based on Bt is obtained by fermentation, but the substrates currently used for its production constitute ingredients of high commercial value. In this context, the use of agro-industrial residues as substrates is an alternative to make the fermentation process viable on a large scale, in addition to minimizing environmental
-
Machine learning-driven optimization of enterprise resource planning (ERP) systems: a comprehensive review Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-01-04 Zainab Nadhim Jawad, Villányi Balázs
In the dynamic and changing realm of technology and business operations, staying abreast of recent trends is paramount. This review evaluates the progress in the development of the integration of machine learning (ML) with enterprise resource planning (ERP) systems, revealing the impact of these trends on the ERP optimization. In recent years, there has been a significant advancement in the integration
-
Solubility enhancing lipid-based vehicles for artemether and lumefantrine destined for the possible treatment of induced malaria and inflammation: in vitro and in vivo evaluations Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-01-04 Onyinyechi Lydia Ugorji, Ikechukwu Virgilius Onyishi, Julie Ngozichukwuka Onwodi, Christiania Moji Adeyeye, Uzochukwu Gospel Ukachukwu, Nicholas Chinedu Obitte
The lipid self-emulsifying system has been advanced as a promising delivery vehicle for improving the solubility and bioavailability of artemether and lumefantrine. However, the observed kinetic instability (propensity of lumefantrine to rapid crystallisation from nano-scale droplets) in aqueous acid has impelled some researchers to incorporate surfactants/solubilizers in the dissolution medium prior
-
Comparative study between radiation exposure in common urological procedures Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-01-02 Akrm A. Elmarakbi, Ali Korany Elnoiry, Nashaat Deiab, Amr M. Lotfy
Fluoroscopy has become essential to urological surgery since advancement of endourology. Fluoroscopy use has increased, placing urologists as well as staff members at risk for occupational radiation exposure and related dangers. This study compared radiation exposure for staff personnel in percutaneous nephrolithotomy (PCNL), ureteroscopy (URS) and extracorporeal shock wave lithotripsy (ESWL). Then
-
Anti-Alzheimer potential of Solanum lycopersicum seeds: in vitro, in vivo, metabolomic, and computational investigations Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2024-01-02 Hussain T. Bakhsh, Omnia Hesham Abdelhafez, Abeer H. Elmaidomy, Hanan F. Aly, Eman A. Younis, Mubarak A. Alzubaidi, Naseh A. Algehainy, Faisal H. Altemani, Mohammed Majrashi, Faisal Alsenani, Gerhard Bringmann, Usama Ramadan Abdelmohsen, Fatma Alzahraa Mokhtar
Solanum lycopersicum Linn. (Tomato, Family Solanaceae) is one of the fruits that are most consumed worldwide. The current research intends to emphasise the possibility of positive and therapeutic effects of S. lycopersicum seed extract (SLSE) on Alzheimer's disease's neurodegeneration effects being reversed in a study utilising rats exposed to aluminium chloride. Investigations were done on the cholinesterase
-
Correlation analysis between polymorphism of leptin and IGFI genes and body measurements in Barki and Farafra sheep Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-12-20 Ahmed M. Darwish, Mohamed A. Abdelhafez, Zeinab G. Abdel-Hamid, Sarah I. Othman, Ibrahim E. Mohamed, Ahmed A. Allam
Growth performance, which can be evaluated using various body measurements, is crucial for providing red meat for human consumption. This study aims to improve the growth performance of sheep by identifying the different genotypes of leptin and IGFI genes associated with higher body measurements. In this study, we collected blood samples from Barki (n = 30) and Farafra (n = 30) sheep, and measured
-
Synthesis and efficacy of cinnamon oil formulations and their sustainable release against common house mosquito larvae Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-12-19 Hesham A. Mahran, Shawky M. Aboelhadid, Khaled M. Hassan
Control of mosquitoes is considered an essential public health priority. This study was designed to estimate the larvicidal activity of two formulations of Cinnamomum zeylanicum EO for controlling Culex pipiens larvae. The prepared formulations were a nanoemulsion of cinnamon (CNE), cinnamon (CN) alone and ordinary cinnamon essential oil mixed with sesame oil (CSO). The cinnamon + sesame oil (CSO)
-
Fabrication and evaluation of smart pH/thermo dual-responsive injectable intratumoral in situ depot hydrogels for controlled 5-FU delivery Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-12-19 Samiullah Khan, Bangul Khan, Huan Li
5-FU has multiple applications in various cancers but has limitations owing to its shorter half-life and rapid metabolism. In this study, injectable intratumoral gels were developed to enhance 5-FU concentrations in tumor vicinity. Sterile tunable poly (N-isopropylacrylamide)-based pH/thermo dual-sensitive self-assembled and in situ crosslinkable injectable depot gels with low viscous grade of chitosan
-
Phenetic and cladistic analyses of Boraginaceae Juss. Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-12-17 Usama K. Abdel-Hameed, Wael A. Obaid, Walaa A. Hassan, Najla A. Al Shaye, Salma S. Abd El-Ghany
The systematics of family Boraginaceae draw attention of many botanists for many years. The current study's primary goals are to clarify phenetic and phylogenetic relationships within Boraginaceae according to morphology and molecular characteristics and to evaluate the morphological characters that can be applied in systematics of Boraginaceae. The macromorphological characters of 39 species, 2 subspecies
-
Nanotoxicological profiles of clinically approved nanoplatforms Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-12-16 Christian Isalomboto Nkanga
Nanoparticles (NPs) engineering offers great opportunities to produce versatile materials for multiple applications in medicine, including drug delivery and bioimaging. Successful development of nanomedicines up to the clinical level is evidence that nanotechnology has made gigantic strides in addressing health problems. This review briefly discusses the toxicological data from selected clinically
-
COVID-19-related health literacy and preparedness to what may come: a cross-sectional study Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-12-11 Hebatallah Ahmed Mohamed Moustafa, Amira B. Kassem
Since the first report of COVID-19 in 2019, information released has been fast and vast. Health literacy focuses on individual skills to obtain, process, and understand health information and services necessary to make informed health decisions. Increasing the level of health literacy can be addressed by the provision of high-quality, trustworthy, easy-to-access, and easy-to-understand information
-
Metabolites of Trichoderma harzianum re-balance T-reg/Th-17 cytokine axis in epileptic rats Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-12-04 Mohamed A. Alblihed
Recurrent seizure is synchronous neuronal network hyperexcitation. Even though many anti-epileptic drugs (AEDs) are available, but have several drawbacks, including multiple drug interactions, suboptimal response rates, significant adverse effects, and a narrow therapeutic index. Trichoderma is a biocontrol agent which maintains stress-related gene expression to adapt to unstable environmental conditions
-
The association of claudin-18 and androgen receptor expression in prostatic carcinoma: an immunohistochemical study Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-11-30 Heba M. Rashad, Hanan Ahmed, Kareem Ali El Attar, Eman A. Saad
Claudin-18 (CLDN18) is a recently identified anticancer therapeutic target with promising results for various gastrointestinal malignancies. The role of CLDN18 in prostatic carcinoma has not been investigated. The aim of this study was to investigate CLDN18 and androgen receptor (AR) expression in prostatic carcinoma and to link these findings with other clinicopathological characteristics. This retrospective
-
QSAR modeling, molecular docking, dynamic simulation and ADMET study of novel tetrahydronaphthalene derivatives as potent antitubercular agents Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-11-29 Anguraj Moulishankar, T. Sundarrajan
Tuberculosis is an air-borne contagious disease caused by slow-growing Mycobacterium tuberculosis (Mtb). According to Global Tuberculosis Report 2022, 1.6 million people were infected by tuberculosis in 2021. The continuing spread of drug-resistant tuberculosis (TB) is one of the most difficult challenges to control the tuberculosis. So new drug discovery is essential to the treatment of tuberculosis
-
CD72 gene expression in children suffering from primary immune thrombocytopenia and its correlation with the disease activity Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-11-28 Yasmen A. Mohamed, Dalia S. Morgan, Mostafa M. ELsaghier, Rehab M. Abd-Elkareem
Immune thrombocytopenia is a condition in which the immune system attacks platelets, leading to a low platelet count. CD72 is a co-receptor found on B cells during all developmental stages except those of plasma cells. Activation of CD72 promotes B cell growth and differentiation. We aimed to investigate the expression and role of CD72 in pediatric immune thrombocytopenia, as well as its correlation
-
SRAP and IRAP revealed molecular characterization and genetic relationships among cowpea (Vigna unguiculata L.) irradiated by gamma-ray Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-11-28 Clara R. Azzam, Fadia M. Sultan, Mokhtar S. Rizk, Mohamed Z. S. Ahmed, Shafik D. Ibrahim, Ahmed Noureldeen, Esmat F. Ali, Hadeer Darwish, Khaled Adly M. Khaled
Cowpea is a high-protein legume that can be grown in many environments. Gamma radiation can modify plant metabolism and growth. An experiment was conducted to determine the effect of different gamma-ray doses on cowpea yield and growth. The results showed that gamma radiation had a significant effect on cowpea yield and growth, with the highest yields and growth rates observed at lower doses. Higher
-
Sterols and flavonoids in strawberry calyx with free radical scavenging, anti-inflammatory, and molecular dynamic study Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-11-13 Amal M. El‑Feky, Ahmed A. El-Rashedy
The phytochemical constitution and biological capabilities of Fragaria ananassa's calyx have not been extensively investigated before. Consequently, the research study pointed for characterization, isolation, and identification of the sterols and flavonoids as the major active constituents in the calyx of F. ananassa and evaluation for their impacts as free radicals scavenger and anti-inflammatory
-
Variable cross-sectional effect on bi-directional blades–tower–soil–structure dynamic interaction on offshore wind turbine subject to wind–wave loads Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-11-11 Mostafa A. El Absawy, Zakaria Elnaggar, Hesham H. Ibrahim, M. H. Taha
This study introduces a numerical model designed to simulate interactions occurring between a wind turbine's tower and the surrounding soil, as well as between the nacelle, blades, and the surrounding environment. This simulation accounts for both fore–aft and side-to-side movements. To describe these interactions, the model leverages the Euler–Lagrange equations. It calculates wave loads utilizing
-
Numerical modelling of traffic-induced dynamic loading on a two-story residential building Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-11-09 Henok Marie Shiferaw, Girma Moges Teshager, Solomon Aynalem Hailu, Tadiyos Marie Shiferaw
This paper presents a numerical modelling procedure of dynamic loading due to traffic on a two-story residential building. In developing countries cities and towns, poor quality narrow road sections with high traffic density are common. In such cases, ground vibration due to traffic could be higher and lightweight buildings located closer are exposed to traffic-induced dynamic loading. Design codes
-
The alleviative efficacy of sildenafil and chrysin against zinc oxide nanoparticles-provoked hepatic and blood toxicity: role of MyD88/NF-κB1/TNF-α pathway Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-11-08 Mahitab M. Nageeb, Marwa Abdel-Moniem Amer, Doaa M. Hendawy, Sabah Mohamed Hanafy, Maha Saad Elmenshawi, Gena M. Elmakromy, Dena Mohamed Naguib Abdel Moawed
Zinc oxide nanoparticles are nanoparticles of metal oxide with semiconductor properties and proved many noxious effects on the mammalian cell. Sildenafil, a phosphodiesterase inhibitor, and chrysin, one of the flavonoids, proved to have anti-inflammatory and anti-oxidative stress effects. 48 rats were grouped into 8 groups equally. 1. (Control group) received normal diet and NaOH was added to water
-
Empagliflozin versus Sitagliptin as add-on dual therapy in Egyptian patients with type 2 diabetes inadequately controlled with Metformin: a 12-week randomized, open-label, parallel-group trial Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-11-08 Haitham G. Zakaraia, Heba F. Salem, Mostafa A. A. Mostafa, Ahmed M. Ali, Hoda M. Rabea
Diabetes is one of the world’s most widespread conditions, and diabetic patients are among the most likely to engage in fierce battles with this chronic disease. Which group should be added-on as a dual therapy for Egyptian patients with type 2 diabetes and inadequate glycemic management, HbA1c ≥ 7.0% and ≤ 10% (≥ 53 and ≤ 86 mmol/mol), following not less than 3 months of metformin and diet therapy
-
Efficacy of polyherbal formulation along with standard care of treatment in early recovery of COVID-19 patients: a randomized placebo-controlled trial Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-11-07 Abhishek Arun, Saumya Subramanian, Divya Kanchibhotla
The coronavirus disease-2019 (COVID-19) pandemic crisis has affected millions of people worldwide. The emergence of mutant strains one after the other, breakthrough infections post-vaccination and reinfection of the virus have made it difficult to fight the pandemic and bring an end to it. Naturally available compounds with an array of phytochemicals and potent antiviral properties can provide an alternate
-
Hydrogen peroxide enhances transforming growth factor beta-2 induced epithelial–mesenchymal transition of ARPE-19 cells Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-11-07 Brijesh Gelat, Pooja Rathaur, Pooja Malaviya, Binita Patel, Abhay R. Vasavada, S. R. Kaid Johar
In the pathophysiology of the retina, the epithelial–mesenchymal transition and oxidative stress play key roles. To find a relationship between oxidative stress and diabetic retinopathy or proliferative retinopathy, we used an in-silico approach. We also used an in vitro investigation to examine the synergistic effect of transforming growth factors-β2 (TGFβ2) and hydrogen peroxide (H2O2) on the ep
-
A modified model for laser-cornea interaction following the ablation effect in the laser eye-surgery Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-11-06 Ibrahim Abdelhalim, Omnia Hamdy, Aziza Ahmed Hassan, Salwa Abdelkawi, Salah Hassab Elnaby
Laser corneal reshaping is a successful treatment of many refraction disorders. However, some physical demonstrations for the laser interaction with cornea are not fully explained. In the current paper, we present a modified model to precisely investigate the ablation threshold, the ablation rate and the physical/chemical mechanisms in that action. The model discusses the possible photochemical reaction
-
Immunogenicity of extracellular proteins of Flavobacterium covae in Ictalurus punctatus Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-11-06 Mohamed Sayed, Rania Omar
Columnaris disease, instigated by Gram-negative Flavobacterium covae (F. covae), is a dreadful disease of many different genera of freshwater fish with alarmingly high mortality rates. Ictalurus punctatus (I. punctatus) is extremely prone to this disease. Despite the terrible implications of this disease, very little is known about how the host and the bacterium's virulence factor interact. Secreted
-
Polydatin nanoparticles attenuate oxidative stress and histopathological changes in streptozotocin model of diabetic nephropathy: targeting Nrf2/HO-1/NF-κβ signaling pathways Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-11-06 Manal Abdul-Hamid, Sanaa R. Galaly, Hanaa M. Mohamed, Fatma Mostafa, Adel Abdel-Moneim
One of the most prevalent and serious side effects of diabetes mellitus is diabetic nephropathy, which is characterized by abnormalities in kidney structure that can occur before kidney function declines. Up to 90% of persons with diabetic nephropathy and 40% of adults with severe diabetic nephropathy are unaware that they have kidney disease. Through Nrf2/HO-1/NF κβ/TNF α signaling pathways, biochemical
-
Carbapenemase producing Enterobacterales clinical isolates from a tertiary care hospital in Egypt Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-11-03 Inas El Defrawy, Dalia Salem, Ghada Ali, Doaa Gamal, Ehab El Dabaa, Manal Diab, Sohair Abd-Elmaguid Alyan, Marwa K. Sallam
Carbapenem resistant Enterobacterales (CRE) is on the rise globally, triggering a significant health threat and a substantial concern for infection control management. We aimed to detect and characterize carbapenemases producing Enterobacterales (CPE) clinical isolates over a period of nearly one-year duration in Theodor Bilharz Research Institute, a tertiary care hospital in Egypt through molecular
-
Immunohistochemical assessment of the potential behavior of glandular odontogenic cyst and inflammatory periodontal cyst using E-cadherin and N-cadherin Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-11-02 Heba Ahmed Saleh, Dina M. Makawi, Asmaa Emad El-Din Mohamed Rashad
This study is done to evaluate the immunohistochemical expression of E-cadherin and N-cadherin in glandular odontogenic cysts (GOC), inflammatory periodontal (IPDL) cysts, and dental follicles (DF), and if there is a correlation with their biological behavior GOC, IPDL cysts, and DF cases were collected and investigated by immunohistochemistry. The area percent of immunoexpressed markers was calculated
-
Endothelium-dependent vasorelaxation effects of F5 fraction of Crinum amabile chloroform extract Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-11-01 Chung Pin Lim, Yam Mun Fei, Mohd. Zaini Asmawi, VoonKin Chin, Nurul-Hayah Khairuddin, Yoke Keong Yong, Mukhtar Gambo Lawal, Rusliza Basir
Vascular dysfunction can lead to many health problems including hypertension and heart disease. The complexities of vascular dysfunction and vascular disorder-related diseases have prompted the search for many new biologically active compounds in the efforts of resolving the problems. Previous studies have shown that Amaryllidaceae alkaloids exert multiple biological activities, including the vasorelaxation
-
A hybrid B-spline collocation technique for the Caputo time fractional nonlinear Burgers’ equation Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-10-27 Mohammad Tamsir, Deependra Nigam, Neeraj Dhiman, Anand Chauhan
This study proposes an efficient and stable technique based on new hybrid B-spline (HB-spline) functions for the numerical treatment of the Caputo time fractional nonlinear Burgers’ (TFNB) equation. The time derivative is discretized using the definition of the Caputo derivative, whereas HB-spline functions are used to discretize the spatial derivatives. The Rubin–Graves technique is used to linearize
-
Regulation of epithelial-mesenchymal transition in retinal pigment epithelium and its associated cellular signaling cascades: an updated review Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-10-26 Brijesh Gelat, Pooja Malaviya, Pooja Rathaur, Krupali Trivedi, Priya Chaudhary, Binita Patel, Kaid Johar, Rahul Gelat
The epithelial-mesenchymal transition (EMT) affects the retinal pigment epithelium's natural homeostasis. According to observations from around the world, numerous oculopathies, including proliferative vitreoretinopathy (PVR), diabetic retinopathy (DR), and other macular degenerative illnesses such as age-related macular degeneration (AMD), have been linked to the epithelial-mesenchymal transition
-
The modified homotopy perturbation method and its application to the dynamics of price evolution in Caputo-fractional order Black Scholes model Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-10-24 Adedapo Ismaila Alaje, Morufu Oyedunsi Olayiwola, Kamilu Adewale Adedokun, Joseph Adeleke Adedeji, Asimiyu Olamilekan Oladapo, Yunus Olanrewaju Akeem
Following a financial loss in trades due to lack of risk management in previous models from market practitioners, Fisher Black and Myron Scholes visited the academic setting and were able to mathematically develop an option pricing equation named the Black–Scholes model. In this study, we address the solution of a Caputo fractional-order Black–Scholes model using an analytic method named the modified
-
Correction: Efficacy of threshold inspiratory muscle trainer versus diaphragmatic plus pursed lip breathing in occupational COPD Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-10-23 Marwa Mohammed, Sherin Mehani, Azza Abdel Aziz, Maha Fathy Mohamed, Nesreen El Nahas
Correction : Beni-Suef Univ J Basic Appl Sci (2023) 12:73 https://doi.org/10.1186/s43088-023-00409-1 Following the publication of the original article [1] we were informed that the second author's name “Sherin Hassan” is incorrect. The correct name is “Sherin Mehani”. The correct name is shown in the author list of this Correction. The original article has been revised accordingly. Mohammed M, Mehani
-
Characterization and optimization of clove oil-loaded nanomicelles for the possible topical use of bacterial infection-led atopic dermatitis Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-10-16 Gulam Mustafa, Rand Abdullah Almohsen, Munira Motlaq Alotaibi, Mohammed Majed Alotaibi, Ruaa Majed Alotaibi, Ahmed Farag El Kirdasy, Farhan R. Khan, Nahed S. Alharthi, Abdulkarim S. Binshaya, Faisal Alotaibi, Md Salahuddin Ansari
Atopic dermatitis is an abnormal skin condition that impacts a significant number of people in the US, with an estimated 9.6 million children and 16.5 million adults being affected by it. The study aimed to characterize and optimize clove oil-based nanomicelles for the possible topical use of bacterial infection-led atopic dermatitis. Clove oil-loaded nanomicelles were produced and carefully analyzed
-
A prototype variable corresponding to the proportion of ischemia for the comparison between robotic and open partial nephrectomy: a meta-analysis accompanied by sensitivity analysis Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-10-14 Sotirios Artsitas, Dimitrios Artsitas, Irene Koronaki, Konstantinos G. Toutouzas, George C. Zografos
The primary objective of this study involves the formulation of a novel variable, derived from initial data related to ischemia duration and operative time in partial nephrectomies. The aim was to determine the proportion of ischemia for the comparison between robotic and open approaches in terms of their relative ischemic requirements. The literature search was conducted from August 2022 to June 2023
-
Study of Cosavirus, Salivirus, and Bufavirus viruses in children with acute gastroenteritis Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-10-09 Omnia Ahmed Mohamed Salem, Maysaa El Sayed Zaki, Ahmed G. Elsayed, Ahmed Zaki Mohamed Hassan, Eman Hamdy Mohamed
Acute gastroenteritis (AGE) in children represents a health problem. Besides common enteric viruses such as rotavirus and adenovirus, new viruses such as cosavirus, salivirus, and bufavirus may be associated with AGE. The objective of the study was to detect cosavirus, salivirus, and bufavirus viruses in children below 5 years with acute gastroenteritis by the use of real-time polymerase chain reaction
-
The rising burden of chronic kidney diseases in patients with diabetes Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-10-09 Ensaf Y. Almomani, Huda Y. Almomani, Sayer Al-Azzam, Ahmad Qablan, Abass Al-Momany
The prevalence of chronic kidney diseases (CKD) is higher in patients with diabetes. The American diabetes association (ADA) provides components of diabetes care, treatments, and guidelines to diagnose diabetic patients at risk of CKD. Herein we followed the ADA diagnosis guidelines to identify the Type 2 Diabetes mellitus (T2DM) patients at risk of CKD which is underestimated in the region. The study
-
Artificial intelligence in diagnosis and management of Huntington’s disease Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-10-05 Neel Parekh, Anjali Bhagat, Binith Raj, Raunak Singh Chhabra, Harpal Singh Buttar, Ginpreet Kaur, Seema Ramniwas, Hardeep Singh Tuli
Huntington’s disease is one of the rare neurodegenerative diseases caused because of genetic mutation of the Huntingtin gene. The major hallmarks of the condition include motor impairment, cognitive decline, and psychiatric symptoms. With no cure and only symptomatic treatments available, early detection and personalized therapy are warranted for managing the disease effectively. Artificial Intelligence
-
Hydromagnetic flow of micropolar nanofluids with co-effects of thermal radiation and chemical reaction over an inclined permeable stretching surface Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-09-26 O. A. Ajala, P. Adegbite
Many investigations have been conducted by researchers across the globe to examine the behavior of fluids with respect to the influence of some constituent parameters and novel results have been obtained. However, the combined effect of thermal radiation and chemical reaction on micropolar nanofluid flow over an inclined stretching surface has not been well elucidated. This article, therefore, employed
-
Evaluation of the therapeutic potentials of extract fractions of Vernonia calvoana on streptozotocin-induced diabetic rats: approach through in silico, in vitro and in vivo studies Beni-Suef Univ. J. Basic Appl. Sci. Pub Date : 2023-09-25 Iwara Arikpo Iwara, Victor S. Ekam, Eve O. Mboso, Michael Oko Odey, Ofem E. Eteng, Joe Enobong Eshiet, Godwin Oju Igile, Friday Effiong Uboh, Mbeh Eteng Ubana
Diabetes is a serious metabolic disorder and many medicinal plants are used in traditional medicine to manage it. This study aimed to evaluate the therapeutic effects of Vernonia calvoana (V. calvoana) extract fractions on streptozotocin-induced diabetic rat models. In this study, we first investigated the binding affinity of ligands from extracts of V. calvoana crystal structure proteins using a molecular