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Research progress on the mechanism of common inflammatory pathways in the pathogenesis and development of lymphoma Ann. Med. (IF 4.4) Pub Date : 2024-03-15 Aorong Shi, Fen Yun, Lin Shi, Xia Liu, Yongfeng Jia
In recent years, the incidence and mortality rates of lymphoma have gradually increased worldwide. Tumorigenesis and drug resistance are closely related to intracellular inflammatory pathways in ly...
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Exploring the molecular mechanisms of asthma across multiple datasets Ann. Med. (IF 4.4) Pub Date : 2024-03-15 Lianshan Guo, Enhao Huang, Tongting Wang, Yun Ling, Zhengzhao Li
Asthma, a prevalent chronic respiratory disorder, remains enigmatic, notwithstanding considerable advancements in our comprehension. Continuous efforts are crucial for discovering novel molecular t...
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Rapid cycle deliberate practice: application in forceps simulation training for gynecology and obstetrics residents Ann. Med. (IF 4.4) Pub Date : 2024-03-13 Xiaoxue Wang, Zixuan Song, Xueting Chen, Yangzi Zhou, Yingze Lou, Tong Liu, Dandan Zhang
Rapid Cycle Deliberate Practice (RCDP) has gained prominence in recent years as an innovative teaching method in simulation-based training for adult and pediatric emergency medical skills. However,...
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G-CSF + plerixafor versus G-CSF alone mobilized hematopoietic stem cells in patients with multiple myeloma and lymphoma: a systematic review and meta-analysis Ann. Med. (IF 4.4) Pub Date : 2024-03-12 Yuyao Li, Xia Qiu, Yupeng Lei, Ruixi Zhou
The combination of granulocyte-colony stimulating factor (G-CSF) and plerixafor is one of the approaches for hematopoietic stem cell mobilization in patients with multiple myeloma (MM), non-Hodgkin...
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Acceptability of two mobile applications to support cross-sectoral, person-centred and empowering stroke rehabilitation – a process evaluation Ann. Med. (IF 4.4) Pub Date : 2024-03-11 Mille Nabsen Marwaa, Susanne Guidetti, Charlotte Ytterberg, Hanne Kaae Kristensen
To evaluate the acceptability of two co-designed mobile applications Mit Sygehus [a knowledge-based solution] and Genoptræn.dk [a self-training solution] to support a cross-sectoral, person-centred...
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Impact of physical activity on preeclampsia and angiogenic markers in the Finnish Genetics of Pre-eclampsia Consortium (FINNPEC) cohort Ann. Med. (IF 4.4) Pub Date : 2024-03-11 Noora Jaatinen, Eeva Ekholm, FINNPEC, Hannele Laivuori, Tiina Jääskeläinen
Effect of physical activity in pregnancy on preeclampsia (PE) and angiogenic markers is not well understood. We studied the association of physical activity and PE in a case-control setting and ass...
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A systematic review of artificial intelligence-powered (AI-powered) chatbot intervention for managing chronic illness Ann. Med. (IF 4.4) Pub Date : 2024-03-11 Moh Heri Kurniawan, Hanny Handiyani, Tuti Nuraini, Rr Tutik Sri Hariyati, Sutrisno Sutrisno
Utilizing artificial intelligence (AI) in chatbots, especially for chronic diseases, has become increasingly prevalent. These AI-powered chatbots serve as crucial tools for enhancing patient commun...
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Efficacy of the COVID-19 vaccination in patients with asymptomatic or mild illness during the Omicron epidemic in Guangzhou: a multi-centre retrospective cohort study Ann. Med. (IF 4.4) Pub Date : 2024-03-11 Yuanda Xu, Xuetao Kong, Weiqing Huang, Zijing Liang, Jinkun Huang, Yimin Li, Nuofu Zhang, Dan Liu, Wenwei Guo, Jiang Mei
Despite the widespread administration of coronavirus disease 2019 (COVID-19) vaccines, the impact on patients with asymptomatic to mild illness remains unclear. Here, we aimed to assess the efficac...
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The psychosocial impact of eye-gaze assistive technology on everyday life of children and adults Ann. Med. (IF 4.4) Pub Date : 2024-03-05 Maria Andreassen, Maria Borgestig, Helena Hemmingsson
This study investigates the psychosocial impact of eye-gaze assistive technology (EGAT) in both children and adults with long-term experience using eye-gaze assistive technology in everyday life, a...
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Knowledge, experiences, and perceptions of medications for opioid use disorder among Black Kentuckians Ann. Med. (IF 4.4) Pub Date : 2024-03-05 Paris B. Wheeler, Brittany Miller-Roenigk, Jasmine Jester, Danelle Stevens-Watkins
Opioid overdoses have continued to increase at higher rates among Black Americans compared to people from other racial groups. Despite demonstrated effectiveness of MOUD in reducing risk of opioid ...
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A comprehensive evaluation of risk factors for mortality, infection and colonization associated with CRGNB in adult solid organ transplant recipients: a systematic review and meta-analysis Ann. Med. (IF 4.4) Pub Date : 2024-03-05 Siyu Gao, Xiaoli Huang, Xiaolin Zhou, Xiangcheng Dai, Jing Han, Yandong Chen, Hongliang Qiao, Yi Li, Yifan Zhou, Ting Wang, Huiqing He, Qiang Liu, Shenjie Tang
The burden of carbapenem-resistant gram-negative bacteria (CRGNB) among solid organ transplant (SOT) recipients has not been systematically explored. Here, we discern the risk factors associated wi...
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Tenecteplase versus alteplase for the treatment of acute ischemic stroke: a meta-analysis of randomized controlled trials Ann. Med. (IF 4.4) Pub Date : 2024-03-05 Jian Huang, Hui Zheng, Xianfeng Zhu, Kai Zhang, Xiaofeng Ping
Tenecteplase, a modified variant of alteplase with greater fibrin specificity and longer plasma half-life, may have better efficacy and safety than alteplase in patients with acute ischemic stroke ...
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Gastrin-releasing peptide receptor (GRPR) as a novel biomarker and therapeutic target in prostate cancer Ann. Med. (IF 4.4) Pub Date : 2024-03-05 Honghu Zhang, Lin Qi, Yi Cai, Xiaomei Gao
Aim: This comprehensive review aims to explore the potential applications of Gastrin-releasing peptide receptor (GRPR) in the diagnosis and treatment of prostate cancer. Additionally, the study inv...
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Insomnia is related to long-term atrial fibrillation recurrence following radiofrequency ablation Ann. Med. (IF 4.4) Pub Date : 2024-02-29 Rui-bin Li, Ji-dong Zhang, Xiao-ran Cui, Wei Cui
Atrial fibrillation (AF), the most common cardiac arrhythmia, presents significant health challenges, and the intricate connection between insomnia and AF has garnered substantial attention. This c...
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Advanced Parkinson’s disease treatment patterns in Italy: an observational study interim analysis Ann. Med. (IF 4.4) Pub Date : 2024-02-21 Fabrizio Stocchi, Paolo Barone, Roberto Ceravolo, Maria Francesca De Pandis, Leonardo Lopiano, Nicola Modugno, Alessandro Padovani, Manuela Pilleri, Alessandro Tessitore, Mario Zappia
Oral levodopa remains the mainstay of treatment for Parkinson’s disease (PD). However, as PD progresses, response to treatment may fluctuate. Managing fluctuations can be demanding for clinicians a...
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Development and initial testing of mindful journey: a digital mindfulness-based intervention for promoting recovery from Substance use disorder Ann. Med. (IF 4.4) Pub Date : 2024-02-21 Corey R. Roos, Brian Kiluk, Kathleen M. Carroll, Jonathan B. Bricker, Chung Jung Mun, Margarita Sala, Megan Kirouac, Elena Stein, Maya John, Robert Palmer, Andrew DeBenedictis, Jena Frisbie, Angela M. Haeny, Declan Barry, Lisa M. Fucito, Sarah Bowen, Katie Witkiewitz, Hedy Kober
There is a great unmet need for accessible adjunctive interventions to promote long-term recovery from substance use disorder (SUD). This study aimed to iteratively develop and test the initial fea...
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Associations of thyroid feedback quantile-based index with diabetes in euthyroid adults in the United States and China Ann. Med. (IF 4.4) Pub Date : 2024-02-21 Heng Wan, Genfeng Yu, Yajun He, Siyang Liu, Xingying Chen, Yuqi Jiang, Hualin Duan, Xu Lin, Lan Liu, Jie Shen
We aimed to investigate the associations between thyroid hormone sensitivity indices and diabetes in euthyroid adults in the United States and China.2296 euthyroid adults from the NHANES in the Uni...
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Tai Chi training as a primary care plan for the prevention and management of hypertension: an opinion and positioning article Ann. Med. (IF 4.4) Pub Date : 2024-02-19 Ting Zhang, Shuman Yang, Wei Liu, Qingping Bai, Song Gao
Hypertension is a prevalent chronic condition worldwide that can impact patients’ quality of life. Oral antihypertensive drugs are widely used to manage high blood pressure, primarily by regulating...
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Propyl gallate induces human pulmonary fibroblast cell death through the regulation of Bax and caspase-3 Ann. Med. (IF 4.4) Pub Date : 2024-02-19 Woo Hyun Park
Propyl gallate (PG) has been found to exert an inhibitory effect on the growth of different cell types, including lung cancer cells. However, little is known about the cytotoxicological effects of ...
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LASSO-derived model for the prediction of lean-non-alcoholic fatty liver disease in examinees attending a routine health check-up Ann. Med. (IF 4.4) Pub Date : 2024-02-16 Chiao-Lin Hsu, Pin-Chieh Wu, Fu-Zong Wu, Hsien-Chung Yu
Lean individuals with non-alcohol fatty liver disease (NAFLD) often have normal body size but abnormal visceral fat. Therefore, an alternative to body mass index should be considered for prediction...
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Tuberculosis (TB) treatment challenges in TB-diabetes comorbid patients: a systematic review and meta-analysis Ann. Med. (IF 4.4) Pub Date : 2024-02-12 Mahnoor Khattak, Anees ur Rehman, Tuba Muqaddas, Rabia Hussain, Muhammad Fawad Rasool, Zikria Saleem, Mesfer Safar Almalki, Samar Adel Alturkistani, Shuruq Zuhair Firash, Oseid Mohammed Alzahrani, Ammar Abdulraheem Bahauddin, Safa Almarzooky Abuhussain, Muath Fahmi Najjar, Hossameldeen Mahmoud Ali Elsabaa, Abdul Haseeb
The Directly Observed Treatment-Short Course (DOTS) Programme was implemented by WHO and includes a combination of four anti-tuberculosis (TB) drugs (isoniazid, pyrazinamide, ethambutol and rifampi...
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Analysis of airway structural parameters in Han Chinese adults: a prospective cross-sectional study Ann. Med. (IF 4.4) Pub Date : 2024-02-16 Yan Liu, Jun Teng, Jian Mei, Chao Chen, Qian-qian Xu, Cui Zhou, Kang-li Deng, Hong-wu Wang
Establishing reference ranges for central airway parameters and exploring their influencing factors in Han Chinese non-smoking adults.This prospective cross-sectional study was conducted on Han Chi...
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Clinical characteristics of complete responders versus non-complete responders to omalizumab, benralizumab and mepolizumab in patients with severe asthma: a long-term retrospective analysis Ann. Med. (IF 4.4) Pub Date : 2024-02-16 Maria Basagaña, Carlos Martínez-Rivera, Clara Padró, Ignasi Garcia-Olivé, Mimar Martínez-Colls, Juan Navarro, Laura Pardo, Paula Cruz, Gloria Cardona Peitx, Lídia Carabias, Albert Roger, Jorge Abad, Antoni Rosell
Some patients with severe asthma may benefit from treatment with biologics, but evidence has been mostly collected from randomized controlled trials (RCTs), in which patients’ characteristics are d...
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Advances in targeted therapy of cholangiocarcinoma Ann. Med. (IF 4.4) Pub Date : 2024-02-15 Yuhang Li, Jianfeng Yu, Yujing Zhang, Chuang Peng, Yinghui Song, Sulai Liu
Cholangiocarcinoma (CCA) is a malignant tumor originating in the bile duct and its branching epithelium. Due to its high heterogeneity, there are no specific clinical indications at the early stage...
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A multicenter feasibility randomized controlled trial using a virtual reality application of pain neuroscience education for adults with chronic low back pain Ann. Med. (IF 4.4) Pub Date : 2024-02-14 Ryan McConnell, Elizabeth Lane, Grace Webb, Dana LaPeze, Hailey Grillo, Julie Fritz
Chronic low back pain (CLBP) is a highly prevalent condition among adults and is correlated to high levels of pain, high disability, and lower quality of life. Pain neuroscience education (PNE) hel...
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Efficacy of intraoperative systemic lidocaine on quality of recovery after laparoscopic colorectal surgery: a randomized controlled trial Ann. Med. (IF 4.4) Pub Date : 2024-02-12 Wenjun Lin, Ying Yang, Yifen Zhuo, Chunlin Qiu, Yanhua Guo, Yusheng Yao
Many clinical trials have demonstrated the benefits of intraoperative systemic lidocaine administration in major abdominal surgeries. We tested the hypothesis that systemic lidocaine is associated ...
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Fibrillatory wave amplitude and thromboembolic risk in non-anticoagulated patients with atrial fibrillation Ann. Med. (IF 4.4) Pub Date : 2024-02-13 Arto Relander, Samuli Jaakkola, Hilla Virri, Eelis Niemelä, Tuija Vasankari, Ilpo Nuotio, K. E. Juhani Airaksinen, Tuomas Kiviniemi
The benefit of oral anticoagulation in atrial fibrillation (AF) is well established for patients at elevated stroke risk, but less clear for those at intermediate risk. We investigated whether anal...
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Dual role for microbial short-chain fatty acids in modifying SIV disease trajectory following anti-α4β7 antibody administration Ann. Med. (IF 4.4) Pub Date : 2024-02-14 Samuel D. Johnson, Nageswara Pilli, Jianshi Yu, Lindsey A. Knight, Maureen A. Kane, Siddappa N. Byrareddy
Human Immunodeficiency Virus (HIV)/Simian Immunodeficiency Virus (SIV) infection is associated with significant gut damage, similar to that observed in patients with inflammatory bowel disease (IBD...
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Associations of nirmatrelvir-ritonavir treatment with death and clinical improvement in hospitalized patients with COVID-19 during the Omicron wave in Beijing, China: a multicentre, retrospective cohort study Ann. Med. (IF 4.4) Pub Date : 2024-02-14 Xiaobo Han, Chenglong Li, Xin Yuan, Junchang Cui, Zhihai Han, Jiguang Meng, Weiguo Zhao, Fei Xie, Kaifei Wang, Yuhong Liu, Guoxin Muo, Na Xi, Mengli Zheng, Rentao Wang, Kun Xiao, Wei Chen, Junchen Xiong, Dahui Zhao, Xinxin Zhang, Xinjie Han, Haibo Cheng, Zhongkuo Yu, Yinghan Shi, Wuxiang Xie, Lixin Xie
The effectiveness of nirmatrelvir–ritonavir has mainly been shown in non-hospitalized patients with mild-to-moderate coronavirus disease 2019 (COVID-19). The real-world effectiveness of nirmatrelvi...
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The role of molecular imaging in detecting fibrosis in Crohn’s disease Ann. Med. (IF 4.4) Pub Date : 2024-02-12 Ali S. Alyami, Yahia Madkhali, Naif A. Majrashi, Bandar Alwadani, Meaad Elbashir, Sarra Ali, Wael Ageeli, Hesham S. El-Bahkiry, Abdullah A. Althobity, Turkey Refaee
Fibrosis is a pathological process that occurs due to chronic inflammation, leading to the proliferation of fibroblasts and the excessive deposition of extracellular matrix (ECM). The process of lo...
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The influence of sleep factors and dietary habits on the disease pattern of ulcerative colitis patients with long and short disease courses – a multicentre cross-sectional analysis Ann. Med. (IF 4.4) Pub Date : 2024-02-12 Mingyue Guo, Gechong Ruan, Xueli Ding, Yanbo Yu, Linglin Tian, Jun Shen, Xiaoyin Bai, Lingjuan Jiang, Weiyang Zheng, Huijun Shu, Xiaolan Zhang, Hong Yang
Ulcerative colitis (UC) is a disease characterized by chronic relapsing-remitting inflammatory disorders and is associated with environmental changes.To explore the disease patterns of Chinese UC p...
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Effectiveness of digital tools for smoking cessation in Asian countries: a systematic review Ann. Med. (IF 4.4) Pub Date : 2024-02-12 Khang Wen Goh, Long Chiau Ming, Yaser Mohammed Al-Worafi, Ching Siang Tan, Andi Hermansyah, Inayat Ur Rehman, Zahid Ali
The use of tobacco is responsible for many preventable diseases and deaths worldwide. Digital interventions have greatly improved patient health and clinical care and have proven to be effective fo...
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Development and validation of HBV surveillance models using big data and machine learning Ann. Med. (IF 4.4) Pub Date : 2024-02-10 Weinan Dong, Cecilia Clara Da Roza, Dandan Cheng, Dahao Zhang, Yuling Xiang, Wai Kay Seto, William C. W. Wong
The construction of a robust healthcare information system is fundamental to enhancing countries’ capabilities in the surveillance and control of hepatitis B virus (HBV). Making use of China’s rapi...
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Age shock index and age-modified shock index are valuable bedside prognostic tools for postdischarge mortality in ST-elevation myocardial infarction patients Ann. Med. (IF 4.4) Pub Date : 2024-02-07 Shan Wang, You Zhang, Datun Qi, Xianpei Wang, Zhongyu Zhu, Wei Yang, Muwei Li, Dayi Hu, Chuanyu Gao
The incidence of mortality is considerable after ST-elevation myocardial infarction (STEMI) hospitalization; risk assessment is needed to guide postdischarge management. Age shock index (SI) and ag...
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Cerebral white matter burden is linked to cognitive function in patients undergoing hemodialysis Ann. Med. (IF 4.4) Pub Date : 2024-02-07 Tsai-Shan Wu, Ping-Hsun Wu, Hsiu-Fen Lin, Wen-Ching Chen, Teng-Hui Huang, Ming-Yen Lin, Yun-Shiuan Chuang, Fan-Pei Gloria Yang, Yi-Wen Chiu, Jer-Ming Chang, Mei-Chuan Kuo, Yi-Ting Lin
Chronic kidney disease is related to neurodegeneration and structural changes in the brain which might lead to cognitive decline. The Fazekas scale used for assessing white matter hyperintensities ...
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Efficacy of dupilumab and risk factors for dupilumab-induced hypereosinophilia in severe asthma: a preliminary study from China Ann. Med. (IF 4.4) Pub Date : 2024-02-05 You Li, Zhenan Deng, Junjie Wen, Changxing Ou, Xiaomin Cen, Yongkang Liao, Qingling Zhang, Jiaxing Xie
Dupilumab has been approved for the treatment of severe asthma with type 2 inflammation by inhibiting interleukin (IL)-4 and IL-13 signaling. However, dupilumab-induced hypereosinophilia (HE) has b...
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Bowel health, defecation patterns and nutrient intake following adoption of a vegan diet: a randomized-controlled trial Ann. Med. (IF 4.4) Pub Date : 2024-02-07 Julian Herter, Frieda Stübing, Volker Lüth, Julia Zimmermann, Ann-Kathrin Lederer, Luciana Hannibal, Roman Huber, Maximilian Andreas Storz
The beneficial effects of a plant-based diet on gut microbiota diversity are well documented, however, its impact on clinical bowel health and defecation patterns are less well understood. Vegetari...
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Association between neutrophil to high-density lipoprotein cholesterol ratio and disease severity in patients with acute biliary pancreatitis Ann. Med. (IF 4.4) Pub Date : 2024-02-09 Lin Yang, Chiyi He, Wei Wang
The neutrophil to high-density lipoprotein cholesterol ratio (NHR) is independently associated with the severity of various diseases. However, its association with acute biliary pancreatitis (ABP) ...
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M2 macrophages promote subconjunctival fibrosis through YAP/TAZ signalling Ann. Med. (IF 4.4) Pub Date : 2024-02-09 Yiwei Wang, Xingchen Geng, Zhihua Guo, Dandan Chu, Ruixing Liu, Boyuan Cheng, Haohao Cui, Chengcheng Li, Jingguo Li, Zhanrong Li
To evaluate the role of M2 macrophages in subconjunctival fibrosis after silicone implantation (SI) and investigate the underlying mechanisms.A model of subconjunctival fibrosis was established by ...
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Selecting, implementing and evaluating control and placebo conditions in light therapy and light-based interventions Ann. Med. (IF 4.4) Pub Date : 2024-02-08 Manuel Spitschan
Introduction: Light profoundly influences human physiology, behaviour and cognition by affecting various functions through light-sensitive cells in the retina. Light therapy has proven effective in...
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Association between sleep duration, depression and breast cancer in the United States: a national health and nutrition examination survey analysis 2009–2018 Ann. Med. (IF 4.4) Pub Date : 2024-02-08 Yufan Cai, Yizhou Zhaoxiong, Wei Zhu, Haiyu Wang
Breast cancer is the most common cancer in women, threatening both physical and mental health. The epidemiological evidence for association between sleep duration, depression and breast cancer is i...
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MUC1-EGFR crosstalk with IL-6 by activating NF-κB and MAPK pathways to regulate the stemness and paclitaxel-resistance of lung adenocarcinoma Ann. Med. (IF 4.4) Pub Date : 2024-02-07 Hongyu Xu, Zedong Du, Zhihui Li, Xianguo Liu, Xueting Li, Xuan Zhang, Jiayu Ma
The chemotherapy resistance often leads to chemotherapy failure. This study aims to explore the molecular mechanism by which MUC1 regulates paclitaxel resistance in lung adenocarcinoma (LUAD), prov...
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Daylight quality: high-transmittance glass versus low transmittance glass - effects on daylight quality, health, comfort and energy consumption Ann. Med. (IF 4.4) Pub Date : 2024-02-05 Carlo Volf, Paul Michael Petersen, Anders Thorseth, Stefan Vestergaard, Klaus Martiny
Introduction: This study investigated the health effects of two different architectural glass types: A two-layered low-iron high transmittance glass and a three-layered low energy glass with lower ...
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Catastrophic injuries and exertional medical events in lacrosse among youth, high school and collegiate athletes: longitudinal surveillance over four decades (1982–2020) Ann. Med. (IF 4.4) Pub Date : 2024-02-09 Garrett A. Moseley, Andrew E. Lincoln, Jonathan A. Drezner, Randi DeLong, Erin Shore, Nina Walker, Johna K. Register-Mihalik, Robert C. Cantu, Kristen L. Kucera
To determine the incidence rates (IRs) of catastrophic injuries and exertional medical events in lacrosse athletes.Catastrophic injuries and exertional medical events in lacrosse in the US among yo...
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Understanding adaptive tasks in cardiac rehabilitation among patients with acute myocardial infarction: a qualitative study Ann. Med. (IF 4.4) Pub Date : 2024-02-02 Xiyi Wang, Dandan Chen, Ping Zou, Hui Zhang, Xunhan Qiu, Li Xu, Geraldine Lee
While Cardiac Rehabilitation (CR) programs have shown effectiveness in improving cardiac outcomes, there is limited understanding of how patients perceive and adapt to these interventions. Furtherm...
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The association between internet addiction and sleep quality among medical students in Saudi Arabia Ann. Med. (IF 4.4) Pub Date : 2024-01-31 Mohammad Ahmed Hammad, Mohammed Hussain Feheed Alyami, Huda Shaaban Awed
Sleep is one of the fundamental human needs, essential for maintaining a high quality of life and mental and physical well-being across all age groups. Poor sleep quality often stems from negative ...
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Body mass index and weight loss as risk factors for poor outcomes in patients with idiopathic pulmonary fibrosis: a systematic review and meta-analysis Ann. Med. (IF 4.4) Pub Date : 2024-02-01 Xing He, Jiaqi Ji, Chi Liu, Zeli Luo, Jialong Tang, Haiying Yan, Lu Guo
The association between nutritional status and prognosis of idiopathic pulmonary fibrosis (IPF) remains unclear. This systematic review and meta-analysis aimed to explore the effect of body mass in...
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Effects of intravenous rtPA in patients with minor stroke Ann. Med. (IF 4.4) Pub Date : 2024-01-30 Zhihao Lei, Shuanglin Li, Hongye Feng, Xiaohong Wu, Shiyu Hu, Jun Li, Gelin Xu, Lijie Ren, Suyue Pan
Whether minor ischemic stroke (MIS) patients can benefit from intravenous thrombolysis (IVT) remains controversial. The association between the efficacy of IVT and baseline National Institute of He...
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Parents’ lived experience of early risk assessment for cerebral palsy in their young child using a mobile application after discharge from hospital in the newborn period Ann. Med. (IF 4.4) Pub Date : 2024-02-01 Annemette Brown, Åsa B. Tornberg, Inger Kristensson Hallström
General Movement assessment (GMA) is considered the golden standard for early identification of infants with a high risk of developing cerebral palsy (CP). The aim of this study was to explore pare...
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Elevated expression of hsa_circ_0000479 in neutrophils correlates with features of systemic lupus erythematosus Ann. Med. (IF 4.4) Pub Date : 2024-02-01 Ranran Yao, Liling Xu, Gong Cheng, Ziye Wang, Ruyu Liang, Wenwen Pei, Lulu Cao, Yuan Jia, Hua Ye, Fanlei Hu, Yin Su
Accumulating evidence suggests that differentially expressed circular RNAs (circRNAs) play critical roles in immune cells of systemic lupus erythematosus (SLE) patients. Hsa_circ_0000479 has been s...
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SARS-CoV-2 vaccination in inflammatory bowel disease patients is not associated with flares: a retrospective single-centre Swiss study Ann. Med. (IF 4.4) Pub Date : 2024-01-30 Laura N. Rossier, Natalie P. Décosterd, Christoph B. Matter, Dominic A. Staudenmann, André Moser, Bernhard Egger, Frank W. Seibold
Vaccination hesitancy is an important barrier to vaccination among IBD patients. The development of adverse events is the main concern reported. The purpose of this monocentric study was to assess ...
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The efficacy and safety of enhanced recovery after surgery (ERAS) Program in laparoscopic distal gastrectomy: a systematic review and meta-analysis of randomized controlled trials Ann. Med. (IF 4.4) Pub Date : 2024-01-27 Qihui Tian, Hongying Wang, Tianyu Guo, Bing Yao, Yefu Liu, Bo Zhu
Although ERAS Program had some advantages in laparoscopic distal gastrectomy (LDG), its efficacy and safety remained unclear. We conducted a systematic review and meta-analysis to assess the effica...
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Opioids in geriatric units in 14 Belgian hospitals: prevalence, dosage and associated factors Ann. Med. (IF 4.4) Pub Date : 2024-01-31 Wim Henri Janssens, Nele J. Van Den Noortgate, Veerle Mouton, Peter Desmet, Katrien Van Puyvelde, Elke Steen, Caroline Maere, Katlijn Van Mulders, Eva De Raes, Julien Dekoninck, Celine Kympers, Bart Werbrouck, Jozefien Delaere, Ruth D. Piers
Introduction: Adverse effects of opioids are common among older individuals, and undertreatment as well as overuse can be an issue. Epidemiological data on opioid use in older individuals are avail...
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Substance basis and pharmacological mechanism of heat-clearing herbs in the treatment of ischaemic encephalopathy: a systematic review and network pharmacology Ann. Med. (IF 4.4) Pub Date : 2024-01-29 Andong Zhao, Qianqian Sun, Jiahao Zhang, Tian Hu, Xuewei Zhou, Chuan Wang, Jiping Liu, Bin Wang
Ischaemic encephalopathy is a common cerebrovascular disease caused by insufficient blood supply to the cerebral vessels. The ischaemic encephalopathy is closely associated with the development of ...
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Gamified exercise for the distal upper extremity in people with post-stroke hemiparesis: feasibility study on subjective perspectives during daily continuous training Ann. Med. (IF 4.4) Pub Date : 2024-01-31 Kazuki Ito, Shintaro Uehara, Akiko Yuasa, Kazuki Ushizawa, Shigeo Tanabe, Yohei Otaka
Dose (number of repetitions) has been suggested as a key element in the effectiveness of rehabilitation exercises to promote motor recovery of the hemiparetic upper limb. However, rehabilitation ex...
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Experiences of young adults affected by cancer within an 8-week yoga intervention delivered by videoconference: a qualitative interview study Ann. Med. (IF 4.4) Pub Date : 2024-01-30 Emma McLaughlin, Nafeel Arshad, Kelsey Ellis, Amy Chen, Kate Fougere, S. Nicole Culos-Reed, Amanda Wurz, Yoga for Young Adults Patient Advisory Board Members
Yoga may reduce negative cancer- and treatment-related effects and help improve a range of outcomes, including flexibility, mindfulness, and quality of life among adults affected by cancer. Yet the...
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Association of non-selective β blockers with the development of renal dysfunction in liver cirrhosis: a systematic review and meta-analysis Ann. Med. (IF 4.4) Pub Date : 2024-01-25 Xiangbo Xu, Fangbo Gao, Ting Wang, Zuyao Yang, Qingchun Zhao, Xingshun Qi
Non-selective β blockers (NSBBs) may negatively influence renal function through decreasing heart rate and cardiac output. This study aimed to systematically investigate their association.PubMed, E...
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Engaging the great circle: a qualitative study of the confederated tribes of grand Ronde’s mobile medication unit Ann. Med. (IF 4.4) Pub Date : 2024-01-25 Kim A. Hoffman, Chantell Graves, Kelly Rowe, Jennifer Worth, Kellie Pertl, James Laidler, P. Todd Korthuis, Dennis McCarty
The Confederated Tribes of the Grand Ronde Community of Oregon began a Mobile Medication Unit (MMU) as part of their Great Circle Recovery Opioid Treatment Program (OTP) to address elevated rates o...
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Brain-Derived neurotrophic factor and inflammatory biomarkers are unaffected by acute and chronic intermittent hypoxic-hyperoxic exposure in geriatric patients: a randomized controlled trial Ann. Med. (IF 4.4) Pub Date : 2024-01-22 Tom Behrendt, Jessica Ibanez Quisilima, Robert Bielitzki, Martin Behrens, Oleg S. Glazachev, Tanja Brigadski, Volkmar Leßmann, Lutz Schega
Animal and human studies have shown that exposure to hypoxia can increase brain-derived neurotrophic factor (BDNF) protein transcription and reduce systematic inflammatory cytokine response. Theref...
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Prevalence of high-risk human papillomavirus infection and genotype distribution among Kazakhstani women with abnormal cervical cytology Ann. Med. (IF 4.4) Pub Date : 2024-01-18 Aisha Babi, Torgyn Issa, Arnur Gusmanov, Ainur Akilzhanova, Alpamys Issanov, Nurgul Makhmetova, Aizada Marat, Yerbolat Iztleuov, Gulzhanat Aimagambetova
This study aimed to identify the prevalence and distribution of high-risk human papillomavirus (HR-HPV) types among Kazakhstani women with abnormal cervical cytology.A cross-sectional study was per...