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Addressing hepatitis delta in primary care practices in the US: a narrative review Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-15 Tatyana Kushner, Richard R. Andrews
Infection with the hepatitis delta virus (HDV), a unique RNA virus that requires hepatitis B virus (HBV) antigens for its assembly, replication, and transmission, causes severe viral hepatitis. Com...
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Evaluation of effect of brief-intensive cognitive behavior therapy on symptoms severity in relation with catastrophic cognition in patients with panic disorder: a randomized controlled trial Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-11 Rasoul Sabri Piro, Perjan Hashim Taha
Introduction: Due to a dearth of evidence, we examined the effectiveness of brief-intensive CBT on symptom severity and catastrophic cognition in patients with panic disorder (PD).Materials and Met...
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Treatment patterns and outcomes among adults with immune thrombocytopenia receiving pharmaceutical second-line therapies: a retrospective cohort study using administrative claims data Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-11 Yi Liang, Karen Rascati, Jamie C. Barner, Kenneth A. Lawson, Radhika Nair
Objectives: To describe and compare real-world treatment patterns and clinical outcomes among individuals with immune thrombocytopenia (ITP) receiving second-line therapies (rituximab, romiplostim,...
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Extemporaneous combination therapy with nebivolol/amlodipine for the treatment of hypertension: a real-world evidence study in Europe Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-03-08 Giovambattista Desideri, Riccardo Cipelli, Valeria Pegoraro, Claudio Ripellino, Marco Miroddi, Suada Meto, Mario Gori, Paolo Fabrizzi
Objective: The investigation of the real-world use of the extemporaneous combination of nebivolol and amlodipine (NA-EXC) in adult patients diagnosed with hypertension in Europe.Methods: Retrospect...
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Real-world diagnostic landscape and incidence of pulmonary hypertension in adult congenital heart disease patients using administrative claims data in Japan Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-29 Tomoko Ishizu, Yasuhiro Hayashi, Natsuko Tokushige, Junichi Omura
Background: Although pulmonary hypertension (PH) and Eisenmenger’s syndrome (ES) are common complications in adult congenital heart disease (ACHD), the frequency of diagnostic tests and the inciden...
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Real-world evidence of Pressure-Enabled Drug Delivery for trans-arterial chemoembolization and radioembolization among patients with hepatocellular carcinoma and liver metastases Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-28 Keziah Cook, Deepshekhar Gupta, Yunjuan Liu, Chris Miller-Rosales, Fangzhou Wei, Edward Tuttle, Steven C. Katz, Richard Marshak, Alexander Y. Kim
Objectives: Pressure-Enabled Drug Delivery (PEDD), a method using pressure to advance catheter-delivered drug distribution, can improve treatment for hepatocellular carcinoma (HCC) and liver metast...
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Prevalence of comorbidities with the potential to increase the risk of nonadherence to topical ocular hypotensive medication in patients with open-angle glaucoma Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-27 M. Francesca Cordeiro, Philippe Denis, Carlo Astarita, Jonathan Belsey, Marcos Rivas, Julián García-Feijoo
To evaluate the prevalence of comorbidities that may limit or prevent adherence to topical ocular hypotensive therapy in patients with open-angle glaucoma (OAG).The UK Clinical Practice Research Da...
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Antidepressant medications have evolved in terms of speed of onset of efficacy: how can we best measure antidepressant treatment response? Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-25 Jan A. Sedway, Mark G.A. Opler, Leslie Citrome
Published in Current Medical Research and Opinion (Just accepted, 2024)
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Model-based simulation of glycaemic effect and body weight loss when switching from semaglutide or dulaglutide to once weekly tirzepatide Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-26 Shweta Urva, Joshua A Levine, Karen Schneck, Cheng Cai Tang
To evaluate the efficacy endpoints of HbA1c and body weight loss after switching from the GLP-1 receptor agonists, semaglutide or dulaglutide, to treatment with the GIP/GLP-1 receptor agonist (RA) ...
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Patient characteristics, treatment patterns, healthcare resource utilization, and costs among patients diagnosed with neurofibromatosis type 1 with and without plexiform neurofibromas in Japan Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-25 Yuichi Yoshida, Keiichi Tozawa, Ryo Koto, Chikako Iwao, Yong-Jin Kim, Lu Ban, Volkan Barut
Objectives: The objectives of this study were to retrospectively investigate the patient characteristics, treatment patterns, healthcare resource utilization (HCRU), and healthcare costs related to...
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Personality dimensions and treatment adherence among glaucoma patients: the role of self-transcendence Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-25 Dina Lešin Gaćina, Darko Marčinko, Tomislav Kuzman, Ivan Škegro, Sania Vidas Pauk, Bernarda Škegro, Martina Tomić, Tomislav Bulum, Sonja Jandroković
Cloninger's psychobiosocial model of personality proposes that consistent patterns of health behavior are determined by the complex interaction of different neurobiological processes of the patient...
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Combining biomarkers of BNIP3 L, S100B, NSE and accessible measures to prediction sepsis-associated encephalopathy: a prospective observational study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-22 Nannan Zhang, Keliang Xie, Fei Yang, Yunying Wang, Xinhao Yang, Lina Zhao
Accurate identification of delirium in sepsis patients is crucial for guiding clinical diagnosis and treatment. However, there are no accurate biomarkers and indicators at present. We aimed to iden...
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Is dependent cannabis use in adult hospitalizations with inflammatory bowel disease associated with major adverse cardiovascular and cerebrovascular events? Insights from National Inpatient Sample Analysis Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-20 Vamsikalyan Borra, Nithya Borra, Gayatri Bondi, Sai Goutham R Yartha, Naga Vamsikrishna Machineni, Charu Agarwal, Karthikeya Ramasahayam, Purnachandra Rao Kuchipudi, Sravya R Mundla, Prerna Bansal, Sagar A Bathija, Ikechukwu R Ogbu, Rupak Desai
Inflammatory bowel disease (IBD) and dependent cannabis use or cannabis use disorder (CUD+) are independent risk factors for cardiovascular diseases. Usage of cannabis for pain increased in IBD pat...
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Measuring the impact of scientific publications and publication extenders: examples of novel approaches Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-20 Avishek Pal, Wesley Portegies, Jennifer Schwinn, Michael Taylor, Tomas J Rees, Sarah Thomas, Kim Brown, Gareth Morrell, Josh Nicholson, Brian Falcone, Renu Juneja
Different stakeholders, such as authors, research institutions, and healthcare professionals (HCPs) may determine the impact of peer-reviewed publications in different ways. Commonly-used measures ...
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Association of echocardiography-related parameters with the prognosis of liver cirrhosis: a retrospective cohort study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-19 Weiwei Wang, Liyan Dong, Yue Gao, Fangbo Gao, Zhongchao Wang, Min Ding, Chunru Gu, Zhe Li, Yue Yin, Menghua Zhu, Hongxin Chen, Hongyu Li, Xingshun Qi
Background: Cardiac morphology and function, which are conventionally evaluated by echocardiography, are often abnormal in decompensated cirrhosis. We aimed to evaluate the association of echocardi...
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Goal setting and goal attainment in patients with major depressive disorder: a narrative review on shared decision making in clinical practice Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-19 David S. Baldwin, Michael Adair, Arun Micheelsen, Daniel Oudin Åstrøm, Elin H. Reines
Narrative review of the processes of goal setting and goal attainment scaling, as practical approaches to operationalizing and implementing the principles of shared decision making (SDM) in the rou...
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Understanding the impact of non-alcoholic steatohepatitis with metabolic comorbidities on adults: a real-world qualitative study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-16 Shraddha Shinde, Natalie Taylor, Chanadda Chinthammit, Rozanne Wilson, Somali Misra Burgess, Jiat-Ling Poon
Objective: Limited real-world evidence exists to better understand the patient experience of living with symptoms and impacts of non-alcoholic steatohepatitis (NASH). This study aimed to (1) descri...
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Good Publication Practice (GPP) Guidelines for company-sponsored biomedical research from the point of view of the diverse authors involved in its publication Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-16 Leslie Citrome, Lisa M DeTora, Dikran Toroser, Angela Sykes, Trevor Lane, Eline Hanekamp, Laura Dormer, Faith DiBiasi, Lise Baltzer
Published in Current Medical Research and Opinion (Just accepted, 2024)
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Role of the brain-sparing effect on retinopathy of prematurity in newborns with fetal growth restriction Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-16 Osman Ahmet Polat, Mehmet Mete Kirlangic, Erdem Sahin, Yusuf Madendag, Cem Evereklioglu, Fatih Horozoglu, Cagatay Karaca
This study aimed to investigate the role of the brain-sparing effect (BSE) on retinopathy of prematurity (ROP) in fetal growth restriction (FGR).In this retrospective study, 127 pregnant women were...
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Publishing clinical trial results in plain language: a clash of ethical principles? Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-14 Avishek Pal, Ingrid Klingmann, Tenzin Wangmo, Bernice Elger
Plain language resources (PLR) are lay summaries of clinical trial results or plain language summaries of publications, in digital/visual/language formats. They aim to provide accurate information ...
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CercaTest Red, a novel urine-based point-of-care test for the detection of preeclampsia Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-14 Xuemin Liu, Jun Xu, Chao Liu, Xingmin Li
Preeclampsia (PE) poses a serious threat to the health of the pregnant woman and her developing fetus due to the difficulty in diagnosing the condition. The disease can develop and worsen suddenly ...
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Humanistic burden of mucopolysaccharidoses: a systematic literature review Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-08 Joyce W. Li, Kevin Yan, Chakrapani Balijepalli, Eric Druyts
To systematically review the literature and summarize the health related of quality of life (HRQoL) of patients undergoing treatment for mucopolysaccharidoses (MPS), a rare, hereditary lysosomal st...
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Effectiveness and safety of anticoagulants among patients with venous thromboembolism and active cancer who also had prior bleed or prior renal disease Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-13 Alexander T. Cohen, Virginia Noxon, Amol D. Dhamane, Shrushti Shah, Dionne M. Hines, Tamuno Alfred, José Chaves, Xuemei Luo
Patients with active cancer and venous thromboembolism (VTE) have elevated risk of recurrent VTE (rVTE) and major bleeding (MB). The risk is even higher within those with a prior bleeding event or ...
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Audit of adherence to international guidelines (IDSA) in the treatment of infectious meningitis in pediatric patients in Jordan Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-13 Dina Mohialdin, Rana Abu-Farha, Rama ALkhawaldeh, Mohammed Zawiah, Khawla Abu Hammour
This study aims to audit the adherence of Jordanian medical care staff to the guidelines provided by the Infectious Disease Society of America (IDSA) for managing pediatric patients admitted with s...
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The role of lactate-to-albumin ratio to predict 30-day risk of death in patients with sepsis in the emergency department: a decision tree analysis Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-12 Gianni Turcato, Arian Zaboli, Serena Sibilio, Marta Parodi, Michael Mian, Francesco Brigo
Accurately estimating the prognosis of septic patients on arrival in the emergency department (ED) is clinically challenging. The lactate-to-albumin ratio (LAR) has recently been proposed to improv...
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Successful treatment of severe alcohol withdrawal delirium with very high-dose diazepam (260–480 mg) administration Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-12 Şükrü Alperen Korkmaz, Ebru Aldemir, Demet Güleç Öyekçin
Alcohol withdrawal delirium, commonly known as “delirium tremens (DT)”, is the most severe clinical condition of alcohol withdrawal syndrome (AWS). Symptoms of DT include changes in consciousness a...
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Factors and economic burden of non-severe hypoglycemia among insulin-treated type 2 diabetes patients: a cross-sectional study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-12 Natapong Kosachunhanun, Danil Wongsa, Unchalee Permsuwan
This cross-sectional survey was performed to assess the prevalence, factors, and economic burden of non-severe hypoglycemia among insulin-treated type 2 diabetes (T2D) patients in northern Thailand...
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Association between pan-ımmune ınflammatory value and ulcerative colitis Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-11 Aslıhan Mete Yıldırım, Oğuzhan Yıldırım
Ulcerative colitis is a chronic idiopathic disease that causes inflammation of the colon and rectum, progressing with relapses and remissions. Systemic inflammatory index (SII) and pan-immune infla...
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Treatment patterns of galcanezumab versus standard of care preventive migraine medications over 24 months: a US retrospective claims study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-09 Oralee J. Varnado, Michelle Vu, Erin Buysman, Gilwan Kim, Gayle Allenback, Margaret Hoyt, Helen Trenz, Feng Cao, Lars Viktrup
To describe long-term (24-month) treatment patterns of patients initiating galcanezumab versus standard-of-care (SOC) preventive migraine treatments including anticonvulsants, beta-blockers, antide...
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Short-term COVID-19 vaccine adverse effects among adults in Ekiti State, Nigeria Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-07 Bolade Folasade Dele-Ojo, Adedapo Adesokan, Joseph Olusesan Fadare, Paul Oladapo Ajayi, Taiwo Hussean Raimi, Samuel Ayokunle Dada, Ojo Owolabi Dele, James Ayodele Ogunmodede, Tope Michael Ipinimo, Olumuyiwa Elijah Ariyo, Brian Godman
The safety of the COVID-19 vaccines has been a topic of concern globally. This issue of safety is associated with vaccine hesitancy due to concerns about the adverse effects of the vaccines. Conseq...
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Risk prediction models of mortality after hip fracture surgery in older individuals: a systematic review Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-07 Ying Sun, Yanhui Liu, Yaning Zhu, Ruzhen Luo, Yiwei Luo, Shanshan Wang, Zihang Feng
This study aimed to critically assess existing risk prediction models for postoperative mortality in older individuals with hip fractures, with the objective of offering substantive insights for th...
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Preferences for different treatment options among people living with acromegaly in the US Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-05 Jill Sisco, Mattias Furumalm, Cecilie Yssing, Anna Okkels, Stojan Zavisic
Objective: Acromegaly is a rare hormonal disorder that results in enlargement of the face, hands and feet. It is associated with comorbidities, increased mortality, reduced quality of life and econ...
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Between human and AI: assessing the reliability of AI text detection tools Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-02-02 Valentina Bellini, Federico Semeraro, Jonathan Montomoli, Marco Cascella, Elena Bignami
Large language models (LLMs) such as ChatGPT-4 have raised critical questions regarding their distinguishability from human-generated content. In this research, we evaluated the effectiveness of on...
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Patient journey of civilian adults diagnosed with posttraumatic stress disorder—A chart review study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-30 Lori L. Davis, Annette Urganus, Patrick Gagnon-Sanschagrin, Jessica Maitland, Jerome Bedard, Remi Bellefleur, Martin Cloutier, Annie Guérin, Jyoti Aggarwal
To assess the journey of individuals from experiencing a traumatic event through onset of symptoms, diagnosis, and treatment of posttraumatic stress disorder (PTSD).Patient- and psychiatrist-level ...
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Biofilm-producing antibiotic-resistant bacteria in Indian patients: a comprehensive review Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-27 Susmita Datta, Soma Nag, Dijendra Nath Roy
For the past few years, microbial biofilms have been emerging as a significant threat to the modern healthcare system, and their prevalence and antibiotic resistance threat gradually increase daily...
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The power of language: how to bridge the gap between healthcare research and patients – a scoping review Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Sally-Anne Dews, Rachel Daley, Akhil Bansal, Jennifer Preston, Natalie Bohm
The value of patient involvement to the design, conduct, and outcomes of healthcare research is increasingly being recognized. Patient involvement also provides greater patient accessibility and co...
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Analgesic onset and efficacy of a fast-acting formulation of acetaminophen in a postoperative dental impaction pain model Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Andrew Myers, Cathy Gelotte, Annette Zuckerman, Brenda Zimmerman, Ami Shenoy, Dan Qi, Stephen A. Cooper
Speed of onset can be critical to an analgesic’s efficacy treating acute pain. To enhance onset, a new oral acetaminophen formulation intended to be fast acting was developed. Two studies evaluated...
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Diabetes management, dietary supplements use and the effect of coronavirus pandemic on diabetes patients in Serbia: a cross-sectional study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Milana Vuković, Jelena Jovičić Bata, Nemanja Todorović, Gorana Puača, Dunja Vesković, Jelena Čanji Panić, Tihomir Dugandžija, Mladena Lalić-Popović
Diabetes mellitus (DM) is a significant public health challenge in Serbia, mirroring the situation in other European middle-income countries. The aims of this study were to examine the disease-rela...
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What to expect in 2024: important health economics and outcomes research (HEOR) trends Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Ivo Abraham, Mickael Hiligsmann, Kenneth K. C. Lee, Leslie Citrome, Giorgio L. Colombo, Mike Gregg
Published in Current Medical Research and Opinion (Vol. 40, No. 2, 2024)
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Associations of serum uric acid levels and anthropometric parameters with non-alcoholic fatty liver disease in healthy individuals: innovative insights from a cross-sectional study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Ahmet Aydin, Sabin Goktas Aydin
Non-alcoholic fatty liver disease (NAFLD is a spectrum of liver disease with a rising prevalence, ranging from simple steatosis to steatohepatitis and cirrhosis, where a significant minority face p...
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The impact of psychedelics on patients with alcohol use disorder: a systematic review with meta-analysis Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Dakota Sicignano, Adrian V. Hernandez, Benjamin Schiff, Nawal Elmahy, C. Michael White
Critique the available systematic review and de novo assessment of the role of psychedelics in the treatment of alcohol use disorder.A systematic literature search of PubMed was completed from 1960...
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Kalium phosphoricum comp. in patients with neurasthenia: a randomized, double-blind, placebo-controlled clinical trial Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Juliane Hellhammer, Luitgard Spitznagel-Schminke, Rebecca Hufnagel
This Phase IV placebo-controlled clinical trial was designed to demonstrate the efficacy and safety of the product Neurodoron (Kalium phosporicum comp., KPC) in patients with neurasthenia.This mono...
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The use of large language models in medicine: proceeding with caution Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Jiawen Deng, Areeba Zubair, Ye-Jean Park, Eesha Affan, Qi Kang Zuo
Large language models, like ChatGPT and Bard, have potential clinical applications due to their ability to generate conversational responses and encode medical knowledge. However, their clinical ad...
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A confirmatory factor analysis of an electronic format painDETECT questionnaire for patients with low back pain Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Samuel Lapkin, Stone Sima, Zachary Gan, Ashish D. Diwan
The substantial burden of low back pain on patients and healthcare systems is exacerbated by unclear pathology and ineffective diagnostic methods, hindering effective management. The painDETECT que...
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The relationship between polypharmacy and physical performance in patients with early-stage Alzheimer’s disease Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Aysegul Akkan Suzan, Banu Ozen Barut
Our aim was to evaluate the association between polypharmacy and certain physical performance measures used to assess ambulation in early-stage Alzheimer patients.This cross-sectional study was con...
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A matching-adjusted indirect comparison of the efficacy of elranatamab versus physician’s choice of treatment in patients with triple-class exposed/refractory multiple myeloma Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Isha Mol, Yannan Hu, Thomas W. LeBlanc, Joseph C. Cappelleri, Haitao Chu, Guido Nador, Didem Aydin, Alex Schepart, Patrick Hlavacek
For patients with triple-class exposed/refractory multiple myeloma (TCE/R MM), prognosis is poor and effective treatment options are limited. Elranatamab is a novel B-cell maturation antigen (BCMA)...
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Health-related quality of life in pre-pubertal children with pediatric growth hormone deficiency: 12-month results from a phase 3 clinical trial of once-weekly somatrogon versus once-daily somatropin Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Jane Loftus, Julia Quitmann, Srinivas Rao Valluri
Treatment of pediatric growth hormone deficiency (pGHD) with daily injection of recombinant human growth hormone (somatropin) aims to increase height velocity and improve health-related quality of ...
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The association between influenza vaccine effectiveness and egg-based manufacturing technology: literature review and US expert consensus Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Archana Chatterjee, Karita Ambrose, David H. Canaday, Shirley Delair, Ngozi Ezike, Victor C. Huber, Ravi Jhaveri, Ann-Christine Nyquist, Abigail Sporer, Meera Varman, Renuga Vivekanandan, Radek Wojcik, Ravi Jandhyala
Influenza is associated with significant disease burden in the US and is currently best controlled by vaccination programs. Influenza vaccine effectiveness (VE) is low and may be reduced by several...
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Effectiveness of bDMARDs in ankylosing spondylitis patients by biologic use: experience from the CorEvitas PsA/SpA Registry Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Philip J. Mease, Taylor Blachley, William N. Malatestinic, Leslie R. Harrold, Blessing Dube, Jeffrey R. Lisse, Rebecca J. Bolce, Theresa M. Hunter
To describe bDMARD initiators by biologic experience among ankylosing spondylitis (AS) patients and change in disease activity and patient-reported outcomes (PROs) in real-world US patients.We incl...
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The effects of COVID-19 infection on working memory: a systematic review Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Rui Cui, BeiYao Gao, RuiDong Ge, MingZhen Li, Min Li, Xi Lu, Shan Jiang
Studies demonstrate that people who have been infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, have experienced cognitive dysfunction, incl...
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Primary Budd-Chiari syndrome versus sinusoidal obstruction syndrome: a review Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Feifei Lu, Siqi Jia, Huiyuan Lu, Haonan Zhao, Zhe Li, Yuzheng Zhuge, Fernando Gomes Romeiro, Nahum Mendez-Sanchez, Xingshun Qi
Budd-Chiari syndrome (BCS) and sinusoidal obstruction syndrome (SOS) are two major vascular disorders of the liver, of which both can cause portal hypertension related complications, but their loca...
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Efficacy of tyrosine-kinase-2 and phosphodiesterase-4 inhibitors for scalp psoriasis: a systematic review and meta-analysis Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Sotirios G. Tsiogkas, Eleni K. Karamitrou, Maria G. Grammatikopoulou, Efterpi Zafiriou, Dimitrios P. Bogdanos
Psoriasis of the scalp is challenging to manage. The only approved oral tyrosine kinase 2 and phosphodiesterase 4 inhibitors for psoriasis are deucravacitinib and apremilast. The aim of this study ...
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Effect of preoperative moderate-dose statin and duration on acute kidney injury after cardiac surgery: a retrospective cohort study Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Jicheng Jiang, Xinyun Liu, Zhaoyun Cheng, Qianjin Liu, Wenlu Xing
The impact of preoperative statin use on postoperative acute kidney injury (AKI) is uncertain. We aimed to examine the association of statin therapy before cardiac surgery with postoperative AKI.Th...
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Long-term economic outcomes of ureteral injury in the United States Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-24 Steven D. McCarus, Emily F. Shortridge, Tomomi Kimura, Qi Feng, Wei Han, Baoguo Jiang
Ureteral injuries (UIs) during surgical procedures can have serious consequences for patients. Although UIs can result in substantial clinical burden, few studies report the impact of these injurie...
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A machine learning-based algorithm to identify U-500R insulin candidates among adults with type 2 diabetes mellitus in US retrospective databases Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-23 Raja H. Patel, Ludi Fan, Neal R. Kelly, Felicia Gelsey, Jeffrey K. Hertzberg, Alan James Michael Brnabic
To develop a machine learning-based predictive algorithm to identify patients with type 2 diabetes mellitus (T2DM) who are candidates for initiation of U-500R insulin (U-500R).A retrospective cohor...
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Is nociplastic pain, a new pain category, associated with biochemical, hematological, and inflammatory parameters? Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-22 Hilal Telli, Çağla Özdemir
The aim of the study was to evaluate the relationship between biochemical, hematological, and inflammatory parameters and pain in patients with nociplastic pain.In this cross-sectional study, a tot...
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Colorectal cancer screening uptake and adherence by modality at a large tertiary care center in the United States: a retrospective analysis Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-22 Catherine Cheney, Alice Parish, Donna Niedzwiecki, Chukwuemeka Oko, Christy Walters, David Halpern, Leah Helmueller, Nancy El Hoyek, Lesley-Ann Miller-Wilson, Brian A. Sullivan
Real-world data is crucial to inform existing opportunistic colorectal cancer (CRC) prevention programs. This study aimed to assess CRC screening adherence and utilization of various screening moda...
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Clinical outcomes and medical resource utilization of toripalimab combination therapy versus bevacizumab plus chemotherapy in advanced non-squamous non-small cell lung cancer Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-22 Huijie Qi, Wenxin Zhang, Bicui Chen, Qiong Zhan, Tianxiao Wang, Huanying Shi, Yanchen Liu, Yan Wang, Mingkang Zhong, Xiaojin Shi, Fangfang Shen, Qunyi Li
This study aimed to evaluate the real-world clinical efficacy and safety, economic burdens and medical resource utilization (MRU) of toripalimab treatment patterns compared with bevacizumab plus ch...
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The two different profiles in heart failure with preserved ejection fraction and type 2 diabetes mellitus: ischemic and diabetic Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-19 José Carlos Arévalo Lorido, Juana Carretero Gómez, Alicia Conde Martel, Oscar Aramburu Bodas, Joan Carles Trullás, Francisco Javier Carrasco Sánchez, Luis Manzano Espinosa, Jose Manuel Cerqueiro González, Carmen Moreno García, Jesús Casado Cerrada, Manuel Montero Pérez-Barquero
Two profiles of patients with heart failure with preserved ejection fraction (HFpEF) and type 2 diabetes mellitus (T2DM) can be discerned: those with ischemic and those with diabetic cardiomyopathy...
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Association between COVID-19 vaccines and development of chronic morbidities: a cross-sectional study in the Jordanian population Curr. Med. Res. Opin. (IF 2.3) Pub Date : 2024-01-16 Mai I. AL-Hawamdeh, Rana Abu-Huwaij, Thabit A. Astiti, Ahmed K. Al-Debe’e, Omar J. Abazeed, Mohammed A. Raees
In Jordan, individuals recently diagnosed with chronic illnesses have expressed concerns with regard to COVID-19 vaccines. This study aims to investigate potential associations between COVID-19 vac...