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Knowledge and Awareness of Osteoporosis: A Survey of Physical Therapy Providers in Saudi Arabia Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-3-18 Muataz Almaddah, Fahad Alzahrani, RiziqAllah Gaowgzeh, Abdullah Alqarni, Rani Othman, Afnan Gmmash
Background. Osteoporosis “OP” is classified as one of the most serious health conditions worldwide. OP increases the skeletal fracture risk by 35%, particularly at hip, spine, and wrist joints. Healthcare professionals should be aware of OP clinical signs and have good knowledge while managing all patients. Objectives. This study aims to investigate the current level of osteoporosis knowledge and awareness
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Efficacy and Safety of Pericapsular Nerve Group Block for Hip Fracture Surgery under Spinal Anesthesia: A Meta-Analysis Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-3-13 Shukai Li, Jing An, Chengyu Qian, Zhixue Wang
Objective. To evaluate the effectiveness and safety of pericapsular nerve group (PENG) block for hip fracture surgery under spinal anesthesia. Methods. This meta-analysis was registered on INPLASY (INPLASY202270005). PubMed, Embase, Cochrane, CNKI, and Wanfang databases were searched to collect the randomized controlled trials of the PENG block applied to hip fracture surgery in the setting of spinal
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Blood Features Associated with Viral Infection Severity: An Experience from COVID-19-Pandemic Patients Hospitalized in the Center of Iran, Yazd Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-3-12 Fatemeh Sadeghi-Nodoushan, Mohamad Reza Zare-Khormizi, Seyedhossein Hekmatimoghaddam, Fatemeh Pourrajab
Pandemics such as coronavirus disease 2019 (COVID-19) can manifest as systemic infections that affect multiple organs and show laboratory manifestations. We aimed to analyze laboratory findings to understand possible mechanisms of organ dysfunction and risk stratification of hospitalized patients in these epidemics. Methods. This retrospective study was conducted among patients admitted to COVID-19
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The Role of Pharmaceutical Innovation in Clinical Practice Guidelines for Chronic Diseases Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-3-12 Meaghan Roach, Natalie Land, Jennifer Hernandez, Reina Rau, Jacquelyn W. Chou, Stacey S. Hickson, Danielle F. Rollmann, J. Ross Maclean
Background. Over the last 25 years, clinical practice guidelines have emerged as a means to standardize and improve care. As pharmaceutical innovations develop, guidelines are updated to incorporate new interventions. However, the extent to which pharmacotherapies are represented as treatment options in guideline recommendations has not been well elucidated. This study aimed to quantify the role pharmacotherapy
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Genetically Engineered Microorganisms and Their Impact on Human Health Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-3-9 Marzie Mahdizade Ari, Leila Dadgar, Zahra Elahi, Roya Ghanavati, Behrouz Taheri
The emergence of antibiotic-resistant strains, the decreased effectiveness of conventional therapies, and the side effects have led researchers to seek a safer, more cost-effective, patient-friendly, and effective method that does not develop antibiotic resistance. With progress in synthetic biology and genetic engineering, genetically engineered microorganisms effective in treatment, prophylaxis,
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Tumour Recurrence, Depth of Invasion, and Temple Location as Independent Prognostic Parameters of Lymph Node Metastases of Head and Neck Cutaneous Squamous Cell Carcinomas Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-3-8 Zuzana Horakova, Ivo Starek, Jana Zapletalova, Richard Salzman
The excellent survival rate of cutaneous squamous cell carcinoma (cSCC) exceeding 90% is reduced by the presence of nodal metastases by over 50%. We analysed various risk parameters of cSCC to predict the incidence of nodal metastases. A total of 118 patients with the head cSCC were included in a single-institution retrospective study covering the period from 2008 to 2020. Tumour recurrence, temple
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Pharmacokinetics, Safety, and Tolerability of Tenapanor in Healthy Chinese and Caucasian Volunteers: A Randomized, Open-Label, Single-Center, Placebo-Controlled Phase 1 Study Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-3-6 Gang Yuan, Yili Chen, Li Li, Xin Wang, Gang Wei, Jiawei Zeng, Ai-Min Hui, Yueyun Jiang, Han Zhao, Lei Diao, Yongchun Zhou, Yinglian Xiao, Minhu Chen
Background. Tenapanor is a locally acting selective sodium-hydrogen exchanger 3 inhibitor with the potential to treat sodium/phosphorus and fluid overload in various cardiac-renal diseases, which has been approved for constipation-predominant irritable bowel syndrome in the US. The pharmacokinetics (PK) of tenapanor and its metabolite tenapanor-M1 (AZ13792925), as well as the safety and tolerability
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The Effect of a Combination of Vibration and External Cold on Pain Caused during Vaccine Injection in Infants: A Randomized Clinical Trial Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-3-4 Zahra Unesi, Zahra Amouzeshi, Javad Jamavar, Fatemeh Mahmoudzadeh Zarandi
Aim. This study was conducted to determine the effect of combining vibration and external cold on pain caused by vaccine injection among six-month-old infants. Design. Randomized controlled trial. Methods. In this clinical trial, 80 eligible infants were selected from the infants referred to a health center as per the inclusion criteria. The infants were assigned to either a control group or an intervention
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A Nomogram to Predict Benign/Malignant Mediastinal Lymph Nodes Based on EBUS Sonographic Features Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-2-29 Bingchao Ling, Weishun Xie, Yi Zhong, Taowen Feng, Yueli Huang, Lianying Ge, Aiqun Liu
Background. Endobronchial ultrasound (EBUS) sonographic features help identify benign/malignant lymph nodes while conducting transbronchial needle aspiration (TBNA). This study aims to identify risk factors for malignancy based on EBUS sonographic features and to estimate the risk of malignancy in lymph nodes by constructing a nomogram. Methods. 1082 lymph nodes from 625 patients were randomly enrolled
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Cocktail of Ropivacaine, Morphine, and Diprospan Reduces Pain and Prolongs Analgesic Effects after Total Knee Arthroplasty: A Prospective Randomized Controlled Trial Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-2-28 Zhenyu Luo, Weinan Zeng, Xi Chen, Qiang Xiao, Anjing Chen, Jiali Chen, Haoyang Wang, Zongke Zhou
Background. Local infiltration analgesia (LIA) provides postoperative analgesia for total knee arthroplasty (TKA). The purpose of this study was to evaluate the analgesic effect of a cocktail of ropivacaine, morphine, and Diprospan for TKA. Methods. A total of 100 patients from September 2018 to February 2019 were randomized into 2 groups. Group A (control group, 50 patients) received LIA of ropivacaine
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Unveiling the Influence of the Curve of Spee on Bite Force and Chewing Ability: A Comparative Study Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-2-21 Zainab Ali Alkhalaf, Mohammed Ghazi Sghaireen, Kiran Kumar Ganji, Mohammad Khursheed Alam, Rakhi Issrani, Raghad Mohammed Alsaleh, Sultana Zamil Almegren, Mahmoud Gamal Salloum
Aim. To investigate the impact of the curve of Spee (CS) accentuation on bite force, chewing ability, and additionally, other factors that influence chewing ability and bite force such as restorations, caries, gender, habits, and TMJ problems. Materials and Methods. 231 participants (118 male and 113 female, mean age = ±27.96 years) were recruited for this cross-section study. Participants completed
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Takotsubo Cardiomyopathy and Autoimmune Disorders: A Systematic Scoping Review of Published Cases Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-2-20 Mohsen Farjoud Kouhanjani, Seyed Ali Hosseini, Seyedeh Maryam Mousavi, Zahra Noroozi, Paniz Sadeghi, Armita Jokar-Derisi, Mohammad Saleh Jamshidi Mouselou, Meysam Ahmadi, Armin Attar
Introduction. Takotsubo cardiomyopathy (TCM) features transient left ventricular apical dysfunction or ballooning. The underlying mechanism remains elusive; however, evidence suggests the role of different physical and psychological stressors. We systematically reviewed patients presenting with TCM and autoimmunity to explore the link between the two conditions. Methods. We applied the Preferred Reporting
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Parotid Gland Metastases of Cutaneous Squamous Cell Carcinoma of the Head: Occult Metastases Occurrence and Their Late Manifestation Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-2-19 Zuzana Horakova, Ivo Starek, Jana Zapletalova, Richard Salzman
Cutaneous squamous cell carcinomas (cSCC) are malignant tumours with excellent prognosis unless nodal metastases develop. The aim of our study is to determine the prognostic significance of the clinical stage of parotid gland metastases and the incidence of occult cervical lymph node involvement in cSCC of the head. Our retrospective analysis includes 39 patients with cSCC parotid gland metastases
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Percutaneous Coronary Intervention with Procedural Unfractionated Heparin without Activated Clotting Time Guidance: A Unique Opportunity to Assess Thrombotic and Bleeding Events Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-2-15 Ali Z. Zgheib, Jennifer Jdaidani, Elie Akl, Suzan Khalil, Omar Chaabo, Nicolo Piazza, Fadi J. Sawaya, Abdallah G. Rebeiz
Background. Rates of major bleeding and intraprocedural thrombotic events (IPTE) in the setting of percutaneous coronary intervention (PCI) using weight-adjusted unfractionated heparin (UFH) without activated clotting time (ACT) monitoring are not known. Methods. We reviewed 2,748 consecutive patients who underwent coronary angiography at our tertiary care university hospital between January 2017 and
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A Psychometric Study of the Student Evidence-Based Practice Scale S-EBPQ-Arabic Version for Use among Undergraduate Nursing Students Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-2-13 Basmah F. Alharbi
Background. Previous studies have demonstrated the significance of evidence-based practice in improving patient care and outcomes. Therefore, integrating evidence-based practice into the health professions’ education curriculum has become a pedagogical priority. However, there is a lack of reliable and valid scales to measure students’ evidence-based practice usage, attitudes, knowledge, and skills
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Comparison of Efficacy and Safety of First-Line Treatment Options for Unresectable Stage III Non-Small Cell Lung Cancer: A Retrospective Analysis Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-2-12 Luqing Zhao, Zhiting Zhao, Xiaoqi Yan, Fei Wu, Ning Sun, Renhong Guo, Shaorong Yu, Xiao Hu, Jifeng Feng
Background. Based on PACIFIC trial, durvalumab as consolidation therapy following concurrent chemoradiotherapy (cCRT) has been a new standard treatment for unresectable stage III non-small cell lung cancer (NSCLC). In clinical applications, there are heterogeneous adjustments or novel strategies following specialized discussions in experienced multidisciplinary teams. This study retrospectively compared
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Network Pharmacology Analysis of the Therapeutic Potential of Colchicine in Acute Lung Injury Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-2-6 Fei Sun, Lijuan Zhang, Lulu Shen, Chunman Wang
Background. This study employed integrated network pharmacology approach to explore the mechanisms underlying the protective effect of colchicine against acute lung injury (ALI). Methods. We analyzed the expression profiles from 13 patients with sepsis-related ALI and 21 controls to identify differentially expressed genes and key modules. ALI-related genes were curated using databases such as DisGeNET
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Effects of Different Inspiratory Muscle Training Protocols on Exercise Capacity, Respiratory Muscle Strength, and Health-Related Quality of Life in Patients with Hypertension Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-2-3 İrem Hüzmeli, Nihan Katayıfçı, Fatih Yalçın, Esra Doğru Hüzmeli
Aim. This study aimed to explore how varying inspiratory muscle training workloads affect exercise capacity, health-related quality of life (HrQoL), depression, peripheral and respiratory muscle strength, pulmonary function, dyspnea, fatigue, and physical activity levels in hypertension (HT) patients. Methods. A randomized, controlled three-arm study. Forty-five patients (58.37 ± 8.53 y, 7F/38M) with
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Community Pharmacists’ Knowledge and Perception towards Telepharmacy Services and Willingness to Practice It in Light of COVID-19 Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-1-31 Ayesha Siddiqua, Soha Makki, Sazada Siddiqui, Randa A. Abdelkarim, Tahani Jubran, Wejdan Nwar, Ahlam Alqahtani, Maryam Alshehri, Maram Saeed, Arwa Khaled
Background. During the COVID-19 pandemic, there was increased adoption of telepharmacy, which has proven benefits. This study was conducted to assess the knowledge and perception of the community pharmacists of Aseer region, Saudi Arabia, towards telepharmacy services and evaluate their willingness to adopt telepharmacy in clinical practice during the COVID-19 pandemic. Materials and Methods. A cross-sectional
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GPX3-Mediated Oxidative Stress Affects Pyrimidine Metabolism Levels in Stomach Adenocarcinoma via the AMPK/mTOR Pathway Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-1-30 Yaowen Zhang, Yixin Yang, Shanshan Kuang, Yang Zhang, Hancheng Qin, Jisheng Xie
Background. Amino acid metabolism, including ATP production, nucleotide synthesis, and redox homeostatic processes, are associated with proliferation and differentiation of tumor cells. This study aimed to identify novel prognostic biomarkers and potential therapeutic targets of amino acid metabolism-related genes for stomach adenocarcinoma (STAD). Methods. RNA sequencing transcriptome data in the
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Machine Learning-Based Integrated Analysis of PANoptosis Patterns in Acute Myeloid Leukemia Reveals a Signature Predicting Survival and Immunotherapy Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-1-30 Lanlan Tang, Wei Zhang, Yang Zhang, Wenjun Deng, Mingyi Zhao
Objective. We conducted a meticulous bioinformatics analysis leveraging expression data of 226 PANRGs obtained from previous studies, as well as clinical data from AML patients derived from the HOVON database. Methods. Through meticulous data analysis and manipulation, we were able to categorize AML cases into two distinct PANRG clusters and subsequently identify differentially expressed genes (PRDEGs)
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Mediterranean-Oriented Dietary Intervention Is Effective to Reduce Liver Steatosis in Patients with Nonalcoholic Fatty Liver Disease: Results from an Italian Clinical Trial Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-1-25 Barbara Zanini, Federica Benini, Monica Marullo, Anna Simonetto, Angelo Rossi, Paola Cavagnoli, Alessia Bonalumi, Silvia Marconi, Marie Graciella Pigozzi, Gianni Gilioli, Alessandra Valerio, Francesco Donato, Maurizio Castellano, Chiara Ricci
Background of the Study. Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in western countries. Lifestyle interventions are recommended as the primary therapy for NAFLD. Methodology. In this clinical trial, NAFLD patients were enrolled in a 12-month dietary intervention aimed to improve their eating habits according to the Mediterranean pattern, with scheduled appointments
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Clinical Characteristics and Nomogram for Predicting Mortality in Patients with Postoperative Bloodstream Infection in Surgical Intensive Care Unit Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-1-12 Zengli Xiao, Yao Sun, Huiying Zhao, Youzhong An
Background. Bloodstream infection is amongst the leading causes of mortality for critical postoperative patients. However, data, especially from developing countries, are scary. Clinical decision-making tools for predicting postoperative bloodstream infection-related mortality are important but still lacking. Objective. To analyze the distribution of pathogens and develop a nomogram for predicting
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Evaluation of the Effect of Cichorium intybus L. on the Liver Enzymes in Burn Patients: A Randomized Double-Blind Clinical Trial Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-1-11 Abdolkhalegh Keshavarzi, Rahimeh Akrami, Mohammad M. Zarshenas, Saeid Zareie, Tayyeb Ghadimi, Ali Najafi, Mahsa Rostami Chijan, Azizallah Dehghan, Elham Zarenezhad
Burn injuries are considered an important public health problem in the world. Burns are considered the fourth most common kind of trauma in the world, after traffic accidents, falls, and interpersonal violence. Various biochemical agents are involved in the burn healing process such as cytokines (such as IL-6 and TNF-α), antioxidants, and liver and kidney damage biomarkers. Cichorium intybus L. and
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Lung Ultrasound and Bioelectrical Impedance Analysis for Fluid Status Assessing Patients Undergoing Maintenance Hemodialysis Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-1-9 Danna Zheng, Yueming Liu, Yuting Li, Juan Jin, Qiang He, Xiaogang Shen
Background. Volume overload is a fatal complication for people undergoing hemodialysis. Therefore, regulating a patient’s “dry weight” based on their fluid status is imperative. Clinical experiences are too subjective to accurately judge a patient’s fluid status, but techniques have emerged for improved fluid control in the two decades. Specifically, lung ultrasonography (LUS) uses a unique aspect
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Effects of Acupuncture-Point Stimulation on Perioperative Sleep Disorders: A Systematic Review with Meta-Analysis and Trial Sequential Analysis Int. J. Clin. Pract. (IF 2.6) Pub Date : 2024-1-4 Ying Liu, Yi Li, Meinv Liu, Meng Zhang, Jing Wang, Jianli Li
Background. Perioperative sleep disorders exert a severe adverse impact on postoperative recovery. Recently, some observational studies reported that acupuncture-point stimulation (APS) provided benefits for promoting perioperative sleep quality. However, the effects of APS on perioperative sleep disorders following general anesthesia have not been thoroughly assessed by any systematic study and meta-analysis
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The Effect of Diabetes Management Shared Care Clinic on Glycated Hemoglobin A1c Compliance and Self-Management Abilities in Patients with Type 2 Diabetes Mellitus Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-12-31 Tian Jiang, Chao Liu, Ping Jiang, Wenjun Cheng, Xiaohong Sun, Jing Yuan, Qiaoling Wang, Yanlei Wang, Shihui Hong, Haiyan Shen, Dongchun Zhu, Yi Zhang, Fang Dai, Jing Hang, Jiguo Li, Honglin Hu, Qiu Zhang
Objective. We aim to evaluate the impact of diabetes management shared care clinic (DMSCC) on glycated hemoglobin A1c (HbA1c) compliance and self-management abilities in patients with type 2 diabetes mellitus (T2DM). Methods. This study was a prospective cohort study of patients with T2DM participating in the DMSCC. At baseline and after management, the HbA1c levels were measured, the HbA1c compliance
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Real-World Evidence for Risk Factors of Bruises and Fractures from Falls in Patients with Overactive Bladder: A Medical Record Analysis Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-12-27 Shigero Miyajima, Taisei Omaru, Tatsu Ishii, Hisatomi Arima, Yozo Shibata, Teruaki Izaki, Nobuhiro Haga
Aim. To identify the risk factors for bruises and fractures from falls in patients with overactive bladder (OAB). Methods. We evaluated 1136 patients with OAB and aged ≥50 years who visited our hospital. Age, sex, frequency of nocturnal urination, and urinary incontinence type were investigated in the 360 eligible patients. Patients were divided into three groups: those patients without falls (no-fall
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Changes in Early T-Cell Subsets and Their Impact on Prognosis in Patients with Sepsis: A Single-Center Retrospective Study Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-12-26 Yanhua Li, Youquan Wang, Bin Chen, Jianxing Guo, Dong Zhang
Objective. To analyze the early changes in CD3+, CD4+, and CD8+T-cell subset counts in patients with sepsis and their correlation with prognosis to provide a feasible basis for clinical immunomodulation in sepsis. Methods. This is a single-center retrospective study. The study enrolled sepsis patients (meeting SEPSIS 3.0 definition) who were admitted to the Department of Intensive Care Unit at the
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Association between Elevated Plasma Vitamin B12 and Short-Term Mortality in Elderly Patients Hospitalized in an Internal Medicine Unit Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-12-18 Benjamin Eduin, Camille Roubille, Stéphanie Badiou, Jean Paul Cristol, Pierre Fesler
Background. The prognostic value of vitamin B12 blood levels remains controversial. An association between elevated vitamin B12 and mortality has been reported, particularly among elderly patients with cancers and liver or blood diseases. The present study explored the relationship between mortality and elevated vitamin B12 levels in a population of unscheduled inpatients in an internal medicine unit
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Global, Regional, and National Burden of Ectopic Pregnancy: A 30-Year Observational Database Study Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-12-18 Wang Bo, Zhang Qianyu, Li Mo
Objective. To estimate global, regional, and national trends due to ectopic pregnancy as part of the 2019 Global Burden of Disease study. Methods. We systematically reviewed trends in ectopic pregnancy burden using data from the Global Burden of Disease (GBD) database, including 21 regions, 195 countries, and territories over the past 30 years. The trends of ectopic pregnancy-related incidence, mortality
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Diagnosis, Treatment, and Management for Chronic Coronary Syndrome: A Systematic Review of Clinical Practice Guidelines and Consensus Statements Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-12-18 Tianyue Jing, Yu Wang, Yukun Li, Liangyu Cui, Xingfang Liu, Dasheng Liu, Cong Ren, Tong Yin, Zhiwei Zhao, Jiaheng Wang, Xuejie Han, Liying Wang
Objectives. Management of chronic coronary syndrome (CCS) encompasses a broad spectrum of practices, posing considerable complexity and variability. While guidelines have been established to augment the management quality of CCS, notable disparities persist across their recommendations. This study strives to scrutinize, compare, and reconcile these guideline recommendations pertaining to the diagnosis
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Changes in Serum Concentrations of Bone Turnover Markers in Healthy Pregnant Women Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-12-16 Yiduo Zhang, Ruiying Li, Jing Zhang, Wenjie Zhou, Fan Yu
Background. Changes in bone metabolism during pregnancy have not received sufficient attention because of the lack of effective screening tools. Bone turnover markers (BTMs) could reflect the changes of bone metabolism. Currently, reference intervals for bone metabolism during normal pregnancy are inconclusive. This study aimed to determine reference intervals for BTMs in pregnant women taking prenatal
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Esketamine Combined with Propofol TCI versus Propofol TCI for Deep Sedation during Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: A Prospective, Randomized, and Controlled Trial Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-12-11 Sichen Cui, Peiying Huang, Zhanxiong Wei, Ting Guo, Aiyan Zhang, Lining Huang
Background. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is an invasive procedure that required deep sedation to suppress coughing and body movements. Deep sedation, on the other hand, has been shown to cause respiratory and circulatory depression, especially when the airway is shared with the endoscopist. Esketamine is a novel sedative and analgesic with little respiratory
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Left Ventricular Mass Index in End-Stage Renal Disease Patients during Hemodialysis and Continuous Ambulatory Peritoneal Dialysis Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-12-11 Nghia Nhu Nguyen, Phieu Van Duong, Tan Huynh Ngoc Mai, Nghia Hoang Vo, Dinh Kim Luong, Toan Hoang Ngo
Background. One of the primary reasons for high mortality in end-stage renal disease (ESRD) is cardiovascular disease in patients with renal replacement therapy (RRT). Left ventricular hypertrophy (LVH) significantly predicts mortality and cardiovascular events. Objectives. We assess the left ventricular mass index change in two dialysis methods: hemodialysis (HD) and continuous ambulatory peritoneal
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Quality of Life and Psychometric Characteristics of Syrian Refugee Physicians Who Migrated to Turkey: A Cross-Sectional Study Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-12-6 Ahmet Keskin, Basri Furkan Dagcioglu
Background. The concept of migration comes with various problems, affecting the quality of life and psychological state of immigrants. This study aimed to investigate the quality of life and depression and anxiety states of physicians who immigrated to Turkey after the civil war that started in Syria in 2011. Methods. In this cross-sectional study, a sociodemographic questionnaire form, the short version
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Fluoroscopy Is Essential in Retrograde Intrarenal Surgery Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-11-29 Mehmet Yoldas, Tuba Kuvvet Yoldas
Objective. This study aimed to investigate the necessity of using fluoroscopy in retrograde intrarenal surgery (RIRS). Material and Methods. A total of 612 patients who underwent RIRS for kidney stones were evaluated and divided into two groups. Group 1 routinely underwent the operation with fluoroscopy due to opaque stones (n: 504). In group 2, the procedure was performed without fluoroscopy because
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Empowering Medical Students: Harnessing Artificial Intelligence for Precision Point-of-Care Echocardiography Assessment of Left Ventricular Ejection Fraction Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-11-29 Ziv Dadon, Amir Orlev, Adi Butnaru, David Rosenmann, Michael Glikson, Shmuel Gottlieb, Evan Avraham Alpert
Introduction. Point-of-care ultrasound (POCUS) use is now universal among nonexperts. Artificial intelligence (AI) is currently employed by nonexperts in various imaging modalities to assist in diagnosis and decision making. Aim. To evaluate the diagnostic accuracy of POCUS, operated by medical students with the assistance of an AI-based tool for assessing the left ventricular ejection fraction (LVEF)
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Identification of Crotonylation Metabolism Signature Predicting Overall Survival for Clear Cell Renal Cell Carcinoma Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-11-28 Jie Zheng, Yingqing Liu, Kai Wei, Jiewu Shi, Lin Li, Xuefeng Jiang, Lingsong Tao
Background. Immunotherapy shows promise in treating cancer by leveraging the immune system to combat cancer cells. However, the influence of crotonylation metabolism on the prognosis and tumor environment in ccRCC patients is not fully understood. Methods. We conducted various systematic analyses, including prognosis and cluster analyses, to investigate the role of KAT2A in immunotherapy. We used qRT-PCR
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Influencing Factors of Massive Hemorrhage and High-Grade Renal Vascular Injury after PCNL: A Retrospective Comparative Study Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-11-24 Qiushi He, Ziyan Song, Xinrui Wang, Bingbing Hou, Zongyao Hao
Purpose. Severe hemorrhage after percutaneous nephrolithotomy (PCNL) is a rare but alerting event. In this study, we report the factors affecting massive hemorrhage after PCNL, various levels of vascular damage during renal angiography, and the therapeutic effect of superselective renal artery embolization (SRAE). Patients and Methods. A retrospective analysis was performed on the data of 69 patients
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Diabetes Mellitus and HIV Infection among Newly Diagnosed Pulmonary Tuberculosis Patients in the North West Region of Cameroon: A Cross-Sectional Study Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-11-24 Leonard Fonkeng Sama, Sidoine Sadjeu, Thibau Flaurant Tchouangueu, Solange Dabou, Georges Ful Kuh, Omer Bebe Ngouateu, Michel Noubom
Objective. To determine the prevalence rate of HIV and diabetes among tuberculosis (TB) patients and also the comorbidity rate. Design. Cross-sectional study. Setting. This study was carried out at the Tuberculosis Reference Laboratory, Regional Hospital Bamenda, North West Region of Cameroon, from January 2017 to December 2019. Participants. 1115 cases of pulmonary tuberculosis aged ≥14 years (mean
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The Effect of Various Combinations of Peripheral Nerve Blocks on Postoperative Pain in Laparoscopic Cholecystectomy: A Comparative Prospective Study Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-11-23 Zoya Haitov Ben Zikri, Maryna Volis, Andrei Mazur, Tatjana Orlova, Hana Alon, Sara Bar Yehuda, Vladislav Gofman
Objectives. Most patients who undergo laparoscopic cholecystectomy (LC) experience moderate to severe pain in the first 24 hours after surgery. The transversus abdominal plane (TAP) is currently used for post-LC analgesia. Posterior, subcostal, or rectus sheath TAP blocks are the conventional approaches used. The aim of the current study was to compare the efficacy of combinations of various peripheral
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A Machine Learning-Based Classification of Immunogenic Cell Death Regulators and Characterisation of Immune Microenvironment in Acute Ischemic Stroke Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-11-14 Mengying Wang, Guolian Wei, Shaorui Gu, Zhengyuan Huo, Xue Han
Immunogenic cell death (ICD) regulators exert a crucial part in quite a few in numerous biological processes. This study aimed to determine the function and diagnostic value of ICD regulators in acute ischemic stroke (AIS). 31 significant ICD regulators were identified from the gene expression omnibus (GEO) database in this work (the combination of the GSE16561 dataset and the GSE37587 dataset in the
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Differentiation of Epileptic Brain Abnormalities among Neurological Patients at Taif Region Using MRI Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-11-11 Nahla L. Faizo, Amani A. Alrehaili
This study was conducted to assess the prevalence of epilepsy among different age groups and gender of neurological patients in the Taif region and define the most common brain lesion, affecting epileptic patients living in the Taif city using MRI. Data from 150 patients who were clinically diagnosed with epilepsy and had brain MRIs were analyzed using SPSS. Statistical significance was considered
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The Effects of ICT-Based Interventions on Physical Mobility of Older Adults: A Systematic Literature Review and Meta-Analysis Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-11-10 Hyori Kim, Gahye Kim, Yeonghun Kim, Jiyeon Ha
Systematic literature review and meta-analysis were conducted to integrate and analyze intervention studies dealing with the effects of information and communications technology- (ICT-) based interventions on the physical mobility of older adults in the community. The PubMed/MEDLINE, Embase, CINAHL, and Cochrane CENTRAL databases were searched for studies published from January 2000 to December 2022
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Chronic Low Back Pain with and without Concomitant Osteoarthritis: A Retrospective, Longitudinal Cohort Study of Patients in England Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-11-9 Greg Coates, Peter Clewes, Christoph Lohan, Hannah Stevenson, Robert Wood, Theo Tritton, Roger D. Knaggs, Alastair J. Dickson, David A. Walsh
Objective. Despite the high prevalence of chronic low back pain (CLBP) and osteoarthritis (OA), few estimates of the economic cost of these conditions in England have been published. The aim of the present analysis was to characterise the economic burden of moderate-to-severe pain associated with CLBP + OA and CLBP alone compared with general population-matched controls without CLBP or OA. The primary
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Prevalence of Nonadherence to Medications among Geriatric Patients in Al-Madinah Al-Munawara City’s Hospitals, Kingdom of Saudi Arabia Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-10-31 Haifa Abdulrahman Fadil, Waad Abdulkareem Sammman, Riham Mohamed Elshafie
Introduction. Medication adherence is a major component in the treatment of chronic patients, especially the older adults. It acts as an essential part of a successful therapeutic outcome, increasing treatment benefits, and decreasing hospital admissions, health care utilization, and cost. Limited research regarding medication adherence has been conducted nationwide; however, data among the older adults
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Screening and Colonoscopy Quality Measures: Ethnic Disparities and Impact on Patients’ Outcome Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-10-30 Fadi Abu Baker, Dorin Nicola, Amir Mari, Abdel-Rauf Zeina, Amani Beshara, Randa Taher Natour, Yael Kopelman
Background. Recent reports have confirmed the improving trends in colorectal cancer (CRC) incidence and outcomes. Still, disparities in incidence and mortality in CRC continue to persist between major ethnic groups despite the provision of widespread screening and improved care. We aimed to outline, from an endoscopic point of view, ethnic disparities in major endoscopic measures concerned with CRC
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Gestational Trophoblastic Disease with Coexisting Progressing Pregnancy: Personalised Treatment Modalities Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-10-26 Elena Ulrikh, Elena Dikareva, Igor Govorov, Eduard Komlichenko, Tatiana Pervunina, Olga Li, Oksana Zhamborova, Aminat Dzharbaeva, Viktor Deynega, Veronika Artemenko, Adel Urmancheeva
Purpose. Gestational trophoblastic disease (GTD) coexisting with a steadily progressing pregnancy is an extremely rare condition presented in the literature as a single case or case series of successful delivery. The purpose of this study was to describe five cases of GTD and present possible management strategies for such patients. Methods. Clinical data of five pregnancies with coexisting GTD were
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Serum Hsa_circ_0005962 Is A Prognostic Biomarker of Paclitaxel Resistance in Nonsmall Cell Lung Cancer Treatment Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-10-19 Chenliang Wang, Shaofeng Xia
Background. Tumor progression and the therapeutic resistance associated with cancer agents are thought to be modulated by circular RNAs (circRNAs); however, its mechanism associated with nonsmall cell lung cancer (NSCLC) is still undetermined. The following investigation aimed to evaluate the involvement of circRNAs with NSCLC. Methods. The serum specimens of 146 NSCLC individuals who received complete
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Retinal Microvascular Density and Perfusion during an Insulin-Induced Hypoglycemia Episode: A Warning Call Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-10-16 Gerardo González-Saldivar, José Gerardo González-González, David Robert Chow, Jesús Mohamed-Hamsho, Jesús Hernan González-Cortés, Adriana Sánchez-García, René Rodríguez-Gutiérrez
Aim. To evaluate retinal vascular perfusion and density by optical coherence tomography angiography (OCTA) before, during, and after hypoglycemia in individuals with diabetes mellitus with or without diabetic retinopathy (DR). Methods. A focused clinical history was performed, followed by an ophthalmological examination to document retinopathy status. OCTA was performed at baseline, at hypoglycemia
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Comparison of the Oral Health‐Related Quality of Life, Sleep Quality, and Oral Health Literacy in Sleep and Awake Bruxism: Results from Family Medicine Practice Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-9-30 Melike Mercan Başpınar, Çiğdem Mercan, Metin Mercan, Merve Arslan Aras
Objectives. Bruxism is a common oral behaviour. This study aimed to compare oral health‐related quality of life, sleep quality, and oral health literacy in patients with and without possible sleep bruxism (SB) and awake bruxism (AB). Materials and Methods. A cross-sectional study including 249 volunteers was conducted in a family medicine clinic of a tertiary hospital in Istanbul, Turkey. The American
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Clinical and Epidemiological Characteristics of Rhabdomyolysis: A Retrospective Study Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-9-29 Keke Sun, Zhenhua Shi, Yushanjiang Abudureheman, Qihui Liu, Yibo Zhao, Xiangqun Zhang, Qi Lv, Yan Zhang, Songtao Shou, Heng Jin
Background. Rhabdomyolysis (RM) refers to a clinical syndrome in which muscle cells are damaged by various causes and the clinical manifestations are mainly muscle pain, weakness, and dark urine. Acute kidney injury (AKI) is a serious complication of RM with complex mechanisms and high mortality. Therefore, understanding the pathogenesis and clinical manifestations, early diagnosis and treatment of
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Association of Malnutrition with Risk of Acute Kidney Injury: A Systematic Review and Meta-Analysis Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-9-26 Xiang Xiang, Xinchen Zhu, Lijuan Zhang
Background. Acute kidney injury (AKI) is a complex clinical syndrome of hospitalization that may be affected by undernutrition and metabolic changes. The aim of this meta-analysis was to systematically assess the association between malnutrition and the risk of prevalent AKI. Materials and Methods. We searched PubMed, Embase, Ovid MEDLINE, Web of Science, and Chinese databases (WANFANG, VIP, and CKI)
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Prognostic Value of Neutrophil-to-Lymphocyte Ratio and Vaccination for Negative Conversion Time of Nucleic Acid in Nonsevere COVID-19 Patients Infected by SARS-CoV-2 Omicron Variant Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-9-25 Kongbo Zhu, Shaolei Ma, Hui Chen, Jianfeng Xie, Dan Huang, Zhenghua Hou, Shanhu Qiu, Genshan Ma, Yingzi Huang
SARS-CoV-2 Omicron variant is significantly different from all the previous variants and has rapidly replaced other variants as the dominant variant across the globe. An easily obtained, inexpensive, and rapid marker is needed to predict the negative conversion time (NCT) of nucleic acid in nonsevere COVID-19 patients infected by the Omicron variant. This retrospective study enrolled 226 patients infected
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Clinical Characteristics and Risk Factors for Allergic Rhinitis in Children with Epistaxis Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-8-31 Jing Qing, Yili Cai, Shixiong Tang, Yaowen Wang
Background. Epistaxis is frequently observed in children with allergic rhinitis. However, few studies have addressed the clinical characteristics and risk factors for allergic rhinitis in children with epistaxis. This study aimed to describe the factors associated with allergic rhinitis in children with epistaxis. Methods. In total, we recruited 80 children (aged 3–14 years) who presented with epistaxis
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Leptin Receptor Gln223Arg Polymorphism of Human Spermatozoa Associated with Male Infertility in a Chinese Population Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-8-23 Yi Mo, Fangfang Liang, Arshad Mehmood, Suleman Shah, Ying Xie, Zhong Lin, Yan Sun, Hesheng Jiang, Yafen Guo, Xiangli Niu, Dinggan Mo
Background. Leptin (LEP) is believed to play a crucial role in male reproduction, while the molecular mechanisms through which LEP affects the male reproductive system are unclear. LEP acts by binding to a leptin receptor (LEPR) which mediates its physiological action, but there are only limited studies on the function of LEPR in human sperm. Purpose. This study aimed to determine the Gln223Arg polymorphisms
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The Possible Mediatory Role of Inflammatory Markers on the Association of Dietary Insulin Index and Insulin Load with Metabolic Syndrome in Women with Overweight and Obesity: A Cross-Sectional Study Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-8-21 Melika Darzi, Farideh Shiraseb, Alessandra da Silva, Josefina Bressan, Cain C. T. Clark, Sara Mahmoodi, Khadijeh Mirzaei
Background. Metabolic syndrome (MetS) is associated with increased inflammation. Diet plays an important role in the prevention and management of MetS, while some dietary factors can also increase or decrease markers of systemic inflammation. In this study, we aimed to determine the mediated association of inflammatory markers induced by dietary insulin index (DII) and dietary insulin load (DIL) with
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Prognostic Factors and a Predictive Nomogram of Cancer-Specific Survival of Epithelial Ovarian Cancer Patients with Pelvic Exenteration Treatment Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-8-17 Ting Wang, Xin Fu, Lei Zhang, Shuna Liu, Ziqi Tao, Fang Wang
Objective. The aim of this study was to explore prognostic factors, develop and internally validate a prognostic nomogram model, and predict the cancer-specific survival (CCS) of epithelial ovarian cancer (EOC) patients with pelvic exenteration (PE) treatment. Methods. A total of 454 EOC patients from the Surveillance, Epidemiology, and End Results (SEER) database were collected according to the inclusion
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The Efficacy and Safety of Teprotumumab in Thyroid Eye Disease: Evidence from Randomized Controlled Trials Int. J. Clin. Pract. (IF 2.6) Pub Date : 2023-8-8 Fei Lin, Qiu’e Yao, Bin Yu, Zehui Deng, Jingyue Qiu, Rong He
In this study, we conducted a meta-analysis to assess the efficacy and safety of teprotumumab in treating thyroid eye disease. We searched the Cochrane Library, PubMed, and Embase databases from inception to May 25, 2022, and included all randomized controlled trials. Odds ratios (ORs) were calculated using fixed- or random-effect models. A total of three studies involving 341 patients were identified